JP6377613B2 - 可撓性のある拡張可能な電極及びパルスパワーを管腔内送達する方法 - Google Patents
可撓性のある拡張可能な電極及びパルスパワーを管腔内送達する方法 Download PDFInfo
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Description
(1) 細長部材と、
前記細長部材に沿って配置され、且つ軸線に沿って伸びる第1電極であって、エネルギー源に結合するように構成されている近位端部と、組織処理領域に結合し、且つアブレーションのためのエネルギーをかけるように構成されている面とを有する、第1電極と、
近位端部及び遠位端部を有し、且つ前記軸線に沿って伸びる第1拡張可能部であって、前記第1電極の第1外周を画定し、且つそれと関連付けられた前記軸線に対する第1直径を有する、第1拡張可能部と、を備え、前記第1拡張可能部は、少なくとも1つの第1枠組み部材を含む第1枠組みを含み、
前記第1枠組みは、前記第1拡張可能部を収縮した状態から拡張した状態に移行させるように選択的に拡張可能であり、且つ前記第1枠組みは、前記第1拡張可能部を前記拡張した状態から前記収縮した状態に移行させるように選択的に収縮可能であり、前記第1枠組みが拡張した際には前記第1直径が拡張し、前記第1拡張可能部が前記収縮した状態から前記拡張した状態に移行し、前記第1枠組みが収縮した際には前記第1直径が収縮し、前記第1拡張可能部が前記拡張した状態から前記収縮した状態に移行する、電気的アブレーションデバイス。
(2) 前記第1電極は第1可撓部を含み、前記第1拡張可能部の少なくとも一部分は前記第1可撓部の少なくとも一部分を含む、実施態様1に記載の電気的アブレーションデバイス。
(3) 前記第1枠組みは、生物学的管腔に対して前記生物学的管腔の周囲付近の2つ又は3つ以上の位置で、周方向に接触するように前記第1直径を拡張させるように拡張することが可能な、実施態様1に記載の電気的アブレーションデバイス。
(4) 1つ又は2つ以上の第1枠組み部材は、それに関連付けられた記憶形状及びそれに関連付けられた維持された形状とを有し、前記1つ又は2つ以上の第1枠組み部材は、前記第1枠組みを拡張し且つ収縮させるために、前記記憶形状と前記維持された形状との間を移行することが可能な、実施態様1に記載の電気的アブレーションデバイス。
(5) 前記1つ又は2つ以上の第1枠組み部材を、前記維持された形状に維持するように構成されている維持構造体を更に備える、実施態様4に記載の電気的アブレーションデバイス。
(7) 前記1つ又は2つ以上の第1枠組み部材は編組部を含み、前記編組部は、前記拡張可能部の前記近位端部と遠位端部との間に伸び、前記拡張可能部は、前記編組部が前記シースの前記遠位端部から展開された際に、前記収縮した状態から前記拡張した状態に移行するように構成されており、前記第1枠組みは、前記収縮した状態における長さが前記拡張した状態での長さよりも長い、実施態様6に記載の電気的アブレーションデバイス。
(8) 前記第1枠組みが前記第1拡張可能部内に空洞を画定し、前記空洞は、前記第1拡張可能部が前記収縮した状態になった際の、関連付けられた第1容積を有し、且つ前記第1拡張可能部が前記拡張した状態になった際の、関連付けられた第2容積を有し、前記第1容積は前記第2容積と実質的に同じである、実施態様1に記載の電気的アブレーションデバイス。
(9) 1つ又は2つ以上の第1枠組み部材は、関連付けられた低温時形状と、関連付けられた高温時形状との間を移行することが可能であり、前記低温時形状は前記収縮した状態に対応し且つ前記高温時形状は前記拡張した状態に対応し、前記拡張可能部を前記収縮した状態から前記拡張した状態に移行させることは、前記1つ又は2つ以上の第1枠組み部材を前記低温時形状から前記高温時形状に移行させるのに十分な温度の上昇を含む、実施態様1に記載の電気的アブレーションデバイス。
(10) 前記第1枠組みは、前記第1枠組み内の1つ又は2つ以上の第1枠組み部材を結合するよう構成されている近位カプラー及び遠位カプラーをさらに含み、前記近位カプラー及び遠位カプラーは、ある距離だけ離れており、前記収縮した状態から前記拡張した状態に移行させることは、前記近位カプラーと前記遠位カプラーとの間の前記距離を減らすことを含む、実施態様1に記載の電気的アブレーションデバイス。
(12) 前記1つ又は2つ以上の第1枠組み部材は、前記近位カプラーと前記遠位カプラーとの間に伸びる編組部を含み、前記近位カプラーは前記編組部の近位部と結合し且つ前記遠位カプラーは前記編組部の遠位部と結合する、実施態様10に記載の電気的アブレーションデバイス。
(13) 前記収縮した状態から前記拡張した状態に移行させることは、1つ又は2つ以上の第1枠組み部材の近位部と遠位部との間での相対的回転を含む、実施態様1に記載の電気的アブレーションデバイス。
