|
EP3623473A1
(en)
|
2005-03-31 |
2020-03-18 |
Chugai Seiyaku Kabushiki Kaisha |
Process for production of polypeptide by regulation of assembly
|
|
KR101463631B1
(ko)
|
2006-03-31 |
2014-11-19 |
추가이 세이야쿠 가부시키가이샤 |
항체의 혈중 동태를 제어하는 방법
|
|
EP2009101B1
(en)
|
2006-03-31 |
2017-10-25 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody modification method for purifying bispecific antibody
|
|
AU2008234248C1
(en)
|
2007-03-29 |
2015-01-22 |
Genmab A/S |
Bispecific antibodies and methods for production thereof
|
|
EP4119579A1
(en)
*
|
2007-05-31 |
2023-01-18 |
Genmab A/S |
Stable igg4 antibodies
|
|
PH12021552811A1
(en)
|
2007-09-26 |
2022-11-21 |
Chugai Pharmaceutical Co Ltd |
Modified antibody constant region
|
|
RU2510400C9
(ru)
|
2007-09-26 |
2014-07-20 |
Чугаи Сейяку Кабусики Кайся |
Способ модификации изоэлектрической точки антитела с помощью аминокислотных замен в cdr
|
|
DK2235064T3
(en)
*
|
2008-01-07 |
2016-01-11 |
Amgen Inc |
A process for the preparation of heterodimeric Fc molecules using electrostatic control effects
|
|
US9228017B2
(en)
|
2009-03-19 |
2016-01-05 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
|
EP3674317B1
(en)
|
2009-03-19 |
2024-12-11 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
US10150808B2
(en)
|
2009-09-24 |
2018-12-11 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant regions
|
|
JP5889181B2
(ja)
|
2010-03-04 |
2016-03-22 |
中外製薬株式会社 |
抗体定常領域改変体
|
|
JP6040148B2
(ja)
|
2010-04-20 |
2016-12-07 |
ゲンマブ エー／エス |
ヘテロ二量体抗体Ｆｃ含有タンパク質およびその産生方法
|
|
EP2569337A1
(en)
|
2010-05-14 |
2013-03-20 |
Rinat Neuroscience Corp. |
Heterodimeric proteins and methods for producing and purifying them
|
|
CN103153339B
(zh)
*
|
2010-05-27 |
2021-05-04 |
根马布股份公司 |
针对her2表位的单克隆抗体
|
|
AU2016201799B2
(en)
*
|
2010-05-27 |
2017-09-07 |
Genmab A/S |
Monoclonal antibodies aganst HER2 epitope
|
|
CN107253992B
(zh)
*
|
2010-05-27 |
2022-03-11 |
根马布股份公司 |
针对her2的单克隆抗体
|
|
US8637641B2
(en)
|
2010-07-29 |
2014-01-28 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
|
US9334331B2
(en)
|
2010-11-17 |
2016-05-10 |
Chugai Seiyaku Kabushiki Kaisha |
Bispecific antibodies
|
|
ES2693232T3
(es)
|
2010-11-30 |
2018-12-10 |
Chugai Seiyaku Kabushiki Kaisha |
Agente terapéutico que induce citotoxicidad
|
|
JP6177231B2
(ja)
*
|
2011-04-20 |
2017-08-09 |
ゲンマブ エー／エス |
Ｈｅｒ２に対する二重特異性抗体
|
|
US20140170148A1
(en)
*
|
2011-04-20 |
2014-06-19 |
Genmab A/S |
Bispecific antibodies against her2
|
|
WO2012143524A2
(en)
|
2011-04-20 |
2012-10-26 |
Genmab A/S |
Bispecific antibodies against her2 and cd3
|
|
EP2699260B1
(en)
*
|
2011-04-20 |
2024-11-20 |
Genmab A/S |
Bispecifc antibodies against her2
|
|
UA117901C2
(uk)
|
2011-07-06 |
2018-10-25 |
Ґенмаб Б.В. |
Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування
|
|
KR20200120743A
(ko)
*
|
2011-07-06 |
2020-10-21 |
젠맵 비. 브이 |
항체 변이체 및 그의 용도
|
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
CN107266577B
(zh)
|
2011-10-11 |
2022-09-13 |
弗·哈夫曼-拉罗切有限公司 |
双特异性抗体的改进的组装
|
|
US10344050B2
(en)
*
|
2011-10-27 |
2019-07-09 |
Genmab A/S |
Production of heterodimeric proteins
|
|
RU2681885C2
(ru)
|
2011-10-31 |
2019-03-13 |
Чугаи Сейяку Кабусики Кайся |
Антигенсвязывающая молекула с регулируемой конъюгацией между тяжелой цепью и легкой цепью
|
|
ES2843402T3
(es)
|
2011-12-13 |
2021-07-16 |
Engeneic Molecular Delivery Pty Ltd |
Minicélulas intactas de origen bacteriano para la administración de agentes terapéuticos a tumores cerebrales
|
|
LT2802607T
(lt)
*
|
2012-01-13 |
2018-02-12 |
Julius-Maximilians-Universität Würzburg |
Dviguba antigeno indukuota dvišalė funkcinė komplementacija
|
|
US9090694B2
(en)
|
2012-04-30 |
2015-07-28 |
Janssen Biotech, Inc. |
ST2L antibody antagonists
|
|
ES2843054T3
(es)
*
|
2012-05-10 |
2021-07-15 |
Zymeworks Inc |
Construcciones heteromultiméricas de cadenas pesadas de inmunoglobulina con mutaciones en el dominio Fc
|
|
AU2013258844B2
(en)
*
|
2012-05-10 |
2017-12-21 |
Zymeworks Bc Inc. |
Single-arm monovalent antibody constructs and uses thereof
|
|
EP3632462A1
(en)
|
2012-07-06 |
2020-04-08 |
Genmab B.V. |
Dimeric protein with triple mutations
|
|
EP2869845B1
(en)
|
2012-07-06 |
2019-08-28 |
Genmab B.V. |
Dimeric protein with triple mutations
|
|
TWI855488B
(zh)
|
2012-08-24 |
2024-09-11 |
日商中外製藥股份有限公司 |
FcγRIIb特異性Fc區域變異體
|
|
KR20150076172A
(ko)
*
|
2012-09-25 |
2015-07-06 |
그렌마크 파머수티칼스 에스. 아. |
이질-이합체 면역글로불린의 정제
|
|
US9695228B2
(en)
|
2012-11-21 |
2017-07-04 |
Janssen Biotech, Inc. |
EGFR and c-Met fibronectin type III domain binding molecules
|
|
US20170275367A1
(en)
|
2012-11-21 |
2017-09-28 |
Janssen Biotech, Inc. |
Bispecific EGFR/C-Met Antibodies
|
|
LT2922872T
(lt)
*
|
2012-11-21 |
2018-12-27 |
Janssen Biotech, Inc. |
Bispecifiniai egfr/c-met antikūnai
|
|
EA032681B1
(ru)
|
2012-11-27 |
2019-07-31 |
Аджоу Юниверсити Индастри-Академик Кооперейшн Фаундейшн |
ГЕТЕРОДИМЕР Fc ИММУНОГЛОБУЛИНА, СОДЕРЖАЩИЙ ВАРИАНТ ДОМЕНА CH3 ДЛЯ ОБРАЗОВАНИЯ АНТИТЕЛА ИЛИ ГИБРИДНОГО БЕЛКА С ГЕТЕРОМЕРНЫМ Fc С ВЫСОКОЙ ЭФФЕКТИВНОСТЬЮ, СПОСОБ ДЛЯ ЕГО ПОЛУЧЕНИЯ И ИСПОЛЬЗОВАНИЯ
|
|
MX385344B
(es)
|
2012-11-28 |
2025-03-18 |
Zymeworks Bc Inc |
Pares de cadena pesada-cadena ligera de inmunoglobulina modificados genéticamente y usos de estos.
|
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
|
KR20200134340A
(ko)
*
|
2013-01-10 |
2020-12-01 |
젠맵 비. 브이 |
인간 IgG1 Fc 영역 변이체 및 그의 용도
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
CA3211863A1
(en)
|
2013-01-14 |
2014-07-17 |
Xencor, Inc. |
Novel heterodimeric proteins
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
WO2014113510A1
(en)
|
2013-01-15 |
2014-07-24 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
|
EP3620468A1
(en)
|
2013-02-05 |
2020-03-11 |
EngMab Sàrl |
Method for the selection of antibodies against bcma
|
|
CA2906526C
(en)
|
2013-03-15 |
2022-12-06 |
Ellen Chi |
Interferon alpha and omega antibody antagonists
|
|
CN110143999B
(zh)
|
2013-03-15 |
2023-12-05 |
酵活英属哥伦比亚省公司 |
具细胞毒性和抗有丝分裂的化合物以及其使用方法
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10544187B2
(en)
|
2013-03-15 |
2020-01-28 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
|
CN105229032A
(zh)
|
2013-03-18 |
2016-01-06 |
比奥塞罗克斯产品公司 |
人源化抗cd134(ox40)抗体及其应用
|
|
US11267868B2
(en)
|
2013-04-02 |
2022-03-08 |
Chugai Seiyaku Kabushiki Kaisha |
Fc region variant
|
|
JP6618893B2
(ja)
|
2013-04-29 |
2019-12-11 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
Ｆｃ受容体結合が変更された非対称抗体および使用方法
|
|
KR102282134B1
(ko)
|
2013-04-29 |
2021-07-27 |
에프. 호프만-라 로슈 아게 |
인간 fcrn-결합 변형된 항체 및 사용 방법
|
|
SG10201810481UA
(en)
*
|
2013-04-29 |
2018-12-28 |
Hoffmann La Roche |
Fcrn-binding abolished anti-igf-1r antibodies and their use in the treatment of vascular eye diseases
|
|
BR112015029788B1
(pt)
*
|
2013-05-31 |
2024-01-02 |
Zymeworks Inc |
HETERO-MULTÍMERO, USO E MÉTODO PARA PREPARAR DO MESMO, COMPOSIÇÃO FARMACÊUTICA E MÉTODO PARA REDUZIR FUNÇÃO EFETORA DE UM CONSTRUTO IgG FC
|
|
PT3016681T
(pt)
|
2013-07-05 |
2020-03-26 |
Genmab As |
Anticorpos humanizados ou quiméricos cd3
|
|
ES2881306T3
(es)
|
2013-09-27 |
2021-11-29 |
Chugai Pharmaceutical Co Ltd |
Método para la producción de heteromultímeros de polipéptidos
|
|
CA2926262C
(en)
|
2013-10-14 |
2025-06-17 |
Janssen Biotech, Inc. |
CYSTEINE MODIFIED TYPE III FIBRONECTIN DOMAIN BINDING MOLECULES (FN3)
|
|
US9493563B2
(en)
|
2013-11-04 |
2016-11-15 |
Glenmark Pharmaceuticals S.A. |
Production of T cell retargeting hetero-dimeric immunoglobulins
|
|
SI3065774T1
(sl)
|
2013-11-06 |
2021-11-30 |
Janssen Biotech, Inc. |
Protitelesa proti CCL17
|
|
KR102551410B1
(ko)
|
2013-11-11 |
2023-07-04 |
추가이 세이야쿠 가부시키가이샤 |
개변된 항체 가변영역을 포함하는 항원 결합 분자
|
|
PT3083689T
(pt)
|
2013-12-17 |
2020-08-27 |
Genentech Inc |
Anticorpos anti-cd3 e métodos de utilização
|
|
JP6560681B2
(ja)
|
2013-12-27 |
2019-08-14 |
ザイムワークス インコーポレイティド |
薬物結合体のためのスルホンアミド含有連結系
|
|
CA2932364A1
(en)
|
2014-01-15 |
2015-07-23 |
F. Hoffmann-La Roche Ag |
Fc-region variants with improved protein a-binding
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
EP3105252B1
(en)
|
2014-02-12 |
2019-07-24 |
Michael Uhlin |
Bispecific antibodies for use in stem cell transplantation
|
|
US9732154B2
(en)
|
2014-02-28 |
2017-08-15 |
Janssen Biotech, Inc. |
Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
|
|
UY36032A
(es)
|
2014-03-14 |
2015-10-30 |
Novartis Ag |
Moléculas de anticuerpo que se unen a lag-3 y usos de las mismas
|
|
US20170335281A1
(en)
|
2014-03-15 |
2017-11-23 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
|
CN113150163A
(zh)
*
|
2014-03-21 |
2021-07-23 |
X博迪公司 |
双特异性抗原结合多肽
|
|
BR112016022385A2
(pt)
|
2014-03-28 |
2018-06-19 |
Xencor, Inc |
anticorpos específicos que se ligam a cd38 e cd3
|
|
EP3825326A1
(en)
|
2014-04-01 |
2021-05-26 |
Adimab, LLC |
Multispecific antibody analogs comprising a common light chain, and methods of their preparation and use
|
|
CN106459206B
(zh)
|
2014-04-07 |
2024-06-07 |
中外制药株式会社 |
免疫活化抗原结合分子
|
|
CA2943707A1
(en)
*
|
2014-05-06 |
2015-11-12 |
Genentech, Inc. |
Production of heteromultimeric proteins using mammalian cells
|
|
MX2016014434A
(es)
|
2014-05-13 |
2017-02-23 |
Chugai Pharmaceutical Co Ltd |
Molecula de union a antigeno redirigida a celulas t para celulas que tienen funcion de inmunosupresion.
