|
US3536809A
(en)
|
1969-02-17 |
1970-10-27 |
Alza Corp |
Medication method
|
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
|
US3630200A
(en)
|
1969-06-09 |
1971-12-28 |
Alza Corp |
Ocular insert
|
|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US3916899A
(en)
|
1973-04-25 |
1975-11-04 |
Alza Corp |
Osmotic dispensing device with maximum and minimum sizes for the passageway
|
|
US3914250A
(en)
|
1974-08-01 |
1975-10-21 |
American Home Prod |
1,4-Diazepino{8 6,5,4-jk{9 carbazoles
|
|
US4008719A
(en)
|
1976-02-02 |
1977-02-22 |
Alza Corporation |
Osmotic system having laminar arrangement for programming delivery of active agent
|
|
JPS608117B2
(ja)
|
1977-02-08 |
1985-02-28 |
財団法人微生物化学研究会 |
新生理活性物質エステラスチンおよびその製造法
|
|
DE2928485A1
(de)
|
1979-07-14 |
1981-01-29 |
Bayer Ag |
Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
|
|
JPS57151944A
(en)
|
1981-03-16 |
1982-09-20 |
Fuji Photo Film Co Ltd |
Color photosensitive silver halide material
|
|
ZA821577B
(en)
|
1981-04-06 |
1983-03-30 |
Boots Co Plc |
Therapeutic agents
|
|
US4452813A
(en)
|
1981-05-22 |
1984-06-05 |
Taiho Pharmaceutical Company Limited |
Sulfonate derivatives, process for preparing same and antilipemic compositions containing the derivative
|
|
JPS58193541A
(ja)
|
1982-05-07 |
1983-11-11 |
Konishiroku Photo Ind Co Ltd |
熱現像画像記録材料
|
|
JPH0245181B2
(ja)
|
1983-03-16 |
1990-10-08 |
Fuji Photo Film Co Ltd |
Netsugenzokaraakankozairyo
|
|
GB8313320D0
(en)
|
1983-05-14 |
1983-06-22 |
Ciba Geigy Ag |
Coating compositions
|
|
GB8313321D0
(en)
|
1983-05-14 |
1983-06-22 |
Ciba Geigy Ag |
Preparation of mercaptan substituted carboxylic acids
|
|
GB8313322D0
(en)
|
1983-05-14 |
1983-06-22 |
Ciba Geigy Ag |
Heterocyclic-(cyclo)aliphatic carboxylic acids
|
|
CA1247547A
(en)
|
1983-06-22 |
1988-12-28 |
Paul Hadvary |
Leucine derivatives
|
|
GB8412064D0
(en)
|
1984-05-11 |
1984-06-20 |
Ciba Geigy Ag |
Compositions containing heterocyclic corrosion inhibitors
|
|
GB8412065D0
(en)
|
1984-05-11 |
1984-06-20 |
Ciba Geigy Ag |
Preparation of carboxylic acid derivatives
|
|
GB8412063D0
(en)
|
1984-05-11 |
1984-06-20 |
Ciba Geigy Ag |
Compositions containing heterocyclic corrosion inhibitors
|
|
US4851423A
(en)
|
1986-12-10 |
1989-07-25 |
Schering Corporation |
Pharmaceutically active compounds
|
|
IE61928B1
(en)
|
1988-11-29 |
1994-11-30 |
Boots Co Plc |
Treatment of obesity
|
|
US5391571A
(en)
|
1989-11-15 |
1995-02-21 |
American Home Products Corporation |
Cholesterol ester hydrolase inhibitors
|
|
US5112820A
(en)
|
1990-03-05 |
1992-05-12 |
Sterling Drug Inc. |
Anti-glaucoma compositions containing 2- and 3-aminomethyl-6-arylcarbonyl- or 6-phenylthio-2,3-dihydropyrrolo-(1,2,3-de)-1,4-benzoxazines and method of use thereof
|
|
US5081122A
(en)
|
1990-03-05 |
1992-01-14 |
Sterling Drug Inc. |
Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof
|
|
US4973587A
(en)
|
1990-03-08 |
1990-11-27 |
Sterling Drug Inc. |
3-arylcarbonyl-1-aminoalkyl-1H-indole-containing antiglaucoma method
|
|
US5013837A
(en)
|
1990-03-08 |
1991-05-07 |
Sterling Drug Inc. |
3-Arylcarbonyl-1H-indole-containing compounds
|
|
JPH0427854A
(ja)
|
1990-05-23 |
1992-01-30 |
Mitsubishi Heavy Ind Ltd |
レーザ分析装置
|
|
AU658646B2
(en)
|
1991-05-10 |
1995-04-27 |
Rhone-Poulenc Rorer International (Holdings) Inc. |
Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
|
|
PT100905A
(pt)
|
1991-09-30 |
1994-02-28 |
Eisai Co Ltd |
Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
|
|
FR2692575B1
(fr)
|
1992-06-23 |
1995-06-30 |
Sanofi Elf |
Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
US5349056A
(en)
|
1992-10-09 |
1994-09-20 |
Regeneron Pharmaceuticals |
Modified ciliary neurotrophic factors
|
|
US6472178B1
(en)
|
1998-02-27 |
2002-10-29 |
Regeneron Pharmaceuticals, Inc. |
Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
|
|
AU5118893A
(en)
|
1992-10-13 |
1994-05-09 |
Nippon Soda Co., Ltd. |
Oxazole and thiazole derivatives
|
|
US5451677A
(en)
|
1993-02-09 |
1995-09-19 |
Merck & Co., Inc. |
Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
|
|
US5292736A
(en)
|
1993-02-26 |
1994-03-08 |
Sterling Winthrop Inc. |
Morpholinoalkylindenes as antiglaucoma agents
|
|
JPH06298731A
(ja)
|
1993-04-13 |
1994-10-25 |
Fuji Photo Film Co Ltd |
複素環化合物の製造方法
|
|
DE4326151A1
(de)
|
1993-08-04 |
1995-02-09 |
Hoechst Ag |
Aromatische Verbindungen und ihre Verwendung in flüssigkristallinen Mischungen
|
|
CA2134192A1
(en)
|
1993-11-12 |
1995-05-13 |
Michael L. Denney |
5, 6-bicyclic glycoprotein iib/iiia antagonists
|
|
FR2714057B1
(fr)
|
1993-12-17 |
1996-03-08 |
Sanofi Elf |
Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.
|
|
US5705515A
(en)
|
1994-04-26 |
1998-01-06 |
Merck & Co., Inc. |
Substituted sulfonamides as selective β-3 agonists for the treatment of diabetes and obesity
|
|
IL113410A
(en)
|
1994-04-26 |
1999-11-30 |
Merck & Co Inc |
Substituted sulfonamides having an asymmetric center and pharmaceutical compositions containing them
|
|
AU2395095A
(en)
|
1994-04-29 |
1995-11-29 |
G.D. Searle & Co. |
Method of using (h+/k+) atpase inhibitors as antiviral agents
|
|
WO1996000560A2
(en)
|
1994-06-30 |
1996-01-11 |
Minnesota Mining And Manufacturing Company |
Dental impression material with cure-indicating dye
|
|
BR9509610A
(pt)
|
1994-11-07 |
1997-10-28 |
Pfizer |
Ligandos específicos de neuropeptideo Y1
|
|
US5552522A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5552524A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
WO1996023517A1
(en)
|
1995-01-31 |
1996-08-08 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5552523A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5554727A
(en)
|
1995-01-31 |
1996-09-10 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5521283A
(en)
|
1995-01-31 |
1996-05-28 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5559208A
(en)
|
1995-01-31 |
1996-09-24 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
AU4766096A
(en)
|
1995-01-31 |
1996-08-21 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5605886A
(en)
|
1995-01-31 |
1997-02-25 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5532237A
(en)
|
1995-02-15 |
1996-07-02 |
Merck Frosst Canada, Inc. |
Indole derivatives with affinity for the cannabinoid receptor
|
|
US5831115A
(en)
|
1995-04-21 |
1998-11-03 |
Abbott Laboratories |
Inhibitors of squalene synthase and protein farnesyltransferase
|
|
US20020006964A1
(en)
|
1995-05-16 |
2002-01-17 |
Young James W. |
Methods of using and compositions comprising (+) sibutramine optionally in combination with other pharmacologically active compounds
|
|
US5739106A
(en)
|
1995-06-07 |
1998-04-14 |
Rink; Timothy J. |
Appetite regulating compositions
|
|
AU7074496A
(en)
|
1995-09-18 |
1997-04-09 |
Ligand Pharmaceuticals Incorporated |
Ppar gamma antagonists for treating obesity
|
|
FR2741621B1
(fr)
|
1995-11-23 |
1998-02-13 |
Sanofi Sa |
Nouveaux derives de pyrazole, procede pour leur preparation et compositions pharmaceutiques en contenant
|
|
US6482927B1
(en)
|
1995-11-27 |
2002-11-19 |
Millennium Pharmaceuticals, Inc. |
Chimeric proteins comprising the extracellular domain of murine Ob receptor
|
|
AU7626496A
(en)
|
1995-12-01 |
1997-06-27 |
Ciba-Geigy Ag |
Heteroaryl compounds
|
|
AU1328197A
(en)
|
1995-12-01 |
1997-06-19 |
Synaptic Pharmaceutical Corporation |
Aryl sulfonamide and sulfamide derivatives and uses thereof
|
|
AU7692996A
(en)
|
1995-12-01 |
1997-06-27 |
Ciba-Geigy Ag |
Receptor antagonists
|
|
AU7692696A
(en)
|
1995-12-01 |
1997-06-27 |
Novartis Ag |
Heteroaryl derivatives
|
|
AU7692896A
(en)
|
1995-12-01 |
1997-06-27 |
Novartis Ag |
Quinazolin-2,4-diazirines as NPY receptor antagonist
|
|
TW432073B
(en)
|
1995-12-28 |
2001-05-01 |
Pfizer |
Pyrazolopyridine compounds
|
|
CA2244831A1
(en)
|
1996-02-02 |
1997-08-07 |
John T. Olson |
Method of treating diabetes and related disease states
|
|
CA2245524A1
(en)
|
1996-02-02 |
1997-08-07 |
Wei Han |
Antidiabetic agents
|
|
JP2002503202A
(ja)
|
1996-02-02 |
2002-01-29 |
メルク エンド カンパニー インコーポレーテッド |
抗糖尿病薬
|
|
ATE236137T1
(de)
|
1996-02-02 |
2003-04-15 |
Merck & Co Inc |
Heterocyclische verbindungen als antidiabetische mittel und für die behandlung von fettleibigkeit
|
|
WO1997028149A1
(en)
|
1996-02-02 |
1997-08-07 |
Merck & Co., Inc. |
Method for raising hdl cholesterol levels
|
|
AU1618697A
(en)
|
1996-02-06 |
1997-08-28 |
Japan Tobacco Inc. |
Novel compounds and pharmaceutical use thereof
|
|
WO1997046556A1
(en)
|
1996-06-07 |
1997-12-11 |
Merck & Co., Inc. |
