EP3623473A1
(en)
|
2005-03-31 |
2020-03-18 |
Chugai Seiyaku Kabushiki Kaisha |
Process for production of polypeptide by regulation of assembly
|
US9670269B2
(en)
|
2006-03-31 |
2017-06-06 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of modifying antibodies for purification of bispecific antibodies
|
JP5624276B2
(en)
|
2006-03-31 |
2014-11-12 |
中外製薬株式会社 |
Methods for controlling blood kinetics of antibodies
|
ES2667863T3
(en)
|
2007-03-29 |
2018-05-14 |
Genmab A/S |
Bispecific antibodies and their production methods
|
CA2688275A1
(en)
*
|
2007-05-31 |
2008-12-04 |
Genmab A/S |
Stable igg4 antibodies
|
ES2566957T3
(en)
|
2007-09-26 |
2016-04-18 |
Chugai Seiyaku Kabushiki Kaisha |
Constant region of modified antibody
|
EP3689912A1
(en)
|
2007-09-26 |
2020-08-05 |
Chugai Seiyaku Kabushiki Kaisha |
Method of modifying isoelectric point of antibody via amino acid substitution in cdr
|
DK2235064T3
(en)
*
|
2008-01-07 |
2016-01-11 |
Amgen Inc |
A process for the preparation of heterodimeric Fc molecules using electrostatic control effects
|
TWI682995B
(en)
|
2009-03-19 |
2020-01-21 |
日商中外製藥股份有限公司 |
Antibody constant region alteration
|
JP5717624B2
(en)
|
2009-03-19 |
2015-05-13 |
中外製薬株式会社 |
Antibody constant region variants
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
JP5837821B2
(en)
|
2009-09-24 |
2015-12-24 |
中外製薬株式会社 |
Antibody constant region variants
|
JP5889181B2
(en)
|
2010-03-04 |
2016-03-22 |
中外製薬株式会社 |
Antibody constant region variants
|
US9150663B2
(en)
|
2010-04-20 |
2015-10-06 |
Genmab A/S |
Heterodimeric antibody Fc-containing proteins and methods for production thereof
|
EP2569337A1
(en)
|
2010-05-14 |
2013-03-20 |
Rinat Neuroscience Corp. |
Heterodimeric proteins and methods for producing and purifying them
|
AU2016201799B2
(en)
*
|
2010-05-27 |
2017-09-07 |
Genmab A/S |
Monoclonal antibodies aganst HER2 epitope
|
EP2575880B1
(en)
|
2010-05-27 |
2019-01-16 |
Genmab A/S |
Monoclonal antibodies against her2 epitope
|
EP3539988A3
(en)
|
2010-05-27 |
2019-12-04 |
Genmab A/S |
Monoclonal antibodies against her2
|
CN103052649B
(en)
|
2010-07-29 |
2015-12-16 |
Xencor公司 |
There is the antibody of the iso-electric point of amendment
|
MX355060B
(en)
|
2010-11-17 |
2018-04-03 |
Chugai Pharmaceutical Co Ltd |
Multi-specific antigen-binding molecule having alternative function to function of blood coagulation factor viii.
|
AU2012245116A1
(en)
*
|
2011-04-20 |
2013-11-07 |
Genmab A/S |
Bispecific antibodies against HER2 and CD3
|
US20140170148A1
(en)
*
|
2011-04-20 |
2014-06-19 |
Genmab A/S |
Bispecific antibodies against her2
|
EP2699260A1
(en)
*
|
2011-04-20 |
2014-02-26 |
Genmab A/S |
Bispecifc antibodies against her2
|
WO2012143523A1
(en)
|
2011-04-20 |
2012-10-26 |
Genmab A/S |
Bispecifc antibodies against her2
|
KR20200120743A
(en)
*
|
2011-07-06 |
2020-10-21 |
젠맵 비. 브이 |
Antibody variants and uses thereof
|
UA117901C2
(en)
|
2011-07-06 |
2018-10-25 |
Ґенмаб Б.В. |
Antibody variants and uses thereof
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
KR102106002B1
(en)
*
|
2011-10-11 |
2020-05-07 |
제넨테크, 인크. |
Improved assembly of bispecific antibodies
|
EP2771364B1
(en)
*
|
2011-10-27 |
2019-05-22 |
Genmab A/S |
Production of heterodimeric proteins
|
US11851476B2
(en)
|
2011-10-31 |
2023-12-26 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule having regulated conjugation between heavy-chain and light-chain
|
RS61161B1
(en)
|
2011-12-13 |
2021-01-29 |
Engeneic Molecular Delivery Pty Ltd |
Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors
|
LT2802607T
(en)
*
|
2012-01-13 |
2018-02-12 |
Julius-Maximilians-Universität Würzburg |
Dual antigen-induced bipartite functional complementation
|
US9212227B2
(en)
|
2012-04-30 |
2015-12-15 |
Janssen Biotech, Inc. |
ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions
|
CA2873720A1
(en)
*
|
2012-05-10 |
2013-11-14 |
Zymeworks Inc. |
Single-arm monovalent antibody constructs and uses thereof
|
CA2872540A1
(en)
*
|
2012-05-10 |
2013-11-14 |
Zymeworks Inc. |
Heteromultimer constructs of immunoglobulin heavy chains with mutations in the fc domain
|
CN104736174B
(en)
|
2012-07-06 |
2019-06-14 |
根马布私人有限公司 |
Protein dimer with triple mutant
|
EP3632462A1
(en)
|
2012-07-06 |
2020-04-08 |
Genmab B.V. |
Dimeric protein with triple mutations
|
MX371442B
(en)
|
2012-08-24 |
2020-01-30 |
Chugai Pharmaceutical Co Ltd |
Fcyriib-specific fc region variant.
|
IN2015MN00139A
(en)
*
|
2012-09-25 |
2015-10-16 |
Glenmark Pharmaceuticals Sa |
|
US9695228B2
(en)
|
2012-11-21 |
2017-07-04 |
Janssen Biotech, Inc. |
EGFR and c-Met fibronectin type III domain binding molecules
|
HUE041499T2
(en)
*
|
2012-11-21 |
2019-05-28 |
Janssen Biotech Inc |
Bispecific egfr/c-met antibodies
|
EP2927321B1
(en)
|
2012-11-27 |
2021-02-17 |
Ajou University Industry-Academic Cooperation Foundation |
Ch3 domain variant pair inducing formation of heterodimer of heavy chain constant region of antibody at high efficiency, method for preparing same, and use thereof
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
CA2893562C
(en)
|
2012-11-28 |
2023-09-12 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
KR20160007478A
(en)
*
|
2013-01-10 |
2016-01-20 |
젠맵 비. 브이 |
Human igg1 fc region variants and uses thereof
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
WO2014110601A1
(en)
|
2013-01-14 |
2014-07-17 |
Xencor, Inc. |
Novel heterodimeric proteins
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
WO2014113510A1
(en)
|
2013-01-15 |
2014-07-24 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
WO2014122144A1
(en)
|
2013-02-05 |
2014-08-14 |
Engmab Ag |
BISPECIFIC ANTIBODIES AGAINST CD3ε AND BCMA
|
DK2970486T3
(en)
|
2013-03-15 |
2018-08-06 |
Xencor Inc |
MODULATION OF T-CELLS WITH BISPECIFIC ANTIBODIES AND FC-FUSIONS
|
EP2968440B1
(en)
|
2013-03-15 |
2019-06-05 |
Zymeworks Inc. |
Cytotoxic and anti-mitotic compounds, and methods of using the same
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
EP2970461A4
(en)
|
2013-03-15 |
2016-11-23 |
Janssen Biotech Inc |
Interferon alpha and omega antibody antagonists
|
PT2976361T
(en)
|
2013-03-18 |
2018-10-19 |
Janssen Pharmaceuticals Inc |
Humanized anti-cd134 (ox40) antibodies and uses thereof
|
EP3783017A1
(en)
|
2013-04-02 |
2021-02-24 |
Chugai Seiyaku Kabushiki Kaisha |
Fc region variant
|
CA2904805A1
(en)
|
2013-04-29 |
2014-11-06 |
F. Hoffmann-La Roche Ag |
Fc-receptor binding modified asymmetric antibodies and methods of use
|
KR20210094669A
(en)
*
|
2013-04-29 |
2021-07-29 |
에프. 호프만-라 로슈 아게 |
Human fcrn-binding modified antibodies and methods of use
|
EP3327034A1
(en)
*
|
2013-04-29 |
2018-05-30 |
F. Hoffmann-La Roche AG |
Fcrn-binding abolished anti-igf-1r antibodies and their use in the treatment of vascular eye diseases
|
RU2655439C2
(en)
*
|
2013-05-31 |
2018-05-28 |
Займворкс Инк. |
Heteromultimers with reduced or silenced effector function
|
EP3693385A1
(en)
|
2013-07-05 |
2020-08-12 |
Genmab A/S |
Humanized or chimeric cd3 antibodies
|
DK3050896T3
(en)
|
2013-09-27 |
2021-07-19 |
