DE295381C
(ru)
|
|
|
|
|
DE1470356A1
(de)
|
1964-01-15 |
1970-04-30 |
Thomae Gmbh Dr K |
Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
|
DE2050816A1
(de)
|
1970-10-16 |
1972-04-20 |
Dr. Karl Thomae Gmbh, 7950 Biberach |
Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
|
DE2050814A1
(de)
|
1970-10-16 |
1972-04-20 |
Dr. Karl Thomae Gmbh, 7950 Biberach |
Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen
|
DE1959402A1
(de)
|
1969-11-26 |
1971-06-03 |
Thomae Gmbh Dr K |
Neue 2-(5-Nitro-2-furyl)-4-oxi-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
|
DE2050815A1
(de)
|
1970-10-16 |
1972-04-20 |
Dr. Karl Thomae Gmbh, 7950 Biberach |
Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
|
DE1959403A1
(de)
|
1969-11-26 |
1971-06-03 |
Thomae Gmbh Dr K |
Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
|
DE2039662A1
(de)
|
1970-08-10 |
1972-02-17 |
Thomae Gmbh Dr K |
Neue 2-(5-Nitro-2-furyl)-vinyl-thieno-[3,2-d]pyrimide
|
JPS5659778A
(en)
|
1979-10-23 |
1981-05-23 |
Showa Denko Kk |
Dimethylthienopyrimidione derivative
|
IT1208123B
(it)
|
1983-04-19 |
1989-06-06 |
Fondedile Spa |
Colonna in conglomerato realizzata nel terreno in situ mediante immissione di materiali inerti durante la perforazione e contemporaneao successiva iniezione con opportuni leganti, procedimenti di esecuzione relativi
|
US5391485A
(en)
|
1985-08-06 |
1995-02-21 |
Immunex Corporation |
DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues
|
US4810643A
(en)
|
1985-08-23 |
1989-03-07 |
Kirin- Amgen Inc. |
Production of pluripotent granulocyte colony-stimulating factor
|
JPS63500636A
(ja)
|
1985-08-23 |
1988-03-10 |
麒麟麦酒株式会社 |
多分化能性顆粒球コロニー刺激因子をコードするdna
|
EP0276057B1
(en)
|
1987-01-21 |
1994-03-09 |
Merck & Co. Inc. |
Piperazinylpyrimidines as beta-adrenergic receptor blocking agents
|
US5102877A
(en)
|
1989-04-28 |
1992-04-07 |
Fujisawa Pharmaceutical Co., Ltd. |
1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
|
GB8912335D0
(en)
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
DE3922735A1
(de)
|
1989-07-11 |
1991-01-24 |
Hoechst Ag |
Aminopyrimidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als fungizide
|
DD295381A5
(de)
|
1990-10-01 |
1991-10-31 |
Karl-Marx-Universitaet Leipzig,De |
Verfahren zur herstellung von 8-amino-pyrazolo/4',3':4,5/thieno/3,2-d/pyrimidin-4-onen
|
US5202328A
(en)
|
1991-03-06 |
1993-04-13 |
Merck & Co., Inc. |
Substituted fused pyrimidinones
|
JP2972843B2
(ja)
|
1991-04-02 |
1999-11-08 |
工業技術院長 |
有機非線形光学材料
|
US5223501A
(en)
|
1991-05-10 |
1993-06-29 |
Merck & Co., Inc. |
Substituted pyrimidinones bearing acidic functional groups as angiotensin ii antagonists
|
TW201311B
(ru)
|
1991-06-17 |
1993-03-01 |
Hoffmann La Roche |
|
WO1993003040A1
(en)
|
1991-08-05 |
1993-02-18 |
Taisho Pharmaceutical Co., Ltd. |
Thienopyrimidin-4-one derivative
|
US5187168A
(en)
|
1991-10-24 |
1993-02-16 |
American Home Products Corporation |
Substituted quinazolines as angiotensin II antagonists
|
EP0696588A1
(en)
|
1992-07-17 |
1996-02-14 |
Rohm And Haas Company |
2-Arylpyrimidines and herbicidal use thereof
|
KR950703537A
(ko)
|
1992-10-16 |
1995-09-20 |
시모무라 도오루 |
피리미딘 유도체(pyrimidine derivative)
|
US5360352A
(en)
|
1992-12-24 |
1994-11-01 |
The Whitaker Corporation |
Wire retainer for current mode coupler
|
US5654307A
(en)
*
|
1994-01-25 |
1997-08-05 |
