KR950703537A - 피리미딘 유도체(pyrimidine derivative) - Google Patents
피리미딘 유도체(pyrimidine derivative) Download PDFInfo
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- KR950703537A KR950703537A KR1019950701455A KR19950701455A KR950703537A KR 950703537 A KR950703537 A KR 950703537A KR 1019950701455 A KR1019950701455 A KR 1019950701455A KR 19950701455 A KR19950701455 A KR 19950701455A KR 950703537 A KR950703537 A KR 950703537A
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Abstract
본 발명은 제초활성 및 살진균 활성을 갖는 하기 일반식(I)의 피리미딘 유도체에 관한 것이다.:
[식중, R1및 R2는 각각 독립적으로 수소:알킬:알케닐:알키닐:페닐:시아노:COOR9:할로겐:OR10:SR11:OCOR12:아미노, Z1P=(=Z2)(Z3R13)(Z4R14), 또는 이들은 함께 옥소, 티옥소, 시클릭 케탈 또는 시클릭 티오케탈, =CR15R16:NR17:NNR18R19:NOR20:또는 하기로 구성된 군으로부터 선택된 스피로 고리를 형성하고;
R3및 R5는 각각 독립적으로 수소:할로겐:알킬:알케닐:알키닐:페닐:시클로알킬:S(O)mR21:NR22:R23:NR24NR25R26:OR27:시아노:COOR28:CONR29R30:PZ5(OR31)(OR32)이고:R4는 수소:할로겐:아미노:시아노:아미노:알킬:알케닐:알키닐:페닐:시클로알킬:COOR33:COR34:CONR35R36:OR37:S(O)pR38이지만, R4가 수소일 경우, R3및 R5는 상이하며 R4는 R3또는 R5및 피리미딘 고리와 결합하여 하기 일반식중의 하나로 나타내는 축합 고리를 형성하며
R6및 R7은 각각 독립적으로 수소:할로겐:알킬:알케닐:알키닐:페닐:시클로알킬:S(O)rR39:OR40:COOR41:CONR42R43:아미노:니트로 또는 시아노이고, 단, R6및 R7은 동시에 수소가 아니며, R8은 각각 동일하거나 상이할 수 있으며, 할로겐;알킬:알케닐:알키닐;페닐:시클로알킬:S(O)tR44:OR45:COOR46:CONR42R43:아미노:니트로 또는 시아노이고;n은 0, 1, 2 또는 3의 정수이며, 단, R1및 R2가 모두 수소일 경우 R4는 R3또는 R5및 피리미딘 고리와 결합하여 상술한 축합고리를 형성한다.]
Description
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Claims (8)
- 하기 일반식(I)의 피리미딘 유도체 및 그의 염;[식중, R1및 R2는 각각 독립적으로 수소;알킬;알케닐:알키닐:페닐:시아노:COOR9(식중, R9는 수소 또는 알킬이다):할로겐:OR10(식중, R10는 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):SR11(식중, R11는 수소, 알킬, 알케닐, 페닐 또는 시클로알킬이다):OCOR12(식중 R12는 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):아미노, Z1P=(=Z2)(Z3R13)(Z4R14)(식중, R13및 R14는 각각 독립적으로 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이고, Z1, Z2, Z3및 Z4는 각각 독립적으로 O 또는 S이다)이거나, 함께 옥소, 티옥소, 시클릭 케탈 또는 시클릭 티오케탈, =CR15R16(식중, R15및 R16은 각각 독립적으로 수소, 니트릴, 시아노, 알킬, 알케닐, 알키닐, 알킬카르보닐, 카르바모일, 카르복시, 알콕시카르보닐, 알케닐옥시카르보닐, 알키닐옥시카르보닐, 페닐, 알킬술포닐 또는 페닐술포닐이다), =NR17(식중, R17은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다), =NNR18(식중, R18및 R19는 각각 독립적으로 수소, 알킬, 알케닐, 알키닐, 페닐, 시클로알킬, 알콕시카르보닐 또는 카르복시이다), =NOR20(식중, R20은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다), 또는 하기로 구성된 군으로부터 선택된 스피로 고리를 형성하고;R3및 R5는 각각 독립적으로 수소:할로겐:알킬:알케닐:알키닐:페닐:시클로알킬:S(O)mR21(식중, R21은 수소, 