JP2013520502A5 - - Google Patents

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JP2013520502A5
JP2013520502A5 JP2012555064A JP2012555064A JP2013520502A5 JP 2013520502 A5 JP2013520502 A5 JP 2013520502A5 JP 2012555064 A JP2012555064 A JP 2012555064A JP 2012555064 A JP2012555064 A JP 2012555064A JP 2013520502 A5 JP2013520502 A5 JP 2013520502A5
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alkyl
substituted
unsubstituted
halogen
pharmaceutically acceptable
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JP2012555064A
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Priority claimed from PCT/US2011/025585 external-priority patent/WO2011106273A1/en
Publication of JP2013520502A publication Critical patent/JP2013520502A/ja
Publication of JP2013520502A5 publication Critical patent/JP2013520502A5/ja
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JP2012555064A 2010-02-25 2011-02-21 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体 Withdrawn JP2013520502A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30790910P 2010-02-25 2010-02-25
US61/307,909 2010-02-25
PCT/US2011/025585 WO2011106273A1 (en) 2010-02-25 2011-02-21 Novel cyclic benzimidazole derivatives useful anti-diabetic agents

Publications (2)

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JP2013520502A JP2013520502A (ja) 2013-06-06
JP2013520502A5 true JP2013520502A5 (enExample) 2013-11-28

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JP2012555064A Withdrawn JP2013520502A (ja) 2010-02-25 2011-02-21 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体

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US (1) US8895596B2 (enExample)
EP (1) EP2538784B1 (enExample)
JP (1) JP2013520502A (enExample)
AU (1) AU2011218830B2 (enExample)
CA (1) CA2786314A1 (enExample)
WO (1) WO2011106273A1 (enExample)

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ES2755087T3 (es) 2012-08-22 2020-04-21 Merck Sharp & Dohme Derivados de benzimidazol hexahidrofuro[3,2-b]furano útiles como activadores de proteína cinasa activada por AMP
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TWI644899B (zh) 2013-02-04 2018-12-21 健生藥品公司 Flap調節劑
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JP6579550B2 (ja) 2014-08-27 2019-09-25 塩野義製薬株式会社 Ampk活性化作用を有するアザインドール誘導体
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JPWO2017146186A1 (ja) 2016-02-26 2018-12-20 塩野義製薬株式会社 Ampk活性化作用を有する5−フェニルアザインドール誘導体
US10406140B2 (en) 2016-05-20 2019-09-10 Shionogi & Co., Ltd. 5-substituted benzimidazole and 5-substituted azabenzimidazole derivative both having AMPK activation effect
EP3500558B1 (en) * 2016-08-19 2022-11-02 Rigel Pharmaceuticals, Inc. Benzimidazole direct ampk activators
JP7668509B2 (ja) * 2016-11-11 2025-04-25 サギメット バイオサイエンシーズ インコーポレイテッド 脂質合成の複素環式モジュレーター
CN116323608A (zh) 2020-05-19 2023-06-23 卡尔优普公司 Ampk活化剂
EP4172162A4 (en) * 2020-06-26 2024-08-07 Kallyope, Inc. AMPK ACTIVATORS
US12404348B2 (en) 2021-11-19 2025-09-02 The Brigham And Women's Hospital, Inc. Bifunctional chimeric molecules for labeling of kinases with target binding moieties and methods of use thereof
WO2023097189A1 (en) * 2021-11-23 2023-06-01 Kallyope, Inc. Ampk activators
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