ATE420630T1 - Pulverzubereitungen und verfahren zu ihrer herstellung - Google Patents

Pulverzubereitungen und verfahren zu ihrer herstellung

Info

Publication number
ATE420630T1
ATE420630T1 AT01998330T AT01998330T ATE420630T1 AT E420630 T1 ATE420630 T1 AT E420630T1 AT 01998330 T AT01998330 T AT 01998330T AT 01998330 T AT01998330 T AT 01998330T AT E420630 T1 ATE420630 T1 AT E420630T1
Authority
AT
Austria
Prior art keywords
production
particle diameter
powder preparations
formulation
medicament
Prior art date
Application number
AT01998330T
Other languages
English (en)
Inventor
Satomi Onoue
Kousuke Endo
Kazuhisa Kashimoto
Original Assignee
Itoham Foods Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2001088337A external-priority patent/JP2002284703A/ja
Application filed by Itoham Foods Inc filed Critical Itoham Foods Inc
Priority claimed from JP2001364325A external-priority patent/JP4125512B2/ja
Application granted granted Critical
Publication of ATE420630T1 publication Critical patent/ATE420630T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT01998330T 2000-11-29 2001-11-29 Pulverzubereitungen und verfahren zu ihrer herstellung ATE420630T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000362704 2000-11-29
JP2001088337A JP2002284703A (ja) 2001-03-26 2001-03-26 粉末製剤
JP2001364325A JP4125512B2 (ja) 2000-11-29 2001-11-29 粉末製剤及びその製造方法

Publications (1)

Publication Number Publication Date
ATE420630T1 true ATE420630T1 (de) 2009-01-15

Family

ID=27345297

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01998330T ATE420630T1 (de) 2000-11-29 2001-11-29 Pulverzubereitungen und verfahren zu ihrer herstellung

Country Status (9)

Country Link
US (1) US20040109827A1 (de)
EP (1) EP1348428B1 (de)
KR (1) KR100587237B1 (de)
CN (1) CN100400031C (de)
AT (1) ATE420630T1 (de)
AU (2) AU2002218503B2 (de)
CA (1) CA2430318C (de)
DE (1) DE60137452D1 (de)
WO (1) WO2002043703A1 (de)

Families Citing this family (30)

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US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
HUE058227T2 (hu) 2004-04-23 2022-07-28 Cydex Pharmaceuticals Inc DPI készítmény, amely szulfoalkil-éter-ciklodextrint tartalmaz
EP1593376A1 (de) * 2004-05-04 2005-11-09 Warner-Lambert Company LLC Verbesserte Pullulankapseln
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
JP5156397B2 (ja) * 2005-02-10 2013-03-06 グラクソ グループ リミテッド 予備分級技術を用いて乳糖を製造する方法及びその乳糖から形成させた医薬製剤
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
DE102006053375A1 (de) * 2006-11-10 2008-05-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Mischung von Pulvern
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
BR112012033060A2 (pt) 2010-06-21 2018-02-27 Mannkind Corp métodos de sistema de liberação de fármaco em pó seco
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
PH12014500551A1 (en) * 2011-09-14 2014-04-21 Shionogi & Co Pharmaceutical composition for inhalation
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
JP5087182B1 (ja) * 2012-06-13 2012-11-28 クリニプロ株式会社 吸入用パウダーの製造方法
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014145720A2 (en) * 2013-03-15 2014-09-18 Antioxidant Superfoods, Inc. Fat emulsion providing taste masking for active health and wellness ingredients
CN114848614A (zh) * 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
TWI745396B (zh) 2016-07-12 2021-11-11 日商鹽野義製藥股份有限公司 吸入用醫藥組成物
WO2019102310A1 (en) * 2017-11-24 2019-05-31 Alaval (Pty) Ltd Vip formulation for management of inflammatory conditions
CN117652666B (zh) * 2023-12-12 2025-11-25 晨光生物科技集团股份有限公司 一种类胡萝卜素微胶囊及其制备方法和应用

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Publication number Priority date Publication date Assignee Title
GB9100009D0 (en) * 1991-01-02 1991-02-20 Cerestar Holding Bv Erythritol compositions
US5354934A (en) * 1993-02-04 1994-10-11 Amgen Inc. Pulmonary administration of erythropoietin
DE69431290D1 (de) * 1993-02-12 2002-10-10 Avant Immunotherapeutics Inc PULMONÄRE VERABREICHUNG DES LÖSLICHEN KOMPLEMENT-RECEPTORS TYP 1 sCR1
DK0686045T3 (da) * 1993-02-23 2001-03-05 Genentech Inc Stabilisering af med organisk opløsningsmiddel behandlede polypeptider med et hjælpestof
TW402506B (en) * 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
EP0748213B1 (de) * 1994-03-07 2004-04-14 Nektar Therapeutics Verfahren und mittel zur verabreichung von insulin über die lunge
JPH08301762A (ja) * 1995-05-12 1996-11-19 Teijin Ltd 肺癌治療剤
JPH08337532A (ja) * 1995-06-14 1996-12-24 Takeda Chem Ind Ltd 医薬組成物
KR100568436B1 (ko) * 1996-02-27 2007-04-25 데이진 가부시키가이샤 분말상경비투여조성물
US5898028A (en) * 1997-03-20 1999-04-27 Novo Nordisk A/S Method for producing powder formulation comprising an insulin
JP4266399B2 (ja) * 1997-12-04 2009-05-20 帝人株式会社 粉末状吸入用医薬品組成物
CA2387212A1 (en) * 1999-10-12 2001-04-19 Kaken Pharmaceutical Co., Ltd. Dry powder inhalation and a method for the preparation thereof

Also Published As

Publication number Publication date
AU1850302A (en) 2002-06-11
CN1486175A (zh) 2004-03-31
KR100587237B1 (ko) 2006-06-07
AU2002218503B2 (en) 2006-09-28
CN100400031C (zh) 2008-07-09
CA2430318C (en) 2009-10-27
EP1348428A4 (de) 2005-09-21
WO2002043703A1 (fr) 2002-06-06
CA2430318A1 (en) 2002-06-06
KR20030096238A (ko) 2003-12-24
EP1348428B1 (de) 2009-01-14
DE60137452D1 (de) 2009-03-05
HK1063286A1 (en) 2004-12-24
US20040109827A1 (en) 2004-06-10
EP1348428A1 (de) 2003-10-01

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