TR199900531A3 - Pirazolopirimidinler ve pirazolotriazinler. - Google Patents

Pirazolopirimidinler ve pirazolotriazinler.

Info

Publication number
TR199900531A3
TR199900531A3 TR1999/00531A TR9900531A TR199900531A3 TR 199900531 A3 TR199900531 A3 TR 199900531A3 TR 1999/00531 A TR1999/00531 A TR 1999/00531A TR 9900531 A TR9900531 A TR 9900531A TR 199900531 A3 TR199900531 A3 TR 199900531A3
Authority
TR
Turkey
Prior art keywords
pirazolotriazines
pirazolopyrimidines
Prior art date
Application number
TR1999/00531A
Other languages
English (en)
Other versions
TR199900531A2 (tr
Inventor
Boes Michael
Riemer Claus
Stadler Heinz
Original Assignee
F.Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag
Publication of TR199900531A2 publication Critical patent/TR199900531A2/tr
Publication of TR199900531A3 publication Critical patent/TR199900531A3/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
TR1999/00531A 1998-03-11 1999-03-11 Pirazolopirimidinler ve pirazolotriazinler. TR199900531A3 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98104346 1998-03-11

Publications (2)

Publication Number Publication Date
TR199900531A2 TR199900531A2 (tr) 1999-10-21
TR199900531A3 true TR199900531A3 (tr) 1999-10-21

Family

ID=8231568

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/00531A TR199900531A3 (tr) 1998-03-11 1999-03-11 Pirazolopirimidinler ve pirazolotriazinler.

Country Status (34)

Country Link
US (1) US6194410B1 (tr)
EP (1) EP0941994B1 (tr)
JP (1) JP3231288B2 (tr)
KR (1) KR100313181B1 (tr)
CN (1) CN1118468C (tr)
AR (1) AR016453A1 (tr)
AT (1) ATE240332T1 (tr)
AU (1) AU752408B2 (tr)
BR (1) BR9901095A (tr)
CA (1) CA2265095C (tr)
CZ (1) CZ291514B6 (tr)
DE (1) DE69907784T2 (tr)
DK (1) DK0941994T3 (tr)
ES (1) ES2198095T3 (tr)
HK (1) HK1023343A1 (tr)
HR (1) HRP990077B1 (tr)
HU (1) HUP9900589A1 (tr)
ID (1) ID23575A (tr)
IL (1) IL128869A (tr)
MA (1) MA26612A1 (tr)
MY (1) MY119536A (tr)
NO (1) NO312297B1 (tr)
NZ (1) NZ334526A (tr)
PE (1) PE20000337A1 (tr)
PL (1) PL331875A1 (tr)
PT (1) PT941994E (tr)
RU (1) RU2218340C2 (tr)
SG (1) SG78336A1 (tr)
SI (1) SI0941994T1 (tr)
TR (1) TR199900531A3 (tr)
TW (1) TW585865B (tr)
UY (1) UY25419A1 (tr)
YU (1) YU12099A (tr)
ZA (1) ZA991946B (tr)

