DK1144411T3 - Antihistaminspiroforbindelser - Google Patents

Antihistaminspiroforbindelser

Info

Publication number
DK1144411T3
DK1144411T3 DK99964625T DK99964625T DK1144411T3 DK 1144411 T3 DK1144411 T3 DK 1144411T3 DK 99964625 T DK99964625 T DK 99964625T DK 99964625 T DK99964625 T DK 99964625T DK 1144411 T3 DK1144411 T3 DK 1144411T3
Authority
DK
Denmark
Prior art keywords
antihistamine
spiro compounds
spiro
compounds
antihistamine spiro
Prior art date
Application number
DK99964625T
Other languages
Danish (da)
English (en)
Inventor
Frans Eduard Janssens
Joseph Elisabeth Leenaerts
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK1144411T3 publication Critical patent/DK1144411T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/20Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/22Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Dental Preparations (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK99964625T 1998-12-19 1999-12-15 Antihistaminspiroforbindelser DK1144411T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98204347 1998-12-19
PCT/EP1999/010176 WO2000037470A1 (en) 1998-12-19 1999-12-15 Antihistaminic spiro compounds

Publications (1)

Publication Number Publication Date
DK1144411T3 true DK1144411T3 (da) 2005-09-19

Family

ID=8234498

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99964625T DK1144411T3 (da) 1998-12-19 1999-12-15 Antihistaminspiroforbindelser

Country Status (37)

Country Link
US (2) US7148214B1 (pt)
EP (1) EP1144411B1 (pt)
JP (1) JP4601175B2 (pt)
KR (1) KR100598725B1 (pt)
CN (1) CN1258533C (pt)
AR (1) AR021888A1 (pt)
AT (1) ATE294178T1 (pt)
AU (1) AU764820C (pt)
BG (1) BG65133B1 (pt)
BR (1) BR9916371A (pt)
CA (1) CA2355939C (pt)
CO (1) CO5140116A1 (pt)
CZ (1) CZ301953B6 (pt)
DE (1) DE69925036T2 (pt)
DK (1) DK1144411T3 (pt)
EA (1) EA004500B1 (pt)
EE (1) EE04917B1 (pt)
EG (1) EG24605A (pt)
ES (1) ES2242443T3 (pt)
HK (1) HK1043128B (pt)
HR (1) HRP20010453B1 (pt)
HU (1) HU229406B1 (pt)
ID (1) ID29268A (pt)
IL (1) IL143767A0 (pt)
MY (1) MY129663A (pt)
NO (1) NO318891B1 (pt)
NZ (1) NZ512870A (pt)
PL (1) PL196262B1 (pt)
PT (1) PT1144411E (pt)
SA (1) SA00210113B1 (pt)
SI (1) SI1144411T1 (pt)
SK (1) SK286158B6 (pt)
TR (1) TR200101711T2 (pt)
TW (1) TWI250981B (pt)
UA (1) UA74537C2 (pt)
WO (1) WO2000037470A1 (pt)
ZA (1) ZA200104977B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100898562B1 (ko) * 2001-10-15 2009-05-20 얀센 파마슈티카 엔.브이. 신규 치환된 4-페닐-4-[1h-이미다졸-2-일]-피페리딘유도체 및 선택적인 비펩타이드 델타 아편유사작용제로서의 그의 용도
DE60216310T2 (de) 2001-10-15 2007-06-21 Janssen Pharmaceutica N.V. Substituierte 4-phenyl-4-(1h-imidazol-2-yl)-piperidinderivate zur verringerung von ischämischer schädigung
WO2005110685A2 (en) * 2004-05-11 2005-11-24 Alliss George E Vegetation trimmer apparatus
WO2006028239A1 (ja) * 2004-09-07 2006-03-16 Banyu Pharmaceutical Co., Ltd. カルバモイル置換スピロ誘導体
KR101390081B1 (ko) 2008-04-29 2014-04-29 노파르티스 아게 기생충 질환의 치료를 위한 스피로-인돌 유도체
US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
EA201690713A1 (ru) 2013-10-04 2016-08-31 Инфинити Фармасьютикалз, Инк. Гетероциклические соединения и их применения
WO2015051241A1 (en) 2013-10-04 2015-04-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
DK3119397T3 (da) 2014-03-19 2022-03-28 Infinity Pharmaceuticals Inc Heterocykliske forbindelser til anvendelse i behandling af PI3K-gamma-medierede lidelser
EP3186242B1 (en) 2014-08-29 2021-10-06 Tes Pharma S.r.l. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
US9708348B2 (en) 2014-10-03 2017-07-18 Infinity Pharmaceuticals, Inc. Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof
AU2016322552B2 (en) 2015-09-14 2021-03-25 Infinity Pharmaceuticals, Inc. Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same
WO2017088080A1 (es) 2015-11-25 2017-06-01 Natural Response S.A. Método para la obtención de saponinas a partir de plantas
WO2017161116A1 (en) 2016-03-17 2017-09-21 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
WO2017214269A1 (en) 2016-06-08 2017-12-14 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
KR20240052355A (ko) 2022-10-14 2024-04-23 지이 일렉트리컬 엔지니어링 컴퍼니., 리미티드. 여과 장치용 커버
KR20240052354A (ko) 2022-10-14 2024-04-23 지이 일렉트리컬 엔지니어링 컴퍼니., 리미티드. 여과 장치
CN117624052B (zh) * 2024-01-26 2024-04-12 四川益能康生环保科技有限公司 一种用于捕集二氧化碳的离子液体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464380A (en) 1983-05-25 1984-08-07 Pfizer Inc. Imidazolidinedione derivatives
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
DE69110685T2 (de) * 1990-10-10 1995-11-09 Schering Corp Substituierte imidazobenzazepine und imidazopyridoazepine.
IL101851A (en) * 1991-06-13 1996-05-14 Janssen Pharmaceutica Nv History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition
IL101850A (en) * 1991-06-13 1996-01-31 Janssen Pharmaceutica Nv History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them
US5106844A (en) * 1991-09-10 1992-04-21 Sterling Drug Inc. Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine antiarrhythmic agents
TW382017B (en) 1995-12-27 2000-02-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives

