PT1144411E - Compostos espiro anti-histaminicos - Google Patents

Compostos espiro anti-histaminicos

Info

Publication number
PT1144411E
PT1144411E PT99964625T PT99964625T PT1144411E PT 1144411 E PT1144411 E PT 1144411E PT 99964625 T PT99964625 T PT 99964625T PT 99964625 T PT99964625 T PT 99964625T PT 1144411 E PT1144411 E PT 1144411E
Authority
PT
Portugal
Prior art keywords
spiro compounds
antihistaminic
antihistaminic spiro
compounds
spiro
Prior art date
Application number
PT99964625T
Other languages
English (en)
Inventor
Joseph Elisabeth Leenaerts
Frans Eduard Janssens
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT1144411E publication Critical patent/PT1144411E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/20Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Dental Preparations (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT99964625T 1998-12-19 1999-12-15 Compostos espiro anti-histaminicos PT1144411E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98204347 1998-12-19
PCT/EP1999/010176 WO2000037470A1 (en) 1998-12-19 1999-12-15 Antihistaminic spiro compounds

Publications (1)

Publication Number Publication Date
PT1144411E true PT1144411E (pt) 2005-09-30

Family

ID=8234498

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99964625T PT1144411E (pt) 1998-12-19 1999-12-15 Compostos espiro anti-histaminicos

Country Status (37)

Country Link
US (2) US7148214B1 (pt)
EP (1) EP1144411B1 (pt)
JP (1) JP4601175B2 (pt)
KR (1) KR100598725B1 (pt)
CN (1) CN1258533C (pt)
AR (1) AR021888A1 (pt)
AT (1) ATE294178T1 (pt)
AU (1) AU764820C (pt)
BG (1) BG65133B1 (pt)
BR (1) BR9916371A (pt)
CA (1) CA2355939C (pt)
CO (1) CO5140116A1 (pt)
CZ (1) CZ301953B6 (pt)
DE (1) DE69925036T2 (pt)
DK (1) DK1144411T3 (pt)
EA (1) EA004500B1 (pt)
EE (1) EE04917B1 (pt)
EG (1) EG24605A (pt)
ES (1) ES2242443T3 (pt)
HK (1) HK1043128B (pt)
HR (1) HRP20010453B1 (pt)
HU (1) HU229406B1 (pt)
ID (1) ID29268A (pt)
IL (1) IL143767A0 (pt)
MY (1) MY129663A (pt)
NO (1) NO318891B1 (pt)
NZ (1) NZ512870A (pt)
PL (1) PL196262B1 (pt)
PT (1) PT1144411E (pt)
SA (1) SA00210113B1 (pt)
SI (1) SI1144411T1 (pt)
SK (1) SK286158B6 (pt)
TR (1) TR200101711T2 (pt)
TW (1) TWI250981B (pt)
UA (1) UA74537C2 (pt)
WO (1) WO2000037470A1 (pt)
ZA (1) ZA200104977B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL367967A1 (en) * 2001-10-15 2005-03-07 Janssen Pharmaceutica N.V. Novel substituted 4-phenyl-4-[1h-imidazol-2-yl]-piperidine derivatives and their use as selective non-peptide delta opioid agonists
MXPA04003480A (es) * 2001-10-15 2004-07-30 Janssen Pharmaceutica Nv Derivados de 4-fenil-4-(1h-imidazol-2-il)-piperidina sustituida para la reduccion de la lesion isquemica.
WO2005110685A2 (en) * 2004-05-11 2005-11-24 Alliss George E Vegetation trimmer apparatus
DE602005014124D1 (de) * 2004-09-07 2009-06-04 Banyu Pharma Co Ltd Carbamoylsubstituiertes spiro-derivat
AU2009242279B2 (en) 2008-04-29 2012-08-30 Novartis Ag Spiro-indole derivatives for the treatment of parasitic diseases
US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
WO2015051241A1 (en) 2013-10-04 2015-04-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
CA2925944C (en) 2013-10-04 2023-01-10 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
EP4066834A1 (en) 2014-03-19 2022-10-05 Infinity Pharmaceuticals, Inc. Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders
JP6769963B2 (ja) 2014-08-29 2020-10-14 ティエエッセ ファルマ ソチエタ レスポンサビリタ リミタータ α−アミノ−β−カルボキシムコン酸セミアルデヒド脱炭酸酵素の阻害剤
WO2016054491A1 (en) 2014-10-03 2016-04-07 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
CN108349985A (zh) 2015-09-14 2018-07-31 无限药品股份有限公司 异喹啉酮的固体形式、其制备方法、包含其的组合物及其使用方法
WO2017088080A1 (es) 2015-11-25 2017-06-01 Natural Response S.A. Método para la obtención de saponinas a partir de plantas
US10759806B2 (en) 2016-03-17 2020-09-01 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as PI3K kinase inhibitors
US10919914B2 (en) 2016-06-08 2021-02-16 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
KR20240052354A (ko) 2022-10-14 2024-04-23 지이 일렉트리컬 엔지니어링 컴퍼니., 리미티드. 여과 장치
KR20240052355A (ko) 2022-10-14 2024-04-23 지이 일렉트리컬 엔지니어링 컴퍼니., 리미티드. 여과 장치용 커버
CN117624052B (zh) * 2024-01-26 2024-04-12 四川益能康生环保科技有限公司 一种用于捕集二氧化碳的离子液体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464380A (en) 1983-05-25 1984-08-07 Pfizer Inc. Imidazolidinedione derivatives
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
JPH089616B2 (ja) * 1990-10-10 1996-01-31 シェリング・コーポレーション 置換されたイミダゾベンズアゼピン類およびイミダゾピリドアゼピン類
IL101851A (en) 1991-06-13 1996-05-14 Janssen Pharmaceutica Nv History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them
US5106844A (en) * 1991-09-10 1992-04-21 Sterling Drug Inc. Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine antiarrhythmic agents
TW382017B (en) * 1995-12-27 2000-02-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives