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EP1368094B1 (en) * 2001-03-13 2007-02-28 Bristol-Myers Squibb Pharma Company 4-(2-butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl) pyrazolo- 1,5-a|-1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands
ATE353318T1 (de) 2001-06-07 2007-02-15 Hoffmann La Roche Neue indolderivate mit affinität zum 5-ht6- rezeptor
DE60212841T2 (de) 2001-06-15 2007-06-21 F. Hoffmann-La Roche Ag 4 piperazinylindolderivate mit affinität zum 5-ht6-rezeptor
US20040242589A1 (en) * 2001-08-07 2004-12-02 Bromidge Steven Mark 3-arylsulfonyl-7-piperzinyl-indoles-benzofurans and -benzothiophenes with 5-ht6 receptor affinity for treating cns disorders
PL210413B1 (pl) * 2001-12-20 2012-01-31 Wyeth Corp Pochodne indoliloalkiloaminy
US6642381B2 (en) * 2001-12-27 2003-11-04 Hoffman-La Roche Inc. Pyrimido[5,4-e][1,2,4]triazine-5,7-diamine compounds as protein tyrosine phosphatase inhibitors
GB0202679D0 (en) * 2002-02-05 2002-03-20 Glaxo Group Ltd Novel compounds
UA78999C2 (en) * 2002-06-04 2007-05-10 Wyeth Corp 1-(aminoalkyl)-3-sulfonylazaindoles as ligands of 5-hydroxytryptamine-6
US6875771B2 (en) 2002-07-26 2005-04-05 Bristol-Myers Squibb Company Pyridopyrimidine derivatives as 5-HT6 antagonists
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
WO2004074286A1 (en) * 2003-02-14 2004-09-02 Wyeth Heterocyclyl-3-sulfonylazaindole or -azaindazole derivatives as 5-hydroxytryptamine-6 ligands
KR20050115252A (ko) 2003-02-28 2005-12-07 데이진 화-마 가부시키가이샤 피라졸로[1,5-ａ]피리미딘 유도체
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KR20100119776A (ko) * 2008-01-24 2010-11-10 알라 캠, 엘엘씨 2-알킬아미노-3-아릴설포닐-사이클로알카노[ｅ 또는 ｄ]피라졸로[1,5-Ａ]피리미딘/세로토닌 5-ＨＴ6 수용체의 길항제, 이의 제조방법 및 이의 용도
RU2369600C1 (ru) * 2008-01-24 2009-10-10 Андрей Александрович Иващенко ЗАМЕЩЕННЫЕ 4-СУЛЬФОНИЛ-ПИРАЗОЛЫ И 3-СУЛЬФОНИЛ-ПИРАЗОЛО[1,5-a]ПИРИМИДИНЫ - АНТАГОНИСТЫ СЕРОТОНИНОВЫХ5-HT6 РЕЦЕПТОРОВ, АКТИВНЫЙ КОМПОНЕНТ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ЛЕКАРСТВЕННОЕ СРЕДСТВО И СПОСОБЫ ИХ ПОЛУЧЕНИЯ
KR20110000623A (ko) * 2008-01-24 2011-01-04 알라 캠, 엘엘씨 치환된 2-아미노-3-설포닐-피라졸로[1,5-ａ]피리미딘/세로토닌 5-нт6 수용체의 길항제, 이의 제조방법 및 이의 용도
RU2384581C2 (ru) 2008-05-07 2010-03-20 Андрей Александрович Иващенко ЗАМЕЩЕННЫЕ 2-АМИНО-3-СУЛЬФОНИЛ-ТЕТРАГИДРО-ПИРАЗОЛО[1,5-a]ПИРИДО-ПИРИМИДИНЫ - АНТАГОНИСТЫ СЕРОТОНИНОВЫХ 5-HT6 РЕЦЕПТОРОВ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ
EA017630B1 (ru) * 2008-10-06 2013-01-30 Андрей Александрович ИВАЩЕНКО ЗАМЕЩЕННЫЕ 3-АРИЛСУЛЬФОНИЛПИРАЗОЛО[1,5-a]ПИРИМИДИНЫ, АНТАГОНИСТЫ СЕРОТОНИНОВЫХ 5-HT-РЕЦЕПТОРОВ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ
US20120165304A1 (en) * 2008-11-27 2012-06-28 Boehringer Ingelheim International Gmbh 6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyclohept[f]indene derivatives, pharmaceutical compositions containing these compounds, their use and processes for preparing them
GB0908394D0 (en) 2009-05-15 2009-06-24 Univ Leuven Kath Novel viral replication inhibitors
GB0913636D0 (en) 2009-08-05 2009-09-16 Univ Leuven Kath Novel viral replication inhibitors
EP2640705A2 (en) 2010-11-15 2013-09-25 Katholieke Universiteit Leuven Novel antiviral compounds
RU2443697C1 (ru) 2010-12-21 2012-02-27 Александр Васильевич Иващенко Замещенные метил-амины, антагонисты серотониновых 5-ht6 рецепторов, способы получения и применения
CA2850350A1 (en) 2011-09-30 2013-04-04 Ipsen Pharma S.A.S. Macrocyclic lrrk2 kinase inhibitors
SG11201405561RA (en) 2012-03-09 2014-10-30 Lexicon Pharmaceuticals Inc PYRAZOLO[1,5-a]PYRIMIDINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE
TW201542550A (zh) * 2013-09-06 2015-11-16 Lexicon Pharmaceuticals Inc 吡唑并［１，５－ａ］嘧啶基化合物、包含彼之組合物以及使用彼之方法
TW201620911A (zh) * 2014-03-17 2016-06-16 雷西肯製藥股份有限公司 銜接子關聯激酶１之抑制劑、包含其之組成物、及其使用方法
DK3194405T3 (en) 2014-09-17 2019-04-15 Oncodesign Sa MACROCYCLIC LRRK2 KINase INHIBITORS
WO2016142855A2 (en) * 2015-03-09 2016-09-15 Aurigene Discovery Technologies Limited Pyrazolo[1,5-a][1,3,5]triazine and pyrazolo[1,5-a]pyrimidine derivatives as cdk inhibitors
WO2017052394A1 (en) * 2015-09-23 2017-03-30 Uniwersytet Jagielloński Imidazopyridine compounds and their use as 5-ht6 receptor ligands
US10947239B2 (en) 2015-11-02 2021-03-16 Janssen Pharmaceutica Nv [1,2,4]triazolo[1,5-a]pyrimidin-7-yl compound
BR112019008163A2 (pt) 2016-11-02 2019-07-09 Janssen Pharmaceutica Nv compostos de [1,2,4]triazolo[1,5-a]pirimidina como inibidores de pde2
BR112019008404A2 (pt) 2016-11-02 2019-09-17 Janssen Pharmaceutica Nv derivados de [1,2,4]triazolo[1,5-a]pirimidina como inibidores da pde2
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Also Published As

