DE60141546D1 - Polypeptide enthaltend extrazellulären Domäne von IL-20RA und/oderr IL-20RB - Google Patents
Polypeptide enthaltend extrazellulären Domäne von IL-20RA und/oderr IL-20RBInfo
- Publication number
- DE60141546D1 DE60141546D1 DE60141546T DE60141546T DE60141546D1 DE 60141546 D1 DE60141546 D1 DE 60141546D1 DE 60141546 T DE60141546 T DE 60141546T DE 60141546 T DE60141546 T DE 60141546T DE 60141546 D1 DE60141546 D1 DE 60141546D1
- Authority
- DE
- Germany
- Prior art keywords
- extracellular domain
- polypeptides containing
- seq
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23330500P | 2000-09-15 | 2000-09-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60141546D1 true DE60141546D1 (de) | 2010-04-22 |
Family
ID=22876714
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60121808T Expired - Lifetime DE60121808T2 (de) | 2000-09-15 | 2001-09-13 | Verwendung eines polypeptids, welches die extrazelluläre domäne von il-20ra und il-20rb enthält, zur behandlung von entzündungen |
DE60141546T Expired - Lifetime DE60141546D1 (de) | 2000-09-15 | 2001-09-13 | Polypeptide enthaltend extrazellulären Domäne von IL-20RA und/oderr IL-20RB |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60121808T Expired - Lifetime DE60121808T2 (de) | 2000-09-15 | 2001-09-13 | Verwendung eines polypeptids, welches die extrazelluläre domäne von il-20ra und il-20rb enthält, zur behandlung von entzündungen |
Country Status (10)
Country | Link |
---|---|
US (2) | US7855269B2 (de) |
EP (2) | EP1351703B1 (de) |
JP (1) | JP4908723B2 (de) |
AT (2) | ATE333888T1 (de) |
AU (1) | AU2001290837A1 (de) |
CA (1) | CA2422033A1 (de) |
DE (2) | DE60121808T2 (de) |
DK (1) | DK1351703T3 (de) |
ES (1) | ES2267814T3 (de) |
WO (1) | WO2002022153A2 (de) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5965704A (en) * | 1997-08-05 | 1999-10-12 | Zymogenetics, Inc. | Class two cytokine receptor-11 |
JP5015404B2 (ja) * | 2000-08-08 | 2012-08-29 | ザイモジェネティクス, インコーポレイテッド | 可溶性zcytor11サイトカイン受容体 |
ATE333888T1 (de) * | 2000-09-15 | 2006-08-15 | Zymogenetics Inc | Verwendung eines polypeptids, welches die extrazelluläre domäne von il-20ra und il-20rb enthält, zur behandlung von entzündungen |
CN103864934A (zh) * | 2003-03-24 | 2014-06-18 | 津莫吉尼蒂克斯公司 | 抗il-22ra抗体和结合伴侣以及在炎症中的使用方法 |
US20040248097A1 (en) * | 2003-05-23 | 2004-12-09 | Ming-Shi Chang | Interleukin-20 variants and promoters |
EP1653995A1 (de) * | 2003-08-08 | 2006-05-10 | Novo Nordisk A/S | Interleukin-20 zur behandlung und diagnose von mit neovaskularization verbunden zuständen |
KR101192496B1 (ko) | 2003-11-06 | 2012-10-18 | 시애틀 지네틱스, 인크. | 리간드에 접합될 수 있는 모노메틸발린 화합물 |
WO2005052001A2 (en) * | 2003-11-21 | 2005-06-09 | Zymogenetics, Inc. | Anti-il-20 receptor antibodies and binding partners and methods of using in inflammation |
CN114053429A (zh) | 2004-06-01 | 2022-02-18 | 健泰科生物技术公司 | 抗体-药物偶联物和方法 |
RU2412947C2 (ru) | 2004-09-23 | 2011-02-27 | Дженентек, Инк. | Антитела, сконструированные на основе цистеинов, и их конъюгаты |
US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
