|
CN1020944C
(zh)
*
|
1990-01-30 |
1993-05-26 |
阿图尔-费希尔股份公司费希尔厂 |
紧固件
|
|
US9006175B2
(en)
|
1999-06-29 |
2015-04-14 |
Mannkind Corporation |
Potentiation of glucose elimination
|
|
US6515117B2
(en)
*
|
1999-10-12 |
2003-02-04 |
Bristol-Myers Squibb Company |
C-aryl glucoside SGLT2 inhibitors and method
|
|
WO2003080149A2
(en)
|
2002-03-20 |
2003-10-02 |
Mannkind Corporation |
Inhalation apparatus
|
|
US20080260838A1
(en)
*
|
2003-08-01 |
2008-10-23 |
Mannkind Corporation |
Glucagon-like peptide 1 (glp-1) pharmaceutical formulations
|
|
TWI254635B
(en)
*
|
2002-08-05 |
2006-05-11 |
Yamanouchi Pharma Co Ltd |
Azulene derivative and salt thereof
|
|
US7790681B2
(en)
|
2002-12-17 |
2010-09-07 |
Amylin Pharmaceuticals, Inc. |
Treatment of cardiac arrhythmias with GLP-1 receptor ligands
|
|
JP2006516257A
(ja)
*
|
2003-01-03 |
2006-06-29 |
ブリストル−マイヤーズ スクイブ カンパニー |
C−アリールグルコシドsglt2阻害剤の製造法
|
|
EA011515B1
(ru)
*
|
2003-08-01 |
2009-04-28 |
Янссен Фармацевтика Н.В. |
Замещенные бензимидазол-, бензтриазол- и бензимидазолон-о-глюкозиды
|
|
EP1679965A4
(de)
*
|
2003-08-01 |
2009-05-27 |
Janssen Pharmaceutica Nv |
Substituierte anellierte heterocyclische c-glycoside
|
|
RS20060320A
(sr)
*
|
2003-08-01 |
2008-08-07 |
Janssen Pharmaceutica N.V., |
Supstituisani indazol-o-glukozidi
|
|
SG130189A1
(en)
*
|
2003-08-01 |
2007-03-20 |
Janssen Pharmaceutica Nv |
Substituted indole-o-glucosides
|
|
US8785403B2
(en)
|
2003-08-01 |
2014-07-22 |
Mitsubishi Tanabe Pharma Corporation |
Glucopyranoside compound
|
|
WO2005012326A1
(en)
*
|
2003-08-01 |
2005-02-10 |
Tanabe Seiyaku Co., Ltd. |
Novel compounds having inhibitory activity against sodium-dependant transporter
|
|
JP2006514649A
(ja)
*
|
2003-12-17 |
2006-05-11 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
腎症の治療および予防のための組成物
|
|
EP1581246B1
(de)
*
|
2003-12-17 |
2013-01-16 |
Amylin Pharmaceuticals, LLC |
Zusammensetzungen zur behandlung und prevention von nephropathie
|
|
CA2557801C
(en)
|
2004-03-16 |
2013-06-25 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzol derivatives, drugs containing said compounds, the use thereof and method for the production thereof
|
|
JP4880591B2
(ja)
|
2004-06-04 |
2012-02-22 |
テバ ファーマシューティカル インダストリーズ リミティド |
イルベサルタンを含む医薬組成物
|
|
US7393836B2
(en)
*
|
2004-07-06 |
2008-07-01 |
Boehringer Ingelheim International Gmbh |
D-xylopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture
|
|
US20070293690A1
(en)
*
|
2004-07-08 |
2007-12-20 |
Hiroshi Tomiyama |
Process for Production of Azulene Derivatives and Intermediates for the Synthesis of the Same
|
|
DE102004034690A1
(de)
*
|
2004-07-17 |
2006-02-02 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Methyliden-D-xylopyranosyl-und Oxo-D-xylopyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
|
TW200606129A
(en)
|
2004-07-26 |
2006-02-16 |
Chugai Pharmaceutical Co Ltd |
Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same
|
|
WO2006010557A1
(de)
*
|
2004-07-27 |
2006-02-02 |
Boehringer Ingelheim International Gmbh |