Warner-Lambert Company |
Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
|
US5654037A
(en)
*
|
1995-03-24 |
1997-08-05 |
Apx International |
Method of minimizing defects in painted composite material products
|
DE69708059T2
(de)
|
1996-02-07 |
2002-07-18 |
Janssen Pharmaceutica Nv |
Thiophenopyrimidine
|
DE69716810T2
(de)
|
1996-05-15 |
2003-02-27 |
Pfizer |
2,3-Disubstituierte-(5,6)-heteroarylkondensierte-pyrimidin-4-one
|
JP3870298B2
(ja)
|
1996-06-06 |
2007-01-17 |
株式会社大塚製薬工場 |
アミド誘導体
|
DE19632423A1
(de)
|
1996-08-12 |
1998-02-19 |
Merck Patent Gmbh |
Thienopyrimidine
|
DE19644228A1
(de)
*
|
1996-10-24 |
1998-04-30 |
Merck Patent Gmbh |
Thienopyrimidine
|
AU3709897A
(en)
|
1996-11-28 |
1998-06-22 |
Cheil Jedang Corporation |
Cathecol derivatives and a method for the preparation thereof and a pharmaceutical composition containing the same
|
HUP0002239A3
(en)
|
1997-05-08 |
2002-08-28 |
Agrevo Uk Ltd Hauxton |
The use of thienopyrimidine derivatives for combating fungi
|
DE69831446T2
(de)
|
1997-06-09 |
2006-06-14 |
Pfizer Prod Inc |
Chinazolin-4-on AMPA Antagonisten
|
US6323208B1
(en)
|
1997-09-05 |
2001-11-27 |
Pfizer Inc |
Atropisomers of 2,3-disubstituted-(5.6)-heteroaryl fused-pyrimidin-4-ones
|
IL125950A0
(en)
|
1997-09-05 |
1999-04-11 |
Pfizer Prod Inc |
Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
|
GB9719411D0
(en)
|
1997-09-12 |
1997-11-12 |
Ciba Geigy Ag |
New Pesticides
|
HUP0100287A3
(en)
|
1997-11-11 |
2003-04-28 |
Pfizer Prod Inc |
Thienopyrimidine and thienopyridine derivatives useful as anticancer agents
|
US20120046290A1
(en)
|
1997-12-22 |
2012-02-23 |
Jacques Dumas |
Inhibition of p38 kinase activity using substituted heterocyclic ureas
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
US6133271A
(en)
*
|
1998-11-19 |
2000-10-17 |
Cell Pathways, Inc. |
Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives
|
US6482948B1
(en)
|
1999-03-30 |
2002-11-19 |
Nippon Soda Co., Ltd. |
Thienopyrimidine compounds and salts thereof and process for the preparation of the same
|
GB9915437D0
(en)
|
1999-07-01 |
1999-09-01 |
Cerebrus Ltd |
Chemical compounds III
|
WO2001083456A1
(fr)
|
2000-04-27 |
2001-11-08 |
Yamanouchi Pharmaceutical Co., Ltd. |
Derives d'heteroaryle condenses
|
AR028782A1
(es)
|
2000-07-05 |
2003-05-21 |
Taisho Pharmaceutical Co Ltd |
Derivados heterociclicos tetrahidropiridino o piperidino
|
WO2002024683A1
(en)
*
|
2000-09-25 |
2002-03-28 |
Janssen Pharmaceutica N.V. |
Farnesyl transferase inhibiting 6-[(substituted phenyl)methyl]-quinoline and quinazoline derivatives
|
KR20030034232A
(ko)
|
2000-09-29 |
2003-05-01 |
닛뽕소다 가부시키가이샤 |
티에노피리미딘 화합물 및 그 염 및 제조방법
|
GB0100620D0
(en)
|
2001-01-10 |
2001-02-21 |
Vernalis Res Ltd |
Chemical cokpounds V
|
EP1254903B1
(en)
|
2001-04-20 |
2005-06-08 |
Ciba SC Holding AG |
4-Amino-2-(pyridin-2-yl)pyrimidine as microbicidal active substances
|
GB0124627D0
(en)
|
2001-10-15 |
2001-12-05 |
Smithkline Beecham Plc |
Novel compounds
|
JPWO2003035653A1
(ja)
|
2001-10-26 |
2005-02-10 |
日本曹達株式会社 |
ピリドチエノピリミジン化合物およびその塩
|
DE60218511T2
(de)
|
2001-10-26 |
2007-10-25 |
Istituto Di Richerche Di Biologia Molecolare P. Angeletti S.P.A. |
Dihydroxypyrimidin-carbonsäueramid-hemmer der hiv-integrase
|
DE60222302T2
(de)
|
2001-12-06 |
2008-05-29 |
Merck & Co., Inc. |
Inhibitoren von mitotischem kinesin