DE602005022475D1 (de) | 2004-10-22 | 2010-09-02 | Zymogenetics Inc | Anti-il-22ra-antikörper und bindungspartner und verfahren zur anwendung bei entzündungen |
WO2006086396A2 (en) * | 2005-02-08 | 2006-08-17 | Zymogenetics, Inc. | Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation |
EP2035452B1 (de) | 2006-06-22 | 2012-04-25 | Novo Nordisk A/S | Lösliche heterodimere rezeptoren und ihre verwendung |
JP2013504585A (ja) | 2009-09-09 | 2013-02-07 | セントローズ, エルエルシー | 細胞外標的化薬物複合体 |
PE20130342A1 (es) | 2010-04-15 | 2013-04-20 | Spirogen Sarl | Pirrolobenzodiacepinas y conjugados de las mismas |
WO2011156328A1 (en) | 2010-06-08 | 2011-12-15 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
CA2816426A1 (en) | 2010-11-17 | 2012-06-07 | Genentech, Inc. | Alaninyl maytansinol antibody conjugates |
CA2833212C (en) | 2011-05-12 | 2020-06-09 | Genentech, Inc. | Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature peptides |
KR101877598B1 (ko) | 2011-10-14 | 2018-07-11 | 메디뮨 리미티드 | 피롤로벤조디아제핀 및 그의 컨주게이트 |
WO2013130093A1 (en) | 2012-03-02 | 2013-09-06 | Genentech, Inc. | Biomarkers for treatment with anti-tubulin chemotherapeutic compounds |
ES2680153T3 (es) | 2012-10-12 | 2018-09-04 | Adc Therapeutics Sa | Conjugados de anticuerpos anti-PSMA-pirrolobenzodiazepinas |
EP2906297B1 (de) | 2012-10-12 | 2017-12-06 | ADC Therapeutics SA | Pyrrolobenzodiazepin-antikörper-konjugate |
ES2670937T3 (es) | 2012-10-12 | 2018-06-04 | Medimmune Limited | Conjugados de anticuerpo-pirrolobenzodiazepina |
CA2941485C (en) | 2012-10-12 | 2018-06-12 | Philip Wilson Howard | Pyrrolobenzodiazepines and conjugates thereof |
JP6392763B2 (ja) | 2012-10-12 | 2018-09-19 | エイディーシー・セラピューティクス・エス・アーAdc Therapeutics Sa | ピロロベンゾジアゼピン−抗体結合体 |
RS56520B1 (sr) | 2012-10-12 | 2018-02-28 | Adc Therapeutics Sa | Pirolobenzodiazepin-anti-cd22 konjugati antitela |
US10751346B2 (en) | 2012-10-12 | 2020-08-25 | Medimmune Limited | Pyrrolobenzodiazepine—anti-PSMA antibody conjugates |
AU2013366490B9 (en) | 2012-12-21 | 2018-02-01 | Medimmune Limited | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
EP2935268B2 (de) | 2012-12-21 | 2021-02-17 | MedImmune Limited | Pyrrolobenzodiazepine und konjugate davon |
BR112015023070B1 (pt) | 2013-03-13 | 2022-06-07 | Genentech, Inc. | Conjugados e compostos de pirrolobenzodiazepinas, composição farmacêutica que compreende os mesmo, bem como seus usos para o tratamento de uma doença proliferativa |
JP6340019B2 (ja) | 2013-03-13 | 2018-06-06 | メドイミューン・リミテッドMedImmune Limited | ピロロベンゾジアゼピン及びそのコンジュゲート |
BR112015023333A8 (pt) | 2013-03-13 | 2018-04-17 | Medimmune Ltd | pirrolbenzodiazepinas e conjugados dos mesmos |
WO2015023355A1 (en) | 2013-08-12 | 2015-02-19 | Genentech, Inc. | 1-(chloromethyl)-2,3-dihydro-1h-benzo[e]indole dimer antibody-drug conjugate compounds, and methods of use and treatment |
GB201317982D0 (en) | 2013-10-11 | 2013-11-27 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
EP3054986B1 (de) | 2013-10-11 | 2019-03-20 | Medimmune Limited | Pyrrolobenzodiazepin-antikörper-konjugate |
EP3054983B1 (de) | 2013-10-11 | 2019-03-20 | Medimmune Limited | Pyrrolobenzodiazepin-antikörper-konjugate |
