RU2011100779A - Ингалятор для сухого порошка и система для доставки лекарственных средств - Google Patents
Ингалятор для сухого порошка и система для доставки лекарственных средств Download PDFInfo
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- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
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- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
- A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
- A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
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Abstract
1. Картридж для сухого порошкообразного медикамента для ингалятора, содержащий: ! а) верхнюю часть картриджа и ! в) нижнюю часть картриджа, определяющую внутренний объем; ! где верхняя часть картриджа имеет обратную поверхность, которая проходит поверх нижней части картриджа; причем указанная обратная поверхность конфигурирована для зацепления с нижней частью картриджа и имеет область для герметизации внутреннего объема и область для экспонирования внутреннего объема для воздуха из окружающей среды. ! 2. Картридж по п.1, в котором верхняя часть картриджа содержит, по меньшей мере, один распределительный порт. ! 3. Картридж по п.1 или 2, в котором верхняя часть картриджа содержит одну или более поверхностей захвата. ! 4. Картридж по п.1, в котором верхняя часть картриджа содержит одну или более ключевых поверхностей. ! 5. Картридж по п.1, в котором верхняя часть картриджа является примерно прямоугольной по форме, содержит область углубления на своей верхней поверхности и выпуклость, имеющую, по меньшей мере, один распределительный порт. ! 6. Картридж по п.1, в котором нижняя часть картриджа соединена с возможностью перемещения с обратной поверхностью и может конфигурироваться для получения положения удерживания и положения распределения или дозирования посредством перемещения относительно обратной поверхности. ! 7. Картридж по п.6, в котором нижняя часть картриджа может перемещаться посредством поступательного или посредством вращательного движения. ! 8. Картридж по п.6 или 7, в котором, в положении удерживания, нижняя поверхность герметизирует внутренний объем нижней части картриджа с формированием полости, конфигу�
Claims (20)
1. Картридж для сухого порошкообразного медикамента для ингалятора, содержащий:
а) верхнюю часть картриджа и
в) нижнюю часть картриджа, определяющую внутренний объем;
где верхняя часть картриджа имеет обратную поверхность, которая проходит поверх нижней части картриджа; причем указанная обратная поверхность конфигурирована для зацепления с нижней частью картриджа и имеет область для герметизации внутреннего объема и область для экспонирования внутреннего объема для воздуха из окружающей среды.
2. Картридж по п.1, в котором верхняя часть картриджа содержит, по меньшей мере, один распределительный порт.
3. Картридж по п.1 или 2, в котором верхняя часть картриджа содержит одну или более поверхностей захвата.
4. Картридж по п.1, в котором верхняя часть картриджа содержит одну или более ключевых поверхностей.
5. Картридж по п.1, в котором верхняя часть картриджа является примерно прямоугольной по форме, содержит область углубления на своей верхней поверхности и выпуклость, имеющую, по меньшей мере, один распределительный порт.
6. Картридж по п.1, в котором нижняя часть картриджа соединена с возможностью перемещения с обратной поверхностью и может конфигурироваться для получения положения удерживания и положения распределения или дозирования посредством перемещения относительно обратной поверхности.
7. Картридж по п.6, в котором нижняя часть картриджа может перемещаться посредством поступательного или посредством вращательного движения.
8. Картридж по п.6 или 7, в котором, в положении удерживания, нижняя поверхность герметизирует внутренний объем нижней части картриджа с формированием полости, конфигурируемой для содержания в ней медикамента и ограничения потока воздуха, поступающего во внутренний объем нижней части картриджа.
9. Картридж по п.6 или 7, в котором, в положении удерживания или дозирования указанный, по меньшей мере, один распределительный порт расположен поверх внутреннего объема нижней части картриджа и верхней части картриджа, и нижняя часть картриджа формирует, по меньшей мере, один входной порт, который делает возможным поток воздуха во внутренний объем нижней части картриджа в ответ на разность давлений.
10. Картридж по п.6 или 7, в котором, в положении распределения или дозирования указанный, по меньшей мере, один распределительный порт обеспечивает сопротивление потоку.
11. Картридж по п.6 или 7, в котором, в положении удерживания или дозирования указанный, по меньшей мере, один входной порт конфигурирован для направления части потока воздуха во внутренний объем для циркуляции потока вокруг внутреннего объема.
12. Картридж по п.6 или 7, в котором, в положении удерживания или дозирования указанный, по меньшей мере, один входной порт конфигурирован для направления части потока воздуха к указанному, по меньшей мере, одному распределительному порту в ответ на разность давлений.
13. Картридж по п.1, в котором картридж сформирован из полимерного материала.
14. Картридж по п.13, в котором полимерный материал представляет собой термоформируемый пластик, выбранный из группы, состоящей из полипропилена, сополимера циклического олефина, нейлона и полиэтилена.
15. Картридж по п.13 или 14, в котором полимерный материал представляет собой полимер полиэтилена высокой плотности.
16. Картридж по п.9, в котором один или более входных портов имеют общую площадь поперечного сечения указанного, которая больше чем общая площадь поперечного сечения указанного, по меньшей мере, одного распределительного порта.
17. Картридж по п.2, в котором площадь поперечного сечения указанного, по меньшей мере, одного распределительного порта находится в пределах от 0,05 см2 примерно до 0,25 см2.
18. Картридж по п.1, в котором в котором верхняя часть картриджа и нижняя часть картриджа могут конфигурироваться для получения положения выбрасывания.
19. Система ингаляции, содержащая:
ингалятор для сухого порошка и
картридж по пп.1-18,
где, в положении распределения или дозирования, картридж и ингалятор формируют жесткий проход для потока, для протекания газа через картридж, и этот жесткий проход для потока является по существу перпендикулярным проходу для потока в мундштуке.
20. Система ингаляции по п.19, дополнительно содержащая оболочку, в которой должен устанавливаться картридж и должны определяться два пути для потоков.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6155108P | 2008-06-13 | 2008-06-13 | |
US61/061,551 | 2008-06-13 | ||
US15750609P | 2009-03-04 | 2009-03-04 | |
US61/157,506 | 2009-03-04 | ||
PCT/US2009/047281 WO2009152477A2 (en) | 2008-06-13 | 2009-06-12 | A dry powder inhaler and system for drug delivery |
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Application Number | Title | Priority Date | Filing Date |
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RU2012136220A Division RU2608439C2 (ru) | 2008-06-13 | 2009-06-12 | Ингалятор для сухого порошка и система для доставки лекарственных средств |
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Publication Number | Publication Date |
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RU2011100779A true RU2011100779A (ru) | 2012-07-20 |
RU2468832C2 RU2468832C2 (ru) | 2012-12-10 |
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Application Number | Title | Priority Date | Filing Date |
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RU2012136220A RU2608439C2 (ru) | 2008-06-13 | 2009-06-12 | Ингалятор для сухого порошка и система для доставки лекарственных средств |
RU2011100779/14A RU2468832C2 (ru) | 2008-06-13 | 2009-06-12 | Ингалятор для сухого порошка и система для доставки лекарственных средств |
RU2016147947A RU2731107C9 (ru) | 2008-06-13 | 2016-12-07 | Ингалятор для сухого порошка и система для доставки лекарственных средств |
RU2020127590A RU2020127590A (ru) | 2008-06-13 | 2020-08-19 | Ингалятор для сухого порошка и система для доставки лекарственных средств |
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