|
CA2472619A1
(en)
|
2002-01-10 |
2003-07-24 |
Bayer Corporation |
Fused pyrimidine derivates as rho-kinase inhibitors
|
WO2003106435A1
(en)
|
2002-06-18 |
2003-12-24 |
Sankyo Company, Limited |
Fused-ring pyrimidin-4(3h)-one derivatives, processes for the preparation and uses thereof
|
EP1553947A4
(en)
|
2002-10-21 |
2006-11-29 |
Bristol Myers Squibb Co |
QUINAZOLINONES AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS
|
WO2004065392A1
(en)
|
2003-01-24 |
2004-08-05 |
Smithkline Beecham Corporation |
Condensed pyridines and pyrimidines and their use as alk-5 receptor ligands
|
TW200508224A
(en)
|
2003-02-12 |
2005-03-01 |
Bristol Myers Squibb Co |
Cyclic derivatives as modulators of chemokine receptor activity
|
US7148226B2
(en)
|
2003-02-21 |
2006-12-12 |
Agouron Pharmaceuticals, Inc. |
Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
|
US7345046B2
(en)
|
2003-05-30 |
2008-03-18 |
Chiron Corporation |
Heteroaryl-fused pyrimidinyl compounds as anticancer agents
|
GB0315950D0
(en)
*
|
2003-06-11 |
2003-08-13 |
Xention Discovery Ltd |
Compounds
|
US8309562B2
(en)
|
2003-07-03 |
2012-11-13 |
Myrexis, Inc. |
Compounds and therapeutical use thereof
|
JP2006193426A
(ja)
|
2003-09-05 |
2006-07-27 |
Sankyo Co Ltd |
置換された縮環ピリミジン−4(3h)−オン化合物
|
BRPI0414238A
(pt)
|
2003-09-09 |
2006-10-31 |
Ono Pharmaceutical Co |
antagonistas de crf e compostos heterobicìclicos
|
DE10351436A1
(de)
*
|
2003-11-04 |
2005-06-09 |
Merck Patent Gmbh |
Verwendung von Thienopyrimidinen
|
US20050176738A1
(en)
|
2003-11-07 |
2005-08-11 |
Neurocrine Biosciences, Inc. |
Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto
|
JP4912145B2
(ja)
|
2004-02-26 |
2012-04-11 |
あすか製薬株式会社 |
ピリミジン誘導体
|
ATE464303T1
(de)
|
2004-04-28 |
2010-04-15 |
Vertex Pharma |
Als inhibitoren von rock und anderen proteinkinasen geeignete zusammensetzungen
|
ZA200609259B
(en)
|
2004-04-30 |
2008-07-30 |
Takeda Pharmaceutical |
Heterocyclic amide compound and use thereof as an mmp-13 inhibitor
|
US7683097B2
(en)
|
2004-05-27 |
2010-03-23 |
Propharmacon Inc. |
Topoisomerase inhibitors
|
UY28931A1
(es)
|
2004-06-03 |
2005-12-30 |
Bayer Pharmaceuticals Corp |
Derivados de pirrolotriazina utiles para tratar trastornos hiper-proliferativos y enfermedades asociadas con angiogenesis
|
US7598259B2
(en)
|
2004-06-15 |
2009-10-06 |
Schering Corporation |
mGluR1 antagonists as therapeutic agents
|
CA2583259C
(en)
|
2004-10-08 |
2011-08-02 |
Astellas Pharma Inc. |
Aromatic ring fused pyrimidine derivative
|
JP2008517896A
(ja)
|
2004-10-21 |
2008-05-29 |
ファイザー・インク |
C型肝炎ウイルスプロテアーゼの阻害剤並びにそれを用いた組成物及び治療
|
GB0423653D0
(en)
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
PT1838718E
(pt)
|
2005-01-10 |
2011-08-17 |
Pfizer |
Pirrolopirazoles, inibidores potentes da quinase
|
JP2009536608A
(ja)
|
2005-05-11 |
2009-10-15 |
メルク シャープ エンド ドーム リミテッド |
バニロイド−1受容体(vr1)の機能を調節する2,3−置換縮合二環式ピリミジン4−(3h)−オン
|
CA2612585A1
(en)
|
2005-06-27 |
2007-01-04 |
Amgen Inc. |
Anti-inflammatory aryl nitrile compounds
|
EP1928884B1
(en)
|
2005-09-23 |
2010-01-13 |
Equispharm Co., Ltd. |
5,6-dimethylthieno[2,3-di]pyrimidine derivatives, the preparation method thereof and the pharmaceutical composition comprising the same for anti-virus
|
WO2007056214A2
(en)
|
2005-11-02 |
2007-05-18 |
Cytovia, Inc |
N-alkyl-n-aryl-thienopyrimidin-r-amines and uses thereof
|