D-glucopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
|
|
ATE486064T1
(de)
|
2004-08-20 |
2010-11-15 |
Mannkind Corp |
Katalyse der diketopiperazinsynthese
|
|
HUE025151T2
(en)
|
2004-08-23 |
2016-01-28 |
Mannkind Corp |
Diceto-piperazine salts for drug delivery
|
|
AR051446A1
(es)
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
|
DE102004048388A1
(de)
*
|
2004-10-01 |
2006-04-06 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
D-Pyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
|
TW200635599A
(en)
*
|
2004-12-16 |
2006-10-16 |
Boehringer Ingelheim Int |
Glucopyranosyl-substituted benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
|
TW200637869A
(en)
|
2005-01-28 |
2006-11-01 |
Chugai Pharmaceutical Co Ltd |
The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
|
|
TWI365186B
(en)
|
2005-01-31 |
2012-06-01 |
Mitsubishi Tanabe Pharma Corp |
Indole derivatives
|
|
AR053329A1
(es)
*
|
2005-01-31 |
2007-05-02 |
Tanabe Seiyaku Co |
Derivados de indol utiles como inhibidores de los transportadores de glucosa dependientes del sodio (sglt)
|
|
ATE445608T1
(de)
*
|
2005-02-23 |
2009-10-15 |
Boehringer Ingelheim Int |
Glucopyranosylsubstituierte ((hetero)arylethynyl- benzyl)-benzenderivative und deren verwendung als inhibitoren des natriumabhängigen glucose- cotransporters typ 2 (sglt2)
|
|
EP1874787B1
(de)
|
2005-04-15 |
2009-12-30 |
Boehringer Ingelheim International GmbH |
Glucopyranosyl-substituierte (heteroaryloxy-benzyl)-benzen-derivate als sglt-inhibitoren
|
|
EP1888562B1
(de)
|
2005-04-22 |
2014-06-18 |
Alantos Pharmaceuticals Holding, Inc. |
Dipeptidylpeptidase-iv-hemmer
|
|
US7723309B2
(en)
*
|
2005-05-03 |
2010-05-25 |
Boehringer Ingelheim International Gmbh |
Crystalline forms of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((R)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments
|
|
UA91546C2
(uk)
*
|
2005-05-03 |
2010-08-10 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ
|
|
US7772191B2
(en)
*
|
2005-05-10 |
2010-08-10 |
Boehringer Ingelheim International Gmbh |
Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
|
|
WO2007000445A1
(en)
*
|
2005-06-29 |
2007-01-04 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
|
TW200726755A
(en)
*
|
2005-07-07 |
2007-07-16 |
Astellas Pharma Inc |
A crystalline choline salt of an azulene derivative
|
|
EP1910390B1
(de)
|
2005-07-27 |
2010-05-19 |
Boehringer Ingelheim International GmbH |
Glucopyranosyl-substituierte ((hetero)cycloalyklethynyl-benzyl)-benzenderivative und deren verwendung als inhibitoren des natriumabhängigen glucose-cotransporters (sglt)
|
|
DE602006017566D1
(de)
*
|
2005-08-30 |
2010-11-25 |
Boehringer Ingelheim Pharma |
Glucopyranosyl-substituierte benzyl-derivate, medikamente mit solchen verbindungen, ihre verwendung und herstellungsverfahren dafür
|
|
ES2358051T3
(es)
*
|
2005-09-08 |
2011-05-05 |
Boehringer Ingelheim International Gmbh |
Formas cristalinas de 1-cloro-4-(beta-d-glucopiranos-1-il)-2-(4-etinil-bencil)-benceno, métodos para su preparación y su uso para preparar medicamentos.