Chugai Pharmaceutical Co Ltd |
Process for the preparation of a polypeptide heteromultimer
|
AU2014334627B2
(en)
|
2013-10-14 |
2019-07-25 |
Janssen Biotech, Inc. |
Cysteine engineered fibronectin type III domain binding molecules
|
SG11201603244VA
(en)
|
2013-11-04 |
2016-05-30 |
Glenmark Pharmaceuticals Sa |
Production of t cell retargeting hetero-dimeric immunoglobulins
|
UA119973C2
(en)
|
2013-11-06 |
2019-09-10 |
Янссен Байотек, Інк. |
Anti-ccl17 antibodies
|
CN113278076A
(en)
|
2013-11-11 |
2021-08-20 |
中外制药株式会社 |
Antigen binding molecules comprising altered antibody variable regions
|
ES2811923T3
(en)
|
2013-12-17 |
2021-03-15 |
Genentech Inc |
Anti-CD3 antibodies and methods of use
|
EP3086815B1
(en)
|
2013-12-27 |
2022-02-09 |
Zymeworks Inc. |
Sulfonamide-containing linkage systems for drug conjugates
|
KR20160104636A
(en)
|
2014-01-15 |
2016-09-05 |
에프. 호프만-라 로슈 아게 |
Fc-region variants with improved protein a-binding
|
JOP20200094A1
(en)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
Antibody molecules to pd-1 and uses thereof
|
JOP20200096A1
(en)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
Antibody molecules to tim-3 and uses thereof
|
DK3105252T3
(en)
|
2014-02-12 |
2019-10-14 |
Michael Uhlin |
BISPECIFIC ANTIBODIES FOR USE IN STEM CELL TRANSPLANTATION
|
US9732154B2
(en)
|
2014-02-28 |
2017-08-15 |
Janssen Biotech, Inc. |
Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
|
US20150259420A1
(en)
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
JP2017513818A
(en)
|
2014-03-15 |
2017-06-01 |
ノバルティス アーゲー |
Treatment of cancer using chimeric antigen receptors
|
WO2015143271A1
(en)
*
|
2014-03-21 |
2015-09-24 |
X-Body, Inc. |
Bi-specific antigen-binding polypeptides
|
ME03666B
(en)
|
2014-03-28 |
2020-10-20 |
Xencor Inc |
Bispecific antibodies that bind to cd38 and cd3
|
EP4050026A1
(en)
|
2014-04-01 |
2022-08-31 |
Adimab, LLC |
Method of obtaining or identifying one or more common light chains for use in preparing a multispecific antibody
|
IL247715B
(en)
|
2014-04-07 |
2022-07-01 |
Chugai Pharmaceutical Co Ltd |
Immunoactivating antigen-binding molecule
|
ES2955736T3
(en)
*
|
2014-05-06 |
2023-12-05 |
Hoffmann La Roche |
Production of heteromultimeric proteins using mammalian cells
|
EP3144388B1
(en)
|
2014-05-13 |
2020-07-01 |
Chugai Seiyaku Kabushiki Kaisha |
T cell-redirecting antigen-binding molecule for cells having immunosuppression function
|
EP3107938B1
(en)
|
2014-05-28 |
2022-05-04 |
Zymeworks Inc. |
Modified antigen binding polypeptide constructs and uses thereof
|
US10647777B2
(en)
*
|
2014-05-28 |
2020-05-12 |
Genzyme Corporation |
Methods of controlling the formation of disulfide bonds in protein solutions
|
GB201409558D0
(en)
|
2014-05-29 |
2014-07-16 |
Ucb Biopharma Sprl |
Method
|
TWI713453B
(en)
|
2014-06-23 |
2020-12-21 |
美商健生生物科技公司 |
Interferon alpha and omega antibody antagonists
|
EP3161002A1
(en)
|
2014-06-27 |
2017-05-03 |
Innate Pharma |
MULTISPECIFIC NKp46 BINDING PROTEINS
|
WO2015197598A2
(en)
|
2014-06-27 |
2015-12-30 |
Innate Pharma |
Multispecific antigen binding proteins
|
EA201790173A1
(en)
|
2014-07-11 |
2017-06-30 |
Генмаб А/С |
ANTIBODIES CONNECTING AXL
|
GB201412659D0
(en)
|
2014-07-16 |
2014-08-27 |
Ucb Biopharma Sprl |
Molecules
|
GB201412658D0
(en)
|
2014-07-16 |
2014-08-27 |
Ucb Biopharma Sprl |
Molecules
|
CA2955154C
(en)
|
2014-07-21 |
2023-10-31 |
Novartis Ag |
Treatment of cancer using a cd33 chimeric antigen receptor
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
MY181834A
(en)
|
2014-07-21 |
2021-01-08 |
Novartis Ag |
Treatment of cancer using humanized anti-bcma chimeric antigen receptor
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
EP4205749A1
(en)
|
2014-07-31 |
2023-07-05 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing cells
|
CA2958200A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using a gfr alpha-4 chimeric antigen receptor
|
PL3183268T3
(en)
|
2014-08-19 |
2020-09-07 |
Novartis Ag |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
MA42561A
(en)
|
2014-09-02 |
2018-04-25 |
Immunogen Inc |
METHODS FOR FORMULATING ANTIBODY-DRUG CONJUGATE COMPOSITIONS
|
WO2016036916A1
(en)
*
|
2014-09-03 |
2016-03-10 |
Bioatla, Llc |
Discovering and producing conditionally active biologic proteins in the same eukaryotic cell production hosts
|
EA037647B1
(en)
|
2014-09-05 |
2021-04-27 |
Янссен Фармацевтика Нв |
Cd123 binding agents and uses thereof
|
MA40608A
(en)
|
2014-09-09 |
2016-03-17 |
Janssen Biotech Inc |
Combination therapies with anti-cd38 antibodies
|
CA2958479A1
(en)
|
2014-09-12 |
2016-03-17 |
Genentech, Inc. |
Anti-cll-1 antibodies and immunoconjugates
|
WO2016044605A1
(en)
|
2014-09-17 |
2016-03-24 |
Beatty, Gregory |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
EP4029873A1
(en)
|
2014-09-17 |
2022-07-20 |
Zymeworks Inc. |
Cytotoxic and anti-mitotic compounds, and methods of using the same
|
MA40764A
(en)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
THERAPEUTIC AGENT INDUCING CYTOTOXICITY
|
BR112017007379A2
(en)
|
2014-10-14 |
2017-12-19 |
Dana Farber Cancer Inst Inc |
antibody molecules to pd-l1 and uses thereof
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
KR102614189B1
(en)
*
|
2014-11-17 |
2023-12-18 |
리제너론 파아마슈티컬스, 인크. |
Methods for tumor treatment using cd3xcd20 bispecific antibody
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
EP3223907A2
(en)
|
2014-11-26 |
2017-10-04 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cd38
|
KR20170084326A
(en)
|
2014-11-26 |
2017-07-19 |
젠코어 인코포레이티드 |
Heterodimeric antibodies that bind cd3 and tumor antigens
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
US10398774B2
(en)
|
2014-12-09 |
2019-09-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Human monoclonal antibodies against AXL
|
WO2016097300A1
(en)
|
2014-12-19 |
2016-06-23 |
Genmab A/S |
Rodent bispecific heterodimeric proteins
|
US10428155B2
(en)
|
2014-12-22 |
2019-10-01 |
Xencor, Inc. |
Trispecific antibodies
|
CA2973159A1
(en)
*
|
2015-01-08 |
2016-07-14 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20
|
EP3056512A1
(en)
|
2015-02-10 |
2016-08-17 |
Medizinische Universität Wien |
Antibody construct
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
WO2016159213A1
(en)
*
|
2015-04-01 |
2016-10-06 |
中外製薬株式会社 |
Method for producing polypeptide hetero-oligomer
|
EP4056588A1
(en)
|
2015-04-08 |
2022-09-14 |
Novartis AG |
Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car)- expressing cell
|
GB201506869D0
(en)
|
2015-04-22 |
2015-06-03 |
Ucb Biopharma Sprl |
Method
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
EP3291836A4
(en)
|
2015-05-06 |
2018-11-14 |
Janssen Biotech, Inc. |
Prostate specific membrane antigen (psma) bispecific binding agents and uses thereof
|
CN108136218B
(en)
|
2015-05-20 |
2022-12-13 |
詹森生物科技公司 |
anti-CD 38 antibodies for the treatment of light chain amyloidosis and other CD 38-positive hematologic malignancies
|
MX2017014699A
(en)
|
2015-05-21 |
2018-04-11 |
Alligator Bioscience Ab |
Novel polypeptides.
