US6586006B2
(en)
|
1994-08-04 |
2003-07-01 |
Elan Drug Delivery Limited |
Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
|
US6290991B1
(en)
|
1994-12-02 |
2001-09-18 |
Quandrant Holdings Cambridge Limited |
Solid dose delivery vehicle and methods of making same
|
CZ88697A3
(en)
|
1994-09-22 |
1997-09-17 |
Quadrant Holdings Cambridge |
Composition used for re-hydration and nourishment in the course of athletic outputs and processes for preparing thereof
|
US6964771B1
(en)
*
|
1995-06-07 |
2005-11-15 |
Elan Drug Delivery Limited |
Method for stably incorporating substances within dry, foamed glass matrices
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
US6685940B2
(en)
|
1995-07-27 |
2004-02-03 |
Genentech, Inc. |
Protein formulation
|
EP2275119B1
(en)
*
|
1995-07-27 |
2013-09-25 |
Genentech, Inc. |
Stable isotonic lyophilized protein formulation
|
JP2014148555A
(ja)
*
|
1995-07-27 |
2014-08-21 |
Genentech Inc |
タンパク質の処方
|
US5762961A
(en)
*
|
1996-02-09 |
1998-06-09 |
Quadrant Holdings Cambridge Ltd. |
Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof
|
US5958455A
(en)
*
|
1996-02-09 |
1999-09-28 |
Quadrant Holdings Cambridge Ltd |
Oral solid dosage forms, methods of making same and compositions thereof
|
AUPN801296A0
(en)
*
|
1996-02-12 |
1996-03-07 |
Csl Limited |
Stabilised growth hormone formulation and method of preparation thereof
|
DE69717263T2
(de)
|
1996-03-28 |
2003-07-24 |
Takeda Chemical Industries, Ltd. |
Zubereitung mit verzögerter freisetzung und deren herstellung
|
US6632648B1
(en)
|
1996-05-14 |
2003-10-14 |
Elan Drug Delivery Limited |
Methods of terminal sterilization of fibrinogen
|
AU737664B2
(en)
*
|
1996-07-03 |
2001-08-30 |
Alza Corporation |
Non-aqueous protic peptide formulations
|
US5932547A
(en)
*
|
1996-07-03 |
1999-08-03 |
Alza Corporation |
Non-aqueous polar aprotic peptide formulations
|
US5916582A
(en)
*
|
1996-07-03 |
1999-06-29 |
Alza Corporation |
Aqueous formulations of peptides
|
US5861174A
(en)
|
1996-07-12 |
1999-01-19 |
University Technology Corporation |
Temperature sensitive gel for sustained delivery of protein drugs
|
US5981489A
(en)
*
|
1996-07-18 |
1999-11-09 |
Alza Corporation |
Non-aqueous protic peptide formulations
|
US6468782B1
(en)
*
|
1996-12-05 |
2002-10-22 |
Quadrant Healthcare (Uk) Limited |
Methods of preserving prokaryotic cells and compositions obtained thereby
|
AU7871298A
(en)
|
1996-12-20 |
1998-07-17 |
Takeda Chemical Industries Ltd. |
Method of producing a sustained-release preparation
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
US6663899B2
(en)
|
1997-06-13 |
2003-12-16 |
Genentech, Inc. |
Controlled release microencapsulated NGF formulation
|
US6991790B1
(en)
*
|
1997-06-13 |
2006-01-31 |
Genentech, Inc. |
Antibody formulation
|
US6113947A
(en)
*
|
1997-06-13 |
2000-09-05 |
Genentech, Inc. |
Controlled release microencapsulated NGF formulation