|
|
KR101486397B1
(ko)
|
2005-09-14 |
2015-01-28 |
맨카인드 코포레이션 |
활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
|
|
AR056195A1
(es)
*
|
2005-09-15 |
2007-09-26 |
Boehringer Ingelheim Int |
Procedimientos para preparar derivados de (etinil-bencil)-benceno sustituidos de glucopiranosilo y compuestos intermedios de los mismos
|
|
AR057882A1
(es)
|
2005-11-09 |
2007-12-26 |
Novartis Ag |
Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra
|
|
AU2007216452A1
(en)
|
2006-02-15 |
2007-08-23 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture
|
|
KR20080096809A
(ko)
|
2006-02-22 |
2008-11-03 |
맨카인드 코포레이션 |
디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
|
|
TWI370818B
(en)
*
|
2006-04-05 |
2012-08-21 |
Astellas Pharma Inc |
Cocrystal of c-glycoside derivative and l-proline
|
|
PE20080697A1
(es)
|
2006-05-03 |
2008-08-05 |
Boehringer Ingelheim Int |
Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
|
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
|
US7919598B2
(en)
*
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
|
AU2014268177B2
(en)
*
|
2006-06-28 |
2016-05-19 |
Astrazeneca Ab |
Crystalline solvates and complexes of (1s) -1, 5-anhydro-1-c-(3-((phenyl)methyl)phenyl)-d-glucitol derivatives with amino acids as sglt2 inhibitors for the treatment of diabetes
|
|
TWI432446B
(zh)
|
2006-07-27 |
2014-04-01 |
Chugai Pharmaceutical Co Ltd |
稠環螺酮縮醇衍生物、及其做為糖尿病治療藥之使用
|
|
TWI403516B
(zh)
|
2006-07-27 |
2013-08-01 |
Chugai Pharmaceutical Co Ltd |
To replace spirocyclic alcohol derivatives, and its use as a therapeutic agent for diabetes
|
|
TWI418556B
(zh)
|
2006-07-27 |
2013-12-11 |
Mitsubishi Tanabe Pharma Corp |
吲哚衍生物
|
|
EP2054426A1
(de)
|
2006-08-15 |
2009-05-06 |
Boehringer Ingelheim International GmbH |
Glucopyranosylsubstituierte cyclopropylbenzolderivate, pharmazeutische zusammensetzungen, die solche verbindungen enthalten, ihre verwendung als sglt-inhibitoren und verfahren zu ihrer herstellung
|
|
EP2491947A3
(de)
|
2006-09-07 |
2012-10-17 |
GlaxoSmithKline Biologicals S.A. |
Impfstoff
|
|
JP5372759B2
(ja)
*
|
2006-09-21 |
2013-12-18 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グルコピラノシル−置換ジフルオロベンジル−ベンゼン誘導体、該化合物を含有する医薬品及びその使用と調製方法
|
|
TWI499414B
(zh)
*
|
2006-09-29 |
2015-09-11 |
Lexicon Pharmaceuticals Inc |
鈉與葡萄糖第2型共同運輸體(co-transporter 2)的抑制物與其應用方法
|
|
EP2072522A4
(de)
|
2006-10-13 |
2010-01-06 |
Chugai Pharmaceutical Co Ltd |
Thioglucose-spiroketal-derivat und seine verwendung als diabetes-therapeutikum
|
|
EP2086991A1
(de)
|
2006-10-27 |
2009-08-12 |
Boehringer Ingelheim International GmbH |
Kristalline form von 4-(?-d-glucopyranos-1-yl)-1-methyl-2-[4-((s)-tetrahydrofuran-3-yloxy)benzyl]benzol, verfahren zu deren herstellung und deren verwendung zur herstellung von medikamenten
|
|
WO2008070609A1
(en)
|
2006-12-04 |
2008-06-12 |
Janssen Pharmaceutica N.V. |
Thienyl-containing glycopyranosyl derivatives as antidiabetics
|
|
UY30730A1
(es)
*
|
2006-12-04 |
2008-07-03 |
Mitsubishi Tanabe Pharma Corp |
Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
|
|
WO2008075736A1
(ja)
*
|
2006-12-21 |
2008-06-26 |
Astellas Pharma Inc. |
C-グリコシド誘導体の製造方法及びその合成中間体
|
|
WO2008109591A1
(en)
*
|
2007-03-08 |
2008-09-12 |
Lexicon Pharmaceuticals, Inc. |
Phlorizin analogs as inhibitors of sodium glucose co-transporter 2
|
|
TW200904405A
(en)
|
2007-03-22 |
2009-02-01 |
Bristol Myers Squibb Co |
Pharmaceutical formulations containing an SGLT2 inhibitor
|
|
WO2008144346A2
(en)
*
|
2007-05-18 |
2008-11-27 |
Bristol-Myers Squibb Company |
Crystal structures of sglt2 inhibitors and processes for their preparation
|
|
CN103254119B
(zh)
*
|
2007-07-10 |
2016-07-06 |
莱西肯医药有限公司 |
钠-葡萄糖协同转运蛋白2的抑制剂及其用法
|
|
EP2183263B1
(de)
|
2007-07-26 |
2011-10-26 |
Lexicon Pharmaceuticals, Inc. |
Verfahren und verbindungen zur herstellung von natriumglucose-co-transporter-2-hemmern
|
|
CL2008002427A1
(es)
|
2007-08-16 |
2009-09-11 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2.