|
TW201718647A
(en)
|
2015-06-16 |
2017-06-01 |
建南德克公司 |
Anti-CLL-1 antibodies and methods of use
|
RU2748943C2
(en)
|
2015-06-16 |
2021-06-02 |
Дженентек, Инк. |
HUMANIZED ANTIBODIES AND ANTIBODIES WITH MATURE AFFINITY AGAINST FcRH5 AND METHODS FOR THEIR APPLICATION
|
AU2016282674B2
(en)
|
2015-06-22 |
2022-01-13 |
Janssen Biotech, Inc. |
Combination therapies for heme malignancies with anti-CD38 antibodies and survivin inhibitors
|
EP3313881A1
(en)
|
2015-06-23 |
2018-05-02 |
Innate Pharma |
Multispecific nk engager proteins
|
SI3313441T1
(en)
|
2015-06-24 |
2024-05-31 |
Janssen Biotech, Inc., |
Immune modulation and treatment of solid tumors with antibodies that specifically bind cd38
|
SI3313845T1
(en)
|
2015-06-29 |
2021-01-29 |
Immunogen, Inc. |
Conjugates of cysteine engineered antibodies
|
ES2973885T3
(en)
|
2015-07-09 |
2024-06-24 |
Genmab As |
Bispecific and multispecific antibodies and method for isolating them
|
SI3319993T1
(en)
|
2015-07-10 |
2020-06-30 |
Genmab A/S |
Axl-specific antibody-drug conjugates for cancer treatment
|
NZ739028A
(en)
|
2015-07-15 |
2023-05-26 |
Genmab As |
Humanized or chimeric cd3 antibodies
|
GB201601073D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibodies
|
GB201601075D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibodies molecules
|
GB201601077D0
(en)
|
2016-01-20 |
2016-03-02 |
Ucb Biopharma Sprl |
Antibody molecule
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
EP3328418A1
(en)
|
2015-07-29 |
2018-06-06 |
Novartis AG |
Combination therapies comprising antibody molecules to pd-1
|
PL3317301T3
(en)
|
2015-07-29 |
2021-11-15 |
Novartis Ag |
Combination therapies comprising antibody molecules to lag-3
|
GEP20227419B
(en)
|
2015-07-30 |
2022-10-10 |
Macrogenics Inc |
Pd-1-binding molecules and methods of use thereof
|
EA201890434A1
(en)
|
2015-08-05 |
2018-10-31 |
Янссен Байотек, Инк. |
ANTIBODIES TO CD154 AND METHODS OF THEIR APPLICATION
|
AU2016308567B2
(en)
|
2015-08-17 |
2022-10-27 |
Janssen Biotech, Inc. |
Anti-BCMA antibodies, bispecific antigen binding molecules that bind BCMA and CD3, and uses thereof
|
CN116396393A
(en)
|
2015-10-08 |
2023-07-07 |
酵活英属哥伦比亚省公司 |
Antigen binding polypeptide constructs comprising kappa and lambda light chains and uses thereof
|
KR101851380B1
(en)
*
|
2015-10-12 |
2018-04-23 |
아주대학교산학협력단 |
Method to generate CH3 domain mutant pairs of heterodimeric Fc using yeast mating and CH3 domain mutant pairs thereby
|
WO2017067944A1
(en)
|
2015-10-19 |
2017-04-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the survival time of subjects suffering from triple negative breast cancer
|
BR112018008908A2
(en)
|
2015-11-02 |
2018-11-27 |
Janssen Pharmaceutica Nv |
anti-il1rap antibodies, bispecific antigen-binding molecules that bind il1rap and cd3, and their uses
|
KR20180069070A
(en)
|
2015-11-03 |
2018-06-22 |
얀센 바이오테크 인코포레이티드 |
Antibodies that specifically bind to TIM-3 and uses thereof
|
AU2016350717B2
(en)
|
2015-11-03 |
2023-08-10 |
Janssen Biotech, Inc. |
Subcutaneous formulations of anti-CD38 antibodies and their uses
|
US11649293B2
(en)
|
2015-11-18 |
2023-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Method for enhancing humoral immune response
|
JP6931329B2
(en)
|
2015-11-18 |
2021-09-01 |
中外製薬株式会社 |
Combination therapy using T cell redirection antigen-binding molecule for cells with immunosuppressive function
|
WO2017096276A1
(en)
*
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Anti-gitr antibodies and methods of use thereof
|
MA43389A
(en)
*
|
2015-12-02 |
2021-05-12 |
Agenus Inc |
ANTI-OX40 ANTIBODIES AND PROCESSES FOR USE
|
GB201521389D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Method
|
GB201521391D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Antibodies
|
GB201521393D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Antibodies
|
GB201521382D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl |
Antibodies
|
GB201521383D0
(en)
|
2015-12-03 |
2016-01-20 |
Ucb Biopharma Sprl And Ucb Celltech |
Method
|
CN108699136B
(en)
|
2015-12-07 |
2022-03-18 |
Xencor股份有限公司 |
Heterodimeric antibodies that bind CD3 and PSMA
|
BR112018011781A2
(en)
|
2015-12-14 |
2018-12-04 |
Macrogenics Inc |
bispecific molecule having one or more epitope binding sites capable of immunospecific binding to (one) pd-1 epitope (s) and one or more epitope binding sites capable of immunospecific binding to (one) epitope (s) -4, and pharmaceutical composition
|
US20200261573A1
(en)
|
2015-12-17 |
2020-08-20 |
Novartis Ag |
Combination of c-met inhibitor with antibody molecule to pd-1 and uses thereof
|
CN108495651A
(en)
|
2015-12-17 |
2018-09-04 |
诺华股份有限公司 |
The antibody molecule and application thereof of anti-PD-1
|
BR112018012344A2
(en)
|
2015-12-17 |
2018-12-04 |
Janssen Biotech Inc |
antibodies that specifically bind to hla-dr and their uses
|
JP7219005B2
(en)
|
2015-12-28 |
2023-02-07 |
中外製薬株式会社 |
Methods for Streamlining Purification of Fc Region-Containing Polypeptides
|
EP3851457A1
(en)
|
2016-01-21 |
2021-07-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
AU2017209099A1
(en)
|
2016-01-22 |
2018-08-02 |
Janssen Biotech, Inc. |
Anti-ROR1 antibodies, ROR1 x CD3 bispecific antibodies, and methods of using the same
|
EP4035681A1
(en)
|
2016-01-28 |
2022-08-03 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and pharmaceutical composition for the treatment of cancer
|
EP3419999B1
(en)
|
2016-02-26 |
2021-08-04 |
(INSERM) Institut National de la Santé et de la Recherche Médicale |
Antibodies having specificity for btla and uses thereof
|
US20200281973A1
(en)
|
2016-03-04 |
2020-09-10 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
TW202214700A
(en)
|
2016-03-14 |
2022-04-16 |
日商中外製藥股份有限公司 |
Cell injury inducing therapeutic drug for use in cancer therapy
|
CN114907483A
(en)
|
2016-03-22 |
2022-08-16 |
国家医疗保健研究所 |
Humanized anti-claudin-1antibodies and uses thereof
|
WO2017165683A1
(en)
|
2016-03-23 |
2017-09-28 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
KR20180134385A
(en)
|
2016-04-15 |
2018-12-18 |
노파르티스 아게 |
Compositions and methods for selective protein expression
|
JP7096770B2
(en)
|
2016-04-20 |
2022-07-06 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
Compositions and Methods for Producing Antibodies Based on the Use of Expression-Enhanced loci
|
BR112018071285A2
(en)
|
2016-04-20 |
2019-02-12 |
Regeneron Pharma |
cell, vector set, vector, system, and method
|
KR20190005998A
(en)
|
2016-05-18 |
2019-01-16 |
젠맵 비. 브이 |
Antibodies and Their Use in the Treatment of Infectious Diseases
|
WO2017202962A1
(en)
|
2016-05-24 |
2017-11-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of non small cell lung cancer (nsclc) that coexists with chronic obstructive pulmonary disease (copd)
|
US20210177896A1
(en)
|
2016-06-02 |
2021-06-17 |
Novartis Ag |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
EP4257613A3
(en)
|
2016-06-14 |
2023-12-13 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
WO2017223180A2
(en)
|
2016-06-21 |
2017-12-28 |
Janssen Biotech, Inc. |
Cysteine engineered fibronectin type iii domain binding molecules
|
JP2019527678A
(en)
|
2016-06-28 |
2019-10-03 |
ユーエムセー・ユトレヒト・ホールディング・ベー・フェー |
Treatment of IgE-mediated diseases with antibodies that specifically bind to CD38
|
EP3475304B1
(en)
|
2016-06-28 |
2022-03-23 |
Xencor, Inc. |
Heterodimeric antibodies that bind somatostatin receptor 2
|
CN107586336A
(en)
*
|
2016-07-09 |
2018-01-16 |
复旦大学 |
For the full human monoclonal antibody of zika virus and application
|
CA3030636A1
(en)
|
2016-07-14 |
2018-01-18 |
Genmab A/S |
Multispecific antibodies against cd40 and cd137
|
JP7219376B2
(en)
|
2016-07-15 |
2023-02-08 |
ノバルティス アーゲー |
Treatment and prevention of cytokine release syndrome using chimeric antigen receptors in combination with kinase inhibitors
|
TWI781108B
(en)
|
2016-07-20 |
2022-10-21 |
比利時商健生藥品公司 |
Anti- gprc5d antibodies, bispecific antigen binding molecules that bind gprc5d and cd3, and uses thereof
|
CN118021943A
(en)
|
2016-07-28 |
2024-05-14 |
诺华股份有限公司 |
Combination therapy of chimeric antigen receptor and PD-1 inhibitor
|
JP7219207B2
(en)
|
2016-07-29 |
2023-02-07 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
Antibodies targeting tumor-associated macrophages and uses thereof
|
EP3490590A2
(en)
|
2016-08-01 |
2019-06-05 |
Novartis AG |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
WO2018026942A1
(en)
*
|
2016-08-02 |
2018-02-08 |
Merrimack Pharmaceuticals, Inc. |
Heteromeric polypeptides
|
US10696722B2
(en)
|
2016-08-10 |
2020-06-30 |
Ajou University Industry-Academic Cooperation Foundation |
Heterodimeric Fc-fused cytokine and pharmaceutical composition comprising the same
|
KR102554331B1
(en)
|
2016-08-12 |
2023-07-10 |
얀센 바이오테크 인코포레이티드 |
Fc engineered anti-TNFR superfamily member antibodies with enhanced agonistic activity and methods of use thereof
|
CA3033661A1
(en)
|
2016-08-12 |
2018-02-15 |
Janssen Biotech, Inc. |
Engineered antibodies and other fc-domain containing molecules with enhanced agonism and effector functions
|
WO2018036947A1
(en)
|
2016-08-22 |
2018-03-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of inhibiting biological responses induced by a receptor that uses pi3k to signal in a cell
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
CN117866991A
(en)
|
2016-10-07 |
2024-04-12 |
诺华股份有限公司 |
Chimeric antigen receptor for the treatment of cancer
|
PE20191034A1
(en)
|
2016-10-14 |
2019-08-05 |
Xencor Inc |
BISPECIFIC HETERODIMERIC FUSION PROTEINS CONTAINING FC IL-15 / IL-15R FUSION PROTEINS AND PD-1 ANTIBODY FRAGMENTS
|
JOP20190095A1
(en)
|
2016-10-27 |
2019-04-28 |
Janssen Pharmaceutica Nv |
Cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide y receptors
|
BR112019008702A2
(en)
|
2016-11-01 |
2019-07-16 |
Genmab B.V. |
polypeptide, method of decreasing a polypeptide effector function, composition, method of treatment, kit of parts, and use of a polypeptide or composition.
