TR200103276T2 - Yeterince yağsız siklosporin kompozisyonları - Google Patents

Yeterince yağsız siklosporin kompozisyonları

Info

Publication number
TR200103276T2
TR200103276T2 TR2001/03276T TR200103276T TR200103276T2 TR 200103276 T2 TR200103276 T2 TR 200103276T2 TR 2001/03276 T TR2001/03276 T TR 2001/03276T TR 200103276 T TR200103276 T TR 200103276T TR 200103276 T2 TR200103276 T2 TR 200103276T2
Authority
TR
Turkey
Prior art keywords
skimmed
sufficiently
cyclosporine compositions
cyclosporine
compositions
Prior art date
Application number
TR2001/03276T
Other languages
English (en)
Inventor
Amb�Hl Michael
L�Ckel Barbara
Haberlin Barbara
Meinzer Armin
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of TR200103276T2 publication Critical patent/TR200103276T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)

Abstract

Bu bulus, bir siklosporin ve bir tasiyici medyum içeren kompozisyon saglar.
TR2001/03276T 1999-05-28 2000-05-26 Yeterince yağsız siklosporin kompozisyonları TR200103276T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9912476.0A GB9912476D0 (en) 1999-05-28 1999-05-28 Organic compounds

Publications (1)

Publication Number Publication Date
TR200103276T2 true TR200103276T2 (tr) 2002-05-21

Family

ID=10854362

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03276T TR200103276T2 (tr) 1999-05-28 2000-05-26 Yeterince yağsız siklosporin kompozisyonları

Country Status (26)

Country Link
US (2) US6432445B1 (tr)
EP (1) EP1181035B1 (tr)
JP (1) JP2003500454A (tr)
KR (1) KR20010111587A (tr)
CN (1) CN1353613A (tr)
AT (1) ATE291926T1 (tr)
AU (1) AU765935B2 (tr)
BR (1) BR0011030A (tr)
CA (1) CA2371247A1 (tr)
CZ (1) CZ20014214A3 (tr)
DE (2) DE60019100T2 (tr)
ES (1) ES2239605T3 (tr)
GB (2) GB9912476D0 (tr)
HK (1) HK1045642B (tr)
HU (1) HUP0201372A3 (tr)
IL (1) IL146186A0 (tr)
MX (1) MXPA01012222A (tr)
NO (1) NO20015785L (tr)
NZ (1) NZ515154A (tr)
PL (1) PL199591B1 (tr)
PT (1) PT1181035E (tr)
RU (1) RU2249461C2 (tr)
SK (1) SK285471B6 (tr)
TR (1) TR200103276T2 (tr)
WO (1) WO2000072867A2 (tr)
ZA (1) ZA200109658B (tr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0988046B1 (en) * 1997-01-30 2004-09-15 Novartis AG Oil-free pharmaceutical compositions containing cyclosporin a
GB9912476D0 (en) * 1999-05-28 1999-07-28 Novartis Ag Organic compounds
AR033711A1 (es) * 2001-05-09 2004-01-07 Novartis Ag Composiciones farmaceuticas
JP2005513096A (ja) * 2001-12-20 2005-05-12 チャールズ シャーマン,バーナード シクロスポリン、親水性界面活性剤及び親油性界面活性剤を含んで成る医薬組成物
US20040115287A1 (en) * 2002-12-17 2004-06-17 Lipocine, Inc. Hydrophobic active agent compositions and methods
JP2006524232A (ja) * 2003-03-17 2006-10-26 アルバニー モレキュラー リサーチ インコーポレーティッド 新規サイクロスポリン
JP2005255677A (ja) * 2004-02-12 2005-09-22 Nof Corp シクロスポリン製剤
US20060014677A1 (en) * 2004-07-19 2006-01-19 Isotechnika International Inc. Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds
US7511013B2 (en) * 2004-09-29 2009-03-31 Amr Technology, Inc. Cyclosporin analogues and their pharmaceutical uses
EP1809656A4 (en) * 2004-09-29 2009-03-25 Amr Technology Inc CYCLOSPORINAL KINANALOGA AND ITS PHARMACEUTICAL APPLICATIONS
EP1812037A4 (en) * 2004-10-06 2009-11-11 Amr Technology Inc ALKYNES OF CYCLOSPORINE AND THEIR USEFUL AS PHARMACEUTICAL AGENTS
JP2008535921A (ja) 2005-04-12 2008-09-04 エラン・ファルマ・インターナショナル・リミテッド シクロスポリンを含むナノ粒子および放出調節された組成物
GB2440493B (en) * 2005-04-27 2010-03-10 Kingspan Holdings Surfactant for phenolic foam
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
MY158809A (en) * 2010-09-22 2016-11-15 Craun Res Sdn Bhd Pharmaceutical compositions for calanolides, their derivatives and analogues, and process for producing the same
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
US20170246187A1 (en) 2014-08-28 2017-08-31 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
EP3544614A4 (en) 2016-11-28 2020-08-05 Lipocine Inc. ORAL TESTOSTERONE UNDECANOATE THERAPY

