|
US7605238B2
(en)
*
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
|
MXPA02001911A
(es)
*
|
1999-08-24 |
2003-07-21 |
Medarex Inc |
Anticuerpos ctla-4 humanos y sus usos.
|
|
PL356836A1
(en)
|
2000-02-10 |
2004-07-12 |
Abbott Laboratories |
Antibodies that bind human interleukin-18 and methods of making and using
|
|
EP1355666B1
(en)
|
2000-12-22 |
2012-06-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Use of repulsive guidance molecule (RGM) and its modulators
|
|
WO2002053596A2
(en)
|
2001-01-05 |
2002-07-11 |
Pfizer Inc. |
Antibodies to insulin-like growth factor i receptor
|
|
ATE420659T1
(de)
|
2001-04-26 |
2009-01-15 |
Biogen Idec Inc |
Criptoblockierende antikörper und deren verwendung
|
|
WO2002092017A2
(en)
|
2001-05-16 |
2002-11-21 |
Albert Einstein College Of Medicine Of Yeshiva University |
Human antipneumococcal antibodies from non-human animals
|
|
IL149701A0
(en)
*
|
2001-05-23 |
2002-11-10 |
Pfizer Prod Inc |
Use of anti-ctla-4 antibodies
|
|
DK2087908T3
(en)
*
|
2001-06-26 |
2018-07-23 |
Amgen Inc |
ANTIBODIES AGAINST OPGL
|
|
AU2006228095B2
(en)
*
|
2001-10-11 |
2010-11-04 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
AU2003220525A1
(en)
|
2002-03-29 |
2003-10-20 |
Abgenix, Inc. |
Human monoclonal antibodies to interleukin-5 and methods and compositions comprising same
|
|
US7452535B2
(en)
|
2002-04-12 |
2008-11-18 |
Medarex, Inc. |
Methods of treatment using CTLA-4 antibodies
|
|
AU2003260871A1
(en)
*
|
2002-09-30 |
2004-04-19 |
Pfizer Products Inc. |
Hybridomas producing high levels of human sequence antibody
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
US7465446B2
(en)
|
2003-05-30 |
2008-12-16 |
Medarex, Inc. |
Surrogate therapeutic endpoint for anti-CTLA4-based immunotherapy of disease
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
WO2005019270A2
(en)
*
|
2003-08-14 |
2005-03-03 |
Dyax Corp. |
Endotheliase-2 ligands
|
|
AR045563A1
(es)
*
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
US20050100965A1
(en)
|
2003-11-12 |
2005-05-12 |
Tariq Ghayur |
IL-18 binding proteins
|
|
OA13358A
(en)
|
2004-01-09 |
2007-04-13 |
Amgen Fremont Inc |
Antibodies to MAdCAM.
|
|
CN1964739A
(zh)
*
|
2004-03-26 |
2007-05-16 |
辉瑞产品公司 |
抗ctla－4抗体的用途
|
|
US7494779B2
(en)
|
2004-06-14 |
2009-02-24 |
Li-Te Chin |
Method for producing human antibodies to human CD152 with properties of agonist, antagonist, or inverse agonist
|
|
PL2287195T3
(pl)
|
2004-07-01 |
2019-10-31 |
Novo Nordisk As |
Przeciwciała pan-kir2dl receptora nk i ich zastosowanie w diagnostyce i terapii
|
|
JP2008506681A
(ja)
|
2004-07-16 |
2008-03-06 |
ファイザー・プロダクツ・インク |
抗ｉｇｆ−１ｒ抗体を用いる非血液性の悪性腫瘍の併用療法
|
|
WO2006056464A2
(en)
*
|
2004-11-26 |
2006-06-01 |
Pieris Ag |
Compound with affinity for the cytotoxic t lymphocyte-associated antigen (ctla-4)
|
|
BRPI0608855A2
(pt)
*
|
2005-03-08 |
2010-02-02 |
Pharmacia & Upjohn Co Llc |
composições de anticorpo anti - madcam processo para a preparação das mesmas e uso de anticorpo anti - madcam
|
|
AU2014240252B2
(en)
*
|
2005-03-08 |
2016-10-06 |
Pfizer Products Inc |
Anti-CTLA-4 Antibody Compositions
|
|
AU2012200203B2
(en)
*
|
2005-03-08 |
2014-07-03 |
Pfizer Products Inc. |
Anti-CTLA-4 Antibody Compositions
|
|
AU2006227879A1
(en)
*
|
2005-03-23 |
2006-09-28 |
Pfizer Products Inc. |
Therapy of prostate cancer with CTLA4 antibodies and hormonal therapy
|
|
JP2006265155A
(ja)
*
|
2005-03-23 |
2006-10-05 |
Link Genomics Kk |
癌の免疫療法
|
|
WO2006105021A2
(en)
|
2005-03-25 |
2006-10-05 |
Tolerrx, Inc. |
Gitr binding molecules and uses therefor
|
|
AP2007004243A0
(en)
|
2005-04-25 |
2007-12-31 |
Pfizer |
Antibodies to myostatin
|
|
GEP20115226B
(en)
|
2005-04-26 |
2011-06-10 |
Pfizer |
P-cadherin antibodies
|
|
US20090041783A1
(en)
|
2005-04-28 |
2009-02-12 |
Mochida Pharmaceutical Co., Ltd. |
Anti-platelet membrane glycoprotein vi monoclonal antibody
|
|
JP5224707B2
(ja)
*
|
2005-04-28 |
2013-07-03 |
持田製薬株式会社 |
抗血小板膜糖蛋白質ｖｉモノクローナル抗体
|
|
KR101498834B1
(ko)
|
2005-05-09 |
2015-03-05 |
오노 야꾸힝 고교 가부시키가이샤 |
예정 사멸 인자 1(ｐｄ-1)에 대한 인간 모노클로날 항체, 및 항-ｐｄ-1 항체를 단독 사용하거나 기타 면역 요법제와 병용한 암 치료 방법
|
|
EP3130350A1
(en)
|
2005-06-08 |
2017-02-15 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1)pathway
|
|
KR20080030656A
(ko)
*
|
2005-07-07 |
2008-04-04 |
콜레이 파마시티컬 그룹, 인코포레이티드 |
암 치료를 위한 항-ＣＴＬＡ-4 항체 및 ＣｐＧ-모티프-함유합성 올리고데옥시뉴클레오티드의 조합 요법
|
|
CN100443503C
(zh)
*
|
2005-07-18 |
2008-12-17 |
四川大学华西医院 |
人源化ctla-4单链抗体与人穿孔素通道形成肽p34的重组免疫毒素
|
|
CA2618482C
(en)
|
2005-08-19 |
2014-10-07 |
Abbott Laboratories |
Dual variable domain immunoglobin and uses thereof
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
EP2500355A3
(en)
|
2005-08-19 |
2012-10-24 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
KR101390127B1
(ko)
|
2005-09-07 |
2014-05-13 |
암젠 프레몬트 인코포레이티드 |
액티빈 수용체 유사 키나제-1에 대한 인간 모노클로날 항체
|
|
US7700567B2
(en)
|
2005-09-29 |
2010-04-20 |
Supergen, Inc. |
Oligonucleotide analogues incorporating 5-aza-cytosine therein
|
|
CN101277974A
(zh)
|
2005-09-30 |
2008-10-01 |
阿伯特有限及两合公司 |
排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途
|
|
WO2007056540A2
(en)
|
2005-11-08 |
2007-05-18 |
Medarex, Inc. |
Tnf-alpha blocker treatment for enterocolitis associated with immunostimulatory therapeutic antibody therapy
|
|
HRP20140240T4
(hr)
|
2005-11-30 |
2017-02-24 |
Abbvie Inc. |
Monoklonalna antitijela protiv amiloidnih beta proteina i njihova upotreba
|
|
EP1954718B1
(en)
|
2005-11-30 |
2014-09-03 |
AbbVie Inc. |
Anti-a globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies
|
|
CA2630157C
(en)
|
2005-12-07 |
2018-01-09 |
Medarex, Inc. |
Ctla-4 antibody dosage escalation regimens
|
|
EP1997887B1
(en)
|
2006-03-03 |
2013-09-04 |
Ono Pharmaceutical Co., Ltd. |
Multimer of extracellular domain of cell surface functional molecule
|
|
WO2007123737A2
(en)
|
2006-03-30 |
2007-11-01 |
University Of California |
Methods and compositions for localized secretion of anti-ctla-4 antibodies
|
|
US7919079B2
(en)
*
|
2006-03-31 |
2011-04-05 |
Biosante Pharmaceuticals, Inc. |
Cancer immunotherapy compositions and methods of use
|
|
CN101578297A
(zh)
|
2006-04-07 |
2009-11-11 |
美国政府健康及人类服务部 |
治疗肿瘤疾病的抗体组合物和方法
|
|
BRPI0714728A2
(pt)
|
2006-08-04 |
2013-05-14 |
Astrazeneca Ab |
agente de ligaÇço alvejado, anticorpo, composiÇço, linhagem de cÉlula isolada molÉcula de Ácido nucleico isolada, vetor, cÉlula hospedeira, mÉtodos para produzir um agente de ligaÇço alvejado, para isolar um anticorpo ou porÇço de ligaÇço de antÍgeno do mesmo, para fabricar um anticorpo monoclonal humano, para tratar, prevenir ou aliviar os sintomas de um distérbio, para inibir a proliferaÇço de uma cÉlula cancerosa, para inibir uma atividade de erbb2 em uma cÉlula que expressa erbb2, e para modular uma atividade de erbb2 em uma cÉlula que expressa erbb2, e, animal transgÊnico nço humano ou planta transgÊnica
|
|
RU2472807C2
(ru)
|
2006-09-08 |
2013-01-20 |
Эбботт Лэборетриз |
Интерлейкин-13-связывающие белки
|
|
US8455626B2
(en)
|
2006-11-30 |
2013-06-04 |
Abbott Laboratories |
Aβ conformer selective anti-aβ globulomer monoclonal antibodies
|
|
EP2124952A2
(en)
|
2007-02-27 |
2009-12-02 |
Abbott GmbH & Co. KG |
Method for the treatment of amyloidoses
|
|
WO2008112193A1
(en)
|
2007-03-12 |
2008-09-18 |
Dana-Farber Cancer Institute |
Prognostic, diagnostic, and cancer therapeutic uses of fanci and fanci modulating agents
|
|
SG182985A1
(en)
|
2007-04-02 |
2012-08-30 |
Amgen Fremont Inc |
Anti-ige antibodies
|
|
CN101801413A
(zh)
|
2007-07-12 |
2010-08-11 |
托勒克斯股份有限公司 |
采用gitr结合分子的联合疗法
|
|
CA2715080C
(en)
|
2007-09-28 |
2021-09-28 |
Intrexon Corporation |
Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof
|
|
CA2703263C
(en)
|
2007-11-01 |
2014-03-18 |
Perseid Therapeutics Llc |
Immunosuppressive polypeptides and nucleic acids
|
|
KR101577843B1
(ko)
|
2007-12-14 |
2015-12-16 |
브리스톨-마이어스 스큅 컴퍼니 |
인간 ｏｘ４０ 수용체에 대한 결합 분자
|
|
CN101909693A
(zh)
|
2008-01-08 |
2010-12-08 |
百时美施贵宝公司 |
用于治疗增殖性疾病的抗-ctla4抗体与微管蛋白调节剂的组合
|
|
EP2240204A1
(en)
|
2008-02-04 |
2010-10-20 |
Medarex, Inc. |
Anti-clta-4 antibodies with reduced blocking of binding of ctla-4 to b7 and uses thereof
|
|
JO2913B1
(en)
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
NZ588554A
(en)
|
2008-04-29 |
2013-03-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
MX343624B
(es)
|
2008-05-09 |
2016-11-14 |
Abbott Laboratories * |
Anticuerpos para receptor de productos finales de glucacion avanzada (rage) y usos de los mismos.