EP3054985B1 (de) | 2013-10-11 | 2018-12-26 | Medimmune Limited | Pyrrolobenzodiazepin-antikörper-konjugate |
AU2014364927A1 (en) | 2013-12-16 | 2016-07-07 | Genentech, Inc. | Peptidomimetic compounds and antibody-drug conjugates thereof |
RU2689388C1 (ru) | 2013-12-16 | 2019-05-28 | Дженентек, Инк. | Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами |
JP6980384B2 (ja) | 2013-12-16 | 2021-12-15 | ジェネンテック, インコーポレイテッド | 1−(クロロメチル)−2,3−ジヒドロ−1h−ベンゾ[e]インドール二量体抗体−薬物コンジュゲート化合物、並びに使用及び処置の方法 |
WO2015179918A1 (en) | 2014-05-27 | 2015-12-03 | The University Of Queensland | Modulation of cellular stress |
EA037006B1 (ru) | 2014-06-06 | 2021-01-26 | Бристол-Майерс Сквибб Компани | Антитела к индуцируемому глюкокортикоидами рецептору фактора некроза опухолей (gitr) и их применения |
US10188746B2 (en) | 2014-09-10 | 2019-01-29 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
EP3191134B1 (de) | 2014-09-12 | 2019-11-20 | Genentech, Inc. | Anthracyclindisulfidzwischenprodukte, antikörper-wirkstoff-konjugate und verfahren |
RU2017107502A (ru) | 2014-09-12 | 2018-10-12 | Дженентек, Инк. | Антитела и конъюгаты, сконструированные введением цистеина |
GB201416112D0 (en) | 2014-09-12 | 2014-10-29 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
KR20170067771A (ko) | 2014-09-17 | 2017-06-16 | 제넨테크, 인크. | 피롤로벤조디아제핀 및 이의 항체 디설파이드 컨주게이트 |
EP3223854A1 (de) | 2014-11-25 | 2017-10-04 | ADC Therapeutics SA | Pyrrolobenzodiazepin-antikörper-konjugate |
KR20170086121A (ko) | 2014-12-03 | 2017-07-25 | 제넨테크, 인크. | 4급 아민 화합물 및 그의 항체-약물 접합체 |
GB201506402D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
JP6812364B2 (ja) | 2015-06-03 | 2021-01-13 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 癌診断用抗gitr抗体 |
MA43345A (fr) | 2015-10-02 | 2018-08-08 | Hoffmann La Roche | Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation |
MA43354A (fr) | 2015-10-16 | 2018-08-22 | Genentech Inc | Conjugués médicamenteux à pont disulfure encombré |
MA45326A (fr) | 2015-10-20 | 2018-08-29 | Genentech Inc | Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation |
EA201891121A1 (ru) | 2015-11-19 | 2018-12-28 | Бристол-Майерс Сквибб Компани | Антитела к глюкокортикоид-индуцированному рецептору фактора некроза опухоли (gitr) и их применения |
GB201601431D0 (en) | 2016-01-26 | 2016-03-09 | Medimmune Ltd | Pyrrolobenzodiazepines |
GB201602356D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
GB201602359D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
CN108700598A (zh) | 2016-03-25 | 2018-10-23 | 豪夫迈·罗氏有限公司 | 多路总抗体和抗体缀合的药物量化测定法 |
GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
WO2017201449A1 (en) | 2016-05-20 | 2017-11-23 | Genentech, Inc. | Protac antibody conjugates and methods of use |
WO2017205741A1 (en) | 2016-05-27 | 2017-11-30 | Genentech, Inc. | Bioanalytical method for the characterization of site-specific antibody-drug conjugates |
EP3464280B1 (de) | 2016-06-06 | 2021-10-06 | F. Hoffmann-La Roche AG | Silvestrol-antikörper-arzneimittelkonjugate und verfahren zur verwendung |
