ES2669310T3 - Anticuerpos y otras moléculas que se unen con B7-H1 y PD-1 - Google Patents
Anticuerpos y otras moléculas que se unen con B7-H1 y PD-1 Download PDFInfo
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- ES2669310T3 ES2669310T3 ES12774724.4T ES12774724T ES2669310T3 ES 2669310 T3 ES2669310 T3 ES 2669310T3 ES 12774724 T ES12774724 T ES 12774724T ES 2669310 T3 ES2669310 T3 ES 2669310T3
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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Landscapes
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| US201161477414P | 2011-04-20 | 2011-04-20 | |
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| PCT/US2012/034223 WO2012145493A1 (en) | 2011-04-20 | 2012-04-19 | Antibodies and other molecules that bind b7-h1 and pd-1 |
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| EP3153526B1 (en) | 2008-01-31 | 2020-09-23 | INSERM - Institut National de la Santé et de la Recherche Médicale | Antibodies against human cd39 and use thereof for inhibiting t regulatory cells activity |
| TW202442680A (zh) | 2008-12-09 | 2024-11-01 | 美商建南德克公司 | 抗pd-l1抗體及其於增進t細胞功能之用途 |
| CA2802344C (en) * | 2010-06-18 | 2023-06-13 | The Brigham And Women's Hospital, Inc. | Bi-specific antibodies against tim-3 and pd-1 for immunotherapy in chronic immune conditions |
| PT3409278T (pt) | 2011-07-21 | 2020-12-18 | Sumitomo Dainippon Pharma Oncology Inc | Inibidores de proteína cinase heterocíclicos |
| EA037351B8 (ru) | 2012-05-15 | 2021-04-29 | Бристол-Майерс Сквибб Компани | Способ лечения злокачественных опухолей с использованием комбинации антител против pd-1 и ctla-4 |
| CN103566377A (zh) | 2012-07-18 | 2014-02-12 | 上海博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| EP2904011B1 (en) | 2012-10-02 | 2017-08-23 | Bristol-Myers Squibb Company | Combination of anti-kir antibodies and anti-pd-1 antibodies to treat cancer |
| AU2013361231A1 (en) * | 2012-12-19 | 2015-06-04 | Amplimmune, Inc. | B7-H4 specific antibodies, and compositions and methods of use thereof |
| MX2015008117A (es) * | 2012-12-21 | 2016-03-31 | Amplimmune Inc | Anticuerpos anti-h7cr. |
| US9657082B2 (en) | 2013-01-31 | 2017-05-23 | Thomas Jefferson University | PD-L1 and PD-L2-based fusion proteins and uses thereof |
| CA2901269C (en) | 2013-03-06 | 2022-01-18 | Astrazeneca Ab | Quinazoline inhibitors of activating mutant forms of epidermal growth factor receptor |
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| WO2014194293A1 (en) * | 2013-05-30 | 2014-12-04 | Amplimmune, Inc. | Improved methods for the selection of patients for pd-1 or b7-h4 targeted therapies, and combination therapies thereof |
| WO2014209804A1 (en) * | 2013-06-24 | 2014-12-31 | Biomed Valley Discoveries, Inc. | Bispecific antibodies |
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| HUE046964T2 (hu) | 2013-08-08 | 2020-04-28 | Cytune Pharma | Kombinált gyógyászati készítmény |
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| TWI680138B (zh) | 2014-01-23 | 2019-12-21 | 美商再生元醫藥公司 | 抗ｐｄ-ｌ１之人類抗體 |
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| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| US20170088626A1 (en) | 2014-03-05 | 2017-03-30 | Bristol-Myers Squibb Company | Treatment of renal cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent |
| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US9394365B1 (en) | 2014-03-12 | 2016-07-19 | Yeda Research And Development Co., Ltd | Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease |
| KR102248804B1 (ko) | 2014-03-12 | 2021-05-11 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | Cns의 질환 및 손상을 치료하기 위한 전신적 조절 t 세포 수준 또는 활성의 감소 |
| KR102442436B1 (ko) | 2014-03-14 | 2022-09-15 | 노파르티스 아게 | Lag-3에 대한 항체 분자 및 그의 용도 |
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| PT3151921T (pt) | 2014-06-06 | 2019-11-21 | Bristol Myers Squibb Co | Anticorpos contra recetor do fator de necrose tumoral induzido por glicocorticoide e utilizações dos mesmos |