|
|
AR072001A1
(es)
|
2008-06-03 |
2010-07-28 |
Abbott Lab |
Inmunoglobulina con dominio variable dual y usos de la misma
|
|
KR20110016959A
(ko)
|
2008-06-03 |
2011-02-18 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
EP2810654A1
(en)
|
2008-07-08 |
2014-12-10 |
AbbVie Inc. |
Prostaglandin E2 binding proteins and uses thereof
|
|
US8822645B2
(en)
|
2008-07-08 |
2014-09-02 |
Abbvie Inc. |
Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
|
|
US8119129B2
(en)
|
2008-08-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Combination of anti-CTLA4 antibody with dasatinib for the treatment of proliferative diseases
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
PE20110774A1
(es)
|
2008-08-18 |
2011-10-13 |
Amgen Fremont Inc |
Anticuerpos para ccr2
|
|
KR101012267B1
(ko)
*
|
2008-08-29 |
2011-02-08 |
주식회사 세이프로드 |
파손이 방지되는 차선규제봉 및 차선규제봉 시공방법
|
|
WO2010042433A1
(en)
|
2008-10-06 |
2010-04-15 |
Bristol-Myers Squibb Company |
Combination of cd137 antibody and ctla-4 antibody for the treatment of proliferative diseases
|
|
DK2387627T3
(en)
|
2009-01-15 |
2016-07-04 |
Adaptive Biotechnologies Corp |
Adaptive immunity profiling and methods for producing monoclonal antibodies
|
|
NZ611324A
(en)
|
2009-03-05 |
2015-02-27 |
Abbvie Inc |
Il-17 binding proteins
|
|
US8283162B2
(en)
|
2009-03-10 |
2012-10-09 |
Abbott Laboratories |
Antibodies relating to PIVKAII and uses thereof
|
|
EP3659596A1
(en)
|
2009-07-20 |
2020-06-03 |
Bristol-Myers Squibb Company |
Combination of anti-ctla4 antibody with paclitaxel for the synergistic treatment of proliferative diseases
|
|
JP5903382B2
(ja)
|
2009-08-29 |
2016-04-13 |
アッヴィ・インコーポレイテッド |
治療用ｄｌｌ４結合タンパク質
|
|
PE20121530A1
(es)
|
2009-09-01 |
2012-12-22 |
Abbvie Inc |
Inmunoglobulinas con dominio variable dual
|
|
CA2777226A1
(en)
|
2009-10-12 |
2011-04-21 |
Pfizer Inc. |
Cancer treatment
|
|
JP2013507928A
(ja)
|
2009-10-15 |
2013-03-07 |
アボット・ラボラトリーズ |
二重可変ドメイン免疫グロブリンおよびその使用
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
WO2011053707A1
(en)
|
2009-10-31 |
2011-05-05 |
Abbott Laboratories |
Antibodies to receptor for advanced glycation end products (rage) and uses thereof
|
|
CA2780069C
(en)
|
2009-12-08 |
2018-07-17 |
Abbott Gmbh & Co. Kg |
Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
|
|
KR101853278B1
(ko)
|
2010-03-02 |
2018-05-02 |
애브비 인코포레이티드 |
치료학적 ｄｌｌ４ 결합 단백질
|
|
MX336196B
(es)
|
2010-04-15 |
2016-01-11 |
Abbvie Inc |
Proteinas de union a amiloide beta.
|
|
SG10201509747VA
(en)
|
2010-05-14 |
2015-12-30 |
Abbvie Inc |
Il-1 binding proteins
|
|
US20130064831A1
(en)
|
2010-05-17 |
2013-03-14 |
Bristol-Myers Squibb Company |
Immunotherapeutic dosing regimens and combinations thereof
|
|
US20120009196A1
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
US9120862B2
(en)
|
2010-07-26 |
2015-09-01 |
Abbott Laboratories |
Antibodies relating to PIVKA-II and uses thereof
|
|
SG188190A1
(en)
|
2010-08-03 |
2013-04-30 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
WO2012024187A1
(en)
|
2010-08-14 |
2012-02-23 |
Abbott Laboratories |
Amyloid-beta binding proteins
|
|
EP2606067B1
(en)
|
2010-08-19 |
2018-02-21 |
Zoetis Belgium S.A. |
Anti-ngf antibodies and their use
|
|
KR20130139884A
(ko)
|
2010-08-26 |
2013-12-23 |
애브비 인코포레이티드 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
DK2646552T3
(en)
*
|
2010-12-02 |
2017-10-23 |
Pieris Pharmaceuticals Gmbh |
MUTEINES OF HUMAN LIPOCALIN 2 WITH AFFINITY FOR CTLA-4
|
|
KR101781546B1
(ko)
|
2010-12-14 |
2017-09-26 |
내셔널 유니버시티 오브 싱가포르 |
뎅기 바이러스 세로타입 1 e 프로틴에 특이적인 인간 단일클론 항체 및 그들의 용도
|
|
TW201307388A
(zh)
|
2010-12-21 |
2013-02-16 |
Abbott Lab |
Ｉｌ－１結合蛋白
|
|
RU2627171C2
(ru)
|
2010-12-21 |
2017-08-03 |
Эббви Инк. |
Il-1 альфа и бета биспецифические иммуноглобулины с двойными вариабельными доменами и их применение
|
|
GB201103955D0
(en)
*
|
2011-03-09 |
2011-04-20 |
Antitope Ltd |
Antibodies
|
|
WO2012142164A1
(en)
|
2011-04-12 |
2012-10-18 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
|
|
DK2728002T3
(da)
|
2011-06-30 |
2022-04-04 |
Chugai Pharmaceutical Co Ltd |
Heterodimeriseret polypeptid
|
|
MX2014000531A
(es)
|
2011-07-13 |
2014-12-05 |
Abbvie Inc |
Metodos y composiciones para el tratamiento del asma usando anticuerpos anti-il-13.
|
|
WO2013013029A1
(en)
|
2011-07-19 |
2013-01-24 |
The Board Of Trustees Of The University Of Illinois |
Anti-clta4, anti-glut2 protein for the treatment of type 1 diabetes
|
|
UA116528C2
(uk)
|
2011-08-30 |
2018-04-10 |
Астекс Фармасьютікалз, Інк. |
Склад, набір, фармацевтична композиція, що містять похідні децитабіну, їх отримання і застосування
|
|
PE20141545A1
(es)
|
2011-10-24 |
2014-11-26 |
Abbvie Inc |
Inmunoenlazadores dirigidos contra el tnf
|
|
MX2014004977A
(es)
|
2011-10-24 |
2014-09-11 |
Abbvie Inc |
Inmunoaglutinantes dirigidos contra esclerostina.
