DK1011329T3 - 7-Methylthiooxomethyl- og 7-methylthiodioxomethyl-paclitaxeler - Google Patents

7-Methylthiooxomethyl- og 7-methylthiodioxomethyl-paclitaxeler

Info

Publication number
DK1011329T3
DK1011329T3 DK98908734T DK98908734T DK1011329T3 DK 1011329 T3 DK1011329 T3 DK 1011329T3 DK 98908734 T DK98908734 T DK 98908734T DK 98908734 T DK98908734 T DK 98908734T DK 1011329 T3 DK1011329 T3 DK 1011329T3
Authority
DK
Denmark
Prior art keywords
methylthiooxomethyl
methylthiodioxomethyl
paclitaxels
present
invention concerns
Prior art date
Application number
DK98908734T
Other languages
English (en)
Inventor
Jerzy Golik
Dolatrai M Vyas
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DK1011329T3 publication Critical patent/DK1011329T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
DK98908734T 1997-02-28 1998-02-24 7-Methylthiooxomethyl- og 7-methylthiodioxomethyl-paclitaxeler DK1011329T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3948097P 1997-02-28 1997-02-28
PCT/US1998/003741 WO1998037765A1 (en) 1997-02-28 1998-02-24 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels

Publications (1)

Publication Number Publication Date
DK1011329T3 true DK1011329T3 (da) 2003-12-22

Family

ID=21905699

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98908734T DK1011329T3 (da) 1997-02-28 1998-02-24 7-Methylthiooxomethyl- og 7-methylthiodioxomethyl-paclitaxeler

Country Status (11)

Country Link
US (1) US5902822A (da)
EP (1) EP1011329B1 (da)
JP (1) JP2001513778A (da)
AT (1) ATE250340T1 (da)
AU (1) AU724591B2 (da)
CA (1) CA2282264A1 (da)
DE (1) DE69818492T2 (da)
DK (1) DK1011329T3 (da)
ES (1) ES2207817T3 (da)
PT (1) PT1011329E (da)
WO (1) WO1998037765A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046904A1 (en) * 1998-03-12 1999-09-16 John Griffits Improved realtime internet functions by use of a hybrid pstn and ip protocol means
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
DE60131537T2 (de) 2000-06-22 2008-10-23 Nitromed, Inc., Lexington Nitrosierte und nitrosylierte taxane, zubereitungen und methoden der verwendung
PL217731B1 (pl) 2006-06-01 2014-08-29 Tomasz Byrski Sposób wykrywania genetycznie uwarunkowanej obniżonej odpowiedzi na chemioterapię cytostatykiem taksanowym, zastosowanie mutacji założycielskiej oraz zestawu do wykrywania takiej odpowiedzi
KR20160018534A (ko) 2013-06-11 2016-02-17 바이엘 파마 악티엔게젤샤프트 Mps-1 키나제 억제제 및 유사분열 억제제를 포함하는 암의 치료를 위한 조합물

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US4960790A (en) * 1989-03-09 1990-10-02 University Of Kansas Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
UA39860C2 (uk) * 1991-09-23 2001-07-16 Флоріда Стейт Юніверсіті 10-дезацетокситаксол та його похідні
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
ATE181551T1 (de) * 1992-04-17 1999-07-15 Abbott Lab Taxol-derivate
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
US5294637A (en) * 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
CA2100808A1 (en) * 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
FR2697019B1 (fr) * 1992-10-15 1994-11-25 Rhone Poulenc Rorer Sa Nouveaux dérivés du taxane, leur préparation et les compositions pharmaceutiques qui les contiennent.
CA2109861C (en) * 1992-12-04 1999-03-16 Shu-Hui Chen 6,7-modified paclitaxels
EP1251127B1 (en) * 1992-12-23 2005-11-09 Bristol-Myers Squibb Company Novel sidechain-bearing taxanes and intermediates thereof
MX9308012A (es) * 1992-12-24 1994-08-31 Bristol Myers Squibb Co Eteres fosfonooximetilicos de derivados de taxano, solubles en agua y composiciones farmaceuticas que los incluyen.
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
CA2157114C (en) * 1993-03-05 2003-12-16 Robert A. Holton Process for the preparation of 9-desoxotaxanes
US5703247A (en) * 1993-03-11 1997-12-30 Virginia Tech Intellectual Properties, Inc. 2-Debenzoyl-2-acyl taxol derivatives and methods for making same
IL112412A (en) * 1994-01-28 2000-02-29 Upjohn Co Delta 12,13-iso-taxol analogs and antineoplastic pharmaceutical compositions containing them
EP0764643A1 (en) * 1994-06-09 1997-03-26 Daiichi Pharmaceutical Co., Ltd. Deacetoxytaxol derivative
NZ288802A (en) * 1994-06-28 1998-05-27 Upjohn Co Ether taxol derivatives, preparation and pharmaceutical compositions thereof
KR100220490B1 (ko) * 1994-07-26 1999-09-15 다리오 보나꼬르시 항암작용을 갖는 반합성 탁산유도체
US6201140B1 (en) * 1994-07-28 2001-03-13 Bristol-Myers Squibb Company 7-0-ethers of taxane derivatives

Also Published As

Publication number Publication date
AU6668698A (en) 1998-09-18
AU724591B2 (en) 2000-09-28
US5902822A (en) 1999-05-11
WO1998037765A1 (en) 1998-09-03
EP1011329A1 (en) 2000-06-28
CA2282264A1 (en) 1998-09-03
EP1011329A4 (en) 2000-07-26
EP1011329B1 (en) 2003-09-24
DE69818492T2 (de) 2004-07-22
PT1011329E (pt) 2004-01-30
ATE250340T1 (de) 2003-10-15
ES2207817T3 (es) 2004-06-01
JP2001513778A (ja) 2001-09-04
DE69818492D1 (en) 2003-10-30

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