MX357273B - Uso de insulina de accion ultrarrapida. - Google Patents

Uso de insulina de accion ultrarrapida.

Info

Publication number
MX357273B
MX357273B MX2011001372A MX2011001372A MX357273B MX 357273 B MX357273 B MX 357273B MX 2011001372 A MX2011001372 A MX 2011001372A MX 2011001372 A MX2011001372 A MX 2011001372A MX 357273 B MX357273 B MX 357273B
Authority
MX
Mexico
Prior art keywords
acting insulin
insulin
ultrarapid acting
ultrarapid
administration
Prior art date
Application number
MX2011001372A
Other languages
English (en)
Other versions
MX2011001372A (es
Inventor
Richardson Peter
A Baughman Robert
Mann Alfred
Potocka Elizabeth
Hasager Boss Anders
Petrucci Richard
Howard Campbell
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mannkind Corp filed Critical Mannkind Corp
Publication of MX2011001372A publication Critical patent/MX2011001372A/es
Publication of MX357273B publication Critical patent/MX357273B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/545—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

La presente invención se refiere a una preparación de insulina de acción ultra-rápida inhalable que comprende fumaril-dicetopiperazi na (FDKP) asociada con insulina (insulina-FDKP) para usarse en el tratamiento de diabetes tipo 2 en un paciente: a) que está siendo tratado con un supresor de producción de glucosa hepática, pero no con una insulina basal; b) está en necesidad de control glucémico mejorado; y c) sería un candidato para el tratamiento de combinación con dicho supresor de producción de glucosa hepática y un secretagogo de insulina; en donde el tratamiento consiste en combinar el tratamiento del supresor de producción de glucosa hepática con la administración rutinaria de una preparación de insulina de acción-rápida inhalable que comprende insulina-FDKP con al menos una comida establecida, y en donde el supresor de producción de glucosa hepática es metformina.
MX2011001372A 2008-08-11 2009-08-11 Uso de insulina de accion ultrarrapida. MX357273B (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8794308P 2008-08-11 2008-08-11
US9749508P 2008-09-16 2008-09-16
US9751608P 2008-09-16 2008-09-16
US13886308P 2008-12-18 2008-12-18
PCT/US2009/053443 WO2010021879A2 (en) 2008-08-11 2009-08-11 Use of ultrarapid acting insulin

Publications (2)

Publication Number Publication Date
MX2011001372A MX2011001372A (es) 2011-03-04
MX357273B true MX357273B (es) 2018-07-03

Family

ID=41653492

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011001372A MX357273B (es) 2008-08-11 2009-08-11 Uso de insulina de accion ultrarrapida.
MX2019006731A MX2019006731A (es) 2008-08-11 2011-02-04 Uso de insulina de accion ultrarrapida.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2019006731A MX2019006731A (es) 2008-08-11 2011-02-04 Uso de insulina de accion ultrarrapida.

Country Status (14)

Country Link
US (12) US8258095B2 (es)
EP (2) EP3207942B1 (es)
JP (5) JP5869339B2 (es)
KR (3) KR20180037330A (es)
AU (3) AU2009283013B2 (es)
BR (1) BRPI0917535A8 (es)
CA (3) CA3022991C (es)
ES (1) ES2930673T3 (es)
MX (2) MX357273B (es)
MY (2) MY165651A (es)
RU (2) RU2519706C2 (es)
SG (2) SG10202010801RA (es)
TW (3) TWI532497B (es)
WO (1) WO2010021879A2 (es)

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