|
|
IN2014CN04183A
(Direct)
|
2011-11-08 |
2015-07-17 |
Pfizer |
|
|
CA3204283A1
(en)
|
2011-12-14 |
2013-06-20 |
AbbVie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
|
JP6336397B2
(ja)
|
2011-12-14 |
2018-06-06 |
アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー |
鉄関連障害を診断および治療するための組成物および方法
|
|
US9120870B2
(en)
|
2011-12-30 |
2015-09-01 |
Abbvie Inc. |
Dual specific binding proteins directed against IL-13 and IL-17
|
|
IL316441A
(en)
|
2012-01-27 |
2024-12-01 |
Abbvie Inc |
Composition and method for diagnosing and treating diseases associated with axonal degeneration of nerve cells
|
|
WO2013138702A2
(en)
|
2012-03-15 |
2013-09-19 |
Bristol-Myers Squibb Company |
Methods for predicting gastrointestinal immune-related adverse events (gi-irae) in patients treated with modulation of the co-stimulatory pathway
|
|
US20150079100A1
(en)
|
2012-03-23 |
2015-03-19 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla-4 antibodies
|
|
WO2013155447A1
(en)
|
2012-04-13 |
2013-10-17 |
Children's Medical Center Corporation |
Tiki inhibitors
|
|
EP3563865A3
(en)
|
2012-05-04 |
2019-12-04 |
Pfizer Inc |
Prostate-associated antigens and vaccine-based immunotherapy regimens
|
|
US20150118244A1
(en)
|
2012-05-10 |
2015-04-30 |
Bristol-Myers Squibb Company |
Anti-tumor antibodies as predictive or prognostic biomarkers of efficacy and survival in ipilimumab-treated patients
|
|
KR102702287B1
(ko)
|
2012-05-15 |
2024-09-04 |
브리스톨-마이어스 스큅 컴퍼니 |
Pd-1/pd-l1 신호전달을 방해하는 것에 의한 암 면역요법
|
|
ES2894852T3
(es)
|
2012-06-06 |
2022-02-16 |
Zoetis Services Llc |
Anticuerpos anti-NGF caninizados y métodos de los mismos
|
|
AR091649A1
(es)
|
2012-07-02 |
2015-02-18 |
Bristol Myers Squibb Co |
Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
|
|
WO2014011955A2
(en)
|
2012-07-12 |
2014-01-16 |
Abbvie, Inc. |
Il-1 binding proteins
|
|
AR092219A1
(es)
*
|
2012-08-23 |
2015-04-08 |
Seattle Genetics Inc |
Conjugados anticuerpo-farmaco (adc) que se unen a proteinas 158p1d7
|
|
KR20210111353A
(ko)
|
2012-11-01 |
2021-09-10 |
애브비 인코포레이티드 |
항-ｖｅｇｆ／ｄｌｌ4 이원 가변 도메인 면역글로불린 및 이의 용도
|
|
US9550986B2
(en)
|
2012-12-21 |
2017-01-24 |
Abbvie Inc. |
High-throughput antibody humanization
|
|
LT2961388T
(lt)
|
2013-03-01 |
2019-08-26 |
Astex Pharmaceuticals, Inc. |
Vaistų deriniai
|
|
SG11201507563SA
(en)
|
2013-03-14 |
2015-10-29 |
Parkash Gill |
Cancer treatment using antibodies that bind cell surface grp78
|
|
MX376492B
(es)
|
2013-03-14 |
2025-03-07 |
Abbott Lab |
Anticuerpos monoclonares que se unen al dominio de unión a lípidos de la proteína de la cápside del virus de la hepatitis c (vhc)
|
|
CA2906421C
(en)
|
2013-03-14 |
2022-08-16 |
George J. Dawson |
Hcv antigen-antibody combination assay and methods and compositions for use therein
|
|
CA2906407A1
(en)
|
2013-03-14 |
2014-09-18 |
Abbott Laboratories |
Hcv ns3 recombinant antigens and mutants thereof for improved antibody detection
|
|
TW201512219A
(zh)
|
2013-03-15 |
2015-04-01 |
Abbvie Inc |
針對ＩＬ－１β及／或ＩＬ－１７之雙特異性結合蛋白
|
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
|
ES2753419T3
(es)
|
2013-06-07 |
2020-04-08 |
Univ Duke |
Inhibidores del factor H del complemento
|
|
LT3030262T
(lt)
|
2013-08-08 |
2020-03-10 |
Cytune Pharma |
Kombinuota farmacinė kompozicija
|
|
PT3444271T
(pt)
|
2013-08-08 |
2022-01-05 |
Inst Nat Sante Rech Med |
Modulocinas baseadas em il-15 e no domínio sushi de il-15ralfa
|
|
LT3178849T
(lt)
|
2013-09-20 |
2019-06-10 |
Bristol-Myers Squibb Company |
Anti-lag-3 antikūnų ir anti-pd-1 antikūnų derinys, skirtas navikų gydymui
|
|
WO2015063647A1
(en)
|
2013-11-01 |
2015-05-07 |
Pfizer Inc. |
Vectors for expression of prostate-associated antigens
|
|
ES2991853T3
(es)
|
2013-11-05 |
2024-12-05 |
Cognate Bioservices Inc |
Combinaciones de inhibidores del punto de control y terapéuticos para tratar el cáncer
|
|
EP3066127A1
(en)
|
2013-11-06 |
2016-09-14 |
Bristol-Myers Squibb Company |
Immunotherapeutic dosing regimens and combinations thereof
|
|
WO2015104406A2
(en)
|
2014-01-13 |
2015-07-16 |
Pieris Ag |
Multi-specific polypeptide useful for localized tumor immunomodulation
|
|
JP6847666B2
(ja)
|
2014-05-28 |
2021-03-24 |
アジェナス インコーポレイテッド |
抗ｇｉｔｒ抗体及びその使用法
|
|
EA037006B1
(ru)
|
2014-06-06 |
2021-01-26 |
Бристол-Майерс Сквибб Компани |
Антитела к индуцируемому глюкокортикоидами рецептору фактора некроза опухолей (gitr) и их применения
|
|
CN105296433B
(zh)
|
2014-08-01 |
2018-02-09 |
中山康方生物医药有限公司 |
一种ctla4抗体、其药物组合物及其用途
|
|
PT3186281T
(pt)
|
2014-08-28 |
2019-07-10 |
Halozyme Inc |
Terapia de combinação com uma enzima de degradação de hialuronano e um inibidor de pontos de verificação imunológica
|
|
AU2015318018B2
(en)
|
2014-09-16 |
2017-05-11 |
Synermore Biologics (Suzhou) Co. Ltd. |
Anti-EGFR antibody and uses of same
|
|
JP6991857B2
(ja)
|
2014-10-10 |
2022-01-13 |
イデラ ファーマシューティカルズ インコーポレイテッド |
Ｔｌｒ９アゴニストをチェックポイント阻害剤と共に用いるがんの治療
|
|
NZ746680A
(en)
|
2014-10-14 |
2020-07-31 |
Halozyme Inc |
Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same
|
|
WO2016070769A1
(zh)
*
|
2014-11-04 |
2016-05-12 |
北京韩美药品有限公司 |
同时阻断b7/cd28和il6/il6r/gp130信号通路的重组融合蛋白
|
|
CN105597090B
(zh)
*
|
2014-11-14 |
2022-08-23 |
中国科学院上海营养与健康研究所 |
一种提高cd4阳性t淋巴细胞存活率和活性的试剂及其应用
|
|
ES2986091T3
(es)
|
2014-11-21 |
2024-11-08 |
Bristol Myers Squibb Co |
Anticuerpos frente a CD73 y sus usos
|
|
RS60998B1
(sr)
|
2014-11-21 |
2020-11-30 |
Bristol Myers Squibb Co |
Antitela koja sadrže modifikovane regione teškog lanca
|
|
WO2016090070A1
(en)
|
2014-12-04 |
2016-06-09 |
Bristol-Myers Squibb Company |
Combination of anti-cs1 and anti-pd1 antibodies to treat cancer (myeloma)
|
|
CN104387453A
(zh)
*
|
2014-12-08 |
2015-03-04 |
深圳市同康生物医药有限公司 |
树突状细胞靶向肽及编码基因及应用
|
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
|
KR102644115B1
(ko)
|
2014-12-23 |
2024-03-05 |
브리스톨-마이어스 스큅 컴퍼니 |
Tigit에 대한 항체
|
|
JP6885867B2
(ja)
|
2014-12-31 |
2021-06-16 |
チェックメイト ファーマシューティカルズ， インコーポレイテッド |
組合せ腫瘍免疫療法
|
|
WO2016127052A1
(en)
|
2015-02-05 |
2016-08-11 |
Bristol-Myers Squibb Company |
Cxcl11 and smica as predictive biomarkers for efficacy of anti-ctla4 immunotherapy
|
|
JP6917902B2
(ja)
*
|
2015-02-13 |
2021-08-11 |
ソレント・セラピューティクス・インコーポレイテッド |
Ｃｔｌａ４に結合する抗体医薬
|
|
US20180133327A1
(en)
|
2015-03-16 |
2018-05-17 |
Amal Therapeutics Sa |
Cell Penetrating Peptides and Complexes Comprising the Same
|
|
WO2016154629A1
(en)
|
2015-03-26 |
2016-09-29 |
Woman & Infants' Hospital Of Rhode Island |
Therapy for malignant disease
|
|
CN107530432B
(zh)
|
2015-04-07 |
2021-04-27 |
Cytlimic公司 |
药物
|
|
KR102138209B1
(ko)
|
2015-05-06 |
2020-07-28 |
스니프르 테크놀로지스 리미티드 |
미생물 개체군 변경 및 미생물군 변형
|
|
JP7028765B2
(ja)
|
2015-05-22 |
2022-03-02 |
トランスレイショナル・ドラッグ・ディベロップメント・エルエルシー |
ベンズアミドおよび活性化合物組成物および使用方法
|
|
DK3303396T5
(da)
|
2015-05-29 |
2024-10-07 |
Bristol Myers Squibb Co |
Antistoffer mod ox40 og anvendelser deraf
|
|
ES2774016T3
(es)
|
2015-05-29 |
2020-07-16 |
Abbvie Inc |
Anticuerpos anti-cd40 y usos de los mismos
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
|
|
BR112017027692A2
(pt)
|
2015-06-29 |
2018-10-09 |
Bristol Myers Squibb Co |
regimes de dosagem imunoterapêuticos compreendendo pomalidomida e um anticorpo anti-cs1 para tratamento do câncer
|
|
BR112017028353A2
(pt)
|
2015-06-29 |
2018-09-04 |
The Rockfeller University |
anticorpos para cd40 com atividade agonista melhorada
|
|
US10485764B2
(en)
|
2015-07-02 |
2019-11-26 |
Otsuka Pharmaceutical Co., Ltd. |
Lyophilized pharmaceutical compositions
|
|
MX2018000619A
(es)
|
2015-07-16 |
2019-03-06 |
Bioxcel Therapeutics Inc |
Nuevo enfoque para tratar el cancer mediante el uso de la inmunomodulacion.
|
|
EP3744340A3
(en)
|
2015-07-16 |
2021-03-03 |
Biokine Therapeutics Ltd. |
Compositions and methods for treating cancer
|
|
WO2017021913A1
(en)
|
2015-08-04 |
2017-02-09 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatments and uses and methods thereof
|
|
WO2017025871A1
(en)
|
2015-08-07 |
2017-02-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy comprising anti ctla-4 antibodies
|
|
EP4548979A3
(en)
|
2015-09-11 |
2025-07-23 |
Nascent Biotech, Inc. |
Enhanced delivery of drugs to the brain
|
|
US11594135B2
(en)
|
2015-11-02 |
2023-02-28 |
Memgen, Inc. |
Methods of CD40 activation and immune checkpoint blockade
|
|
WO2017079215A1
(en)
|
2015-11-03 |
2017-05-11 |
Glycomimetics, Inc. |
Methods and compositions for the production of monoclonal antibodies, hematopoietic stem cells, and methods of using the same
|
|
CA3004530A1
(en)
|
2015-11-07 |
2017-05-11 |
Multivir Inc. |
Methods and compositions comprising tumor suppressor gene therapy and immune checkpoint blockade for the treatment of cancer
|
|
MX2018006072A
(es)
|
2015-11-19 |
2018-08-01 |
Squibb Bristol Myers Co |
Anticuerpos contra receptor de factor de necrosis de tumor inducido por glucocorticoides (gitr) y usos de los mismos.
|
|
AU2016364889B2
(en)
|
2015-12-02 |
2024-01-04 |
Agenus Inc. |
Antibodies and methods of use thereof
|
|
MX2018007089A
(es)
|
2015-12-14 |
2019-01-30 |
Macrogenics Inc |
Moleculas biespecificas que tienen inmunorreactividad con pd-1 y ctla-4, y metodos de uso de las mismas.
|
|
EP3400023A1
(en)
|
2016-01-10 |
2018-11-14 |
ModernaTX, Inc. |
Therapeutic mrnas encoding anti ctla-4 antibodies
|
|
SG11201806861SA
(en)
|
2016-03-04 |
2018-09-27 |
Bristol Myers Squibb Co |
Combination therapy with anti-cd73 antibodies
|
|
WO2017160599A1
(en)
|
2016-03-14 |
2017-09-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Use of cd300b antagonists to treat sepsis and septic shock
|
|
AU2017234163B2
(en)
|
2016-03-15 |
2023-01-19 |
Mersana Therapeutics, Inc. |
NaPi2b-targeted antibody-drug conjugates and methods of use thereof
|
|
RU2769314C1
(ru)
|
2016-03-16 |
2022-03-30 |
Амаль Терапьютикс Са |
Комбинация модулятора иммунных контрольных точек и комплекса, содержащего проникающий в клетку пептид, карго-молекулу и пептидный агонист tlr, для применения в медицине
|
|
US11046782B2
(en)
|
2016-03-30 |
2021-06-29 |
Musc Foundation For Research Development |
Methods for treatment and diagnosis of cancer by targeting glycoprotein A repetitions predominant (GARP) and for providing effective immunotherapy alone or in combination
|
|
WO2017173334A1
(en)
|
2016-04-01 |
2017-10-05 |
Checkmate Pharmaceuticals, Inc. |
Fc receptor-mediated drug delivery
|
|
MX393066B
(es)
|
2016-04-18 |
2025-03-24 |
Celldex Therapeutics Inc |
Anticuerpos agonistas que se unen a cd40 humana y usos de los mismos.