EP3496763A1 (de) | 2016-08-11 | 2019-06-19 | Genentech, Inc. | Pyrrolobenzodiazepin-prodrugs und antikörperkonjugate davon |
CN110139674B (zh) | 2016-10-05 | 2023-05-16 | 豪夫迈·罗氏有限公司 | 制备抗体药物缀合物的方法 |
GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
GB201702031D0 (en) | 2017-02-08 | 2017-03-22 | Medlmmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
MX2019009428A (es) | 2017-02-08 | 2019-10-07 | Adc Therapeutics Sa | Conjugados de pirrolobenzodiazepinas y anticuerpos. |
HUE059828T2 (hu) | 2017-04-18 | 2023-01-28 | Medimmune Ltd | Pirrolobenzodiazepin konjugátumok |
JP7408396B2 (ja) | 2017-04-20 | 2024-01-05 | アーデーセー セラピューティクス ソシエテ アノニム | 併用療法 |
US11685787B2 (en) | 2017-05-16 | 2023-06-27 | Bristol-Myers Squibb Company | Treatment of cancer with anti-GITR agonist antibodies |
BR112019026564A2 (pt) | 2017-06-14 | 2020-06-30 | Adc Therapeutics Sa | regimes de dosagem para a administração de um adc anti-cd19 |
LT3668874T (lt) | 2017-08-18 | 2022-03-25 | Medimmune Limited | Pirolobenzodiazepino konjugatai |
IL302943A (en) | 2017-09-20 | 2023-07-01 | Ph Pharma Co Ltd | Thylanstatin analogs |
GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
GB201814281D0 (en) | 2018-09-03 | 2018-10-17 | Femtogenix Ltd | Cytotoxic agents |
EP3870235A1 (de) | 2018-10-24 | 2021-09-01 | F. Hoffmann-La Roche AG | Konjugierte chemische abbauauslöser und verwendungsverfahren |
EP3894427A1 (de) | 2018-12-10 | 2021-10-20 | Genentech, Inc. | Photovernetzende peptide zur stellenspezifischen konjugation an fc-haltige proteine |
GB201901197D0 (en) | 2019-01-29 | 2019-03-20 | Femtogenix Ltd | G-A Crosslinking cytotoxic agents |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5567584A (en) * | 1988-01-22 | 1996-10-22 | Zymogenetics, Inc. | Methods of using biologically active dimerized polypeptide fusions to detect PDGF |
US5436155A (en) * | 1991-12-31 | 1995-07-25 | Arch Development Corporation | Isolated DNA encoding a somatostatin receptor |
US5789192A (en) | 1992-12-10 | 1998-08-04 | Schering Corporation | Mammalian receptors for interleukin-10 (IL-10) |
US5985614A (en) * | 1996-08-30 | 1999-11-16 | Human Genome Sciences, Inc. | Polynucleotides encoding interleukin-19 |
US5945511A (en) * | 1997-02-20 | 1999-08-31 | Zymogenetics, Inc. | Class II cytokine receptor |
WO2000078961A1 (en) | 1999-06-23 | 2000-12-28 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US6486301B1 (en) * | 1997-07-16 | 2002-11-26 | Human Genome Sciences, Inc. | Interleukin-20 |
AU8571198A (en) | 1997-07-16 | 1999-02-10 | Human Genome Sciences, Inc. | Interleukin-20 |
US5965704A (en) | 1997-08-05 | 1999-10-12 | Zymogenetics, Inc. | Class two cytokine receptor-11 |
AU8899298A (en) * | 1997-08-06 | 1999-03-01 | Zymogenetics Inc. | Lipocalin homologs |
US6576743B1 (en) * | 1997-11-26 | 2003-06-10 | Zymogenetics, Inc. | Mammalian cytokine-like polypeptide-10 |
CA2312000C (en) | 1997-11-26 | 2013-03-26 | Zymogenetics, Inc. | Mammalian cytokine-like polypeptide-10 |
DK1047781T3 (da) | 1998-01-23 | 2004-12-06 | Immunex Corp | IL-18-receptorer |
CA2323236A1 (en) | 1998-03-09 | 1999-09-16 | Schering Corporation | Human receptor proteins; related reagents and methods |
