DE10084671T1 - Pharmazeutische Zusammensetzungen - Google Patents

Pharmazeutische Zusammensetzungen

Info

Publication number
DE10084671T1
DE10084671T1 DE10084671T DE10084671T DE10084671T1 DE 10084671 T1 DE10084671 T1 DE 10084671T1 DE 10084671 T DE10084671 T DE 10084671T DE 10084671 T DE10084671 T DE 10084671T DE 10084671 T1 DE10084671 T1 DE 10084671T1
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
cyclosporin
carrier medium
provides composition
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10084671T
Other languages
English (en)
Inventor
Michael Ambuehl
Barbara Lueckel
Barbara Haeberlin
Armin Meinzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Pharma GmbH
Novartis AG
Original Assignee
Novartis Erfindungen Verwaltungs GmbH
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Erfindungen Verwaltungs GmbH, Novartis AG filed Critical Novartis Erfindungen Verwaltungs GmbH
Publication of DE10084671T1 publication Critical patent/DE10084671T1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE10084671T 1999-05-28 2000-05-26 Pharmazeutische Zusammensetzungen Withdrawn DE10084671T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9912476.0A GB9912476D0 (en) 1999-05-28 1999-05-28 Organic compounds
PCT/EP2000/004829 WO2000072867A2 (en) 1999-05-28 2000-05-26 Substantially oil-free cyclosporin compositions

Publications (1)

Publication Number Publication Date
DE10084671T1 true DE10084671T1 (de) 2002-06-06

Family

ID=10854362

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10084671T Withdrawn DE10084671T1 (de) 1999-05-28 2000-05-26 Pharmazeutische Zusammensetzungen
DE60019100T Expired - Fee Related DE60019100T2 (de) 1999-05-28 2000-05-26 Im wesentlichen ölfreie cyclosporin zusammensetzungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60019100T Expired - Fee Related DE60019100T2 (de) 1999-05-28 2000-05-26 Im wesentlichen ölfreie cyclosporin zusammensetzungen

Country Status (26)

Country Link
US (2) US6432445B1 (de)
EP (1) EP1181035B1 (de)
JP (1) JP2003500454A (de)
KR (1) KR20010111587A (de)
CN (1) CN1353613A (de)
AT (1) ATE291926T1 (de)
AU (1) AU765935B2 (de)
BR (1) BR0011030A (de)
CA (1) CA2371247A1 (de)
CZ (1) CZ20014214A3 (de)
DE (2) DE10084671T1 (de)
ES (1) ES2239605T3 (de)
GB (2) GB9912476D0 (de)
HK (1) HK1045642B (de)
HU (1) HUP0201372A3 (de)
IL (1) IL146186A0 (de)
MX (1) MXPA01012222A (de)
NO (1) NO20015785L (de)
NZ (1) NZ515154A (de)
PL (1) PL199591B1 (de)
PT (1) PT1181035E (de)
RU (1) RU2249461C2 (de)
SK (1) SK285471B6 (de)
TR (1) TR200103276T2 (de)
WO (1) WO2000072867A2 (de)
ZA (1) ZA200109658B (de)

Families Citing this family (24)

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CN1246058A (zh) * 1997-01-30 2000-03-01 诺瓦提斯公司 包含环孢菌素a的无油药物组合物
GB9912476D0 (en) 1999-05-28 1999-07-28 Novartis Ag Organic compounds
AR033711A1 (es) * 2001-05-09 2004-01-07 Novartis Ag Composiciones farmaceuticas
EP1455753A1 (de) * 2001-12-20 2004-09-15 Bernard Charles Sherman Pharmazeutische zubereitungen enthaltend ein cyclosporin, einen hydrophilen emulgator und einen lipophilen emulgator
US20040115287A1 (en) * 2002-12-17 2004-06-17 Lipocine, Inc. Hydrophobic active agent compositions and methods
EP1603512A2 (de) * 2003-03-17 2005-12-14 Albany Molecular Research, Inc. Neue cyclosporine
JP2005255677A (ja) * 2004-02-12 2005-09-22 Nof Corp シクロスポリン製剤
US20060014677A1 (en) * 2004-07-19 2006-01-19 Isotechnika International Inc. Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds
EP1809656A4 (de) * 2004-09-29 2009-03-25 Amr Technology Inc Cyclosporinalkinanaloga und deren pharmazeutische anwendungen
US7511013B2 (en) * 2004-09-29 2009-03-31 Amr Technology, Inc. Cyclosporin analogues and their pharmaceutical uses
JP2008515886A (ja) * 2004-10-06 2008-05-15 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキンおよびそれらの医用薬剤としての有用性
KR20080007580A (ko) 2005-04-12 2008-01-22 엘란 파마 인터내셔널 리미티드 사이클로스포린을 함유하는 나노입자형 조절 방출 조성물
EP1874855A1 (de) * 2005-04-27 2008-01-09 Kingsplan Holdings (IRL) Limited Tensid für phenolharzschaumstoff
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
MY158809A (en) * 2010-09-22 2016-11-15 Craun Res Sdn Bhd Pharmaceutical compositions for calanolides, their derivatives and analogues, and process for producing the same
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
WO2018098501A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy

Family Cites Families (43)

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Publication number Priority date Publication date Assignee Title
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DE3225706C2 (de) 1982-07-09 1984-04-26 A. Nattermann & Cie GmbH, 5000 Köln Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen
DE3315805A1 (de) 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
GB8903804D0 (en) 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
FR2609631A1 (fr) 1987-01-15 1988-07-22 Sanofi Sa Compositions liquides stables a base de bithionol
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JPH06293633A (ja) 1993-04-05 1994-10-21 Shin Etsu Chem Co Ltd 水性腸溶性エマルジョンの製造方法
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IL115742A (en) 1994-10-26 2000-06-01 Novartis Ag Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
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CN1246058A (zh) * 1997-01-30 2000-03-01 诺瓦提斯公司 包含环孢菌素a的无油药物组合物
CN1309414C (zh) * 1997-03-12 2007-04-11 艾博特公司 用于给予环孢菌素的亲水二元体系
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NZ329929A (en) * 1998-03-09 1999-10-28 Bernard Charles Sherman Pharmaceutical emulsion preconcentrate containing cyclosporin in a solvent system containing glycerides, propylene or polyethylene glycol, a surfactant and a co-surfactant
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Also Published As

Publication number Publication date
AU765935B2 (en) 2003-10-02
TR200103276T2 (tr) 2002-05-21
WO2000072867A2 (en) 2000-12-07
US20020188134A1 (en) 2002-12-12
NZ515154A (en) 2003-08-29
HK1045642B (zh) 2005-10-28
ZA200109658B (en) 2002-08-20
PL199591B1 (pl) 2008-10-31
NO20015785D0 (no) 2001-11-27
IL146186A0 (en) 2002-07-25
CN1353613A (zh) 2002-06-12
GB2367004B (en) 2004-04-14
DE60019100T2 (de) 2006-03-23
GB2367004A (en) 2002-03-27
GB0128277D0 (en) 2002-01-16
HUP0201372A3 (en) 2002-10-28
US6432445B1 (en) 2002-08-13
PT1181035E (pt) 2005-08-31
HK1045642A1 (en) 2002-12-06
WO2000072867A3 (en) 2001-04-05
AU5810000A (en) 2000-12-18
US20020068083A1 (en) 2002-06-06
CA2371247A1 (en) 2000-12-07
RU2249461C2 (ru) 2005-04-10
NO20015785L (no) 2002-01-23
GB9912476D0 (en) 1999-07-28
US6767555B2 (en) 2004-07-27
EP1181035B1 (de) 2005-03-30
JP2003500454A (ja) 2003-01-07
MXPA01012222A (es) 2002-07-02
DE60019100D1 (de) 2005-05-04
EP1181035A2 (de) 2002-02-27
ES2239605T3 (es) 2005-10-01
SK285471B6 (sk) 2007-02-01
KR20010111587A (ko) 2001-12-19
ATE291926T1 (de) 2005-04-15
BR0011030A (pt) 2002-02-26
HUP0201372A2 (en) 2002-09-28
CZ20014214A3 (cs) 2002-03-13
SK17222001A3 (sk) 2002-03-05
PL351593A1 (en) 2003-05-05

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8130 Withdrawal