OXADIAZOLE BENZENESULFONAMIDES AS SELECTIVE β3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY
|
|
CA2264020A1
(en)
|
1996-08-26 |
1998-03-05 |
Jean Bemis |
Inhibitors of phospholipase enzymes
|
|
IT1288388B1
(it)
|
1996-11-19 |
1998-09-22 |
Angeletti P Ist Richerche Bio |
Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
|
|
CA2274594C
(en)
|
1996-12-16 |
2006-10-10 |
Banyu Pharmaceutical Co., Ltd. |
Aminopyrazole derivatives
|
|
JPH10237049A
(ja)
|
1996-12-24 |
1998-09-08 |
Nippon Chemiphar Co Ltd |
ベンズイソキサゾ−ル誘導体
|
|
JP2001508799A
(ja)
|
1997-01-21 |
2001-07-03 |
スミスクライン・ビーチャム・コーポレイション |
新規カンナビノイド受容体モジュレータ
|
|
EP0968209A1
(en)
|
1997-01-28 |
2000-01-05 |
Merck & Co., Inc. |
THIAZOLE BENZENESULFONAMIDES AS $g(b) 3? AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY
|
|
KR100510794B1
(ko)
|
1997-02-04 |
2005-08-31 |
더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 |
살진균 카르복스아미드
|
|
HU228509B1
(en)
|
1997-02-21 |
2013-03-28 |
Bayer Ip Gmbh |
Aryl sulfonamides and analogues thereof and their use in the treatment of neurodegenerative diseases
|
|
DE69819311T2
(de)
|
1997-03-07 |
2004-07-29 |
Metabasis Therapeutics Inc., San Diego |
Neue benzimidazol inhibitoren der fructose-1,6-bisphosphatase
|
|
US6284748B1
(en)
|
1997-03-07 |
2001-09-04 |
Metabasis Therapeutics, Inc. |
Purine inhibitors of fructose 1,6-bisphosphatase
|
|
AU6691798A
(en)
|
1997-03-07 |
1998-09-22 |
Metabasis Therapeutics, Inc. |
Novel indole and azaindole inhibitors of fructose-1,6-bisphosphatase
|
|
CA2283797A1
(en)
|
1997-03-18 |
1998-09-24 |
Paul Elliot Bender |
Novel cannabinoid receptor agonists
|
|
FR2761265B1
(fr)
|
1997-03-28 |
1999-07-02 |
Sanofi Sa |
Composition pharmaceutique pour l'administration orale d'un derive du n-piperidino-3-pyrazolecarboxamide, de ses sels et de leurs solvates
|
|
FR2761266B1
(fr)
|
1997-03-28 |
1999-07-02 |
Sanofi Sa |
Composition pharmaceutique formee par granulation humide pour l'administration orale d'un derive du n-piperidino-3- pyrazolecarboxamide, de ses sels et de leurs solvates
|
|
WO1998047505A1
(en)
|
1997-04-23 |
1998-10-29 |
Banyu Pharmaceutical Co., Ltd. |
Neuropeptide y receptor antagonist
|
|
US6001836A
(en)
|
1997-05-28 |
1999-12-14 |
Bristol-Myers Squibb Company |
Dihydropyridine NPY antagonists: cyanoguanidine derivatives
|
|
ID24054A
(id)
|
1997-06-10 |
2000-07-06 |
Glaxo Group Ltd Glaxo |
Turunan turunan benzimidazol
|
|
SE9702457D0
(sv)
|
1997-06-26 |
1997-06-26 |
Pharmacia & Upjohn Ab |
Screening
|
|
CN1268137A
(zh)
|
1997-07-03 |
2000-09-27 |
杜邦药品公司 |
治疗神经失调的咪唑并嘧啶和咪唑并吡啶
|
|
AU8127998A
(en)
|
1997-07-11 |
1999-02-08 |
Japan Tobacco Inc. |
Quinoline compounds and medicinal uses thereof
|
|
US6440961B1
(en)
|
1997-10-27 |
2002-08-27 |
Dr. Reddy's Research Foundation |
Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
|
|
CN1280574A
(zh)
|
1997-10-27 |
2001-01-17 |
雷迪研究基金会 |
新的杂环化合物及其在医药中的应用、它们的制备方法和含有它们的药物组合物
|
|
WO1999019313A1
(en)
|
1997-10-27 |
1999-04-22 |
Dr. Reddy's Research Foundation |
Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
|
|
AU1887999A
(en)
|
1998-01-29 |
1999-08-16 |
Dr. Reddy's Research Foundation |
Novel alkanoic acids and their use in medicine, process for their preparation and pharmaceutical compositions containing them
|
|
KR20010041346A
(ko)
|
1998-02-25 |
2001-05-15 |
브루스 엠. 에이센, 토마스 제이 데스로저 |
포스포리파제 ａ2 억제제
|
|
US6312662B1
(en)
|
1998-03-06 |
2001-11-06 |
Metabasis Therapeutics, Inc. |
Prodrugs phosphorus-containing compounds
|
|
JP4741725B2
(ja)
|
1998-03-06 |
2011-08-10 |
メタベイシス・セラピューティクス・インコーポレーテッド |
リン含有化合物のための新規なプロドラッグ
|
|
EP1068207A1
(en)
|
1998-04-02 |
2001-01-17 |
Neurogen Corporation |
AMINOALKYL SUBSTITUTED 9H-PYRIDINO 2,3-b]INDOLE AND 9H-PYRIMIDINO 4,5-b]INDOLE DERIVATIVES
|
|
DK1076644T3
(da)
|
1998-04-29 |
2004-08-30 |
Ortho Mcneil Pharm Inc |
N-Substituerede aminotetraliner som ligander for neutopeptid Y Y5-receptoren, der er nyttig til behandling af fedme og andre lidelser
|
|
NZ504106A
(en)
|
1998-05-27 |
2003-02-28 |
Dr |
Fused Oxazine, Thiazine and pipyridine compounds, process for their preparation and pharmaceutical compositions containing them
|
|
US6329395B1
(en)
|
1998-06-08 |
2001-12-11 |
Schering Corporation |
Neuropeptide Y5 receptor antagonists
|
|
EP1085869A4
(en)
|
1998-06-11 |
2001-10-04 |
Merck & Co Inc |
Spiropiperidine derivatives as melanocortin receptor agonists
|
|
PL203730B1
(pl)
|
1998-07-15 |
2009-11-30 |
Teijin Ltd |
Pochodna tiobenzimidazolu, kompozycja farmaceutyczna i jej zastosowanie
|
|
HN1998000027A
(es)
|
1998-08-19 |
1999-06-02 |
Bayer Ip Gmbh |
Arilsulfonamidas y analagos
|
|
DE19837627A1
(de)
|
1998-08-19 |
2000-02-24 |
Bayer Ag |
Neue Aminosäureester von Arylsulfonamiden und Analoga
|
|
US6358951B1
(en)
|
1998-08-21 |
2002-03-19 |
Pfizer Inc. |
Growth hormone secretagogues
|
|
DE69910045T2
(de)
|
1998-09-09 |
2004-04-22 |
Metabasis Therapeutics Inc., San Diego |
Neue heteroaromatische fructose 1,6-bisphosphatase inhibitoren
|
|
JP2002525067A
(ja)
|
1998-09-10 |
2002-08-13 |
ミレニアム ファーマシューティカルズ インク． |
レプチン誘導遺伝子
|
|
US6337332B1
(en)
|
1998-09-17 |
2002-01-08 |
Pfizer Inc. |
Neuropeptide Y receptor antagonists
|
|
DE19844547C2
(de)
|
1998-09-29 |
2002-11-07 |
Aventis Pharma Gmbh |
Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
US7417038B1
(en)
|
1998-10-15 |
2008-08-26 |
Imperial Innovations Limited |
Methods of treating cachexia
|
|
EP1123269A1
(en)
|
1998-10-21 |
2001-08-16 |
Novo Nordisk A/S |
New compounds, their preparation and use
|
|
WO2000023415A1
(en)
|
1998-10-21 |
2000-04-27 |
Novo Nordisk A/S |
New compounds, their preparation and use
|
|
AU6325599A
(en)
|
1998-10-21 |
2000-05-08 |
Dr. Reddy's Research Foundation |
New compounds, their preparation and use
|
|
ATE314371T1
(de)
|
1998-11-10 |
2006-01-15 |
Merck & Co Inc |
Spiro-indole als y5-rezeptor antagonisten
|
|
ES2161594B1
(es)
|
1998-12-17 |
2003-04-01 |
Servier Lab |
Nuevos derivados de la hidrazida, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
|
|
US6344481B1
(en)
|
1999-03-01 |
2002-02-05 |
Pfizer Inc. |
Thyromimetic antiobesity agents
|
|
HK1043796B
(en)
|
1999-03-05 |
2007-02-23 |
Metabasis Therapeutics, Inc. |
Novel phosphorus-containing prodrugs
|
|
CA2367666C
(en)
|
1999-03-19 |
2008-11-25 |
Carl M. Mendel |
Method of treating eating disorders
|
|
FR2792314B1
(fr)
|
1999-04-15 |
2001-06-01 |
Adir |
Nouveaux composes aminotriazoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
US6340683B1
(en)
|
1999-04-22 |
2002-01-22 |
Synaptic Pharmaceutical Corporation |
Selective NPY (Y5) antagonists (triazines)
|
|
PT1183245E
(pt)
|
1999-04-22 |
2007-07-12 |
Lundbeck & Co As H |
Antagonistas selectivos de npy (y5)
|
|
AU4659200A
(en)
|
1999-05-05 |
2000-11-21 |
Ortho-Mcneil Pharmaceutical, Inc. |
3a,4,5,9b-tetrahydro-1h-benz(e)indol-2-yl amine-derived neuropeptide Y receptors ligands useful in the treatment of obesity and other disorders
|
|
AU778393B2
(en)
|
1999-05-12 |
2004-12-02 |
Ortho-Mcneil Pharmaceutical, Inc. |
Pyrazole carboxamides useful for the treatment of obesity and other disorders
|
|
CA2377369A1
(en)
|
1999-06-04 |
2000-12-14 |
Merck & Co., Inc. |
Substituted piperidines as melanocortin-4 receptor agonists
|
|
DE60023141T2
(de)
|
1999-06-30 |
2006-06-14 |
Lundbeck As Valby H |
Selektive npy (y5) antagonisten
|
|
CN1171872C
(zh)
|
1999-06-30 |
2004-10-20 |
图拉列克股份有限公司 |
调节PPARγ活性的化合物
|
|
AU6000900A
(en)
|
1999-07-23 |
2001-02-13 |
Astrazeneca Uk Limited |
Carbazole derivatives and their use as neuropeptide y5 receptor ligands
|
|
MXPA02000927A
(es)
|
1999-07-28 |
2003-07-14 |
Johnson & Johnson |
Amina y derivados de amida como ligandos para el receptor del neuropeptido y y5 utiles en el tratamiento de obesidad y otros trastornos.
|
|
CA2381008A1
(en)
|
1999-08-04 |
2001-02-15 |
Millennium Pharmaceuticals, Inc. |
Melanocortin-4 receptor binding compounds and methods of use thereof
|
|
TWI279402B
(en)
|
1999-08-20 |
2007-04-21 |
Banyu Pharma Co Ltd |
Spiro compounds having NPY antagonistic activities and agents containing the same
|
|
AU7315800A
(en)
|
1999-09-20 |
2001-04-24 |
Takeda Chemical Industries Ltd. |
Mch antagonists
|
|
EP1218381B1
(en)
|
1999-09-30 |
2006-12-06 |
Neurogen Corporation |
AMINO SUBSTITUTED PYRAZOLO¬1,5-a|-1,5-PYRIMIDINES AND PYRAZOLO¬1,5-a|-1,3,5-TRIAZINES
|
|
JP2003510325A
(ja)
|
1999-09-30 |
2003-03-18 |
ニューロジェン・コーポレーション |
ある種のアルキレンジアミン−置換ピラゾロ［１，５−ａ］−１，５−ピリミジン及びピラゾロ［１，５−ａ］−１，３，５−トリアジン
|
|
ES2258476T3
(es)
|
1999-09-30 |
2006-09-01 |
Neurogen Corporation |
Ciertos heterociclos sustituidos con alquilendiaminas.