Also Published As

Publication number Publication date
NO20012710D0 (no) 2001-06-01
ZA200104977B (en) 2002-06-18
TWI250981B (en) 2006-03-11
SA00210113B1 (ar) 2006-09-13
EA200100681A1 (ru) 2001-12-24
HRP20010453B1 (en) 2010-07-31
JP4601175B2 (ja) 2010-12-22
KR100598725B1 (ko) 2006-07-11
KR20010075655A (ko) 2001-08-09
ID29268A (id) 2001-08-16
BR9916371A (pt) 2001-09-18
SI1144411T1 (en) 2005-10-31
CZ20012069A3 (cs) 2002-02-13
HU229406B1 (en) 2013-12-30
HRP20010453A2 (en) 2002-06-30
EG24605A (en) 2010-01-10
JP2002533344A (ja) 2002-10-08
SK8142001A3 (en) 2002-04-04
CN1331694A (zh) 2002-01-16
HUP0104779A3 (en) 2003-12-29
DK1144411T3 (da) 2005-09-19
BG65133B1 (bg) 2007-03-30
PL196262B1 (pl) 2007-12-31
CA2355939A1 (en) 2000-06-29
WO2000037470A1 (en) 2000-06-29
HK1043128B (zh) 2007-01-19
EE04917B1 (et) 2007-10-15
DE69925036D1 (de) 2005-06-02
HK1043128A1 (en) 2002-09-06
HUP0104779A2 (hu) 2002-04-29
SK286158B6 (sk) 2008-04-07
UA74537C2 (uk) 2006-01-16
CN1258533C (zh) 2006-06-07
ATE294178T1 (de) 2005-05-15
EA004500B1 (ru) 2004-04-29
US7087595B2 (en) 2006-08-08
PL348295A1 (en) 2002-05-20
AU764820B2 (en) 2003-08-28
CZ301953B6 (cs) 2010-08-11
NO318891B1 (no) 2005-05-18
AU3041200A (en) 2000-07-12
CA2355939C (en) 2010-12-14
EP1144411A1 (en) 2001-10-17
BG105546A (en) 2001-12-29
EP1144411B1 (en) 2005-04-27
NZ512870A (en) 2003-11-28
WO2000037470A8 (en) 2000-08-24
ES2242443T3 (es) 2005-11-01
US20050026901A1 (en) 2005-02-03
AR021888A1 (es) 2002-08-07
DE69925036T2 (de) 2006-01-26
NO20012710L (no) 2001-06-01
TR200101711T2 (tr) 2001-12-21
IL143767A0 (en) 2002-04-21
EE200100328A (et) 2002-08-15
CO5140116A1 (es) 2002-03-22
MY129663A (en) 2007-04-30
US7148214B1 (en) 2006-12-12
AU764820C (en) 2004-11-18

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