EA201691872A1 - Гетероциклические соединения для применения в лечении pi3k-гамма-опосредованных расстройств - Google Patents

Гетероциклические соединения для применения в лечении pi3k-гамма-опосредованных расстройств

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Publication number
EA201691872A1
EA201691872A1 EA201691872A EA201691872A EA201691872A1 EA 201691872 A1 EA201691872 A1 EA 201691872A1 EA 201691872 A EA201691872 A EA 201691872A EA 201691872 A EA201691872 A EA 201691872A EA 201691872 A1 EA201691872 A1 EA 201691872A1
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EA
Eurasian Patent Office
Prior art keywords
pi3k
gamma
treatment
application
heterocyclic compounds
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EA201691872A
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English (en)
Inventor
Джеффри Л. Куток
Дэвид Дж. Уинклер
Вито Дж. Паломбелла
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Инфинити Фармасьютикалз, Инк.
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Application filed by Инфинити Фармасьютикалз, Инк. filed Critical Инфинити Фармасьютикалз, Инк.
Publication of EA201691872A1 publication Critical patent/EA201691872A1/ru

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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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Abstract

В настоящем документе описаны соединения и фармацевтические композиции, которые модулируют активность киназы, включая активность киназы PI3, и соединения, фармацевтические композиции и способы лечения заболеваний и состояний, ассоциированных с активностью киназы, включая активность киназы PI3.
EA201691872A 2014-03-19 2015-03-18 Гетероциклические соединения для применения в лечении pi3k-гамма-опосредованных расстройств EA201691872A1 (ru)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201461955717P 2014-03-19 2014-03-19
US201461980484P 2014-04-16 2014-04-16
US201462000923P 2014-05-20 2014-05-20
US201462033008P 2014-08-04 2014-08-04
US201462059766P 2014-10-03 2014-10-03
US201462075173P 2014-11-04 2014-11-04
US201562101980P 2015-01-09 2015-01-09
PCT/US2015/021200 WO2015143012A1 (en) 2014-03-19 2015-03-18 Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders

Publications (1)

Publication Number Publication Date
EA201691872A1 true EA201691872A1 (ru) 2017-04-28

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EA201691872A EA201691872A1 (ru) 2014-03-19 2015-03-18 Гетероциклические соединения для применения в лечении pi3k-гамма-опосредованных расстройств

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US (4) US9775844B2 (ru)
EP (2) EP3119397B1 (ru)
JP (1) JP6701088B2 (ru)
CN (3) CN113620958A (ru)
AU (1) AU2015231413B2 (ru)
CA (1) CA2943075C (ru)
DK (1) DK3119397T3 (ru)
EA (1) EA201691872A1 (ru)
ES (1) ES2913486T3 (ru)
IL (1) IL247841B (ru)
MX (1) MX2016012021A (ru)
NZ (1) NZ724368A (ru)
PH (1) PH12016501809A1 (ru)
PT (1) PT3119397T (ru)
SG (2) SG10201808053XA (ru)
WO (1) WO2015143012A1 (ru)

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