|
CN109923128A
(en)
|
2016-11-15 |
2019-06-21 |
基因泰克公司 |
Administration for being treated with anti-CD20/ AntiCD3 McAb bispecific antibody
|
GB201619652D0
(en)
|
2016-11-21 |
2017-01-04 |
Alligator Bioscience Ab |
Novel polypeptides
|
US10287256B2
(en)
|
2016-11-23 |
2019-05-14 |
Immunogen, Inc. |
Selective sulfonation of benzodiazepine derivatives
|
BR112019012154A2
(en)
|
2016-12-14 |
2019-11-12 |
Janssen Biotech Inc |
cd8a-binding fibronectin type iii domains
|
US10611823B2
(en)
|
2016-12-14 |
2020-04-07 |
Hanssen Biotech, Inc |
CD137 binding fibronectin type III domains
|
WO2018111976A1
(en)
|
2016-12-14 |
2018-06-21 |
Janssen Biotech, Inc. |
Pd-l1 binding fibronectin type iii domains
|
EP4043485A1
(en)
|
2017-01-26 |
2022-08-17 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
SG11201907299XA
(en)
|
2017-02-08 |
2019-09-27 |
Dragonfly Therapeutics Inc |
Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
|
BR112019015900A2
(en)
|
2017-02-10 |
2020-04-07 |
Genmab B.V. |
polypeptide, methods to increase the agonistic activity of a polypeptide, to increase the cdc activity of a polypeptide and to treat an individual having a disease, composition, kit of parts, and, use of a polypeptide or composition
|
US10626169B2
(en)
|
2017-02-17 |
2020-04-21 |
Sanofi |
Multispecific binding molecules having specificity to dystroglycan and laminin-2
|
PT3583120T
(en)
|
2017-02-17 |
2022-12-15 |
Denali Therapeutics Inc |
Engineered transferrin receptor binding polypeptides
|
CA3053774A1
(en)
|
2017-02-17 |
2018-08-23 |
Sanofi |
Multispecific binding molecules having specificity to dystroglycan and laminin-2
|
ES2955074T3
(en)
|
2017-02-20 |
2023-11-28 |
Dragonfly Therapeutics Inc |
Proteins that bind to HER2, NKG2D and CD16
|
WO2018158719A1
(en)
|
2017-03-02 |
2018-09-07 |
Novartis Ag |
Engineered heterodimeric proteins
|
JP2020510432A
(en)
|
2017-03-02 |
2020-04-09 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
Antibodies with specificity for NECTIN-4 and uses thereof
|
MA49823A
(en)
|
2017-03-09 |
2021-04-21 |
Genmab As |
ANTIBODIES DIRECTED AGAINST PD-L1
|
AU2018242227A1
(en)
|
2017-03-31 |
2019-10-17 |
Genmab Holding B.V. |
Bispecific anti-CD37 antibodies, monoclonal anti-CD37 antibodies and methods of use thereof
|
CA3055769A1
(en)
|
2017-04-03 |
2018-10-11 |
Oncologie, Inc. |
Methods for treating cancer using ps-targeting antibodies with immuno-oncology agents
|
WO2018189403A1
(en)
|
2017-04-14 |
2018-10-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of cancer
|
US20200055948A1
(en)
|
2017-04-28 |
2020-02-20 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
EP3615068A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
US20200048358A1
(en)
|
2017-05-02 |
2020-02-13 |
Alligator Bioscience Ab |
Bispecific antibody against ox40 and ctla-4
|
KR102661320B1
(en)
|
2017-06-05 |
2024-05-03 |
얀센 바이오테크 인코포레이티드 |
Surface charge manipulation method for generating bispecific antibodies
|
PE20200294A1
(en)
|
2017-06-05 |
2020-02-05 |
Janssen Biotech Inc |
ANTIBODIES THAT SPECIFICALLY BIND PD-1 AND METHODS OF USE
|
CN111328335A
(en)
|
2017-06-07 |
2020-06-23 |
根马布私人有限公司 |
Therapeutic antibodies based on mutant IGG hexamers
|
UY37758A
(en)
|
2017-06-12 |
2019-01-31 |
Novartis Ag |
METHOD OF MANUFACTURING OF BIESPECTIFIC ANTIBODIES, BISPECTIFIC ANTIBODIES AND THERAPEUTIC USE OF SUCH ANTIBODIES
|
EP3642228A1
(en)
*
|
2017-06-21 |
2020-04-29 |
Gsbio, LLC |
Heterodimeric bispecific antibodies
|
EP3642229A1
(en)
|
2017-06-21 |
2020-04-29 |
Gilead Sciences, Inc. |
Multispecific antibodies that target hiv gp120 and cd3
|
CN118307674A
(en)
|
2017-06-22 |
2024-07-09 |
诺华股份有限公司 |
Antibody molecules against CD73 and uses thereof
|
EP3645037A1
(en)
|
2017-06-27 |
2020-05-06 |
Novartis AG |
Dosage regimens for anti-tim-3 antibodies and uses thereof
|
EP3645122A1
(en)
|
2017-06-30 |
2020-05-06 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and antigen binding domains
|
EP3675892A4
(en)
|
2017-07-03 |
2021-10-06 |
Torque Therapeutics, Inc. |
Immunostimulatory fusion molecules and uses thereof
|
NZ760841A
(en)
|
2017-07-11 |
2024-02-23 |
Compass Therapeutics Llc |
Agonist antibodies that bind human cd137 and uses thereof
|
KR20200031659A
(en)
|
2017-07-20 |
2020-03-24 |
노파르티스 아게 |
Dosage regimen of anti-LAG-3 antibody and use thereof
|
WO2019014912A1
(en)
*
|
2017-07-21 |
2019-01-24 |
赵磊 |
Heterodimeric protein and preparation method thereof
|
KR20200064062A
(en)
|
2017-08-04 |
2020-06-05 |
젠맵 에이/에스 |
Binders that bind to PD-L1 and CD137 and uses thereof
|
US10891219B1
(en)
|
2017-08-07 |
2021-01-12 |
Electronic Arts Inc. |
Code failure prediction system
|
EP3672986A1
(en)
|
2017-08-22 |
2020-07-01 |
Sanabio, LLC |
Soluble interferon receptors and uses thereof
|
EP3457139A1
(en)
|
2017-09-19 |
2019-03-20 |
Promise Advanced Proteomics |
Antibody-like peptides for quantifying therapeutic antibodies
|
US11572409B2
(en)
|
2017-09-21 |
2023-02-07 |
Imcheck Therapeutics Sas |
Antibodies having specificity for BTN2 and uses thereof
|
CA3078157A1
(en)
|
2017-10-20 |
2019-04-25 |
F.Hoffmann-La Roche Ag |
Method for generating multispecific antibodies from monospecific antibodies
|
CN111372947A
(en)
|
2017-10-30 |
2020-07-03 |
豪夫迈·罗氏有限公司 |
Method for generating multispecific antibodies from monospecific antibodies in vivo
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
JP2021502100A
(en)
|
2017-11-08 |
2021-01-28 |
ゼンコア インコーポレイテッド |
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
WO2019099838A1
(en)
|
2017-11-16 |
2019-05-23 |
Novartis Ag |
Combination therapies
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
EP3713959A1
(en)
*
|
2017-11-21 |
2020-09-30 |
Innate Pharma |
Multispecific antigen binding proteins
|
WO2019106126A1
(en)
|
2017-12-01 |
2019-06-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Mdm2 modulators for the diagnosis and treatment of liposarcoma
|
EP3498293A1
(en)
|
2017-12-15 |
2019-06-19 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Treatment of monogenic diseases with an anti-cd45rc antibody
|
AU2018390418B2
(en)
|
2017-12-19 |
2023-12-21 |
Xencor, Inc. |
Engineered IL-2 Fc fusion proteins
|
US11667713B2
(en)
|
2017-12-28 |
2023-06-06 |
Chugai Seiyaku Kabushiki Kaisha |
Cytotoxicity-inducing therapeutic agent
|
US11067584B2
(en)
|
2018-01-12 |
2021-07-20 |
Genzyme Corporation |
Methods for the quantitation of polypeptides
|
JP2021510740A
(en)
|
2018-01-24 |
2021-04-30 |
ゲンマブ ビー.ブイ. |
Polypeptide variants and their uses
|
AU2019215031A1
(en)
|
2018-01-31 |
2020-08-20 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
WO2019157366A1
(en)
|
2018-02-08 |
2019-08-15 |
Dragonfly Therapeutics, Inc. |
Antibody variable domains targeting the nkg2d receptor
|
US11866498B2
(en)
|
2018-02-08 |
2024-01-09 |
Genentech, Inc. |
Bispecific antigen-binding molecules and methods of use
|
BR112020015052A2
(en)
|
2018-02-09 |
2020-12-08 |
Genmab A/S |
PHARMACEUTICAL COMPOSITION, USE OF THE PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING CANCER IN A SUBJECT, TO PREPARE A PHARMACEUTICAL COMPOSITION AND TO PREPARE A UNIT DOSAGE FORM, UNIT DOSAGE FORM, CONTAINER, AND, KIT-PARTIES
|
JP2018138022A
(en)
*
|
2018-02-23 |
2018-09-06 |
ゲンマブ ビー.ブイ. |
Human igg1 fc region variants and uses thereof
|
CA3093745A1
(en)
|
2018-03-12 |
2019-09-19 |
Genmab A/S |
Antibodies
|
KR20200132919A
(en)
*
|
2018-03-14 |
2020-11-25 |
아피메트 게엠베하 |
Bispecific EGFR/CD16 antigen-binding protein
|
EP3773911A2
(en)
|
2018-04-04 |
2021-02-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
EP3775908A1
(en)
|
2018-04-13 |
2021-02-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting outcome and treatment of patients suffering from prostate cancer or breast cancer
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
AU2019256539A1
(en)
|
2018-04-18 |
2020-11-26 |
Xencor, Inc. |
PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof
|
EP3781598A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
WO2019207030A1
(en)
|
2018-04-26 |
2019-10-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting a response with an immune checkpoint inhibitor in a patient suffering from a lung cancer
|
US20210047405A1
(en)
|
2018-04-27 |
2021-02-18 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
BR112020022179A2
(en)
|
2018-05-03 |
2021-02-02 |
Genmab B.V. |
first antibody, antibody, composition, methods for treating an individual having a disease, for depleting a cell population and for inducing proliferation in a cell population, and, kit.