WO2007056215A2
(en)
|
2005-11-02 |
2007-05-18 |
Cytovia, Inc. |
N-aryl-thienopyrimidin-4-amines and the use thereof
|
PE20070855A1
(es)
|
2005-12-02 |
2007-10-14 |
Bayer Pharmaceuticals Corp |
Derivados de 4-amino-pirrolotriazina sustituida como inhibidores de quinasas
|
US20090170834A1
(en)
|
2005-12-22 |
2009-07-02 |
Prolexys Pharmaceuticals, Inc. |
Fused Pyrimidones and Thiopyrimidones, and Uses Thereof
|
EP1987042B1
(en)
|
2006-02-15 |
2015-01-21 |
Sanofi |
Novel amino alcohol-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
|
WO2007102679A1
(en)
*
|
2006-03-06 |
2007-09-13 |
Je Il Pharmaceutical Co., Ltd. |
Novel thienopyrimidine derivatives or pharmaceutically acceptable salts thereof, process for the preparation thereof and pharmaceutical composition comprising the same
|
US8173806B2
(en)
*
|
2006-03-17 |
2012-05-08 |
Mitsubishi Gas Chemical Company, Inc. |
Method for production of quinazolin-4-one derivative
|
TW200801012A
(en)
*
|
2006-04-26 |
2008-01-01 |
Piramed Ltd |
Phosphoinositide 3-kinase inhibitor compounds and methods of use
|
GB0608820D0
(en)
|
2006-05-04 |
2006-06-14 |
Piramed Ltd |
Pharmaceutical compounds
|
US8034834B2
(en)
|
2006-05-25 |
2011-10-11 |
Synta Pharmaceuticals Corp. |
Method for treating proliferative disorders with HSP90 inhibitors
|
AU2007258313A1
(en)
|
2006-06-12 |
2007-12-21 |
Vertex Pharmaceuticals Incorporated |
Thienopyrimidines useful as modulators of ion channels
|
FR2904318B1
(fr)
|
2006-07-27 |
2011-02-25 |
Scras |
Derives de pyrimidinone et leur utilisation comme medicament
|
WO2008016123A1
(fr)
|
2006-08-03 |
2008-02-07 |
Takeda Pharmaceutical Company Limited |
INHIBITEUR DE LA GSK-3β
|
WO2008020622A1
(fr)
|
2006-08-17 |
2008-02-21 |
Kyorin Pharmaceutical Co., Ltd. |
NOUVEAU COMPOSÉ DE THIÉNO[2,3-d]PYRIMIDINE
|
ES2528797T3
(es)
|
2006-08-21 |
2015-02-12 |
Genentech, Inc. |
Compuestos de aza-benzotiofenilo y métodos de uso
|
CN101583616B
(zh)
|
2006-08-21 |
2012-05-30 |
健泰科生物技术公司 |
氮杂苯并噻吩基化合物及使用方法
|
TW200819454A
(en)
|
2006-08-23 |
2008-05-01 |
Neurogen Corp |
Haloalkyl-substituted pyrimidinone derivatives
|
US20110144140A1
(en)
*
|
2006-09-07 |
2011-06-16 |
Eriksen Birgitte L |
Pyridinyl-pyrimidine derivatives useful as potassium channel modulating agents
|
EP2094704A4
(en)
|
2006-11-06 |
2010-12-08 |
Neurogen Corp |
CIS-CYCLOHEXYL SUBSTITUTED PYRIMIDINONE DERIVATIVES
|
JP5313909B2
(ja)
|
2006-11-13 |
2013-10-09 |
アイコス コーポレイション |
炎症性疾患および癌の処置のためのチエノピリミジノン
|
CA2670026A1
(en)
|
2006-11-20 |
2008-05-29 |
Alantos Pharmaceuticals Holding, Inc. |
Heterotricyclic metalloprotease inhibitors
|
US9487533B2
(en)
|
2006-12-07 |
2016-11-08 |
Genentech, Inc. |
Phosphoinositide 3-kinase inhibitor compounds and methods of use
|
WO2008082840A1
(en)
|
2006-12-29 |
2008-07-10 |
Abbott Laboratories |
Pim kinase inhibitors as cancer chemotherapeutics
|
WO2008082839A2
(en)
|
2006-12-29 |
2008-07-10 |
Abbott Laboratories |
Pim kinase inhibitors as cancer chemotherapeutics
|
US20090030196A1
(en)
|
2006-12-29 |
2009-01-29 |
Abbott Laboratories |
Pim kinase inhibitors as cancer chemotherapeutics
|
WO2008086053A1
(en)
|
2007-01-03 |
2008-07-17 |
Virobay, Inc. |
Hcv inhibitors
|
CL2008000252A1
(es)
|
2007-01-29 |
2008-03-14 |
Xenon Pharmaceuticals Inc |
