|
ATE193551T1
(de)
|
1991-03-18 |
2000-06-15 |
Scripps Research Inst |
Oligosaccharide als enzymsubstrate und - inhibitoren: verfahren und zusammensetzungen
|
|
SK42594A3
(en)
*
|
1991-10-15 |
1994-10-05 |
Scripps Research Inst |
Method of production of fucosylated carbohydrates
|
|
US5559103A
(en)
*
|
1993-07-21 |
1996-09-24 |
Cytel Corporation |
Bivalent sialyl X saccharides
|
|
DE4408248A1
(de)
*
|
1994-03-11 |
1995-09-14 |
Hoechst Ag |
Physiologisch verträgliche und physiologisch abbaubare Kohlenhydrat-Mimetika, ein Verfahren zur Herstellung und ihre Verwendung
|
|
EP0671409A3
(de)
*
|
1994-03-11 |
1996-06-12 |
Hoechst Ag |
Malonsäurederivate mit antiadhäsiven Eigenschaften.
|
|
IT1268954B1
(it)
*
|
1994-03-11 |
1997-03-18 |
Fidia Advanced Biopolymers Srl |
Processo per la preparazione di acido ialuronico mediante sintesienzimatica e relative composizioni farmaceutiche
|
|
US6030815A
(en)
*
|
1995-04-11 |
2000-02-29 |
Neose Technologies, Inc. |
Enzymatic synthesis of oligosaccharides
|
|
US5922577A
(en)
*
|
1995-04-11 |
1999-07-13 |
Cytel Corporation |
Enzymatic synthesis of glycosidic linkages
|
|
US5876980A
(en)
*
|
1995-04-11 |
1999-03-02 |
Cytel Corporation |
Enzymatic synthesis of oligosaccharides
|
|
US5728554A
(en)
*
|
1995-04-11 |
1998-03-17 |
Cytel Corporation |
Enzymatic synthesis of glycosidic linkages
|
|
WO1997037682A1
(en)
*
|
1996-04-10 |
1997-10-16 |
Cytel Corporation |
Nucleic acids encoding gdp-fucose pyrophosphorylase
|
|
ES2218806T3
(es)
|
1997-01-16 |
2004-11-16 |
Neose Technologies, Inc. |
Sialilacion practica in vitro de glicoproteinas recombinantes.
|
|
US5952203A
(en)
*
|
1997-04-11 |
1999-09-14 |
The University Of British Columbia |
Oligosaccharide synthesis using activated glycoside derivative, glycosyl transferase and catalytic amount of nucleotide phosphate
|
|
EP1903114A3
(de)
|
1997-12-01 |
2008-07-23 |
Neose Technologies, Inc. |
Enzymatische Synthese von Gangliosiden
|
|
ATE355295T1
(de)
|
1998-10-06 |
2006-03-15 |
Massachusetts Inst Technology |
Synthese von oligosacchariden, reagenzien und verfahren
|
|
US6699705B2
(en)
|
1999-02-01 |
2004-03-02 |
National Research Council Of Canada |
Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
|
|
US6503744B1
(en)
|
1999-02-01 |
2003-01-07 |
National Research Council Of Canada |
Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
|
|
JP2002537796A
(ja)
*
|
1999-03-02 |
2002-11-12 |
ヒューマン ジノーム サイエンシーズ, インコーポレイテッド |
ヒトグリコシル化酵素
|
|
US6949372B2
(en)
|
1999-03-02 |
2005-09-27 |
The Johns Hopkins University |
Engineering intracellular sialylation pathways
|
|
AUPP913999A0
(en)
*
|
1999-03-12 |
1999-04-01 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
|
US6395559B1
(en)
|
1999-05-04 |
2002-05-28 |
Orchid Biosciences, Inc. |
Multiple fluid sample processor with single well addressability
|
|
EP1185269B1
(de)
*
|
1999-05-24 |
2007-11-14 |
Abaron Biosciences, Inc. |
Glycosyltransferase inhibitoren
|
|
KR100349696B1
(ko)
*
|
1999-06-30 |
2002-08-22 |
주식회사 하이닉스반도체 |
화학적 팽창 공정을 이용한 반도체 소자의 금속배선 형성을 위한 대머신 구조 형성방법
|
|
EP1189643A1
(de)
*
|
1999-06-30 |
2002-03-27 |
Novartis AG |
Ophthalmischer formkörper
|
|
FI19992070A7
(fi)
|
1999-09-28 |
2001-03-29 |
Carbion Oy |
