HK1030218A1 - Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and compositions containing same. - Google Patents

Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and compositions containing same.

Info

Publication number
HK1030218A1
HK1030218A1 HK01101230A HK01101230A HK1030218A1 HK 1030218 A1 HK1030218 A1 HK 1030218A1 HK 01101230 A HK01101230 A HK 01101230A HK 01101230 A HK01101230 A HK 01101230A HK 1030218 A1 HK1030218 A1 HK 1030218A1
Authority
HK
Hong Kong
Prior art keywords
iminomethyl
medicines
amino
preparation
application
Prior art date
Application number
HK01101230A
Inventor
Jeremiah Harnett
Dennis Bigg
De Lassauniere Pierre Chabrier
Serge Auvin
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of HK1030218A1 publication Critical patent/HK1030218A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D521/00—Heterocyclic compounds containing unspecified hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

The invention concerns novel 2-(iminomethyl)amino-phenyl derivatives, their preparation, their application as medicines and compositions containing them.
HK01101230A 1997-06-20 2001-02-21 Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and compositions containing same. HK1030218A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9707701A FR2764889B1 (en) 1997-06-20 1997-06-20 NOVEL 2- (IMINOMETHYL) AMINO-PHENYL DERIVATIVES, THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
PCT/FR1998/001250 WO1998058934A1 (en) 1997-06-20 1998-06-15 Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and compositions containing same

Publications (1)

Publication Number Publication Date
HK1030218A1 true HK1030218A1 (en) 2001-04-27

Family

ID=9508226

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01101230A HK1030218A1 (en) 1997-06-20 2001-02-21 Novel 2-(iminomethyl)amino-phenyl derivatives, preparation, application as medicines and compositions containing same.

Country Status (29)

Country Link
EP (1) EP0991654B1 (en)
JP (1) JP2002507965A (en)
KR (2) KR100545946B1 (en)
CN (1) CN1195762C (en)
AR (1) AR012250A1 (en)
AT (1) ATE297935T1 (en)
AU (1) AU737964B2 (en)
BR (1) BR9810197B1 (en)
CA (1) CA2294809C (en)
CZ (1) CZ299237B6 (en)
DE (1) DE69830584T2 (en)
DK (1) DK0991654T3 (en)
ES (1) ES2244068T3 (en)
FR (1) FR2764889B1 (en)
HK (1) HK1030218A1 (en)
HU (1) HUP0002425A3 (en)
IL (1) IL133223A (en)
MY (1) MY123193A (en)
NO (1) NO315321B1 (en)
NZ (1) NZ501656A (en)
PL (1) PL191987B1 (en)
PT (1) PT991654E (en)
RU (1) RU2202543C2 (en)
SK (1) SK286911B6 (en)
TR (1) TR199903175T2 (en)
TW (1) TW422842B (en)
UA (1) UA70921C2 (en)
WO (1) WO1998058934A1 (en)
ZA (1) ZA985392B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801990D0 (en) 1998-06-04 1998-06-04 Astra Ab New 3-aryl propionic acid derivatives and analogs
AR019190A1 (en) * 1998-07-08 2001-12-26 Sod Conseils Rech Applic DERIVATIVES OF 2-AMINOPIRIDINES, INTERMEDIATE PRODUCTS FOR THEIR PREPARATION, DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE TO PREPARE DRUGS
WO2000008018A1 (en) * 1998-08-07 2000-02-17 Takeda Chemical Industries, Ltd. Benzothiepin derivatives, process for the preparation of the same and uses thereof
FR2783519B1 (en) * 1998-09-23 2003-01-24 Sod Conseils Rech Applic NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2798127A1 (en) * 1999-09-03 2001-03-09 Expansia Sa NOVEL PROCESS FOR THE PREPARATION OF AMIDINES DERIVED FROM 6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMMANE-2-CARBOXYLIC ACID
FR2812546B1 (en) * 2000-08-01 2008-11-21 Sod Conseils Rech Applic 5-CHAIN HETEROCYCLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
TWI283577B (en) * 1999-10-11 2007-07-11 Sod Conseils Rech Applic Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof
FR2799461B1 (en) * 1999-10-11 2002-01-04 Sod Conseils Rech Applic 5-CHAIN CHAIN HETEROCYCLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
RU2380362C2 (en) * 1999-10-11 2010-01-27 Сосьете Де Консей Де Решерш З Derivatives of five-member heterocycles, method of production and use thereof as medicinal agents
FR2801053B1 (en) * 1999-11-16 2004-06-25 Sod Conseils Rech Applic NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
SE9904677D0 (en) * 1999-12-20 1999-12-20 Astra Ab Novel compounds
SE9904676D0 (en) * 1999-12-20 1999-12-20 Astra Ab Novel compounds
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
AU2001282829A1 (en) * 2000-09-05 2002-03-22 Astrazeneca Ab Amidine derivatives which are inhibitors of nitric oxide synthase
TWI248438B (en) * 2001-04-10 2006-02-01 Sod Conseils Rech Applic Derivatives of heterocycles with 5 members, their preparation and their use as medicaments
CA2450589C (en) 2001-06-08 2011-12-20 Cytokine Pharmasciences, Inc. Isoxazoline compounds having mif antagonist activity
HU228783B1 (en) * 2001-07-26 2013-05-28 Greenearth Cleaning Dry cleaning apparatus and method capable of utilizing a siloxane solvent
DE10233817A1 (en) * 2002-07-25 2004-02-12 Aventis Pharma Deutschland Gmbh Substituted diaryl heterocycles, process for their preparation and their use as medicaments
FR2842808B1 (en) 2002-07-25 2004-09-10 Sod Conseils Rech Applic NOVEL ARYLIMIDAZOLA DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS
US7141561B2 (en) 2002-07-25 2006-11-28 Sanofi-Aventis Deutschland Gmbh Substituted diaryl heterocycles, process for their preparation and their use as medicaments
CN101098697B (en) * 2004-03-26 2010-11-10 塞托凯恩药物科学公司 Compounds, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
WO2006022442A1 (en) * 2004-08-24 2006-03-02 Santen Pharmaceutical Co., Ltd. Novel heterocyclic amide derivatives having dihydroorotate dehydrogenase inhibiting activity
AU2006222556B2 (en) * 2005-03-11 2011-09-29 Armaron Bio Pty Ltd Flavonoid compounds and uses thereof
CN102740699A (en) 2009-09-04 2012-10-17 范德比尔特大学 Mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
US9051296B2 (en) 2009-11-16 2015-06-09 Raqualia Pharma Inc. Aryl carboxamide derivatives as TTX-S blockers
CN104662011B (en) * 2012-07-12 2017-09-29 康尊知识产权公司 Treat the chroman derivative of mitochondrial disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9127376D0 (en) * 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
CZ29996A3 (en) * 1993-08-12 1996-09-11 Astra Ab Amidine derivatives with activities of nitrogen oxide sythetase
DE69511260T2 (en) * 1994-05-07 2000-03-16 Astra Ab BICYCLIC AMIDINE DERIVATIVES AS NO-SYNTHETASE INHIBITORS