알킬,알케닐, 알키닐, 페닐 또는 시클로알킬이고 m은 0,1 또는 2의 정수이다):NR22R23(식중, R22및 R23은 각각 독립적으로 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이거나 함께 고리를 형성할 수 있다):NR24NR25R26(식중, R24, R25및 R26은 각각 독립적으로 수소, 알킬, 알콕시카르보닐 또는 페닐이다):OR27(식중, R27은 수소,알킬,알케닐,페닐 또는 시클로알킬이다):시아노:COOR28(식중, R28은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):CONR29R30(식중, R29및 R30은 각각 독립적으로 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):CONR29R30(식중, R29및 R30은 각각 독립적으로 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):PZ5(OR31)(OR32)(식중, Z5는 O 또는 S이고, R31및 R32는 동일하거나 상이할 수 있으며 알킬 또는 페닐이다)이고:R4는 수소:할로겐:아미노:시아노:알킬:알케닐:알키닐:페닐:시클로알킬:COOR33(식중, R33은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):COR34(식중, R34은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):CONR35R36(식중, R35및 R36은 각각 독립적으로 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):OR37(식중, R37은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):S(O)pR38(식중, R38은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이고 p는 0,1 또는 2의 정수이다)이지만, R4가 수소일 경우, R3및 R5는 상이하며 R4는 R3또는 R5및 피리미딘 고리와 결합하여 하기 일반식중의 하나로 나타내는 축합 고리를 형성하며;[식중, A, B, C, D 및 E는 각각,O,S(O)q 또는를 나타내며, 나머지는를 나타낸다(상기에서, r1, r2및 r3는 각각 독립적으로 수소, 할로겐, 알킬, 페닐, 알킬카르보닐, 페닐카르보닐 또는 알콕시카르보닐이거나 인접 r1또는 r3와 결합하여 이중결합을 형성할 수 있고, q는 0, 1 또는 2의 정수이다)]; R6및 R7은 독립적으로 수소;할로겐;알킬;알케닐;알키닐;페닐;시클로알킬;S(O)rR39(식중, R39은 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이고 r은 0,1 또는 2의 정수이다):OR40(식중, R30은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):COOR41(식중, R41은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):CONR42R43(식중, R42및 R43은 각각 독립적으로 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):아미노:니트로 또는 시아노이고, 단, R6및 R7은 동시에 수소가 아니며; R8은 각각 동일하거나 상이할 수 있으며, 할로겐:알킬:알케닐:알키닐:페닐:시클로알킬:S(O)tR44(식중, R44은 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이고 t는 0, 1 또는 2의 정수이다):OR45(식중, R45은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):COOR46(R46은 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):CONR42R43(식중, R42및 R43은 각각 독립적으로 수소, 알킬, 알케닐, 알키닐, 페닐 또는 시클로알킬이다):아미노:니트로 또는 시아노이고; n은 0, 1, 2 또는 3의 정수이며, 단, R1및 R2가 모두 수소일 경우 R4는 R3또는 R5및 피리미딘 고리와 결합하여 상술한 축합고리를 형성한다.]
- 제1항에 있어서, 축합고리가 하기와 같은 피리미딘 유도체;[식중, R3,R5, r1, r2, r3및 q는 상기 정의한 바와 같다]
- 제1항 또는 제2항에 있어서, R1또는 R2가 히드록시 또는 할로겐이거나, R1및 R2가 함께 옥소기를 형성하는 피리미딘 유도체.
- 제1항 또는 제2항에 있어서, R15또는 R16이 카르바모일 또는 알콜시카르보닐인 피리미딘 유도체.
