CN104769127A - 微胶囊组合物及方法 - Google Patents

微胶囊组合物及方法 Download PDF

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Publication number
CN104769127A
CN104769127A CN201380053555.6A CN201380053555A CN104769127A CN 104769127 A CN104769127 A CN 104769127A CN 201380053555 A CN201380053555 A CN 201380053555A CN 104769127 A CN104769127 A CN 104769127A
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Prior art keywords
microcapsules
dna
nucleic acid
composition
cases
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Pending
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CN201380053555.6A
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English (en)
Chinese (zh)
Inventor
本杰明·辛德森
瑟奇·萨克森诺夫
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10X Genomics Inc
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10X Genomics Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50101458&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN104769127(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 10X Genomics Inc filed Critical 10X Genomics Inc
Priority to CN202010761140.6A priority Critical patent/CN111748607B/zh
Priority to CN202110738748.1A priority patent/CN113528634A/zh
Priority to CN202210540740.9A priority patent/CN114891871A/zh
Publication of CN104769127A publication Critical patent/CN104769127A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52Containers specially adapted for storing or dispensing a reagent
    • B01L3/523Containers specially adapted for storing or dispensing a reagent with means for closing or opening
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1065Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0677Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2535/00Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
    • C12Q2535/122Massive parallel sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/159Microreactors, e.g. emulsion PCR or sequencing, droplet PCR, microcapsules, i.e. non-liquid containers with a range of different permeability's for different reaction components

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201380053555.6A 2012-08-14 2013-08-13 微胶囊组合物及方法 Pending CN104769127A (zh)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN202010761140.6A CN111748607B (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法
CN202110738748.1A CN113528634A (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法
CN202210540740.9A CN114891871A (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201261683192P 2012-08-14 2012-08-14
US61/683,192 2012-08-14
US201261737374P 2012-12-14 2012-12-14
US61/737,374 2012-12-14
US201361762435P 2013-02-08 2013-02-08
US61/762,435 2013-02-08
US201361800223P 2013-03-15 2013-03-15
US61/800,223 2013-03-15
US201361840403P 2013-06-27 2013-06-27
US61/840,403 2013-06-27
US201361844804P 2013-07-10 2013-07-10
US61/844,804 2013-07-10
PCT/US2013/054797 WO2014028537A1 (en) 2012-08-14 2013-08-13 Microcapsule compositions and methods

Related Child Applications (3)

Application Number Title Priority Date Filing Date
CN202010761140.6A Division CN111748607B (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法
CN202110738748.1A Division CN113528634A (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法
CN202210540740.9A Division CN114891871A (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法

Publications (1)

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CN104769127A true CN104769127A (zh) 2015-07-08

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CN202210540740.9A Pending CN114891871A (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法
CN202110738748.1A Pending CN113528634A (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法
CN202010761140.6A Active CN111748607B (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法
CN201380053555.6A Pending CN104769127A (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法

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CN202110738748.1A Pending CN113528634A (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法
CN202010761140.6A Active CN111748607B (zh) 2012-08-14 2013-08-13 微胶囊组合物及方法

Country Status (12)

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US (13) US20140155295A1 (enExample)
EP (3) EP2885418A4 (enExample)
JP (2) JP6367196B2 (enExample)
KR (1) KR102090851B1 (enExample)
CN (4) CN114891871A (enExample)
AU (5) AU2013302756C1 (enExample)
BR (1) BR112015003354A8 (enExample)
CA (2) CA3216609C (enExample)
IL (1) IL237156B (enExample)
IN (1) IN2015DN01126A (enExample)
MX (1) MX364957B (enExample)
WO (1) WO2014028537A1 (enExample)

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CN108070526A (zh) * 2015-11-19 2018-05-25 赛纳生物科技(北京)有限公司 一种核酸测序系统
CN108883031A (zh) * 2016-03-24 2018-11-23 生物辐射实验室股份有限公司 使用凝胶珠来控制液滴分散
CN111346562A (zh) * 2018-12-20 2020-06-30 恩德莱斯和豪瑟尔分析仪表两合公司 用于制备溶液的方法和系统
CN111542754A (zh) * 2017-12-29 2020-08-14 布林克公司 用于检测和/或定量样品中的分析物的微胶囊
CN114534806A (zh) * 2014-04-10 2022-05-27 10X基因组学有限公司 用于封装和分割试剂的流体装置、系统和方法及其应用
CN116905093A (zh) * 2023-06-07 2023-10-20 祥符实验室 一种dna数据库的长期保存方法及其应用
CN119184929A (zh) * 2024-10-10 2024-12-27 上海心玮医疗科技股份有限公司 一种快速治疗颅内血管狭窄的药物支架

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