DK1025859T3 - Pulverformige pernasale præparater - Google Patents
Pulverformige pernasale præparaterInfo
- Publication number
- DK1025859T3 DK1025859T3 DK99938613T DK99938613T DK1025859T3 DK 1025859 T3 DK1025859 T3 DK 1025859T3 DK 99938613 T DK99938613 T DK 99938613T DK 99938613 T DK99938613 T DK 99938613T DK 1025859 T3 DK1025859 T3 DK 1025859T3
- Authority
- DK
- Denmark
- Prior art keywords
- pernasal
- powdered
- preparations
- drug
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Otolaryngology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP24024298 | 1998-08-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1025859T3 true DK1025859T3 (da) | 2006-10-16 |
Family
ID=17056580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99938613T DK1025859T3 (da) | 1998-08-26 | 1999-08-24 | Pulverformige pernasale præparater |
Country Status (15)
Country | Link |
---|---|
US (1) | US6428805B1 (da) |
EP (1) | EP1025859B1 (da) |
JP (1) | JP4338313B2 (da) |
KR (1) | KR100611025B1 (da) |
CN (1) | CN1160127C (da) |
AT (1) | ATE331532T1 (da) |
AU (1) | AU762145C (da) |
CA (1) | CA2307607C (da) |
DE (1) | DE69932144T8 (da) |
DK (1) | DK1025859T3 (da) |
ES (1) | ES2263282T3 (da) |
HK (1) | HK1030145A1 (da) |
PT (1) | PT1025859E (da) |
TW (1) | TW553746B (da) |
WO (1) | WO2000012136A1 (da) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69924504T2 (de) | 1998-08-26 | 2006-02-16 | Teijin Ltd. | Pulverförmige pernasale mittel |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
MXPA03005980A (es) | 2001-07-05 | 2003-09-10 | Translational Res Ltd | Composiciones para administracion nasal de insulina. |
ATE385193T1 (de) | 2002-03-20 | 2008-02-15 | Mannkind Corp | Inhalationsgerät |
US20080260838A1 (en) * | 2003-08-01 | 2008-10-23 | Mannkind Corporation | Glucagon-like peptide 1 (glp-1) pharmaceutical formulations |
WO2004073729A1 (ja) | 2003-02-21 | 2004-09-02 | Translational Research Ltd. | 薬物の経鼻投与用組成物 |
KR100974482B1 (ko) | 2003-03-27 | 2010-08-10 | 가부시키가이샤 바이오악티스 | 비강용 분말 약제 투약 장치 |
US6986944B2 (en) * | 2003-05-20 | 2006-01-17 | Eastman Kodak Company | Core-shell nitro-resin particles and method of preparation |
WO2006016530A1 (ja) * | 2004-08-10 | 2006-02-16 | Translational Research, Ltd. | 速効性でかつ高い吸収性を可能とする経鼻投与用組成物 |
CN101010305B (zh) | 2004-08-20 | 2010-08-11 | 曼金德公司 | 二酮哌嗪合成的催化反应 |
DK1791542T3 (da) | 2004-08-23 | 2015-06-15 | Mannkind Corp | Diketopiperazinsalte til lægemiddel-levering |
US7115561B2 (en) * | 2004-09-22 | 2006-10-03 | Patterson James A | Medicament composition and method of administration |
JP2009504767A (ja) * | 2005-08-17 | 2009-02-05 | フレミング・アンド・カンパニー・ファーマシューティカルズ | ビタミンb12鼻用スプレーおよび使用方法 |
MX358592B (es) | 2005-09-14 | 2018-08-27 | Mannkind Corp | Método para formulación de fármaco basado en el aumento de la afinidad de superficies de micropartículas cristalinas hacia agentes activos. |
RU2403059C2 (ru) | 2006-02-22 | 2010-11-10 | Маннкайнд Корпорейшн | Способ улучшения фармацевтических свойств микрочастиц, содержащих дикетопиперазин и активный агент |
WO2008078730A1 (ja) | 2006-12-26 | 2008-07-03 | Translational Research, Ltd. | 経鼻投与用製剤 |
WO2008091588A1 (en) | 2007-01-22 | 2008-07-31 | Targacept, Inc. | Intranasal, buccal, and sublingual administration of metanicotine analogs |
ES2547529T3 (es) * | 2007-10-24 | 2015-10-07 | Mannkind Corporation | Formulación en polvo seco inhalable que comprende GLP-1 para usar en el tratamiento de la hiperglucemia y diabetes por administración pulmonar |