DK1490386T3 (da) | 1998-03-10 | 2008-12-15 | Genentech Inc | Nyt polypeptid og nukleinsyrer kodende for dette |
US6982320B2 (en) | 1998-03-19 | 2006-01-03 | Human Genome Sciences, Inc. | Cytokine receptor common gamma chain like |
AU5203199A (en) | 1998-05-26 | 1999-12-13 | Procter & Gamble Company, The | Chimeric molecules comprising an extracellular ligand binding domain of a receptor and an ige fc or constant region, and their use in an assay system |
NZ531664A (en) | 1998-09-01 | 2005-07-29 | Genentech Inc | Pro1317 polypeptides and sequences thereof with homology to the semaphorin B glycoprotein family |
AU2222700A (en) | 1998-12-31 | 2000-07-31 | Millennium Pharmaceuticals, Inc. | Class ii cytokine receptor-like proteins and nucleic acids encoding them |
AU5047600A (en) | 1999-05-27 | 2000-12-18 | Schering Corporation | Mammalian interleukin-10 homologs: il-d110 and il-d210 |
US7122632B2 (en) * | 1999-12-23 | 2006-10-17 | Zymogenetics, Inc. | Soluble Interleukin-20 receptor |
EP1857466B1 (de) | 1999-12-23 | 2010-10-20 | ZymoGenetics, Inc. | Löslicher Interleukin-20-Rezeptor |
JP2003535037A (ja) * | 1999-12-23 | 2003-11-25 | ザイモジェネティクス,インコーポレイティド | 炎症を治療する方法 |
US6610286B2 (en) * | 1999-12-23 | 2003-08-26 | Zymogenetics, Inc. | Method for treating inflammation using soluble receptors to interleukin-20 |
JP5015404B2 (ja) | 2000-08-08 | 2012-08-29 | ザイモジェネティクス, インコーポレイテッド | 可溶性zcytor11サイトカイン受容体 |
ATE333888T1 (de) * | 2000-09-15 | 2006-08-15 | Zymogenetics Inc | Verwendung eines polypeptids, welches die extrazelluläre domäne von il-20ra und il-20rb enthält, zur behandlung von entzündungen |
EP1390060A2 (de) | 2001-01-26 | 2004-02-25 | Eli Lilly And Company | Verwendung von lp82 zur behandlung von störungen des körpergewichtes |
JP2005506287A (ja) | 2001-02-28 | 2005-03-03 | イーライ・リリー・アンド・カンパニー | 造血障害を治療するためのlp82の使用 |
DK1399472T3 (da) | 2001-03-09 | 2009-10-05 | Zymogenetics Inc | Oplöselig heterodimer cytokinreceptor |
DE10154579A1 (de) | 2001-11-07 | 2003-05-28 | Medigene Ag | Topikale Verwendung von Cytokinen und Chemokinen zur Behandlung von viralen oder mykotischen Hauterkrankungen oder Tumorerkrankungen |
PT1531843E (pt) | 2001-12-17 | 2011-10-27 | Zymogenetics Inc | Método para tratar o cancro cervical |
CN103864934A (zh) | 2003-03-24 | 2014-06-18 | 津莫吉尼蒂克斯公司 | 抗il-22ra抗体和结合伴侣以及在炎症中的使用方法 |
-
2001
- 2001-09-13 AT AT01970886T patent/ATE333888T1/de active
- 2001-09-13 US US09/951,268 patent/US7855269B2/en not_active Expired - Fee Related
- 2001-09-13 AT AT05028379T patent/ATE460429T1/de not_active IP Right Cessation
- 2001-09-13 WO PCT/US2001/028557 patent/WO2002022153A2/en active IP Right Grant
- 2001-09-13 CA CA002422033A patent/CA2422033A1/en not_active Abandoned
- 2001-09-13 DE DE60121808T patent/DE60121808T2/de not_active Expired - Lifetime
- 2001-09-13 DE DE60141546T patent/DE60141546D1/de not_active Expired - Lifetime
- 2001-09-13 EP EP01970886A patent/EP1351703B1/de not_active Expired - Lifetime
- 2001-09-13 ES ES01970886T patent/ES2267814T3/es not_active Expired - Lifetime
