NO20015785L - I dets vesentlige oljefrie cyklosporinblandinger - Google Patents

I dets vesentlige oljefrie cyklosporinblandinger

Info

Publication number
NO20015785L
NO20015785L NO20015785A NO20015785A NO20015785L NO 20015785 L NO20015785 L NO 20015785L NO 20015785 A NO20015785 A NO 20015785A NO 20015785 A NO20015785 A NO 20015785A NO 20015785 L NO20015785 L NO 20015785L
Authority
NO
Norway
Prior art keywords
mixtures
essential oil
cyclosporin
free cyclosporin
free
Prior art date
Application number
NO20015785A
Other languages
English (en)
Norwegian (no)
Other versions
NO20015785D0 (no
Inventor
Michael Ambuehl
Barbara Lueckel
Barbara Haeberlin
Armin Meinzer
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20015785D0 publication Critical patent/NO20015785D0/no
Publication of NO20015785L publication Critical patent/NO20015785L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20015785A 1999-05-28 2001-11-27 I dets vesentlige oljefrie cyklosporinblandinger NO20015785L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9912476.0A GB9912476D0 (en) 1999-05-28 1999-05-28 Organic compounds
PCT/EP2000/004829 WO2000072867A2 (en) 1999-05-28 2000-05-26 Substantially oil-free cyclosporin compositions

Publications (2)

Publication Number Publication Date
NO20015785D0 NO20015785D0 (no) 2001-11-27
NO20015785L true NO20015785L (no) 2002-01-23

Family

ID=10854362

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015785A NO20015785L (no) 1999-05-28 2001-11-27 I dets vesentlige oljefrie cyklosporinblandinger

Country Status (26)

Country Link
US (2) US6432445B1 (tr)
EP (1) EP1181035B1 (tr)
JP (1) JP2003500454A (tr)
KR (1) KR20010111587A (tr)
CN (1) CN1353613A (tr)
AT (1) ATE291926T1 (tr)
AU (1) AU765935B2 (tr)
BR (1) BR0011030A (tr)
CA (1) CA2371247A1 (tr)
CZ (1) CZ20014214A3 (tr)
DE (2) DE10084671T1 (tr)
ES (1) ES2239605T3 (tr)
GB (2) GB9912476D0 (tr)
HK (1) HK1045642B (tr)
HU (1) HUP0201372A3 (tr)
IL (1) IL146186A0 (tr)
MX (1) MXPA01012222A (tr)
NO (1) NO20015785L (tr)
NZ (1) NZ515154A (tr)
PL (1) PL199591B1 (tr)
PT (1) PT1181035E (tr)
RU (1) RU2249461C2 (tr)
SK (1) SK285471B6 (tr)
TR (1) TR200103276T2 (tr)
WO (1) WO2000072867A2 (tr)
ZA (1) ZA200109658B (tr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2211047C2 (ru) * 1997-01-30 2003-08-27 Новартис Аг Желатиновые капсулы с твердым покрытием, включающие фармацевтические композиции, практически не содержащие масел
GB9912476D0 (en) 1999-05-28 1999-07-28 Novartis Ag Organic compounds
AR033711A1 (es) * 2001-05-09 2004-01-07 Novartis Ag Composiciones farmaceuticas
WO2003053404A1 (en) * 2001-12-20 2003-07-03 Bernard Charles Sherman Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant
US20040115287A1 (en) * 2002-12-17 2004-06-17 Lipocine, Inc. Hydrophobic active agent compositions and methods
WO2004082629A2 (en) * 2003-03-17 2004-09-30 Albany Molecular Research, Inc. Novel cyclosporins
JP2005255677A (ja) * 2004-02-12 2005-09-22 Nof Corp シクロスポリン製剤
US20060014677A1 (en) * 2004-07-19 2006-01-19 Isotechnika International Inc. Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds
EP1809656A4 (en) * 2004-09-29 2009-03-25 Amr Technology Inc CYCLOSPORINAL KINANALOGA AND ITS PHARMACEUTICAL APPLICATIONS
EP1804823A4 (en) * 2004-09-29 2010-06-09 Amr Technology Inc NEW CYCLOSPORIN ANALOGUE AND ITS PHARMACEUTICAL APPLICATIONS
WO2006041631A2 (en) * 2004-10-06 2006-04-20 Amr Technology, Inc. Novel cyclosporin alkynes and their utility as pharmaceutical agents
CA2603084A1 (en) 2005-04-12 2006-10-19 Elan Pharma International Limited Nanoparticulate and controlled release compositions comprising cyclosporine
EP1874855A1 (en) * 2005-04-27 2008-01-09 Kingsplan Holdings (IRL) Limited Surfactant for phenolic foam
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
MY158809A (en) * 2010-09-22 2016-11-15 Craun Res Sdn Bhd Pharmaceutical compositions for calanolides, their derivatives and analogues, and process for producing the same
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
US20170246187A1 (en) 2014-08-28 2017-08-31 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
CA3078723A1 (en) 2016-11-28 2018-05-31 Nachiappan Chidambaram Oral testosterone undecanoate therapy

