IL129484A0 - Substituted tricyclics - Google Patents

Substituted tricyclics

Info

Publication number
IL129484A0
IL129484A0 IL12948499A IL12948499A IL129484A0 IL 129484 A0 IL129484 A0 IL 129484A0 IL 12948499 A IL12948499 A IL 12948499A IL 12948499 A IL12948499 A IL 12948499A IL 129484 A0 IL129484 A0 IL 129484A0
Authority
IL
Israel
Prior art keywords
substituted tricyclics
tricyclics
substituted
Prior art date
Application number
IL12948499A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL129484A0 publication Critical patent/IL129484A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
IL12948499A 1998-04-17 1999-04-15 Substituted tricyclics IL129484A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6216598A 1998-04-17 1998-04-17

Publications (1)

Publication Number Publication Date
IL129484A0 true IL129484A0 (en) 2000-02-29

Family

ID=22040624

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12948499A IL129484A0 (en) 1998-04-17 1999-04-15 Substituted tricyclics

Country Status (27)

Country Link
EP (2) EP1156050B1 (xx)
JP (1) JP4435325B2 (xx)
KR (1) KR19990083234A (xx)
CN (1) CN1235968A (xx)
AR (1) AR018185A1 (xx)
AT (2) ATE259818T1 (xx)
AU (1) AU757454B2 (xx)
BR (1) BR9901275A (xx)
CA (1) CA2269256A1 (xx)
CO (1) CO5080728A1 (xx)
CZ (1) CZ137199A3 (xx)
DE (2) DE69914951T2 (xx)
EA (1) EA003129B1 (xx)
ES (2) ES2213668T3 (xx)
HU (1) HUP9901219A1 (xx)
ID (1) ID23219A (xx)
IL (1) IL129484A0 (xx)
NO (1) NO991823L (xx)
NZ (1) NZ335252A (xx)
PE (1) PE20000472A1 (xx)
PL (1) PL332564A1 (xx)
SG (1) SG106035A1 (xx)
SV (1) SV1999000052A (xx)
TR (1) TR199900842A2 (xx)
TW (1) TW555760B (xx)
YU (1) YU19099A (xx)
ZA (1) ZA992773B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999009978A1 (en) * 1997-08-28 1999-03-04 Eli Lilly And Company Method for treatment of non-rheumatoid athritis
WO2001074817A1 (fr) * 2000-03-30 2001-10-11 Yamanouchi Pharmaceutical Co., Ltd. Derives d'hydrazide
CA2413582A1 (en) * 2000-07-14 2002-01-24 Eli Lilly And Company Use of a spla2 inhibitor for the treatment of sepsis
DE60120758T2 (de) * 2000-12-18 2007-05-16 Eli Lilly And Co., Indianapolis Tetracyclische derivate als spla2 inhibitoren
US6933313B2 (en) 2001-03-28 2005-08-23 Eli Lilly And Company Substituted carbazoles as inhibitors of sPLA2
JP2005527464A (ja) * 2001-08-09 2005-09-15 イーライ・リリー・アンド・カンパニー sPLA2インヒビターとしてのシクロヘプタBインドール誘導体
ATE312817T1 (de) 2001-08-09 2005-12-15 Lilly Co Eli Cyclohept'bö indolderivate als spla2-inhibitoren
US6992100B2 (en) 2001-12-06 2006-01-31 Eli Lilly And Company sPLA2 inhibitors
WO2006050007A2 (en) 2004-11-01 2006-05-11 Wyeth Substituted indolizines and derivatives as cns agents
ES2523580T3 (es) 2008-01-11 2014-11-27 Albany Molecular Research, Inc. Piridoindoles substituidos con (1-Azinona)
WO2011003021A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
US8993765B2 (en) 2010-12-21 2015-03-31 Albany Molecular Research, Inc. Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof
MX338516B (es) * 2011-04-14 2016-04-20 Actelion Pharmaceuticals Ltd Derivados de acido 7- (heteroaril-amino) -6, 7, 8, 9- tetrahidropirido[1,2-a] indol acetico y sus usos como modulador del receptor de prostaglandina.
PL2825541T3 (pl) 2012-03-16 2016-12-30 Modulatory receptora x wątroby
SI2825542T1 (sl) 2012-03-16 2017-01-31 Vitae Pharmaceutical Inc., Modulatorji jetrnega receptorja X