Uudet fukosyloidut oligosakkaridit ja menetelmä niiden valmistamiseksi
|
|
JP4599505B2
(ja)
*
|
2000-03-03 |
2010-12-15 |
明治乳業株式会社 |
N−アセチル−β−ヘキソサミニド誘導体の製造方法
|
|
KR100446483B1
(ko)
*
|
2000-03-31 |
2004-09-01 |
미시간 스테이트 유니버시티 |
옥심 또는 이민으로부터 1,5-디데옥시-1,5-이미노 헥시톨제조방법
|
|
US6586207B2
(en)
|
2000-05-26 |
2003-07-01 |
California Institute Of Technology |
Overexpression of aminoacyl-tRNA synthetases for efficient production of engineered proteins containing amino acid analogues
|
|
US7863020B2
(en)
*
|
2000-06-28 |
2011-01-04 |
Glycofi, Inc. |
Production of sialylated N-glycans in lower eukaryotes
|
|
JP2005527467A
(ja)
|
2001-08-29 |
2005-09-15 |
ネオーズ テクノロジーズ, インコーポレイテッド |
新規な合成ガングリオシド誘導体およびその組成物
|
|
CA2459040A1
(en)
*
|
2001-09-14 |
2003-03-27 |
Mimeon, Inc. |
Methods of making glycolmolecules with enhanced activities and uses thereof
|
|
EP2305312B1
(de)
|
2001-10-10 |
2015-03-04 |
ratiopharm GmbH |
Neumodulierung und Glykokonjugation von Follitropin (FSH)
|
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
|
AUPR879501A0
(en)
*
|
2001-11-09 |
2001-12-06 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
|
US6852485B1
(en)
|
2002-01-22 |
2005-02-08 |
California State University Fullerton Foundation |
Method for identifying a compound for the treatment of microorganism infections by inhibiting energy storage and utilization in pathogens
|
|
WO2004009838A2
(en)
|
2002-07-23 |
2004-01-29 |
Neose Technologies, Inc. |
H. Pylori FUCOSYLTRANSFERASES
|
|
EP1636248A4
(de)
|
2002-12-16 |
2006-09-06 |
Halozyme Inc |
Humanes chondroitinase-glycoprotein(chasegp), verfahren zu seiner herstellung und dieses enthaltendepharmazeutische zusammensetzungen
|
|
AU2004218354B2
(en)
|
2003-03-05 |
2009-10-01 |
Halozyme, Inc. |
Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof
|
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
|
NZ542148A
(en)
|
2003-03-06 |
2008-05-30 |
Neose Technologies Inc |
Methods and compositions for the enzymatic synthesis of gangliosides
|
|
EP1615945B1
(de)
|
2003-04-09 |
2011-09-28 |
BioGeneriX AG |
Glycopegylierungsverfahren und durch die verfahren hergestellte proteine/peptide
|
|
WO2006127896A2
(en)
|
2005-05-25 |
2006-11-30 |
Neose Technologies, Inc. |
Glycopegylated factor ix
|
|
EP1644390B1
(de)
*
|
2003-06-24 |
2011-04-20 |
Isis Innovation Limited |
Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen
|
|
WO2005012484A2
(en)
|
2003-07-25 |
2005-02-10 |
Neose Technologies, Inc. |
Antibody-toxin conjugates
|
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
|
EP1718739B1
(de)
|
2004-02-04 |
2011-07-13 |
Novo Nordisk A/S |
Verfahren zur rückfaltung von säuger-glycosyltransferasen
|
|
US20050287639A1
(en)
|
2004-05-17 |
2005-12-29 |
California Institute Of Technology |
Methods of incorporating amino acid analogs into proteins
|
|
EP1814573B1
(de)
|
2004-10-29 |
2016-03-09 |
ratiopharm GmbH |
Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf)
|
|
CA2593682C
(en)
|
2005-01-10 |
2016-03-22 |
Neose Technologies, Inc. |
Glycopegylated granulocyte colony stimulating factor
|
|
EP1871795A4
(de)
|
2005-04-08 |
2010-03-31 |
Biogenerix Ag |
Zusammensetzungen und verfahren zur herstellung von glycosylierungsmutanten eines proteaseresistenten menschlichen wachstumshormons
