IT1396620B1 - Analoghi chimerici - Google Patents

Analoghi chimerici

Info

Publication number
IT1396620B1
IT1396620B1 ITMI2009A002071A ITMI20092071A IT1396620B1 IT 1396620 B1 IT1396620 B1 IT 1396620B1 IT MI2009A002071 A ITMI2009A002071 A IT MI2009A002071A IT MI20092071 A ITMI20092071 A IT MI20092071A IT 1396620 B1 IT1396620 B1 IT 1396620B1
Authority
IT
Italy
Prior art keywords
chemical analogues
analogues
chemical
Prior art date
Application number
ITMI2009A002071A
Other languages
English (en)
Inventor
Susanna Veronesi
Emanuela Peschechera
Paolo Alberto Veronesi
Pablo E A Rodriguez
Anna Maria Veronesi
Original Assignee
Therapicon Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ITMI2009A002071A priority Critical patent/IT1396620B1/it
Application filed by Therapicon Srl filed Critical Therapicon Srl
Priority to EP10782299.1A priority patent/EP2504326B1/en
Priority to CN201080052258.6A priority patent/CN102639520B/zh
Priority to JP2012540431A priority patent/JP2013512222A/ja
Priority to CA2780033A priority patent/CA2780033A1/en
Priority to PCT/EP2010/068229 priority patent/WO2011064303A1/en
Priority to BR112012011703A priority patent/BR112012011703A2/pt
Priority to US13/512,306 priority patent/US9284292B2/en
Priority to KR1020127013207A priority patent/KR20120101397A/ko
Priority to AU2010323104A priority patent/AU2010323104A1/en
Publication of ITMI20092071A1 publication Critical patent/ITMI20092071A1/it
Application granted granted Critical
Publication of IT1396620B1 publication Critical patent/IT1396620B1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14Nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056Triazole or tetrazole radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ITMI2009A002071A 2009-11-25 2009-11-25 Analoghi chimerici IT1396620B1 (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
ITMI2009A002071A IT1396620B1 (it) 2009-11-25 2009-11-25 Analoghi chimerici
CN201080052258.6A CN102639520B (zh) 2009-11-25 2010-11-25 唾液酸模拟性化合物
JP2012540431A JP2013512222A (ja) 2009-11-25 2010-11-25 シアロキメラ化合物
CA2780033A CA2780033A1 (en) 2009-11-25 2010-11-25 Sialochimeric compounds
EP10782299.1A EP2504326B1 (en) 2009-11-25 2010-11-25 Sialochimeric compounds
PCT/EP2010/068229 WO2011064303A1 (en) 2009-11-25 2010-11-25 Sialochimeric compounds
BR112012011703A BR112012011703A2 (pt) 2009-11-25 2010-11-25 composto, composição farmacêutica, e, uso de um composto
US13/512,306 US9284292B2 (en) 2009-11-25 2010-11-25 Sialochimeric compounds
KR1020127013207A KR20120101397A (ko) 2009-11-25 2010-11-25 시알로키메릭 화합물
AU2010323104A AU2010323104A1 (en) 2009-11-25 2010-11-25 Sialochimeric compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2009A002071A IT1396620B1 (it) 2009-11-25 2009-11-25 Analoghi chimerici

Publications (2)

Publication Number Publication Date
ITMI20092071A1 ITMI20092071A1 (it) 2011-05-26
IT1396620B1 true IT1396620B1 (it) 2012-12-14

Family

ID=42236894

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI2009A002071A IT1396620B1 (it) 2009-11-25 2009-11-25 Analoghi chimerici

Country Status (10)

Country Link
US (1) US9284292B2 (it)
EP (1) EP2504326B1 (it)
JP (1) JP2013512222A (it)
KR (1) KR20120101397A (it)
CN (1) CN102639520B (it)
AU (1) AU2010323104A1 (it)
BR (1) BR112012011703A2 (it)
CA (1) CA2780033A1 (it)
IT (1) IT1396620B1 (it)
WO (1) WO2011064303A1 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103509066B (zh) * 2012-06-25 2016-03-30 沈阳药科大学 一种含有唾液酸片段的脂质衍生物及其应用
CN104031097B (zh) * 2013-03-04 2016-12-28 沈阳药科大学 一种含有唾液酸基团的脂质衍生物及其应用
SI2991683T1 (sl) 2013-05-02 2020-01-31 Glykos Finland Oy Konjugati glikoproteina ali glikana s toksično obremenitvijo
ES2785551T3 (es) 2014-06-30 2020-10-07 Glykos Finland Oy Derivado de sacárido de una carga útil tóxica y sus conjugados con anticuerpos
CN116003486B (zh) * 2023-03-27 2023-08-01 北京天之泰生物科技有限公司 一种先导化合物、其制备方法、以及其在制备抗流感病毒药物方面的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK282950B6 (sk) 1990-04-24 2003-01-09 Biota Scientific Management Pty Ltd Deriváty alfa-D-neuramínovej kyseliny, spôsob ich prípravy, ich použitie a farmaceutické prípravky na ich báze
WO1992006691A1 (en) 1990-10-19 1992-04-30 Biota Scientific Management Pty. Ltd. Anti-viral compounds that bind the active site of influenza neuramidase and display in vivo activity against orthomyxovirus and paramyxovirus
CA2081068C (en) 1991-10-23 2005-11-29 Laurence Mark Von Itzstein Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of .alpha.-d-neuraminic acid
MX9706496A (es) 1995-02-27 1997-11-29 Gilead Sciences Inc Nuevos inhibidores selectivos de las neuroaminidasas virales o bacterianas.
CA2315262C (en) 1997-12-17 2009-11-10 Biocryst Pharmaceuticals, Inc. Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors
AUPP913999A0 (en) * 1999-03-12 1999-04-01 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
DE19930177B4 (de) * 1999-06-30 2007-02-08 Nikolai Vladimirovich Bovin Intermolekular assoziierende Verbindungen und deren Verwendung
WO2008090151A1 (en) * 2007-01-23 2008-07-31 Therapicon Srl Antiviral compounds
KR101496913B1 (ko) 2010-11-03 2015-03-02 삼성전자 주식회사 로봇청소기와 자동배출 스테이션 및 이를 가지는 로봇청소기 시스템

Also Published As

Publication number Publication date
EP2504326B1 (en) 2016-10-19
EP2504326A1 (en) 2012-10-03
AU2010323104A1 (en) 2012-06-21
US20120269771A1 (en) 2012-10-25
KR20120101397A (ko) 2012-09-13
BR112012011703A2 (pt) 2016-03-01
US9284292B2 (en) 2016-03-15
AU2010323104A8 (en) 2012-07-19
CN102639520B (zh) 2016-08-03
JP2013512222A (ja) 2013-04-11
CN102639520A (zh) 2012-08-15
CA2780033A1 (en) 2011-06-03
WO2011064303A1 (en) 2011-06-03
ITMI20092071A1 (it) 2011-05-26

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IT1396620B1 (it) Analoghi chimerici