|
|
US10647777B2
(en)
*
|
2014-05-28 |
2020-05-12 |
Genzyme Corporation |
Methods of controlling the formation of disulfide bonds in protein solutions
|
|
HK1231490A1
(zh)
|
2014-05-28 |
2017-12-22 |
Zymeworks, Inc. |
修饰的抗原结合多肽构建体及其用途
|
|
GB201409558D0
(en)
|
2014-05-29 |
2014-07-16 |
Ucb Biopharma Sprl |
Method
|
|
TWI713453B
(zh)
|
2014-06-23 |
2020-12-21 |
美商健生生物科技公司 |
干擾素α及ω抗體拮抗劑
|
|
JP6822849B2
(ja)
|
2014-06-27 |
2021-01-27 |
イナート・ファルマ・ソシエテ・アノニムＩｎｎａｔｅ Ｐｈａｒｍａ Ｐｈａｒｍａ Ｓ．Ａ． |
多重特異的ＮＫｐ４６結合タンパク質
|
|
CA2952532A1
(en)
|
2014-06-27 |
2015-12-30 |
Innate Pharma |
Multispecific antigen binding proteins
|
|
PL3169706T3
(pl)
|
2014-07-11 |
2020-05-18 |
Genmab A/S |
Przeciwciała wiążące axl
|
|
GB201412659D0
(en)
|
2014-07-16 |
2014-08-27 |
Ucb Biopharma Sprl |
Molecules
|
|
GB201412658D0
(en)
|
2014-07-16 |
2014-08-27 |
Ucb Biopharma Sprl |
Molecules
|
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
KR102612313B1
(ko)
|
2014-07-21 |
2023-12-12 |
노파르티스 아게 |
인간화 항-bcma 키메라 항원 수용체를 사용한 암의 치료
|
|
US9777061B2
(en)
|
2014-07-21 |
2017-10-03 |
Novartis Ag |
Treatment of cancer using a CD33 chimeric antigen receptor
|
|
EP4205749A1
(en)
|
2014-07-31 |
2023-07-05 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing cells
|
|
US10851149B2
(en)
|
2014-08-14 |
2020-12-01 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using GFR α-4 chimeric antigen receptor
|
|
WO2016028896A1
(en)
|
2014-08-19 |
2016-02-25 |
Novartis Ag |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
|
CA2958882A1
(en)
|
2014-09-02 |
2016-03-10 |
Immunogen, Inc. |
Methods for formulating antibody drug conjugate compositions
|
|
CA2959786A1
(en)
*
|
2014-09-03 |
2016-03-10 |
Bioatla, Llc |
Discovering and producing conditionally active biologic proteins in the same eukaryotic cell production hosts
|
|
WO2016036937A1
(en)
|
2014-09-05 |
2016-03-10 |
Janssen Pharmaceutica Nv |
Cd123 binding agents and uses thereof
|
|
SG11201701867SA
(en)
|
2014-09-09 |
2017-04-27 |
Janssen Biotech Inc |
Combination therapies with anti-cd38 antibodies
|
|
PE20170670A1
(es)
|
2014-09-12 |
2017-06-06 |
Genentech Inc |
Anticuerpos anti-cll-1 e inmunoconjugados
|
|
KR102494557B1
(ko)
|
2014-09-17 |
2023-02-02 |
자임워크스 비씨 인코포레이티드 |
세포독성 및 항유사분열성 화합물, 그리고 이를 이용하는 방법
|
|
BR112017005390A2
(pt)
|
2014-09-17 |
2017-12-12 |
Novartis Ag |
células citotóxicas alvo com receptores quiméricos para imunoterapia adotiva
|
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
|
EA201790834A1
(ru)
|
2014-10-14 |
2018-01-31 |
Новартис Аг |
Молекулы антител к pd-l1 и их применение
|
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
|
US11154615B2
(en)
|
2014-11-11 |
2021-10-26 |
Chugai Seiyaku Kabushiki Kaisha |
Library of antigen-binding molecules including modified antibody variable region
|
|
ES2809455T3
(es)
*
|
2014-11-17 |
2021-03-04 |
Regeneron Pharma |
Métodos para tratamiento tumoral usando anticuerpo biespecífico CD3xCD20
|
|
WO2016086189A2
(en)
|
2014-11-26 |
2016-06-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and tumor antigens
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
SG11201704274QA
(en)
|
2014-11-26 |
2017-06-29 |
Xencor Inc |
Heterodimeric antibodies that bind cd3 and cd38
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
PE20171094A1
(es)
|
2014-12-04 |
2017-08-07 |
Janssen Biotech Inc |
Anticuerpos anti-cd38 para el tratamiento de la leucemia linfoblastica aguda
|
|
WO2016091891A1
(en)
|
2014-12-09 |
2016-06-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Human monoclonal antibodies against axl
|
|
US10865253B2
(en)
|
2014-12-19 |
2020-12-15 |
Genmab A/S |
Rodent bispecific heterodimeric proteins
|
|
AR103161A1
(es)
|
2014-12-19 |
2017-04-19 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos antimiostatina y regiones fc variantes así como métodos de uso
|
|
WO2016105450A2
(en)
|
2014-12-22 |
2016-06-30 |
Xencor, Inc. |
Trispecific antibodies
|
|
US10544220B2
(en)
*
|
2015-01-08 |
2020-01-28 |
Genmab A/S |
Bispecific antibodies against CD3 and CD20
|
|
EP3056512A1
(en)
|
2015-02-10 |
2016-08-17 |
Medizinische Universität Wien |
Antibody construct
|
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
|
WO2016159213A1
(ja)
|
2015-04-01 |
2016-10-06 |
中外製薬株式会社 |
ポリペプチド異種多量体の製造方法
|
|
HRP20220893T1
(hr)
|
2015-04-08 |
2022-10-14 |
Novartis Ag |
Cd20 terapije, cd22 terapije, i kombinirane terapije sa stanicom koja eksprimira cd19 kimerni antigenski receptor
|
|
GB201506869D0
(en)
|
2015-04-22 |
2015-06-03 |
Ucb Biopharma Sprl |
Method
|
|
WO2016172583A1
(en)
|
2015-04-23 |
2016-10-27 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
CN116063543A
(zh)
|
2015-04-24 |
2023-05-05 |
豪夫迈·罗氏有限公司 |
多特异性抗原结合蛋白
|
|
EP3291836A4
(en)
|
2015-05-06 |
2018-11-14 |
Janssen Biotech, Inc. |
Prostate specific membrane antigen (psma) bispecific binding agents and uses thereof
|
|
BR112017024877A2
(pt)
|
2015-05-20 |
2019-09-17 |
Janssen Biotech, Inc. |
anticorpo anti-cd38 e seu uso no tratamento de amiloidose de cadeia leve e outras malignidades hematológicas positivas para cd38
|
|
IL255767B2
(en)
|
2015-05-21 |
2024-04-01 |
Alligator Bioscience Ab |
Novel polypeptides
|
|
EP3310814B1
(en)
|
2015-06-16 |
2023-08-02 |
F. Hoffmann-La Roche AG |
Humanized and affinity matured antibodies to fcrh5 and methods of use
|
|
TW201718647A
(zh)
|
2015-06-16 |
2017-06-01 |
建南德克公司 |
抗-cll-1抗體及使用方法
|
|
CN107708734B
(zh)
|
2015-06-22 |
2022-01-11 |
詹森生物科技公司 |
用抗cd38抗体和生存素抑制剂联合治疗血红素恶性肿瘤
|
|
EP3313881A1
(en)
|
2015-06-23 |
2018-05-02 |
Innate Pharma |
Multispecific nk engager proteins
|
|
HRP20240338T1
(hr)
|
2015-06-24 |
2024-05-24 |
Janssen Biotech, Inc. |
Imunomodulacija i liječenje solidnih tumora s protutijelima koja se specifično vežu na cd38
|
|
CN107531788B
(zh)
*
|
2015-06-24 |
2022-06-21 |
豪夫迈·罗氏有限公司 |
对her2和血脑屏障受体特异性的三特异性抗体及使用方法
|
|
SI3313845T1
(sl)
|
2015-06-29 |
2021-01-29 |
Immunogen, Inc. |
Konjugati spremenjenih protiteles cisteina
|
|
US20180201693A1
(en)
|
2015-07-09 |
2018-07-19 |
Genmab A/S |
Bispecific and multispecific antibodies and method for isolation of such
|
|
CN108368171A
(zh)
|
2015-07-10 |
2018-08-03 |
根马布股份公司 |
用于癌症治疗的axl特异性抗体-药物缀合物
|
|
EA201890305A1
(ru)
|
2015-07-15 |
2018-07-31 |
Генмаб А/С |
Гуманизированные или химерные cd3-антитела
|
|
GB201601077D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibody molecule
|
|
GB201601073D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibodies
|
|
GB201601075D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibodies molecules
|
|
CN108025051B
(zh)
|
2015-07-29 |
2021-12-24 |
诺华股份有限公司 |
包含抗pd-1抗体分子的联合疗法
|
|
US20180207273A1
(en)
|
2015-07-29 |
2018-07-26 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
HUE055469T2
(hu)
|
2015-07-29 |
2021-11-29 |
Novartis Ag |
A LAG-3 elleni antitest molekulákat tartalmazó kombinált terápiák
|
|
SMT202100527T1
(it)
|
2015-07-30 |
2021-11-12 |
Macrogenics Inc |
Molecole di legame a pd-1 e lag-3 e loro metodi d'uso
|
|
MA45573A
(fr)
|
2015-08-05 |
2019-05-15 |
Janssen Biotech Inc |
Anticorps anti-cd154 et procédés d'utilisation correspondant
|
|
HRP20201375T1
(hr)
|
2015-08-17 |
2020-11-27 |
Janssen Pharmaceutica Nv |
ANTI-BCMA ANTITIJELA, BISPECIFIČNI ANTIGEN VEŽUĆE MOLEKULE KOJE SE VEŽU ZA BCMA i CD3, I NJIHOVE UPOTREBE
|
|
ES3015389T3
(en)
|
2015-10-08 |
2025-05-05 |
Zymeworks Bc Inc |
Antigen-binding polypeptide constructs comprising kappa and lambda light chains and uses thereof
|
|
KR101851380B1
(ko)
|
2015-10-12 |
2018-04-23 |
아주대학교산학협력단 |
효모접합을 이용한 항체 ch3 도메인 이종이중체 돌연변이쌍 제조 방법 및 이에 의하여 제조된 ch3 돌연변이체 쌍
|
|
WO2017067944A1
(en)
|
2015-10-19 |
2017-04-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of subjects suffering from triple negative breast cancer
|
|
SG11201803675RA
(en)
|
2015-11-02 |
2018-05-30 |
Janssen Pharmaceutica Nv |
Anti-il1rap antibodies, bispecific antigen binding molecules that bind il1rap and cd3, and uses thereof
|
|
ES2912729T3
(es)
|
2015-11-03 |
2022-05-27 |
Janssen Biotech Inc |
Formulaciones subcutáneas de anticuerpos anti-CD38 y sus usos
|
|
PT3370768T
(pt)
|
2015-11-03 |
2022-04-21 |
Janssen Biotech Inc |
Anticorpos que se ligam especificamente ao pd-1 e seus usos
|
|
WO2017086419A1
(ja)
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
液性免疫応答の増強方法
|
|
JP6931329B2
(ja)
|
2015-11-18 |
2021-09-01 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するｔ細胞リダイレクト抗原結合分子を用いた併用療法
|
|
US20190144554A1
(en)
|
2015-12-01 |
2019-05-16 |
Genmab B.V. |
Anti-dr5 antibodies and methods of use thereof
|
|
WO2017096281A1
(en)
*
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Anti-ox40 antibodies and methods of use thereof
|
|
WO2017096276A1
(en)
*
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Anti-gitr antibodies and methods of use thereof
|
|
GB201521383D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl And Ucb Celltech |
Method
|
|
GB201521391D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Antibodies
|
|
GB201521382D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Antibodies
|
|
GB201521393D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Antibodies
|
|
GB201521389D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Method
|
|
CA3007030A1
(en)
|
2015-12-07 |
2017-06-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and psma
|
|
MX2018007089A
(es)
|
2015-12-14 |
2019-01-30 |
Macrogenics Inc |
Moleculas biespecificas que tienen inmunorreactividad con pd-1 y ctla-4, y metodos de uso de las mismas.