|
|
TWI262185B
(en)
|
1999-10-01 |
2006-09-21 |
Eisai Co Ltd |
Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives
|
|
AU7802700A
(en)
|
1999-10-06 |
2001-05-10 |
Melacure Therapeutics Ab |
Guanidine derivatives and their use in the production of a medicament for blocking xanthine oxidase/dehydrogenase
|
|
ES2225231T3
(es)
|
1999-10-06 |
2005-03-16 |
Boehringer Ingelheim Pharmaceuticals Inc. |
Compuestos heterociclicos, utiles como inhibidores de tirosina quinasas.
|
|
WO2001027068A1
(en)
|
1999-10-13 |
2001-04-19 |
Pfizer Products Inc. |
Biaryl ether derivatives useful as monoamine reuptake inhibitors
|
|
DE19949319A1
(de)
|
1999-10-13 |
2001-06-13 |
Ruetgers Vft Ag |
Verfahren zur Herstellung von Arylalkylethern
|
|
CA2389703A1
(en)
|
1999-11-05 |
2001-05-10 |
Aventis Pharma Deutschland Gmbh |
Indeno-, naphtho-, and benzocyclohepta-dihydrothiazole derivatives, the production thereof and their use as anorectic medicaments
|
|
AR032292A1
(es)
|
1999-12-16 |
2003-11-05 |
Schering Corp |
Imidazoles sustituidos, composiciones farmaceuticas y el uso de dichos imidazoles para la manufactura de un medicamento para los tratamientos de desordenes en la alimentacion
|
|
NZ520028A
(en)
|
2000-01-17 |
2004-07-30 |
Teijin Ltd |
Benzimidazole derivatives
|
|
CA2365118A1
(en)
|
2000-01-17 |
2001-07-26 |
Teijin Limited |
Inhibitor against human chymase activity
|
|
AU2001229491A1
(en)
|
2000-01-18 |
2001-07-31 |
Merck And Co., Inc. |
Cyclic peptides as potent and selective melanocortin-4 receptor antagonists
|
|
AU2001228325A1
(en)
|
2000-02-01 |
2001-08-14 |
Novo-Nordisk A/S |
Use of compounds for the regulation of food intake
|
|
US6653304B2
(en)
|
2000-02-11 |
2003-11-25 |
Bristol-Myers Squibb Co. |
Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases
|
|
JP2001226269A
(ja)
|
2000-02-18 |
2001-08-21 |
Takeda Chem Ind Ltd |
メラニン凝集ホルモン拮抗剤
|
|
GB0004003D0
(en)
|
2000-02-22 |
2000-04-12 |
Knoll Ag |
Therapeutic agents
|
|
AU2001234128B2
(en)
|
2000-02-22 |
2004-11-11 |
Banyu Pharmaceutical Co., Ltd. |
Novel imidazoline compounds
|
|
NZ520926A
(en)
|
2000-02-23 |
2004-08-27 |
Aventis Pharma Gmbh |
8,8a-dihydro-indeno[1,2-d]thiazole derivatives, substituted in position 8a, a method for their production and their use as medicaments, e.g. anorectic agents
|
|
US6531478B2
(en)
|
2000-02-24 |
2003-03-11 |
Cheryl P. Kordik |
Amino pyrazole derivatives useful for the treatment of obesity and other disorders
|
|
SK285571B6
(sk)
|
2000-02-26 |
2007-04-05 |
Sanofi-Aventis Deutschland Gmbh |
8,8a-Dihydroindeno[1,2-d]tiazolové deriváty nesúce v polohe 2 substituent so sulfónamidovou štruktúrou, spôsob ich prípravy a farmaceutické prostriedky, ktoré ich obsahujú
|
|
FR2805810B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Compositions pharmaceutiques contenant des derives de 3- amino-azetidine, les nouveaux derives et leur preparation
|
|
FR2805818B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
|
|
FR2805817B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation
|
|
EP1132389A1
(en)
|
2000-03-06 |
2001-09-12 |
Vernalis Research Limited |
New aza-indolyl derivatives for the treatment of obesity
|
|
AU2001260113B2
(en)
|
2000-03-14 |
2006-04-06 |
Actelion Pharmaceuticals Ltd. |
1,2,3,4-tetrahydroisoquinoline derivatives
|
|
UA74367C2
(uk)
|
2000-03-23 |
2005-12-15 |
Сольве Фармас'Ютікалз Б.В. |
ПОХІДНІ 4,5-ДИГІДРО-1Н-ПІРАЗОЛУ, ЩО ВИЯВЛЯЮТЬ АНТАГОНІСТИЧНУ АКТИВНІСТЬ ЩОДО СВ<sub>1</sub>, СПОСІБ ЇХ ОДЕРЖАННЯ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ТА СПОСІБ ЇЇ ВИГОТОВЛЕННЯ, СПОСІБ ЛІКУВАННЯ ЗАХВОРЮВАНЬ (ВАРІАНТИ)
|
|
JP2003528088A
(ja)
|
2000-03-23 |
2003-09-24 |
メルク エンド カムパニー インコーポレーテッド |
メラノコルチン受容体作働薬としての置換ピペリジン類
|
|
CA2403631A1
(en)
|
2000-03-23 |
2001-09-27 |
Brenda L. Palucki |
Spiropiperidine derivatives as melanocortin receptor agonists
|
|
US6600015B2
(en)
|
2000-04-04 |
2003-07-29 |
Hoffmann-La Roche Inc. |
Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity
|
|
EP1142886A1
(en)
|
2000-04-07 |
2001-10-10 |
Aventis Pharma Deutschland GmbH |
Percyquinnin, a process for its production and its use as a pharmaceutical
|
|
JP2001354671A
(ja)
|
2000-04-14 |
2001-12-25 |
Nippon Chemiphar Co Ltd |
ペルオキシソーム増殖剤応答性受容体δの活性化剤
|
|
AU2001248279A1
(en)
|
2000-04-17 |
2001-10-30 |
Novo-Nordisk A/S |
New compounds, their preparation and use
|
|
CA2407149C
(en)
|
2000-04-28 |
2010-10-12 |
Takeda Chemical Industries, Ltd. |
Melanin-concentrating hormone antagonist
|
|
GB0010757D0
(en)
|
2000-05-05 |
2000-06-28 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0011013D0
(en)
|
2000-05-09 |
2000-06-28 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2001085173A1
(en)
|
2000-05-10 |
2001-11-15 |
Bristol-Myers Squibb Company |
Alkylamine derivatives of dihydropyridine npy antagonists
|
|
US6444675B2
(en)
|
2000-05-10 |
2002-09-03 |
Bristol-Myers Squibb Company |
4-alkyl and 4-cycloalkyl derivatives of dihydropyridine NPY antagonists
|
|
US6432960B2
(en)
|
2000-05-10 |
2002-08-13 |
Bristol-Myers Squibb Company |
Squarate derivatives of dihydropyridine NPY antagonists
|
|
CA2408486A1
(en)
|
2000-05-11 |
2001-11-15 |
Bristol-Myers Squibb Company |
Tetrahydroisoquinoline analogs useful as growth hormone secretagogues
|
|
JP2002371059A
(ja)
|
2000-05-16 |
2002-12-26 |
Takeda Chem Ind Ltd |
メラニン凝集ホルモン拮抗剤
|
|
CA2408913A1
(en)
|
2000-05-16 |
2001-11-22 |
Takeda Chemical Industries, Ltd. |
Melanin-concentrating hormone antagonist
|
|
AU2001259056A1
(en)
|
2000-05-17 |
2001-11-26 |
Eli Lilly And Company |
Method for selectively inhibiting ghrelin action
|
|
US6391881B2
(en)
|
2000-05-19 |
2002-05-21 |
Bristol-Myers Squibb Company |
Thiourea derivatives of dihydropyridine NPY antagonists
|
|
SE0001899D0
(sv)
|
2000-05-22 |
2000-05-22 |
Pharmacia & Upjohn Ab |
New compounds
|
|
CA2410597A1
(en)
|
2000-05-30 |
2001-12-06 |
Merck & Co., Inc. |
Melanocortin receptor agonists
|
|
US6645987B2
(en)
|
2000-06-15 |
2003-11-11 |
Schering Corporation |
Nor-seco himbacine derivatives useful as thrombin receptor antagonists
|
|
ES2238458T3
(es)
|
2000-06-16 |
2005-09-01 |
Smithkline Beecham Plc |
Piperidinas para uso como antagonistas de los receptores de orexina.
|
|
EP1299362A4
(en)
|
2000-07-05 |
2004-11-03 |
Synaptic Pharma Corp |
SELECTIVE RECEPTOR ANTAGONISTS OF MELANINE CONCENTRATING HORMON-1 (MCH1) AND THEIR USE
|
|
MXPA03000174A
(es)
|
2000-07-06 |
2003-09-22 |
Neurogen Corp |
Ligandos de receptor de hormona concentradora de melanina.