|
|
DK3449017T3
(da)
|
2016-04-29 |
2022-03-14 |
Univ Texas |
Målrettet måling af transkriptionel aktivitet vedrørende hormonreceptorer
|
|
US20190298824A1
(en)
|
2016-05-04 |
2019-10-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv |
Albumin-binding immunomodulatory compositions and methods of use thereof
|
|
CA3024509A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Mrna combination therapy for the treatment of cancer
|
|
CN109641044A
(zh)
|
2016-05-30 |
2019-04-16 |
吉奥瓦科斯公司 |
用于产生对乙型肝炎病毒的免疫应答的组合物和方法
|
|
US10994033B2
(en)
|
2016-06-01 |
2021-05-04 |
Bristol-Myers Squibb Company |
Imaging methods using 18F-radiolabeled biologics
|
|
GB201609811D0
(en)
|
2016-06-05 |
2016-07-20 |
Snipr Technologies Ltd |
Methods, cells, systems, arrays, RNA and kits
|
|
IL263834B2
(en)
|
2016-06-20 |
2024-01-01 |
Kymab Ltd |
Anti-pd-l1 antibodies
|
|
CN109983121A
(zh)
|
2016-06-30 |
2019-07-05 |
昂克诺斯公司 |
治疗性多肽的假型化溶瘤病毒递送
|
|
ES3005961T3
(en)
|
2016-07-14 |
2025-03-17 |
Bristol Myers Squibb Co |
Antibodies against tim3 and uses thereof
|
|
NL2017270B1
(en)
*
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
|
US11649289B2
(en)
|
2016-08-04 |
2023-05-16 |
Glaxosmithkline Intellectual Property Development Limited |
Anti-ICOS and anti-PD-1 antibody combination therapy
|
|
WO2018035710A1
(en)
|
2016-08-23 |
2018-03-01 |
Akeso Biopharma, Inc. |
Anti-ctla4 antibodies
|
|
CN109963585B
(zh)
|
2016-09-21 |
2024-10-15 |
阿尔勒治疗公司 |
包括细胞穿透肽、多表位和tlr肽激动剂的用于治疗癌症的融合物
|
|
EP3518946A4
(en)
|
2016-09-27 |
2020-09-09 |
Board of Regents, The University of Texas System |
METHODS TO IMPROVE IMMUNE CHECKPOINT BLOCKING TREATMENT BY MODULATING THE MICROBIOME
|
|
EP4521116A3
(en)
|
2016-10-03 |
2025-05-28 |
Abbott Laboratories |
Improved methods of assessing uch-l1 status in patient samples
|
|
WO2018068182A1
(en)
*
|
2016-10-10 |
2018-04-19 |
Crown Bioscience (Taicang) Inc. |
Novel anti-ctla4 antibodies
|
|
CA3039033A1
(en)
|
2016-10-11 |
2018-04-19 |
Cytlimic Inc. |
Medicine
|
|
EP3525809A4
(en)
|
2016-10-12 |
2020-06-03 |
Board of Regents, The University of Texas System |
METHOD AND COMPOSITIONS FOR TUSC2 IMMUNOTHERAPY
|
|
EP3532504A1
(en)
|
2016-10-28 |
2019-09-04 |
Bristol-Myers Squibb Company |
Methods of treating urothelial carcinoma using an anti-pd-1 antibody
|
|
CN110312523B
(zh)
*
|
2016-11-08 |
2024-04-26 |
齐鲁皮吉特湾生物治疗有限公司 |
抗pd1和抗ctla4抗体
|
|
MA46770A
(fr)
|
2016-11-09 |
2019-09-18 |
Agenus Inc |
Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
|
|
CA3043356A1
(en)
|
2016-11-09 |
2018-05-17 |
Musc Foundation For Research Development |
Cd38-nad+ regulated metabolic axis in anti-tumor immunotherapy
|
|
CU20190051A7
(es)
|
2016-11-17 |
2020-01-03 |
Univ Texas |
Compuestos con actividad antitumoral contra células cancerosas que tienen mutaciones en el exón 20 de egfr o her2
|
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
|
AU2017363337B2
(en)
|
2016-11-23 |
2021-07-01 |
Translational Drug Development, Llc |
Benzamide and active compound compositions and methods of use
|
|
WO2018099539A1
(en)
|
2016-11-29 |
2018-06-07 |
Horst Lindhofer |
Combination of t-cell redirecting multifunctional antibodies with immune checkpoint modulators and uses thereof
|
|
AU2017368923A1
(en)
|
2016-12-01 |
2019-06-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapy
|
|
KR20190090823A
(ko)
|
2016-12-01 |
2019-08-02 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
조합 요법
|
|
SG10201912575RA
(en)
|
2016-12-12 |
2020-02-27 |
Daiichi Sankyo Co Ltd |
Combination of antibody-drug conjugate and immune checkpoint inhibitor
|
|
CN110381997A
(zh)
|
2016-12-12 |
2019-10-25 |
茂体外尔公司 |
用于治疗和预防癌症和感染性疾病的包含病毒基因治疗和免疫检查点抑制剂的方法和组合物
|
|
TWI674261B
(zh)
|
2017-02-17 |
2019-10-11 |
美商英能腫瘤免疫股份有限公司 |
Nlrp3 調節劑
|
|
WO2018156250A1
(en)
*
|
2017-02-21 |
2018-08-30 |
Remd Biotherapeutics, Inc. |
Cancer treatment using antibodies that bind cytotoxic t-lymphocyte antigen-4 (ctla-4)
|
|
CA3054571A1
(en)
|
2017-02-24 |
2018-08-30 |
Board Of Regents,The University Of Texas System |
Assay for detection of early stage pancreatic cancer
|
|
WO2018160538A1
(en)
|
2017-02-28 |
2018-09-07 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
|
EP3366703B1
(en)
|
2017-02-28 |
2019-04-03 |
Ralf Kleef |
Immune checkpoint therapy with hyperthermia
|
|
EP3596469A1
(en)
|
2017-03-12 |
2020-01-22 |
Yeda Research and Development Co., Ltd. |
Methods of diagnosing and prognosing cancer
|
|
WO2018167780A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of prognosing and treating cancer
|
|
CA3052513A1
(en)
|
2017-03-23 |
2018-09-27 |
Abbott Laboratories |
Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1
|
|
CA3058175A1
(en)
|
2017-03-31 |
2018-10-04 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
TWI788340B
(zh)
|
2017-04-07 |
2023-01-01 |
美商必治妥美雅史谷比公司 |
抗icos促效劑抗體及其用途
|
|
EP3610268B1
(en)
|
2017-04-15 |
2025-09-24 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers
|
|
CN110621341A
(zh)
|
2017-04-26 |
2019-12-27 |
百时美施贵宝公司 |
使二硫键还原最小化的抗体生产方法
|
|
WO2018200823A1
(en)
|
2017-04-28 |
2018-11-01 |
Abbott Laboratories |
Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject
|
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
|
CN108948194B
(zh)
*
|
2017-05-19 |
2023-02-17 |
上海药明生物技术有限公司 |
一种新的ctla-4单克隆抗体
|
|
EA201992755A1
(ru)
*
|
2017-05-19 |
2020-04-22 |
Уси Байолоджикс (Шанхай) Ко. Лтд. |
Новые моноклональные антитела к белку 4, ассоциированному с цитотоксическими т-лимфоцитами, (ctla-4)
|
|
AU2018272852B2
(en)
|
2017-05-25 |
2025-02-13 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
BR112019024701A2
(pt)
|
2017-05-25 |
2020-06-09 |
Abbott Laboratories |
métodos para auxiliar na determinação se um exame de imagem deve ser realizado em um indivíduo humano que sofreu ou pode ter sofrido uma lesão na cabeça com o uso de biomarcadores precoces
|
|
ES2965352T3
(es)
|
2017-05-30 |
2024-04-12 |
Bristol Myers Squibb Co |
Tratamiento de tumores positivos a gen 3 de activación de linfocitos (LAG-3)
|
|
WO2018222711A2
(en)
|
2017-05-30 |
2018-12-06 |
Bristol-Myers Squibb Company |
Compositions comprising a combination of an anti-lag-3 antibody, a pd-1 pathway inhibitor, and an immunotherapeutic agent
|
|
JP7269183B2
(ja)
|
2017-05-30 |
2023-05-08 |
アボット・ラボラトリーズ |
心臓トロポニンｉを使用する、ヒト対象における軽度外傷性脳損傷を診断及び査定する一助となるための方法
|
|
JP7301002B2
(ja)
|
2017-05-30 |
2023-06-30 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗ｌａｇ－３抗体または抗ｌａｇ－３抗体および抗ｐｄ－１もしくは抗ｐｄ－ｌ１抗体を含む組成物
|
|
CN110719799A
(zh)
|
2017-06-09 |
2020-01-21 |
俄勒冈州普罗维登斯健康与服务部 |
Cd39和cd103在鉴定用于癌症治疗的人肿瘤反应性t细胞中的应用
|
|
WO2019010131A1
(en)
|
2017-07-03 |
2019-01-10 |
Abbott Laboratories |
IMPROVED METHODS FOR MEASURING CARBOXY TERMINATION HYDROLASE LEVELS OF UBIQUITIN L1 IN BLOOD
