DK0971717T3 - Cytotoksiske aminosukker- og relaterede sukkerderivater af indolopyrrolocarbazoler - Google Patents
Cytotoksiske aminosukker- og relaterede sukkerderivater af indolopyrrolocarbazolerInfo
- Publication number
- DK0971717T3 DK0971717T3 DK97939482T DK97939482T DK0971717T3 DK 0971717 T3 DK0971717 T3 DK 0971717T3 DK 97939482 T DK97939482 T DK 97939482T DK 97939482 T DK97939482 T DK 97939482T DK 0971717 T3 DK0971717 T3 DK 0971717T3
- Authority
- DK
- Denmark
- Prior art keywords
- sugar
- indolopyrrolocarbazoles
- derivatives
- cytotoxic amino
- sugar derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2465796P | 1996-08-22 | 1996-08-22 | |
PCT/US1997/014738 WO1998007433A1 (en) | 1996-08-22 | 1997-08-21 | Cytotoxic amino sugar and related sugar derivatives of indolopyrrolocarbazoles |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0971717T3 true DK0971717T3 (da) | 2002-03-25 |
Family
ID=21821733
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK97939482T DK0971717T3 (da) | 1996-08-22 | 1997-08-21 | Cytotoksiske aminosukker- og relaterede sukkerderivater af indolopyrrolocarbazoler |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0971717B1 (da) |
JP (1) | JP2000516250A (da) |
KR (1) | KR100450034B1 (da) |
CN (1) | CN1097460C (da) |
AT (1) | ATE210988T1 (da) |
AU (1) | AU710669B2 (da) |
BR (1) | BR9711306A (da) |
CY (1) | CY2261B1 (da) |
DE (1) | DE69709407T2 (da) |
DK (1) | DK0971717T3 (da) |
ES (1) | ES2169414T3 (da) |
HK (1) | HK1024177A1 (da) |
HU (1) | HUP9903931A3 (da) |
IL (1) | IL127918A0 (da) |
NO (1) | NO312071B1 (da) |
NZ (1) | NZ333536A (da) |
PL (1) | PL187205B1 (da) |
PT (1) | PT971717E (da) |
RU (1) | RU2167880C2 (da) |
WO (1) | WO1998007433A1 (da) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5922860A (en) * | 1994-05-09 | 1999-07-13 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazole derivatives |
US6127401A (en) * | 1998-06-05 | 2000-10-03 | Cephalon, Inc. | Bridged indenopyrrolocarbazoles |
US6833373B1 (en) | 1998-12-23 | 2004-12-21 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
US6841567B1 (en) | 1999-02-12 | 2005-01-11 | Cephalon, Inc. | Cyclic substituted fused pyrrolocarbazoles and isoindolones |
US6399780B1 (en) | 1999-08-20 | 2002-06-04 | Cephalon, Inc. | Isomeric fused pyrrolocarbazoles and isoindolones |
US7122679B2 (en) * | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
US6630500B2 (en) | 2000-08-25 | 2003-10-07 | Cephalon, Inc. | Selected fused pyrrolocarbazoles |
US6610727B2 (en) | 2000-10-06 | 2003-08-26 | Bristol-Myers Squibb Company | Anhydro sugar derivatives of indolocarbazoles |
US6677450B2 (en) | 2000-10-06 | 2004-01-13 | Bristol-Myers Squibb Company | Topoisomerase inhibitors |
US6653290B2 (en) * | 2000-10-06 | 2003-11-25 | Bristol-Myers Squibb Company | Tumor proliferation inhibitors |
US6555677B2 (en) | 2000-10-31 | 2003-04-29 | Merck & Co., Inc. | Phase transfer catalyzed glycosidation of an indolocarbazole |
WO2002077255A1 (en) * | 2001-03-22 | 2002-10-03 | Bristol-Myers Squibb Company | Topoisomerase i selective cytotoxic sugar derivatives of indolopyrrolocarbazoles |
AU2003248104A1 (en) * | 2003-07-24 | 2005-02-14 | Banyu Pharmaceutical Co., Ltd. | Crystalline 6-n-pyridylmethylaminoindolocarbazoles |
AU2003248103A1 (en) * | 2003-07-24 | 2005-02-14 | Banyu Pharmaceutical Co., Ltd | Indolopyrrolocarbazole derivative and antitumor agent |
US7241779B2 (en) | 2003-12-23 | 2007-07-10 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US7169802B2 (en) | 2003-12-23 | 2007-01-30 | Cephalon, Inc. | Fused pyrrolocarbazoles |
DE102004025726B4 (de) | 2004-05-26 | 2006-07-06 | Roder, Hanno, Dr. | Verwendung eines spezifischen K252a-Derivats zur Verhinderung oder Behandlung der Alzheimerschen Krankheit |
WO2008076394A1 (en) * | 2006-12-14 | 2008-06-26 | Tautatis, Inc. | Compositions and methods for the treatment of cancer |
ES2326459B1 (es) | 2008-04-08 | 2010-05-28 | Universidad De Oviedo | Indolocarbazoles glicosilados, su procedimiento de obtencion y sus usos. |