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7012460A (tr) 1970-08-22 1972-02-24
DE3225706C2 (de) 1982-07-09 1984-04-26 A. Nattermann & Cie GmbH, 5000 Köln Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen
DE3315805A1 (de) 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
GB8903804D0 (en) 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
FR2609631A1 (fr) 1987-01-15 1988-07-22 Sanofi Sa Compositions liquides stables a base de bithionol
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
US6007840A (en) 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US5342625A (en) 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
DE3908047A1 (de) 1989-03-13 1990-09-20 Desitin Arzneimittel Gmbh Hochdisperse pharmazeutische zusammensetzung
US5266590A (en) 1989-12-11 1993-11-30 Isp Investments Inc. Cold stabilization of aqueous microemulsions of a water-insoluble agriculturally active compound
US5389688A (en) 1989-12-11 1995-02-14 Isp Investments Inc. Water based microemulsion formulations
US5283229A (en) 1989-12-11 1994-02-01 Isp Investments Inc. Delivery system for agricultural chemicals
US5110606A (en) 1990-11-13 1992-05-05 Affinity Biotech, Inc. Non-aqueous microemulsions for drug delivery
US5300529A (en) 1991-02-12 1994-04-05 Isp Investments Inc. Stable, clear, efficacious aqueous microemulsion compositions containing a high loading of a water-insoluble, agriculturally active chemical
CA2097707A1 (en) 1991-02-12 1992-08-13 Kolazi S. Narayanan Stabilization of microemulsions using hydrophobic acid buffers
US6022853A (en) * 1991-08-30 2000-02-08 Creative Biomolecules, Inc. Morphogen-enriched dietary composition
GB9225540D0 (en) 1992-12-07 1993-01-27 Ici Plc Cleaning compositions
JPH06293633A (ja) 1993-04-05 1994-10-21 Shin Etsu Chem Co Ltd 水性腸溶性エマルジョンの製造方法
CH686761A5 (de) 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
GB2278780B (en) 1993-05-27 1998-10-14 Sandoz Ltd Macrolide formulations
FR2710535B1 (fr) 1993-09-30 1995-11-24 Gattefosse Ets Sa Composition à usage pharmaceutique ou cosmétique apte à former une microémulsion.
DE4337041A1 (de) 1993-10-29 1995-05-04 Henkel Kgaa Verfahren zur Herstellung in Öl-in-Wasser-Emulsionen
EP0694308A4 (en) 1994-02-17 1997-09-10 Shiseido Co Ltd CYCLOSPORIN EMULSION COMPOSITION
IL129547A (en) 1994-10-26 2001-01-11 Novartis Ag Pharmaceutical compositions comprising a macrolide and an acid
US5691289A (en) 1994-11-17 1997-11-25 Kay Chemical Company Cleaning compositions and methods of using the same
HU215966B (hu) 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
EP0825849A1 (en) 1995-05-19 1998-03-04 Abbott Laboratories Self-emulsifying formulations of lipophilic drugs
SE9503143D0 (sv) 1995-09-12 1995-09-12 Astra Ab New preparation