|
|
GB0019357D0
(en)
|
2000-08-07 |
2000-09-27 |
Melacure Therapeutics Ab |
Novel phenyl guanidines
|
|
CN1443198A
(zh)
|
2000-07-24 |
2003-09-17 |
阿达纳生物科学有限公司 |
Ghrelin拮抗剂
|
|
CN1277828C
(zh)
|
2000-07-31 |
2006-10-04 |
霍夫曼-拉罗奇有限公司 |
哌嗪衍生物
|
|
US6768024B1
(en)
|
2000-08-04 |
2004-07-27 |
Lion Bioscience Ag |
Triamine derivative melanocortin receptor ligands and methods of using same
|
|
GB0019359D0
(en)
|
2000-08-07 |
2000-09-27 |
Melacure Therapeutics Ab |
Novel guanidines
|
|
DE60140708D1
(de)
|
2000-08-10 |
2010-01-14 |
Mitsubishi Tanabe Pharma Corp |
Prolinderivative und deren Verwendung als Medikamente
|
|
EP1310494B1
(en)
|
2000-08-11 |
2012-01-25 |
Nippon Chemiphar Co., Ltd. |
PPAR (delta) ACTIVATORS
|
|
EP1313470A4
(en)
|
2000-08-17 |
2005-02-16 |
Gliatech Inc |
NEW ALICYCLIC IMIDAZOLE AS H 3 ACTIVE SUBSTANCES
|
|
AU2001288294A1
(en)
|
2000-08-21 |
2002-03-04 |
Merck And Co., Inc. |
Anti-hypercholesterolemic drug combination
|
|
WO2002015905A1
(en)
|
2000-08-21 |
2002-02-28 |
Gliatech, Inc. |
The use of histamine h3 receptor inverse agonists for the control of appetite and treatment of obesity
|
|
EP1320366A4
(en)
|
2000-08-23 |
2005-04-06 |
Merck & Co Inc |
SUBSTITUTED PIPERIDINES AS MELANOCORTIN RECEPTOR AGONISTS
|
|
US20020037829A1
(en)
|
2000-08-23 |
2002-03-28 |
Aronson Peter S. |
Use of DPPIV inhibitors as diuretic and anti-hypertensive agents
|
|
US6900226B2
(en)
|
2000-09-06 |
2005-05-31 |
Hoffman-La Roche Inc. |
Neuropeptide Y antagonists
|
|
JP2004509108A
(ja)
|
2000-09-14 |
2004-03-25 |
シェーリング コーポレイション |
置換尿素神経ペプチドｙｙ５受容体アンタゴニスト
|
|
AU2001292480A1
(en)
|
2000-09-26 |
2002-04-08 |
Biovitrum Ab |
Novel pyridazine compounds for the treatment of diabetes
|
|
AU2001292518A1
(en)
|
2000-09-26 |
2002-04-08 |
Biovitrum Ab |
Novel compounds
|
|
BR0114630A
(pt)
|
2000-10-13 |
2003-07-01 |
Lilly Co Eli |
Secretagogos de hormÈnio do crescimento
|
|
WO2002044152A1
(en)
|
2000-10-16 |
2002-06-06 |
F. Hoffmann-La Roche Ag |
Indoline derivatives and their use as 5-ht2 receptor ligands
|
|
CN1469876A
(zh)
|
2000-10-20 |
2004-01-21 |
�Ʒ� |
α-芳基乙醇胺及其用作β-3肾上腺素能受体激动剂的用途
|
|
JP4734705B2
(ja)
|
2000-10-31 |
2011-07-27 |
三菱化学株式会社 |
リチウム二次電池用正極材料、リチウム二次電池用正極及びリチウム二次電池
|
|
AU2002227170A1
(en)
|
2000-11-03 |
2002-05-15 |
Wyeth |
Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives
|
|
IL154928A0
(en)
|
2000-11-10 |
2003-10-31 |
Lilly Co Eli |
3-substituted oxindole beta 3 agonists
|
|
WO2002040019A1
(en)
|
2000-11-15 |
2002-05-23 |
Banyu Pharmaceutical Co.,Ltd. |
Benzimidazole derivatives
|
|
IL155702A0
(en)
|
2000-11-20 |
2003-11-23 |
Biovitrum Ab |
Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5-ht2 receptor
|
|
EP1337518B1
(en)
|
2000-11-20 |
2009-06-17 |
Biovitrum AB (publ) |
Piperazinylpyrazines compounds as antagonists of serotonin 5-ht2 receptor
|
|
AU2002224885A1
(en)
|
2000-11-28 |
2002-06-11 |
Smithkline Beecham Plc |
Morpholine derivatives as antagonists of orexin receptors
|
|
WO2002046154A1
(fr)
|
2000-12-05 |
2002-06-13 |
Nippon Chemiphar Co., Ltd. |
Activateurs $g(d) de recepteur active par un proliferateur du peroxysome
|
|
AU2002224139A1
(en)
|
2000-12-05 |
2002-06-18 |
Nippon Chemiphar Co. Ltd. |
Ppar (peroxisome proliferator activated receptor) activators
|
|
US6566367B2
(en)
|
2000-12-12 |
2003-05-20 |
Pfizer Inc. |
Spiro[isobenzofuran-1,4′-piperidin]-3-ones and 3H-spiroisobenzofuran-1,4′-piperidines
|
|
GB0030710D0
(en)
|
2000-12-15 |
2001-01-31 |
Hoffmann La Roche |
Piperazine derivatives
|
|
ES2316486T3
(es)
|
2000-12-21 |
2009-04-16 |
Schering Corporation |
Antagonsitas de los receptores y5 del neuropeptido y heteroaril-urea.
|
|
JP2004520324A
(ja)
|
2000-12-22 |
2004-07-08 |
アストラゼネカ アクチボラグ |
カルバゾール誘導体およびニューロペプチドｙ５受容体リガンドとしてのそれらの使用
|
|
US6472394B1
(en)
|
2000-12-22 |
2002-10-29 |
Schering Corporation |
MCH antagonists and their use in the treatment of obesity
|
|
CN1250549C
(zh)
|
2000-12-27 |
2006-04-12 |
霍夫曼-拉罗奇有限公司 |
吲哚衍生物及其作为5－ht2b和5－ht2c受体配体的应用
|
|
WO2002051232A2
(en)
|
2000-12-27 |
2002-07-04 |
Actelion Pharmaceuticals Ltd. |
Novel benzazepines and related heterocyclic derivatives
|
|
EP1368339A1
(en)
|
2001-01-23 |
2003-12-10 |
Eli Lilly & Company |
Substituted piperidines/piperazines as melanocortin receptor agonists
|
|
CA2432985A1
(en)
|
2001-01-23 |
2002-08-01 |
Vincent Mancuso |
Piperazine- and piperidine-derivatives as melanocortin receptor agonists
|
|
JP2004524297A
(ja)
|
2001-01-23 |
2004-08-12 |
イーライ・リリー・アンド・カンパニー |
メラノコルチン受容体アゴニスト
|
|
KR20030074774A
(ko)
|
2001-02-02 |
2003-09-19 |
다케다 야쿠힌 고교 가부시키가이샤 |
접합 헤테로시클릭 화합물
|
|
CA2436741A1
(en)
|
2001-02-05 |
2002-08-15 |
Dr. Reddy's Laboratories Limited |
Aryl substituted alkylcarboxylic acids as hypocholesterolemic agents
|
|
EP1363890A4
(en)
|
2001-02-07 |
2009-06-10 |
Ore Pharmaceuticals Inc |
MELANOCORTIN-4-RECEPTOR BINDING COMPOUNDS AND METHOD FOR THEIR APPLICATION
|
|
US20020119958A1
(en)
|
2001-02-13 |
2002-08-29 |
Shinichiro Tojo |
Therapeutic agent for hyperlipidemia
|
|
CA2437035C
(en)
|
2001-02-24 |
2009-01-06 |
International Business Machines Corporation |
Global interrupt and barrier networks
|
|
DE60215132T2
(de)
|
2001-02-28 |
2007-08-23 |
Merck & Co., Inc. |
Acylierte piperidin-derivate als melanocortin-4-rezeptor-agonisten
|
|
JP4104983B2
(ja)
|
2001-02-28 |
2008-06-18 |
メルク エンド カムパニー インコーポレーテッド |
メラノコルチン−４受容体作動薬としてのアシル化ピペリジン誘導体
|
|
AU2002250343B2
(en)
|
2001-02-28 |
2006-05-25 |
Merck Sharp & Dohme Corp. |
Acylated piperidine derivatives as melanocortin-4 receptor agonists
|
|
GB0105772D0
(en)
|
2001-03-08 |
2001-04-25 |
Sterix Ltd |
Use
|
|
EP1370520A1
(en)
|
2001-03-21 |
2003-12-17 |
Pharmacopeia, Inc. |
Aryl and biaryl compounds having mch modulatory activity
|
|
US6900329B2
(en)
|
2001-03-21 |
2005-05-31 |
Schering Corporation |
MCH antagonists and their use in the treatment of obesity
|
|
ATE284872T1
(de)
|
2001-03-22 |
2005-01-15 |
Solvay Pharm Bv |
4,5-dihydro-1h-pyrazolderivate mit cb1- antagonistischer wirkung
|
|
WO2002076957A1
(en)
|
2001-03-23 |
2002-10-03 |
Nippon Chemiphar Co.,Ltd. |
Activator for peroxisome proliferator-activated receptor
|
|
US20050038022A1
(en)
|
2001-03-26 |
2005-02-17 |
Unisearch Limited |
Method for treatment of cancer and compositions for use therein
|
|
US7253178B2
(en)
|
2001-03-28 |
2007-08-07 |
Eisai Co., Ltd. |
Carboxylic acids
|
|
WO2001074782A1
(en)
|
2001-03-29 |
2001-10-11 |
Molecular Design International, Inc. |
β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
|
|
US7244861B2
(en)
|
2001-03-30 |
2007-07-17 |
Eisai Co., Ltd. |
Benzene compound and salt thereof
|
|
GB0108631D0
(en)
|
2001-04-05 |
2001-05-30 |
Melacure Therapeutics Ab |
Novel benzylideneamino guanidines and their uses as ligands to the melanocortin receptors
|
|
JP4280073B2
(ja)
|
2001-04-12 |
2009-06-17 |
ファーマコペイア ドラッグ ディスカバリー， インコーポレイテッド |
Ｍｃｈアンタゴニストとして使用されるアリールピペリジンおよびビアリールピペリジン
|
|
US6573287B2
(en)
|
2001-04-12 |
2003-06-03 |
Bristo-Myers Squibb Company |
2,1-oxazoline and 1,2-pyrazoline-based inhibitors of dipeptidyl peptidase IV and method
|
|
MXPA03010129A
(es)
|
2001-05-05 |
2004-03-10 |
Smithkline Beecham Plc |
N-aroilaminas-ciclicas.
|
|
EP1435955A2
(en)
|
2001-05-05 |
2004-07-14 |
SmithKline Beecham P.L.C. |
N-aroyl cyclic amine derivatives as orexin receptor antagonists
|
|
US7030150B2
(en)
|
2001-05-11 |
2006-04-18 |
Trimeris, Inc. |
Benzimidazole compounds and antiviral uses thereof
|
|
FR2824825B1
(fr)
|
2001-05-15 |
2005-05-06 |
Servier Lab |
Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
AU2002338896B2
(en)
|
2001-05-21 |
2006-04-27 |
F.Hoffman-La Roche Ag |
Quinoline derivatives as ligands for the neuropeptide Y receptor
|
|
JP2005515961A
(ja)
|
2001-05-22 |
2005-06-02 |
ニューロジェン コーポレイション |
メラニン凝集ホルモン受容体リガンド：置換１−ベンジル−４−アリールピペラジン類似体
|
|
US6548538B2
(en)
|
2001-05-22 |
2003-04-15 |
Bayer Aktiengesellschaft |
Propionic acid derivatives
|
|
US7199147B2
(en)
|
2001-06-12 |
2007-04-03 |
Dainippon Sumitomo Pharma Co., Ltd. |
Rho kinase inhibitors
|
|
JP2004535433A
(ja)
|
2001-06-20 |
2004-11-25 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病治療用のジペプチジルペプチダーゼ阻害薬
|
|
WO2003000685A1
(fr)
|
2001-06-20 |
2003-01-03 |
Takeda Chemical Industries, Ltd. |
Derives heterocycliques a 5 chainons
|
|
CA2450475A1
(en)
|
2001-06-20 |
2003-01-03 |
Linda Brockunier |
Dipeptidyl peptidase inhibitors for the treatment of diabetes
|
|
US6825198B2
(en)
|
2001-06-21 |
2004-11-30 |
Pfizer Inc |
5-HT receptor ligands and uses thereof
|
|
GB0115517D0
(en)
|
2001-06-25 |
2001-08-15 |
Ferring Bv |
Novel antidiabetic agents
|
|
SE0102299D0
(sv)
|
2001-06-26 |
2001-06-26 |
Astrazeneca Ab |
Compounds
|
|
US7223791B2
(en)
|
2001-06-26 |
2007-05-29 |
Takeda Pharmaceutical Company Limited |
Function regulator for retinoid relative receptor
|
|
ES2296962T3
(es)
|
2001-06-27 |
2008-05-01 |
Smithkline Beecham Corporation |
Pirrolidinas como inhibidores de dipeptidil peptidasa.