|
|
US7838499B2
(en)
|
2007-08-23 |
2010-11-23 |
Theracos, Inc. |
Benzylbenzene derivatives and methods of use
|
|
NZ600110A
(en)
|
2007-09-10 |
2013-03-28 |
Janssen Pharmaceutica Nv |
Process for the preparation of compounds useful as inhibitors of sglt
|
|
CN101969927A
(zh)
*
|
2007-10-24 |
2011-02-09 |
曼金德公司 |
预防glp-1不良影响的方法
|
|
EP2217602B1
(de)
*
|
2007-11-30 |
2018-08-29 |
Boehringer Ingelheim International GmbH |
1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-on- derivative und ihre verwendung als pde9a modulatoren zur behandlung von erkrankungen des zns
|
|
UA101004C2
(en)
|
2007-12-13 |
2013-02-25 |
Теракос, Инк. |
Derivatives of benzylphenylcyclohexane and use thereof
|
|
CN104387354A
(zh)
*
|
2007-12-27 |
2015-03-04 |
阿斯利康公司 |
Sglt2 抑制剂的晶体结构及其制备方法
|
|
CN103319445B
(zh)
*
|
2007-12-27 |
2016-01-20 |
阿斯利康公司 |
Sglt2抑制剂的晶体结构及其制备方法
|
|
CL2008003653A1
(es)
|
2008-01-17 |
2010-03-05 |
Mitsubishi Tanabe Pharma Corp |
Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
|
|
EP2236137B1
(de)
*
|
2008-01-31 |
2015-06-24 |
Astellas Pharma Inc. |
Pharmazeutische zusammensetzung zur behandlung von fettlebererkrankungen
|
|
UA105362C2
(en)
|
2008-04-02 |
2014-05-12 |
Бьорингер Ингельхайм Интернациональ Гмбх |
1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
|
|
JP5820269B2
(ja)
|
2008-05-22 |
2015-11-24 |
アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag |
Sglt2阻害剤を使用する高尿酸血症の治療方法およびsglt2阻害剤を含有する組成物
|
|
ES2929343T3
(es)
|
2008-06-13 |
2022-11-28 |
Mannkind Corp |
Inhalador de polvo seco accionado por aspiración para la administración de fármacos
|
|
US8485180B2
(en)
|
2008-06-13 |
2013-07-16 |
Mannkind Corporation |
Dry powder drug delivery system
|
|
MX2010014240A
(es)
|
2008-06-20 |
2011-03-25 |
Mankind Corp |
Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
|
|
CN102149280B
(zh)
*
|
2008-07-15 |
2017-05-24 |
泰拉科斯有限公司 |
氘化苄基苯衍生物及其使用方法
|
|
TWI494123B
(zh)
|
2008-08-11 |
2015-08-01 |
Mannkind Corp |
超快起作用胰島素之用途
|
|
ME02702B
(de)
*
|
2008-08-22 |
2017-10-20 |
Theracos Sub Llc |
Verfahren zur herstellung von sglt2-hemmern
|
|
AP2728A
(en)
*
|
2008-08-28 |
2013-08-31 |
Pfizer |
Dioxa-bicyclo[3.2.1.] octane-2,3,4-triol derivatives
|
|
PE20110383A1
(es)
|
2008-09-08 |
2011-07-15 |
Boehringer Ingelheim Int |
Pirazolopirimidinonas como inhibidores de la fosfodiesterasa 9a (pde9a)
|
|
US9056850B2
(en)
*
|
2008-10-17 |
2015-06-16 |
Janssen Pharmaceutica N.V. |
Process for the preparation of compounds useful as inhibitors of SGLT
|
|
US8314106B2
(en)
|
2008-12-29 |
2012-11-20 |
Mannkind Corporation |
Substituted diketopiperazine analogs for use as drug delivery agents
|
|
EP4684831A3
(de)
*
|
2009-02-13 |
2026-03-11 |
Boehringer Ingelheim International GmbH |
Sglt2-inhibitor zur verbesserung der glykämischen kontrolle
|
|
CN102387783A
(zh)
*
|
2009-02-13 |
2012-03-21 |
贝林格尔.英格海姆国际有限公司 |
包含吡喃葡萄糖基二苯基甲烷衍生物的药物组合物、其药物剂型、其制备方法及其在患者中改善血糖控制的用途
|
|
HUE050287T2
(hu)
|
2009-02-13 |
2020-11-30 |
Boehringer Ingelheim Int |
SGLT2-inhibitort, DPP-IV-inhibitort és adott esetben egy további antidiabetikus hatóanyagot tartalmazó gyógyászati készítmény és alkalmazásai
|
|
EP2226076A1
(de)
|
2009-02-25 |
2010-09-08 |
