PT1181035E - Composicoes de ciclosporina substancialmente isentas de oleo - Google Patents

Composicoes de ciclosporina substancialmente isentas de oleo

Info

Publication number
PT1181035E
PT1181035E PT00943742T PT00943742T PT1181035E PT 1181035 E PT1181035 E PT 1181035E PT 00943742 T PT00943742 T PT 00943742T PT 00943742 T PT00943742 T PT 00943742T PT 1181035 E PT1181035 E PT 1181035E
Authority
PT
Portugal
Prior art keywords
free
substantially oil
compositions substantially
cyclosporine compositions
cyclosporine
Prior art date
Application number
PT00943742T
Other languages
English (en)
Inventor
Lueckel Barbara
Haeberlin Barbara
Ambuehl Michael
Meinzer Armin
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT1181035E publication Critical patent/PT1181035E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT00943742T 1999-05-28 2000-05-26 Composicoes de ciclosporina substancialmente isentas de oleo PT1181035E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9912476.0A GB9912476D0 (en) 1999-05-28 1999-05-28 Organic compounds

Publications (1)

Publication Number Publication Date
PT1181035E true PT1181035E (pt) 2005-08-31

Family

ID=10854362

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00943742T PT1181035E (pt) 1999-05-28 2000-05-26 Composicoes de ciclosporina substancialmente isentas de oleo

Country Status (26)

Country Link
US (2) US6432445B1 (pt)
EP (1) EP1181035B1 (pt)
JP (1) JP2003500454A (pt)
KR (1) KR20010111587A (pt)
CN (1) CN1353613A (pt)
AT (1) ATE291926T1 (pt)
AU (1) AU765935B2 (pt)
BR (1) BR0011030A (pt)
CA (1) CA2371247A1 (pt)
CZ (1) CZ20014214A3 (pt)
DE (2) DE10084671T1 (pt)
ES (1) ES2239605T3 (pt)
GB (2) GB9912476D0 (pt)
HK (1) HK1045642B (pt)
HU (1) HUP0201372A3 (pt)
IL (1) IL146186A0 (pt)
MX (1) MXPA01012222A (pt)
NO (1) NO20015785L (pt)
NZ (1) NZ515154A (pt)
PL (1) PL199591B1 (pt)
PT (1) PT1181035E (pt)
RU (1) RU2249461C2 (pt)
SK (1) SK285471B6 (pt)
TR (1) TR200103276T2 (pt)
WO (1) WO2000072867A2 (pt)
ZA (1) ZA200109658B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG115386A1 (en) * 1997-01-30 2005-10-28 Novartis Ag Hard gelatine capsules containing pharmaceutical compositions substantially free of any oil
GB9912476D0 (en) * 1999-05-28 1999-07-28 Novartis Ag Organic compounds
AR033711A1 (es) * 2001-05-09 2004-01-07 Novartis Ag Composiciones farmaceuticas
US20050129718A1 (en) * 2001-12-20 2005-06-16 Sherman Bernard C. Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant
US20040115287A1 (en) * 2002-12-17 2004-06-17 Lipocine, Inc. Hydrophobic active agent compositions and methods
AU2004222306A1 (en) * 2003-03-17 2004-09-30 Albany Molecular Research, Inc. Novel cyclosporins
JP2005255677A (ja) * 2004-02-12 2005-09-22 Nof Corp シクロスポリン製剤
US20060014677A1 (en) * 2004-07-19 2006-01-19 Isotechnika International Inc. Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds
US7511013B2 (en) * 2004-09-29 2009-03-31 Amr Technology, Inc. Cyclosporin analogues and their pharmaceutical uses
JP2008514701A (ja) * 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキン類似体およびそれらの薬学的使用
JP2008515886A (ja) * 2004-10-06 2008-05-15 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキンおよびそれらの医用薬剤としての有用性
BRPI0609071A2 (pt) 2005-04-12 2010-11-16 Elan Pharma Int Ltd composicão estável de ciclosporina nanoparticulada, método para preparar uma ciclosporina nanoparticulada, uso da composição de ciclosporina nanoparticulada estável, e, composição de liberação controlada
GB2440493B (en) * 2005-04-27 2010-03-10 Kingspan Holdings Surfactant for phenolic foam
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
MY158809A (en) * 2010-09-22 2016-11-15 Craun Res Sdn Bhd Pharmaceutical compositions for calanolides, their derivatives and analogues, and process for producing the same
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
EP3544614A4 (en) 2016-11-28 2020-08-05 Lipocine Inc. ORAL TESTOSTERONE UNDECANOATE THERAPY