EP2253326B1 (en) | 2008-02-28 | 2018-04-04 | Toray Industries, Inc. | Pharmaceutical composition for transnasal administration |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
KR101548092B1 (ko) | 2008-06-13 | 2015-08-27 | 맨카인드 코포레이션 | 건조 분말 흡입기 및 약물 투여 시스템 |
ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
EP2676695A3 (en) | 2009-03-11 | 2017-03-01 | MannKind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
JP2012526726A (ja) | 2009-05-15 | 2012-11-01 | 株式会社新日本科学 | 薬物動態が改善された鼻腔内用薬学的組成物 |
WO2010144789A2 (en) | 2009-06-12 | 2010-12-16 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
GB2472327B (en) | 2009-07-31 | 2013-03-13 | Shin Nippon Biomedical Lab Ltd | Intranasal granisetron and nasal applicator |
JP5784622B2 (ja) | 2009-11-03 | 2015-09-24 | マンカインド コーポレ−ション | 吸入活動をシミュレートするための装置及び方法 |
CN102985125A (zh) | 2010-06-21 | 2013-03-20 | 曼金德公司 | 干粉药物输送系统和方法 |
JP6133270B2 (ja) | 2011-04-01 | 2017-05-24 | マンカインド コーポレイション | 薬剤カートリッジのためのブリスター包装 |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
JP6018640B2 (ja) | 2011-10-24 | 2016-11-02 | マンカインド コーポレイション | 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム |
RU2650035C2 (ru) | 2012-07-12 | 2018-04-06 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
MX2020009878A (es) | 2013-07-18 | 2022-07-27 | Mannkind Corp | Composiciones farmaceuticas en polvo seco estables al calor y metodos. |
EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
WO2019103108A1 (ja) | 2017-11-27 | 2019-05-31 | あすか製薬株式会社 | 粉末経鼻投与製剤 |
EP4232006A4 (en) * | 2020-12-16 | 2024-05-08 | Liw Innovation Ab | NEW POWDER COMPOSITION |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1577196A (en) * | 1977-06-03 | 1980-10-22 | Ile De France | Compositions containing erythromycin and metoclopramide |
JPS59163313A (ja) * | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
GB2193891B (en) * | 1986-08-18 | 1990-07-25 | Sandoz Ltd | Nasal pharmaceutical composition containing a somatostatin anologue. |
GB9020544D0 (en) * | 1990-09-20 | 1990-10-31 | Sandoz Ltd | Improvements in or relating to organic compounds |
WO1995003818A1 (fr) * | 1993-07-30 | 1995-02-09 | Teijin Limited | Poudre permettant l'administration par voie nasale d'un medicament peptidique ou proteique |
JPH07242550A (ja) * | 1994-03-02 | 1995-09-19 | Teijin Ltd | 二次性副甲状腺機能亢進症治療剤 |
PT943326E (pt) * | 1996-02-27 | 2003-12-31 | Teijin Ltd | Composicao em po para administracao nasal |
TW503113B (en) * | 1997-01-16 | 2002-09-21 | Senju Pharma Co | Aqueous suspension for nasal administration |
JP3386349B2 (ja) | 1997-10-30 | 2003-03-17 | 帝人株式会社 | 水性懸濁医薬品組成物 |
-
1999
- 1999-08-24 CA CA002307607A patent/CA2307607C/en not_active Expired - Fee Related
- 1999-08-24 WO PCT/JP1999/004560 patent/WO2000012136A1/ja active IP Right Grant
- 1999-08-24 AT AT99938613T patent/ATE331532T1/de active
- 1999-08-24 DK DK99938613T patent/DK1025859T3/da active
- 1999-08-24 AU AU53059/99A patent/AU762145C/en not_active Ceased
- 1999-08-24 EP EP99938613A patent/EP1025859B1/en not_active Expired - Lifetime
- 1999-08-24 CN CNB998019119A patent/CN1160127C/zh not_active Expired - Fee Related
- 1999-08-24 PT PT99938613T patent/PT1025859E/pt unknown
- 1999-08-24 KR KR1020007004462A patent/KR100611025B1/ko not_active IP Right Cessation
- 1999-08-24 US US09/530,203 patent/US6428805B1/en not_active Expired - Lifetime
- 1999-08-24 DE DE69932144T patent/DE69932144T8/de active Active
- 1999-08-24 JP JP2000567246A patent/JP4338313B2/ja not_active Expired - Fee Related
- 1999-08-24 ES ES99938613T patent/ES2263282T3/es not_active Expired - Lifetime