|
|
DE10150203A1
(de)
|
2001-10-12 |
2003-04-17 |
Probiodrug Ag |
Peptidylketone als Inhibitoren der DPIV
|
|
CN1990469A
(zh)
|
2001-06-27 |
2007-07-04 |
史密丝克莱恩比彻姆公司 |
作为二肽酶抑制剂的氟代吡咯烷
|
|
CN1688599A
(zh)
|
2001-06-27 |
2005-10-26 |
前体生物药物股份有限公司 |
二肽基肽酶iv抑制剂的新用途
|
|
DE60221983T2
(de)
|
2001-06-27 |
2008-05-15 |
Smithkline Beecham Corp. |
Fluorpyrrolidine als dipeptidyl-peptidase inhibitoren
|
|
EP1404682B1
(en)
|
2001-06-29 |
2005-09-14 |
Novo Nordisk A/S |
Method of inhibiting ptp 1b and/or t-cell ptp and/or other ptpases with an asp residue at position 48
|
|
US6688713B2
(en)
|
2001-07-02 |
2004-02-10 |
Mitsubishi Digital Electronics America, Inc. |
Television base casting
|
|
EP1404675B1
(en)
|
2001-07-03 |
2008-03-12 |
Novo Nordisk A/S |
Dpp-iv-inhibiting purine derivatives for the treatment of diabetes
|
|
JP3532537B2
(ja)
|
2001-07-05 |
2004-05-31 |
株式会社テムコジャパン |
骨伝導ヘッドセット
|
|
JP2004536104A
(ja)
|
2001-07-05 |
2004-12-02 |
シナプティック・ファーマスーティカル・コーポレーション |
Ｍｃｈ選択的アンタゴニストとしての置換されたアニリン−ピペリジン誘導体
|
|
UA74912C2
(en)
|
2001-07-06 |
2006-02-15 |
Merck & Co Inc |
Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
|
|
ITMI20011483A1
(it)
|
2001-07-11 |
2003-01-11 |
Res & Innovation Soc Coop A R |
Uso di composti come antagonisti funzionali ai recettori centrali deicannabinoidi
|
|
EP1409521A2
(en)
|
2001-07-12 |
2004-04-21 |
Merck & Co., Inc. |
Cyclic peptides as potent and selective melanocortin-4 receptor agonists
|
|
WO2003007990A1
(en)
|
2001-07-18 |
2003-01-30 |
Sumitomo Pharmaceuticals Company, Limited |
Myosin agonist
|
|
ATE411021T1
(de)
|
2001-07-18 |
2008-10-15 |
Merck & Co Inc |
Überbrückte piperidinderivate als melanocortin- rezeptor-agonisten
|
|
WO2003007887A2
(en)
|
2001-07-20 |
2003-01-30 |
Merck & Co., Inc. |
Substituted imidazoles as cannabinoid receptor modulators
|
|
US6977264B2
(en)
|
2001-07-25 |
2005-12-20 |
Amgen Inc. |
Substituted piperidines and methods of use
|
|
US7115607B2
(en)
|
2001-07-25 |
2006-10-03 |
Amgen Inc. |
Substituted piperazinyl amides and methods of use
|
|
CA2454830C
(en)
|
2001-07-26 |
2010-02-02 |
Schering Corporation |
Substituted urea neuropeptide y y5 receptor antagonists
|
|
WO2003011267A1
(fr)
|
2001-07-31 |
2003-02-13 |
The Nisshin Oillio, Ltd. |
Medicaments anti-obesite et ses substances
|
|
GB0119172D0
(en)
|
2001-08-06 |
2001-09-26 |
Melacure Therapeutics Ab |
Phenyl pyrrole derivatives
|
|
WO2003014113A1
(en)
|
2001-08-06 |
2003-02-20 |
Glenmark Pharmaceuticals Limited |
Novel benzopyran compounds and process for their preparation and use
|
|
MXPA04001144A
(es)
|
2001-08-07 |
2004-07-08 |
Banyu Pharma Co Ltd |
Compuestos espiro.
|
|
CA2456964A1
(en)
|
2001-08-08 |
2003-02-20 |
Merck & Co., Inc. |
Melanin-concentrating hormone antagonists
|
|
IL160304A0
(en)
|
2001-08-10 |
2004-07-25 |
Nippon Chemiphar Co |
ACTIVATOR FOR PEROXISOME PROLIFERATOR-RESPONSIVE RECEPTOR delta
|
|
EP1444224B1
(en)
|
2001-08-14 |
2006-05-03 |
Eli Lilly And Company |
3-substituted oxindole beta-3 agonists
|
|
WO2003016307A1
(en)
|
2001-08-14 |
2003-02-27 |
Eli Lilly And Company |
β3 ADRENERGIC AGONISTS
|
|
SE0102764D0
(sv)
|
2001-08-17 |
2001-08-17 |
Astrazeneca Ab |
Compounds
|
|
US7371777B2
(en)
|
2001-08-17 |
2008-05-13 |
Eisai Co., Ltd. |
Cyclic compound and PPAR agonist
|
|
DE10139416A1
(de)
|
2001-08-17 |
2003-03-06 |
Aventis Pharma Gmbh |
Aminoalkyl substituierte aromatische Bicyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
US20030092041A1
(en)
|
2001-08-23 |
2003-05-15 |
Millennium Pharmaceuticals, Inc. |
Novel use for muscarinic receptor M5 in the diagnosis and treatment of metabolic disorders
|
|
CN1520314A
(zh)
|
2001-08-24 |
2004-08-11 |
帝人株式会社 |
含有食糜酶抑制剂和ace抑制剂作为有效成分的药物
|
|
EP1421077A4
(en)
|
2001-08-31 |
2004-11-17 |
Univ Connecticut |
NEW PYRAZOLANALOGS ON CANNABINOID RECEPTORS
|
|
GB0121941D0
(en)
|
2001-09-11 |
2001-10-31 |
Astrazeneca Ab |
Chemical compounds
|
|
US6915444B2
(en)
|
2001-09-12 |
2005-07-05 |
Rockwell Automation Technologies, Inc. |
Network independent safety protocol for industrial controller using data manipulation techniques
|
|
EP1426370A4
(en)
|
2001-09-13 |
2009-12-23 |
Nisshin Pharma Inc |
PROPANOLAMINE DERIVATIVE WITH 1,4-BENZODIOXANRING
|
|
US6869975B2
(en)
|
2001-09-14 |
2005-03-22 |
Tularik Inc. |
Linked biaryl compounds
|
|
EP1434765B1
(en)
|
2001-09-14 |
2009-12-02 |
High Point Pharmaceuticals, LLC |
Substituted piperidines with selective binding to histamine h3-receptor
|
|
EP1426366A4
(en)
|
2001-09-14 |
2004-12-08 |
Mitsubishi Pharma Corp |
THIAZOLIDE DERIVATIVES AND THEIR MEDICAL USE
|
|
CA2459454A1
(en)
|
2001-09-14 |
2003-03-27 |
Bayer Pharmaceuticals Corporation |
Benzofuran and dihydrobenzofuran derivatives useful as beta-3 adrenoreceptor agonists
|
|
WO2003024928A2
(en)
|
2001-09-14 |
2003-03-27 |
Novo Nordisk A/S |
Novel aminoazetidine, -pyrrolidine and -piperidine derivatives
|
|
FR2829765A1
(fr)
|
2001-09-14 |
2003-03-21 |
Lipha |
Derives imidazolylalkoxylarylalcanoiques leurs applications en therapeutique
|
|
AU2002331311A1
(en)
|
2001-09-19 |
2003-04-01 |
Novo Nordisk A/S |
Heterocyclic compounds that are inhibitors of the enzyme dpp-iv
|
|
WO2003024447A1
(en)
|
2001-09-20 |
2003-03-27 |
Smithkline Beecham Corporation |
Inhibitors of glycogen synthase kinase-3
|
|
AU2002333852B2
(en)
|
2001-09-21 |
2006-07-13 |
Solvay Pharmaceuticals B.V. |
Novel 4,5-dihydro-1H-pyrazole derivativeshaving CB1-antagonistic activity
|
|
CN1529595A
(zh)
|
2001-09-21 |
2004-09-15 |
������ҩ������˾ |
具有效cb1-拮抗活性的4,5-2氢-1h-吡唑衍生物
|
|
TWI231757B
(en)
|
2001-09-21 |
2005-05-01 |
Solvay Pharm Bv |
1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
|
|
US6509367B1
(en)
|
2001-09-22 |
2003-01-21 |
Virginia Commonwealth University |
Pyrazole cannabinoid agonist and antagonists
|
|
WO2003026576A2
(en)
|
2001-09-24 |
2003-04-03 |
Board Of Supervisors Of Louisiana State Universityand Agricultural And Mechanical College |
Induction of brown adipocytes by transcription factor nfe2l2
|
|
UY27450A1
(es)
|
2001-09-24 |
2003-04-30 |
Bayer Corp |
Preparación y uso de derivados de imidazol para el tratamiento de la obesidad
|
|
JP2005504100A
(ja)
|
2001-09-24 |
2005-02-10 |
バイエル・フアーマシユーチカルズ・コーポレーシヨン |
肥満の治療のための１，５，６，７−テトラヒドロピロロ［３，２−ｃ］ピリジン誘導体の製造法および使用
|
|
BR0212985A
(pt)
|
2001-09-24 |
2005-08-30 |
Imp College Innovations Ltd |
Uso de pyy ou de um agonista do mesmo na preparação de medicamentos para tratamento de distúrbios associados com excesso de peso
|
|
JP2005532982A
(ja)
|
2001-09-24 |
2005-11-04 |
バイエル・フアーマシユーチカルズ・コーポレーシヨン |
肥満の処置のためのピロール誘導体の製造及び使用
|
|
KR20040041177A
(ko)
|
2001-09-26 |
2004-05-14 |
바이엘 파마슈티칼스 코포레이션 |
당뇨병 치료제로서의 1,6-나프티리딘 유도체
|
|
US6787558B2
(en)
|
2001-09-28 |
2004-09-07 |
Hoffmann-La Roche Inc. |
Quinoline derivatives
|
|
US7544690B2
(en)
|
2001-10-01 |
2009-06-09 |
Taisho Pharmaceutical Co., Ltd. |
MCH receptor antagonists
|
|
US7119110B2
(en)
|
2001-10-05 |
2006-10-10 |
Interhealth Nutraceuticals Incorporated |
Method and composition for preventing or reducing the symptoms of insulin resistance syndrome
|
|
WO2003031408A2
(en)
|
2001-10-08 |
2003-04-17 |
Eli Lilly And Company |
Tricyclic compounds useful for modulating lxr
|
|
WO2003031410A1
(en)
|
2001-10-09 |
2003-04-17 |
Neurocrine Biosciences, Inc. |
Ligands of melanocortin receptors and compositions and methods related thereto
|
|
GB0124463D0
(en)
|
2001-10-11 |
2001-12-05 |
Smithkline Beecham Plc |
Compounds
|
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
PT1445258E
(pt)
|
2001-10-12 |
2009-07-02 |
Nippon Chemiphar Co |
Activador para o receptor delta activado por proliferador de peroxissoma
|
|
ES2256560T3
(es)
|
2001-10-12 |
2006-07-16 |
Bayer Pharmaceuticals Corporation |
Heterociclos de 5 mienbros que contienen nitrogeno sustituidos con felino para el tratamiento de la obesidad.