|
CN1271277A
(zh)
*
|
1997-07-18 |
2000-10-25 |
因菲米德有限公司 |
用于生物活性物质控释的生物可降解的大分子的单体
|
US20060165606A1
(en)
|
1997-09-29 |
2006-07-27 |
Nektar Therapeutics |
Pulmonary delivery particles comprising water insoluble or crystalline active agents
|
US6565885B1
(en)
|
1997-09-29 |
2003-05-20 |
Inhale Therapeutic Systems, Inc. |
Methods of spray drying pharmaceutical compositions
|
SE512663C2
(sv)
|
1997-10-23 |
2000-04-17 |
Biogram Ab |
Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
|
WO1999047174A1
(en)
*
|
1998-03-18 |
1999-09-23 |
Cambridge Biostability Limited |
Amorphous glasses for stabilising sensitive products
|
JP2002510653A
(ja)
*
|
1998-04-03 |
2002-04-09 |
カイロン コーポレイション |
緩衝剤としてコハク酸を含有する注射可能なigf処方物
|
CN1379681A
(zh)
*
|
1998-04-17 |
2002-11-13 |
安乔格尼克斯公司 |
治疗性的血管生成因子及其使用方法
|
US6284282B1
(en)
*
|
1998-04-29 |
2001-09-04 |
Genentech, Inc. |
Method of spray freeze drying proteins for pharmaceutical administration
|
US6190701B1
(en)
|
1999-03-17 |
2001-02-20 |
Peter M. Ronai |
Composition and method for stable injectable liquids
|
GB9910975D0
(en)
*
|
1999-05-13 |
1999-07-14 |
Univ Strathclyde |
Rapid dehydration of proteins
|
US6566329B1
(en)
*
|
1999-06-28 |
2003-05-20 |
Novo Nordisk A/S |
Freeze-dried preparation of human growth hormone
|
US6102896A
(en)
*
|
1999-09-08 |
2000-08-15 |
Cambridge Biostability Limited |
Disposable injector device
|
US7582311B1
(en)
|
1999-10-15 |
2009-09-01 |
Genentech, Inc. |
Injection vehicle for polymer-based formulations
|
US7651703B2
(en)
*
|
1999-10-15 |
2010-01-26 |
Genentech, Inc. |
Injection vehicle for polymer-based formulations
|
WO2001058428A1
(en)
*
|
2000-02-10 |
2001-08-16 |
Alkermes Controlled Therapeutics, Inc. |
Method of preparing a sustained release composition
|
JP4361710B2
(ja)
|
2000-04-19 |
2009-11-11 |
ジェネンテック・インコーポレーテッド |
徐放製剤
|
PT1280520E
(pt)
|
2000-05-10 |
2014-12-16 |
Novartis Ag |
Pós à base de fosfolípidos para administração de fármacos
|
US8404217B2
(en)
|
2000-05-10 |
2013-03-26 |
Novartis Ag |
Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
|
US7871598B1
(en)
|
2000-05-10 |
2011-01-18 |
Novartis Ag |
Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
|
US6653062B1
(en)
|
2000-07-26 |
2003-11-25 |
Wisconsin Alumni Research Foundation |
Preservation and storage medium for biological materials
|
KR20030038690A
(ko)
*
|
2000-08-07 |
2003-05-16 |
인헤일 테라퓨틱 시스템즈 인크. |
응집이 최소화된, 흡입성 분무 건조 4-나선 다발 단백질분말
|
US6824822B2
(en)
*
|
2001-08-31 |
2004-11-30 |
Alkermes Controlled Therapeutics Inc. Ii |
Residual solvent extraction method and microparticles produced thereby
|
ATE450253T1
(de)
*
|
2000-10-13 |
2009-12-15 |
Cambridge Biostability Ltd |
Pharmazeutische flüssige suspensionen
|
DE60137452D1
(de)
*
|
2000-11-29 |
2009-03-05 |
Itoham Foods Inc |
Pulverzubereitungen und verfahren zu ihrer herstellung
|
US20040022861A1
(en)
*
|
2001-01-30 |