|
CA3100118A1
(en)
|
2018-05-16 |
2019-11-21 |
Janssen Biotech, Inc. |
Bcma/cd3 and gprdc5d/cd3 bispecific antibodies for use in cancer therapy
|
WO2019226617A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Compositions and methods for enhancing the killing of target cells by nk cells
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
SG11202011633SA
(en)
|
2018-05-24 |
2020-12-30 |
Janssen Biotech Inc |
Psma binding agents and uses thereof
|
CN112703203A
(en)
|
2018-05-24 |
2021-04-23 |
詹森生物科技公司 |
Monospecific and multispecific anti-TMEF 2 antibodies and uses thereof
|
JOP20190116A1
(en)
|
2018-05-24 |
2019-11-24 |
Janssen Biotech Inc |
Anti-cd33 antibodies, anti-cd33/anti-cd3 bispecific antibodies and uses thereof
|
PE20210132A1
(en)
|
2018-05-24 |
2021-01-19 |
Janssen Biotech Inc |
ANTI-CD3 ANTIBODIES AND USES OF THEM
|
US20210213063A1
(en)
|
2018-05-25 |
2021-07-15 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
JP7398396B2
(en)
|
2018-06-01 |
2023-12-14 |
ノバルティス アーゲー |
Binding molecules for BCMA and their uses
|
JP2021525087A
(en)
|
2018-06-01 |
2021-09-24 |
コンピュジェン リミテッド |
Anti-PVRIG / anti-TIGIT bispecific antibody and usage
|
AU2019284911A1
(en)
|
2018-06-13 |
2020-12-17 |
Novartis Ag |
BCMA chimeric antigen receptors and uses thereof
|
WO2019246293A2
(en)
|
2018-06-19 |
2019-12-26 |
Atarga, Llc |
Antibody molecules to complement component 5 and uses thereof
|
WO2019243636A1
(en)
|
2018-06-22 |
2019-12-26 |
Genmab Holding B.V. |
Anti-cd37 antibodies and anti-cd20 antibodies, compositions and methods of use thereof
|
WO2019243626A1
(en)
|
2018-06-22 |
2019-12-26 |
Genmab A/S |
Method for producing a controlled mixture of two or more different antibodies
|
AR116109A1
(en)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
DERIVATIVES OF 3- (5-AMINO-1-OXOISOINDOLIN-2-IL) PIPERIDINE-2,6-DIONA AND USES OF THE SAME
|
MA53123A
(en)
|
2018-07-13 |
2021-05-19 |
Genmab As |
TROGOCYTOSIS MEDIATION THERAPY USING CD38 ANTIBODIES
|
SG11202012993SA
(en)
|
2018-07-13 |
2021-02-25 |
Genmab As |
Variants of cd38 antibody and uses thereof
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
CA3155293A1
(en)
|
2018-09-24 |
2020-04-02 |
The Medical College Of Wisconsin, Inc. |
System and method for the development of cd30 bispecific antibodies for immunotherapy of cd30+ malignancies
|
WO2020067541A1
(en)
*
|
2018-09-28 |
2020-04-02 |
協和キリン株式会社 |
Antibody composition
|
WO2020070062A1
(en)
|
2018-10-01 |
2020-04-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of tim-3 inhibitors for the treatment of exacerbations in patients suffering from severe asthma
|
AU2019355971A1
(en)
|
2018-10-03 |
2021-05-06 |
Xencor, Inc. |
IL-12 heterodimeric Fc-fusion proteins
|
CN113365698A
(en)
|
2018-10-04 |
2021-09-07 |
健玛保控股有限公司 |
Pharmaceutical compositions comprising bispecific anti-CD 37 antibodies
|
CN113423734A
(en)
|
2018-10-12 |
2021-09-21 |
Xencor股份有限公司 |
PD-1 targeted IL-15/IL-15R alpha FC fusion protein and application thereof in combination therapy
|
WO2020086758A1
(en)
*
|
2018-10-23 |
2020-04-30 |
Dragonfly Therapeutics, Inc. |
Heterodimeric fc-fused proteins
|
CA3118789A1
(en)
|
2018-11-06 |
2020-05-14 |
Genmab A/S |
Antibody formulation
|
US20220025058A1
(en)
|
2018-11-06 |
2022-01-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of acute myeloid leukemia by eradicating leukemic stem cells
|
CA3119161A1
(en)
|
2018-11-13 |
2020-05-22 |
Compass Therapeutics Llc |
Multispecific binding constructs against checkpoint molecules and uses thereof
|
EP3897853A1
(en)
|
2018-12-20 |
2021-10-27 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
BR112021011874A2
(en)
|
2018-12-20 |
2021-09-08 |
Novartis Ag |
DOSAGE SCHEME AND PHARMACEUTICAL COMBINATION INCLUDING DERIVATIVES OF 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE
|
WO2020128894A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Combinations of a hdm2-p53 interaction inhibitor and a bcl2 inhibitor and their use for treating cancer
|
WO2020136564A1
(en)
|
2018-12-24 |
2020-07-02 |
Sanofi |
Pseudofab-based multispecific binding proteins
|
WO2020141199A1
(en)
|
2019-01-03 |
2020-07-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for enhancing cd8+ t cell-dependent immune responses in subjects suffering from cancer
|
TW202043256A
(en)
|
2019-01-10 |
2020-12-01 |
美商健生生物科技公司 |
Prostate neoantigens and their uses
|
MX2021008537A
(en)
|
2019-01-15 |
2021-11-12 |
Janssen Biotech Inc |
Anti-tnf antibody compositions and methods for the treatment of juvenile idiopathic arthritis.
|
BR112021013824A2
(en)
|
2019-01-18 |
2021-12-14 |
Janssen Biotech Inc |
gprc5d chimeric antigen receptors and cells expressing the same
|
KR20210118878A
(en)
|
2019-01-23 |
2021-10-01 |
얀센 바이오테크 인코포레이티드 |
Anti-TNF antibody composition for use in a method of treating psoriatic arthritis
|
CN113329792B
(en)
|
2019-02-15 |
2024-06-28 |
诺华股份有限公司 |
Substituted 3- (1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof
|
CN113490528A
(en)
|
2019-02-15 |
2021-10-08 |
诺华股份有限公司 |
3- (1-oxo-5- (piperidine-4-yl) isoindoline-2-yl) piperidine-2, 6-dione derivatives and uses thereof
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
EP3927371A1
(en)
|
2019-02-22 |
2021-12-29 |
Novartis AG |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
KR20210132117A
(en)
|
2019-02-26 |
2021-11-03 |
얀센 바이오테크 인코포레이티드 |
Combination Therapy and Patient Stratification Using Bispecific Anti-EGFR/c-Met Antibodies
|
CA3132185A1
(en)
|
2019-03-01 |
2020-09-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
MA55305A
(en)
|
2019-03-11 |
2022-01-19 |
Janssen Biotech Inc |
ANTI-V BETA 17/ANTI-CD123 BISPECIFIC ANTIBODIES
|
US20220153829A1
(en)
|
2019-03-14 |
2022-05-19 |
Janssen Biotech, Inc. |
Methods for Producing Anti-TNF Antibody Compositions
|
EP3938384A4
(en)
|
2019-03-14 |
2022-12-28 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-il12/il23 antibody compositions
|
JP2022526881A
(en)
|
2019-03-14 |
2022-05-27 |
ヤンセン バイオテツク,インコーポレーテツド |
Methods for Producing Anti-TNF Antibody Compositions
|
MA55282A
(en)
|
2019-03-14 |
2022-01-19 |
Janssen Biotech Inc |
MANUFACTURING METHODS FOR THE PRODUCTION OF ANTI-TNF ANTIBODY COMPOSITIONS
|
WO2020188086A1
(en)
|
2019-03-20 |
2020-09-24 |
Imcheck Therapeutics Sas |
Antibodies having specificity for btn2 and uses thereof
|
CA3135430A1
(en)
|
2019-03-29 |
2020-10-08 |
Atarga, Llc |
Anti fgf23 antibody
|
CN113747944A
(en)
|
2019-04-19 |
2021-12-03 |
詹森生物科技公司 |
Methods of treating prostate cancer with anti-PSMA/CD 3 antibodies
|
AU2020267504A1
(en)
|
2019-05-08 |
2021-12-02 |
Janssen Biotech, Inc. |
Materials and methods for modulating T cell mediated immunity
|
WO2020225456A1
(en)
|
2019-05-09 |
2020-11-12 |
Genmab B.V. |
Dosage regimens for a combination of anti-dr5 antibodies for use in treating cancer
|
WO2020230091A1
(en)
|
2019-05-14 |
2020-11-19 |
Janssen Biotech, Inc. |
Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors
|
MX2021013955A
(en)
*
|
2019-05-14 |
2022-03-11 |
Janssen Biotech Inc |
Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors.
