NO991823L - Substituerte tricykliske forbindelser - Google Patents

Substituerte tricykliske forbindelser

Info

Publication number
NO991823L
NO991823L NO991823A NO991823A NO991823L NO 991823 L NO991823 L NO 991823L NO 991823 A NO991823 A NO 991823A NO 991823 A NO991823 A NO 991823A NO 991823 L NO991823 L NO 991823L
Authority
NO
Norway
Prior art keywords
tricyclic compounds
substituted tricyclic
substituted
compounds
tricyclic
Prior art date
Application number
NO991823A
Other languages
English (en)
Other versions
NO991823D0 (no
Inventor
Nicholas James Bach
Jolie Anne Bastian
Douglas Wade Beight
Michael Dean Kinnick
Michael John Martinelli
Edward David Mihelich
John Michael Morin Jr
Daniel Jon Sall
Jason Scott Sawyer
Edward C R Smith
Tulio Suarez
Qiuping Wang
Thomas Michael Wilson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO991823D0 publication Critical patent/NO991823D0/no
Publication of NO991823L publication Critical patent/NO991823L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO991823A 1998-04-17 1999-04-16 Substituerte tricykliske forbindelser NO991823L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6216598A 1998-04-17 1998-04-17

Publications (2)

Publication Number Publication Date
NO991823D0 NO991823D0 (no) 1999-04-16
NO991823L true NO991823L (no) 1999-10-18

Family

ID=22040624

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991823A NO991823L (no) 1998-04-17 1999-04-16 Substituerte tricykliske forbindelser

Country Status (27)

Country Link
EP (2) EP0950661B1 (no)
JP (1) JP4435325B2 (no)
KR (1) KR19990083234A (no)
CN (1) CN1235968A (no)
AR (1) AR018185A1 (no)
AT (2) ATE259818T1 (no)
AU (1) AU757454B2 (no)
BR (1) BR9901275A (no)
CA (1) CA2269256A1 (no)
CO (1) CO5080728A1 (no)
CZ (1) CZ137199A3 (no)
DE (2) DE69914951T2 (no)
EA (1) EA003129B1 (no)
ES (2) ES2213668T3 (no)
HU (1) HUP9901219A1 (no)
ID (1) ID23219A (no)
IL (1) IL129484A0 (no)
NO (1) NO991823L (no)
NZ (1) NZ335252A (no)
PE (1) PE20000472A1 (no)
PL (1) PL332564A1 (no)
SG (1) SG106035A1 (no)
SV (1) SV1999000052A (no)
TR (1) TR199900842A2 (no)
TW (1) TW555760B (no)
YU (1) YU19099A (no)
ZA (1) ZA992773B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001513555A (ja) * 1997-08-28 2001-09-04 イーライ・リリー・アンド・カンパニー 非リウマチ様関節炎の処置方法
AU2001244635A1 (en) * 2000-03-30 2001-10-15 Yamanouchi Pharmaceutical Co..Ltd. Hydrazide derivatives
CN1450893A (zh) * 2000-07-14 2003-10-22 伊莱利利公司 治疗脓毒症的方法
ATE329905T1 (de) * 2000-12-18 2006-07-15 Lilly Co Eli Tetracyclische derivate als spla2 inhibitoren
ATE353876T1 (de) 2001-03-28 2007-03-15 Lilly Co Eli Substituierte carbazole als inhibitoren von spla2
US7109231B2 (en) 2001-08-09 2006-09-19 Eli Lilly And Company Cyclohept[b]indole derivatives
EP1423366A1 (en) 2001-08-09 2004-06-02 Eli Lilly And Company Cyclopenta b ! indole derivatives as spla2 inhibitors
US6992100B2 (en) 2001-12-06 2006-01-31 Eli Lilly And Company sPLA2 inhibitors
US7608626B2 (en) 2004-11-01 2009-10-27 Wyeth Substituted indolizines and derivatives as CNS agents
CN101945872B (zh) 2008-01-11 2014-07-23 阿尔巴尼分子研究公司 作为mch拮抗剂的(1-吖嗪酮)-取代的吡啶并吲哚
WO2011003021A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
WO2012088124A2 (en) 2010-12-21 2012-06-28 Albany Molecular Research, Inc. Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof
BR112013026283A8 (pt) * 2011-04-14 2018-01-30 Actelion Pharmaceuticals Ltd derivados de ácido 7-(heteroaril-amino)-6,7,8,9-tetrahidropirido[1,2-a]indol acético e seu uso como moduladores do receptor d2 de prostaglandina
PT2825542T (pt) 2012-03-16 2016-12-20 Vitae Pharmaceuticals Inc Modeladores do recetor x do fígado
US9006244B2 (en) 2012-03-16 2015-04-14 Vitae Pharmaceuticals, Inc. Liver X receptor modulators

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
MX9700511A (es) * 1994-07-21 1997-04-30 Lilly Co Eli Inhibidores de spla2 de indolizina.
BR9612347A (pt) * 1995-12-13 1999-07-13 Lilly Co Eli Naftil acetamidas como inibidores de spla2
TR199900956T2 (xx) * 1996-10-30 1999-07-21 Eli Lilly And Company S�bstit�e edilmi� trisiklik bile�imler.
EP1007056A1 (en) * 1997-09-26 2000-06-14 Eli Lilly And Company Method for the treatment of cystic fibrosis
WO1999025340A1 (en) * 1997-11-14 1999-05-27 Eli Lilly And Company Treatment for alzheimer's disease

Also Published As

Publication number Publication date
PL332564A1 (en) 1999-10-25
BR9901275A (pt) 2000-05-02
NZ335252A (en) 2000-11-24
SG106035A1 (en) 2004-09-30
EP1156050A2 (en) 2001-11-21
DE69912670D1 (de) 2003-12-18
ATE254128T1 (de) 2003-11-15
YU19099A (sh) 2001-09-28
EP1156050B1 (en) 2004-02-18
HU9901219D0 (en) 1999-06-28
ID23219A (id) 2000-03-30
PE20000472A1 (es) 2000-06-02
ATE259818T1 (de) 2004-03-15
EP0950661A1 (en) 1999-10-20
DE69914951T2 (de) 2004-12-23
TR199900842A2 (xx) 2000-09-21
CO5080728A1 (es) 2001-09-25
KR19990083234A (ko) 1999-11-25
HUP9901219A1 (hu) 2000-08-28
DE69912670T2 (de) 2004-08-12
JP4435325B2 (ja) 2010-03-17
NO991823D0 (no) 1999-04-16
EP0950661B1 (en) 2003-11-12
SV1999000052A (es) 2000-03-14
EA199900304A2 (ru) 1999-10-28
ES2213668T3 (es) 2004-09-01
DE69914951D1 (de) 2004-03-25
CN1235968A (zh) 1999-11-24
EA199900304A3 (ru) 2000-04-24
CA2269256A1 (en) 1999-10-17
AR018185A1 (es) 2001-10-31
AU2381899A (en) 1999-10-28
ZA992773B (en) 2002-07-16
EP1156050A3 (en) 2001-11-28
JPH11322745A (ja) 1999-11-24
ES2210979T3 (es) 2004-07-01
TW555760B (en) 2003-10-01
EA003129B1 (ru) 2003-02-27
AU757454B2 (en) 2003-02-20
CZ137199A3 (cs) 1999-11-17
IL129484A0 (en) 2000-02-29

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