SG11201400405TA - Caninised antibodies and method for the production of same - Google Patents
Caninised antibodies and method for the production of sameInfo
- Publication number
- SG11201400405TA SG11201400405TA SG11201400405TA SG11201400405TA SG11201400405TA SG 11201400405T A SG11201400405T A SG 11201400405TA SG 11201400405T A SG11201400405T A SG 11201400405TA SG 11201400405T A SG11201400405T A SG 11201400405TA SG 11201400405T A SG11201400405T A SG 11201400405TA
- Authority
- SG
- Singapore
- Prior art keywords
- production
- same
- caninised antibodies
- caninised
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/48—Nerve growth factor [NGF]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Computational Biology (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physical Education & Sports Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161531439P | 2011-09-06 | 2011-09-06 | |
| PCT/GB2012/052174 WO2013034900A1 (en) | 2011-09-06 | 2012-09-05 | Caninised antibodies and method for the production of same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201400405TA true SG11201400405TA (en) | 2014-04-28 |
Family
ID=46881091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201400405TA SG11201400405TA (en) | 2011-09-06 | 2012-09-05 | Caninised antibodies and method for the production of same |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20140328838A1 (en) |
| EP (1) | EP2753645B1 (en) |
| JP (5) | JP6010127B2 (en) |
| KR (2) | KR20190094253A (en) |
| CN (1) | CN103906764A (en) |
| AU (1) | AU2012306067B9 (en) |
| CA (2) | CA2835094C (en) |
| ES (1) | ES2665016T3 (en) |
| SG (1) | SG11201400405TA (en) |
| TW (1) | TW201326206A (en) |
| WO (1) | WO2013034900A1 (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2835094C (en) * | 2011-05-06 | 2020-12-22 | David Gearing | Anti-nerve growth factor antibodies and methods of preparing and using the same |
| CN106029697B (en) | 2013-12-20 | 2021-06-04 | 英特维特国际股份有限公司 | Canine antibodies with modified CH2-CH3 sequences |
| CN112851816B (en) | 2014-09-30 | 2024-03-08 | 英特维特国际股份有限公司 | PD-L1 antibodies that bind canine PD-L1 |
| US11091556B2 (en) | 2015-12-18 | 2021-08-17 | Intervet Inc. | Caninized human antibodies to human IL-4R alpha |
| AU2018318440A1 (en) * | 2017-08-15 | 2020-02-13 | Kindred Biosciences, Inc. | IgG Fc variants for veterinary use |
| KR20200130696A (en) * | 2018-03-12 | 2020-11-19 | 조에티스 서비시즈 엘엘씨 | Anti-NGF antibodies and methods thereof |
| EP4114856A4 (en) * | 2020-03-03 | 2023-11-22 | Scout Bio, Inc. | Antigen-binding molecules and uses thereof |
| WO2024051806A1 (en) * | 2022-09-09 | 2024-03-14 | 南京金斯瑞生物科技有限公司 | Method for designing humanized antibody sequence |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| DE68913658T3 (en) | 1988-11-11 | 2005-07-21 | Stratagene, La Jolla | Cloning of immunoglobulin sequences from the variable domains |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| EP0519596B1 (en) * | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | A method for reducing the immunogenicity of antibody variable domains |
| CU22615A1 (en) * | 1994-06-30 | 2000-02-10 | Centro Inmunologia Molecular | PROCEDURE FOR OBTAINING LESS IMMUNOGENIC MONOCLONAL ANTIBODIES. MONOCLONAL ANTIBODIES OBTAINED |
| US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
| US7321026B2 (en) * | 2001-06-27 | 2008-01-22 | Skytech Technology Limited | Framework-patched immunoglobulins |
