PL2991683T3 - Koniugaty glikoproteiny lub glikanu z toksycznym ładunkiem - Google Patents

Koniugaty glikoproteiny lub glikanu z toksycznym ładunkiem

Info

Publication number
PL2991683T3
PL2991683T3 PL14725209T PL14725209T PL2991683T3 PL 2991683 T3 PL2991683 T3 PL 2991683T3 PL 14725209 T PL14725209 T PL 14725209T PL 14725209 T PL14725209 T PL 14725209T PL 2991683 T3 PL2991683 T3 PL 2991683T3
Authority
PL
Poland
Prior art keywords
glycan
glycoprotein
conjugates
toxic payload
payload
Prior art date
Application number
PL14725209T
Other languages
English (en)
Inventor
Tero Satomaa
Jari Helin
Filip S. EKHOLM
Original Assignee
Glykos Finland Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glykos Finland Oy filed Critical Glykos Finland Oy
Publication of PL2991683T3 publication Critical patent/PL2991683T3/pl

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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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EP2935608A1 (en) 2013-10-14 2015-10-28 SynAffix B.V. Modified glycoprotein, protein-conjugate and process for the preparation thereof
EP3057618B1 (en) 2013-10-14 2022-12-14 SynAffix B.V. Glycoengineered antibody, antibody-conjugate and methods for their preparation
WO2015057066A1 (en) 2013-10-14 2015-04-23 Synaffix B.V. Glycoengineered antibody, antibody-conjugate and methods for their preparation
EP2910561A1 (de) 2014-02-25 2015-08-26 Reinhard Brossmer Sialinsäurederivate
EP3413916A1 (en) 2016-02-08 2018-12-19 Synaffix B.V. Antibody-conjugates with improved therapeutic index for targeting cd30 tumours and method for improving therapeutic index of antibody-conjugates
US10858641B2 (en) 2016-02-08 2020-12-08 Synaffix B.V. Enzymes for trimming of glycoproteins
WO2017137423A1 (en) 2016-02-08 2017-08-17 Synaffix B.V. Improved sulfamide linkers for use in bioconjugates

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EP2991683A1 (en) 2016-03-09
US20180256732A1 (en) 2018-09-13
SI2991683T1 (sl) 2020-01-31
US10973922B2 (en) 2021-04-13
EP2991683B1 (en) 2019-09-18
WO2014177771A1 (en) 2014-11-06
LT2991683T (lt) 2019-12-27
DK2991683T3 (da) 2019-11-04
US20210252158A1 (en) 2021-08-19
US20160106860A1 (en) 2016-04-21
US11723983B2 (en) 2023-08-15
ES2759503T3 (es) 2020-05-11
EP3613468A1 (en) 2020-02-26

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