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7012460A (tr) 1970-08-22 1972-02-24
DE3225706C2 (de) 1982-07-09 1984-04-26 A. Nattermann & Cie GmbH, 5000 Köln Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen
DE3315805A1 (de) 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
GB8903804D0 (en) 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
FR2609631A1 (fr) 1987-01-15 1988-07-22 Sanofi Sa Compositions liquides stables a base de bithionol
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US5342625A (en) 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
US6007840A (en) 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
DE3908047A1 (de) 1989-03-13 1990-09-20 Desitin Arzneimittel Gmbh Hochdisperse pharmazeutische zusammensetzung
US5266590A (en) 1989-12-11 1993-11-30 Isp Investments Inc. Cold stabilization of aqueous microemulsions of a water-insoluble agriculturally active compound
US5389688A (en) 1989-12-11 1995-02-14 Isp Investments Inc. Water based microemulsion formulations
US5283229A (en) 1989-12-11 1994-02-01 Isp Investments Inc. Delivery system for agricultural chemicals
US5110606A (en) 1990-11-13 1992-05-05 Affinity Biotech, Inc. Non-aqueous microemulsions for drug delivery
DE69229169T2 (de) 1991-02-12 1999-11-18 Isp Investments Inc Stabilisierung von mikroemulsionen durch verwendung hydrophober saurer puffer
US5300529A (en) 1991-02-12 1994-04-05 Isp Investments Inc. Stable, clear, efficacious aqueous microemulsion compositions containing a high loading of a water-insoluble, agriculturally active chemical
US6022853A (en) * 1991-08-30 2000-02-08 Creative Biomolecules, Inc. Morphogen-enriched dietary composition
GB9225540D0 (en) 1992-12-07 1993-01-27 Ici Plc Cleaning compositions
JPH06293633A (ja) 1993-04-05 1994-10-21 Shin Etsu Chem Co Ltd 水性腸溶性エマルジョンの製造方法
CH686761A5 (de) 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
GB2278780B (en) 1993-05-27 1998-10-14 Sandoz Ltd Macrolide formulations
FR2710535B1 (fr) 1993-09-30 1995-11-24 Gattefosse Ets Sa Composition à usage pharmaceutique ou cosmétique apte à former une microémulsion.
DE4337041A1 (de) 1993-10-29 1995-05-04 Henkel Kgaa Verfahren zur Herstellung in Öl-in-Wasser-Emulsionen
WO1995022343A1 (fr) 1994-02-17 1995-08-24 Shiseido Company, Ltd. Composition d'emulsion a base de cyclosporine
MY129435A (en) 1994-10-26 2007-04-30 Novartis Ag Pharmaceutical microemulsion preconcentrates
US5691289A (en) 1994-11-17 1997-11-25 Kay Chemical Company Cleaning compositions and methods of using the same
HU215966B (hu) 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
CA2221145A1 (en) 1995-05-19 1996-11-21 Abbott Laboratories Self-emulsifying formulations of lipophilic drugs
SE9503143D0 (sv) 1995-09-12 1995-09-12 Astra Ab New preparation