Henning Vollert |
Pflanzlicher Extrakt zur Prophylaxe und Behandlung von hyperglykämischen Erkrankungen
|
|
WO2010105094A1
(en)
|
2009-03-11 |
2010-09-16 |
Mannkind Corporation |
Apparatus, system and method for measuring resistance of an inhaler
|
|
CA2757231A1
(en)
*
|
2009-03-31 |
2010-10-07 |
Boehringer Ingelheim International Gmbh |
1-heterocyclyl-1,5-dihydro-pyrazolo [3,4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
|
|
MY182720A
(en)
*
|
2009-04-16 |
2021-02-03 |
Taisho Pharmaceutical Co Ltd |
Pharmaceutical compositions
|
|
MY157166A
(en)
|
2009-06-12 |
2016-05-13 |
Mankind Corp |
Diketopiperazine microparticles with defined specific surface areas
|
|
US20110009347A1
(en)
|
2009-07-08 |
2011-01-13 |
Yin Liang |
Combination therapy for the treatment of diabetes
|
|
US8772512B2
(en)
|
2009-07-10 |
2014-07-08 |
Janssen Pharmaceutica Nv |
Crystallisation process for 1-(β-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl] benzene
|
|
AR077859A1
(es)
*
|
2009-08-12 |
2011-09-28 |
Boehringer Ingelheim Int |
Compuestos para el tratamiento de trastornos del snc
|
|
NZ598318A
(en)
*
|
2009-09-30 |
2014-02-28 |
Boehringer Ingelheim Int |
Method for the preparation of a crystalline form of 1-chloro-4- (beta-d-glucopyranos-1-yl)-2-(4-((s)-tetrahydrofuran-3-yloxy)benzyl)benzene
|
|
BR112012007085B8
(pt)
|
2009-09-30 |
2021-05-25 |
Boehringer Ingelheim Int |
processos para a preparação de derivados de benzil-benzeno substituídos com glicopiranosila
|
|
UY32919A
(es)
|
2009-10-02 |
2011-04-29 |
Boehringer Ingelheim Int |
Composición farmacéutica, forma de dosificación farmacéutica, procedimiento para su preparación, mé todos para su tratamiento y sus usos
|
|
PH12012500698A1
(en)
|
2009-10-14 |
2016-05-27 |
Janssen Pharmaceutica Nv |
Process for the preparation of compounds useful as inhibitors of sglt2
|
|
DK2496583T3
(en)
|
2009-11-02 |
2015-02-02 |
Pfizer |
Dioxa-bicyclo [3.2.1] octane-2,3,4-triol DERIVATIVES
|
|
WO2011056889A1
(en)
|
2009-11-03 |
2011-05-12 |
Mannkind Corporation |
An apparatus and method for simulating inhalation efforts
|
|
ES2596291T3
(es)
|
2010-05-11 |
2017-01-05 |
Janssen Pharmaceutica, N.V. |
Formulaciones farmacéuticas que comprenden derivados de 1-(beta-d-glucopiranosil)-2-tienilmetilbenceno como inhibidores de sglt
|
|
WO2011153712A1
(en)
|
2010-06-12 |
2011-12-15 |
Theracos, Inc. |
Crystalline form of benzylbenzene sglt2 inhibitor
|
|
BR112012033060A2
(pt)
|
2010-06-21 |
2018-02-27 |
Mannkind Corp |
métodos de sistema de liberação de fármaco em pó seco
|
|
CN102372722A
(zh)
*
|
2010-08-10 |
2012-03-14 |
江苏恒瑞医药股份有限公司 |
C-芳基葡萄糖苷衍生物、其制备方法及其在医药上的应用
|
|
CA2807687C
(en)
|
2010-08-12 |
2019-01-08 |
Boehringer Ingelheim International Gmbh |
6-cycloalkyl-1, 5-dihydro-pyrazolo [3,4-d] pyrimidin-4-one derivatives and their use as pde9a inhibitors
|
|
WO2012025857A1
(en)
|
2010-08-23 |
2012-03-01 |
Hetero Research Foundation |
Cycloalkyl methoxybenzyl phenyl pyran derivatives as sodium dependent glucose co transporter (sglt2) inhibitors
|
|
US8809345B2
(en)
|
2011-02-15 |
2014-08-19 |
Boehringer Ingelheim International Gmbh |
6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders
|
|