|
WO2020236797A1
(en)
|
2019-05-21 |
2020-11-26 |
Novartis Ag |
Variant cd58 domains and uses thereof
|
AU2020279974A1
(en)
|
2019-05-21 |
2021-11-18 |
Novartis Ag |
CD19 binding molecules and uses thereof
|
CN114173810A
(en)
|
2019-05-21 |
2022-03-11 |
诺华股份有限公司 |
Trispecific binding molecules directed against BCMA and uses thereof
|
WO2020243477A2
(en)
|
2019-05-30 |
2020-12-03 |
Amgen Inc. |
Engineering the hinge region to drive antibody dimerization
|
WO2020245676A1
(en)
|
2019-06-03 |
2020-12-10 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions, and methods for the treatment of psoriatic arthritis
|
EP4023230A4
(en)
|
2019-06-05 |
2023-11-15 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody cleavage site-binding molecule
|
CN113950485A
(en)
|
2019-07-10 |
2022-01-18 |
中外制药株式会社 |
Claudin-6 binding molecules and uses thereof
|
US20220275069A1
(en)
|
2019-07-12 |
2022-09-01 |
Janssen Pharmaceutica Nv |
Binding agents and uses thereof
|
EP3999540A1
(en)
|
2019-07-16 |
2022-05-25 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Antibodies having specificity for cd38 and uses thereof
|
KR20220040483A
(en)
|
2019-07-26 |
2022-03-30 |
얀센 바이오테크 인코포레이티드 |
Proteins comprising kallikrein-associated peptidase 2 antigen binding domains and uses thereof
|
MX2022001882A
(en)
|
2019-08-12 |
2022-05-30 |
Aptevo Res & Development Llc |
4-1bb and ox40 binding proteins and related compositions and methods, antibodies against 4-1bb, antibodies against ox40.
|
WO2021030657A1
(en)
|
2019-08-15 |
2021-02-18 |
Janssen Biotech, Inc. |
Materials and methods for improved single chain variable fragments
|
WO2021028587A1
(en)
|
2019-08-15 |
2021-02-18 |
Genmab A/S |
Pharmaceutical compositions comprising bispecific antibodies directed against cd3 and cd20 and their uses
|
WO2021048423A1
(en)
|
2019-09-12 |
2021-03-18 |
Genmab A/S |
Bispecific antibodies binding to 5t4 and cd3 for use in treatment of cancer
|
WO2021058729A1
(en)
|
2019-09-27 |
2021-04-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Anti-müllerian inhibiting substance type i receptor antibodies and uses thereof
|
EP3800201A1
(en)
|
2019-10-01 |
2021-04-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Cd28h stimulation enhances nk cell killing activities
|
TW202128757A
(en)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
Pd-1 targeted il-15/il-15ralpha fc fusion proteins with improved properties
|
EP4045061A4
(en)
|
2019-10-14 |
2024-04-17 |
ARO Biotherapeutics Company |
Cd71 binding fibronectin type iii domains
|
WO2021076574A2
(en)
|
2019-10-14 |
2021-04-22 |
Aro Biotherapeutics Company |
Fn3 domain-sirna conjugates and uses thereof
|
JP2022553306A
(en)
|
2019-10-21 |
2022-12-22 |
ノバルティス アーゲー |
TIM-3 inhibitors and uses thereof
|
MX2022004766A
(en)
|
2019-10-21 |
2022-05-16 |
Novartis Ag |
Combination therapies with venetoclax and tim-3 inhibitors.
|
JP2023500701A
(en)
|
2019-11-06 |
2023-01-10 |
ジェンマブ ビー.ブイ. |
Antibody variant combinations and uses thereof
|
CA3161825A1
(en)
|
2019-11-18 |
2021-05-27 |
Janssen Biotech, Inc. |
Anti-cd79 chimeric antigen receptors, car-t cells, and uses thereof
|
BR112022010206A2
(en)
|
2019-11-26 |
2022-11-29 |
Novartis Ag |
CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF
|
US20230040928A1
(en)
|
2019-12-09 |
2023-02-09 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies having specificity to her4 and uses thereof
|
JP2023506750A
(en)
|
2019-12-11 |
2023-02-20 |
シラグ・ゲーエムベーハー・インターナショナル |
Multispecific binding molecules comprising LTBR and EDB binding domains and uses thereof
|
AU2020403145A1
(en)
|
2019-12-13 |
2022-07-07 |
Genentech, Inc. |
Anti-Ly6G6D antibodies and methods of use
|
GB201919062D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Antibody
|
GB201919061D0
(en)
|
2019-12-20 |
2020-02-05 |
Ucb Biopharma Sprl |
Multi-specific antibody
|
CA3165399A1
(en)
|
2019-12-20 |
2021-06-24 |
Novartis Ag |
Uses of anti-tgf-beta antibodies and checkpoint inhibitors for the treatment of proliferative diseases
|
JP7373588B2
(en)
|
2019-12-27 |
2023-11-02 |
中外製薬株式会社 |
Anti-CTLA-4 antibody and its use
|
CN114980927A
(en)
|
2020-01-16 |
2022-08-30 |
健玛保 |
Formulations of CD38 antibodies and uses thereof
|
CN111239406B
(en)
*
|
2020-01-17 |
2023-06-30 |
王兰珍 |
Hepatocyte growth factor latex immunonephelometry detection kit and application thereof
|
CN115298322A
(en)
|
2020-01-17 |
2022-11-04 |
贝克顿迪金森公司 |
Methods and compositions for single cell secretogomics
|
MX2022008763A
(en)
|
2020-01-17 |
2022-07-27 |
Novartis Ag |
Combination comprising a tim-3 inhibitor and a hypomethylating agent for use in treating myelodysplastic syndrome or chronic myelomonocytic leukemia.