Also Published As

Publication number Publication date
CZ299237B6 (en) 2008-05-28
NO996208L (en) 2000-02-15
FR2764889A1 (en) 1998-12-24
MY123193A (en) 2006-05-31
IL133223A (en) 2004-09-27
AU737964B2 (en) 2001-09-06
SK179699A3 (en) 2000-05-16
ATE297935T1 (en) 2005-07-15
EP0991654B1 (en) 2005-06-15
DK0991654T3 (en) 2005-10-17
BR9810197A (en) 2000-08-08
CA2294809C (en) 2010-02-02
NZ501656A (en) 2001-12-21
PT991654E (en) 2005-10-31
FR2764889B1 (en) 2000-09-01
AU8218998A (en) 1999-01-04
IL133223A0 (en) 2001-03-19
NO315321B1 (en) 2003-08-18
CA2294809A1 (en) 1998-12-30
AR012250A1 (en) 2000-09-27
TW422842B (en) 2001-02-21
EP0991654A1 (en) 2000-04-12
KR20010013983A (en) 2001-02-26
DE69830584T2 (en) 2006-03-16
HUP0002425A3 (en) 2001-12-28
UA70921C2 (en) 2004-11-15
RU2202543C2 (en) 2003-04-20
JP2002507965A (en) 2002-03-12
BR9810197B1 (en) 2010-02-09
SK286911B6 (en) 2009-07-06
NO996208D0 (en) 1999-12-15
PL337499A1 (en) 2000-08-28
KR100618478B1 (en) 2006-09-01
CN1264385A (en) 2000-08-23
CZ459799A3 (en) 2000-07-12
TR199903175T2 (en) 2000-04-21
WO1998058934A1 (en) 1998-12-30
HUP0002425A1 (en) 2001-11-28
PL191987B1 (en) 2006-07-31
ES2244068T3 (en) 2005-12-01
DE69830584D1 (en) 2005-07-21
CN1195762C (en) 2005-04-06
KR20050098970A (en) 2005-10-12
ZA985392B (en) 1999-01-20
KR100545946B1 (en) 2006-01-26

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20140615