DE19537836A1 (de) 1995-10-11 1997-04-17 Henkel Kgaa Aerosolemulsionen
KR970064620A (ko) 1996-03-05 1997-10-13 임성기 사이클로스포린-함유 외용약제 조성물
DE19615271A1 (de) 1996-04-18 1997-10-23 Huels Chemische Werke Ag Tensidhaltige Reinigungsmittel in Form einer Mikroemulsion
KR980008239A (ko) 1996-07-26 1998-04-30 김충환 사이클로스포린-함유 약학적 조성물
RU2211047C2 (ru) * 1997-01-30 2003-08-27 Новартис Аг Желатиновые капсулы с твердым покрытием, включающие фармацевтические композиции, практически не содержащие масел
HU228855B1 (en) 1997-03-12 2013-06-28 Abbott Lab Hydrophilic binary systems for the administration of cyclosporine
EP0973502A1 (en) 1997-03-12 2000-01-26 Abbott Laboratories Lipophilic binary systems for the administration of lipophilic compounds
US6063762A (en) 1997-12-05 2000-05-16 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
US6028067A (en) 1997-12-05 2000-02-22 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
AU1509799A (en) 1997-12-05 1999-06-28 Chong Kun Dang Corporation Pharmaceutical composition containing cyclosporin
JP4761093B2 (ja) 1997-12-10 2011-08-31 シクロスポリン セラポイティクス リミテッド オメガ−３脂肪酸油を含む医薬組成物
NZ329929A (en) * 1998-03-09 1999-10-28 Bernard Charles Sherman Pharmaceutical emulsion preconcentrate containing cyclosporin in a solvent system containing glycerides, propylene or polyethylene glycol, a surfactant and a co-surfactant
US7026290B1 (en) * 1998-12-30 2006-04-11 Dexcel Ltd. Dispersible concentrate for the delivery of cyclosprin
GB9912476D0 (en) 1999-05-28 1999-07-28 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
CA2371247A1 (en) 2000-12-07
HUP0201372A3 (en) 2002-10-28
PL199591B1 (pl) 2008-10-31
DE60019100D1 (de) 2005-05-04
DE60019100T2 (de) 2006-03-23
MXPA01012222A (es) 2002-07-02
AU5810000A (en) 2000-12-18
PL351593A1 (en) 2003-05-05
GB2367004A (en) 2002-03-27
US6432445B1 (en) 2002-08-13
JP2003500454A (ja) 2003-01-07
GB9912476D0 (en) 1999-07-28
GB0128277D0 (en) 2002-01-16
HK1045642A1 (en) 2002-12-06
ES2239605T3 (es) 2005-10-01
SK285471B6 (sk) 2007-02-01
CN1353613A (zh) 2002-06-12
HUP0201372A2 (en) 2002-09-28
DE10084671T1 (de) 2002-06-06
US6767555B2 (en) 2004-07-27
US20020068083A1 (en) 2002-06-06
EP1181035B1 (en) 2005-03-30
EP1181035A2 (en) 2002-02-27
WO2000072867A3 (en) 2001-04-05
KR20010111587A (ko) 2001-12-19
PT1181035E (pt) 2005-08-31
GB2367004B (en) 2004-04-14
BR0011030A (pt) 2002-02-26
AU765935B2 (en) 2003-10-02
HK1045642B (zh) 2005-10-28
TR200103276T2 (tr) 2002-05-21
NO20015785D0 (no) 2001-11-27
RU2249461C2 (ru) 2005-04-10
SK17222001A3 (sk) 2002-03-05
CZ20014214A3 (cs) 2002-03-13
NZ515154A (en) 2003-08-29
ZA200109658B (en) 2002-08-20
IL146186A0 (en) 2002-07-25
WO2000072867A2 (en) 2000-12-07
US20020188134A1 (en) 2002-12-12
ATE291926T1 (de) 2005-04-15

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