- 1999-08-26 TW TW088114652A patent/TW553746B/zh not_active IP Right Cessation
-
2001
- 2001-02-08 HK HK01100899A patent/HK1030145A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU5305999A (en) | 2000-03-21 |
HK1030145A1 (en) | 2001-04-27 |
AU762145B2 (en) | 2003-06-19 |
TW553746B (en) | 2003-09-21 |
CN1287495A (zh) | 2001-03-14 |
EP1025859A1 (en) | 2000-08-09 |
US6428805B1 (en) | 2002-08-06 |
EP1025859B1 (en) | 2006-06-28 |
WO2000012136A1 (fr) | 2000-03-09 |
PT1025859E (pt) | 2006-10-31 |
CA2307607C (en) | 2008-02-05 |
KR100611025B1 (ko) | 2006-08-10 |
ATE331532T1 (de) | 2006-07-15 |
KR20010031431A (ko) | 2001-04-16 |
DE69932144T8 (de) | 2007-10-04 |
DE69932144T2 (de) | 2007-06-06 |
AU762145C (en) | 2005-03-17 |
ES2263282T3 (es) | 2006-12-01 |
DE69932144D1 (de) | 2006-08-10 |
CN1160127C (zh) | 2004-08-04 |
JP4338313B2 (ja) | 2009-10-07 |
CA2307607A1 (en) | 2000-03-09 |
EP1025859A4 (en) | 2002-10-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1025859T3 (da) | Pulverformige pernasale præparater | |
DE69931925D1 (de) | 2-chinolonen enthaltende arzneimittel | |
IL110482A (en) | 1-benzenesulfonyl-1,3-dihydroindol-2-one derivatives their preparation and pharmaceutical compositions containing them | |
IL138899A0 (en) | Amidene derivatives and pharmaceutical compositions containing the same | |
IL139934A0 (en) | Pyrrole substituted 2-indolinone derivatives and pharmaceutical compositions containing the same | |
IL140862A0 (en) | Thiobenzimidazole derivatives and pharmaceutical compositions containing the same | |
ATE238812T1 (de) | Voriconazol-enthaltende pharmazeutische zubereitungen | |
IL131319A0 (en) | 3-Piperidyl-4- oxoquinazoline derivatives and medicinal compositions containing the same | |
IL143920A0 (en) | 3-heteroarylidenyl-2-indolinone derivatives and pharmaceutical compositions containing the same | |
DE10084671T1 (de) | Pharmazeutische Zusammensetzungen | |
IL141080A0 (en) | Disubstituted maleimide derivatives and pharmaceutical compositions containing the same | |
HK1036974A1 (en) | Indole derivatives and medicinal compositions containing the same. | |
HUP0105075A3 (en) | 3,3-biarylpiperidine and 2,2-biarylmorpholine derivatives, their use and pharmaceutical compositions containing them | |
IL152978A0 (en) | Macromolecular drug complexes and compositions containing the same | |
ATE243517T1 (de) | Einschlusskomplexe von dehydroepiandrosteron und korrespondierende pharmazeutische zusammenstellungen | |
IL134538A (en) | Lactacystin derivatives and pharmaceutical compositions containing the same | |
ATE245028T1 (de) | Trimegestone enthaltende pharmazeutische zusammensetzungen | |
AU3410099A (en) | Pharmaceutical compositions containing melatonin inclusion complexes | |
TR200003357T2 (tr) | Efervesan preparatlar. | |
FR2779429B1 (fr) | Derives d'oxindole, leurs preparations et leurs applications en therapeutique | |
IL136045A0 (en) | Pyridylpyrrole derivatives and pharmaceutical compositions containing the same | |
EE04347B1 (et) | 8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, neid sisaldav ravim ja farmatseutiline kompositsioon | |
ZA982457B (en) | Pharmaceutical compositions containing propanaminde derivatives and cyclodextrin | |
MXPA01011296A (es) | Composiciones contraceptivas que contienen derivados de indolina y agentes progestacionales. | |
HUP0002958A3 (en) | Fungicidal 4-cyano-4-deformyl-sordaricin derivatives, pharmaceutical and agricultural compositions containing the same |