2004-02-05 |
Williams Robert O. |
Process for production of nanoparticles and microparticles by spray freezing into liquid
|
DK1372729T3
(da)
*
|
2001-02-23 |
2009-06-22 |
Genentech Inc |
Nedbrydelige polymere til injektion
|
US7318931B2
(en)
*
|
2001-06-21 |
2008-01-15 |
Genentech, Inc. |
Sustained release formulation
|
GB0116074D0
(en)
*
|
2001-06-29 |
2001-08-22 |
Univ Strathclyde |
Nanoparticle structures
|
GB2404865B
(en)
*
|
2001-09-11 |
2005-09-28 |
Caretek Medical Ltd |
Novel drug delivery technology
|
US7615234B2
(en)
|
2001-09-11 |
2009-11-10 |
Glide Pharmaceutical Technologies Limited |
Drug delivery technology
|
TWI324518B
(en)
|
2001-12-19 |
2010-05-11 |
Nektar Therapeutics |
Pulmonary delivery of aminoglycosides
|
EP1493015A4
(en)
*
|
2002-04-05 |
2006-01-04 |
Powerzyme Inc |
ANALYTE DETECTOR
|
WO2003094887A1
(en)
*
|
2002-05-09 |
2003-11-20 |
Peptron Co., Ltd |
Sustained release formulation of protein and preparation method thereof
|
GB2421689B
(en)
|
2002-08-05 |
2007-03-07 |
Caretek Medical Ltd |
Drug delivery system
|
CN100444848C
(zh)
*
|
2002-09-27 |
2008-12-24 |
特里梅里斯公司 |
HIV gp41-衍生肽的改善用药的药物组合物
|
US7045552B2
(en)
*
|
2002-09-27 |
2006-05-16 |
Trimeris, Inc. |
Pharmaceutical composition for improved administration of HIV gp41-derived peptides, and its use in therapy
|
US7164005B2
(en)
*
|
2002-10-17 |
2007-01-16 |
Alkermes, Inc. |
Microencapsulation and sustained release of biologically active polypeptides
|
WO2004060310A2
(en)
*
|
2002-12-31 |
2004-07-22 |
Altus Pharmaceuticals Inc. |
Human growth hormone crystals and methods for preparing them
|
KR20050094832A
(ko)
*
|
2002-12-31 |
2005-09-28 |
알투스 파마슈티컬스 인코포레이티드 |
단백질 결정과 이온성 중합체를 함유하는 복합체
|
US20040197413A1
(en)
*
|
2003-04-04 |
2004-10-07 |
Genteric, Inc. |
Spray dry coacervation systems and methods
|
DE10320609A1
(de)
*
|
2003-05-08 |
2004-12-02 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Sprühgefriergranulate mit verbesserter Homogenität der Eigenschaftsverteilung und Verfahren zu deren Herstellung
|
US7090433B2
(en)
*
|
2003-10-07 |
2006-08-15 |
Steve Searby |
Underground cable laying apparatus
|
US20050095320A1
(en)
*
|
2003-10-29 |
2005-05-05 |
Richard Botteri |
[An Isotonic Sports Drink for Female Athletes Fortified with Iron, Calcium and Essential Vitamins for Use in Rehydration and Nutrition During Execise and Competition]
|
US20050100636A1
(en)
*
|
2003-11-10 |
2005-05-12 |
Megan Botteri |
[A Low-Calorie Sports Drink For Physically Active Women That is Fortified with Iron, Calcium and Essential Vitamins for Use in Rehydration and Replacing Electrolytes Lost During Periods of Physical Activity]
|
KR20070006708A
(ko)
*
|
2004-01-07 |
2007-01-11 |
트라이머리스 인코퍼레이티드 |
HIV gp41 HR2-유래된 합성 펩티드 및 인간 면역결핍바이러스의 전염을 저해하는 치료에서 이들의 용도
|
US8617613B2
(en)
*
|
2004-04-15 |
2013-12-31 |
Alkermes Pharma Ireland Limited |
Polymer-based sustained release device