|
|
WO2017106684A2
(en)
|
2015-12-17 |
2017-06-22 |
Janssen Biotech, Inc. |
Antibodies specifically binding hla-dr and their uses
|
|
JP2019503349A
(ja)
|
2015-12-17 |
2019-02-07 |
ノバルティス アーゲー |
Ｐｄ−１に対する抗体分子およびその使用
|
|
RU2018125603A
(ru)
|
2015-12-17 |
2020-01-21 |
Новартис Аг |
Комбинация ингибитора с-мет с молекулой антитела к pd-1 и ее применения
|
|
AU2016372934B2
(en)
|
2015-12-18 |
2023-10-05 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies, polypeptides containing variant Fc regions, and methods of use
|
|
MA44140A
(fr)
|
2015-12-22 |
2021-05-19 |
Dana Farber Cancer Inst Inc |
Récepteur d'antigène chimérique (car) contre la mésothéline et anticorps contre l'inhibiteur de pd-l1 pour une utilisation combinée dans une thérapie anticancéreuse
|
|
BR112018009312A8
(pt)
|
2015-12-28 |
2019-02-26 |
Chugai Pharmaceutical Co Ltd |
método para promover eficiência de purificação de polipeptídeo contendo região de fc
|
|
US20210198368A1
(en)
|
2016-01-21 |
2021-07-01 |
Novartis Ag |
Multispecific molecules targeting cll-1
|
|
KR20180100238A
(ko)
|
2016-01-22 |
2018-09-07 |
얀센 바이오테크 인코포레이티드 |
항-ror1 항체, ror1 × cd3 이중특이성 항체, 및 이를 사용하는 방법
|
|
EP3407911B1
(en)
|
2016-01-28 |
2022-05-18 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and pharmaceutical composition for the treatment of cancer
|
|
US20190352423A1
(en)
|
2016-02-05 |
2019-11-21 |
Genmab A/S |
Multispecific antigen-binding molecule with improved internalization characteristics
|
|
CN108699154A
(zh)
|
2016-02-26 |
2018-10-23 |
国家医疗保健研究所 |
对btla具有特异性的抗体及其用途
|
|
AU2017225733A1
(en)
|
2016-03-04 |
2018-09-27 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore
|
|
CA3016424A1
(en)
|
2016-03-14 |
2017-09-21 |
Chugai Seiyaku Kabushiki Kaisha |
Cell injury inducing therapeutic drug for use in cancer therapy
|
|
WO2017162678A1
(en)
|
2016-03-22 |
2017-09-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Humanized anti-claudin-1 antibodies and uses thereof
|
|
WO2017165683A1
(en)
|
2016-03-23 |
2017-09-28 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
|
EP3443096B1
(en)
|
2016-04-15 |
2023-03-01 |
Novartis AG |
Compositions and methods for selective expression of chimeric antigen receptors
|
|
SG10202010156XA
(en)
|
2016-04-20 |
2020-11-27 |
Regeneron Pharma |
Compositions and methods for making antibodies based on use of an expression-enhancing locus
|
|
EP3445781A1
(en)
|
2016-04-20 |
2019-02-27 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for making antibodies based on use of expression-enhancing loci
|
|
CA3016301A1
(en)
|
2016-04-28 |
2017-11-02 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody-containing preparation
|
|
EP3458089A1
(en)
|
2016-05-18 |
2019-03-27 |
Genmab B.V. |
Antibodies and methods of use thereof in treatment of infectious disease
|
|
US20190292259A1
(en)
|
2016-05-24 |
2019-09-26 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and pharmaceutical compositions for the treatment of non small cell lung cancer (nsclc) that coexists with chronic obstructive pulmonary disease (copd)
|
|
US20210177896A1
(en)
|
2016-06-02 |
2021-06-17 |
Novartis Ag |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
CA3026151A1
(en)
|
2016-06-14 |
2017-12-21 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
|
KR102376582B1
(ko)
|
2016-06-17 |
2022-03-18 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체 및 사용 방법
|
|
EP3471750A4
(en)
|
2016-06-21 |
2020-02-26 |
Janssen Biotech, Inc. |
Cysteine engineered fibronectin type iii domain binding molecules
|
|
KR20190020341A
(ko)
|
2016-06-28 |
2019-02-28 |
젠코어 인코포레이티드 |
소마토스타틴 수용체 2에 결합하는 이종이량체 항체
|
|
WO2018002181A1
(en)
|
2016-06-28 |
2018-01-04 |
Umc Utrecht Holding B.V. |
TREATMENT OF IgE-MEDIATED DISEASES WITH ANTIBODIES THAT SPECIFICALLY BIND CD38
|
|
US20190241878A1
(en)
|
2016-07-01 |
2019-08-08 |
Resolve Therapeutics, Llc |
Optimized binuclease fusions and methods
|
|
CN107586336A
(zh)
*
|
2016-07-09 |
2018-01-16 |
复旦大学 |
针对寨卡病毒的全人源单克隆抗体及应用
|
|
KR20240017129A
(ko)
*
|
2016-07-14 |
2024-02-06 |
젠맵 에이/에스 |
Cd40 및 cd137에 대한 다중특이적 항체
|
|
SG11201900344YA
(en)
|
2016-07-15 |
2019-02-27 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
TWI781108B
(zh)
|
2016-07-20 |
2022-10-21 |
比利時商健生藥品公司 |
抗ｇｐｒｃ５ｄ抗體、結合ｇｐｒｃ５ｄ與ｃｄ３之雙特異性抗原結合分子及其用途
|
|
EP3491016A1
(en)
|
2016-07-28 |
2019-06-05 |
Novartis AG |
Combination therapies of chimeric antigen receptors and pd-1 inhibitors
|
|
EP3491022B1
(en)
|
2016-07-29 |
2025-09-10 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Antibodies targeting tumor associated macrophages and uses thereof
|
|
AU2017306267A1
(en)
|
2016-08-01 |
2019-02-14 |
Novartis Ag |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-M2 macrophage molecule
|
|
WO2018026942A1
(en)
*
|
2016-08-02 |
2018-02-08 |
Merrimack Pharmaceuticals, Inc. |
Heteromeric polypeptides
|
|
KR102050463B1
(ko)
|
2016-08-10 |
2019-11-29 |
아주대학교산학협력단 |
항체 중쇄불변부위 이종이중체 (heterodimeric Fc)에 융합된 사이토카인 (heterodimeric Fc-fused cytokine) 및 이를 포함하는 약제학적 조성물
|
|
SG11201900746RA
(en)
|
2016-08-12 |
2019-02-27 |
Janssen Biotech Inc |
Engineered antibodies and other fc-domain containing molecules with enhanced agonism and effector functions
|
|
EP3497126A4
(en)
|
2016-08-12 |
2020-04-08 |
Janssen Biotech, Inc. |
ANTIBODIES OF FC MODIFIED ANTI-TNFR SUPERFAMILY HAVING IMPROVED AGONIST ACTIVITY AND METHODS OF USE THEREOF
|
|
WO2018036947A1
(en)
|
2016-08-22 |
2018-03-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inhibiting biological responses induced by a receptor that uses pi3k to signal in a cell
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
CA3039646A1
(en)
|
2016-10-07 |
2018-04-12 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
PE20240950A1
(es)
|
2016-10-14 |
2024-05-06 |
Xencor Inc |
PROTEINAS DE FUSION FC HETERODIMERICAS IL 15/IL 15R(alfa)
|
|
JOP20190095A1
(ar)
|
2016-10-27 |
2019-04-28 |
Janssen Pharmaceutica Nv |
مركبات ببتيد تيروسين-تيروسين الحلقية كمعدلات لمستقبلات الببتيد العصبي y
|
|
BR112019008702A2
(pt)
|
2016-11-01 |
2019-07-16 |
Genmab B.V. |
polipeptídeo, método de diminuição de uma função fc efetora de um polipeptídeo, composição, método de tratamento, kit de partes, e, uso de um polipeptídeo ou composição.
|
|
JP7784795B2
(ja)
|
2016-11-15 |
2025-12-12 |
ジェネンテック， インコーポレイテッド |
抗ｃｄ２０／抗ｃｄ３二重特異性抗体による処置のための投与
|
|
GB201619652D0
(en)
|
2016-11-21 |
2017-01-04 |
Alligator Bioscience Ab |
Novel polypeptides
|
|
MA46887A
(fr)
|
2016-11-23 |
2019-10-02 |
Immunogen Inc |
Sulfonation sélective de dérivés de benzodiazépine
|
|
US10597438B2
(en)
|
2016-12-14 |
2020-03-24 |
Janssen Biotech, Inc. |
PD-L1 binding fibronectin type III domains
|
|
EP3932432A1
(en)
|
2016-12-14 |
2022-01-05 |
Janssen Biotech, Inc. |
Cd8a-binding fibronectin type iii domains
|
|
WO2018111978A1
(en)
|
2016-12-14 |
2018-06-21 |
Janssen Biotech, Inc. |
Cd137 binding fibronectin type iii domains
|
|
EP4043485A1
(en)
|
2017-01-26 |
2022-08-17 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
KR20250089564A
(ko)
|
2017-02-08 |
2025-06-18 |
드래곤플라이 쎄라퓨틱스, 인크. |
천연 킬러 세포의 활성화를 위한 다중-특이적 결합 단백질 및 암 치료에서의 그의 치료적 용도
|
|
MX2019009346A
(es)
|
2017-02-10 |
2019-10-02 |
Genmab Bv |
Variantes de polipeptidos y usos de los mismos.
|
|
CN110997714B
(zh)
|
2017-02-17 |
2024-05-03 |
赛诺菲 |
对肌营养不良蛋白聚糖和层粘连蛋白-2具有特异性的多特异性结合分子
|
|
WO2018151841A1
(en)
|
2017-02-17 |
2018-08-23 |
Sanofi |
Multispecific binding molecules having specificity to dystroglycan and laminin-2
|
|
JP7304288B2
(ja)
|
2017-02-17 |
2023-07-06 |
サノフイ |
ジストログリカンおよびラミニン２に対する特異性を有する多特異性結合性分子
|
|
MY205898A
(en)
|
2017-02-17 |
2024-11-19 |
Denali Therapeutics Inc |
Engineered transferrin receptor binding polypeptides
|
|
KR20190120782A
(ko)
|
2017-02-20 |
2019-10-24 |
드래곤플라이 쎄라퓨틱스, 인크. |
Her2, nkg2d 및 cd16에 결합하는 단백질
|
|
CN110392697A
(zh)
|
2017-03-02 |
2019-10-29 |
国家医疗保健研究所 |
对nectin-4具有特异性的抗体及其用途
|
|
CN118063619A
(zh)
|
2017-03-02 |
2024-05-24 |
诺华股份有限公司 |
工程化的异源二聚体蛋白质
|
|
PL3592769T3
(pl)
|
2017-03-09 |
2024-10-14 |
Genmab A/S |
Przeciwciała przeciwko PD-L1
|
|
IL269645B2
(en)
|
2017-03-31 |
2025-05-01 |
Genmab Holding B V |
Bispecific anti-cd37 antibodies, monoclonal anti-cd37 antibodies and methods of use thereof
|
|
JP2020515637A
(ja)
|
2017-04-03 |
2020-05-28 |
オンコロジー、インコーポレイテッド |
免疫腫瘍剤を伴うｐｓ標的化抗体を用いる癌の治療方法
|
|
WO2018189403A1
(en)
|
2017-04-14 |
2018-10-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of cancer
|
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
EP3615068A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
MX2019012953A
(es)
|
2017-05-02 |
2020-02-12 |
Alligator Bioscience Ab |
Anticuerpo biespecifico contra ox40 y ctla-4.