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
US6645976B1 (en) * 1994-07-21 2003-11-11 Eli Lilly And Company Indolizine SPLA2inhibitors
CA2240395A1 (en) * 1995-12-13 1997-06-19 David Kent Herron Naphthyl acetamides as spla2 inhibitors
IL129481A0 (en) * 1996-10-30 2000-02-29 Lilly Co Eli Substituted tricyclics
WO1999016453A1 (en) * 1997-09-26 1999-04-08 Eli Lilly And Company Method for the treatment of cystic fibrosis
JP2001522884A (ja) * 1997-11-14 2001-11-20 イーライ・リリー・アンド・カンパニー アルツハイマー病の処置方法

Also Published As

Publication number Publication date
EP1156050A3 (en) 2001-11-28
CZ137199A3 (cs) 1999-11-17
EP0950661B1 (en) 2003-11-12
ES2213668T3 (es) 2004-09-01
ES2210979T3 (es) 2004-07-01
AU757454B2 (en) 2003-02-20
EA199900304A2 (ru) 1999-10-28
ATE254128T1 (de) 2003-11-15
DE69914951D1 (de) 2004-03-25
DE69914951T2 (de) 2004-12-23
EP1156050A2 (en) 2001-11-21
ID23219A (id) 2000-03-30
NO991823L (no) 1999-10-18
NZ335252A (en) 2000-11-24
EP1156050B1 (en) 2004-02-18
BR9901275A (pt) 2000-05-02
JP4435325B2 (ja) 2010-03-17
AU2381899A (en) 1999-10-28
NO991823D0 (no) 1999-04-16
PL332564A1 (en) 1999-10-25
HU9901219D0 (en) 1999-06-28
ZA992773B (en) 2002-07-16
CA2269256A1 (en) 1999-10-17
PE20000472A1 (es) 2000-06-02
TW555760B (en) 2003-10-01
TR199900842A2 (xx) 2000-09-21
DE69912670T2 (de) 2004-08-12
HUP9901219A1 (hu) 2000-08-28
CO5080728A1 (es) 2001-09-25
SG106035A1 (en) 2004-09-30
YU19099A (sh) 2001-09-28
SV1999000052A (es) 2000-03-14
EA199900304A3 (ru) 2000-04-24
JPH11322745A (ja) 1999-11-24
CN1235968A (zh) 1999-11-24
KR19990083234A (ko) 1999-11-25
ATE259818T1 (de) 2004-03-15
EA003129B1 (ru) 2003-02-27
DE69912670D1 (de) 2003-12-18
EP0950661A1 (en) 1999-10-20
AR018185A1 (es) 2001-10-31

Similar Documents

Publication Publication Date Title
IL129483A0 (en) Substituted tricyclics
DE59912932D1 (en) Arylphenylsubstituierte cyclische ketoenole
DE59912303D1 (en) Arylphenylsubstituierte cyclische ketoenole
GB2342193B (en) Addition circuitry
PL341642A1 (en) Novel macrolydes
DE69904335D1 (en) Aminomethylcarbonsäurederivate
DE69835235D1 (en) Thermoplastische silikonelastomere
DE59903023D1 (en) Perorale wirkstoff-suspension
IL129481A0 (en) Substituted tricyclics
DE59914151D1 (en) Arylalkanoylpyridazine
SG106035A1 (en) Substituted tricyclics
EP1068213A4 (en) SILOXANES WITH AMINO-ORGANIC FUNCTIONAL GROUP
DE60042897D1 (en) Photovervielfacherröhre
DE59904407D1 (en) Chromanderivate
GB9816729D0 (en) Substituted cyclohexylaminopyrimidines
HK1039937A1 (zh) 取代的3-硫代氨基甲酰基吡唑類化合物
DE69821502D1 (en) Boroskop
PL347397A1 (en) Substituted 3-aryl-pyrazoles
DE59900495D1 (en) Multimetalloxidmassen
DE59900471D1 (en) Inchbremseinrichtung
PL345866A1 (en) Substituted cyclooctadepsipeptides
HK1039335A1 (zh) 取代的苯甲酰基環已二酮類化合物
DE69902586D1 (en) Expandierte ethylencopolymere
DE59905941D1 (en) Methoximinophenylessigsäureamide
DE59911094D1 (en) Tryptase-inhibitoren