|
US7456254B2
(en)
*
|
2004-04-15 |
2008-11-25 |
Alkermes, Inc. |
Polymer-based sustained release device
|
JP2007277094A
(ja)
*
|
2004-06-29 |
2007-10-25 |
Chemo Sero Therapeut Res Inst |
改変ダニ主要アレルゲン含有医薬組成物
|
US7133638B2
(en)
*
|
2004-11-18 |
2006-11-07 |
Xerox Corporation |
Scanning method and an image-processing device including the same
|
US11246913B2
(en)
|
2005-02-03 |
2022-02-15 |
Intarcia Therapeutics, Inc. |
Suspension formulation comprising an insulinotropic peptide
|
GB2422784A
(en)
*
|
2005-02-07 |
2006-08-09 |
Caretek Medical Ltd |
Disposable assembly comprising a needle or stylet
|
BRPI0608815B1
(pt)
*
|
2005-03-08 |
2021-10-13 |
Pfizer Products Inc |
Composições de anticorpo anti-ctla-4
|
CN100336557C
(zh)
*
|
2005-05-11 |
2007-09-12 |
北京双鹭药业股份有限公司 |
一种生长抑素的水溶液制剂、其制备方法及应用
|
CN100337684C
(zh)
*
|
2005-05-11 |
2007-09-19 |
北京双鹭药业股份有限公司 |
一种胸腺五肽的水溶液制剂、其制备方法及应用
|
CN100342909C
(zh)
*
|
2005-05-11 |
2007-10-17 |
北京双鹭药业股份有限公司 |
一种胸腺素α1的水溶液制剂、其制备方法及应用
|
GB0517688D0
(en)
*
|
2005-08-31 |
2005-10-05 |
Cambridge Biostability Ltd |
Improvements in the stabilisation of biological materials
|
US9309316B2
(en)
*
|
2005-12-20 |
2016-04-12 |
Bristol-Myers Squibb Company |
Stable subcutaneous protein formulations and uses thereof
|
PT1962886E
(pt)
*
|
2005-12-20 |
2014-01-07 |
Bristol Myers Squibb Co |
Formulações de proteína estáveis
|
AU2006330833A1
(en)
*
|
2005-12-23 |
2007-07-05 |
Altus Pharmaceuticals Inc. |
Compositions comprising polycation-complexed protein crystals and methods of treatment using them
|
TWI341844B
(en)
|
2006-02-02 |
2011-05-11 |
Trimeris Inc |
Hiv fusion inhibitor peptides with improved biological properties
|
EP2004753B1
(en)
*
|
2006-03-13 |
2010-01-13 |
NATURIN GmbH & CO. |
Collagen powder and collagen-based thermoplastic composition por preparing conformed articles
|
DK2049081T3
(da)
|
2006-08-09 |
2013-02-25 |
Intarcia Therapeutics Inc |
Osmotiske leveringssystemer og stempelarrangementer
|
WO2008118133A2
(en)
|
2006-09-26 |
2008-10-02 |
Trustees Of Tufts College |
Silk microspheres for encapsulation and controlled release
|
US8946200B2
(en)
*
|
2006-11-02 |
2015-02-03 |
Southwest Research Institute |
Pharmaceutically active nanosuspensions
|
AU2007234612B2
(en)
|
2006-12-14 |
2013-06-27 |
Johnson & Johnson Regenerative Therapeutics, Llc |
Protein stabilization formulations
|
WO2008076819A2
(en)
*
|
2006-12-18 |
2008-06-26 |
Altus Pharmaceuticals Inc. |
Human growth hormone formulations
|
US20100144599A1
(en)
*
|
2007-02-02 |
2010-06-10 |
Bristol-Myers Squibb Company |
Vegf pathway blockade
|
AU2008214359B2
(en)
|
2007-02-05 |
2014-01-16 |
Apellis Pharmaceuticals, Inc. |
Local complement inhibition for treatment of complement-mediated disorders
|
JP2010523564A
(ja)
*
|
2007-04-03 |
2010-07-15 |
トリメリス,インコーポレーテッド |
抗ウイルス性ペプチド治療薬の送達のための新規製剤
|
ES2402172T3
(es)
|
2007-04-23 |
2013-04-29 |
Intarcia Therapeutics, Inc |
Formulación en suspensión de péptidos insulinotrópicos y usos de los mismos
|
RU2472492C2
(ru)
*
|
2007-06-01 |
2013-01-20 |
Ново Нордиск А/С |
Стабильные неводные фармацевтические композиции
|
US7678764B2
(en)
|
2007-06-29 |
2010-03-16 |
Johnson & Johnson Regenerative Therapeutics, Llc |
Protein formulations for use at elevated temperatures
|
EP2187932B1
(en)
|
2007-08-07 |
2015-01-28 |
DePuy Synthes Products, LLC |
Protein formulations comprising gdf-5 in aqueous acidic solution
|
EP2201028A2
(en)
*
|
2007-09-25 |
2010-06-30 |
Trimeris, Inc. |
Novel methods of synthesis for therapeutic antiviral peptides
|
WO2009102467A2
(en)
|
2008-02-13 |
2009-08-20 |
Intarcia Therapeutics, Inc. |
Devices, formulations, and methods for delivery of multiple beneficial agents
|
US8404850B2
(en)
*
|
2008-03-13 |
2013-03-26 |
Southwest Research Institute |
Bis-quaternary pyridinium-aldoxime salts and treatment of exposure to cholinesterase inhibitors
|
PL2910570T3
(pl)
|
2008-03-18 |
2017-06-30 |
Novo Nordisk A/S |
Stabilizowane względem proteaz, acylowane analogi insuliny
|
CN102026619A
(zh)
*
|
2008-04-14 |
2011-04-20 |
先进科技及再生医学有限责任公司 |
液体缓冲的gdf-5制剂
|
US8722706B2
(en)
*
|
2008-08-15 |
2014-05-13 |
Southwest Research Institute |
Two phase bioactive formulations of bis-quaternary pyridinium oxime sulfonate salts
|
US8309134B2
(en)
*
|
2008-10-03 |
2012-11-13 |
Southwest Research Institute |
Modified calcium phosphate nanoparticle formation
|
UA106606C2
(uk)
*
|
2009-03-16 |
2014-09-25 |
Родія Оперейшнс |
Стабілізована біоцидна композиція
|
US20120070427A1
(en)
|
2009-06-01 |
2012-03-22 |
Trustees Of Tufts College |
Vortex-induced silk fibroin gelation for encapsulation and delivery
|
RU2431496C2
(ru)
*
|
2009-09-15 |
2011-10-20 |
Общество С Ограниченной Ответственностью "Герофарм" |
Инъекционная лекарственная форма для лечения острого ишемического инсульта и черепно-мозговой травмы, способ ее изготовления и применение
|
LT2462246T
(lt)
|
2009-09-28 |
2017-11-27 |
Intarcia Therapeutics, Inc |
Esminio stacionaraus vaisto tiekimo greitas įgyvendinimas ir (arba) nutraukimas
|
US9028873B2
(en)
*
|
2010-02-08 |
2015-05-12 |
Southwest Research Institute |
Nanoparticles for drug delivery to the central nervous system
|
WO2011109452A1
(en)
|
2010-03-01 |
2011-09-09 |
Bayer Healthcare Llc |
Optimized Monoclonal Antibodies against Tissue Factor Pathway Inhibitor (TFPI)
|
US9603971B2
(en)
|
2010-03-05 |
2017-03-28 |
Trustees Of Tufts College |
Silk-based ionomeric compositions
|
GB201004072D0
(en)
|
2010-03-11 |
2010-04-28 |
Turzi Antoine |
Process, tube and device for the preparation of wound healant composition
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
AU2012328739B2
(en)
|
2011-10-25 |
2017-11-30 |
Prothena Biosciences Limited |
Antibody formulations and methods
|
WO2013096835A1
(en)
*
|
2011-12-23 |