Compuestos derivados de quinazolinona o pirimidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar enfermedades mediadas por los canales de calcio, tales como dolor, depresion, enfermedades cardiovasculares, respir
|
WO2008092862A1
(en)
|
2007-01-30 |
2008-08-07 |
Janssen Pharmaceutica N.V. |
Bicyclic derivatives as ep4 agonists
|
WO2008092860A1
(en)
|
2007-01-30 |
2008-08-07 |
Janssen Pharmaceutica N.V. |
Bicyclic derivatives as ep4 agonists
|
WO2008092861A1
(en)
|
2007-01-30 |
2008-08-07 |
Janssen Pharmaceutica N.V. |
Bicyclic derivatives as ep4 agonists
|
EP2134716A1
(en)
|
2007-04-18 |
2009-12-23 |
Bristol-Myers Squibb Company |
Pyrrolotriazine kinase inhibitors
|
US7906513B2
(en)
|
2007-04-26 |
2011-03-15 |
Enanta Pharmaceuticals, Inc. |
Hydrazide-containing hepatitis C serine protease inhibitors
|
US20080287449A1
(en)
|
2007-04-26 |
2008-11-20 |
Deqiang Niu |
Aza-tripeptide hepatitis c serine protease inhibitors
|
EP2014663A1
(de)
*
|
2007-07-12 |
2009-01-14 |
Bayer Schering Pharma AG |
Thienopyrimidylamine als Modulatoren des EP2-Rezeptors
|
US20090105124A1
(en)
|
2007-08-23 |
2009-04-23 |
Kalypsys, Inc. |
Heterocyclic modulators of tgr5
|
DE102007040243A1
(de)
|
2007-08-25 |
2009-02-26 |
Universität des Saarlandes |
17Beta-Hydroxysteriod-Dehydrogenase Typ1 Inhibitoren zur Behandlung hormonabhängiger Erkrankungen
|
DE102007051762A1
(de)
|
2007-10-30 |
2009-05-07 |
Bayer Healthcare Ag |
Substituierte Pyrrolotriazine und ihre Verwendung
|
US20110124649A1
(en)
|
2007-11-09 |
2011-05-26 |
The Johns Hopkins University |
Inhibitors of human methionine aminopeptidase 1 and methods of treating disorders
|
JP2011507910A
(ja)
|
2007-12-21 |
2011-03-10 |
ユニバーシティー オブ ロチェスター |
真核生物の寿命を変更するための方法
|
AR070127A1
(es)
|
2008-01-11 |
2010-03-17 |
Novartis Ag |
Pirrolo - pirimidinas y pirrolo -piridinas
|
CA2713108A1
(en)
|
2008-02-07 |
2009-08-13 |
Virobay, Inc. |
Inhibitors of cathepsin b
|
WO2009119880A1
(en)
|
2008-03-26 |
2009-10-01 |
Takeda Pharmaceutical Company Limited |
Substituted pyrazole derivatives and use thereof
|
WO2009121036A2
(en)
|
2008-03-27 |
2009-10-01 |
Neurogen Corporation |
Substituted aryl pyrimidinone derivatives
|
TWI389913B
(zh)
|
2008-09-08 |
2013-03-21 |
Lg Life Sciences Ltd |
并合雜環化合物
|
US20110257170A1
(en)
|
2008-10-03 |
2011-10-20 |
Merck Serono Sa |
4-morpholino-pyrido[3,2-d]pyrimidines
|
US20100093702A1
(en)
|
2008-10-13 |
2010-04-15 |
Barbay J Kent |
METHYLENE AMINES OF THIENO[2,3-d]PYRIMIDINE AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS
|
US20110135655A1
(en)
|
2009-01-13 |
2011-06-09 |
PHILADELPHIA HEALTH AND EDUCATION CORPORATION d/b/a Drexel University College of Medicine; |
Role of PI3K p110 delta Signaling in Retroviral Infection and Replication
|
JP5656976B2
(ja)
|
2009-04-29 |
2015-01-21 |
ローカス ファーマシューティカルズ インコーポレイテッド |
ピロロトリアジン化合物
|
WO2010138828A2
(en)
|
2009-05-29 |
2010-12-02 |
Abbott Laboratories |
Potassium channel modulators
|
AU2010276160A1
(en)
|
2009-07-21 |
2012-02-09 |
Gilead Calistoga Llc |
Treatment of liver disorders with PI3K inhibitors
|
EP2470012B1
(en)
|
2009-08-27 |
2014-11-05 |
Merck Sharp & Dohme Corp. |
Novel pyrrolidine derived beta 3 adrenergic receptor agonists
|
AU2011216404B2
(en)
|
2010-02-17 |
2016-04-07 |
Takeda Pharmaceutical Company Limited |
Heterocyclic compound
|
BR112012019635A2
(pt)
*
|
2010-02-22 |
2016-05-03 |
Hoffmann La Roche |
compostos inibidores de pirido[3,2-d] pirimidina pi3k delta e métodos de uso