|
JP2023512071A
(en)
|
2020-01-30 |
2023-03-23 |
ウモジャ バイオファーマ, インコーポレイテッド |
Bispecific transduction enhancer
|
GB202001447D0
(en)
|
2020-02-03 |
2020-03-18 |
Ucb Biopharma Sprl |
Antibodies
|
WO2021155916A1
(en)
|
2020-02-04 |
2021-08-12 |
BioNTech SE |
Treatment involving antigen vaccination and binding agents binding to pd-l1 and cd137
|
BR112022015151A2
(en)
|
2020-02-04 |
2022-12-20 |
Genmab As |
METHOD FOR REDUCING OR PREVENTING PROGRESSION OF A TUMOR OR TREATING CANCER, AND, COMPOSITION
|
TW202144388A
(en)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
Neoantigens expressed in ovarian cancer and their uses
|
TW202144389A
(en)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
Neoantigens expressed in multiple myeloma and their uses
|
WO2021165488A1
(en)
|
2020-02-21 |
2021-08-26 |
Genmab B.V. |
Methods for the quantification of glycoproteins
|
CN115397460A
(en)
|
2020-02-27 |
2022-11-25 |
诺华股份有限公司 |
Methods of making cells expressing chimeric antigen receptors
|
EP4112642A4
(en)
|
2020-02-28 |
2024-06-26 |
Shanghai Henlius Biotech, Inc. |
Anti-cd137 construct and use thereof
|
WO2021170071A1
(en)
|
2020-02-28 |
2021-09-02 |
Shanghai Henlius Biotech, Inc. |
Anti-cd137 constructs, multispecific antibody and uses thereof
|
WO2021175954A1
(en)
|
2020-03-04 |
2021-09-10 |
Imcheck Therapeutics Sas |
Antibodies having specificity for btnl8 and uses thereof
|
US20230126689A1
(en)
|
2020-03-06 |
2023-04-27 |
Go Therapeutics, Inc. |
Anti-glyco-cd44 antibodies and their uses
|
EP4117715A1
(en)
|
2020-03-13 |
2023-01-18 |
Janssen Biotech, Inc. |
Materials and methods for binding siglec-3/cd33
|
JP2023517753A
(en)
|
2020-03-18 |
2023-04-26 |
ジェンマブ エー/エス |
Antibody that binds to B7H4
|
CN116249549A
(en)
|
2020-03-27 |
2023-06-09 |
诺华股份有限公司 |
Bispecific combination therapies for the treatment of proliferative diseases and autoimmune disorders
|
US11179644B2
(en)
|
2020-03-30 |
2021-11-23 |
Electronic Arts Inc. |
Videogame telemetry data and game asset tracker for session recordings
|
WO2021200857A1
(en)
|
2020-03-30 |
2021-10-07 |
国立大学法人三重大学 |
Bispecific antibody
|
CA3173519A1
(en)
|
2020-03-31 |
2021-10-07 |
Vishnu Priyanka Reddy CHICHILI |
Method for producing multispecific antigen-binding molecules
|
BR112022020753A2
(en)
|
2020-04-15 |
2022-12-20 |
Voyager Therapeutics Inc |
TAU-BINDING COMPOUNDS
|
CN115916840A
(en)
|
2020-04-16 |
2023-04-04 |
詹森生物科技公司 |
Systems, materials, and methods for reversed-phase high performance liquid chromatography (RP-HPLC) for monitoring formation of multispecific molecules
|
IL297545A
(en)
|
2020-04-26 |
2022-12-01 |
Biocytogen Pharmaceuticals Beijing Co Ltd |
Modified immunoglobulins
|
US11446570B2
(en)
|
2020-05-08 |
2022-09-20 |
Electronic Arts Inc. |
Automated test multiplexing system
|
KR20230008775A
(en)
|
2020-05-08 |
2023-01-16 |
젠맵 에이/에스 |
Bispecific antibodies to CD3 and CD20
|
BR112022022800A2
(en)
|
2020-05-11 |
2022-12-13 |
Janssen Biotech Inc |
METHODS FOR TREATMENT OF MULTIPLE MYELOMA
|
JP2023525053A
(en)
|
2020-05-12 |
2023-06-14 |
インサーム(インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル) |
A new method to treat cutaneous T-cell lymphoma and TFH-derived lymphoma
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
CN115551896A
(en)
*
|
2020-05-15 |
2022-12-30 |
神州细胞工程有限公司 |
Method for enhancing antigen immunogenicity by forming Fc fragment fusion protein glycoconjugates
|
JP7048665B2
(en)
*
|
2020-05-22 |
2022-04-05 |
ゲンマブ ビー.ブイ. |
Human IgG1 Fc region mutant and its use
|
EP4157459A1
(en)
|
2020-05-27 |
2023-04-05 |
Janssen Biotech, Inc. |
Proteins comprising cd3 antigen binding domains and uses thereof
|
GB202008860D0
(en)
|
2020-06-11 |
2020-07-29 |
Univ Oxford Innovation Ltd |
BTLA antibodies
|
CA3182346A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
WO2022013787A1
(en)
|
2020-07-16 |
2022-01-20 |
Novartis Ag |
Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules
|
WO2022018294A1
(en)
|
2020-07-23 |
2022-01-27 |
Genmab B.V. |
A combination of anti-dr5 antibodies and an immunomodulatory imide drug for use in treating multiple myeloma
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
EP4188439A2
(en)
|
2020-07-29 |
2023-06-07 |
Janssen Biotech, Inc. |
Proteins comprising hla-g antigen binding domains and their uses
|
KR20230048059A
(en)
|
2020-07-31 |
2023-04-10 |
추가이 세이야쿠 가부시키가이샤 |
Pharmaceutical composition comprising cells expressing chimeric receptors
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
EP4192859A1
(en)
|
2020-08-06 |
2023-06-14 |
BioNTech SE |
Binding agents for coronavirus s protein
|
KR102607909B1
(en)
|
2020-08-19 |
2023-12-01 |
젠코어 인코포레이티드 |
Anti-CD28 composition
|
JP2023538897A
(en)
|
2020-08-20 |
2023-09-12 |
アムジエン・インコーポレーテツド |
Antigen binding proteins with non-canonical disulfides in the Fab region
|
JPWO2022044248A1
(en)
|
2020-08-28 |
2022-03-03 |
|
|
US20230338587A1
(en)
|
2020-08-31 |
2023-10-26 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
EP4204021A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
CN116472060A
(en)
|
2020-09-02 |
2023-07-21 |
健玛保 |
Antibody therapy
|
EP4210744A1
(en)
|
2020-09-10 |
2023-07-19 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
CA3189883A1
(en)
|
2020-09-10 |
2022-03-17 |
Brian Elliott |
Bispecific antibody against cd3 and cd20 in combination therapy for treating follicular lymphoma
|
EP4210747A1
(en)
|
2020-09-10 |
2023-07-19 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
BR112023004327A2
(en)
|
2020-09-10 |
2023-04-04 |
Genmab As |
METHOD TO TREAT CHRONIC LYMPHOCYTIC LEUKEMIA IN A HUMAN SUBJECT
|
BR112023004351A2
(en)
|
2020-09-10 |
2023-04-04 |
Genmab As |
METHOD TO TREAT FOLLICULAR LYMPHOMA IN A HUMAN SUBJECT
|
KR20230066392A
(en)
|
2020-09-10 |
2023-05-15 |
젠맵 에이/에스 |
Bispecific antibodies to CD3 and CD20 in combination therapy for the treatment of diffuse large B-cell lymphoma
|
US11965024B2
(en)
|
2020-09-11 |
2024-04-23 |
Janssen Biotech, Inc. |
Methods and compositions for modulating beta chain mediated immunity
|
US20230365714A1
(en)
|
2020-10-02 |
2023-11-16 |
Genmab A/S |
Antibodies capable of binding to ror2 and bispecific antibodies binding to ror2 and cd3
|
JP2023544769A
(en)
|
2020-10-07 |
2023-10-25 |
アムジエン・インコーポレーテツド |
Rational selection of building blocks for the construction of multispecific antibodies
|
EP4228693A1
(en)
|
2020-10-13 |
2023-08-23 |
Janssen Biotech, Inc. |
Bioengineered t cell mediated immunity, materials and other methods for modulating cluster of differentiation iv &/or viii
|
WO2022079199A1
(en)
|
2020-10-15 |
2022-04-21 |
UCB Biopharma SRL |
Binding molecules that multimerise cd45
|
TW202233672A
(en)
|
2020-10-22 |
2022-09-01 |
美商健生生物科技公司 |
Proteins comprising delta-like ligand 3 (dll3) antigen binding regions and their uses
|
IL302412A
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Anti-cd19 agent and b cell targeting agent combination therapy for treating b cell malignancies
|
JP2023547499A
(en)
|
2020-11-06 |
2023-11-10 |
ノバルティス アーゲー |
Antibody Fc variant
|
EP4240491A1
(en)
|
2020-11-06 |
2023-09-13 |
Novartis AG |
Cd19 binding molecules and uses thereof
|
TW202233663A
(en)
|
2020-11-10 |
2022-09-01 |
美商安進公司 |
Novel linkers of multispecific antigen binding domains
|
AU2021378316A1
(en)
|
2020-11-13 |
2023-06-01 |
Novartis Ag |
Combination therapies with chimeric antigen receptor (car)-expressing cells
|
AU2021390501A1
(en)
|
2020-12-01 |
2023-06-29 |
Aptevo Research And Development Llc |
Heterodimeric psma and cd3-binding bispecific antibodies
|
IL303294A
(en)
|
2020-12-07 |
2023-07-01 |
UCB Biopharma SRL |
Antibodies against interleukin-22
|
IL303295A
(en)
|
2020-12-07 |
2023-07-01 |
UCB Biopharma SRL |
Multi-specific antibodies and antibody combinations
|
KR20230128482A
(en)
|
2020-12-07 |
2023-09-05 |
젠맵 에이/에스 |
Combination therapy of antibodies and taxanes
|
KR20230137393A
(en)
|
2021-01-28 |
2023-10-04 |
얀센 바이오테크 인코포레이티드 |
PSMA binding protein and its uses
|
WO2022162569A1
(en)
|
2021-01-29 |
2022-08-04 |
Novartis Ag |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
BR112023016121A2
(en)
|
2021-02-16 |
2023-11-28 |
Janssen Pharmaceutica Nv |
TRIESPECIFIC ANTIBODY TARGETING BCMA, GPRC5D AND CD3
|
AU2022224508A1
(en)
|
2021-02-16 |
2023-10-05 |
Janssen Biotech, Inc. |
Materials and methods for enhanced linker targeting
|
WO2022187591A1