|
|
NZ761519A
(en)
|
2017-07-14 |
2023-07-28 |
Innate Tumor Immunity Inc |
Nlrp3 modulators
|
|
US20190169291A1
(en)
|
2017-07-14 |
2019-06-06 |
Pfizer Inc. |
Antibodies to MAdCAM
|
|
TWI799432B
(zh)
*
|
2017-07-27 |
2023-04-21 |
美商再生元醫藥公司 |
抗ctla-4抗體及其用途
|
|
US10519190B2
(en)
|
2017-08-03 |
2019-12-31 |
Otsuka Pharmaceutical Co., Ltd. |
Drug compound and purification methods thereof
|
|
WO2019036855A1
(en)
|
2017-08-21 |
2019-02-28 |
Adagene Inc. |
Anti-cd137 molecules and use thereof
|
|
WO2019067913A1
(en)
|
2017-09-29 |
2019-04-04 |
Bristol-Myers Squibb Company |
COMPOSITIONS AND METHODS OF TREATING CANCER
|
|
JP2020536114A
(ja)
|
2017-10-06 |
2020-12-10 |
ザ ウィスター インスティテュート オブ アナトミー アンド バイオロジー |
癌の処置および予防のためｃｔｌａ−４を標的とするｄｎａモノクローナル抗体
|
|
WO2019075090A1
(en)
|
2017-10-10 |
2019-04-18 |
Tilos Therapeutics, Inc. |
ANTI-LAP ANTIBODIES AND USES THEREOF
|
|
AU2018346957B2
(en)
|
2017-10-12 |
2024-08-01 |
Board Of Regents, The University Of Texas System |
T cell receptors for immunotherapy
|
|
EP3694884A1
(en)
|
2017-10-15 |
2020-08-19 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
KR20200074214A
(ko)
|
2017-11-01 |
2020-06-24 |
브리스톨-마이어스 스큅 컴퍼니 |
암을 치료하는데 사용하기 위한 면역자극 효능작용 항체
|
|
WO2019094360A1
(en)
|
2017-11-07 |
2019-05-16 |
The Board Of Regents Of The University Of Texas System |
Targeting lilrb4 with car-t or car-nk cells in the treatment of cancer
|
|
US11638760B2
(en)
|
2017-11-27 |
2023-05-02 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
CN108003238B
(zh)
*
|
2017-11-30 |
2021-02-02 |
常州费洛斯药业科技有限公司 |
一种能特异识别ctla-4的全人源单克隆抗体或抗体片段及其方法和用途
|
|
CN110892266A
(zh)
|
2017-12-09 |
2020-03-17 |
雅培实验室 |
使用gfap和uch-l1的组合辅助诊断和评价人类受试者中创伤性脑损伤的方法
|
|
EP3721233A2
(en)
|
2017-12-09 |
2020-10-14 |
Abbott Laboratories |
Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
|
|
JP7087107B2
(ja)
*
|
2017-12-20 |
2022-06-20 |
ハーバー・バイオメド・（シャンハイ）・カンパニー・リミテッド |
Ｃｔｌａ－４に結合する抗体およびその使用
|
|
WO2019126691A1
(en)
|
2017-12-21 |
2019-06-27 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
|
KR102813744B1
(ko)
|
2017-12-27 |
2025-05-28 |
브리스톨-마이어스 스큅 컴퍼니 |
항-cd40 항체 및 그의 용도
|
|
WO2019133847A1
(en)
|
2017-12-29 |
2019-07-04 |
Oncorus, Inc. |
Oncolytic viral delivery of therapeutic polypeptides
|
|
CN120192415A
(zh)
|
2018-01-12 |
2025-06-24 |
百时美施贵宝公司 |
抗tim3抗体及其用途
|
|
JP2021511344A
(ja)
|
2018-01-22 |
2021-05-06 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
癌を治療する組成物および方法
|
|
WO2019148445A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Precision/context-dependent activatable antibodies, and methods of making and using the same
|
|
EP3752194A4
(en)
|
2018-02-13 |
2022-03-16 |
Checkmate Pharmaceuticals, Inc. |
COMPOSITIONS AND METHODS FOR TUMOR IMMUNOTHERAPY
|
|
CN112218658A
(zh)
|
2018-03-12 |
2021-01-12 |
国家健康科学研究所 |
热量限制模拟物用于增强癌症治疗的化学免疫疗法的用途
|
|
JP2021517461A
(ja)
|
2018-03-12 |
2021-07-26 |
ゾエティス・サービシーズ・エルエルシー |
抗ｎｇｆ抗体およびその方法
|
|
WO2019179388A1
(en)
*
|
2018-03-19 |
2019-09-26 |
Wuxi Biologics (Shanghai) Co., Ltd. |
Novel anti-ctla-4 antibody polypeptide
|
|
KR20200135986A
(ko)
|
2018-03-19 |
2020-12-04 |
멀티비르 인코포레이티드 |
종양 억제인자 유전자 치료 및 cd122/cd132 작용제를 포함하는 암 치료를 위한 방법 및 조성물
|
|
TW201945393A
(zh)
|
2018-03-21 |
2019-12-01 |
美商戊瑞治療有限公司 |
在酸性pH結合至VISTA之抗體
|
|
EP3768715A1
(en)
|
2018-03-23 |
2021-01-27 |
Bristol-Myers Squibb Company |
Antibodies against mica and/or micb and uses thereof
|
|
US10760075B2
(en)
|
2018-04-30 |
2020-09-01 |
Snipr Biome Aps |
Treating and preventing microbial infections
|
|
EP3773685A1
(en)
|
2018-03-25 |
2021-02-17 |
SNIPR Biome ApS. |
Treating & preventing microbial infections
|
|
EP3773551B1
(en)
|
2018-03-27 |
2024-10-16 |
Board of Regents, The University of Texas System |
Compounds with anti-tumor activity against cancer cells bearing her2 exon 19 mutations
|
|
US20210032344A1
(en)
|
2018-03-30 |
2021-02-04 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
IL277680B2
(en)
|
2018-04-09 |
2025-08-01 |
Checkmate Pharmaceuticals Inc |
Packaging oligonucleotides into virus-like particles
|
|
KR20210003170A
(ko)
|
2018-04-18 |
2021-01-11 |
젠코어 인코포레이티드 |
IL-15/IL-15Rα 이종이량체 Fc 융합 단백질 및 이의 용도
|
|
WO2019204665A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
|
EP4353235A3
(en)
|
2018-04-25 |
2024-07-31 |
Innate Tumor Immunity, Inc. |
Nlrp3 modulators
|
|
EP3810109B1
(en)
|
2018-05-31 |
2024-08-07 |
Peloton Therapeutics, Inc. |
Compounds and compositions for inhibiting cd73
|
|
WO2019241358A2
(en)
|
2018-06-12 |
2019-12-19 |
The Regents Of The University Of California |
Single-chain bispecific chimeric antigen receptors for the treatment of cancer
|
|
MY201995A
(en)
|
2018-07-09 |
2024-03-28 |
Five Prime Therapeutics Inc |
Antibodies binding to ilt4
|
|
KR20210031722A
(ko)
|
2018-07-11 |
2021-03-22 |
파이브 프라임 테라퓨틱스, 인크. |
산성 pH에서 VISTA에 결합하는 항체
|
|
CN112673092B
(zh)
|
2018-07-11 |
2024-03-29 |
阿克蒂姆治疗有限公司 |
工程化的免疫刺激性细菌菌株及其用途
|
|
EP3823673A4
(en)
|
2018-07-20 |
2022-05-11 |
Surface Oncology, Inc. |
Anti-cd112r compositions and methods
|
|
US12024513B2
(en)
|
2018-08-16 |
2024-07-02 |
Innate Tumor Immunity, Inc. |
NLRP3 modulators
|
|
JP7364663B2
(ja)
|
2018-08-16 |
2023-10-18 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
イミダゾ［４，５－ｃ］キノリン誘導体のＮＬＲＰ３モジュレーター
|
|
CA3109778A1
(en)
|
2018-08-16 |
2020-02-20 |
Innate Tumor Immunity, Inc. |
Substitued 4-amino-1h-imidazo[4,5-c]quinoline compounds and improved methods for their preparation
|
|
EP3617230A1
(en)
|
2018-09-03 |
2020-03-04 |
BioInvent International AB |
Novel antibodies and nucleotide sequences, and uses thereof
|
|
WO2020048942A1
(en)
|
2018-09-04 |
2020-03-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cytotoxic t lymphocyte-dependent immune responses
|
|
WO2020058372A1
(en)
|
2018-09-19 |
2020-03-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical composition for the treatment of cancers resistant to immune checkpoint therapy
|
|
CA3098765A1
(en)
|
2018-09-21 |
2020-03-26 |
Innovent Biologics (Suzhou) Co., Ltd. |
Novel interleukin-2 and use thereof
|
|
AU2019343251B2
(en)
|
2018-09-21 |
2022-06-09 |
Innovent Biologics (Suzhou) Co., Ltd. |
Novel interleukin 2 and use thereof
|
|
US20220040183A1
(en)
|
2018-10-01 |
2022-02-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of inhibitors of stress granule formation for targeting the regulation of immune responses
|
|
MA53822A
(fr)
|
2018-10-03 |
2021-08-11 |
Xencor Inc |
Protéines de fusion fc hétérodimères d'il -12
|
|
EP3863722A2
(en)
|
2018-10-10 |
2021-08-18 |
Tilos Theapeutics, Inc. |
Anti-lap antibody variants and uses thereof
|
|
MX2021004059A
(es)
|
2018-10-12 |
2021-09-23 |
Xencor Inc |
Proteínas de fusión de il-15/il-15ralfa-fc dirigidas a pd-1 y usos de las mismas en terapias combinadas.