|
US20120316184A1
(en)
|
2010-02-24 |
2012-12-13 |
Syngenta Crop Protection Llc |
Novel microbicides
|
WO2012004900A1
(en)
|
2010-07-09 |
2012-01-12 |
Aska Pharmaceutical Co., Ltd. |
Thienopyrimidine compounds
|
US20130317045A1
(en)
|
2010-09-01 |
2013-11-28 |
Ambit Biosciences Corporation |
Thienopyridine and thienopyrimidine compounds and methods of use thereof
|
WO2012037204A1
(en)
|
2010-09-14 |
2012-03-22 |
Exelixis, Inc. |
Inhibitors of pi3k-delta and methods of their use and manufacture
|
SG192826A1
(en)
|
2011-02-18 |
2013-09-30 |
Alexion Pharma Internat Sarl |
Methods for synthesizing molybdopterin precursor z derivatives
|
GB201105659D0
(en)
*
|
2011-04-01 |
2011-05-18 |
Xention Ltd |
Compounds
|
EP2508184A1
(en)
|
2011-04-06 |
2012-10-10 |
Æterna Zentaris GmbH |
Pyridopyrazine derivatives and their use
|
US9328075B2
(en)
|
2011-05-05 |
2016-05-03 |
St. Jude Children's Research Hospital |
Pyrimidinone compounds and methods for treating influenza
|
US9453021B2
(en)
|
2011-05-10 |
2016-09-27 |
Kyowa Hakko Kirin Co., Ltd. |
Pyrimidodiazepinone compound
|
MX349366B
(es)
|
2011-05-19 |
2017-07-26 |
Centro Nac De Investigaciones Oncologicas (Cnio) |
Compuestos novedosos.
|
US9260400B2
(en)
|
2011-05-24 |
2016-02-16 |
Universita' Degli Studi Di Bari “Aldo Moro” |
I-arylpiperazinic ligands of 5-HT7 receptor and use thereof
|
CN103797006B
(zh)
|
2011-07-13 |
2016-01-27 |
诺华股份有限公司 |
用作端锚聚合酶抑制剂的4-哌啶基化合物
|
WO2013032591A1
(en)
|
2011-08-29 |
2013-03-07 |
Infinity Pharmaceuticals Inc. |
Heterocyclic compounds and uses thereof
|
AR090037A1
(es)
*
|
2011-11-15 |
2014-10-15 |
Xention Ltd |
Derivados de tieno y/o furo-pirimidinas y piridinas inhibidores de los canales de potasio
|
EP3048106B1
(en)
*
|
2011-11-23 |
2019-11-06 |
Cancer Research Technology Limited |
Thienopyrimidine as inhibitors of atypical protein kinase c
|
UY34484A
(es)
|
2011-12-15 |
2013-07-31 |
Bayer Ip Gmbh |
Benzotienilo-pirrolotriazinas disustituidas y sus usos
|
US8940742B2
(en)
*
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
US9695133B2
(en)
|
2012-07-13 |
2017-07-04 |
The Trustees Of Columbia University In The City Of New York |
Quinazolinone-based oncogenic-RAS-selective lethal compounds and their use
|
US9566310B2
(en)
|
2012-09-10 |
2017-02-14 |
Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Reno |
Methods of treating muscular dystrophy
|
US20150291590A1
(en)
|
2012-09-17 |
2015-10-15 |
Cellixbio Private Limited |
Compositions and methods for the treatment of metabolic diseases
|
WO2014045039A2
(en)
|
2012-09-21 |
2014-03-27 |
Cancer Research Technology Limited |
Identification of protein kinase substrates
|
KR101446680B1
(ko)
|
2013-02-08 |
2014-10-07 |
한국과학기술연구원 |
mGluR1 길항제로 작용하는 사이에노피리미디논 유도체
|
UY35332A
(es)
|
2013-02-15 |
2014-11-28 |
Almirall Sa |
Derivados de pirrolotriazina como inhibidores de pi3k
|
EP2964654A4
(en)
|
2013-03-07 |
2016-08-10 |
Glaxosmithkline Llc |
THIEN [3,2-D] PYRIMIDIN-6-CARBOXAMIDE AND ANALOGUE AS SIRTUIN MODULATORS
|
US9050345B2
(en)
|
2013-03-11 |
2015-06-09 |
Bristol-Myers Squibb Company |
Pyrrolotriazines as potassium ion channel inhibitors
|
MX2015014387A
(es)
*
|
2013-04-12 |
2017-04-10 |
Asana Biosciences Llc |
Quinazolinas y azaquinazolinas como inhibidores duales de vias ras/raf/mek/erk y pi3k/akt/pten/mtor.