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| ES2916923T3 (es) | 2014-07-11 | 2022-07-06 | Ventana Med Syst Inc | Anticuerpos anti-PD-L1 y usos diagnósticos de los mismos |
| BR122020025583B1 (pt) | 2014-07-22 | 2023-12-05 | Cb Therapeutics, Inc | Anticorpo isolado ou fragmento do mesmo que liga a pd-1, uso deste, composição, polinucleotídeo isolado e vetor de expressão |
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| PL3177644T3 (pl) | 2014-08-05 | 2021-06-14 | MabQuest SA | Immunologiczne reagenty wiążące do PD-1 |
| PL3177640T3 (pl) * | 2014-08-08 | 2020-11-02 | The Board Of Trustees Of The Leland Stanford Junior University | Charakteryzujące się wysokim powinowactwem środki terapeutyczne naśladujące PD-11 i sposoby ich wykorzystania |
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-
2012
- 2012-04-19 PT PT127747244T patent/PT2699264T/pt unknown
- 2012-04-19 HR HRP20180893TT patent/HRP20180893T1/hr unknown
- 2012-04-19 US US14/111,402 patent/US9205148B2/en not_active Expired - Fee Related
- 2012-04-19 DK DK12774724.4T patent/DK2699264T3/en active
- 2012-04-19 ES ES12774724.4T patent/ES2669310T3/es active Active
- 2012-04-19 EP EP12774724.4A patent/EP2699264B1/en active Active
- 2012-04-19 RS RS20180683A patent/RS57324B1/sr unknown
- 2012-04-19 PL PL12774724T patent/PL2699264T3/pl unknown
- 2012-04-19 CA CA2833636A patent/CA2833636A1/en not_active Abandoned
- 2012-04-19 WO PCT/US2012/034223 patent/WO2012145493A1/en not_active Ceased
- 2012-04-19 RU RU2013151455A patent/RU2625034C2/ru not_active IP Right Cessation
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- 2012-04-19 EP EP18161596.4A patent/EP3403672A1/en not_active Withdrawn
- 2012-04-19 SI SI201231320T patent/SI2699264T1/en unknown
- 2012-04-19 SM SM20180294T patent/SMT201800294T1/it unknown
- 2012-04-19 HU HUE12774724A patent/HUE037651T2/hu unknown
- 2012-04-19 JP JP2014506544A patent/JP6072771B2/ja not_active Expired - Fee Related
- 2012-04-19 MX MX2013012088A patent/MX338353B/es active IP Right Grant
- 2012-04-19 LT LTEP12774724.4T patent/LT2699264T/lt unknown
- 2012-04-19 KR KR1020137030691A patent/KR101970025B1/ko not_active Expired - Fee Related
- 2012-04-19 AU AU2012245477A patent/AU2012245477C1/en not_active Ceased
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2015
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-
2016
- 2016-12-28 JP JP2016254558A patent/JP2017101042A/ja active Pending
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2018
- 2018-06-13 CY CY181100615T patent/CY1120626T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL2699264T3 (pl) | 2018-08-31 |
| RU2625034C2 (ru) | 2017-07-11 |
| EP2699264A1 (en) | 2014-02-26 |
| US9205148B2 (en) | 2015-12-08 |
| RU2013151455A (ru) | 2015-05-27 |
| CN103608040B (zh) | 2017-03-01 |
| WO2012145493A1 (en) | 2012-10-26 |
| LT2699264T (lt) | 2018-07-10 |
| EP2699264B1 (en) | 2018-03-14 |
| CY1120626T1 (el) | 2019-12-11 |
| KR20140048121A (ko) | 2014-04-23 |
| HRP20180893T1 (hr) | 2018-07-27 |
| EP3403672A1 (en) | 2018-11-21 |
| AU2012245477B2 (en) | 2017-03-23 |
| AU2012245477C1 (en) | 2017-06-15 |
| JP2017101042A (ja) | 2017-06-08 |
| JP6072771B2 (ja) | 2017-02-01 |
| SMT201800294T1 (it) | 2018-07-17 |
| EP2699264A4 (en) | 2014-10-08 |
| RS57324B1 (sr) | 2018-08-31 |
| AU2012245477A1 (en) | 2013-10-31 |
| JP2014523401A (ja) | 2014-09-11 |
| CA2833636A1 (en) | 2012-10-26 |
| US20140044738A1 (en) | 2014-02-13 |
| US20160130348A1 (en) | 2016-05-12 |
| MX338353B (es) | 2016-04-13 |
| PT2699264T (pt) | 2018-05-23 |
| HUE037651T2 (hu) | 2018-09-28 |
| CN103608040A (zh) | 2014-02-26 |
| SI2699264T1 (en) | 2018-08-31 |
| DK2699264T3 (en) | 2018-06-25 |
| MX2013012088A (es) | 2014-04-30 |
| KR101970025B1 (ko) | 2019-04-17 |
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