NZ592868A (en) | 2008-11-19 | 2012-08-31 | Cephalon Inc | Novel forms of an indazolo [5,4-a] pyrrolo [3,4-c] carbazole compound |
RU2557554C1 (ru) * | 2014-09-09 | 2015-07-27 | Федеральное государственное бюджетное учреждение "Российский онкологический научный центр имени Н.Н. Блохина" Российской академии медицинских наук (ФГБУ "РОНЦ им. Н.Н. Блохина" РАМН) | Производные индолокарбазолов, блокирующие васкулогенную мимикрию в опухоли |
CN105198785B (zh) * | 2015-09-29 | 2018-08-21 | 浙江工业大学 | 一种顺丁烯二酰亚胺类化合物及其制备与应用 |
US11319320B2 (en) | 2017-11-06 | 2022-05-03 | Snap Bio, Inc. | PIM kinase inhibitor compositions, methods, and uses thereof |
CN109970822B (zh) * | 2017-12-27 | 2023-03-28 | 上海科胜药物研发有限公司 | 一种合成埃格列净中间体的制备方法 |
CN112457235B (zh) * | 2020-12-02 | 2023-04-25 | 烟台凯博医药科技有限公司 | 一种7-甲基吲哚的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL97233A (en) * | 1990-03-06 | 1995-03-30 | Bristol Myers Squibb Co | Analogs of rabamycin, their manufacture and pharmaceutical preparations containing them |
NZ245203A (en) * | 1991-11-29 | 1997-07-27 | Banyu Pharma Co Ltd | 5h-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h)-dione derivatives substituted in position-13 by a pentose or hexose group; corresponding indolo-furano(anhydride)intermediates |
WO1996004293A1 (fr) * | 1994-08-02 | 1996-02-15 | Banyu Pharmaceutical Co., Ltd. | Indolopyrrolocarbazoles antitumoraux |
-
1997
- 1997-08-21 BR BR9711306A patent/BR9711306A/pt not_active Application Discontinuation
- 1997-08-21 IL IL12791897A patent/IL127918A0/xx unknown
- 1997-08-21 NZ NZ333536A patent/NZ333536A/en unknown
- 1997-08-21 AT AT97939482T patent/ATE210988T1/de not_active IP Right Cessation
- 1997-08-21 RU RU99105751/04A patent/RU2167880C2/ru not_active IP Right Cessation
- 1997-08-21 PL PL97331709A patent/PL187205B1/pl not_active IP Right Cessation
- 1997-08-21 JP JP10510975A patent/JP2000516250A/ja not_active Ceased
- 1997-08-21 EP EP97939482A patent/EP0971717B1/en not_active Expired - Lifetime
- 1997-08-21 PT PT97939482T patent/PT971717E/pt unknown
- 1997-08-21 HU HU9903931A patent/HUP9903931A3/hu unknown
- 1997-08-21 KR KR10-1999-7001358A patent/KR100450034B1/ko not_active IP Right Cessation
- 1997-08-21 DE DE69709407T patent/DE69709407T2/de not_active Expired - Fee Related
- 1997-08-21 ES ES97939482T patent/ES2169414T3/es not_active Expired - Lifetime
- 1997-08-21 CN CN97197437A patent/CN1097460C/zh not_active Expired - Fee Related
- 1997-08-21 WO PCT/US1997/014738 patent/WO1998007433A1/en not_active Application Discontinuation
- 1997-08-21 DK DK97939482T patent/DK0971717T3/da active
- 1997-08-21 AU AU41558/97A patent/AU710669B2/en not_active Ceased
-
1999
- 1999-02-19 NO NO19990789A patent/NO312071B1/no unknown
-
2000
- 2000-06-13 HK HK00103550A patent/HK1024177A1/xx not_active IP Right Cessation
-
2002
- 2002-03-04 CY CY0200011A patent/CY2261B1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO1998007433A1 (en) | 1998-02-26 |
IL127918A0 (en) | 1999-11-30 |
AU710669B2 (en) | 1999-09-23 |
PL331709A1 (en) | 1999-08-02 |
PL187205B1 (pl) | 2004-06-30 |
EP0971717A1 (en) | 2000-01-19 |
DE69709407D1 (de) | 2002-01-31 |
HUP9903931A3 (en) | 2000-09-28 |
NO312071B1 (no) | 2002-03-11 |
EP0971717A4 (en) | 2000-04-12 |
BR9711306A (pt) | 1999-08-17 |
KR20000068225A (ko) | 2000-11-25 |
KR100450034B1 (ko) | 2004-09-24 |
DE69709407T2 (de) | 2002-05-29 |
JP2000516250A (ja) | 2000-12-05 |
NO990789D0 (no) | 1999-02-19 |
NZ333536A (en) | 1999-10-28 |
CN1228704A (zh) | 1999-09-15 |
HUP9903931A2 (hu) | 2000-03-28 |
ATE210988T1 (de) | 2002-01-15 |
AU4155897A (en) | 1998-03-06 |
ES2169414T3 (es) | 2002-07-01 |
HK1024177A1 (en) | 2000-10-05 |
CN1097460C (zh) | 2003-01-01 |
PT971717E (pt) | 2002-06-28 |
EP0971717B1 (en) | 2001-12-19 |
CY2261B1 (en) | 2003-07-04 |
NO990789L (no) | 1999-02-19 |
RU2167880C2 (ru) | 2001-05-27 |
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