- 2001-09-13 AU AU2001290837A patent/AU2001290837A1/en not_active Abandoned
- 2001-09-13 DK DK01970886T patent/DK1351703T3/da active
- 2001-09-13 EP EP05028379A patent/EP1803733B1/de not_active Expired - Lifetime
- 2001-09-13 JP JP2002526403A patent/JP4908723B2/ja not_active Expired - Fee Related
-
2010
- 2010-11-09 US US12/942,302 patent/US20110077207A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE460429T1 (de) | 2010-03-15 |
US20110077207A1 (en) | 2011-03-31 |
EP1803733A3 (de) | 2007-10-31 |
JP2004525074A (ja) | 2004-08-19 |
US7855269B2 (en) | 2010-12-21 |
AU2001290837A1 (en) | 2002-03-26 |
WO2002022153A2 (en) | 2002-03-21 |
ES2267814T3 (es) | 2007-03-16 |
ATE333888T1 (de) | 2006-08-15 |
JP4908723B2 (ja) | 2012-04-04 |
DK1351703T3 (da) | 2006-11-27 |
DE60121808D1 (de) | 2006-09-07 |
CA2422033A1 (en) | 2002-03-21 |
DE60121808T2 (de) | 2007-03-29 |
EP1351703A2 (de) | 2003-10-15 |
EP1803733A2 (de) | 2007-07-04 |
US20020085992A1 (en) | 2002-07-04 |
EP1803733B1 (de) | 2010-03-10 |
WO2002022153A3 (en) | 2003-06-19 |
EP1351703B1 (de) | 2006-07-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE460429T1 (de) | Polypeptide enthaltend extrazellulären domäne von il-20ra und/oderr il-20rb | |
ATE462006T1 (de) | Isoform des vegfs | |
BR0012759A (pt) | Neurotoxinas recombinantes ativáveis | |
ATE419273T1 (de) | Translokationsvektoren abgeleitet von der antennapedia homeodomain helix 3 | |
DK0397633T3 (da) | Fibronectinbindende protein samt fremstilling deraf | |
DE69838143D1 (de) | Antimikrobielle peptide | |
HUP0100094A1 (hu) | Új felületi antigén | |
PT1346034E (pt) | Polipéptido da protease de clivagem do factor de von willebrand (vwf), ácido nucleico que codifica o polipéptido e utilização do polipéptido | |
DK0960127T3 (da) | Isoleret dimert fibroblastaktiverende protein-alfa og anvendelser deraf | |
ATE394484T1 (de) | Smad 6 und dessen anwendungen | |
ATE368688T1 (de) | Peptide, deren herstellung und verwendung zur bindung von immunglobulinen | |
DK1908772T3 (da) | Polypeptider og polynucleinsyrer af phorphorymonas gingivalis | |
ATE417618T1 (de) | Faktor-viii-polypeptide auf hohem expressionsniveau codierende nukleinsäure- und aminosäuresequenzen und verwendungsverfahren | |
DE69715181D1 (de) | Peptid der löslichen form von acetylcholinesterase mit aktivität als calciumkanalmodulator | |
NO922421D0 (no) | Collagenbindende protein, samt fremstilling derav | |
DE69938130D1 (de) | Neue peptide | |
PT773999E (pt) | Receptor orfao or-1 pertencente a familia de receptores nucleares | |
DK0942992T3 (da) | O-fucosyltransferase | |
DE60329115D1 (de) | Tumorantigenprotein und dessen verwendung | |
ATE344802T1 (de) | Angiogenese-assoziierte proteine und dafür kodierende nukleinsäure | |
DE69518927D1 (de) | Ein mit katp-kanälen wechselwirkendes protein | |
ATE393224T1 (de) | Nukleinsäuresequenzen von hyperplasien und tumoren der schilddrüse | |
WO2002031127A3 (en) | Cloning and recombinant expression of mammalian group xii secreted phospholipase a¿2? | |
GB2361923A (en) | Novel protein | |
DE60021707D1 (de) | Beta-primeverosidase gen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |