DK1351703T3 - Anvendelse af et polypeptid omfattende det ekstracellulære domæne af IL-20RA og IL-20RB til behandling af inflammation - Google Patents
Anvendelse af et polypeptid omfattende det ekstracellulære domæne af IL-20RA og IL-20RB til behandling af inflammationInfo
- Publication number
- DK1351703T3 DK1351703T3 DK01970886T DK01970886T DK1351703T3 DK 1351703 T3 DK1351703 T3 DK 1351703T3 DK 01970886 T DK01970886 T DK 01970886T DK 01970886 T DK01970886 T DK 01970886T DK 1351703 T3 DK1351703 T3 DK 1351703T3
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptide
- inflammation
- treatment
- extracellular domain
- seq
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23330500P | 2000-09-15 | 2000-09-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1351703T3 true DK1351703T3 (da) | 2006-11-27 |
Family
ID=22876714
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01970886T DK1351703T3 (da) | 2000-09-15 | 2001-09-13 | Anvendelse af et polypeptid omfattende det ekstracellulære domæne af IL-20RA og IL-20RB til behandling af inflammation |
Country Status (10)
Country | Link |
---|---|
US (2) | US7855269B2 (da) |
EP (2) | EP1803733B1 (da) |
JP (1) | JP4908723B2 (da) |
AT (2) | ATE460429T1 (da) |
AU (1) | AU2001290837A1 (da) |
CA (1) | CA2422033A1 (da) |
DE (2) | DE60121808T2 (da) |
DK (1) | DK1351703T3 (da) |
ES (1) | ES2267814T3 (da) |
WO (1) | WO2002022153A2 (da) |
Families Citing this family (82)
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US5965704A (en) * | 1997-08-05 | 1999-10-12 | Zymogenetics, Inc. | Class two cytokine receptor-11 |
DE60123998T2 (de) * | 2000-08-08 | 2007-09-06 | Zymogenetics, Inc., Seattle | Lösliche zcyctor 11 cytokinrezeptoren |
EP1803733B1 (en) * | 2000-09-15 | 2010-03-10 | ZymoGenetics, Inc. | Polypeptides comprising the extracellular domains of IL-20RA and/or IL-20RB |
CA2519057A1 (en) * | 2003-03-24 | 2004-10-07 | Zymogenetics, Inc. | Anti-il-20 antibodies and binding partners and methods of using in inflammation |
US20040248097A1 (en) * | 2003-05-23 | 2004-12-09 | Ming-Shi Chang | Interleukin-20 variants and promoters |
EP2087905A2 (en) | 2003-08-08 | 2009-08-12 | Novo Nordisk A/S | Interleukin-20 for treating and diagnosing conditions associated with neovascularisation |
KR101520209B1 (ko) | 2003-11-06 | 2015-05-13 | 시애틀 지네틱스, 인크. | 리간드에 접합될 수 있는 모노메틸발린 화합물 |
WO2005052000A2 (en) * | 2003-11-21 | 2005-06-09 | Zymogenetics, Inc. | Anti-il-20 antibodies and binding partners and methods of using in inflammation |
MXPA06014065A (es) | 2004-06-01 | 2007-01-31 | Genentech Inc | Conjugados de droga-anticuerpo y metodos. |
US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
US7521541B2 (en) | 2004-09-23 | 2009-04-21 | Genetech Inc. | Cysteine engineered antibodies and conjugates |
WO2006047249A1 (en) | 2004-10-22 | 2006-05-04 | Zymogenetics, Inc. | Anti-il-22ra antibodies and binding partners and methods of using in inflammation |
AU2006212807A1 (en) * | 2005-02-08 | 2006-08-17 | Zymogenetics, Inc. | Anti-IL-20, anti-IL-22 and anti-IL-22RA antibodies and binding partners and methods of using in inflammation |
JP5368301B2 (ja) | 2006-06-22 | 2013-12-18 | ノボ・ノルデイスク・エー/エス | 可溶性ヘテロ二量体レセプター及びその使用 |
JP2013504585A (ja) | 2009-09-09 | 2013-02-07 | セントローズ, エルエルシー | 細胞外標的化薬物複合体 |
SI2528625T1 (sl) | 2010-04-15 | 2013-11-29 | Spirogen Sarl | Pirolobenzodiazepini in njihovi konjugati |
CN114246952A (zh) | 2010-06-08 | 2022-03-29 | 基因泰克公司 | 半胱氨酸改造的抗体和偶联物 |
CA2816426A1 (en) | 2010-11-17 | 2012-06-07 | Genentech, Inc. | Alaninyl maytansinol antibody conjugates |
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BR112014009050B1 (pt) | 2011-10-14 | 2022-06-21 | Medimmune Limited | Conjugado anticorpo-fármaco de pirrolbenzodiazepinas, composição farmacêutica que compreende o mesmo, bem como compostos de pirrolbenzodiazepinas |
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EP2906296B1 (en) | 2012-10-12 | 2018-03-21 | ADC Therapeutics SA | Pyrrolobenzodiazepine-antibody conjugates |
LT2906298T (lt) | 2012-10-12 | 2018-12-27 | Adc Therapeutics Sa | Pirolbenzodiazepino-antikūno konjugatai |
LT2906251T (lt) | 2012-10-12 | 2017-12-11 | Adc Therapeutics Sa | Pirolobenzodiazepino-anti-cd22 antikūno konjugatai |
EA029587B1 (ru) | 2012-10-12 | 2018-04-30 | Медимьюн Лимитед | Пирролбензодиазепины и их конъюгаты |
ES2690067T3 (es) | 2012-10-12 | 2018-11-19 | Adc Therapeutics Sa | Conjugados de anticuerpos anti-PSMA-Pirrolobenzodiazepinas |
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EA032986B1 (ru) | 2012-12-21 | 2019-08-30 | Медимьюн Лимитед | Пирролобензодиазепины |
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GB201317982D0 (en) | 2013-10-11 | 2013-11-27 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
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MX2016007578A (es) | 2013-12-16 | 2016-10-03 | Genentech Inc | Compuestos de conjugado anticuerpo-farmaco dimerico de 1-(clorometil)-2,3-dihidro-1h-benzo [e] indol, y metodos de uso y tratamiento. |
EP3149049B1 (en) | 2014-05-27 | 2022-10-26 | The University Of Queensland | Il-22 for use in treating metabolic disorders |
DK3151921T3 (da) | 2014-06-06 | 2019-12-02 | Bristol Myers Squibb Co | Antistoffer mod glucocorticoid-induceret tumornekrosefaktor- receptorer (gitr) og anvendelser deraf |
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CA2957354A1 (en) | 2014-09-12 | 2016-03-17 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
WO2016040825A1 (en) | 2014-09-12 | 2016-03-17 | Genentech, Inc. | Anthracycline disulfide intermediates, antibody-drug conjugates and methods |
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JP6878287B2 (ja) | 2014-11-25 | 2021-05-26 | アーデーセー セラピューティクス ソシエテ アノニム | ピロロベンゾジアゼピン−抗体コンジュゲート |
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GB201506402D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
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EP3304079B1 (en) | 2015-06-03 | 2020-06-03 | Bristol-Myers Squibb Company | Anti-gitr antibodies for cancer diagnostics |
MA43345A (fr) | 2015-10-02 | 2018-08-08 | Hoffmann La Roche | Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation |
MA43354A (fr) | 2015-10-16 | 2018-08-22 | Genentech Inc | Conjugués médicamenteux à pont disulfure encombré |
MA45326A (fr) | 2015-10-20 | 2018-08-29 | Genentech Inc | Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation |
WO2017087678A2 (en) | 2015-11-19 | 2017-05-26 | Bristol-Myers Squibb Company | Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof |
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JP6943872B2 (ja) | 2016-03-25 | 2021-10-06 | ジェネンテック, インコーポレイテッド | 多重全抗体及び抗体複合体化薬物定量化アッセイ |
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JP2019522633A (ja) | 2016-05-20 | 2019-08-15 | ジェネンテック, インコーポレイテッド | Protac抗体コンジュゲート及び使用方法 |
EP3465221B1 (en) | 2016-05-27 | 2020-07-22 | H. Hoffnabb-La Roche Ag | Bioanalytical method for the characterization of site-specific antibody-drug conjugates |
EP3464280B1 (en) | 2016-06-06 | 2021-10-06 | F. Hoffmann-La Roche AG | Silvestrol antibody-drug conjugates and methods of use |
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US20200129637A1 (en) | 2017-04-20 | 2020-04-30 | Adc Therapeutics Sa | Combination therapy with an anti-axl antibody-drug conjugate |
KR20200006115A (ko) | 2017-05-16 | 2020-01-17 | 브리스톨-마이어스 스큅 컴퍼니 | 항-gitr 효능제 항체에 의한 암의 치료 |
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US5567584A (en) * | 1988-01-22 | 1996-10-22 | Zymogenetics, Inc. | Methods of using biologically active dimerized polypeptide fusions to detect PDGF |
US5436155A (en) * | 1991-12-31 | 1995-07-25 | Arch Development Corporation | Isolated DNA encoding a somatostatin receptor |
US5789192A (en) | 1992-12-10 | 1998-08-04 | Schering Corporation | Mammalian receptors for interleukin-10 (IL-10) |
US5985614A (en) * | 1996-08-30 | 1999-11-16 | Human Genome Sciences, Inc. | Polynucleotides encoding interleukin-19 |
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WO2000012708A2 (en) | 1998-09-01 | 2000-03-09 | Genentech, Inc. | Further pro polypeptides and sequences thereof |
WO2000078961A1 (en) | 1999-06-23 | 2000-12-28 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WO1999003982A1 (en) | 1997-07-16 | 1999-01-28 | Human Genome Sciences, Inc. | Interleukin-20 |
US6486301B1 (en) * | 1997-07-16 | 2002-11-26 | Human Genome Sciences, Inc. | Interleukin-20 |
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EP1803733B1 (en) * | 2000-09-15 | 2010-03-10 | ZymoGenetics, Inc. | Polypeptides comprising the extracellular domains of IL-20RA and/or IL-20RB |
WO2002058724A2 (en) | 2001-01-26 | 2002-08-01 | Eli Lilly And Company | Use of lp82 to treat body weight disorders |
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-
2001
- 2001-09-13 EP EP05028379A patent/EP1803733B1/en not_active Expired - Lifetime
- 2001-09-13 WO PCT/US2001/028557 patent/WO2002022153A2/en active IP Right Grant
- 2001-09-13 EP EP01970886A patent/EP1351703B1/en not_active Expired - Lifetime
- 2001-09-13 CA CA002422033A patent/CA2422033A1/en not_active Abandoned
- 2001-09-13 DE DE60121808T patent/DE60121808T2/de not_active Expired - Lifetime
- 2001-09-13 US US09/951,268 patent/US7855269B2/en not_active Expired - Fee Related
- 2001-09-13 AT AT05028379T patent/ATE460429T1/de not_active IP Right Cessation
- 2001-09-13 DK DK01970886T patent/DK1351703T3/da active
- 2001-09-13 AU AU2001290837A patent/AU2001290837A1/en not_active Abandoned
- 2001-09-13 ES ES01970886T patent/ES2267814T3/es not_active Expired - Lifetime
- 2001-09-13 DE DE60141546T patent/DE60141546D1/de not_active Expired - Lifetime
- 2001-09-13 AT AT01970886T patent/ATE333888T1/de active
- 2001-09-13 JP JP2002526403A patent/JP4908723B2/ja not_active Expired - Fee Related
-
2010
- 2010-11-09 US US12/942,302 patent/US20110077207A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2002022153A3 (en) | 2003-06-19 |
WO2002022153A2 (en) | 2002-03-21 |
DE60121808T2 (de) | 2007-03-29 |
EP1351703A2 (en) | 2003-10-15 |
EP1803733A3 (en) | 2007-10-31 |
US20110077207A1 (en) | 2011-03-31 |
US7855269B2 (en) | 2010-12-21 |
AU2001290837A1 (en) | 2002-03-26 |
EP1803733A2 (en) | 2007-07-04 |
ES2267814T3 (es) | 2007-03-16 |
US20020085992A1 (en) | 2002-07-04 |
EP1351703B1 (en) | 2006-07-26 |
ATE460429T1 (de) | 2010-03-15 |
DE60141546D1 (de) | 2010-04-22 |
EP1803733B1 (en) | 2010-03-10 |
JP2004525074A (ja) | 2004-08-19 |
ATE333888T1 (de) | 2006-08-15 |
CA2422033A1 (en) | 2002-03-21 |
DE60121808D1 (de) | 2006-09-07 |
JP4908723B2 (ja) | 2012-04-04 |
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