|
|
US7820422B2
(en)
|
2005-06-16 |
2010-10-26 |
Centre National De La Recherche Scientifique (Cnrs) |
Efficient production of oligosaccharides using metabolically engineered microorganisms
|
|
US8771991B2
(en)
|
2005-08-11 |
2014-07-08 |
National Research Council Of Canada |
SOAT polypeptide reaction mixture
|
|
US20070105755A1
(en)
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
|
JP2009526746A
(ja)
|
2005-08-19 |
2009-07-23 |
セントカー・インコーポレーテツド |
タンパク質分解抵抗性の抗体調製物
|
|
JP2009511082A
(ja)
*
|
2005-10-17 |
2009-03-19 |
ヘルス リサーチ インコーポレイテッド |
糖類のためのトランスフェラーゼに特異的な受容体並びにその入手及び使用方法
|
|
WO2007056191A2
(en)
|
2005-11-03 |
2007-05-18 |
Neose Technologies, Inc. |
Nucleotide sugar purification using membranes
|
|
EP1999259B1
(de)
|
2006-03-03 |
2014-06-25 |
California Institute of Technology |
Ortsspezifische inkorporation von aminosäuren in moleküle
|
|
WO2007130453A2
(en)
|
2006-05-02 |
2007-11-15 |
Allozyne, Inc. |
Non-natural amino acid substituted polypeptides
|
|
AR078117A1
(es)
|
2006-06-20 |
2011-10-19 |
Protech Pharma S A |
Una muteina recombinante del interferon alfa humano glicosilado, un gen que codifica para dicha muteina, un metodo de produccion de dicho gen, un metodo para obtener una celula eucariota productora de dicha muteina, un metodo para producir dicha muteina, un procedimiento para purificar dicha muteina
|
|
US9187532B2
(en)
|
2006-07-21 |
2015-11-17 |
Novo Nordisk A/S |
Glycosylation of peptides via O-linked glycosylation sequences
|
|
CA2665332A1
(en)
|
2006-10-03 |
2008-04-10 |
Centre National De La Recherche Scientifique (Cnrs) |
High yield production of sialic acid (neu5ac) by fermentation
|
|
US20100075375A1
(en)
|
2006-10-03 |
2010-03-25 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates
|
|
CA2665480C
(en)
|
2006-10-04 |
2019-11-12 |
Novo Nordisk A/S |
Glycerol linked pegylated sugars and glycopeptides
|
|
EP1911850A1
(de)
*
|
2006-10-09 |
2008-04-16 |
Centre National De La Recherche Scientifique (Cnrs) |
Verfahren zur Herstellung von 6-thio-sialierten Glykoproteinen und Glycokonjugaten
|
|
CN101652377A
(zh)
*
|
2007-04-02 |
2010-02-17 |
泰拉科斯有限公司 |
苄基化糖苷衍生物及其用法
|
|
CN101796063B
(zh)
|
2007-04-03 |
2017-03-22 |
拉蒂奥法姆有限责任公司 |
使用糖聚乙二醇化g‑csf的治疗方法
|
|
CA2682738A1
(en)
|
2007-04-16 |
2008-10-23 |
Momenta Pharmaceuticals, Inc. |
Defined glycoprotein products and related methods
|
|
WO2008154639A2
(en)
|
2007-06-12 |
2008-12-18 |
Neose Technologies, Inc. |
Improved process for the production of nucleotide sugars
|
|
US8999954B2
(en)
*
|
2007-07-03 |
2015-04-07 |
Childern's Hospital & Research Center at Oakland |
Inhibitors of polysialic acid de-N-acetylase and methods for using the same
|
|
JP5523313B2
(ja)
|
2007-07-03 |
2014-06-18 |
チルドレンズ ホスピタル アンド リサーチ センター アット オークランド |
ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用
|
|
JP5702600B2
(ja)
*
|
2007-07-03 |
2015-04-15 |
チルドレンズ ホスピタル アンド リサーチ センター アット オークランド |
オリゴシアル酸誘導体、製造方法および免疫学的使用
|
|
WO2009045894A1
(en)
|
2007-09-28 |
2009-04-09 |
Centocor, Inc. |
Methods and structural conformations of antibody preparations with increased resistance to proteases
|
|
JP4826824B2
(ja)
*
|
2007-12-03 |
2011-11-30 |
クミアイ化学工業株式会社 |
オリゴ糖
|
|
CN103497247A
(zh)
|
2008-02-27 |
2014-01-08 |
诺沃—诺迪斯克有限公司 |