- 제1항 또는 제2항에 있어서, R17이 하기 기로 치환된 알킬인 피리미딘 유도체.
- 제1항 또는 제2항에 있어서, R3가 할로알킬 또는 측쇄 알킬인 피리미딘 유도체.
- 활성 성분으로서 하기 일반식(I)의 1종이상의 피리미딘 유도체를 함유하는 제조제;[식중, R1, R2, R3, R4, R5, R6, R7, R8및 n은 상기 정의한 바와 같다]
- 활성 성분으로서 하기 일반식(I)의 1종이상의 피리미딘 유도체를 함유하는 농경용 및 원예용 살진균제;[식중, R1, R2, R3, R4, R5, R6, R7, R8및 n은 상기 정의한 바와 같다]※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
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JP30462292 | 1992-10-16 | ||
JP92-304622 | 1992-10-16 | ||
JP15430393 | 1993-06-01 | ||
JP93-154303 | 1993-06-01 | ||
PCT/JP1993/001478 WO1994008975A1 (en) | 1992-10-16 | 1993-10-14 | Pyrimidine derivative |
Publications (1)
Publication Number | Publication Date |
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KR950703537A true KR950703537A (ko) | 1995-09-20 |
Family
ID=26482630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950701455A KR950703537A (ko) | 1992-10-16 | 1993-10-14 | 피리미딘 유도체(pyrimidine derivative) |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0665224A1 (ko) |
KR (1) | KR950703537A (ko) |
AU (1) | AU5161193A (ko) |
BR (1) | BR9307264A (ko) |
CA (1) | CA2147275A1 (ko) |
WO (1) | WO1994008975A1 (ko) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6268312B1 (en) | 1994-04-01 | 2001-07-31 | Shionogi & Co., Ltd. | Oxime derivative and bactericide containing the same as active ingredient |
CA2186947A1 (en) * | 1994-04-01 | 1995-10-12 | Kazuo Ueda | Oxime derivative and bactericide containing the same as active ingredients |
US6432964B1 (en) | 1997-05-08 | 2002-08-13 | Agrevo Uk Limited | Fungicides |
AU2003223049A1 (en) | 2002-03-13 | 2003-09-22 | Euro-Celtique S.A. | Aryl substituted pyrimidines and the use thereof |
AR044743A1 (es) * | 2002-09-26 | 2005-10-05 | Nihon Nohyaku Co Ltd | Herbicida, metodo de emplearlo, derivados de tienopirimidina sustituida,compuestos intermediarios, y procedimientos que se utilizan para producirlos, |
JP2004137270A (ja) * | 2002-09-26 | 2004-05-13 | Nippon Nohyaku Co Ltd | 新規除草剤、その使用方法、新規置換チエノピリミジン誘導体及びその中間体並びにそれらの製造方法 |
US8309562B2 (en) | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
US6818631B1 (en) | 2003-08-15 | 2004-11-16 | Nippon Soda Co. Ltd. | Fungicidal pyrimidine derivatives |
ZA200702380B (en) * | 2004-09-03 | 2008-09-25 | Celgene Corp | Substituted heterocyclic compounds and uses thereof |
CA2592900A1 (en) | 2005-01-03 | 2006-07-13 | Myriad Genetics Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
US8258145B2 (en) | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
ES2702362T3 (es) | 2007-01-31 | 2019-02-28 | Ym Biosciences Australia Pty | Compuestos a base de tiopirimidina y usos de los mismos |
CA2700524C (en) * | 2007-09-25 | 2017-08-01 | Actimis Pharmaceuticals, Inc. | Alkylthio pyrimidines as crth2 antagonists |
JP2012162460A (ja) * | 2009-05-27 | 2012-08-30 | Nippon Soda Co Ltd | 含窒素ヘテロアリール誘導体および農園芸用殺菌剤 |
WO2014001973A1 (en) | 2012-06-29 | 2014-01-03 | Pfizer Inc. | NOVEL 4-(SUBSTITUTED-AMINO)-7H-PYRROLO[2,3-d]PYRIMIDINES AS LRRK2 INHIBITORS |