|
|
KR20210081384A
(ko)
|
2018-10-23 |
2021-07-01 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
US20230021500A1
(en)
|
2018-10-29 |
2023-01-26 |
Mersana Therapeutics, Inc. |
Cysteine engineered antibody-drug conjugates with peptide-containing linkers
|
|
CN120594829A
(zh)
|
2018-11-09 |
2025-09-05 |
皮埃里亚生物科学有限责任公司 |
用于测定肿瘤微环境组成的方法和组合物
|
|
KR20210092769A
(ko)
|
2018-11-16 |
2021-07-26 |
브리스톨-마이어스 스큅 컴퍼니 |
항-nkg2a 항체 및 그의 용도
|
|
EP3883955A1
(en)
|
2018-11-19 |
2021-09-29 |
Board of Regents, The University of Texas System |
A modular, polycistronic vector for car and tcr transduction
|
|
US20220018828A1
(en)
|
2018-11-28 |
2022-01-20 |
Inserm (Institut National De La Santé Et La Recherche Médicale |
Methods and kit for assaying lytic potential of immune effector cells
|
|
KR20210096638A
(ko)
|
2018-11-28 |
2021-08-05 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
억제성 환경에 대한 기능 및 내성을 증진시키기 위한 면역 세포의 멀티플렉스 게놈 편집
|
|
US20220106400A1
(en)
|
2018-11-28 |
2022-04-07 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
US20220033778A1
(en)
|
2018-11-29 |
2022-02-03 |
Board Of Regents, The University Of Texas System |
Methods for ex vivo expansion of natural killer cells and use thereof
|
|
EP3891270A1
(en)
|
2018-12-07 |
2021-10-13 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Use of cd26 and cd39 as new phenotypic markers for assessing maturation of foxp3+ t cells and uses thereof for diagnostic purposes
|
|
TW202039459A
(zh)
|
2018-12-11 |
2020-11-01 |
美商施萬生物製藥研發 Ip有限責任公司 |
Alk5 抑制劑
|
|
US20220047556A1
(en)
|
2018-12-17 |
2022-02-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sulconazole as a furin inhibitor
|
|
EP3902833A2
(en)
|
2018-12-26 |
2021-11-03 |
City of Hope |
Activatable masked anti-ctla4 binding proteins
|
|
BR112021012630A2
(pt)
|
2018-12-28 |
2022-12-13 |
Transgene Sa |
Poxvírus modificado, método para produzir o poxvírus modificado e composição
|
|
WO2020150114A1
(en)
|
2019-01-14 |
2020-07-23 |
Innate Tumor Immunity, Inc. |
Heterocyclic nlrp3 modulators, for use in the treatment of cancer
|
|
US12338228B2
(en)
|
2019-01-14 |
2025-06-24 |
Innate Tumor Immunity, Inc. |
NLRP3 modulators
|
|
JP7335341B2
(ja)
|
2019-01-14 |
2023-08-29 |
イネイト・テューマー・イミュニティ・インコーポレイテッド |
Ｎｌｒｐ３モジュレーター
|
|
EP3911416B1
(en)
|
2019-01-14 |
2024-06-12 |
Innate Tumor Immunity, Inc. |
Substituted quinazolines as nlrp3 modulators, for use in the treatment of cancer
|
|
SG11202107606VA
(en)
|
2019-01-15 |
2021-08-30 |
Inst Nat Sante Rech Med |
Mutated interleukin-34 (il-34) polypeptides and uses thereof in therapy
|
|
WO2020169472A2
(en)
|
2019-02-18 |
2020-08-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inducing phenotypic changes in macrophages
|
|
WO2020182993A1
(en)
|
2019-03-13 |
2020-09-17 |
Etherna Immunotherapies Nv |
Mrna vaccine
|
|
EP3942024A4
(en)
|
2019-03-18 |
2023-03-22 |
The Regents of the University of California |
ENHANCEMENT OF T LYMPHOCYTE ACTIVATION BY OSCILLATORY FORCES AND MODIFIED ANTIGEN-PRESENTING CELLS
|
|
JP2022527177A
(ja)
|
2019-03-28 |
2022-05-31 |
ブリストル－マイヤーズ スクイブ カンパニー |
腫瘍を処置する方法
|
|
KR20210146349A
(ko)
|
2019-03-28 |
2021-12-03 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하는 방법
|
|
JP2022527972A
(ja)
|
2019-04-02 |
2022-06-07 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
前悪性病変を有する患者において癌を予測及び予防する方法
|
|
WO2020206169A1
(en)
|
2019-04-02 |
2020-10-08 |
Kupper Thomas S |
Methods for identifying progression of a primary melanoma
|
|
WO2020208060A1
(en)
|
2019-04-09 |
2020-10-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of sk2 inhibitors in combination with immune checkpoint blockade therapy for the treatment of cancer
|
|
EP3956446A1
(en)
|
2019-04-17 |
2022-02-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for treatment of nlrp3 inflammasome mediated il-1beta dependent disorders
|
|
CA3138348A1
(en)
|
2019-05-09 |
2020-11-12 |
FUJIFILM Cellular Dynamics, Inc. |
Methods for the production of hepatocytes
|
|
TW202110431A
(zh)
|
2019-05-17 |
2021-03-16 |
美商癌症預防製藥股份有限公司 |
治療家族性腺瘤性瘜肉症之方法
|
|
EP3976832A1
(en)
|
2019-05-30 |
2022-04-06 |
Bristol-Myers Squibb Company |
Methods of identifying a subject suitable for an immuno-oncology (i-o) therapy
|
|
CN114174538A
(zh)
|
2019-05-30 |
2022-03-11 |
百时美施贵宝公司 |
适合于免疫肿瘤学疗法的多肿瘤基因特征
|
|
KR20220016157A
(ko)
|
2019-05-30 |
2022-02-08 |
브리스톨-마이어스 스큅 컴퍼니 |
세포 국재화 시그너쳐 및 조합 요법
|
|
WO2020247974A1
(en)
|
2019-06-03 |
2020-12-10 |
The University Of Chicago |
Methods and compositions for treating cancer with collagen binding drug carriers
|
|
EP3976061A4
(en)
|
2019-06-03 |
2023-07-12 |
The University of Chicago |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER WITH CANCER-TARGETING ADJUVANTS
|
|
US20210038684A1
(en)
|
2019-06-11 |
2021-02-11 |
Alkermes Pharma Ireland Limited |
Compositions and Methods for Cancer Immunotherapy
|
|
KR20220061946A
(ko)
|
2019-06-27 |
2022-05-13 |
이더알엔에이 이뮤노테라피스 엔브이 |
병용 요법
|
|
US20220257796A1
(en)
|
2019-07-02 |
2022-08-18 |
Fred Hutchinson Cancer Research Center |
Recombinant ad35 vectors and related gene therapy improvements
|
|
CA3145347A1
(en)
|
2019-07-15 |
2021-01-21 |
Intervet International B.V. |
Caninized antibodies to human and canine ctla-4
|
|
WO2021009187A1
(en)
|
2019-07-15 |
2021-01-21 |
Intervet International B.V. |
Caninized antibodies against canine ctla-4
|
|
JPWO2021024742A1
(Direct)
*
|
2019-08-06 |
2021-02-11 |
|
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
WO2021055627A1
(en)
|
2019-09-17 |
2021-03-25 |
Bial- Biotech Investments, Inc. |
Substituted n-heterocyclic carboxamides as acid ceramidase inhibitors and their use as medicaments
|
|
JP2022549228A
(ja)
|
2019-09-17 |
2022-11-24 |
バイアル－アールアンドディー インベストメンツ ソシエダッド アノニマ |
置換イミダゾールカルボキサミド及び医学的疾患の治療におけるそれらの使用
|
|
AU2020351178A1
(en)
|
2019-09-17 |
2022-03-17 |
Bial-R&D Investments, S.A. |
Substituted, saturated and unsaturated N-heterocyclic carboxamides and related compounds for their use in the treatment of medical disorders
|
|
EP4031575A1
(en)
|
2019-09-19 |
2022-07-27 |
Bristol-Myers Squibb Company |
Antibodies binding to vista at acidic ph
|
|
WO2021055994A1
(en)
|
2019-09-22 |
2021-03-25 |
Bristol-Myers Squibb Company |
Quantitative spatial profiling for lag-3 antagonist therapy
|
|
WO2021061789A1
(en)
|
2019-09-23 |
2021-04-01 |
The Regents Of The University Of Michigan |
Compositions and methods for increasing the efficacy of immunotherapies and vaccines
|
|
MX2022003719A
(es)
|
2019-09-25 |
2022-04-26 |
Surface Oncology Inc |
Anticuerpos anti-il-27 y sus usos.
|
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
|
CA3157024A1
(en)
|
2019-10-03 |
2021-04-08 |
Xencor, Inc. |
Targeted il-12 heterodimeric fc-fusion proteins
|
|
EP4037710A1
(en)
|
2019-10-04 |
2022-08-10 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and pharmaceutical composition for the treatment of ovarian cancer, breast cancer or pancreatic cancer
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
BR112022007632A2
(pt)
|
2019-10-25 |
2022-07-12 |
Daiichi Sankyo Co Ltd |
Composição farmacêutica e preparação de kit para tratamento de câncer, e, métodos para tratamento de câncer e de um paciente com câncer
|
|
WO2021087458A2
(en)
|
2019-11-02 |
2021-05-06 |
Board Of Regents, The University Of Texas System |
Targeting nonsense-mediated decay to activate p53 pathway for the treatment of cancer
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
JP2022553851A
(ja)
|
2019-11-08 |
2022-12-26 |
ブリストル－マイヤーズ スクイブ カンパニー |
黒色腫の処置のためのｌａｇ－３アンタゴニスト
|
|
IL293084A
(en)
|
2019-11-22 |
2022-07-01 |
Theravance Biopharma R& D Ip Llc |
Substituted 1,5-naphthyridines or quinolines as alk5 inhibitors
|
|
JPWO2021106978A1
(Direct)
|
2019-11-27 |
2021-06-03 |
|
|
|
WO2021113644A1
(en)
|
2019-12-05 |
2021-06-10 |
Multivir Inc. |
Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer
|
|
CA3158532A1
(en)
|
2019-12-19 |
2021-06-24 |
Susan Wee |
Combinations of dgk inhibitors and checkpoint antagonists
|
|
EP4082570A4
(en)
|
2019-12-27 |
2023-09-13 |
Chugai Seiyaku Kabushiki Kaisha |
ANTI-CTLA-4 ANTIBODIES AND USE THEREOF
|
|
EP4087922A4
(en)
|
2020-01-07 |
2024-01-10 |
Board of Regents, The University of Texas System |
HUMAN ADENOSINE/METHYLTHIOADENOSINE DEPLETING ENZYME VARIANTS FOR CANCER TREATMENT
|
|
KR20220127848A
(ko)
|
2020-01-10 |
2022-09-20 |
인네이트 튜머 이뮤니티, 인코포레이티드 |
Nlrp3 조정제
|
|
CA3167027A1
(en)
|
2020-02-05 |
2021-08-12 |
Larimar Therapeutics, Inc. |
Tat peptide binding proteins and uses thereof
|
|
US20230087600A1
(en)
|
2020-02-06 |
2023-03-23 |
Bristol-Myers Squibb Company |
Il-10 and uses thereof
|
|
WO2021167908A1
(en)
|
2020-02-17 |
2021-08-26 |
Board Of Regents, The University Of Texas System |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
