MXPA03002923A - Inhibidores de proteasas serina de peso molecular inferior que poseen radicales polihidroxialquilo y polihidroxicicloalquilo. - Google Patents

Inhibidores de proteasas serina de peso molecular inferior que poseen radicales polihidroxialquilo y polihidroxicicloalquilo.

Info

Publication number
MXPA03002923A
MXPA03002923A MXPA03002923A MXPA03002923A MXPA03002923A MX PA03002923 A MXPA03002923 A MX PA03002923A MX PA03002923 A MXPA03002923 A MX PA03002923A MX PA03002923 A MXPA03002923 A MX PA03002923A MX PA03002923 A MXPA03002923 A MX PA03002923A
Authority
MX
Mexico
Prior art keywords
polyhydroxy
alkyl
low molecular
protease inhibitors
serine protease
Prior art date
Application number
MXPA03002923A
Other languages
English (en)
Inventor
Dieter Herr
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of MXPA03002923A publication Critical patent/MXPA03002923A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MXPA03002923A 2000-10-06 2001-09-27 Inhibidores de proteasas serina de peso molecular inferior que poseen radicales polihidroxialquilo y polihidroxicicloalquilo. MXPA03002923A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10049937A DE10049937A1 (de) 2000-10-06 2000-10-06 Niedermolekulare Inhibitoren von Serinproteasen mit Polyhydroxyalkyl- und Polyhydroxycycloalkylresten
PCT/EP2001/011207 WO2002030940A2 (de) 2000-10-06 2001-09-27 Niedermolekulare inhibitoren von serinproteasen mit polyhydroxyalkyl- und polyhydroxycycloakylresten

Publications (1)

Publication Number Publication Date
MXPA03002923A true MXPA03002923A (es) 2003-08-07

Family

ID=7659136

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03002923A MXPA03002923A (es) 2000-10-06 2001-09-27 Inhibidores de proteasas serina de peso molecular inferior que poseen radicales polihidroxialquilo y polihidroxicicloalquilo.

Country Status (9)

Country Link
US (3) US20040048815A1 (es)
EP (1) EP1370573A2 (es)
JP (1) JP2004511489A (es)
AR (1) AR036326A1 (es)
AU (1) AU2001289932A1 (es)
CA (1) CA2424926A1 (es)
DE (1) DE10049937A1 (es)
MX (1) MXPA03002923A (es)
WO (1) WO2002030940A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
EP3852820A4 (en) * 2018-09-17 2022-06-15 Board of Regents, The University of Texas System COMPOSITIONS AND METHODS FOR TREATMENT OF BONE INJURIES

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4115468A1 (de) * 1991-05-11 1992-11-12 Behringwerke Ag Amidinophenylalaninderivate, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel als antikoagulantien
DE4206858A1 (de) * 1992-03-05 1993-09-09 Behringwerke Ag Glycopeptid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
US5705487A (en) * 1994-03-04 1998-01-06 Eli Lilly And Company Antithrombotic agents
DE4421052A1 (de) * 1994-06-17 1995-12-21 Basf Ag Neue Thrombininhibitoren, ihre Herstellung und Verwendung
DE4443390A1 (de) * 1994-12-06 1996-06-13 Basf Ag Neue dipeptidische p-Amidinobenzylamide mit N-terminalen Sulfonyl- bzw. Aminosulfonylresten
US5932567A (en) * 1995-02-10 1999-08-03 Basf Aktiengesellschaft Thrombin inhibitors
WO1996025426A1 (de) * 1995-02-17 1996-08-22 Basf Aktiengesellschaft Neue dipeptidische amidine als thrombin-inhibitoren
US6239150B1 (en) * 1995-07-26 2001-05-29 Mitsubishi Chemical Corporation Penicillaminamide derivatives
DE19632772A1 (de) * 1996-08-14 1998-02-19 Basf Ag Neue Benzamidine
DE19632773A1 (de) * 1996-08-14 1998-02-19 Basf Ag Neue Thrombininhibitoren
US6486129B1 (en) * 1998-06-17 2002-11-26 Akzo Nobel N.V. Antithrombotic compounds
KR20000047461A (ko) * 1998-12-29 2000-07-25 성재갑 트롬빈 억제제

Also Published As

Publication number Publication date
EP1370573A2 (de) 2003-12-17
DE10049937A1 (de) 2002-04-11
WO2002030940A2 (de) 2002-04-18
WO2002030940A3 (de) 2003-10-02
CA2424926A1 (en) 2003-04-04
US20110071285A1 (en) 2011-03-24
US20040048815A1 (en) 2004-03-11
US20120190832A1 (en) 2012-07-26
JP2004511489A (ja) 2004-04-15
AR036326A1 (es) 2004-09-01
AU2001289932A1 (en) 2002-04-22

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