CY2261B1 - Cytotoxic amino sugar and relatd sugar derivativesof indolopyrrolocarbazoles - Google Patents

Cytotoxic amino sugar and relatd sugar derivativesof indolopyrrolocarbazoles

Info

Publication number
CY2261B1
CY2261B1 CY0200011A CY0200011A CY2261B1 CY 2261 B1 CY2261 B1 CY 2261B1 CY 0200011 A CY0200011 A CY 0200011A CY 0200011 A CY0200011 A CY 0200011A CY 2261 B1 CY2261 B1 CY 2261B1
Authority
CY
Cyprus
Prior art keywords
sugar
indolopyrrolocarbazoles
relatd
derivativesof
cytotoxic amino
Prior art date
Application number
CY0200011A
Other languages
English (en)
Inventor
Mark George Saulnier
Neelakantan Balasubramanian
David Bertil Frennesson
Laurent Denis R St
David R Langley
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CY2261B1 publication Critical patent/CY2261B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials
CY0200011A 1996-08-22 2002-03-04 Cytotoxic amino sugar and relatd sugar derivativesof indolopyrrolocarbazoles CY2261B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2465796P 1996-08-22 1996-08-22

Publications (1)

Publication Number Publication Date
CY2261B1 true CY2261B1 (en) 2003-07-04

Family

ID=21821733

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0200011A CY2261B1 (en) 1996-08-22 2002-03-04 Cytotoxic amino sugar and relatd sugar derivativesof indolopyrrolocarbazoles

Country Status (20)

Country Link
EP (1) EP0971717B1 (xx)
JP (1) JP2000516250A (xx)
KR (1) KR100450034B1 (xx)
CN (1) CN1097460C (xx)
AT (1) ATE210988T1 (xx)
AU (1) AU710669B2 (xx)
BR (1) BR9711306A (xx)
CY (1) CY2261B1 (xx)
DE (1) DE69709407T2 (xx)
DK (1) DK0971717T3 (xx)
ES (1) ES2169414T3 (xx)
HK (1) HK1024177A1 (xx)
HU (1) HUP9903931A3 (xx)
IL (1) IL127918A0 (xx)
NO (1) NO312071B1 (xx)
NZ (1) NZ333536A (xx)
PL (1) PL187205B1 (xx)
PT (1) PT971717E (xx)
RU (1) RU2167880C2 (xx)
WO (1) WO1998007433A1 (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922860A (en) * 1994-05-09 1999-07-13 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
US6127401A (en) * 1998-06-05 2000-10-03 Cephalon, Inc. Bridged indenopyrrolocarbazoles
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6841567B1 (en) 1999-02-12 2005-01-11 Cephalon, Inc. Cyclic substituted fused pyrrolocarbazoles and isoindolones
US6399780B1 (en) 1999-08-20 2002-06-04 Cephalon, Inc. Isomeric fused pyrrolocarbazoles and isoindolones
US7122679B2 (en) * 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
US6630500B2 (en) 2000-08-25 2003-10-07 Cephalon, Inc. Selected fused pyrrolocarbazoles
US6610727B2 (en) 2000-10-06 2003-08-26 Bristol-Myers Squibb Company Anhydro sugar derivatives of indolocarbazoles
US6677450B2 (en) 2000-10-06 2004-01-13 Bristol-Myers Squibb Company Topoisomerase inhibitors
US6653290B2 (en) * 2000-10-06 2003-11-25 Bristol-Myers Squibb Company Tumor proliferation inhibitors
US6555677B2 (en) 2000-10-31 2003-04-29 Merck & Co., Inc. Phase transfer catalyzed glycosidation of an indolocarbazole
WO2002077255A1 (en) * 2001-03-22 2002-10-03 Bristol-Myers Squibb Company Topoisomerase i selective cytotoxic sugar derivatives of indolopyrrolocarbazoles
AU2003248104A1 (en) * 2003-07-24 2005-02-14 Banyu Pharmaceutical Co., Ltd. Crystalline 6-n-pyridylmethylaminoindolocarbazoles
AU2003248103A1 (en) * 2003-07-24 2005-02-14 Banyu Pharmaceutical Co., Ltd Indolopyrrolocarbazole derivative and antitumor agent
US7241779B2 (en) 2003-12-23 2007-07-10 Cephalon, Inc. Fused pyrrolocarbazoles
US7169802B2 (en) 2003-12-23 2007-01-30 Cephalon, Inc. Fused pyrrolocarbazoles
DE102004025726B4 (de) 2004-05-26 2006-07-06 Roder, Hanno, Dr. Verwendung eines spezifischen K252a-Derivats zur Verhinderung oder Behandlung der Alzheimerschen Krankheit
WO2008076394A1 (en) * 2006-12-14 2008-06-26 Tautatis, Inc. Compositions and methods for the treatment of cancer
ES2326459B1 (es) 2008-04-08 2010-05-28 Universidad De Oviedo Indolocarbazoles glicosilados, su procedimiento de obtencion y sus usos.
NZ592868A (en) 2008-11-19 2012-08-31 Cephalon Inc Novel forms of an indazolo [5,4-a] pyrrolo [3,4-c] carbazole compound
RU2557554C1 (ru) * 2014-09-09 2015-07-27 Федеральное государственное бюджетное учреждение "Российский онкологический научный центр имени Н.Н. Блохина" Российской академии медицинских наук (ФГБУ "РОНЦ им. Н.Н. Блохина" РАМН) Производные индолокарбазолов, блокирующие васкулогенную мимикрию в опухоли
CN105198785B (zh) * 2015-09-29 2018-08-21 浙江工业大学 一种顺丁烯二酰亚胺类化合物及其制备与应用
US11319320B2 (en) 2017-11-06 2022-05-03 Snap Bio, Inc. PIM kinase inhibitor compositions, methods, and uses thereof
CN109970822B (zh) * 2017-12-27 2023-03-28 上海科胜药物研发有限公司 一种合成埃格列净中间体的制备方法
CN112457235B (zh) * 2020-12-02 2023-04-25 烟台凯博医药科技有限公司 一种7-甲基吲哚的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL97233A (en) * 1990-03-06 1995-03-30 Bristol Myers Squibb Co Analogs of rabamycin, their manufacture and pharmaceutical preparations containing them
NZ245203A (en) * 1991-11-29 1997-07-27 Banyu Pharma Co Ltd 5h-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6h)-dione derivatives substituted in position-13 by a pentose or hexose group; corresponding indolo-furano(anhydride)intermediates
WO1996004293A1 (fr) * 1994-08-02 1996-02-15 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazoles antitumoraux