|
EP3019874B1
(en)
*
|
2013-07-09 |
2019-08-21 |
The Translational Genomics Research Institute |
Compositions and methods of screening for compounds that modulate activity at a tweak binding site on a crd of fn14
|
US9797882B2
(en)
*
|
2013-07-09 |
2017-10-24 |
The Translational Genomics Research Institute |
Method of screening for a compound for inhibitory activity of FN14-tweak interaction
|
EP3036229A1
(en)
|
2013-08-22 |
2016-06-29 |
F. Hoffmann-La Roche AG |
Alkynyl alcohols and methods of use
|
SG11201600028YA
(en)
|
2013-09-22 |
2016-02-26 |
Calitor Sciences Llc |
Substituted aminopyrimidine compounds and methods of use
|
US9745321B2
(en)
|
2013-09-30 |
2017-08-29 |
Shanghai Yingli Pharmaceutical Co., Ltd |
Fused pyrimidine compound, intermediate, preparation method therefor, and composition and application thereof
|
EP3052099B1
(en)
|
2013-10-03 |
2019-08-21 |
Merck Sharp & Dohme Corp. |
Novel pyrrolidine derived beta 3 adrenergic receptor agonists
|
BR112016008016B8
(pt)
|
2013-10-10 |
2023-09-26 |
Araxes Pharma Llc |
Compostos inibidores de kras g12c, composição farmacêutica compreendendo ditos compostos, métodos para regular a atividade e para preparar uma proteína mutante kras, hras ou nras g12c, método para inibir a proliferação de uma população de células e usos terapêuticos dos ditos compostos
|
TWI659021B
(zh)
*
|
2013-10-10 |
2019-05-11 |
亞瑞克西斯製藥公司 |
Kras g12c之抑制劑
|
WO2015148714A1
(en)
|
2014-03-25 |
2015-10-01 |
Duke University |
Heat shock protein 70 (hsp-70) receptor ligands
|
WO2015160192A1
(ko)
|
2014-04-15 |
2015-10-22 |
연세대학교 산학협력단 |
티에노피리미딘 유도체 또는 이의 약학적으로 허용가능한 염을 포함하는 백혈병 치료 및 예방용 약학 조성물
|
US10174032B2
(en)
*
|
2014-05-05 |
2019-01-08 |
Signalrx Pharmaceuticals, Inc. |
Heterocyclic compound classes for signaling modulation
|
MX2016014436A
(es)
|
2014-05-07 |
2017-01-23 |
Merck Patent Gmbh |
Derivados de heterociclil-butanamida.
|
EP3148986A4
(en)
|
2014-05-27 |
2018-01-10 |
Navigen, Inc. |
Arf6 inhibitors and methods of synthesis and use thereof
|
CN104230952B
(zh)
|
2014-08-16 |
2017-02-01 |
沈阳药科大学 |
含有嘧啶骨架的化合物及其制备方法和用途
|
JO3556B1
(ar)
|
2014-09-18 |
2020-07-05 |
Araxes Pharma Llc |
علاجات مدمجة لمعالجة السرطان
|
US10011600B2
(en)
|
2014-09-25 |
2018-07-03 |
Araxes Pharma Llc |
Methods and compositions for inhibition of Ras
|
CA2962917C
(en)
*
|
2014-10-29 |
2019-04-30 |
Dong-A St Co., Ltd. |
Novel pyridopyrimidinone compounds for modulating the catalytic activity of histone lysine demethylases (kdms)
|
EP3268490B1
(en)
|
2015-03-09 |
2020-07-08 |
Bayer Pharma Aktiengesellschaft |
Substituted 2,3-dihydroimidazo[1,2-c]quinazoline-containing combinations
|
AU2016244017B2
(en)
*
|
2015-04-03 |
2020-07-23 |
Nant Holdings Ip, Llc |
Compositions and methods of targeting mutant K-ras
|
EP3280708B1
(en)
|
2015-04-10 |
2021-09-01 |
Araxes Pharma LLC |
Substituted quinazoline compounds and methods of use thereof
|
US10421764B2
(en)
|
2015-04-24 |
2019-09-24 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Mutant KRas inhibitors
|
EP3294338A4
(en)
*
|
2015-05-13 |
2019-07-17 |
Memorial Sloan Kettering Cancer Center |
MACROPINOCYTOSIS USED IN THE IDENTIFICATION OF CANCER
|
WO2016200726A1
(en)
|
2015-06-08 |
2016-12-15 |
Texas Tech University System |
Inhibitors of mci-1 as drugs to overcome resistance to braf inhibitors and mek inhibitors
|
WO2016201257A2
(en)
|
2015-06-10 |
2016-12-15 |
The Johns Hopkins University |
Compositions and methods for identifying adp-ribosylated sites by mass spectrometry
|
MX2018000777A
(es)
|
2015-07-22 |
2018-03-23 |
Araxes Pharma Llc |
Compuestos de quinazolina sustituido y su uso como inhibidores de proteinas kras, hras y/o nras mutantes g12c.