|
|
KR20240056666A
(ko)
|
2017-06-05 |
2024-04-30 |
얀센 바이오테크 인코포레이티드 |
이중특이성 항체 생성을 위한 표면 전하 조작 방법
|
|
JP7235733B2
(ja)
|
2017-06-05 |
2023-03-08 |
ヤンセン バイオテツク，インコーポレーテツド |
Ｐｄ－１に特異的に結合する抗体、及び使用方法
|
|
JP2020522543A
(ja)
|
2017-06-07 |
2020-07-30 |
ゲンマブ ビー．ブイ． |
変異ＩｇＧ六量体に基づく治療用抗体
|
|
UY37758A
(es)
|
2017-06-12 |
2019-01-31 |
Novartis Ag |
Método de fabricación de anticuerpos biespecíficos, anticuerpos biespecíficos y uso terapéutico de dichos anticuerpos
|
|
CA3068270A1
(en)
|
2017-06-21 |
2018-12-27 |
Gsbio, Llc |
Heterodimeric bispecific antibodies
|
|
CA3065328C
(en)
|
2017-06-21 |
2023-08-15 |
Gilead Sciences, Inc. |
Multispecific antibodies that target hiv gp120 and cd3
|
|
MX2019015885A
(es)
|
2017-06-22 |
2020-09-10 |
Novartis Ag |
Moleculas de anticuerpo que se unen a cd73 y usos de las mismas.
|
|
KR20200022447A
(ko)
|
2017-06-27 |
2020-03-03 |
노파르티스 아게 |
항-tim-3 항체의 투여 요법 및 그의 용도
|
|
AU2018291497A1
(en)
|
2017-06-30 |
2020-01-16 |
Xencor, Inc. |
Targeted heterodimeric Fc fusion proteins containing IL-15/IL-15Ra and antigen binding domains
|
|
WO2019010224A1
(en)
|
2017-07-03 |
2019-01-10 |
Torque Therapeutics, Inc. |
FUSION MOLECULES TARGETING IMMUNE REGULATORY CELLS AND USES THEREOF
|
|
PE20200757A1
(es)
|
2017-07-11 |
2020-07-27 |
Compass Therapeutics Llc |
Anticuerpos agonistas que se unen a cd137 humano y sus usos
|
|
WO2019018730A1
(en)
|
2017-07-20 |
2019-01-24 |
Novartis Ag |
DOSAGE REGIMES FOR ANTI-LAG3 ANTIBODIES AND USES THEREOF
|
|
WO2019014912A1
(zh)
*
|
2017-07-21 |
2019-01-24 |
赵磊 |
一种异二聚体蛋白及其制备方法
|
|
KR20250020679A
(ko)
|
2017-08-04 |
2025-02-11 |
젠맵 에이/에스 |
Pd-l1 및 cd137에 결합하는 결합제 및 그의 용도
|
|
US10891219B1
(en)
|
2017-08-07 |
2021-01-12 |
Electronic Arts Inc. |
Code failure prediction system
|
|
CN111315767B
(zh)
|
2017-08-22 |
2025-03-18 |
萨纳生物有限责任公司 |
可溶性干扰素受体及其用途
|
|
EP3457139A1
(en)
|
2017-09-19 |
2019-03-20 |
Promise Advanced Proteomics |
Antibody-like peptides for quantifying therapeutic antibodies
|
|
CA3074933A1
(en)
|
2017-09-21 |
2019-03-28 |
Imcheck Therapeutics Sas |
Antibodies having specificity for btn2 and uses thereof
|
|
KR20200067197A
(ko)
|
2017-10-20 |
2020-06-11 |
에프. 호프만-라 로슈 아게 |
단일특이적 항체로부터 다중특이적 항체의 생성 방법
|
|
CN111372947B
(zh)
|
2017-10-30 |
2025-08-15 |
豪夫迈·罗氏有限公司 |
在体内从单特异性抗体产生多特异性抗体的方法
|
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
|
SG11202003833TA
(en)
|
2017-11-01 |
2020-05-28 |
Chugai Pharmaceutical Co Ltd |
Antibody variant and isoform with lowered biological activity
|
|
US11312770B2
(en)
|
2017-11-08 |
2022-04-26 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
US20200277378A1
(en)
|
2017-11-16 |
2020-09-03 |
Novartis Ag |
Combination therapies
|
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
CA3079363A1
(en)
*
|
2017-11-21 |
2019-05-31 |
Innate Pharma |
Multispecific antigen binding proteins
|
|
WO2019106126A1
(en)
|
2017-12-01 |
2019-06-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Mdm2 modulators for the diagnosis and treatment of liposarcoma
|
|
EP3498293A1
(en)
|
2017-12-15 |
2019-06-19 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Treatment of monogenic diseases with an anti-cd45rc antibody
|
|
WO2019125732A1
(en)
|
2017-12-19 |
2019-06-27 |
Xencor, Inc. |
Engineered il-2 fc fusion proteins
|
|
CN115925882A
(zh)
|
2017-12-22 |
2023-04-07 |
瑞泽恩制药公司 |
用于表征药物产品杂质的系统和方法
|
|
EP3732195A4
(en)
|
2017-12-28 |
2022-02-09 |
Chugai Seiyaku Kabushiki Kaisha |
CYTOTOXICITY-INDUCING THERAPEUTIC
|
|
EP3737692A4
(en)
|
2018-01-09 |
2021-09-29 |
Elstar Therapeutics, Inc. |
CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
|
|
CN111801580B
(zh)
|
2018-01-12 |
2024-08-23 |
建新公司 |
用于定量多肽的方法
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
JP2021510740A
(ja)
|
2018-01-24 |
2021-04-30 |
ゲンマブ ビー．ブイ． |
ポリペプチド変種およびそれらの用途
|
|
EP3746116A1
(en)
|
2018-01-31 |
2020-12-09 |
Novartis AG |
Combination therapy using a chimeric antigen receptor
|
|
PE20210375A1
(es)
|
2018-02-08 |
2021-03-02 |
Dragonfly Therapeutics Inc |
Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales
|
|
CA3090244A1
(en)
|
2018-02-08 |
2019-08-15 |
Dragonfly Therapeutics, Inc. |
Antibody variable domains targeting the nkg2d receptor
|
|
SG11202007390YA
(en)
|
2018-02-08 |
2020-08-28 |
Genentech Inc |
Bispecific antigen-binding molecules and methods of use
|
|
EP3749360A1
(en)
|
2018-02-09 |
2020-12-16 |
Genmab A/S |
Pharmaceutical compositions comprising bispecific antibodies directed against cd3 and cd20 and their uses
|
|
CN112119093A
(zh)
|
2018-02-20 |
2020-12-22 |
蜻蜓治疗公司 |
结合cd33、nkg2d和cd16的多特异性结合蛋白和使用方法
|
|
JP2018138022A
(ja)
*
|
2018-02-23 |
2018-09-06 |
ゲンマブ ビー．ブイ． |
ヒトＩｇＧ１ Ｆｃ領域変異体およびその使用
|
|
CN120795158A
(zh)
|
2018-03-12 |
2025-10-17 |
健玛保 |
抗体
|
|
WO2019175368A1
(en)
|
2018-03-14 |
2019-09-19 |
Affimed Gmbh |
Bispecific egfr/cd16 antigen-binding protein
|
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
WO2019195623A2
(en)
|
2018-04-04 |
2019-10-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
|
JP2021521445A
(ja)
|
2018-04-13 |
2021-08-26 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
前立腺癌又は乳癌を患っている患者の転帰を予測するための及び処置のための方法
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
CN112867734A
(zh)
|
2018-04-18 |
2021-05-28 |
Xencor股份有限公司 |
包含IL-15/IL-15Ra Fc融合蛋白和PD-1抗原结合结构域的靶向PD-1的异源二聚体融合蛋白及其用途
|
|
IL278090B2
(en)
|
2018-04-18 |
2024-07-01 |
Xencor Inc |
Il-15/il-15rα heterodimeric fc fusion proteins and uses thereof
|
|
US11505595B2
(en)
|
2018-04-18 |
2022-11-22 |
Xencor, Inc. |
TIM-3 targeted heterodimeric fusion proteins containing IL-15/IL-15RA Fc-fusion proteins and TIM-3 antigen binding domains
|
|
WO2019207030A1
(en)
|
2018-04-26 |
2019-10-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting a response with an immune checkpoint inhibitor in a patient suffering from a lung cancer
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
BR112020022179A2
(pt)
|
2018-05-03 |
2021-02-02 |
Genmab B.V. |
primeiro anticorpo, anticorpo, composição, métodos para tratar um indivíduo tendo uma doença, para esgotar uma população de célula e para induzir a proliferação em uma população de célula, e, kit.
|
|
EP3793606A4
(en)
|
2018-05-16 |
2022-08-31 |
Janssen Biotech, Inc. |
METHODS OF TREATMENT OF CANCER AND ENHANCEMENT OF THE EFFECTIVENESS OF T-CELL REFERRING THERAPEUTICS
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
CN112384534A
(zh)
|
2018-05-21 |
2021-02-19 |
指南针制药有限责任公司 |
用于增强nk细胞对靶细胞的杀死的组合物和方法
|
|
JOP20190116A1
(ar)
|
2018-05-24 |
2019-11-24 |
Janssen Biotech Inc |
الأجسام المضادة لتكتل التمايز 33 (cd33)، والأجسام المضادة ثنائية النوعية لتكتل التمايز 33 (cd33)/تكتل التمايز 3 (cd3) واستخداماتها
|
|
CN112703203B
(zh)
|
2018-05-24 |
2025-02-25 |
詹森生物科技公司 |
单特异性和多特异性抗-tmeff2抗体及其用途
|
|
EP3802609A2
(en)
|
2018-05-24 |
2021-04-14 |
Janssen Biotech, Inc. |
Psma binding agents and uses thereof
|
|
DK3802608T3
(da)
|
2018-05-24 |
2025-06-10 |
Janssen Biotech Inc |
Anti-cd3-antistoffer og anvendelser deraf
|
|
WO2019227003A1
(en)
|
2018-05-25 |
2019-11-28 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
CN112384531B
(zh)
|
2018-06-01 |
2024-05-14 |
诺华股份有限公司 |
针对bcma的结合分子及其用途
|
|
BR112020024249A2
(pt)
|
2018-06-01 |
2021-03-02 |
Compugen Ltd. |
anticorpo biespecífico anti-pvrig/anti-tigit, composição, composição de ácido nucleico, composição de vetor de expressão, célula hospedeira, métodos para produzir um anticorpo biespecífico anti-pvrig/anti-tigit, para ativação de células t de um paciente, para ativação de células t citotóxicas de um paciente, para ativação de células nk de um paciente, para ativação de células t gama delta de um paciente, para ativação de células th1 de um paciente, para diminuir ou eliminar o número de células e/ou a atividade de pelo menos uma das células t reguladoras em um paciente, para aumentar a produção de interferon-gama e/ou a secreção de citocinas pró-inflamatórias em um paciente e para tratamento de câncer em um paciente, anticorpo anti-pvrig, anticorpo anti-tigit, e, vetor de expressão.