Also Published As

Publication number Publication date
BR9916371A (pt) 2001-09-18
HU229406B1 (en) 2013-12-30
AU764820C (en) 2004-11-18
CA2355939A1 (en) 2000-06-29
JP4601175B2 (ja) 2010-12-22
HRP20010453B1 (en) 2010-07-31
TR200101711T2 (tr) 2001-12-21
HK1043128A1 (en) 2002-09-06
SK286158B6 (sk) 2008-04-07
US20050026901A1 (en) 2005-02-03
AR021888A1 (es) 2002-08-07
CA2355939C (en) 2010-12-14
NO318891B1 (no) 2005-05-18
TWI250981B (en) 2006-03-11
BG65133B1 (bg) 2007-03-30
SI1144411T1 (en) 2005-10-31
ID29268A (id) 2001-08-16
EE200100328A (et) 2002-08-15
HK1043128B (zh) 2007-01-19
NO20012710L (no) 2001-06-01
EA200100681A1 (ru) 2001-12-24
ATE294178T1 (de) 2005-05-15
SA00210113B1 (ar) 2006-09-13
PL196262B1 (pl) 2007-12-31
CN1258533C (zh) 2006-06-07
DE69925036D1 (de) 2005-06-02
EE04917B1 (et) 2007-10-15
NO20012710D0 (no) 2001-06-01
WO2000037470A8 (en) 2000-08-24
ZA200104977B (en) 2002-06-18
PL348295A1 (en) 2002-05-20
NZ512870A (en) 2003-11-28
AU764820B2 (en) 2003-08-28
UA74537C2 (uk) 2006-01-16
CZ20012069A3 (cs) 2002-02-13
CZ301953B6 (cs) 2010-08-11
WO2000037470A1 (en) 2000-06-29
AU3041200A (en) 2000-07-12
KR100598725B1 (ko) 2006-07-11
EA004500B1 (ru) 2004-04-29
BG105546A (en) 2001-12-29
HRP20010453A2 (en) 2002-06-30
EP1144411A1 (en) 2001-10-17
JP2002533344A (ja) 2002-10-08
US7087595B2 (en) 2006-08-08
ES2242443T3 (es) 2005-11-01
HUP0104779A2 (hu) 2002-04-29
IL143767A0 (en) 2002-04-21
DE69925036T2 (de) 2006-01-26
EP1144411B1 (en) 2005-04-27
KR20010075655A (ko) 2001-08-09
US7148214B1 (en) 2006-12-12
MY129663A (en) 2007-04-30
EG24605A (en) 2010-01-10
CO5140116A1 (es) 2002-03-22
CN1331694A (zh) 2002-01-16
SK8142001A3 (en) 2002-04-04
PT1144411E (pt) 2005-09-30
HUP0104779A3 (en) 2003-12-29

Similar Documents

Publication Publication Date Title
IS6267A (is) Ný spíróefnasambönd
EE200100502A (et) Ühendid
LTC1124961I2 (lt) Trombopoetino junginiai
ATE229954T1 (de) Betacarbolinverbindungen
ID28266A (id) Senyawa-senyawa amidin
EE200200224A (et) Uudsed ühendid
NO20011745L (no) Forbindelser
NO991821D0 (no) Substituerte tricykliske forbindelser
DK1144411T3 (da) Antihistaminspiroforbindelser
DE50009640D1 (de) Drehmaschine
NO20005006D0 (no) Kalsilytiske forbindelser
NO991823L (no) Substituerte tricykliske forbindelser
NO20013769D0 (no) Kalsilytiske forbindelser
NO20006662D0 (no) Fluorfenylresin-forbindelser
NO20020466L (no) Kalsilytiske forbindelser
NO20014262D0 (no) Tiazoloindolinon-forbindelser
ID29984A (id) Senyawa-senyawa bis-stirilbifenil
IDP000021790A (id) Senyawa-senyawa pirolum tersubstitusi
IDP000021799A (id) Senyawa-senyawa pirolum tersubstitusi
SE9802981D0 (sv) New tetracyclic compounds
SE9800626D0 (sv) Compounds
SE9804493D0 (sv) Novel compounds
SE9801989D0 (sv) Novel compounds
SE9804494D0 (sv) Novel compounds
SE9800458D0 (sv) Novel compounds