US9695171B2 (en) | 2013-12-17 | 2017-07-04 | Pfizer Inc. | 3,4-disubstituted-1 H-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7H-pyrrolo[2,3-c]pyridazines as LRRK2 inhibitors |
US10131652B2 (en) | 2014-01-16 | 2018-11-20 | E. I. Du Pont De Nemours And Company | Pyrimidinyloxy benzene derivatives as herbicides |
AR101264A1 (es) * | 2014-07-25 | 2016-12-07 | Du Pont | Piridonas como herbicidas |
MX2017009792A (es) | 2015-03-18 | 2017-10-27 | Du Pont | Derivados de pirimidiniloxipiridina sustituidos como herbicidas. |
TWI828952B (zh) | 2015-06-05 | 2024-01-11 | 美商艾佛艾姆希公司 | 作為除草劑之嘧啶氧基苯衍生物 |
EP3322293B1 (en) | 2015-07-13 | 2021-05-19 | FMC Corporation | Aryloxypyrimidinyl ethers as herbicides |
EP3350178B1 (en) | 2015-09-14 | 2021-10-20 | Pfizer Inc. | Novel imidazo [4,5-c]quinoline and imidazo [4,5-c][1,5]naphthyridine derivatives as lrrk2 inhibitors |
SG11201804901WA (en) | 2015-12-22 | 2018-07-30 | SHY Therapeutics LLC | Compounds for the treatment of cancer and inflammatory disease |
RU2019138586A (ru) | 2017-05-02 | 2021-05-28 | Фмк Корпорейшн | Пиримидинилоксибензо-конденсированные соединения в качестве гербицидов |
SG11201911929XA (en) | 2017-06-21 | 2020-01-30 | SHY Therapeutics LLC | Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease |
EP4026833A1 (de) * | 2021-01-12 | 2022-07-13 | Bayer Aktiengesellschaft | Herbizid wirksame 2-(het)arylmethylpyrimidine |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3546212A (en) * | 1968-06-12 | 1970-12-08 | Hoffmann La Roche | Oxidation of benzodiazepines with ruthenium tetroxide |
GB8917222D0 (en) * | 1989-07-27 | 1989-09-13 | Schering Agrochemicals Ltd | Herbicides |
HU212435B (en) * | 1990-06-07 | 1996-06-28 | Sandoz Ag | Herbicidal compositions containing substituted phthalides and heterocyclic phthalides as active ingredient and process for preparation of their active ingredients. |
HU213178B (en) * | 1991-12-06 | 1997-03-28 | Sandoz Ag | Herbicid composition containing phthalide derivative as active ingredient, process for thereof and preparing the active ingredients |
JPH0649039A (ja) * | 1992-06-04 | 1994-02-22 | Nippon Soda Co Ltd | ピリミジン誘導体、除草剤および農園芸用殺菌剤 |
-
1993
- 1993-10-14 KR KR1019950701455A patent/KR950703537A/ko not_active Application Discontinuation
- 1993-10-14 BR BR9307264A patent/BR9307264A/pt not_active Application Discontinuation
- 1993-10-14 EP EP93922632A patent/EP0665224A1/en not_active Withdrawn
- 1993-10-14 WO PCT/JP1993/001478 patent/WO1994008975A1/ja not_active Application Discontinuation
- 1993-10-14 CA CA002147275A patent/CA2147275A1/en not_active Abandoned
- 1993-10-14 AU AU51611/93A patent/AU5161193A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU5161193A (en) | 1994-05-09 |
BR9307264A (pt) | 1999-05-11 |
WO1994008975A1 (en) | 1994-04-28 |
CA2147275A1 (en) | 1994-04-28 |
EP0665224A1 (en) | 1995-08-02 |
EP0665224A4 (en) | 1995-06-13 |
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