|
|
EP3806962A1
(en)
|
2018-06-13 |
2021-04-21 |
Novartis AG |
Bcma chimeric antigen receptors and uses thereof
|
|
MA52969A
(fr)
|
2018-06-19 |
2021-04-28 |
Atarga Llc |
Molécules d'anticorps se liant au composant du complément 5 et leurs utilisations
|
|
US12275797B2
(en)
|
2018-06-22 |
2025-04-15 |
Genmab Holding B.V. |
Anti-CD37 antibodies and anti-CD20 antibodies, compositions and methods of use thereof
|
|
US12247065B2
(en)
|
2018-06-22 |
2025-03-11 |
Genmab A/S |
Method for producing a controlled mixture of two or more different antibodies
|
|
AU2019297451A1
(en)
|
2018-07-03 |
2021-01-28 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
SG11202012993SA
(en)
|
2018-07-13 |
2021-02-25 |
Genmab As |
Variants of cd38 antibody and uses thereof
|
|
EP3820890A1
(en)
|
2018-07-13 |
2021-05-19 |
Genmab A/S |
Trogocytosis-mediated therapy using cd38 antibodies
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
EA202091888A1
(ru)
|
2018-08-08 |
2020-10-23 |
Драгонфлай Терапьютикс, Инк. |
Вариабельные домены антител, нацеленные на рецептор nkg2d
|
|
BR112021002276A2
(pt)
|
2018-08-08 |
2021-05-04 |
Dragonfly Therapeutics, Inc. |
proteínas de ligação a nkg2d, cd16 e um antígeno associado ao tumor
|
|
CA3108427A1
(en)
|
2018-08-08 |
2020-02-13 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use
|
|
EP3856778A1
(en)
|
2018-09-24 |
2021-08-04 |
The Medical College of Wisconsin, Inc. |
System and method for the development of cd30 bispecific antibodies for immunotherapy of cd30+ malignancies
|
|
WO2020067541A1
(ja)
*
|
2018-09-28 |
2020-04-02 |
協和キリン株式会社 |
抗体組成物
|
|
WO2020070062A1
(en)
|
2018-10-01 |
2020-04-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of tim-3 inhibitors for the treatment of exacerbations in patients suffering from severe asthma
|
|
EP3861016A2
(en)
|
2018-10-03 |
2021-08-11 |
Xencor, Inc. |
Il-12 heterodimeric fc-fusion proteins
|
|
WO2020070313A1
(en)
|
2018-10-04 |
2020-04-09 |
Genmab Holding B.V. |
Pharmaceutical compositions comprising bispecific anti-cd37 antibodies
|
|
MA53862A
(fr)
|
2018-10-12 |
2022-01-19 |
Xencor Inc |
Protéines de fusion fc d'il-15/il-15ralpha ciblant pd-1 et utilisations dans des polythérapies faisant intervenir celles-ci
|
|
CA3117212A1
(en)
|
2018-10-23 |
2020-04-30 |
Dragonfly Therapeutics, Inc. |
Heterodimeric fc-fused proteins
|
|
WO2020094609A1
(en)
|
2018-11-06 |
2020-05-14 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of acute myeloid leukemia by eradicating leukemic stem cells
|
|
WO2020094744A1
(en)
|
2018-11-06 |
2020-05-14 |
Genmab A/S |
Antibody formulation
|
|
AU2019379576A1
(en)
|
2018-11-13 |
2021-06-03 |
Compass Therapeutics Llc |
Multispecific binding constructs against checkpoint molecules and uses thereof
|
|
TWI874341B
(zh)
|
2018-12-18 |
2025-03-01 |
美商健生生物科技公司 |
產生異二聚體抗體之方法
|
|
EP3897853A1
(en)
|
2018-12-20 |
2021-10-27 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
|
MX2021007391A
(es)
|
2018-12-20 |
2021-09-23 |
Novartis Ag |
Regimenes de baja dosis extendida para inhibidores de mdm2.
|
|
WO2020128972A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
MX2021007677A
(es)
|
2018-12-24 |
2021-12-10 |
Sanofi Sa |
Proteinas de union multiespecificas basadas en pseudofab.
|
|
CN113574386A
(zh)
|
2019-01-03 |
2021-10-29 |
国家医疗保健研究所 |
用于增强癌症患者的cd8+t细胞依赖性免疫应答的方法和药物组合物
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
WO2020148651A1
(en)
|
2019-01-15 |
2020-07-23 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions and methods for the treatment of juvenile idiopathic arthritis
|
|
WO2020148677A1
(en)
|
2019-01-18 |
2020-07-23 |
Janssen Biotech, Inc. |
Gprc5d chimeric antigen receptors and cells expressing the same
|
|
MA54814A
(fr)
|
2019-01-23 |
2021-12-01 |
Janssen Biotech Inc |
Compositions d'anticorps anti-tnf destinées à être utilisées dans des méthodes de traitement d'arthrite psoriasique
|
|
ES2982474T3
(es)
|
2019-02-15 |
2024-10-16 |
Novartis Ag |
Derivados de 3-(1-oxoisoindolin-2-il)piperidin-1,6-diona sustituidos y usos de estos
|
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
|
JP7483732B2
(ja)
|
2019-02-15 |
2024-05-15 |
ノバルティス アーゲー |
３－（１－オキソ－５－（ピペリジン－４－イル）イソインドリン－２－イル）ピペリジン－２，６－ジオン誘導体及びその使用
|
|
CA3130754A1
(en)
|
2019-02-21 |
2020-08-27 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to t cell related cancer cells and uses thereof
|
|
WO2020172605A1
(en)
|
2019-02-21 |
2020-08-27 |
Elstar Therapeutics, Inc. |
Antibody molecules that bind to nkp30 and uses thereof
|
|
WO2020172553A1
(en)
|
2019-02-22 |
2020-08-27 |
Novartis Ag |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
WO2020174370A2
(en)
|
2019-02-26 |
2020-09-03 |
Janssen Biotech, Inc. |
Combination therapies and patient stratification with bispecific anti-egfr/c-met antibodies
|
|
AU2020232605A1
(en)
|
2019-03-01 |
2021-10-21 |
Xencor, Inc. |
Heterodimeric antibodies that bind ENPP3 and CD3
|
|
CN113874400B
(zh)
|
2019-03-11 |
2025-02-07 |
詹森生物科技公司 |
抗Vβ17/抗CD123双特异性抗体
|
|
WO2020183418A1
(en)
|
2019-03-14 |
2020-09-17 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-il12/il23 antibody compositions
|
|
JP7635137B2
(ja)
|
2019-03-14 |
2025-02-25 |
ヤンセン バイオテツク，インコーポレーテツド |
抗ｔｎｆ抗体組成物を産生するための方法
|
|
EA202192508A1
(ru)
|
2019-03-14 |
2022-03-29 |
Янссен Байотек, Инк. |
Способы получения композиций антитела к фно
|
|
KR20210142002A
(ko)
|
2019-03-14 |
2021-11-23 |
얀센 바이오테크 인코포레이티드 |
항-tnf 항체 조성물을 생성하기 위한 제조 방법
|
|
US12258400B2
(en)
|
2019-03-20 |
2025-03-25 |
Imcheck Therapeutics Sas |
Antibodies having specificity for BTN2 and uses thereof
|
|
SG11202110732XA
(en)
|
2019-03-29 |
2021-10-28 |
Atarga Llc |
Anti fgf23 antibody
|
|
MA55717A
(fr)
|
2019-04-19 |
2022-02-23 |
Janssen Biotech Inc |
Méthodes de traitement du cancer de la prostate avec un anticorps anti-psma/cd3
|
|
US11667712B2
(en)
|
2019-05-08 |
2023-06-06 |
Janssen Biotech, Inc. |
Materials and methods for modulating t cell mediated immunity
|
|
US20220315661A1
(en)
|
2019-05-09 |
2022-10-06 |
Genmab B.V. |
Dosage regimens for a combination of anti-dr5 antibodies for use in treating cancer
|
|
EP3968985A4
(en)
*
|
2019-05-14 |
2023-07-26 |
Janssen Biotech, Inc. |
Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors
|
|
US11879013B2
(en)
|
2019-05-14 |
2024-01-23 |
Janssen Biotech, Inc. |
Combination therapies with bispecific anti-EGFR/c-Met antibodies and third generation EGFR tyrosine kinase inhibitors
|
|
JOP20210309A1
(ar)
|
2019-05-21 |
2023-01-30 |
Novartis Ag |
جزيئات ربط بـ cd19 واستخدامتها
|
|
US12037378B2
(en)
|
2019-05-21 |
2024-07-16 |
Novartis Ag |
Variant CD58 domains and uses thereof
|
|
US20220396631A1
(en)
|
2019-05-21 |
2022-12-15 |
Lu HUANG |
Trispecific binding molecules against bcma and uses thereof
|
|
US20220235148A1
(en)
|
2019-05-30 |
2022-07-28 |
Amgen Inc. |
Engineering the hinge region to drive antibody dimerization
|
|
JP2022536279A
(ja)
|
2019-06-03 |
2022-08-15 |
ヤンセン バイオテツク，インコーポレーテツド |
乾癬性関節炎を治療するための抗ｔｎｆ抗体組成物及び方法
|
|
TW202112808A
(zh)
|
2019-06-05 |
2021-04-01 |
日商中外製藥股份有限公司 |
抗體切斷部位結合分子
|
|
US20230057904A1
(en)
|
2019-07-10 |
2023-02-23 |
Chugai Seiyaku Kabushiki Kaisha |
Claudin-6 binding molecules and uses thereof
|
|
JP2022540843A
(ja)
|
2019-07-12 |
2022-09-20 |
ヤンセン ファーマシューティカ エヌ．ベー． |
結合剤及びその使用
|
|
US12319745B2
(en)
|
2019-07-16 |
2025-06-03 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Antibodies having specificity for CD38 and uses thereof
|
|
NZ785553A
(en)
|
2019-07-26 |
2025-07-25 |
Janssen Biotech Inc |
Proteins comprising kallikrein related peptidase 2 antigen binding domains and their uses
|
|
AU2020329217A1
(en)
|
2019-08-12 |
2022-07-28 |
Aptevo Research And Development Llc |
4-1BB and OX40 binding proteins and related compositions and methods, antibodies against 4-1BB, antibodies against OX40
|
|
MX2022001721A
(es)
|
2019-08-15 |
2022-03-11 |
Genmab As |
Composiciones farmaceuticas que comprenden anticuerpos biespecificos dirigidos contra cd3 y cd20 y sus usos.