|
|
US6573396B2
(en)
|
2001-10-12 |
2003-06-03 |
Exxonmobil Chemical Patents Inc. |
Co-production of dialkyl carbonates and diols with treatment of hydroxy alkyl carbonate
|
|
GB0124627D0
(en)
|
2001-10-15 |
2001-12-05 |
Smithkline Beecham Plc |
Novel compounds
|
|
PL369732A1
(en)
|
2001-10-16 |
2005-05-02 |
Dr.Reddy's Laboratories Ltd. |
Benzoxazine and benzothiazine derivatives and pharmaceutical compositions containing them
|
|
HUP0401837A2
(hu)
|
2001-10-17 |
2004-12-28 |
Novo Nordisk A/S |
Dikarbonsavszármazékok, előállításuk és gyógyászati alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények
|
|
DE10151390A1
(de)
|
2001-10-18 |
2003-05-08 |
Bayer Ag |
Essigsäurederivate
|
|
HUP0700124A2
(en)
|
2001-10-25 |
2007-06-28 |
Takeda Chemical Industries Ltd |
Quinoline compound
|
|
US6861440B2
(en)
|
2001-10-26 |
2005-03-01 |
Hoffmann-La Roche Inc. |
DPP IV inhibitors
|
|
US20050054696A1
(en)
|
2001-10-29 |
2005-03-10 |
Takeshi Nakamura |
Indole compounds and medicinal use thereof
|
|
US7342117B2
(en)
|
2001-10-30 |
2008-03-11 |
Astellas Pharma Inc. |
α-form or β-form crystal of acetanilide derivative
|
|
DE60222921T2
(de)
|
2001-11-01 |
2008-08-07 |
Janssen Pharmaceutica N.V. |
Amidderivate als inhibitoren der glycogensynthasekinase-3-beta
|
|
GB0126292D0
(en)
|
2001-11-01 |
2002-01-02 |
Smithkline Beecham Plc |
Compounds
|
|
BR0213792A
(pt)
|
2001-11-01 |
2004-12-07 |
Janssen Pharmaceutica Nv |
Heteroaril aminas como inibidores de glicogênio sintase cinase 3beta (inibidores de gsk3)
|
|
JP2005508978A
(ja)
|
2001-11-02 |
2005-04-07 |
ファイザー・プロダクツ・インク |
Ｐｄｅ９阻害薬によるインスリン抵抗性症候群及び２型糖尿病の治療
|
|
HN2002000317A
(es)
|
2001-11-02 |
2003-05-21 |
Pfizer |
Inhibidores de pde9 para tratamiento de trastornos cardiovasculares
|
|
EP1442028A4
(en)
|
2001-11-06 |
2009-11-04 |
Bristol Myers Squibb Co |
SUBSTITUTED ACID DERIVATIVES, WHICH APPRECIATE AS ANTIDIBILICS AND AGENTS AGAINST OBESITAS, AND METHODS
|
|
AU2002349705A1
(en)
|
2001-12-03 |
2003-06-17 |
Japan Tobacco Inc. |
Azole compound and medicinal use thereof
|
|
RU2374236C2
(ru)
|
2001-12-21 |
2009-11-27 |
Ново Нордиск А/С |
Амидные производные в качестве активаторов gk
|
|
WO2003057144A2
(en)
|
2001-12-26 |
2003-07-17 |
Guilford Pharmaceuticals |
Change inhibitors of dipeptidyl peptidase iv
|
|
US6727261B2
(en)
|
2001-12-27 |
2004-04-27 |
Hoffman-La Roche Inc. |
Pyrido[2,1-A]Isoquinoline derivatives
|
|
NZ571695A
(en)
|
2001-12-28 |
2010-02-26 |
Acadia Pharm Inc |
Spiroazacyclic compounds as monoamine receptor for modulating 5-HT2A receptor-mediated events
|
|
US20050113283A1
(en)
|
2002-01-18 |
2005-05-26 |
David Solow-Cordero |
Methods of treating conditions associated with an EDG-4 receptor
|
|
JP2005519915A
(ja)
|
2002-01-18 |
2005-07-07 |
セレテック・リミテッド・ライアビリティ・カンパニー |
Ｅｄｇ受容体に関連する症状の処置方法
|
|
CA2474702A1
(en)
|
2002-01-30 |
2003-08-07 |
Tularik Inc |
Heterocyclic arylsulfonamidobenzylic compounds
|
|
WO2003064404A1
(en)
|
2002-02-01 |
2003-08-07 |
Dainippon Pharmaceutical Co., Ltd. |
2-furancarboxylic acid hydrazides and pharmaceutical compositions containing the same
|
|
ATE369855T1
(de)
|
2002-02-25 |
2007-09-15 |
Lilly Co Eli |
Modulatoren von peroxisome proliferator- aktivierten rezeptoren
|
|
CN101838218A
(zh)
|
2002-02-28 |
2010-09-22 |
日本烟草产业株式会社 |
酯化合物及其医药用途
|
|
JP3813152B2
(ja)
|
2002-03-12 |
2006-08-23 |
メルク エンド カムパニー インコーポレーテッド |
置換アミド類
|
|
AU2003222278A1
(en)
*
|
2002-03-20 |
2003-10-08 |
Schering Aktiengesellschaft |
Menthol substituted antithrombotic pai-1 inhibitors
|
|
WO2003091216A1
(en)
|
2002-04-25 |
2003-11-06 |
Sumitomo Pharmaceuticals Co., Ltd. |
Novel piperidine derivative
|
|
AU2003227360A1
(en)
|
2002-04-25 |
2003-11-10 |
Yamanouchi Pharmaceutical Co., Ltd. |
Novel amide derivatives or salts thereof
|
|
AU2003230367A1
(en)
|
2002-05-10 |
2003-11-11 |
Neurocrine Biosciences, Inc. |
Substituted piperazine as melanocortin receptors ligands
|
|
DE10222034A1
(de)
|
2002-05-17 |
2003-11-27 |
Bayer Ag |
Tetrahydroisochinolin-Derivate
|
|
WO2003099793A1
(en)
|
2002-05-24 |
2003-12-04 |
Takeda Pharmaceutical Company Limited |
1,2-azole derivatives with hypoglycemic and hypolipidemic activity
|
|
JP4611019B2
(ja)
|
2002-06-19 |
2011-01-12 |
カロ バイオ エービー |
代謝異常治療のための新規な糖質コルチコイド受容体結合体
|
|
DE10229777A1
(de)
|
2002-07-03 |
2004-01-29 |
Bayer Ag |
Indolin-Phenylsulfonamid-Derivate
|
|
GB0215579D0
(en)
|
2002-07-05 |
2002-08-14 |
Astrazeneca Ab |
Chemical compounds
|
|
SE0202134D0
(sv)
|
2002-07-08 |
2002-07-08 |
Astrazeneca Ab |
Therapeutic agents
|
|
AU2003236827A1
(en)
|
2002-07-08 |
2004-01-23 |
Coloplast A/S |
Conduit device
|
|
ES2278197T3
(es)
|
2002-07-09 |
2007-08-01 |
Actelion Pharmaceuticals Ltd. |
Derivados de 7,8,9,10-tetrahidro-6h-azepino, 6,7,8,9-tetrahidro-pirido y 2,3-dihidro-2h-pirrolo(1,2-b)-quinazolinona.
|
|
WO2004007439A1
(ja)
|
2002-07-10 |
2004-01-22 |
Sumitomo Pharmaceuticals Co., Ltd. |
ビアリール誘導体
|
|
WO2004009806A1
(de)
|
2002-07-18 |
2004-01-29 |
Basf Aktiengesellschaft |
Nadh-abhängige cytochrom b5 reduktase als target für herbizide
|
|
DE10233817A1
(de)
|
2002-07-25 |
2004-02-12 |
Aventis Pharma Deutschland Gmbh |
Substituierte Diarylheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
KR20050025189A
(ko)
|
2002-07-27 |
2005-03-11 |
아스트라제네카 아베 |
화학 화합물
|
|
PL375441A1
(en)
|
2002-07-29 |
2005-11-28 |
F.Hoffmann-La Roche Ag |
Novel benzodioxoles
|
|
JP2004067629A
(ja)
|
2002-08-09 |
2004-03-04 |
Yamanouchi Pharmaceut Co Ltd |
ミトコンドリア機能活性化剤及び新規なベンゾイミダゾール誘導体
|
|
DE10238860A1
(de)
|
2002-08-24 |
2004-03-04 |
Bayerische Motoren Werke Ag |
Brennstoff-Zelle mit einer das Brenngas über der Elektroden-Oberfläche verteilenden perforierten Folie
|
|
US6849761B2
(en)
|
2002-09-05 |
2005-02-01 |
Wyeth |
Substituted naphthoic acid derivatives useful in the treatment of insulin resistance and hyperglycemia
|
|
WO2004022551A1
(ja)
|
2002-09-06 |
2004-03-18 |
Takeda Pharmaceutical Company Limited |
フランまたはチオフェン誘導体およびその医薬用途
|
|
CA2497794A1
(en)
|
2002-09-06 |
2004-03-18 |
Bayer Pharmaceuticals Corporation |
Modified glp-1 receptor agonists and their pharmacological methods of use
|
|
US20060040937A1
(en)
|
2002-09-18 |
2006-02-23 |
Glaxo Group Limited |
N-aroyl cyclic amines as orexin receptor antagonists
|
|
WO2004027047A2
(en)
|
2002-09-18 |
2004-04-01 |
Hanauske-Abel Hartmut M |
INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE AND USES THEREFOR
|
|
US7045527B2
(en)
|
2002-09-24 |
2006-05-16 |
Amgen Inc. |
Piperidine derivatives
|
|
AU2003275150A1
(en)
|
2002-09-25 |
2004-04-19 |
Neurogen Corporation |
Methods for preventing and treating obesity in patients with mc4 receptor mutations
|
|
JP2006509774A
(ja)
|
2002-10-03 |
2006-03-23 |
ノバルティス アクチエンゲゼルシャフト |
２型糖尿病の処置において有用なグルコキナーゼアクチベーターとしての置換（チアゾール−２−イル）−アミドまたはスルホンアミド
|
|
CN100354306C
(zh)
|
2002-10-11 |
2007-12-12 |
株式会社三和化学研究所 |
Glp－1衍生物及其经粘膜吸收的制剂
|
|
BR0315166A
(pt)
|
2002-10-11 |
2005-08-16 |
Astrazeneca Ab |