Publication number Publication date
ES2198095T3 (es) 2004-01-16
DE69907784T2 (de) 2004-03-25
SG78336A1 (en) 2001-02-20
ZA991946B (en) 1999-09-13
JP2000186090A (ja) 2000-07-04
EP0941994B1 (en) 2003-05-14
CA2265095A1 (en) 1999-09-11
HU9900589D0 (en) 1999-05-28
TR199900531A2 (tr) 1999-10-21
CN1236780A (zh) 1999-12-01
PE20000337A1 (es) 2000-05-13
NO991150D0 (no) 1999-03-10
HRP990077B1 (en) 2003-08-31
IL128869A0 (en) 2000-01-31
MA26612A1 (fr) 2004-12-20
HK1023343A1 (en) 2000-09-08
HUP9900589A1 (hu) 2000-03-28
AR016453A1 (es) 2001-07-04
CZ291514B6 (cs) 2003-03-12
IL128869A (en) 2003-09-17
RU2218340C2 (ru) 2003-12-10
NO312297B1 (no) 2002-04-22
HRP990077A2 (en) 2000-02-29
SI0941994T1 (en) 2003-10-31
NO991150L (no) 1999-09-13
CA2265095C (en) 2008-07-22
PT941994E (pt) 2003-09-30
PL331875A1 (en) 1999-09-13
ID23575A (id) 2000-05-04
KR19990077741A (ko) 1999-10-25
ATE240332T1 (de) 2003-05-15
EP0941994A1 (en) 1999-09-15
AU752408B2 (en) 2002-09-19
NZ334526A (en) 2000-07-28
UY25419A1 (es) 2001-11-30
BR9901095A (pt) 2000-05-02
YU12099A (sh) 2000-10-30
DE69907784D1 (de) 2003-06-18
US6194410B1 (en) 2001-02-27
TW585865B (en) 2004-05-01
CN1118468C (zh) 2003-08-20
JP3231288B2 (ja) 2001-11-19
MY119536A (en) 2005-06-30
CZ82599A3 (cs) 1999-09-15
AU2038399A (en) 1999-09-23
DK0941994T3 (da) 2003-09-08
KR100313181B1 (ko) 2001-11-05

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