|
|
KR20220062494A
(ko)
|
2019-08-15 |
2022-05-17 |
얀센 바이오테크 인코포레이티드 |
개선된 단일 사슬 가변 단편을 위한 재료 및 방법
|
|
US20230257479A1
(en)
|
2019-09-12 |
2023-08-17 |
Genmab A/S |
Bispecific antibodies binding to 5t4 and cd3 for use in treatment of cancer
|
|
WO2021058729A1
(en)
|
2019-09-27 |
2021-04-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-müllerian inhibiting substance type i receptor antibodies and uses thereof
|
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
|
US11781138B2
(en)
|
2019-10-14 |
2023-10-10 |
Aro Biotherapeutics Company |
FN3 domain-siRNA conjugates and uses thereof
|
|
US12491255B2
(en)
|
2019-10-14 |
2025-12-09 |
Aro Biotherapeutics Company |
EPCAM binding fibronectin type III domains
|
|
CN119119240A
(zh)
|
2019-10-14 |
2024-12-13 |
Aro生物疗法公司 |
结合cd71的纤维粘连蛋白iii型结构域
|
|
KR20220087498A
(ko)
|
2019-10-21 |
2022-06-24 |
노파르티스 아게 |
Tim-3 억제제 및 그의 용도
|
|
IL292347A
(en)
|
2019-10-21 |
2022-06-01 |
Novartis Ag |
Combination treatments with ventoclax and tim-3 inhibitors
|
|
JP2023500701A
(ja)
|
2019-11-06 |
2023-01-10 |
ジェンマブ ビー．ブイ． |
抗体変種の組み合わせおよびその使用
|
|
JP2023502652A
(ja)
|
2019-11-18 |
2023-01-25 |
ヤンセン バイオテツク，インコーポレーテツド |
抗ｃｄ７９キメラ抗原受容体、ｃａｒ－ｔ細胞、及びそれらの使用
|
|
IL293215A
(en)
|
2019-11-26 |
2022-07-01 |
Novartis Ag |
Chimeric antigen receptors that bind bcma and cd19 and their uses
|
|
US20230040928A1
(en)
|
2019-12-09 |
2023-02-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies having specificity to her4 and uses thereof
|
|
US20210188990A1
(en)
|
2019-12-11 |
2021-06-24 |
Cilag Gmbh International |
Multispecific binding molecules comprising ltbr and edb binding domains and uses thereof
|
|
AU2020403145B2
(en)
|
2019-12-13 |
2025-06-26 |
Genentech, Inc. |
Anti-Ly6G6D antibodies and methods of use
|
|
GB201919061D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Multi-specific antibody
|
|
JP2023507190A
(ja)
|
2019-12-20 |
2023-02-21 |
ノバルティス アーゲー |
増殖性疾患を治療するための抗ＴＧＦβ抗体及びチェックポイント阻害薬の使用
|
|
GB201919062D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Antibody
|
|
KR102645629B1
(ko)
|
2019-12-27 |
2024-03-07 |
추가이 세이야쿠 가부시키가이샤 |
항ctla-4 항체 및 그의 사용
|
|
GB2609554B
(en)
|
2020-01-03 |
2025-08-20 |
Marengo Therapeutics Inc |
Anti-TCR antibody molecules and uses thereof
|
|
PE20230113A1
(es)
|
2020-01-16 |
2023-01-27 |
Genmab As |
Formulaciones de anticuerpos anti-cd38 y usos de las mismas
|
|
CN114980902A
(zh)
|
2020-01-17 |
2022-08-30 |
诺华股份有限公司 |
用于治疗骨髓增生异常综合征或慢性粒单核细胞白血病的包含tim-3抑制剂和低甲基化药物的组合
|
|
CN111239406B
(zh)
*
|
2020-01-17 |
2023-06-30 |
王兰珍 |
一种肝细胞生长因子胶乳免疫比浊检测试剂盒及其应用
|
|
EP4090762A1
(en)
|
2020-01-17 |
2022-11-23 |
Becton, Dickinson and Company |
Methods and compositions for single cell secretomics
|
|
WO2021154839A1
(en)
|
2020-01-30 |
2021-08-05 |
Umoja Biopharma, Inc. |
Bispecific transduction enhancer
|
|
GB202001447D0
(en)
|
2020-02-03 |
2020-03-18 |
Ucb Biopharma Sprl |
Antibodies
|
|
WO2021155916A1
(en)
|
2020-02-04 |
2021-08-12 |
BioNTech SE |
Treatment involving antigen vaccination and binding agents binding to pd-l1 and cd137
|
|
WO2021156326A1
(en)
|
2020-02-04 |
2021-08-12 |
Genmab A/S |
Antibodies for use in therapy
|
|
JOP20220184A1
(ar)
|
2020-02-12 |
2023-01-30 |
Janssen Biotech Inc |
علاج مصابي السرطان ممن لديهم طفرات تخطي c-Met إكسون14
|
|
TW202144389A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在多發性骨髓瘤中表現之新抗原及其用途
|
|
TW202144388A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
|
ES3007624T3
(en)
|
2020-02-21 |
2025-03-20 |
Genmab Bv |
Methods for the quantification of glycoproteins
|
|
KR20220147109A
(ko)
|
2020-02-27 |
2022-11-02 |
노파르티스 아게 |
키메라 항원 수용체 발현 세포의 제조 방법
|
|
BR112022016491A2
(pt)
|
2020-02-28 |
2022-10-11 |
Shanghai Henlius Biotech Inc |
Construto anti-cd137 e usos do mesmo
|
|
KR20220145859A
(ko)
|
2020-02-28 |
2022-10-31 |
상하이 헨리우스 바이오테크, 인크. |
항cd137 작제물, 다중 특이적 항체 및 그 용도
|
|
WO2021175954A1
(en)
|
2020-03-04 |
2021-09-10 |
Imcheck Therapeutics Sas |
Antibodies having specificity for btnl8 and uses thereof
|
|
WO2021178896A1
(en)
|
2020-03-06 |
2021-09-10 |
Go Therapeutics, Inc. |
Anti-glyco-cd44 antibodies and their uses
|
|
PE20240020A1
(es)
|
2020-03-13 |
2024-01-04 |
Janssen Biotech Inc |
Materiales y metodos para la union de siglec-3/cd33
|
|
AU2021236906A1
(en)
|
2020-03-18 |
2022-08-18 |
Genmab A/S |
Antibodies binding to B7H4
|
|
JP2023520773A
(ja)
|
2020-03-27 |
2023-05-19 |
ノバルティス アーゲー |
増殖性疾患及び自己免疫疾患を治療するための二重特異性組合せ治療
|
|
US11179644B2
(en)
|
2020-03-30 |
2021-11-23 |
Electronic Arts Inc. |
Videogame telemetry data and game asset tracker for session recordings
|
|
IL296514A
(en)
|
2020-03-30 |
2022-11-01 |
Univ Mie |
Bispecific antibody
|
|
KR20220161375A
(ko)
|
2020-03-31 |
2022-12-06 |
추가이 세이야쿠 가부시키가이샤 |
다중 특이성 항원 결합 분자를 제조하기 위한 방법
|
|
EP4135841A1
(en)
|
2020-04-15 |
2023-02-22 |
Voyager Therapeutics, Inc. |
Tau binding compounds
|
|
EP4136121B1
(en)
|
2020-04-16 |
2025-05-28 |
Janssen Biotech, Inc. |
Systems, materials, and methods for reversed-phase high performance liquid chromatography (rp-hplc) for monitoring formation of multi-specific molecules
|
|
EP4143234A4
(en)
|
2020-04-26 |
2024-07-17 |
Biocytogen Pharmaceuticals (Beijing) Co., Ltd. |
Modified immunoglobulins
|
|
US12157771B2
(en)
|
2020-05-06 |
2024-12-03 |
Dragonfly Therapeutics, Inc. |
Proteins binding NKG2D, CD16 and CLEC12A
|
|
JP2023524149A
(ja)
|
2020-05-08 |
2023-06-08 |
ジェンマブ エー／エス |
Ｃｄ３およびｃｄ２０に対する二重特異性抗体
|
|
US11446570B2
(en)
|
2020-05-08 |
2022-09-20 |
Electronic Arts Inc. |
Automated test multiplexing system
|
|
AU2021272291A1
(en)
|
2020-05-11 |
2023-02-02 |
Janssen Biotech, Inc. |
Methods for treating multiple myeloma
|
|
US20230181753A1
(en)
|
2020-05-12 |
2023-06-15 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
New method to treat cutaneous t-cell lymphomas and tfh derived lymphomas
|
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
|
WO2021228167A1
(zh)
*
|
2020-05-15 |
2021-11-18 |
神州细胞工程有限公司 |
通过形成Fc片段融合蛋白糖缀合物增强抗原免疫原性的方法
|
|
US12066883B2
(en)
|
2020-05-19 |
2024-08-20 |
Electronic Arts Inc. |
Glitch detection system
|
|
JP7048665B2
(ja)
*
|
2020-05-22 |
2022-04-05 |
ゲンマブ ビー．ブイ． |
ヒトＩｇＧ１ Ｆｃ領域変異体およびその使用
|
|
PE20230389A1
(es)
|
2020-05-27 |
2023-03-06 |
Janssen Biotech Inc |
Proteinas que comprenden dominios de union al antigeno de cd3 y usos de estas
|
|
GB202008860D0
(en)
|
2020-06-11 |
2020-07-29 |
Univ Oxford Innovation Ltd |
BTLA antibodies
|
|
US20230321067A1
(en)
|
2020-06-23 |
2023-10-12 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
TW202216761A
(zh)
|
2020-07-16 |
2022-05-01 |
瑞士商諾華公司 |
抗β細胞素抗體、其片段及多特異性結合分子
|
|
EP4185388A1
(en)
|
2020-07-23 |
2023-05-31 |
Genmab B.V. |
A combination of anti-dr5 antibodies and an immunomodulatory imide drug for use in treating multiple myeloma
|
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
|
WO2022024024A2
(en)
|
2020-07-29 |
2022-02-03 |
Janssen Biotech, Inc. |
Proteins comprising hla-g antigen binding domains and their uses
|
|
CA3190649A1
(en)
|
2020-07-31 |
2022-02-03 |
Chugai Seiyaku Kabushiki Kaisha |
Pharmaceutical composition comprising cell expressing chimeric receptor
|
|
CN116322776A
(zh)
|
2020-08-03 |
2023-06-23 |
詹森生物科技公司 |
用于病毒治疗剂中的多向生物转运的材料和方法
|
|
EP4188549A1
(en)
|
2020-08-03 |
2023-06-07 |
Novartis AG |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US20230287088A1
(en)
|
2020-08-06 |
2023-09-14 |
BioNTech SE |
Binding agents for coronavirus s protein
|
|
KR20230062833A
(ko)
|
2020-08-10 |
2023-05-09 |
얀센 바이오테크 인코포레이티드 |
생물공학적 바이러스 특이적 림프구 생산을 위한 재료 및 방법
|
|
KR20230166150A
(ko)
|
2020-08-19 |
2023-12-06 |
젠코어 인코포레이티드 |
항-cd28 조성물
|
|
WO2022040466A1
(en)
|
2020-08-20 |
2022-02-24 |
Amgen Inc. |
Antigen binding proteins with non-canonical disulfide in fab region
|
|
JP7731359B2
(ja)
|
2020-08-28 |
2025-08-29 |
中外製薬株式会社 |
ヘテロ二量体Ｆｃポリペプチド
|
|
US20230338587A1
(en)
|
2020-08-31 |
2023-10-26 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
WO2022043557A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
|
CN116472060A
(zh)
|
2020-09-02 |
2023-07-21 |
健玛保 |
抗体疗法
|
|
MX2023002542A
(es)
|
2020-09-10 |
2023-03-15 |
Genmab As |
Anticuerpo biespecifico contra cumulo de difirenciacion 3 (cd3) y cumulo de difirenciacion 20 (cd20) en terapia combinada para el tratamiento del linfoma difuso de celulas b grandes.
|
|
BR112023004351A2
(pt)
|
2020-09-10 |
2023-04-04 |
Genmab As |
Método para tratar linfoma folicular em um sujeito humano
|
|
IL301100A
(en)
|
2020-09-10 |
2023-05-01 |
Genmab As |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
|
BR112023004216A2
(pt)
|
2020-09-10 |
2023-04-11 |
Genmab As |
Método para tratar linfoma folicular em um sujeito humano
|
|
JP2023541858A
(ja)
|
2020-09-10 |
2023-10-04 |
ジェンマブ エー／エス |
慢性リンパ球性白血病を治療するためのｃｄ３及びｃｄ２０に対する二重特異性抗体
|
|
BR112023004321A2
(pt)
|
2020-09-10 |
2023-04-04 |
Genmab As |
Método para tratar linfoma de célula b grande difusa em um sujeito humano
|
|
TW202227495A
(zh)
|
2020-09-11 |
2022-07-16 |
美商健生生物科技公司 |
用於調節β鏈介導之免疫的方法及組成物
|
|
WO2022056197A1
(en)
|
2020-09-11 |
2022-03-17 |
Janssen Biotech, Inc. |
Immune targeting molecules and uses thereof
|
|
IL301513A
(en)
|
2020-10-02 |
2023-05-01 |
Genmab As |
Antibodies capable of binding to ror2 and bispecific antibodies binding to ror2 and cd3
|
|
EP4225786A2
(en)
|
2020-10-07 |
2023-08-16 |
Amgen Inc. |
Rational selection of building blocks for the assembly of multispecific antibodies
|
|
KR20230086765A
(ko)
|
2020-10-13 |
2023-06-15 |
얀센 바이오테크 인코포레이티드 |
분화 클러스터 iv 및/또는 viii을 조절하기 위한 바이오-조작된 t 세포 매개 면역, 물질 및 기타 방법
|
|
JP2023547795A
(ja)
|
2020-10-15 |
2023-11-14 |
ユーシービー バイオファルマ エスアールエル |
Ｃｄ４５を多量体化する結合分子
|
|
TW202233672A
(zh)
|
2020-10-22 |
2022-09-01 |
美商健生生物科技公司 |
包括類δ配體３（ＤＬＬ３）抗原結合區之蛋白質及其用途
|
|
EP4237003A4
(en)
|
2020-10-28 |
2025-07-09 |
Janssen Biotech Inc |
COMPOSITIONS AND METHODS FOR MODULATING GAMMA DELTA CHAIN-MEDIATED IMMUNITY
|
|
MX2023005130A
(es)
|
2020-11-04 |
2023-05-25 |
Genentech Inc |
Dosis subcutanea de anticuerpos biespecificos anti-cd20/anti-cd3.