Uso de um composto ou de um sal farmaceuticamente aceitável do mesmo, composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, método para produzir um efeito inibidor de 11betahsd1 em um animal de sangue quente, tal como o homem, que necessita de tratamento
|
|
US20050270419A1
(en)
|
2002-10-11 |
2005-12-08 |
Koninklijke Philips Electronic N.V. |
Unit for and method of image conversion
|
|
JP4768265B2
(ja)
|
2002-10-15 |
2011-09-07 |
シンタ ファーマシューティカルズ コーポレーション |
新規化合物
|
|
KR20050059294A
(ko)
|
2002-10-24 |
2005-06-17 |
스테릭스 리미티드 |
11-베타-하이드록시 스테로이드 데하이드로게나제 형태 1및 형태 2의 억제제
|
|
US6852748B1
(en)
|
2002-10-30 |
2005-02-08 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl]-pyrrolidine-2-carboxylic acid amide
|
|
WO2004041795A1
(en)
|
2002-10-30 |
2004-05-21 |
Guilford Pharmaceuticals Inc. |
Novel inhibitors of dipeptidyl peptidase iv
|
|
DE10250743A1
(de)
|
2002-10-31 |
2004-05-19 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Amid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
|
|
FR2846656B1
(fr)
|
2002-11-05 |
2004-12-24 |
Servier Lab |
Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
GB0225944D0
(en)
|
2002-11-06 |
2002-12-11 |
Glaxo Group Ltd |
Novel compounds
|
|
AU2003276458A1
(en)
|
2002-11-07 |
2004-06-07 |
Astrazeneca Ab |
2-oxo-ethanesulfonamide derivates
|
|
GB0225986D0
(en)
|
2002-11-07 |
2002-12-11 |
Astrazeneca Ab |
Chemical compounds
|
|
DE10251927A1
(de)
|
2002-11-08 |
2004-05-19 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
AU2003277576A1
(en)
|
2002-11-08 |
2004-06-07 |
Takeda Pharmaceutical Company Limited |
Receptor function controlling agent
|
|
AU2003294249A1
(en)
|
2002-11-08 |
2004-06-03 |
Trimeris, Inc. |
Hetero-substituted benzimidazole compounds and antiviral uses thereof
|
|
US20050143449A1
(en)
|
2002-11-15 |
2005-06-30 |
The Salk Institute For Biological Studies |
Non-steroidal farnesoid X receptor modulators and methods for the use thereof
|
|
BR0316327A
(pt)
|
2002-11-18 |
2005-09-27 |
Pfizer Prod Inc |
Amidas cìclicas fluorinadas inibidoras de dipeptidilpeptidase iv
|
|
GB0226931D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0226930D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
AU2003281978A1
(en)
|
2002-11-22 |
2004-06-18 |
Boehringer Ingelheim International Gmbh |
2,5-diketopiperazines for the treatment of obesity
|
|
WO2004048532A2
(en)
|
2002-11-25 |
2004-06-10 |
Gni Usa |
Inferring gene regulatory networks from time-ordered gene expression data using differential equations
|
|
GB0227813D0
(en)
|
2002-11-29 |
2003-01-08 |
Astrazeneca Ab |
Chemical compounds
|
|
UY28103A1
(es)
|
2002-12-03 |
2004-06-30 |
Boehringer Ingelheim Pharma |
Nuevas imidazo-piridinonas sustituidas, su preparación y su empleo como medicacmentos
|
|
CA2508914A1
(en)
|
2002-12-04 |
2004-06-17 |
Gene Logic Inc. |
Modulators of melanocortin receptor
|
|
BR0316948A
(pt)
|
2002-12-11 |
2005-10-18 |
Lilly Co Eli |
Composto, formulação farmacêutica, e, uso de um composto
|
|
JP2004196702A
(ja)
|
2002-12-18 |
2004-07-15 |
Yamanouchi Pharmaceut Co Ltd |
新規なアミド誘導体又はその塩
|
|
WO2004056744A1
(en)
|
2002-12-23 |
2004-07-08 |
Janssen Pharmaceutica N.V. |
Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
|
|
US20040209928A1
(en)
|
2002-12-30 |
2004-10-21 |
Ravi Kurukulasuriya |
Glucagon receptor antagonists/inverse agonists
|
|
WO2004063194A1
(en)
|
2003-01-06 |
2004-07-29 |
Eli Lilly And Company |
Heteroaryl compounds
|
|
JP4716734B2
(ja)
|
2003-01-06 |
2011-07-06 |
イーライ リリー アンド カンパニー |
グルコキナーゼ活性化物質としての置換されたアリールシクロプロピルアセトアミド
|
|
DE10301788B4
(de)
|
2003-01-20 |
2005-08-25 |
Aventis Pharma Deutschland Gmbh |
Pharmazeutische Verwendung von Pyrimido[5,4-e][1,2,4]triazin-5,7-dionen
|
|
TW200503994A
(en)
|
2003-01-24 |
2005-02-01 |
Novartis Ag |
Organic compounds
|
|
EP1595866B1
(en)
|
2003-01-31 |
2016-06-08 |
Sanwa Kagaku Kenkyusho Co., Ltd. |
Cyanopyrrolidines useful for the treatment of inter alia metabolic syndrome
|
|
US6759546B1
(en)
|
2003-02-04 |
2004-07-06 |
Allergan, Inc. |
3,5-di-iso-propyl-heptatrienoic acid derivatives having serum glucose reducing activity
|
|
WO2004072041A1
(en)
|
2003-02-12 |
2004-08-26 |
Care X S.A. |
Tetrahydroquinolines as agonists of liver- x receptors
|
|
CN1747936A
(zh)
|
2003-02-12 |
2006-03-15 |
特兰斯泰克制药公司 |
作为治疗试剂的取代吡咯衍生物
|
|
WO2004071454A2
(en)
|
2003-02-13 |
2004-08-26 |
Guilford Pharmaceuticals Inc. |
Substituted azetidine compounds as inhibitors of dipeptidyl peptidase iv
|
|
US20050154011A1
(en)
|
2003-02-20 |
2005-07-14 |
The Procter & Gamble Company |
Tetrahydroisoquinolnyl sulfamic acids
|
|
FR2851563B1
(fr)
|
2003-02-26 |
2005-04-22 |
Sod Conseils Rech Applic |
Nouveaux derives de benzimidazole et d'imidazo-pyridine et leur utilisation en tant que medicament
|
|
US20040224992A1
(en)
|
2003-02-27 |
2004-11-11 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
EP1460069A1
(en)
|
2003-03-20 |
2004-09-22 |
MyoContract Ltd. |
Substituted cyclohexyl and piperidinyl derivatives as melanocortin-4 receptor modulators
|
|
CL2004000553A1
(es)
|
2003-03-20 |
2005-02-04 |
Actelion Pharmaceuticals Ltd |
Uso de compuestos derivados de guanidina como antagonistas del receptor de neuropeptido ff; compuestos derivados de guanidina; procedimientos de preparacion; y composicion farmaceutica que los comprende.
|
|
EP1468999A1
(en)
|
2003-03-20 |
2004-10-20 |
MyoContract Ltd. |
Substituted piperidine and piperazine derivatives as melanocortin-4 receptor modulators
|
|
US7531553B2
(en)
|
2003-03-21 |
2009-05-12 |
Amgen Inc. |
Heterocyclic compounds and methods of use
|
|
KR20050114242A
(ko)
|
2003-03-26 |
2005-12-05 |
액테리온 파마슈티칼 리미티드 |
오렉신 수용체 길항제로서 이용되는테트라하이드로이소퀴놀릴 아세트아마이드 유도체
|
|
FR2852957B1
(fr)
|
2003-03-31 |
2005-06-10 |
Sod Conseils Rech Applic |
Nouveaux derives d'imidazo-pyridine et leur utilisation en tant que medicament
|
|
CN100475793C
(zh)
|
2003-03-31 |
2009-04-08 |
大正制药株式会社 |
喹唑啉衍生物及其制备药物的用途
|
|
JP2004315511A
(ja)
|
2003-03-31 |
2004-11-11 |
Taisho Pharmaceut Co Ltd |
Ｍｃｈ受容体アンタゴニスト
|
|
US20040199842A1
(en)
|
2003-04-04 |
2004-10-07 |
Sartschev Ronald A. |
Test system with high accuracy time measurement system
|
|
WO2004089279A2
(en)
|
2003-04-08 |
2004-10-21 |
Yeda Research And Development Co. Ltd. |
Long-acting derivatives of pyy agonists
|
|
WO2004089918A1
(ja)
|
2003-04-09 |
2004-10-21 |
Japan Tobacco Inc. |
複素芳香５員環化合物及びその医薬用途
|
|
GB0308335D0
(en)
|
2003-04-10 |
2003-05-14 |
Novartis Ag |
Organic compounds
|
|
WO2004089415A2
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
COMBINATIONS OF AN 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND A GLUCOCORTICOID RECEPTOR AGONIST
|
|
EP1633354B1
(en)
|
2003-04-14 |
2008-01-23 |
The Institutes for Pharmaceutical Discovery, LLC |
N-(((((1,3-thiazol-2-yl)amino)carbonyl)phenyl)sulfonyl)phenylalanine derivatives and related compounds for the treatment of diabetes
|
|
MXPA05011176A
(es)
|
2003-04-17 |
2005-12-14 |
Pfizer Prod Inc |
Derivados de carboxamida como agentes antidiabeticos.