2013-06-27 |
Abbvie Inc. |
Stable protein formulations
|
WO2013112897A1
(en)
|
2012-01-27 |
2013-08-01 |
The Regents Of The University Of California |
Stabilization of biomolecules using sugar polymers
|
CA2870313A1
(en)
|
2012-04-11 |
2013-10-17 |
Novo Nordisk A/S |
Insulin formulations
|
WO2014035798A1
(en)
|
2012-08-30 |
2014-03-06 |
Sanofi |
Silk lyogels for sustained release of protein therapeutics and methods of making and uses
|
US8613919B1
(en)
|
2012-08-31 |
2013-12-24 |
Bayer Healthcare, Llc |
High concentration antibody and protein formulations
|
US9592297B2
(en)
|
2012-08-31 |
2017-03-14 |
Bayer Healthcare Llc |
Antibody and protein formulations
|
ES2887079T3
(es)
*
|
2014-04-28 |
2021-12-21 |
Eisai R&D Man Co Ltd |
Preparación de HGF liofilizada
|
US9889085B1
(en)
|
2014-09-30 |
2018-02-13 |
Intarcia Therapeutics, Inc. |
Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
|
AU2016270984B2
(en)
|
2015-06-03 |
2021-02-25 |
Intarcia Therapeutics, Inc. |
Implant placement and removal systems
|
JP2017110001A
(ja)
*
|
2015-12-16 |
2017-06-22 |
株式会社 資生堂 |
タブレット型凍結乾燥化粧料
|
RU2747977C2
(ru)
|
2016-03-17 |
2021-05-18 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Способ получения активного фактора роста гепатоцитов (hgf)
|
TWI814219B
(zh)
|
2016-05-16 |
2023-09-01 |
美商因塔希亞治療公司 |
升糖素受體選擇性多肽和彼之使用方法
|
USD860451S1
(en)
|
2016-06-02 |
2019-09-17 |
Intarcia Therapeutics, Inc. |
Implant removal tool
|
USD840030S1
(en)
|
2016-06-02 |
2019-02-05 |
Intarcia Therapeutics, Inc. |
Implant placement guide
|
EP3484450A4
(en)
*
|
2016-07-18 |
2020-04-01 |
Tissuegen, Inc. |
METHODS AND COMPOSITIONS FOR MAINTAINING THE CONFORMATION AND STRUCTURAL INTEGRITY OF BIOMOLECULES
|
RU2758367C2
(ru)
|
2016-12-16 |
2021-10-28 |
Ново Нордиск А/С |
Фармацевтические композиции, содержащие инсулин
|
IL267736B2
(en)
|
2017-01-03 |
2024-03-01 |
Intarcia Therapeutics Inc |
Methods involving continuous administration of a GLP-1 receptor agonist and co-administration of a drug
|
JP6404405B1
(ja)
*
|
2017-06-14 |
2018-10-10 |
株式会社 資生堂 |
タブレット型凍結乾燥化粧料
|
TWI787186B
(zh)
*
|
2017-06-19 |
2022-12-21 |
日商資生堂股份有限公司 |
錠型凍結乾燥化妝料
|
WO2018235147A1
(ja)
*
|
2017-06-19 |
2018-12-27 |
株式会社 資生堂 |
タブレット型凍結乾燥化粧料
|
CN108169499A
(zh)
*
|
2017-11-30 |
2018-06-15 |
成都斯马特科技有限公司 |
一种基于生化试剂盘进行凝血分析的方法
|
AU2019337671A1
(en)
*
|
2018-09-14 |
2021-05-13 |
Cara Therapeutics, Inc. |
Oral formulations of kappa opioid receptor agonists
|
CA3127191A1
(en)
|
2019-01-21 |
2020-07-30 |
Eclipse Medcorp, Llc |
Methods, systems and apparatus for separating components of a biological sample
|
BR112022008395A2
(pt)
|
2019-10-31 |
2022-08-23 |
Eclipse Medcorp Llc |
Sistemas, métodos e aparelhos para separar componentes de amostra
|
WO2023150580A2
(en)
*
|
2022-02-01 |
2023-08-10 |
Ocular Therapeutix, Inc. |
A controlled release implant for biologics and corresponding methods of treatment
|