|
|
TWI874719B
(zh)
|
2020-11-04 |
2025-03-01 |
美商建南德克公司 |
用抗cd20/抗cd3雙特異性抗體進行治療之給藥
|
|
US20240002509A1
(en)
|
2020-11-06 |
2024-01-04 |
Novartis Ag |
ANTIBODY Fc VARIANTS
|
|
AU2021373366A1
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Cd19 binding molecules and uses thereof
|
|
KR20230104222A
(ko)
|
2020-11-06 |
2023-07-07 |
노파르티스 아게 |
B 세포 악성종양 치료를 위한 항-cd19 작용제 및 b 세포 표적화제 병용 요법
|
|
EP4244246A1
(en)
|
2020-11-10 |
2023-09-20 |
Amgen Inc. |
Novel linkers of multispecific antigen binding domains
|
|
CN116635062A
(zh)
|
2020-11-13 |
2023-08-22 |
诺华股份有限公司 |
使用表达嵌合抗原受体（car）的细胞的组合疗法
|
|
AU2021390501A1
(en)
|
2020-12-01 |
2023-06-29 |
Aptevo Research And Development Llc |
Heterodimeric psma and cd3-binding bispecific antibodies
|
|
WO2022122652A1
(en)
|
2020-12-07 |
2022-06-16 |
UCB Biopharma SRL |
Antibodies against interleukin-22
|
|
IL303424A
(en)
|
2020-12-07 |
2023-08-01 |
Genmab As |
Antibody and taxane combination therapy
|
|
AU2021395729A1
(en)
|
2020-12-07 |
2023-07-13 |
UCB Biopharma SRL |
Multi-specific antibodies and antibody combinations
|
|
JP2024504758A
(ja)
|
2021-01-28 |
2024-02-01 |
ヤンセン バイオテツク，インコーポレーテツド |
Ｐｓｍａ結合タンパク質及びその使用
|
|
US20240141060A1
(en)
|
2021-01-29 |
2024-05-02 |
Novartis Ag |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
|
IL305144A
(en)
|
2021-02-16 |
2023-10-01 |
Janssen Pharmaceutica Nv |
Trispecific antibodies targeting BCMA, GPRC5D and CD3
|
|
BR112023016360A2
(pt)
|
2021-02-16 |
2024-01-23 |
Janssen Biotech Inc |
Materiais e métodos para determinação aprimorada de ligante alvo
|
|
WO2022187539A1
(en)
|
2021-03-03 |
2022-09-09 |
Dragonfly Therapeutics, Inc. |
Methods of treating cancer using multi-specific binding proteins that bind nkg2d, cd16 and a tumor-associated antigen
|
|
WO2022187591A1
(en)
|
2021-03-05 |
2022-09-09 |
Go Therapeutics, Inc. |
Anti-glyco-cd44 antibodies and their uses
|
|
CA3212665A1
(en)
|
2021-03-09 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
|
US20220298248A1
(en)
|
2021-03-09 |
2022-09-22 |
Janssen Biotech, Inc. |
Treatment of Cancers Lacking EGFR- Activating Mutations
|
|
MX2023010512A
(es)
|
2021-03-09 |
2023-12-08 |
Genmab As |
Agentes de union multiespecificos contra cd40 y cd137 en terapia.
|
|
WO2022192586A1
(en)
|
2021-03-10 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
|
CA3210971A1
(en)
|
2021-03-12 |
2022-09-15 |
Bart-Jan DE KREUK |
Non-activating antibody variants
|
|
EP4314070A1
(en)
|
2021-03-24 |
2024-02-07 |
Janssen Biotech, Inc. |
Trispecific antibody targeting cd79b, cd20, and cd3
|
|
EP4314056A1
(en)
|
2021-03-24 |
2024-02-07 |
Janssen Biotech, Inc. |
Proteins comprising cd3 antigen binding domains and uses thereof
|
|
IL306103A
(en)
|
2021-03-24 |
2023-11-01 |
Janssen Biotech Inc |
The antibody targets CD22 and CD79B
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
US20240228659A1
(en)
|
2021-04-14 |
2024-07-11 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve nk cells cytotoxicity
|
|
WO2022221505A2
(en)
|
2021-04-14 |
2022-10-20 |
Aro Biotherapeutics Company |
Cd71 binding fibronectin type iii domains
|
|
IL307595A
(en)
|
2021-04-14 |
2023-12-01 |
Aro Biotherapeutics Company |
FN3 RNA-silencing region conjugates and their uses
|
|
US20240190993A1
(en)
|
2021-04-14 |
2024-06-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve the anti-tumoral activity of macrophages
|
|
TW202308689A
(zh)
*
|
2021-04-21 |
2023-03-01 |
美商健生生物科技公司 |
高濃度的雙特異性抗體調配物
|
|
WO2022233764A1
(en)
|
2021-05-03 |
2022-11-10 |
UCB Biopharma SRL |
Antibodies
|
|
IL308300A
(en)
|
2021-05-07 |
2024-01-01 |
Genmab As |
PHARMACEUTICAL COMPOSITIONS COMPRISING BISPECIFIC ANTIBODIES BINDING TO B7H4 and CD3
|
|
EP4337330A1
(en)
|
2021-05-14 |
2024-03-20 |
Genentech, Inc. |
Methods for treatment of cd20-positive proliferative disorder with mosunetuzumab and polatuzumab vedotin
|
|
TW202309094A
(zh)
|
2021-05-18 |
2023-03-01 |
美商健生生物科技公司 |
用於識別癌症患者以進行組合治療之方法
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
US12258411B2
(en)
|
2021-06-04 |
2025-03-25 |
Amgen Inc. |
Anti-CCR8 antibodies and uses thereof
|
|
IL309349A
(en)
|
2021-06-14 |
2024-02-01 |
argenx BV |
Antibodies against interleukin 9 and methods of using them
|
|
IL309319A
(en)
|
2021-06-21 |
2024-02-01 |
Genmab As |
Combined dosage regimen CD137 and PD-L1 binding agents
|
|
JP7477127B2
(ja)
|
2021-06-25 |
2024-05-01 |
中外製薬株式会社 |
抗ｃｔｌａ－４抗体の使用
|
|
CR20240026A
(es)
|
2021-06-25 |
2024-03-14 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-ctla-4
|
|
EP4367138A1
(en)
|
2021-07-09 |
2024-05-15 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-il12/il23 antibody compositions
|
|
KR20240032991A
(ko)
|
2021-07-09 |
2024-03-12 |
얀센 바이오테크 인코포레이티드 |
항-tnf 항체 조성물의 생성을 위한 제조 방법
|
|
EP4367136A1
(en)
|
2021-07-09 |
2024-05-15 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
|
US20240327544A1
(en)
|
2021-07-13 |
2024-10-03 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
|
US20250101126A1
(en)
|
2021-08-05 |
2025-03-27 |
Go Therapeutics, Inc. |
Anti-glyco-muc4 antibodies and their uses
|
|
GB202111905D0
(en)
|
2021-08-19 |
2021-10-06 |
UCB Biopharma SRL |
Antibodies
|
|
WO2023034571A1
(en)
|
2021-09-03 |
2023-03-09 |
Go Therapeutics, Inc. |
Anti-glyco-lamp1 antibodies and their uses
|
|
AU2022339667A1
(en)
|
2021-09-03 |
2024-04-11 |
Go Therapeutics, Inc. |
Anti-glyco-cmet antibodies and their uses
|
|
TW202328192A
(zh)
|
2021-09-06 |
2023-07-16 |
荷蘭商珍美寶公司 |
能結合ｃｄ２７之抗體、彼之變異體及彼等之用途
|
|
AU2022344595A1
(en)
|
2021-09-13 |
2024-05-02 |
Janssen Biotech, Inc |
CD33 X Vδ2 MULTISPECIFIC ANTIBODIES FOR THE TREATMENT OF CANCER
|
|
WO2023044483A2
(en)
|
2021-09-20 |
2023-03-23 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
WO2023046322A1
(en)
|
2021-09-24 |
2023-03-30 |
Janssen Pharmaceutica Nv |
Proteins comprising cd20 binding domains, and uses thereof
|
|
WO2023053282A1
(ja)
|
2021-09-29 |
2023-04-06 |
中外製薬株式会社 |
がんの治療に用いるための細胞傷害誘導治療剤
|
|
AU2022361184A1
(en)
|
2021-10-08 |
2024-05-09 |
Chugai Seiyaku Kabushiki Kaisha |
Method for preparing prefilled syringe formulation
|
|
WO2023057571A1
(en)
|
2021-10-08 |
2023-04-13 |
Genmab A/S |
Antibodies binding to cd30 and cd3
|
|
GB202115122D0
(en)
|
2021-10-21 |
2021-12-08 |
Dualyx Nv |
Binding molecules targeting IL-2 receptor
|
|
IL312464A
(en)
|
2021-11-01 |
2024-06-01 |
Janssen Biotech Inc |
Compositions and methods for the modulation of beta chain-mediated immunity
|
|
IL312503A
(en)
|
2021-11-03 |
2024-07-01 |
Janssen Biotech Inc |
Methods of treating cancers and enhancing efficacy of bcmaxcd3 bispecific antibodies
|
|
WO2023092004A1
(en)
|
2021-11-17 |
2023-05-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
US20230183360A1
(en)
|
2021-12-09 |
2023-06-15 |
Janssen Biotech, Inc. |
Use of Amivantamab to Treat Colorectal Cancer
|
|
EP4469163A1
(en)
|
2022-01-24 |
2024-12-04 |
Novimmune S.A. |
Composition and methods for the selective activation of cytokine signaling pathways
|
|
EP4469082A1
(en)
|
2022-01-28 |
2024-12-04 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
|
US20230303693A1
(en)
|
2022-01-28 |
2023-09-28 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
|
US20230383010A1
(en)
|
2022-02-07 |
2023-11-30 |
Visterra, Inc. |
Anti-idiotype antibody molecules and uses thereof
|
|
TW202342057A
(zh)
|
2022-02-07 |
2023-11-01 |
美商健生生物科技公司 |
用於減少用ｅｇｆｒ／ｍｅｔ雙特異性抗體治療之患者的輸注相關反應之方法
|
|
JP2025508066A
(ja)
|
2022-03-07 |
2025-03-21 |
ノビミューン エスアー |
目的としたｔ細胞活性化のためのｃｄ２８二重特異性抗体
|
|
IL315065A
(en)
|
2022-03-14 |
2024-10-01 |
LamKap Bio gamma AG |
GPC3XCD28 and GPC3XCD3 bispecific antibodies and their combination for targeted killing of GPC3-positive malignant cells
|
|
WO2023174521A1
(en)
|
2022-03-15 |
2023-09-21 |
Genmab A/S |
Binding agents binding to epcam and cd137
|
|
JP2025513714A
(ja)
|
2022-03-22 |
2025-04-30 |
モルフォシス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
Ｃｄ３に特異的な脱免疫抗体
|
|
CA3245704A1
(en)
|
2022-03-29 |
2023-10-05 |
Ngm Biopharmaceuticals, Inc. |
ILT3 AND CD3 LINKING AGENTS AND THEIR METHODS OF USE
|
|
WO2023198839A2
(en)
|
2022-04-13 |
2023-10-19 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20
|
|
PE20251172A1
(es)
|
2022-04-26 |
2025-04-23 |
Novartis Ag |
Anticuerpos multiespecificos que se dirigen a il-13 e il-18
|
|
WO2023218046A1
(en)
|
2022-05-12 |
2023-11-16 |
Genmab A/S |
Binding agents capable of binding to cd27 in combination therapy
|
|
IL316632A
(en)
|
2022-05-12 |
2024-12-01 |
Genmab As |
Binding agents capable of binding to CD27 in combination therapy
|
|
US20250295809A1
(en)
|
2022-05-13 |
2025-09-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
|
MA71324A
(fr)
|
2022-06-30 |
2025-04-30 |
Janssen Biotech, Inc. |
Utilisation d'un anticorps anti-egfr/anti-met pour traiter le cancer gastrique ou oesophagien
|
|
TW202435912A
(zh)
