PL2991683T3 - Koniugaty glikoproteiny lub glikanu z toksycznym ładunkiem - Google Patents
Koniugaty glikoproteiny lub glikanu z toksycznym ładunkiemInfo
- Publication number
- PL2991683T3 PL2991683T3 PL14725209T PL14725209T PL2991683T3 PL 2991683 T3 PL2991683 T3 PL 2991683T3 PL 14725209 T PL14725209 T PL 14725209T PL 14725209 T PL14725209 T PL 14725209T PL 2991683 T3 PL2991683 T3 PL 2991683T3
- Authority
- PL
- Poland
- Prior art keywords
- glycan
- glycoprotein
- conjugates
- toxic payload
- payload
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 150000004676 glycans Chemical class 0.000 title 1
- 231100000331 toxic Toxicity 0.000 title 1
- 230000002588 toxic effect Effects 0.000 title 1
Classifications
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- A61K38/08—Peptides having 5 to 11 amino acids
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- Chemical Kinetics & Catalysis (AREA)
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| PCT/FI2014/050322 WO2014177771A1 (en) | 2013-05-02 | 2014-05-02 | Conjugates of a glycoprotein or a glycan with a toxic payload |
| EP14725209.2A EP2991683B1 (en) | 2013-05-02 | 2014-05-02 | Conjugates of a glycoprotein or a glycan with a toxic payload |
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| US9732161B2 (en) | 2012-06-26 | 2017-08-15 | Sutro Biopharma, Inc. | Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use |
| US9682934B2 (en) | 2012-08-31 | 2017-06-20 | Sutro Biopharma, Inc. | Modified amino acids |
| HRP20230690T1 (hr) * | 2012-10-23 | 2023-10-13 | Synaffix B.V. | Modificirano antitijelo, konjugat antitijela i postupak za njihovo pripremanje |
| WO2014066733A2 (en) | 2012-10-25 | 2014-05-01 | Life Technologies Corporation | Methods and compositions for enzyme-mediated site-specific radiolabeling of glycoproteins |
| US20150314007A1 (en) * | 2012-12-21 | 2015-11-05 | Glykos Finland Oy | Linker-payload molecule conjugates |
| HUE033626T2 (en) | 2013-02-14 | 2017-12-28 | Bristol Myers Squibb Co | Tubulysin compounds, methods of preparation and use |
| GB2511137A (en) | 2013-02-26 | 2014-08-27 | Glykos Finland Oy | Chelator Molecule |
| WO2014143241A1 (en) | 2013-03-15 | 2014-09-18 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
| PL2991683T3 (pl) * | 2013-05-02 | 2020-03-31 | Glykos Finland Oy | Koniugaty glikoproteiny lub glikanu z toksycznym ładunkiem |
| WO2014189370A1 (en) | 2013-05-24 | 2014-11-27 | Stichting Katholieke Universiteit | Substituted azadibenzocyclooctyne compounds and their use in metal-free click reactions |
| CA2914189C (en) | 2013-06-21 | 2023-03-14 | Innate Pharma | Enzymatic conjugation of polypeptides |
| JP2016538878A (ja) | 2013-10-14 | 2016-12-15 | シンアフィックス ビー.ブイ. | 糖鎖工学的に操作された抗体、抗体コンジュゲート、及びそれらの調製方法 |
| WO2015057065A1 (en) | 2013-10-14 | 2015-04-23 | Synaffix B.V. | Glycoengineered antibody, antibody-conjugate and methods for their preparation |
| US9987373B2 (en) | 2013-10-14 | 2018-06-05 | Synaffix B.V. | Modified glycoprotein, protein-conjugate and process for the preparation thereof |
| JP2016538877A (ja) | 2013-10-14 | 2016-12-15 | シンアフィックス ビー.ブイ. | 修飾糖タンパク質、タンパク質コンジュゲート及びそれらの調製方法 |
| EP2910561A1 (de) | 2014-02-25 | 2015-08-26 | Reinhard Brossmer | Sialinsäurederivate |
| CN108883191B (zh) | 2016-02-08 | 2022-10-14 | 西纳福克斯股份有限公司 | 用于靶向cd30肿瘤的具有改善的治疗指数的抗体-缀合物以及用于改善抗体-缀合物的治疗指数的方法 |
| US10874746B2 (en) | 2016-02-08 | 2020-12-29 | Synaffix B.V. | Sulfamide linkers for use in bioconjugates |
| US10858641B2 (en) | 2016-02-08 | 2020-12-08 | Synaffix B.V. | Enzymes for trimming of glycoproteins |
-
2014
- 2014-05-02 PL PL14725209T patent/PL2991683T3/pl unknown
- 2014-05-02 EP EP14725209.2A patent/EP2991683B1/en active Active
- 2014-05-02 LT LTEP14725209.2T patent/LT2991683T/lt unknown
- 2014-05-02 WO PCT/FI2014/050322 patent/WO2014177771A1/en not_active Ceased
- 2014-05-02 SI SI201431408T patent/SI2991683T1/sl unknown
- 2014-05-02 EP EP19195922.0A patent/EP3613468A1/en not_active Withdrawn
- 2014-05-02 US US14/888,545 patent/US20160106860A1/en not_active Abandoned
- 2014-05-02 ES ES14725209T patent/ES2759503T3/es active Active
- 2014-05-02 DK DK14725209T patent/DK2991683T3/da active
-
2017
- 2017-09-14 US US15/704,026 patent/US10973922B2/en active Active
-
2021
- 2021-03-23 US US17/209,356 patent/US11723983B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3613468A1 (en) | 2020-02-26 |
| DK2991683T3 (da) | 2019-11-04 |
| SI2991683T1 (sl) | 2020-01-31 |
| US20210252158A1 (en) | 2021-08-19 |
| ES2759503T3 (es) | 2020-05-11 |
| LT2991683T (lt) | 2019-12-27 |
| US20180256732A1 (en) | 2018-09-13 |
| US11723983B2 (en) | 2023-08-15 |
| US20160106860A1 (en) | 2016-04-21 |
| EP2991683A1 (en) | 2016-03-09 |
| WO2014177771A1 (en) | 2014-11-06 |
| EP2991683B1 (en) | 2019-09-18 |
| US10973922B2 (en) | 2021-04-13 |
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