(14) 前記1つ又は2つ以上の第1枠組み部材はコイルを含み、前記第1枠組みは前記コイルの近位部に結合する近位カプラーと、前記コイルの遠位部に結合する遠位カプラーとを更に含み、前記近位カプラー及び遠位カプラーはある距離だけ分離され、前記収縮した状態から前記拡張した状態に移行させることは、前記近位カプラーと前記遠位カプラーとの間の前記距離を減らすことを更に含む、実施態様13に記載の電気的アブレーションデバイス。
(15) 前記細長部材に沿って配置され、且つ前記軸線に沿って伸びる第2電極であって、エネルギー源に結合するように構成されている近位端部と、前記組織処理領域に結合するように構成されている面とを有する、第2電極と、
近位端部及び遠位端部を有し、且つ前記軸線に沿って伸びる第2拡張可能部であって、前記第2電極の第2外周を画定し、且つそれと関連付けられた前記軸線に対する第2直径を有する、第2拡張可能部と、を更に備え、前記第2拡張可能部は、1つ又は2つ以上の第2枠組み部材を含む第2枠組みを含み、
前記第2枠組みは、前記第2拡張可能部を収縮した状態から拡張した状態に移行させるように選択的に拡張可能であり、且つ前記第2枠組みは、前記第2拡張可能部を前記拡張した状態から前記収縮した状態に移行させるように選択的に収縮可能であり、前記第2枠組みが拡張した際には前記第2直径が拡張し、前記第2拡張可能部が前記収縮した状態から前記拡張した状態に移行し、前記第2枠組みが収縮した際には前記第2直径が収縮し、前記第2拡張可能部が前記拡張した状態から前記収縮した状態に移行する、実施態様1に記載の電気的アブレーションデバイス。
(17) 実施態様1に記載のデバイスを入手することと、
前記第1電極を、生物学的管腔を含む組織処理領域に送達することと、
前記第1電極を拡張することと、
前記第1電極を、処理される組織の近位の前記管腔の壁に接触させることと、
前記第1電極を用いて、不可逆的な電気穿孔によって組織に細胞死を誘発するのに十分な電気的パルスの1つ又は2つ以上のシーケンスを、前記処理される組織に加えて、組織処理することと、を含む、電気外科的に組織処理する方法。
(18) 前記枠組み部材は、前記拡張可能部に沿って伸びるコイルを含み、前記組織処理することは、前記管腔全体を連続的に処理するように、前記コイルを前記管腔内で第1方向に回転させることを更に含む、実施態様17に記載の電気外科的に組織処理する方法。
(19) 軸線に沿って伸び、且つエネルギー源に結合するよう構成されている近位端部と、組織処理領域に結合されアブレーションのためのエネルギーをかけるよう構成されている面とを有する、拡張可能な電極を含む電気的アブレーションデバイスであって、前記拡張可能な電極が、
関連付けられた前記軸線周りの直径を有する外周を画定する拡張可能部であって、前記拡張可能部は縮んだ状態と拡張した状態との間を移行することが可能であり、前記拡張可能部が前記縮んだ状態から前記拡張した状態に移行した際に前記直径が増加し、前記拡張可能部が前記拡張した状態から前記縮んだ状態に移行した際に前記直径が減少する、拡張可能部と、
前記拡張可能部に沿って配置される1つ又は2つ以上の枠組み部材であって、前記1つ又は2つ以上の枠組み部材の少なくとも1つは、形状記憶弾性材を有し、前記1つ又は2つ以上の枠組み部材の前記少なくとも1つは、前記拡張可能部の前記縮んだ状態に関連づけられたマルテンサイト形態に、維持構造体により維持されるように構成されており、オーステナイト温度においては、前記1つ又は2つ以上の枠組み部材の前記少なくとも1つは、前記維持構造体により解放された際の前記拡張可能部の前記拡張した状態に関連付けられたオーステナイト形態に復帰するように構成されている、枠組み部材と、を含んでいる、電気的アブレーションデバイス。
(20) 前記維持構造体は、前記1つ又は2つ以上の枠組み部材の前記少なくとも1つを、遠位部内に受容するように構成されているチャネルを画定するシースを含み、前記1つ又は2つ以上の枠組み部材の前記少なくとも1つは前記シースの前記遠位部から展開可能であり、前記1つ又は2つ以上の枠組み部材の前記少なくとも1つが前記シースの前記遠位部から展開される際には、前記1つ又は2つ以上の枠組み部材の前記少なくとも1つは、前記維持構造体によって解放される、実施態様19に記載の拡張可能な電極。
Claims (4)
- 細長部材と、
前記細長部材に沿って配置され、且つ軸線に沿って伸びる第1電極であって、エネルギー源に結合するように構成されている近位端部と、組織処理領域に結合し、且つアブレーションのためのエネルギーをかけるように構成されている面とを有する、第1電極と、