WO2012109996A1
(zh)
|
2011-02-18 |
2012-08-23 |
上海璎黎科技有限公司 |
一种芳基糖苷类化合物及其制备方法和应用
|
|
CN102167715B
(zh)
*
|
2011-03-07 |
2013-04-24 |
上海惠斯生物科技有限公司 |
一种钠-葡萄糖协同运转蛋白-2原料药的共晶制备方法
|
|
AR085689A1
(es)
|
2011-03-07 |
2013-10-23 |
Boehringer Ingelheim Int |
Composiciones farmaceuticas de metformina, linagliptina y un inhibidor de sglt-2
|
|
AU2012236150B2
(en)
|
2011-04-01 |
2016-03-31 |
Mannkind Corporation |
Blister package for pharmaceutical cartridges
|
|
CN103596944B
(zh)
|
2011-04-13 |
2017-02-22 |
詹森药业有限公司 |
可用作sglt2的抑制剂的化合物的制备方法
|
|
US9035044B2
(en)
*
|
2011-05-09 |
2015-05-19 |
Janssen Pharmaceutica Nv |
L-proline and citric acid co-crystals of (2S, 3R, 4R, 5S,6R)-2-(3-((5-(4-fluorophenyl)thiopen-2-yl)methyl)4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
|
|
WO2012174472A1
(en)
|
2011-06-17 |
2012-12-20 |
Mannkind Corporation |
High capacity diketopiperazine microparticles
|
|
WO2013038429A2
(en)
|
2011-09-13 |
2013-03-21 |
Panacea Biotec Ltd. |
Novel sglt inhibitors
|
|
BR112014009686A2
(pt)
|
2011-10-24 |
2018-08-07 |
Mannkind Corp |
composição analgésica inalável, pó seco e método para tratar dor
|
|
AU2012330818B2
(en)
*
|
2011-10-31 |
2015-09-17 |
Julian Paul Henschke |
Crystalline and non-crystalline forms of SGLT2 inhibitors
|
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
|
US9192617B2
(en)
|
2012-03-20 |
2015-11-24 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
US9193751B2
(en)
|
2012-04-10 |
2015-11-24 |
Theracos, Inc. |
Process for the preparation of benzylbenzene SGLT2 inhibitors
|
|
EP3549587A1
(de)
|
2012-06-30 |
2019-10-09 |
BioActive Food GmbH |
Zusammensetzung zur behandlung von hyperglykämischen erkrankungen
|
|
AU2013289957B2
(en)
|
2012-07-12 |
2017-02-23 |
Mannkind Corporation |
Dry powder drug delivery systems and methods
|
|
US9145434B2
(en)
|
2012-07-26 |
2015-09-29 |
Boehringer Ingelheim International Gmbh |
Crystalline complex of 1-cyano-2-(4-cyclopropyl-benzyl)-4-(ss-d-glucopyranos-1-yl)-benzene, methods for its preparation and the use thereof for preparing medicaments
|
|
WO2014066856A1
(en)
|
2012-10-26 |
2014-05-01 |
Mannkind Corporation |
Inhalable influenza vaccine compositions and methods
|
|
CN103910769B
(zh)
|
2012-12-31 |
2018-10-02 |
上海璎黎药业有限公司 |
葡萄糖衍生物和脯氨酸的复合物、晶体、制备方法及应用
|
|
EP2774619B1
(de)
|
2013-03-04 |
2016-05-18 |
BioActive Food GmbH |
Zusammensetzung zur Behandlung von hyperglykämischen Erkrankungen
|
|
US8652527B1
(en)
|
2013-03-13 |
2014-02-18 |
Upsher-Smith Laboratories, Inc |
Extended-release topiramate capsules
|
|
KR102246914B1
(ko)
|
2013-03-15 |
2021-04-30 |
맨카인드 코포레이션 |
미세결정성 디케토피페라진 조성물 및 방법
|
|
US9101545B2
(en)
|
2013-03-15 |
2015-08-11 |
Upsher-Smith Laboratories, Inc. |
Extended-release topiramate capsules
|
|
CN104059042B
(zh)
*
|
2013-03-22 |
2017-02-08 |
正大天晴药业集团股份有限公司 |
C-三芳基葡萄糖苷类sglt-2抑制剂
|
|
PT2981269T
(pt)
|
2013-04-04 |
2023-10-10 |
Boehringer Ingelheim Vetmedica Gmbh |
Tratamento de distúrbios metabólicos em animais equinos
|
|
CA2812519A1
(en)
|
2013-04-05 |
2014-10-05 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
TR201901110T4
(tr)
|
2013-04-05 |
2019-02-21 |
Boehringer Ingelheim Int |
Empagliflozinin terapötik kullanımları.