|
JP2023514957A
(ja)
|
2020-02-28 |
2023-04-12 |
オレガ・バイオテック |
Ｃｔｌａ４阻害剤及びｉｌ－１７ｂ阻害剤に基づく複合療法
|
|
AU2021357520A1
(en)
|
2020-03-05 |
2022-09-29 |
Neotx Therapeutics Ltd. |
Methods and compositions for treating cancer with immune cells
|
|
EP4118118A1
(en)
|
2020-03-09 |
2023-01-18 |
Bristol-Myers Squibb Company |
Antibodies to cd40 with enhanced agonist activity
|
|
US12091681B2
(en)
|
2020-03-27 |
2024-09-17 |
Mendus B.V. |
Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
|
|
WO2021203131A1
(en)
|
2020-03-31 |
2021-10-07 |
Theravance Biopharma R&D Ip, Llc |
Substituted pyrimidines and methods of use
|
|
US20230272056A1
(en)
|
2020-04-09 |
2023-08-31 |
Merck Sharp & Dohme Llc |
Affinity matured anti-lap antibodies and uses thereof
|
|
EP4136459A1
(en)
|
2020-04-13 |
2023-02-22 |
Abbott Laboratories |
Methods, complexes and kits for detecting or determining an amount of a ss-coronavirus antibody in a sample
|
|
WO2021216670A1
(en)
|
2020-04-21 |
2021-10-28 |
University Of Rochester |
Inhibitors of human epididymus protein 4
|
|
BR112022021020A2
(pt)
|
2020-04-22 |
2023-02-14 |
Iovance Biotherapeutics Inc |
Método de fabricação de um produto de terapia celular, métodos de tratamento do paciente com o produto de terapia celular de expansão e fabricado, e, método de fabricação de um produto de terapia celular
|
|
WO2021231798A1
(en)
|
2020-05-13 |
2021-11-18 |
Disc Medicine, Inc. |
Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
|
|
JP2023525085A
(ja)
|
2020-05-13 |
2023-06-14 |
アダジーン アーゲー |
がんを治療するための組成物および方法
|
|
WO2021231732A1
(en)
|
2020-05-15 |
2021-11-18 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
|
TW202208418A
(zh)
|
2020-05-21 |
2022-03-01 |
美國德州系統大學評議委員會 |
具有vgll1特異性之t細胞受體及其用途
|
|
US20230235080A1
(en)
|
2020-06-03 |
2023-07-27 |
Bionecure Therapeutics, Inc. |
Trophoblast cell-surface antigen-2 (trop-2) antibodies
|
|
CA3169518A1
(en)
|
2020-06-03 |
2021-12-09 |
Mv Biotherapeutics Sa |
Combination of an atp-hydrolyzing enzyme and an immune checkpoint modulator and uses thereof
|
|
WO2021247836A1
(en)
|
2020-06-03 |
2021-12-09 |
Board Of Regents, The University Of Texas System |
Methods for targeting shp-2 to overcome resistance
|
|
JP2023530275A
(ja)
|
2020-06-10 |
2023-07-14 |
セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー |
Ａｌｋ５阻害剤として有用なナフチリジン誘導体
|
|
US20230293530A1
(en)
|
2020-06-24 |
2023-09-21 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
|
JP2023531537A
(ja)
|
2020-06-30 |
2023-07-24 |
メンドゥス・ベスローテン・フェンノートシャップ |
卵巣癌ワクチンでの白血病由来細胞の使用
|
|
WO2022003156A1
(en)
|
2020-07-02 |
2022-01-06 |
Oncurious Nv |
Ccr8 non-blocking binders
|
|
CA3184940A1
(en)
|
2020-07-07 |
2022-01-13 |
Jennifer Donglan WU |
Mic antibodies and binding agents and methods of using the same
|
|
CU20230001A7
(es)
|
2020-07-07 |
2023-09-07 |
BioNTech SE |
Arn terapéutico para el cáncer positivo para vph
|
|
US20230295146A1
(en)
|
2020-07-24 |
2023-09-21 |
The University Of Rochester |
Inhibitors of interleukin-1 receptor-associated kinases 1 and 4
|
|
WO2022020636A2
(en)
|
2020-07-24 |
2022-01-27 |
Amgen Inc. |
Immunogens derived from sars-cov2 spike protein
|
|
US20220043000A1
(en)
|
2020-08-04 |
2022-02-10 |
Abbott Laboratories |
Methods and kits for detecting sars-cov-2 protein in a sample
|
|
CN112359052B
(zh)
*
|
2020-08-20 |
2023-01-03 |
山东兴瑞生物科技有限公司 |
抗EpCAM嵌合抗原受体的编码基因、制备方法、具有该基因的质粒、免疫细胞及其应用
|
|
EP4204095A1
(en)
|
2020-08-28 |
2023-07-05 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hepatocellular carcinoma
|
|
WO2022047412A1
(en)
|
2020-08-31 |
2022-03-03 |
Bristol-Myers Squibb Company |
Cell localization signature and immunotherapy
|
|
EP4232019A1
(en)
|
2020-10-23 |
2023-08-30 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for lung cancer
|
|
CA3200661A1
(en)
|
2020-11-05 |
2022-05-12 |
Board Of Regents, The University Of Texas System |
Engineered t cell receptors targeting egfr antigens and methods of use
|
|
IL302728A
(en)
|
2020-11-13 |
2023-07-01 |
Catamaran Bio Inc |
Genetically modified natural killer cells and methods of use thereof
|
|
EP4251645A1
(en)
|
2020-11-25 |
2023-10-04 |
Catamaran Bio, Inc. |
Cellular therapeutics engineered with signal modulators and methods of use thereof
|
|
WO2023102384A1
(en)
|
2021-11-30 |
2023-06-08 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
WO2022119841A1
(en)
|
2020-12-01 |
2022-06-09 |
Abbott Laboratories |
Use of one or more biomarkers to determine traumatic brain injury (tbi) in a subject having received a head computerized tomography scan that is negative for a tbi
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
PH12023500013A1
(en)
|
2020-12-04 |
2024-03-11 |
Tidal Therapeutics Inc |
Ionizable cationic lipids and lipi nanoparticles, and methods of synthesis and use thereof
|
|
WO2022121966A1
(en)
*
|
2020-12-10 |
2022-06-16 |
Wuxi Biologics (Shanghai) Co., Ltd. |
An antibody against p-cadherin and uses thereof
|
|
WO2022130206A1
(en)
|
2020-12-16 |
2022-06-23 |
Pfizer Inc. |
TGFβr1 INHIBITOR COMBINATION THERAPIES
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性ｒｎａ
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
WO2022136647A1
(en)
|
2020-12-24 |
2022-06-30 |
Oncurious Nv |
Human ccr8 binders
|
|
EP4267621A1
(en)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Murine cross-reactive human ccr8 binders
|
|
WO2022136649A1
(en)
|
2020-12-24 |
2022-06-30 |
Oncurious Nv |
Non-blocking human ccr8 binders
|
|
US20220233693A1
(en)
|
2020-12-28 |
2022-07-28 |
Bristol-Myers Squibb Company |
Antibody Compositions and Methods of Use Thereof
|
|
AU2021416156A1
(en)
|
2020-12-28 |
2023-06-22 |
Bristol-Myers Squibb Company |
Methods of treating tumors
|
|
WO2022147147A1
(en)
|
2020-12-30 |
2022-07-07 |
Abbott Laboratories |
Methods for determining sars-cov-2 antigen and anti-sars-cov-2 antibody in a sample
|
|
WO2022159492A1
(en)
|
2021-01-19 |
2022-07-28 |
William Marsh Rice University |
Bone-specific delivery of polypeptides
|
|
CA3203705A1
(en)
|
2021-01-22 |
2022-07-28 |
Erik Hans MANTING |
Methods of tumor vaccination
|
|
CA3210196A1
(en)
|
2021-01-29 |
2022-08-04 |
Board Of Regents, The University Of Texas System |
Methods of treating cancer with kinase inhibitors
|
|
WO2022190058A1
(en)
|
2021-03-12 |
2022-09-15 |
Dcprime B.V. |
Methods of vaccination and use of cd47 blockade
|
|
US20240376224A1
(en)
|
2021-04-02 |
2024-11-14 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
|
EP4070799A1
(en)
|
2021-04-08 |
2022-10-12 |
Nuvamid SA |
Compositions for the improvement of sport performance
|
|
WO2022216979A1
(en)
|
2021-04-08 |
2022-10-13 |
Board Of Regents, The University Of Texas System |
Compounds and methods for theranostic targeting of parp activity
|
|
CN117279664A
(zh)
|
2021-04-10 |
2023-12-22 |
普方生物制药美国公司 |
Folr1结合剂、其偶联物及其使用方法
|
|
EP4079311B1
(en)
|
2021-04-20 |
2025-10-01 |
Nuvamid SA |
Nmn and derivatives for use in the treatment of depression and/or anxiety in patients having a form of parkinsonism
|
|
EP4079310A1
(en)
|
2021-04-20 |
2022-10-26 |
Nuvamid SA |
Nmn and derivatives for its use in the treatment of alpha-synucleinopathies
|
|
WO2022223622A1
(en)
|
2021-04-20 |
2022-10-27 |
Institut Curie |
Compositions and methods for use in immunotherapy
|
|
WO2022226317A1
(en)
|
2021-04-23 |
2022-10-27 |
Profoundbio Us Co. |
Anti-cd70 antibodies, conjugates thereof and methods of using the same
|
|
US20220381796A1
(en)
|
2021-05-18 |
2022-12-01 |
Abbott Laboratories |
Methods of evaluating brain injury in a pediatric subject
|
|
WO2022251359A1
(en)
|
2021-05-26 |
2022-12-01 |
Theravance Biopharma R&D Ip, Llc |
Bicyclic inhibitors of alk5 and methods of use
|
|
BR112023022097A2
(pt)
|
2021-06-07 |
2023-12-19 |
Agonox Inc |
Cxcr5, pd-1 e icos expressando células t cd4 reativas de tumor e seu uso
|
|
CA3222291A1
(en)
|
2021-06-14 |
2022-12-22 |
Jaime MARINO |
Methods of diagnosing or aiding in diagnosis of brain injury caused by acoustic energy, electromagnetic energy, an over pressurization wave, and/or blast wind
|
|
AR126236A1
(es)
|
2021-06-25 |
2023-10-04 |
Chugai Pharmaceutical Co Ltd |
Uso del anticuerpo anti-ctla-4
|
|
US12448451B2
(en)
|
2021-06-25 |
2025-10-21 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-CTLA-4 antibody and use thereof
|
|
EP4361273A4
(en)
|
2021-06-25 |
2025-03-05 |
Chugai Seiyaku Kabushiki Kaisha |
ANTI-CTLA-4 ANTIBODIES
|
|
US20240316005A1
(en)
|
2021-07-05 |
2024-09-26 |
Institut National de la Santé et de la Recherche Médicale |
Gene signatures for predicting survival time in patients suffering from renal cell carcinoma
|
|
MX2024000674A
(es)
|
2021-07-13 |
2024-02-07 |
BioNTech SE |
Agentes de union multiespecificos contra cd40 y cd137 en terapia de combinacion.