|
WO2017015425A1
(en)
|
2015-07-23 |
2017-01-26 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
GB2560109B
(en)
|
2015-08-17 |
2020-05-20 |
Univ Holy Ghost Duquesne |
Thieno pyrimidine compounds and manufacture of the same
|
US20170057955A1
(en)
*
|
2015-08-26 |
2017-03-02 |
Dong-A Socio Holdings Co., Ltd. |
Pyridopyrimidinone Compounds for Modulating the Catalytic Activity of Histone Lysine Demethylases (KDMs)
|
WO2017040448A1
(en)
|
2015-08-31 |
2017-03-09 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
US10875842B2
(en)
|
2015-09-28 |
2020-12-29 |
Araxes Pharma Llc |
Inhibitors of KRAS G12C mutant proteins
|
WO2017058902A1
(en)
|
2015-09-28 |
2017-04-06 |
Araxes Pharma Llc |
Inhibitors of kras g12c mutant proteins
|
WO2017058805A1
(en)
|
2015-09-28 |
2017-04-06 |
Araxes Pharma Llc |
Inhibitors of kras g12c mutant proteins
|
WO2017058768A1
(en)
|
2015-09-28 |
2017-04-06 |
Araxes Pharma Llc |
Inhibitors of kras g12c mutant proteins
|
US10858343B2
(en)
|
2015-09-28 |
2020-12-08 |
Araxes Pharma Llc |
Inhibitors of KRAS G12C mutant proteins
|
WO2017059191A1
(en)
|
2015-09-30 |
2017-04-06 |
Quartet Medicine, Inc. |
Heteroaryl derivatives as sepiapterin reductase inhibitors
|
WO2017070256A2
(en)
|
2015-10-19 |
2017-04-27 |
Araxes Pharma Llc |
Method for screening inhibitors of ras
|
CA3005089A1
(en)
|
2015-11-16 |
2017-05-26 |
Araxes Pharma Llc |
2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof
|
SG11201804901WA
(en)
*
|
2015-12-22 |
2018-07-30 |
SHY Therapeutics LLC |
Compounds for the treatment of cancer and inflammatory disease
|
DK3436463T3
(da)
|
2016-03-28 |
2021-08-30 |
Takeda Pharmaceuticals Co |
Krystalline former af 2-[(2s)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1h-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3h)-on hemi-hydrat
|
EP3290412A1
(en)
|
2016-08-31 |
2018-03-07 |
Università degli Studi di Siena |
Hiv-1 nucleocapsid inhibitors
|
KR20180066985A
(ko)
|
2016-12-11 |
2018-06-20 |
연세대학교 산학협력단 |
티에노피리미딘 유도체 및 이의 용도
|
CA3066939A1
(en)
|
2017-06-21 |
2018-12-27 |
SHY Therapeutics LLC |
Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
|
US20220117968A1
(en)
|
2017-07-17 |
2022-04-21 |
Saint Louis University |
Thieno[2,3-d)pyrimidines and benzofuro(3,2-d)pyrimidines as antimicrobial agents
|
CN107721982B
(zh)
|
2017-10-16 |
2019-12-03 |
中山大学 |
一种抗肥胖症化合物及其制备方法和应用
|
WO2019105734A1
(en)
|
2017-11-28 |
2019-06-06 |
Bayer Consumer Care Ag |
Combinations of copanlisib
|
CN111094317B
(zh)
|
2017-12-29 |
2023-03-31 |
上海和誉生物医药科技有限公司 |
一种具有cd73抑制活性的膦酸衍生物、其制备方法和应用
|
WO2019180141A1
(en)
|
2018-03-23 |
2019-09-26 |
Bayer Aktiengesellschaft |
Combinations of rogaratinib
|