|
|
US11813275B2
(en)
|
2013-04-05 |
2023-11-14 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
US20140303097A1
(en)
|
2013-04-05 |
2014-10-09 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
HK1215378A1
(zh)
|
2013-04-18 |
2016-08-26 |
勃林格殷格翰国际有限公司 |
药物组合物、治疗方法及其用途
|
|
CN114848614A
(zh)
|
2013-07-18 |
2022-08-05 |
曼金德公司 |
热稳定性干粉药物组合物和方法
|
|
EP3030294B1
(de)
|
2013-08-05 |
2020-10-07 |
MannKind Corporation |
Insufflationsvorrichtung
|
|
WO2015051484A1
(en)
|
2013-10-12 |
2015-04-16 |
Theracos, Inc. |
Preparation of hydroxy-benzylbenzene derivatives
|
|
CN105828815B
(zh)
|
2013-12-17 |
2020-03-27 |
勃林格殷格翰动物保健有限公司 |
猫科动物中代谢紊乱的治疗
|
|
PL3485890T3
(pl)
|
2014-01-23 |
2023-08-28 |
Boehringer Ingelheim Vetmedica Gmbh |
Inhibitory SGLT2 do leczenia zaburzeń metabolicznych u zwierząt psowatych
|
|
US10307464B2
(en)
|
2014-03-28 |
2019-06-04 |
Mannkind Corporation |
Use of ultrarapid acting insulin
|
|
KR102662473B1
(ko)
|
2014-04-01 |
2024-05-03 |
베링거잉겔하임베트메디카게엠베하 |
말과 동물에서 대사 장애의 치료
|
|
CN105001213B
(zh)
|
2014-04-14 |
2020-08-28 |
上海迪诺医药科技有限公司 |
C-芳基糖苷衍生物、其药物组合物、制备方法及应用
|
|
WO2015173584A1
(en)
*
|
2014-05-16 |
2015-11-19 |
Astrazeneca Ab |
Method for suppressing glucagon secretion of an sglt2 inhibitor
|
|
EP2944311A1
(de)
|
2014-05-16 |
2015-11-18 |
BioActive Food GmbH |
Kombination von biologisch aktiven Substanzen zur Behandlung von hyperglykämischen Erkrankungen
|
|
US9676741B1
(en)
|
2014-06-23 |
2017-06-13 |
Sun Pharmaceutical Industries Limited |
Co-crystal of dapagliflozin with citric acid
|
|
DK3197429T3
(da)
|
2014-09-25 |
2024-08-26 |
Boehringer Ingelheim Vetmedica Gmbh |
Kombinationsbehandling med sglt2-hæmmere og dopaminagonister til forebyggelse af metaboliske lidelser af dyr i hestefamilien
|
|
US10561806B2
(en)
|
2014-10-02 |
2020-02-18 |
Mannkind Corporation |
Mouthpiece cover for an inhaler
|
|
WO2016161995A1
(en)
|
2015-04-08 |
2016-10-13 |
Zentiva, K.S. |
Solid forms of amorphous dapagliflozin
|
|
CN104788438B
(zh)
*
|
2015-05-04 |
2018-02-02 |
南京华威医药科技集团有限公司 |
恩格列净b晶型及其制备
|
|
WO2017032799A1
(en)
|
2015-08-27 |
2017-03-02 |
Boehringer Ingelheim Vetmedica Gmbh |
Liquid pharmaceutical compositions comprising sglt-2 inhibitors
|
|
US20170071970A1
(en)
|
2015-09-15 |
2017-03-16 |
Janssen Pharmaceutica Nv |
Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
|
|
EP3349762B1
(de)
|
2015-09-15 |
2021-08-25 |
Laurus Labs Limited |