(en)
|
2021-03-05 |
2022-09-09 |
Go Therapeutics, Inc. |
Anti-glyco-cd44 antibodies and their uses
|
IL305736A
(en)
|
2021-03-09 |
2023-11-01 |
Xencor Inc |
Heterodimeric antibodies that bind cd3 and cldn6
|
BR112023018278A2
(en)
|
2021-03-09 |
2023-10-31 |
Janssen Biotech Inc |
TREATMENT OF CANCERS WITHOUT EGFR ACTIVATING MUTATIONS
|
CA3211334A1
(en)
|
2021-03-09 |
2022-09-15 |
Yali FU |
Multispecific binding agents against cd40 and cd137 in therapy
|
EP4305065A1
(en)
|
2021-03-10 |
2024-01-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
BR112023017887A2
(en)
|
2021-03-12 |
2023-10-10 |
Genmab As |
PROTEIN COMPRISING A FIRST POLYPEPTIDE AND A SECOND POLYPEPTIDE, BIESPECIFIC ANTIBODY, NUCLEIC ACID ENCODING SAID FIRST OR SECOND POLYPEPTIDE, HOST CELL, PHARMACEUTICAL COMPOSITION, PROTEIN, BIESPECIFIC ANTIBODY OR PHARMACEUTICAL COMPOSITION FOR US THE, AND, METHODS OF TREATMENT AND PREPARATION OF A BIESPECIFIC ANTIBODY
|
WO2022201053A1
(en)
|
2021-03-24 |
2022-09-29 |
Janssen Biotech, Inc. |
Proteins comprising cd3 antigen binding domains and uses thereof
|
BR112023019484A2
(en)
|
2021-03-24 |
2023-12-05 |
Janssen Biotech Inc |
TRIESPECIFIC ANTIBODY THAT TARGETS CD79B, CD20 AND CD3
|
AU2022244453A1
(en)
|
2021-03-24 |
2023-11-09 |
Janssen Biotech, Inc. |
Antibody targeting cd22 and cd79b
|
TW202304979A
(en)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
USES OF ANTI-TGFβ ANTIBODIES AND OTHER THERAPEUTIC AGENTS FOR THE TREATMENT OF PROLIFERATIVE DISEASES
|
WO2022219080A1
(en)
|
2021-04-14 |
2022-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve nk cells cytotoxicity
|
WO2022219076A1
(en)
|
2021-04-14 |
2022-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method to improve the anti-tumoral activity of macrophages
|
TW202308689A
(en)
*
|
2021-04-21 |
2023-03-01 |
美商健生生物科技公司 |
High concentration bispecific antibody formulations
|
CA3218933A1
(en)
|
2021-05-03 |
2022-11-10 |
UCB Biopharma SRL |
Antibodies
|
BR112023021089A2
(en)
|
2021-05-07 |
2023-12-12 |
Genmab As |
PHARMACEUTICAL COMPOSITION, METHOD FOR TREATING A DISEASE, METHOD FOR TREATING CANCER IN AN INDIVIDUAL, USE OF THE PHARMACEUTICAL COMPOSITION, UNIT DOSAGE FORM, KIT OF PARTS, AND, METHOD FOR PREPARING A PHARMACEUTICAL COMPOSITION
|
AR125874A1
(en)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
COMBINATION THERAPIES
|
TW202309094A
(en)
|
2021-05-18 |
2023-03-01 |
美商健生生物科技公司 |
Methods for identifying cancer patients for combination treatment
|
KR20240017912A
(en)
|
2021-06-04 |
2024-02-08 |
암젠 인크 |
Anti-CCR8 antibodies and uses thereof
|
CA3218481A1
(en)
|
2021-06-14 |
2022-12-22 |
argenx BV |
Anti-il-9 antibodies and methods of use thereof
|
TW202315891A
(en)
|
2021-06-21 |
2023-04-16 |
丹麥商珍美寶股份有限公司 |
Binding agent dosing schedule
|
CN117616123A
(en)
|
2021-06-25 |
2024-02-27 |
中外制药株式会社 |
anti-CTLA-4 antibodies
|
CA3220353A1
(en)
|
2021-06-25 |
2022-12-29 |
Chugai Seiyaku Kabushiki Kaisha |
Use of anti-ctla-4 antibody
|
IL309996A
(en)
|
2021-07-09 |
2024-03-01 |
Janssen Biotech Inc |
Manufacturing methods for producing anti-tnf antibody compositions
|
AU2022306144A1
(en)
|
2021-07-09 |
2024-02-22 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-tnf antibody compositions
|
CN117916260A
(en)
|
2021-07-09 |
2024-04-19 |
詹森生物科技公司 |
Methods of manufacture for preparing anti-IL 12/IL23 antibody compositions
|
IL309831A
(en)
|
2021-07-13 |
2024-02-01 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
CA3228178A1
(en)
|
2021-08-05 |
2023-02-09 |
Go Therapeutics, Inc. |
Anti-glyco-muc4 antibodies and their uses
|
GB202111905D0
(en)
|
2021-08-19 |
2021-10-06 |
UCB Biopharma SRL |
Antibodies
|
AU2022339819A1
(en)
|
2021-09-03 |
2024-04-11 |
Go Therapeutics, Inc. |
Anti-glyco-lamp1 antibodies and their uses
|
TW202328188A
(en)
|
2021-09-03 |
2023-07-16 |
美商Go治療公司 |
Anti-glyco-cmet antibodies and their uses
|
KR20240051280A
(en)
|
2021-09-06 |
2024-04-19 |
젠맵 에이/에스 |
Antibodies capable of binding CD27, variants thereof and uses thereof
|
CA3229822A1
(en)
|
2021-09-13 |
2023-03-16 |
Patrick John DOONAN |
Cd33 x v?2 multispecific antibodies for the treatment of cancer
|
WO2023044483A2
(en)
|
2021-09-20 |
2023-03-23 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
WO2023046322A1
(en)
|
2021-09-24 |
2023-03-30 |
Janssen Pharmaceutica Nv |
Proteins comprising cd20 binding domains, and uses thereof
|
JPWO2023053282A1
(en)
|
2021-09-29 |
2023-04-06 |
|
|
IL311805A
(en)
|
2021-10-08 |
2024-05-01 |
Genmab As |
Antibodies binding to cd30 and cd3
|
JPWO2023058723A1
(en)
|
2021-10-08 |
2023-04-13 |
|
|
GB202115122D0
(en)
|
2021-10-21 |
2021-12-08 |
Dualyx Nv |
Binding molecules targeting IL-2 receptor
|
WO2023077155A1
(en)
|
2021-11-01 |
2023-05-04 |
Janssen Biotech, Inc. |
Compositions and methods for the modulation of beta chain-mediated immunity
|
WO2023092004A1
(en)
|
2021-11-17 |
2023-05-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
US20230183360A1
(en)
|
2021-12-09 |
2023-06-15 |
Janssen Biotech, Inc. |
Use of Amivantamab to Treat Colorectal Cancer
|
WO2023139293A1
(en)
|
2022-01-24 |
2023-07-27 |
Novimmune Sa |
Composition and methods for the selective activation of cytokine signaling pathways
|
WO2023144290A1
(en)
|
2022-01-28 |
2023-08-03 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
WO2023144306A1
(en)
|
2022-01-28 |
2023-08-03 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
TW202342548A
(en)
|
2022-02-07 |
2023-11-01 |
美商威特拉公司 |
Anti-idiotype antibody molecules and uses thereof
|
TW202342057A
(en)
|
2022-02-07 |
2023-11-01 |
美商健生生物科技公司 |
Methods for reducing infusion-related reactions in patients treated with egfr/met bispecific antibodies
|
US20240002544A1
(en)
|
2022-03-07 |
2024-01-04 |
Novimmune Sa |
Cd28 bispecific antibodies for targeted t cell activation
|
WO2023174925A1
(en)
|
2022-03-14 |
2023-09-21 |
Novimmune Sa |
Bispecific gpc3xcd28 and gpc3xcd3 antibodies and their combination for targeted killing of gpc3 positive malignant cells
|
WO2023174521A1
(en)
|
2022-03-15 |
2023-09-21 |
Genmab A/S |
Binding agents binding to epcam and cd137
|
WO2023180346A1
(en)
|
2022-03-22 |
2023-09-28 |
Morphosys Ag |
Deimmunized antibodies specific for cd3
|
TW202346337A
(en)
|
2022-03-29 |
2023-12-01 |
美商恩格姆生物製藥公司 |
Ilt3 and cd3 binding agents and methods of use thereof
|
WO2023198839A2
(en)
|
2022-04-13 |
2023-10-19 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20
|
WO2023209568A1
(en)
|
2022-04-26 |
2023-11-02 |
Novartis Ag |
Multispecific antibodies targeting il-13 and il-18
|
WO2023218046A1
(en)
|
2022-05-12 |
2023-11-16 |
Genmab A/S |
Binding agents capable of binding to cd27 in combination therapy
|
TW202409090A
(en)
|
2022-05-12 |
2024-03-01 |
丹麥商珍美寶股份有限公司 |
Binding agents capable of binding to cd27 in combination therapy
|
WO2023220695A2
(en)
|
2022-05-13 |
2023-11-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
WO2024003837A1
(en)
|
2022-06-30 |
2024-01-04 |
Janssen Biotech, Inc. |
Use of anti-egfr/anti-met antibody to treat gastric or esophageal cancer
|
WO2024030976A2
(en)
|
2022-08-03 |
2024-02-08 |
Voyager Therapeutics, Inc. |
Compositions and methods for crossing the blood brain barrier
|
WO2024052503A1
(en)
|
2022-09-08 |
2024-03-14 |
Institut National de la Santé et de la Recherche Médicale |
Antibodies having specificity to ltbp2 and uses thereof
|
WO2024059739A1
(en)
|
2022-09-15 |
2024-03-21 |
Voyager Therapeutics, Inc. |
Tau binding compounds
|
WO2024079074A1
(en)
|
2022-10-10 |
2024-04-18 |
Universite D'aix Marseille |
ANTI-sCD146 ANTIBODIES AND USES THEREOF
|
WO2024084052A1
(en)
|
2022-10-21 |
2024-04-25 |
Novimmune Sa |
Pd-l1xcd28 bispecific antibodies for immune checkpoint-dependent t cell activation
|
WO2024089551A1
(en)
|
2022-10-25 |
2024-05-02 |
Janssen Biotech, Inc. |
Msln and cd3 binding agents and methods of use thereof
|
WO2024094660A1
(en)
|
2022-10-31 |
2024-05-10 |
Genmab A/S |
Cd38 antibodies and uses thereof
|
WO2024094822A1
(en)
|
2022-11-02 |
2024-05-10 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20 for treating richter's syndrome
|
WO2024095173A1
(en)
|
2022-11-02 |
2024-05-10 |
Janssen Biotech, Inc. |
Methods of treating cancers
|
WO2024115725A1
(en)
|
2022-12-01 |
2024-06-06 |
BioNTech SE |
Multispecific antibody against cd40 and cd137 in combination therapy with anti-pd1 ab and chemotherapy
|