|
|
EP1633709A1
(en)
|
2003-04-30 |
2006-03-15 |
Pfizer Products Inc. |
Anti-diabetic agents
|
|
ATE453620T1
(de)
|
2003-05-01 |
2010-01-15 |
Vernalis Res Ltd |
Azetidincarboxamid-derivate zur verwendung zur behandlung von cb1-rezeptor-vermittelten krankheiten
|
|
AU2003902260A0
(en)
|
2003-05-09 |
2003-05-29 |
Fujisawa Pharmaceutical Co., Ltd. |
Dpp-iv inhibitor
|
|
US7119205B2
(en)
|
2003-05-16 |
2006-10-10 |
Abbott Laboratories |
Thienopyridones as AMPK activators for the treatment of diabetes and obesity
|
|
WO2004108674A1
(ja)
|
2003-06-05 |
2004-12-16 |
Kissei Pharmaceutical Co., Ltd. |
アミノアルコール誘導体、それを含有する医薬組成物およびそれらの用途
|
|
AU2003902828A0
(en)
|
2003-06-05 |
2003-06-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Dpp-iv inhibitor
|
|
AU2004252109B2
(en)
|
2003-06-11 |
2010-04-08 |
Merck Sharp & Dohme Corp. |
Substituted 3-alkyl and 3-alkenyl azetidine derivatives
|
|
WO2004111004A1
(en)
|
2003-06-12 |
2004-12-23 |
Novo Nordisk A/S |
Substituted piperazine carbamates for use as inhibitors of hormone sensitive lipase
|
|
GB0314049D0
(en)
|
2003-06-18 |
2003-07-23 |
Astrazeneca Ab |
Therapeutic agents
|
|
AU2004247615B2
(en)
|
2003-06-18 |
2008-02-21 |
Astrazeneca Ab |
2-substituted 5,6-diaryl-pyrazine derivatives as CB1 modulators
|
|
GB0314057D0
(en)
|
2003-06-18 |
2003-07-23 |
Astrazeneca Ab |
Therapeutic agents
|
|
GB0314261D0
(en)
|
2003-06-19 |
2003-07-23 |
Astrazeneca Ab |
Therapeutic agents
|
|
EP1644023A2
(en)
|
2003-06-19 |
2006-04-12 |
Eli Lilly And Company |
Melanocortin recptor 4(mc4) agonists and their uses
|
|
WO2005000301A1
(en)
|
2003-06-20 |
2005-01-06 |
F. Hoffmann-La Roche Ag |
2-aminobenzothiazoles as cb1 receptor inverse agonists
|
|
US7355049B2
(en)
|
2003-06-24 |
2008-04-08 |
Hoffmann-La Roche Inc. |
Biaryloxymethylarenecarboxylic acids as glycogen synthase activator
|
|
GB0314967D0
(en)
|
2003-06-26 |
2003-07-30 |
Hoffmann La Roche |
Piperazine derivatives
|
|
CA2530111A1
(en)
|
2003-06-27 |
2005-01-06 |
Tel-Aviv University Future Technology Development L.P. |
Glycogen synthase kinase-3 inhibitors
|
|
US20060148805A1
(en)
|
2003-07-01 |
2006-07-06 |
Meng Hsin Chen |
Opthalmic compositions for treating ocular hypertension
|
|
WO2005009956A1
(en)
|
2003-07-21 |
2005-02-03 |
Smithkline Beecham Corporation |
(2s,4s)-4-fluoro-1-[4-fluoro-beta-(4-fluorophenyl)-l-phenylalanyl]-2-pyrrolidinecarbonitrile p-toluenesulfonic acid salt and anhydrous crystalline forms thereof
|
|
JP2005042839A
(ja)
|
2003-07-23 |
2005-02-17 |
Iseki & Co Ltd |
作業車両の変速制御装置
|
|
CA2532800C
(en)
|
2003-07-23 |
2013-06-18 |
Exelixis, Inc. |
Anaplastic lymphoma kinase modulators and methods of use
|
|
US7008953B2
(en)
|
2003-07-30 |
2006-03-07 |
Agouron Pharmaceuticals, Inc. |
3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
|
|
US7452862B2
(en)
|
2003-07-31 |
2008-11-18 |
Tranzyme Pharma, Inc. |
Conformationally-controlled biologically active macrocyclic small molecules as motilin antagonists or ghrelin agonists
|
|
GB0318464D0
(en)
|
2003-08-07 |
2003-09-10 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0318463D0
(en)
|
2003-08-07 |
2003-09-10 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2005020892A2
(en)
|
2003-08-08 |
2005-03-10 |
Mitochroma Research, Inc. |
Pharmaceutical compositions and methods for metabolic modulation
|
|
WO2005014592A1
(en)
|
2003-08-12 |
2005-02-17 |
F. Hoffmann-La Roche Ag |
2-amino-5-benzoylthiazole npy antagonists
|
|
US7326706B2
(en)
|
2003-08-15 |
2008-02-05 |
Bristol-Myers Squibb Company |
Pyrazine modulators of cannabinoid receptors
|
|
US20050148643A1
(en)
|
2003-08-19 |
2005-07-07 |
Agouron Pharmaceuticals, Inc. |
Carbamate compositions and methods fo rmodulating the activity of the CHK1 enzyme
|
|
WO2005019168A2
(en)
|
2003-08-20 |
2005-03-03 |
Pfizer Products Inc. |
Fluorinated lysine derivatives as dipeptidyl peptidase iv inhibitors
|
|
CN1871029A
(zh)
|
2003-08-22 |
2006-11-29 |
帝人制药株式会社 |
含有类糜蛋白酶抑制剂作为有效成分的药物
|
|
TWI290140B
(en)
|
2003-08-25 |
2007-11-21 |
Schering Corp |
2-Substituted benzimidazole derivatives as selective melanin concentrating hormone receptor antagonists for thr treatment of obesity and related disorders
|
|
EP1661897B1
(en)
|
2003-08-26 |
2013-12-04 |
Teijin Pharma Limited |
Pyrrolopyrimidinone derivative
|
|
WO2005023762A1
(en)
|
2003-09-04 |
2005-03-17 |
Abbott Laboratories |
Pyrrolidine-2-carbonitrile derivatives and their use as inhibitors of dipeptidyl peptidase-iv (dpp-iv)
|
|
WO2005028624A2
(en)
|
2003-09-15 |
2005-03-31 |
Plexxikon, Inc. |
Molecular scaffolds for kinase ligand development
|
|
JP2007507533A
(ja)
*
|
2003-10-02 |
2007-03-29 |
シェーリング コーポレイション |
肥満および関連障害の処置のための、選択的メラニン凝集ホルモンレセプターアンタゴニストとしてのアミノベンズイミダゾール
|
|
US20050107374A1
(en)
|
2003-10-21 |
2005-05-19 |
Amgen Inc. |
Substituted heterocyclic compounds and methods of use
|
|
US7714009B2
(en)
|
2003-10-31 |
2010-05-11 |
Takeda Pharmaceutical Company Limited |
Nitrogen-containing fused heterocyclic compounds
|
|
US8969372B2
(en)
|
2003-11-14 |
2015-03-03 |
Aptose Boisciences Inc. |
Aryl imidazoles and their use as anti-cancer agents
|
|
US7829552B2
(en)
|
2003-11-19 |
2010-11-09 |
Metabasis Therapeutics, Inc. |
Phosphorus-containing thyromimetics
|
|
TW200522944A
(en)
|
2003-12-23 |
2005-07-16 |
Lilly Co Eli |
CB1 modulator compounds
|
|
NZ548208A
(en)
|
2004-02-12 |
2010-09-30 |
Transtech Pharma Inc |
Substituted azole derivatives, compositions, and methods of use
|
|
CA2555824C
(en)
|
2004-02-13 |
2011-06-07 |
Banyu Pharmaceutical Co., Ltd. |
Fused-ring 4-oxopyrimidine derivative
|
|
US7393847B2
(en)
*
|
2004-03-13 |
2008-07-01 |
Boehringer Ingleheim International Gmbh |
Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions
|
|
AU2005233160B2
(en)
|
2004-04-13 |
2011-06-02 |
Merck Sharp & Dohme Corp. |
CETP inhibitors
|
|
US7097961B2
(en)
|
2004-05-17 |
2006-08-29 |
Agfa Gevaert |
Stabilizers for use in substantially light-insensitive thermographic recording materials
|
|
US7687638B2
(en)
|
2004-06-04 |
2010-03-30 |
Takeda San Diego, Inc. |
Dipeptidyl peptidase inhibitors
|
|
WO2005121132A1
(ja)
|
2004-06-11 |
2005-12-22 |
Shionogi & Co., Ltd. |
抗ｈｃｖ作用を有する縮合ヘテロ環化合物
|
|
DE102004028862A1
(de)
*
|
2004-06-15 |
2005-12-29 |
Merck Patent Gmbh |
3-Aminoindazole
|
|
DOP2005000123A
(es)
|
2004-07-02 |
2011-07-15 |
Merck Sharp & Dohme |
Inhibidores de cetp
|
|
ATE539745T1
(de)
|
2004-08-19 |
2012-01-15 |
Univ Tel Aviv Future Tech Dev |
Zusammensetzungen zur behandlung von amyloid- assoziierten erkrankungen
|
|
GB0420719D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
EP1810677A1
(en)
*
|
2004-10-08 |
2007-07-25 |
Takeda Pharmaceutical Company Limited |
Receptor function regulating agent
|
|
AU2005300835B2
(en)
|
2004-11-02 |
2011-01-20 |
Dsm Ip Assets B.V. |
Additive for UV-sunscreen preparations
|
|
US8003806B2
(en)
|
2004-11-12 |
2011-08-23 |
OSI Pharmaceuticals, LLC |
Integrin antagonists useful as anticancer agents
|
|
US20090286838A1
(en)
|
2004-12-06 |
2009-11-19 |
Newsouth Innovations Pty Limited |
Treatment for cancer
|
|
US7429608B2
(en)
|
2005-01-20 |
2008-09-30 |
Amgen Inc. |
Benzo[d]imidazol analogs as vanilloid receptor ligands and their use in treatments
|
|
WO2006094209A2
(en)
|
2005-03-03 |
2006-09-08 |
Sirtris Pharmaceuticals, Inc. |
N-benzimidazolylalkyl-substituted amide sirtuin modulators
|
|
CA2600570C
(en)
|
2005-03-14 |
2011-12-06 |
Transtech Pharma, Inc. |
Benzazole derivatives, compositions, and methods of use as .beta.-secretase inhibitors
|
|
TWI370820B
(en)
|
2005-04-27 |
2012-08-21 |
Takeda Pharmaceutical |
Fused heterocyclic compounds
|
|
BRPI0609464A2
(pt)
|
2005-05-23 |
2010-04-13 |
Japan Tobacco Inc |
composto de pirazol e agente terapêutico para diabetes compreendendo o mesmo
|
|
JP2008542258A
(ja)
|
2005-05-25 |
2008-11-27 |
アクテリオン ファーマシューティカルズ リミテッド |
新規抗生物質誘導体
|
|
JP2009500351A
(ja)
|
2005-07-04 |
2009-01-08 |
ドクター レディズ ラボラトリーズ リミテッド |
Ａｍｐｋアクチベータとしてのチアゾール誘導体
|
|
CN101218208A
(zh)
|
2005-07-11 |
2008-07-09 |
出光兴产株式会社 |
含氮杂环衍生物以及使用其的有机电致发光元件
|
|
KR20080028425A
(ko)
|
2005-07-11 |
2008-03-31 |
이데미쓰 고산 가부시키가이샤 |
전자흡인성 치환기를 갖는 질소 함유 헤테로환 유도체 및그것을 사용한 유기 전기발광 소자
|
|
JP2007039406A
(ja)
|
2005-08-05 |
2007-02-15 |
Idemitsu Kosan Co Ltd |
含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子
|
|
JP2007153778A
(ja)
|
2005-12-02 |
2007-06-21 |
Idemitsu Kosan Co Ltd |
含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子
|
|
EP1976835A2
(en)
|
2006-01-13 |
2008-10-08 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
KR101472248B1
(ko)
|
2006-02-10 |
2014-12-16 |
서미트 코포레이션 피엘씨 |
뒤시엔느 근이영양증의 치료
|
|
US7820821B2
(en)
|
2006-02-10 |
2010-10-26 |
Transtech Pharma, Inc. |
Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors
|
|
FR2903695B1
(fr)
|
2006-07-13 |
2008-10-24 |
Merck Sante Soc Par Actions Si |
Utilisation de derives d'imidazole activateurs de l'ampk, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
AU2007272795A1
(en)
|
2006-07-14 |
2008-01-17 |
Merck & Co., Inc. |
2-substituted proline bis-amide orexin receptor antagonists
|
|
EP1878724A1
(en)
|
2006-07-15 |
2008-01-16 |
sanofi-aventis |
A regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles
|
|
TW200840110A
(en)
|
2006-11-20 |
2008-10-01 |
Idemitsu Kosan Co |
Organic electroluminescent device
|
|
KR20090127867A
(ko)
|
2006-12-05 |
2009-12-14 |
네이셔널 치아오 텅 유니버시티 |
인다졸 화합물
|
|
PE20090510A1
(es)
|
2007-08-03 |
2009-05-22 |
Summit Corp Plc |
Combinaciones de drogas para el tratamiento de la distrofia muscular de duchenne
|
|
CN101959404B
(zh)
|
2008-02-04 |
2015-12-02 |
墨丘瑞医疗有限公司 |
单磷酸腺苷活化蛋白激酶调节剂
|
|
EP3924343A1
(en)
|
2008-09-26 |
2021-12-22 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
US8410284B2
(en)
|
2008-10-22 |
2013-04-02 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
|
WO2010051176A1
(en)
|
2008-10-29 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
CA2741672A1
(en)
|
2008-10-31 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
AU2011218830B2
(en)
|
2010-02-25 |
2014-07-24 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
CA2826649C
(en)
|
2011-02-25 |
2016-07-26 |
Merck Sharp & Dohme Corp. |
Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
|