Also Published As

Publication number Publication date
WO1998007433A1 (en) 1998-02-26
IL127918A0 (en) 1999-11-30
AU710669B2 (en) 1999-09-23
PL331709A1 (en) 1999-08-02
PL187205B1 (pl) 2004-06-30
EP0971717A1 (en) 2000-01-19
DE69709407D1 (de) 2002-01-31
HUP9903931A3 (en) 2000-09-28
NO312071B1 (no) 2002-03-11
EP0971717A4 (en) 2000-04-12
BR9711306A (pt) 1999-08-17
KR20000068225A (ko) 2000-11-25
KR100450034B1 (ko) 2004-09-24
DE69709407T2 (de) 2002-05-29
JP2000516250A (ja) 2000-12-05
NO990789D0 (no) 1999-02-19
NZ333536A (en) 1999-10-28
CN1228704A (zh) 1999-09-15
HUP9903931A2 (hu) 2000-03-28
ATE210988T1 (de) 2002-01-15
AU4155897A (en) 1998-03-06
ES2169414T3 (es) 2002-07-01
HK1024177A1 (en) 2000-10-05
CN1097460C (zh) 2003-01-01
PT971717E (pt) 2002-06-28
EP0971717B1 (en) 2001-12-19
DK0971717T3 (da) 2002-03-25
NO990789L (no) 1999-02-19
RU2167880C2 (ru) 2001-05-27

Similar Documents

Publication Publication Date Title
CY2261B1 (en) Cytotoxic amino sugar and relatd sugar derivativesof indolopyrrolocarbazoles
EP0960107A4 (xx)
UA39158C2 (uk) Похідні n4-оксикарбоніл-5'-дезокси-5-фторцитидину та фармацевтичний препарат на їх основі
DE69905170D1 (en) Thiazolopyrimidinderivate
AU5186799A (en) Peptides of il-2 and derivatives thereof and their use as therapeutic agents
MX9601994A (es) Profarmacos de derivados de paclitaxel.
CA2152771A1 (en) 7-o-ethers of taxane derivatives
AU5892399A (en) 1, 2, 4-triazole-3-thione compounds
ZA9610460B (en) New phenylamidine derivatives, processes for preparing them and their use as pharmaceutical compositions.
GR850831B (xx)
AU1174588A (en) Anticonvulsant agents
GR1002576B (el) Φαρμακευτικες συνθεσεις και μια μεθοδος παρασκευης τους.
DE69818492D1 (en) 7-methylthiooxomethyl- und 7-methylthiodioxomethyl-paclitaxele
NZ217356A (en) Benzamide derivatives and pharmaceutical compositions
IT1269740B (it) Derivati di combretastatine ad attivita' anti-tumorale e procedimento per la loro preparazione
UA23119A (uk) Психотропhий засіб