Co-kristalle von sglt2-inhibitoren, verfahren zu deren herstellung und pharmazeutische zusammensetzungen daraus
|
|
WO2017060925A1
(en)
*
|
2015-10-09 |
2017-04-13 |
Harman Finochem Limited |
Novel pipecolic acid co-crystals of dapagliflozin and process for the preparation thereof
|
|
ITUB20156048A1
(it)
*
|
2015-12-01 |
2017-06-01 |
Dipharma Francis Srl |
Co-cristallo e forma amorfa di un farmaco antidiabetico
|
|
WO2017141202A1
(en)
|
2016-02-17 |
2017-08-24 |
Lupin Limited |
Complex of sglt2 inhibitor and process for preparation thereof
|
|
US10793588B2
(en)
|
2016-05-28 |
2020-10-06 |
Ji Lin Hui Sheng Bio-Pharmaceutical Co., Ltd. |
Crystal form of sodium-glucose cotransporter 2 inhibitor
|
|
WO2018002673A1
(en)
|
2016-07-01 |
2018-01-04 |
N4 Pharma Uk Limited |
Novel formulations of angiotensin ii receptor antagonists
|
|
AU2017357589B2
(en)
|
2016-11-10 |
2023-05-11 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
CN108239055B
(zh)
*
|
2016-12-23 |
2023-07-18 |
杭州领业医药科技有限公司 |
一种thr1442 l-天冬氨酸共晶、其制备方法及药物组合物
|
|
WO2020016335A1
(en)
|
2018-07-19 |
2020-01-23 |
Astrazeneca Ab |
Methods of treating hfpef employing dapagliflozin and compositions comprising the same
|
|
KR20210065974A
(ko)
*
|
2018-09-26 |
2021-06-04 |
렉시컨 파마슈티컬스 인코퍼레이티드 |
N-(1-((2-(디메틸아미노)에틸)아미노)-2-메틸-1-옥소프로판-2-일)-4-(4-(2-메틸-5-((2s,3r,4r,5s,6r)-3,4,5-트리히드록시-6-(메틸티오)테트라히드로-2h-피란-2-일)벤질)페닐)부탄아미드의 결정질 형태 및 그의 합성 방법
|
|
MY209787A
(en)
|
2019-07-26 |
2025-08-04 |
Dongbao Purple Star Hangzhou Biopharmaceutical Co Ltd |
Sglts/dpp4 inhibitor and application thereof
|
|
SI4188389T1
(sl)
|
2020-07-27 |
2025-11-28 |
Astrazeneca Ab |
Dapagliflozin za uporabo pri postopkih zdravljenja kronične ledvične bolezni
|
|
TW202220672A
(zh)
|
2020-07-27 |
2022-06-01 |
瑞典商阿斯特捷利康公司 |
用達格列淨治療慢性腎臟病之方法
|
|
CN113149828A
(zh)
*
|
2021-03-31 |
2021-07-23 |
山东寿光增瑞化工有限公司 |
一种5-溴-2-甲基苯甲酸的制备方法
|
|
US20240212818A1
(en)
|
2021-04-01 |
2024-06-27 |
Astrazeneca Uk Limited |
Systems and methods for managing prediabetes with a gliflozin sodiumglucose cotransport 2 inhibitor pharmaceutical composition
|
|
US20250108065A1
(en)
|
2022-01-26 |
2025-04-03 |
Astrazeneca Ab |
Methods of treating prediabetes or reducing the risk of developing type 2 diabetes with dapagliflozin
|
|
WO2025125513A1
(en)
|
2023-12-15 |
2025-06-19 |
AstraZeneca Ireland Limited |
Sglt2 inhibitors and baxdrostat for treating chronic kidney disease and hypertension
|