缀合的因子viii分子
|
|
WO2010111530A1
(en)
|
2009-03-25 |
2010-09-30 |
Seneb Biosciences, Inc. |
Glycolipids as treatment for disease
|
|
CA2793276A1
(en)
*
|
2009-03-27 |
2010-09-30 |
Zacharon Pharmaceuticals, Inc. |
Ganglioside biosynthesis modulators
|
|
CA2768155C
(en)
|
2009-06-16 |
2016-08-23 |
The University Of Bath |
Materials and methods relating to glycosylation
|
|
BR112012010252A2
(pt)
|
2009-10-29 |
2016-12-06 |
Janssen Biotech Inc |
variantes de glicosilação de anticorpo
|
|
US9921210B2
(en)
|
2010-04-07 |
2018-03-20 |
Momenta Pharmaceuticals, Inc. |
High mannose glycans
|
|
JP2014510045A
(ja)
|
2011-02-08 |
2014-04-24 |
ハロザイム インコーポレイテッド |
ヒアルロナン分解酵素の組成物および脂質製剤ならびに良性前立腺肥大症の治療のためのその使用
|
|
US9170249B2
(en)
|
2011-03-12 |
2015-10-27 |
Momenta Pharmaceuticals, Inc. |
N-acetylhexosamine-containing N-glycans in glycoprotein products
|
|
US20130011378A1
(en)
|
2011-06-17 |
2013-01-10 |
Tzung-Horng Yang |
Stable formulations of a hyaluronan-degrading enzyme
|
|
KR101828828B1
(ko)
|
2011-10-24 |
2018-03-29 |
할로자임, 아이엔씨 |
항-히알루로난 제제 치료를 위한 동반 진단 및 이의 사용 방법
|
|
BR112014016195A2
(pt)
|
2011-12-30 |
2020-10-27 |
Halozyme, Inc. |
variantes de polipeptídio ph20, formulações e usos das mesmas
|
|
WO2013181575A2
(en)
|
2012-06-01 |
2013-12-05 |
Momenta Pharmaceuticals, Inc. |
Methods related to denosumab
|
|
US20150210753A1
(en)
|
2012-07-26 |
2015-07-30 |
Momenta Pharmaceuticals, Inc. |
Glycoproteins with anti-inflammatory properties
|
|
TWI563092B
(en)
*
|
2012-08-20 |
2016-12-21 |
Academia Sinica |
Large scale enzymatic synthesis of oligosaccharides
|
|
US10450361B2
(en)
|
2013-03-15 |
2019-10-22 |
Momenta Pharmaceuticals, Inc. |
Methods related to CTLA4-Fc fusion proteins
|
|
SI2991683T1
(sl)
|
2013-05-02 |
2020-01-31 |
Glykos Finland Oy |
Konjugati glikoproteina ali glikana s toksično obremenitvijo
|
|
ES2708759T3
(es)
|
2013-05-13 |
2019-04-11 |
Momenta Pharmaceuticals Inc |
Procedimientos para el tratamiento de la neurodegeneración
|
|
US10086054B2
(en)
*
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
|
WO2015057622A1
(en)
|
2013-10-16 |
2015-04-23 |
Momenta Pharmaceuticals, Inc. |
Sialylated glycoproteins
|
|
EP3240411A4
(de)
*
|
2014-11-12 |
2019-02-20 |
Tumorend LLC |
Zusammensetzungen, verfahren und behandlungen zur hemmung der zelladhäsion und virusbindung und penetration
|
|
WO2018114879A1
(en)
|
2016-12-21 |
2018-06-28 |
F. Hoffmann-La Roche Ag |
Method for in vitro glycoengineering of antibodies
|
|
CN110100007B
(zh)
|
2016-12-21 |
2024-05-28 |
豪夫迈·罗氏有限公司 |
用于体外糖工程化抗体的酶的再使用
|
|
CA3044920C
(en)
|
2016-12-21 |
2022-06-28 |
Roberto Falkenstein |
In vitro glycoengineering of antibodies
|
|
CN106632531B
(zh)
*
|
2017-01-03 |
2019-02-22 |
河南科技学院 |
一种α-2,3羟乙酰唾液酸乳果糖的制备方法
|
|
EP3732186A1
(de)
|
2017-12-29 |
2020-11-04 |
GlycoMimetics, Inc. |
Heterobifunktionale inhibitoren von e-selektin und galectin-3
|
|
JP7547345B2
(ja)
|
2018-12-27 |
2024-09-09 |
グリコミメティクス, インコーポレイテッド |
ガレクチン-3阻害性c-グリコシド
|
|
US11845771B2
(en)
|
2018-12-27 |
2023-12-19 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of E-selectin and galectin-3
|
|
WO2020229968A1
(en)
*
|
2019-05-10 |
2020-11-19 |
Alectos Therapeutics Inc. |
Non-lysosomal glucosylceramidase inhibitors and uses thereof
|