DE19537836A1 (de) 1995-10-11 1997-04-17 Henkel Kgaa Aerosolemulsionen
KR970064620A (ko) 1996-03-05 1997-10-13 임성기 사이클로스포린-함유 외용약제 조성물
DE19615271A1 (de) 1996-04-18 1997-10-23 Huels Chemische Werke Ag Tensidhaltige Reinigungsmittel in Form einer Mikroemulsion
KR980008239A (ko) 1996-07-26 1998-04-30 김충환 사이클로스포린-함유 약학적 조성물
EP0988046B1 (en) * 1997-01-30 2004-09-15 Novartis AG Oil-free pharmaceutical compositions containing cyclosporin a
CA2284000C (en) * 1997-03-12 2012-01-03 Abbott Laboratories Hydrophilic binary systems for the administration of cyclosporine
EP0973502A1 (en) 1997-03-12 2000-01-26 Abbott Laboratories Lipophilic binary systems for the administration of lipophilic compounds
US6028067A (en) 1997-12-05 2000-02-22 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
US6063762A (en) 1997-12-05 2000-05-16 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
WO1999029335A1 (en) 1997-12-05 1999-06-17 Chong Kun Dang Corp. Pharmaceutical composition containing cyclosporin
CA2313024C (en) 1997-12-10 2008-06-03 Severson, Mary L. Pharmaceutical compositions containing an omega-3 fatty acid oil
NZ329929A (en) * 1998-03-09 1999-10-28 Bernard Charles Sherman Pharmaceutical emulsion preconcentrate containing cyclosporin in a solvent system containing glycerides, propylene or polyethylene glycol, a surfactant and a co-surfactant
DE69939335D1 (de) * 1998-12-30 2008-09-25 Dexcel Ltd Dispergierbares konzentrat zur verabreichung von cyclosporin
GB9912476D0 (en) * 1999-05-28 1999-07-28 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
US6767555B2 (en) 2004-07-27
IL146186A0 (en) 2002-07-25
GB2367004A (en) 2002-03-27
MXPA01012222A (es) 2002-07-02
WO2000072867A3 (en) 2001-04-05
JP2003500454A (ja) 2003-01-07
DE60019100D1 (de) 2005-05-04
NO20015785D0 (no) 2001-11-27
ES2239605T3 (es) 2005-10-01
CZ20014214A3 (cs) 2002-03-13
EP1181035A2 (en) 2002-02-27
EP1181035B1 (en) 2005-03-30
HK1045642A1 (en) 2002-12-06
US20020188134A1 (en) 2002-12-12
DE10084671T1 (de) 2002-06-06
PL199591B1 (pl) 2008-10-31
RU2249461C2 (ru) 2005-04-10
SK285471B6 (sk) 2007-02-01
SK17222001A3 (sk) 2002-03-05
GB0128277D0 (en) 2002-01-16
AU765935B2 (en) 2003-10-02
GB2367004B (en) 2004-04-14
PT1181035E (pt) 2005-08-31
AU5810000A (en) 2000-12-18
US20020068083A1 (en) 2002-06-06
KR20010111587A (ko) 2001-12-19
HUP0201372A2 (en) 2002-09-28
WO2000072867A2 (en) 2000-12-07
CN1353613A (zh) 2002-06-12
NO20015785L (no) 2002-01-23
CA2371247A1 (en) 2000-12-07
BR0011030A (pt) 2002-02-26
DE60019100T2 (de) 2006-03-23
GB9912476D0 (en) 1999-07-28
HUP0201372A3 (en) 2002-10-28
US6432445B1 (en) 2002-08-13
ZA200109658B (en) 2002-08-20
NZ515154A (en) 2003-08-29
PL351593A1 (en) 2003-05-05
ATE291926T1 (de) 2005-04-15
HK1045642B (zh) 2005-10-28

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