WO2017137457A1 - Antibody-conjugates with improved therapeutic index for targeting cd30 tumours and method for improving therapeutic index of antibody-conjugates - Google Patents

Antibody-conjugates with improved therapeutic index for targeting cd30 tumours and method for improving therapeutic index of antibody-conjugates Download PDF

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Publication number
WO2017137457A1
WO2017137457A1 PCT/EP2017/052790 EP2017052790W WO2017137457A1 WO 2017137457 A1 WO2017137457 A1 WO 2017137457A1 EP 2017052790 W EP2017052790 W EP 2017052790W WO 2017137457 A1 WO2017137457 A1 WO 2017137457A1
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WO
WIPO (PCT)
Prior art keywords
groups
group
ch2
according
formula
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Application number
PCT/EP2017/052790
Other languages
French (fr)
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WO2017137457A9 (en
Inventor
Sander Sebastiaan Van Berkel
Jorge Merijn Mathieu Verkade
Maria Antonia WIJDEVEN
Ryan HEESBEEN
Petrus Josephus Jacobus Maria VAN DE SANDE
Remon VAN GEEL
Brian Maria Gerardus JANSSEN
Inge Catharina Josephina HURKMANS
Floris Louis Van Delft
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Synaffix B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority to EP16154712 priority Critical
Priority to EP16154739 priority
Priority to EP16154712.0 priority
Priority to EP16154739.3 priority
Priority to EP16173595 priority
Priority to EP16173595.6 priority
Priority to JP2016-155929 priority
Priority to JP2016155929A priority patent/JP2017200902A/en
Application filed by Synaffix B.V. filed Critical Synaffix B.V.
Priority claimed from US16/076,293 external-priority patent/US20190262466A1/en
Publication of WO2017137457A1 publication Critical patent/WO2017137457A1/en
Publication of WO2017137457A9 publication Critical patent/WO2017137457A9/en

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