| US20030190705A1 (en) * | 2001-10-29 | 2003-10-09 | Sunol Molecular Corporation | Method of humanizing immune system molecules |
| EP1485126A4 (en) * | 2001-12-21 | 2007-03-21 | Idexx Lab Inc | Canine immunoglobulin variable domains, caninized antibodies, and methods for making and using them |
| ITRM20030601A1 (en) * | 2003-12-24 | 2005-06-25 | Lay Line Genomics Spa | METHOD FOR THE HUMANIZATION OF HUMANIZED ANTIBODIES AND ANTIBODIES WITH IT OBTAINED. |
| ITRM20040212A1 (en) * | 2004-04-30 | 2004-07-30 | Lay Line Genomics Spa | NON-HUMAN TRANSGENIC ANIMAL AS A MODEL FOR NEURODEGENERATIVE DISEASES AND THEIR EARLY DIAGNOSIS. |
| ITRM20050290A1 (en) * | 2005-06-07 | 2006-12-08 | Lay Line Genomics Spa | USE OF MOLECULES ABLE TO INHIBIT THE BOND BETWEEN NGF AND ITS TRKA RECEPTOR AS AN EXTENDED EFFECT ANALGESICS. |
| EP2725037A1 (en) * | 2008-09-04 | 2014-04-30 | Vet Therapeutics, Inc. | Monoclonal antibodies binding canine CD20 |
| GB2476681B (en) * | 2010-01-04 | 2012-04-04 | Argen X Bv | Humanized camelid VH, VK and VL immunoglobulin domains |
| ES2910305T3 (en) * | 2010-08-19 | 2022-05-12 | Zoetis Belgium S A | Anti-NGF antibodies and their use |
| CA2835094C (en) * | 2011-05-06 | 2020-12-22 | David Gearing | Anti-nerve growth factor antibodies and methods of preparing and using the same |
-
2012
- 2012-05-08 CA CA2835094A patent/CA2835094C/en active Active
- 2012-09-05 US US14/342,943 patent/US20140328838A1/en not_active Abandoned
- 2012-09-05 KR KR1020197022574A patent/KR20190094253A/en not_active Application Discontinuation
- 2012-09-05 ES ES12761785.0T patent/ES2665016T3/en active Active
- 2012-09-05 SG SG11201400405TA patent/SG11201400405TA/en unknown
- 2012-09-05 CA CA2847824A patent/CA2847824A1/en not_active Abandoned
- 2012-09-05 CN CN201280054104.XA patent/CN103906764A/en active Pending
- 2012-09-05 EP EP12761785.0A patent/EP2753645B1/en active Active
- 2012-09-05 WO PCT/GB2012/052174 patent/WO2013034900A1/en unknown
- 2012-09-05 JP JP2014529064A patent/JP6010127B2/en active Active
- 2012-09-05 AU AU2012306067A patent/AU2012306067B9/en active Active
- 2012-09-05 KR KR1020147009219A patent/KR20140062127A/en not_active Application Discontinuation
- 2012-09-06 TW TW101132485A patent/TW201326206A/en unknown
-
2015
- 2015-12-08 JP JP2015239079A patent/JP2016040322A/en active Pending
-
2016
- 2016-06-06 JP JP2016112826A patent/JP2016171812A/en not_active Abandoned
-
2017
- 2017-01-18 JP JP2017006404A patent/JP2017110015A/en active Pending
-
2018
- 2018-12-27 JP JP2018245440A patent/JP2019089772A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20190094253A (en) | 2019-08-12 |
| JP2016040322A (en) | 2016-03-24 |
| NZ622326A (en) | 2015-10-30 |
| JP2016171812A (en) | 2016-09-29 |
| US20140328838A1 (en) | 2014-11-06 |
| AU2012306067A1 (en) | 2014-03-20 |
| TW201326206A (en) | 2013-07-01 |
| JP2019089772A (en) | 2019-06-13 |
| AU2012306067B2 (en) | 2017-01-19 |
| WO2013034900A1 (en) | 2013-03-14 |
| JP6010127B2 (en) | 2016-10-19 |
| KR20140062127A (en) | 2014-05-22 |
| CN103906764A (en) | 2014-07-02 |
| ES2665016T3 (en) | 2018-04-24 |
| JP2017110015A (en) | 2017-06-22 |
| CA2835094C (en) | 2020-12-22 |
| CA2847824A1 (en) | 2013-03-14 |
| EP2753645A1 (en) | 2014-07-16 |
| JP2014527806A (en) | 2014-10-23 |
| EP2753645B1 (en) | 2018-02-21 |
| AU2012306067B9 (en) | 2017-02-23 |
| CA2835094A1 (en) | 2012-11-15 |
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