|
2022-08-03 |
2024-09-16 |
美商航海家醫療公司 |
用於穿過血腦屏障之組合物及方法
|
|
JP2025531832A
(ja)
|
2022-09-08 |
2025-09-25 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
ＬＴＢＰ２（潜在的形質転換増殖因子β結合タンパク質２）に対する特異性を有する抗体及びその使用
|
|
JP2025535203A
(ja)
|
2022-09-15 |
2025-10-23 |
ボイジャー セラピューティクス インコーポレイテッド |
タウ結合化合物
|
|
WO2024079074A1
(en)
|
2022-10-10 |
2024-04-18 |
Universite D'aix Marseille |
ANTI-sCD146 ANTIBODIES AND USES THEREOF
|
|
WO2024084052A1
(en)
|
2022-10-21 |
2024-04-25 |
Novimmune Sa |
Pd-l1xcd28 bispecific antibodies for immune checkpoint-dependent t cell activation
|
|
WO2024089551A1
(en)
|
2022-10-25 |
2024-05-02 |
Janssen Biotech, Inc. |
Msln and cd3 binding agents and methods of use thereof
|
|
TW202432177A
(zh)
|
2022-10-31 |
2024-08-16 |
丹麥商珍美寶股份有限公司 |
Ｃｄ３８抗體及其用途
|
|
KR20250097946A
(ko)
|
2022-11-02 |
2025-06-30 |
얀센 바이오테크 인코포레이티드 |
암을 치료하는 방법
|
|
EP4612179A1
(en)
|
2022-11-02 |
2025-09-10 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20 for treating richter's syndrome
|
|
CN120456922A
(zh)
|
2022-11-25 |
2025-08-08 |
国立大学法人大阪大学 |
针对血液癌的抗体
|
|
CN120265651A
(zh)
|
2022-11-25 |
2025-07-04 |
中外制药株式会社 |
用于生产蛋白质的方法
|
|
WO2024115725A1
(en)
|
2022-12-01 |
2024-06-06 |
BioNTech SE |
Multispecific antibody against cd40 and cd137 in combination therapy with anti-pd1 ab and chemotherapy
|
|
WO2024144396A1
(en)
|
2022-12-27 |
2024-07-04 |
Merus N.V. |
Method for generating bispecific proteins
|
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
|
AU2024217296A1
(en)
|
2023-02-09 |
2025-09-25 |
Janssen Biotech, Inc. |
Anti-v beta 17/anti-cd123 bispecific antibodies
|
|
AU2024236678A1
(en)
|
2023-03-13 |
2025-10-30 |
Janssen Biotech, Inc. |
Combination therapies with bi-specific anti-egfr/c-met antibodies and anti-pd-1 antibodies
|
|
WO2024194685A2
(en)
|
2023-03-17 |
2024-09-26 |
Oxitope Pharma B.V. |
Anti-phosphocholine antibodies and methods of use thereof
|
|
AU2024240129A1
(en)
|
2023-03-17 |
2025-10-09 |
Oxitope Pharma B.V. |
Anti-phosphocholine antibodies and methods of use thereof
|
|
WO2024208898A1
(en)
|
2023-04-05 |
2024-10-10 |
Genmab A/S |
Pharmaceutical compositions comprising antibodies binding to cd30 and cd3
|
|
TW202504915A
(zh)
|
2023-04-13 |
2025-02-01 |
丹麥商珍美寶股份有限公司 |
以抗ｃｄ３及ｃｄ２０之雙特異性抗體治療淋巴瘤之方法
|
|
AU2024271605A1
(en)
|
2023-05-12 |
2025-11-13 |
BioNTech SE |
Antibodies capable of binding to ox40, variants thereof and uses thereof
|
|
CA3228195A1
(en)
|
2023-05-23 |
2025-06-30 |
Janssen Biotech, Inc. |
Methods for treatment of non-small cell lung cancer (nsclc)
|
|
WO2025007037A1
(en)
|
2023-06-28 |
2025-01-02 |
Dragonfly Therapeutics, Inc. |
Variant il-2 proteins
|
|
JP2025530208A
(ja)
|
2023-06-30 |
2025-09-11 |
ジェンマブ エー／エス |
線維芽細胞活性化タンパク質アルファおよびデスレセプター４に結合する抗体
|
|
US12319747B2
(en)
|
2023-07-03 |
2025-06-03 |
Medicovestor, Inc. |
Methods of using anti-SP17 immunotherapeutics
|
|
GB2632290A
(en)
*
|
2023-07-31 |
2025-02-05 |
Thermo Fisher Scient Bremen Gmbh |
A method, device and computer software for preparing a liquid protein sample for proteome analysis
|
|
WO2025027529A1
(en)
|
2023-07-31 |
2025-02-06 |
Advesya |
Anti-il-1rap antibody drug conjugates and methods of use thereof
|
|
US20250136688A1
(en)
|
2023-08-07 |
2025-05-01 |
Janssen Biotech, Inc. |
Stabilized cd3 antigen binding agents and methods of use thereof
|
|
US20250163182A1
(en)
|
2023-08-07 |
2025-05-22 |
Janssen Biotech, Inc. |
Enpp3 and cd3 binding agents and methods of use thereof
|
|
WO2025034715A1
(en)
|
2023-08-07 |
2025-02-13 |
Janssen Biotech, Inc. |
Gucy2c antibodies and uses thereof
|
|
WO2025038600A1
(en)
|
2023-08-14 |
2025-02-20 |
Amgen Inc. |
Methods for reducing yellow color
|
|
WO2025042709A1
(en)
|
2023-08-22 |
2025-02-27 |
Eli Lilly And Company |
AMYLOID PRECURSOR PROTEIN (APP) RNAi AGENTS
|
|
WO2025052273A1
(en)
|
2023-09-05 |
2025-03-13 |
Janssen Biotech, Inc. |
Methods of treating non-small cell lung cancer
|
|
WO2025051895A1
(en)
|
2023-09-06 |
2025-03-13 |
Novimmune Sa |
Combination therapy with a cea x cd28 bispecific antibody and blocking anti-pd-1 antibodies for enhanced in vivo anti-tumor activity
|
|
WO2025054500A2
(en)
|
2023-09-08 |
2025-03-13 |
Mlab Biosciences, Inc. |
Bifunctional proteins and uses thereof
|
|
WO2025056180A1
(en)
|
2023-09-15 |
2025-03-20 |
BioNTech SE |
Methods of treatment using agents binding to epcam and cd137 in combination with pd-1 axis binding antagonists
|
|
WO2025079020A1
(en)
|
2023-10-12 |
2025-04-17 |
Janssen Biotech, Inc. |
First line treatment in egfr exon 20 insertion-mutated advanced non-small cell lung cancer
|
|
WO2025085352A1
(en)
|
2023-10-18 |
2025-04-24 |
Eli Lilly And Company |
Transferrin receptor binding proteins and uses thereof
|
|
US12364777B2
(en)
|
2023-10-20 |
2025-07-22 |
Medicovestor, Inc. |
Homodimeric antibodies for use in treating cancers and methods of use
|
|
WO2025114541A1
(en)
|
2023-11-30 |
2025-06-05 |
Genmab A/S |
Antibodies capable of binding to ox40 in combination therapy
|
|
WO2025122634A1
(en)
|
2023-12-05 |
2025-06-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
|
WO2025120015A1
(en)
|
2023-12-06 |
2025-06-12 |
Institut National de la Santé et de la Recherche Médicale |
Cd5 targeting antibodies with depleting and t or b-cell activation effects
|
|
TW202535947A
(zh)
|
2023-12-08 |
2025-09-16 |
美商健生生物科技公司 |
ＣＤ３３抗體、ＣＤ３３／Ｖδ２多特異性抗體及其用途
|
|
WO2025126102A1
(en)
|
2023-12-12 |
2025-06-19 |
Janssen Biotech, Inc. |
Enpp3 × cd3 bispecific antibodies and use thereof
|
|
TW202530255A
(zh)
|
2023-12-15 |
2025-08-01 |
法商亞維西亞有限公司 |
抗ｉｌ－１ｒａｐ結合結構域及其抗體－藥物偶聯物
|
|
WO2025133707A1
(en)
|
2023-12-19 |
2025-06-26 |
Vectory Therapeutics B.V. |
Anti-tdp-43 antibodies and uses thereof
|
|
WO2025137454A1
(en)
|
2023-12-21 |
2025-06-26 |
Amgen Inc. |
Stabilizing homodimer mutations for two cell heterodimer production
|
|
US12121587B1
(en)
|
2023-12-26 |
2024-10-22 |
Medicovestor, Inc. |
Dimeric antibodies
|
|
US12116410B1
(en)
|
2023-12-26 |
2024-10-15 |
Medicovestor, Inc. |
Methods of manufacturing dimeric antibodies
|
|
WO2025147334A1
(en)
*
|
2024-01-05 |
2025-07-10 |
Bright Biologics Llc |
ANTI-c-MET/HER2 ANTIBODIES AND USES THEREOF
|
|
WO2025153988A1
(en)
|
2024-01-16 |
2025-07-24 |
Janssen Biotech, Inc. |
Use of amivantamab to treat colorectal cancer
|
|
WO2025158277A1
(en)
|
2024-01-22 |
2025-07-31 |
Janssen Biotech, Inc. |
Use of amivantamab to treat head and neck cancer
|
|
US12258396B1
(en)
|
2024-02-02 |
2025-03-25 |
Medicovestor, Inc. |
Methods of using immunotherapeutics that bind folate receptor alpha
|
|
US12240900B1
(en)
|
2024-02-02 |
2025-03-04 |
Medicovestor, Inc. |
Nucleic acids, vectors, and cells that encode antibodies and other proteins that bind folate receptor alpha
|
|
WO2025166107A1
(en)
|
2024-02-02 |
2025-08-07 |
Eli Lilly And Company |
Cns tagrted sarm1 rnai agents
|
|
US12378314B1
(en)
|
2024-02-02 |
2025-08-05 |
Medicovestor, Inc. |
Proteins that bind folate receptor alpha including fully-human antibodies
|
|
WO2025166111A1
(en)
|
2024-02-02 |
2025-08-07 |
Eli Lilly And Company |
Conjugates comprising transferrin receptor binding protein
|
|
WO2025191459A1
(en)
|
2024-03-11 |
2025-09-18 |
Janssen Biotech, Inc. |
Use of bispecific anti-egfr/c-met antibodies to treat solid tumors
|
|
WO2025221728A2
(en)
|
2024-04-15 |
2025-10-23 |
Janssen Biotech, Inc. |
Ltbr binding molecules and uses thereof
|
|
WO2025224297A1
(en)
|
2024-04-26 |
2025-10-30 |
Institut National de la Santé et de la Recherche Médicale |
Antibodies having specificity to tgfbi and uses thereof
|
|
WO2025231372A2
(en)
|
2024-05-03 |
2025-11-06 |
Janssen Biotech, Inc. |
Methods for treating multiple myeloma with car-t cells and bispecific antibodies
|
|
WO2025231408A2
(en)
|
2024-05-03 |
2025-11-06 |
Janssen Biotech, Inc. |
Methods for treating multiple myeloma with car-t cells and bispecific antibodies
|
|
WO2025233825A1
(en)
|
2024-05-06 |
2025-11-13 |
Janssen Pharmaceutica Nv |
Enrichment of cells expressing a bird linker
|
|
WO2025238133A1
(en)
|
2024-05-17 |
2025-11-20 |
UCB Biopharma SRL |
Multispecific antibody with binding specificity for il-11 and il-17
|
|
WO2025238135A2
(en)
|
2024-05-17 |
2025-11-20 |
UCB Biopharma SRL |
Antibody with binding specificity for il-11
|
|
WO2025242732A1
(en)
|
2024-05-21 |
2025-11-27 |
Institut National de la Santé et de la Recherche Médicale |
Pan antibodies against sars-cov-2 spike protein and uses thereof for therapeutical purposes
|
|
WO2025243243A1
(en)
|
2024-05-24 |
2025-11-27 |
Janssen Biotech, Inc. |
Bispecific antibody targeting emr2 (cd312) and the t-cell receptor trbv19
|
|
WO2025250605A1
(en)
|
2024-05-31 |
2025-12-04 |
Eli Lilly And Company |
Acvr2a and acvr2b rna interference agents
|
|
CN120441709B
(zh)
*
|
2025-07-02 |
2025-09-16 |
中国药科大学 |
一种靶向cd47和her2的双特异性抗体及其制备方法、应用
|