Family Cites Families (43)

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Publication number Priority date Publication date Assignee Title
NL7012460A (pt) 1970-08-22 1972-02-24
DE3225706C2 (de) 1982-07-09 1984-04-26 A. Nattermann & Cie GmbH, 5000 Köln Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen
DE3315805A1 (de) 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
GB8903804D0 (en) 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
FR2609631A1 (fr) 1987-01-15 1988-07-22 Sanofi Sa Compositions liquides stables a base de bithionol
US5342625A (en) 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
US6007840A (en) 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
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US5300529A (en) 1991-02-12 1994-04-05 Isp Investments Inc. Stable, clear, efficacious aqueous microemulsion compositions containing a high loading of a water-insoluble, agriculturally active chemical
EP0574492B1 (en) 1991-02-12 1999-05-12 Isp Investments Inc. Stabilization of microemulsions using hydrophobic acid buffers
US6022853A (en) * 1991-08-30 2000-02-08 Creative Biomolecules, Inc. Morphogen-enriched dietary composition
GB9225540D0 (en) 1992-12-07 1993-01-27 Ici Plc Cleaning compositions
JPH06293633A (ja) 1993-04-05 1994-10-21 Shin Etsu Chem Co Ltd 水性腸溶性エマルジョンの製造方法
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SG115386A1 (en) * 1997-01-30 2005-10-28 Novartis Ag Hard gelatine capsules containing pharmaceutical compositions substantially free of any oil
JP2001515491A (ja) 1997-03-12 2001-09-18 アボツト・ラボラトリーズ 親油性化合物の投与のための親油性二成分系
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EP1039893B1 (en) 1997-12-10 2011-02-02 Cyclosporine Therapeutics Limited Pharmaceutical compositions containing an omega-3 fatty acid oil
NZ329929A (en) * 1998-03-09 1999-10-28 Bernard Charles Sherman Pharmaceutical emulsion preconcentrate containing cyclosporin in a solvent system containing glycerides, propylene or polyethylene glycol, a surfactant and a co-surfactant
PT1154759E (pt) * 1998-12-30 2008-11-20 Dexcel Ltd Concentrado dispersível para administração de ciclosporina
GB9912476D0 (en) * 1999-05-28 1999-07-28 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
DE60019100T2 (de) 2006-03-23
US6432445B1 (en) 2002-08-13
KR20010111587A (ko) 2001-12-19
WO2000072867A2 (en) 2000-12-07
US6767555B2 (en) 2004-07-27
IL146186A0 (en) 2002-07-25
CZ20014214A3 (cs) 2002-03-13
ZA200109658B (en) 2002-08-20
SK17222001A3 (sk) 2002-03-05
ATE291926T1 (de) 2005-04-15
RU2249461C2 (ru) 2005-04-10
MXPA01012222A (es) 2002-07-02
HUP0201372A3 (en) 2002-10-28
GB9912476D0 (en) 1999-07-28
US20020188134A1 (en) 2002-12-12
GB2367004B (en) 2004-04-14
NO20015785L (no) 2002-01-23
AU5810000A (en) 2000-12-18
GB0128277D0 (en) 2002-01-16
GB2367004A (en) 2002-03-27
US20020068083A1 (en) 2002-06-06
NZ515154A (en) 2003-08-29
BR0011030A (pt) 2002-02-26
JP2003500454A (ja) 2003-01-07
CN1353613A (zh) 2002-06-12
DE60019100D1 (de) 2005-05-04
NO20015785D0 (no) 2001-11-27
HUP0201372A2 (en) 2002-09-28
HK1045642B (zh) 2005-10-28
DE10084671T1 (de) 2002-06-06
PL351593A1 (en) 2003-05-05
TR200103276T2 (tr) 2002-05-21
AU765935B2 (en) 2003-10-02
PL199591B1 (pl) 2008-10-31
EP1181035B1 (en) 2005-03-30
ES2239605T3 (es) 2005-10-01
WO2000072867A3 (en) 2001-04-05
EP1181035A2 (en) 2002-02-27
CA2371247A1 (en) 2000-12-07
HK1045642A1 (en) 2002-12-06
SK285471B6 (sk) 2007-02-01

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