近位端部及び遠位端部を有し、且つ前記軸線に沿って伸びる第1拡張可能部であって、前記第1電極の第1外周を画定し、且つそれと関連付けられた前記軸線に対する第1直径を有する、第1拡張可能部と、を備え、前記第1拡張可能部は、少なくとも1つの第1枠組み部材を含む第1枠組みを含み、
前記第1枠組みは、前記第1拡張可能部を収縮した状態から拡張した状態に移行させるように選択的に拡張可能であり、且つ前記第1枠組みは、前記第1拡張可能部を前記拡張した状態から前記収縮した状態に移行させるように選択的に収縮可能であり、前記第1枠組みが拡張した際には前記第1直径が拡張し、前記第1拡張可能部が前記収縮した状態から前記拡張した状態に移行し、前記第1枠組みが収縮した際には前記第1直径が収縮し、前記第1拡張可能部が前記拡張した状態から前記収縮した状態に移行し、
前記第1枠組みは、前記第1枠組み内の前記少なくとも1つの第1枠組み部材を結合するよう構成されている近位カプラー及び遠位カプラーをさらに含み、前記近位カプラー及び遠位カプラーは、ある距離だけ離れており、前記収縮した状態から前記拡張した状態に移行させることは、前記近位カプラーと前記遠位カプラーとの間の前記距離を減らすことを含み、
前記第1枠組みは、更に、コイル状である前記少なくとも1つの第1枠組み部材の周りに設けられた導電性スリーブを含み、前記少なくとも1つの第1枠組み部材は、前記導電性スリーブの内側に配置されるようになっており、
前記近位カプラーおよび前記遠位カプラーの内の少なくとも一方に設けられたカプラーねじ山が、前記細長部材に設けられたねじ山上を回転することにより、前記カプラーねじ山が設けられた前記近位カプラーおよび前記遠位カプラーの内の前記少なくとも一方が、前記軸線に沿って移動して、前記近位カプラーと前記遠位カプラーとの間の前記距離が減らされ、前記第1拡張可能部が前記収縮した状態から前記拡張した状態に移行するようになっている、電気的アブレーションデバイス。 - 前記第1電極は第1可撓部を含み、前記第1拡張可能部の少なくとも一部分は前記第1可撓部の少なくとも一部分を含む、請求項1に記載の電気的アブレーションデバイス。
- 前記第1枠組みは、生物学的管腔に対して前記生物学的管腔の周囲付近の2つ又は3つ以上の位置で、周方向に接触するように前記第1直径を拡張させるように拡張することが可能な、請求項1に記載の電気的アブレーションデバイス。
- 前記少なくとも1つの第1枠組み部材は、それに関連付けられた記憶形状及びそれに関連付けられた維持された形状とを有し、前記少なくとも1つの第1枠組み部材は、前記第1枠組みを拡張し且つ収縮させるために、前記記憶形状と前記維持された形状との間を移行することが可能な、請求項1に記載の電気的アブレーションデバイス。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US13/565,307 | 2012-08-02 | ||
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PCT/US2013/052250 WO2014022221A1 (en) | 2012-08-02 | 2013-07-26 | Flexible expandable electrode and method of intraluminal delivery of pulsed power |
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Cited By (1)
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WO2021030256A1 (en) * | 2019-08-13 | 2021-02-18 | Boston Scientific Scimed, Inc. | Expandable ablation devices |
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US10314649B2 (en) | 2019-06-11 |
BR112015002311B1 (pt) | 2022-05-03 |
US20140039491A1 (en) | 2014-02-06 |
WO2014022221A1 (en) | 2014-02-06 |
CN104703557A (zh) | 2015-06-10 |
EP2879606A1 (en) | 2015-06-10 |
CN104703557B (zh) | 2018-11-16 |
BR112015002311A2 (pt) | 2017-07-04 |
IN2015DN00815A (ja) | 2015-06-12 |
JP2015524310A (ja) | 2015-08-24 |
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