|
|
EP4380967A1
(en)
|
2021-08-04 |
2024-06-12 |
The Regents of the University of Colorado, a body corporate |
Lat activating chimeric antigen receptor t cells and methods of use thereof
|
|
IL310662A
(en)
|
2021-08-23 |
2024-04-01 |
Immunitas Therapeutics Inc |
Anti-CD161 antibodies and their uses
|
|
CN118715440A
(zh)
|
2021-08-31 |
2024-09-27 |
雅培实验室 |
诊断脑损伤的方法和系统
|
|
WO2023034777A1
(en)
|
2021-08-31 |
2023-03-09 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
|
AU2022354059A1
(en)
|
2021-09-30 |
2024-03-28 |
Abbott Laboratories |
Methods and systems of diagnosing brain injury
|
|
IL311790A
(en)
|
2021-10-05 |
2024-05-01 |
Chang Hao Ming |
Natural killer cells and methods of use thereof
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
IL311837A
(en)
|
2021-10-20 |
2024-05-01 |
Takeda Pharmaceuticals Co |
Compositions targeting bcma and methods of use thereof
|
|
WO2023076880A1
(en)
|
2021-10-25 |
2023-05-04 |
Board Of Regents, The University Of Texas System |
Foxo1-targeted therapy for the treatment of cancer
|
|
KR20240099362A
(ko)
|
2021-10-29 |
2024-06-28 |
브리스톨-마이어스 스큅 컴퍼니 |
혈액암에 대한 lag-3 길항제 요법
|
|
CA3238167A1
(en)
|
2021-11-19 |
2023-05-25 |
Maria Leia Smith |
Gpc3 binding agents, conjugates thereof and methods of using the same
|
|
WO2023097024A1
(en)
*
|
2021-11-24 |
2023-06-01 |
Dana-Farber Cancer Institute, Inc. |
Antibodies against ctla-4 and methods of use thereof
|
|
CA3240822A1
(en)
|
2021-12-17 |
2023-06-22 |
Tony Lee |
Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
|
|
TW202332687A
(zh)
|
2021-12-23 |
2023-08-16 |
比利時商ｅＴｈｅＲＮＡ免疫治療公司 |
免疫刺激性mrna組成物及其用途
|
|
WO2023147371A1
(en)
|
2022-01-26 |
2023-08-03 |
Bristol-Myers Squibb Company |
Combination therapy for hepatocellular carcinoma
|
|
KR20240139074A
(ko)
|
2022-02-04 |
2024-09-20 |
애벗트 라보라토리이즈 |
샘플에서 유비퀴틴 카르복시-말단 히드롤라제 l1 및/또는 신경교 섬유성 산성 단백질의 존재를 검출하거나 또는 그의 양을 측정하기 위한 측면 유동 방법, 검정 및 기기
|
|
CN118765284A
(zh)
|
2022-02-25 |
2024-10-11 |
百时美施贵宝公司 |
结直肠癌的组合疗法
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
WO2023170606A1
(en)
|
2022-03-08 |
2023-09-14 |
Alentis Therapeutics Ag |
Use of anti-claudin-1 antibodies to increase t cell availability
|
|
MX2024011278A
(es)
|
2022-03-15 |
2024-09-25 |
Compugen Ltd |
Anticuerpos antagonistas de il-18bp y su uso en monoterapia y terapia de combinacion en el tratamiento del cancer.
|
|
JPWO2023176881A1
(Direct)
|
2022-03-16 |
2023-09-21 |
|
|
|
US20250206775A1
(en)
|
2022-03-18 |
2025-06-26 |
Bristol-Myers Squibb Company |
Methods of isolating polypeptides
|
|
WO2023196987A1
(en)
|
2022-04-07 |
2023-10-12 |
Bristol-Myers Squibb Company |
Methods of treating tumor
|
|
EP4507704A1
(en)
|
2022-04-15 |
2025-02-19 |
Iovance Biotherapeutics, Inc. |
Til expansion processes using specific cytokine combinations and/or akti treatment
|
|
EP4514382A1
(en)
|
2022-04-28 |
2025-03-05 |
Musc Foundation for Research Development |
Chimeric antigen receptor modified regulatory t cells for treating cancer
|
|
WO2023213764A1
(en)
|
2022-05-02 |
2023-11-09 |
Transgene |
Fusion polypeptide comprising an anti-pd-l1 sdab and a member of the tnfsf
|
|
WO2023213763A1
(en)
|
2022-05-02 |
2023-11-09 |
Transgene |
Poxvirus encoding a binding agent comprising an anti- pd-l1 sdab
|
|
CN119255825A
(zh)
|
2022-05-24 |
2025-01-03 |
第一三共株式会社 |
抗-cdh6抗体-药物缀合物的剂量方案
|
|
EP4531916A1
(en)
|
2022-06-02 |
2025-04-09 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
EP4536627A1
(en)
|
2022-06-08 |
2025-04-16 |
Tidal Therapeutics, Inc. |
Ionizable cationic lipids and lipid nanoparticles, and methods of synthesis and use thereof
|
|
GB202209518D0
(en)
|
2022-06-29 |
2022-08-10 |
Snipr Biome Aps |
Treating & preventing E coli infections
|
|
CN120167040A
(zh)
|
2022-06-29 |
2025-06-17 |
雅培实验室 |
用于确定生物样本中的gfap的磁性定点照护型系统和测定
|
|
EP4547705A1
(en)
|
2022-07-01 |
2025-05-07 |
Transgene |
Fusion protein comprising a surfactant-protein-d and a member of the tnfsf
|
|
TW202412859A
(zh)
|
2022-07-28 |
2024-04-01 |
英商阿斯特捷利康英國股份有限公司 |
抗體-藥物結合物及雙特異性檢查點抑制劑之組合
|
|
WO2024028794A1
(en)
|
2022-08-02 |
2024-02-08 |
Temple Therapeutics BV |
Methods for treating endometrial and ovarian hyperproliferative disorders
|
|
WO2024052356A1
(en)
|
2022-09-06 |
2024-03-14 |
Institut National de la Santé et de la Recherche Médicale |
Inhibitors of the ceramide metabolic pathway for overcoming immunotherapy resistance in cancer
|
|
EP4587842A1
(en)
|
2022-09-15 |
2025-07-23 |
Abbott Laboratories |
Biomarkers and methods for differentiating between mild and supermild traumatic brain injury
|
|
EP4605422A2
(en)
|
2022-10-20 |
2025-08-27 |
Repertoire Immune Medicines, Inc. |
Cd8 t cell targeted il2
|
|
EP4623072A2
(en)
|
2022-11-21 |
2025-10-01 |
Iovance Biotherapeutics, Inc. |
Two-dimensional processes for the expansion of tumor infiltrating lymphocytes and therapies therefrom
|
|
WO2024126457A1
(en)
|
2022-12-14 |
2024-06-20 |
Astellas Pharma Europe Bv |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and immune checkpoint inhibitors
|
|
CN120731228A
(zh)
|
2022-12-21 |
2025-09-30 |
百时美施贵宝公司 |
肺癌的组合疗法
|
|
EP4658687A1
(en)
|
2023-01-31 |
2025-12-10 |
University of Rochester |
Immune checkpoint blockade therapy for treating staphylococcus aureus infections
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
IL320593A
(en)
|
2023-03-29 |
2025-07-01 |
Daiichi Sankyo Co Ltd |
Anti-CD25 antibody and anti-CD25 antibody conjugate
|
|
WO2024211475A1
(en)
|
2023-04-04 |
2024-10-10 |
Abbott Laboratories |
Use of biomarkers to determine whether a subject has sustained, may have sustained or is suspected of sustaining a subacute acquired brain injury (abi)
|
|
WO2024213767A1
(en)
|
2023-04-14 |
2024-10-17 |
Institut National de la Santé et de la Recherche Médicale |
Engraftment of mesenchymal stromal cells engineered to stimulate immune infiltration in tumors
|
|
WO2024226969A1
(en)
|
2023-04-28 |
2024-10-31 |
Abbott Point Of Care Inc. |
Improved assays, cartridges, and kits for detection of biomarkers, including brain injury biomarkers
|
|
WO2024261302A1
(en)
|
2023-06-22 |
2024-12-26 |
Institut National de la Santé et de la Recherche Médicale |
Nlrp3 inhibitors, pak1/2 inhibitors and/or caspase 1 inhibitors for use in the treatment of rac2 monogenic disorders
|
|
TW202515608A
(zh)
|
2023-06-26 |
2025-04-16 |
以色列商坎布根有限公司 |
Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途
|
|
WO2025003193A1
(en)
|
2023-06-26 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Sertraline and indatraline for disrupting intracellular cholesterol trafficking and subsequently inducing lysosomal damage and anti-tumor immunity
|
|
EP4484445A1
(en)
|
2023-06-26 |
2025-01-01 |
Universität zu Köln |
Hcmv neutralizing antibodies
|
|
WO2025012417A1
(en)
|
2023-07-13 |
2025-01-16 |
Institut National de la Santé et de la Recherche Médicale |
Anti-neurotensin long fragment and anti-neuromedin n long fragment antibodies and uses thereof
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
WO2025050009A2
(en)
|
2023-09-01 |
2025-03-06 |
Children's Hospital Medical Center |
Identification of targets for immunotherapy in melanoma using splicing-derived neoantigens
|
|
EP4590715A1
(en)
|
2023-09-21 |
2025-07-30 |
Domain Therapeutics |
Anti-ccr8 monoclonal antibodies and their therapeutic use
|
|
WO2025061993A1
(en)
|
2023-09-21 |
2025-03-27 |
Domain Therapeutics |
Anti-ccr8 monoclonal antibodies and their therapeutic use
|
|
WO2025121445A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
EP4574165A1
(en)
|
2023-12-21 |
2025-06-25 |
Egle Therapeutics |
Immunocytokine for cancer treatment
|
|
WO2025133175A1
(en)
|
2023-12-21 |
2025-06-26 |
Egle Therapeutics |
Immunocytokine for cancer treatment
|
|
WO2025145207A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg-depleting agent
|
|
WO2025174825A2
(en)
|
2024-02-12 |
2025-08-21 |
Aera Therapeutics, Inc. |
Delivery compositions
|
|
US20250361320A1
(en)
|
2024-02-27 |
2025-11-27 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
EP4658320A1
(en)
|
2024-02-27 |
2025-12-10 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibody drug conjugates
|
|
WO2025202222A1
(en)
|
2024-03-25 |
2025-10-02 |
Institut National de la Santé et de la Recherche Médicale |
Therapeutic use of sting and tlrs agonists to induce p16 expression in immune cells
|
|
WO2025210175A1
(en)
|
2024-04-04 |
2025-10-09 |
Centre National De La Recherche Scientifique |
Mutant csf-1r extracellular domain fusion molecules and therapeutic uses thereof
|
|
WO2025217094A1
(en)
|
2024-04-08 |
2025-10-16 |
University Of Rochester |
Interleukin receptor-associated kinase (irak) protac degraders and medical use thereof
|
|
WO2025217096A1
(en)
|
2024-04-08 |
2025-10-16 |
University Of Rochester |
Inhibitors of leucine-rich repeat kinase 2 (lrrk2) and medical uses thereof
|
|
WO2025245489A1
(en)
|
2024-05-24 |
2025-11-27 |
Bristol-Myers Squibb Company |
Treatment of tumors in subjects having fgl-1 positive samples
|
|
WO2025248505A1
(en)
|
2024-05-31 |
2025-12-04 |
Wayne State University |
Methods for treating endometrial and ovarian hyperproliferative disorders
|