|
US3536809A
(en)
|
1969-02-17 |
1970-10-27 |
Alza Corp |
Medication method
|
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
|
US3630200A
(en)
|
1969-06-09 |
1971-12-28 |
Alza Corp |
Ocular insert
|
|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US3916899A
(en)
|
1973-04-25 |
1975-11-04 |
Alza Corp |
Osmotic dispensing device with maximum and minimum sizes for the passageway
|
|
US3914250A
(en)
|
1974-08-01 |
1975-10-21 |
American Home Prod |
1,4-Diazepino{8 6,5,4-jk{9 carbazoles
|
|
US4008719A
(en)
|
1976-02-02 |
1977-02-22 |
Alza Corporation |
Osmotic system having laminar arrangement for programming delivery of active agent
|
|
JPS608117B2
(ja)
|
1977-02-08 |
1985-02-28 |
財団法人微生物化学研究会 |
新生理活性物質エステラスチンおよびその製造法
|
|
DE2928485A1
(de)
|
1979-07-14 |
1981-01-29 |
Bayer Ag |
Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
|
|
JPS57151944A
(en)
|
1981-03-16 |
1982-09-20 |
Fuji Photo Film Co Ltd |
Color photosensitive silver halide material
|
|
ZA821577B
(en)
|
1981-04-06 |
1983-03-30 |
Boots Co Plc |
Therapeutic agents
|
|
US4452813A
(en)
|
1981-05-22 |
1984-06-05 |
Taiho Pharmaceutical Company Limited |
Sulfonate derivatives, process for preparing same and antilipemic compositions containing the derivative
|
|
JPS58193541A
(ja)
|
1982-05-07 |
1983-11-11 |
Konishiroku Photo Ind Co Ltd |
熱現像画像記録材料
|
|
JPH0245181B2
(ja)
|
1983-03-16 |
1990-10-08 |
Fuji Photo Film Co Ltd |
Netsugenzokaraakankozairyo
|
|
GB8313320D0
(en)
|
1983-05-14 |
1983-06-22 |
Ciba Geigy Ag |
Coating compositions
|
|
GB8313321D0
(en)
|
1983-05-14 |
1983-06-22 |
Ciba Geigy Ag |
Preparation of mercaptan substituted carboxylic acids
|
|
GB8313322D0
(en)
|
1983-05-14 |
1983-06-22 |
Ciba Geigy Ag |
Heterocyclic-(cyclo)aliphatic carboxylic acids
|
|
CA1247547A
(en)
|
1983-06-22 |
1988-12-28 |
Paul Hadvary |
Leucine derivatives
|
|
GB8412064D0
(en)
|
1984-05-11 |
1984-06-20 |
Ciba Geigy Ag |
Compositions containing heterocyclic corrosion inhibitors
|
|
GB8412063D0
(en)
|
1984-05-11 |
1984-06-20 |
Ciba Geigy Ag |
Compositions containing heterocyclic corrosion inhibitors
|
|
GB8412065D0
(en)
|
1984-05-11 |
1984-06-20 |
Ciba Geigy Ag |
Preparation of carboxylic acid derivatives
|
|
US4851423A
(en)
|
1986-12-10 |
1989-07-25 |
Schering Corporation |
Pharmaceutically active compounds
|
|
IE61928B1
(en)
|
1988-11-29 |
1994-11-30 |
Boots Co Plc |
Treatment of obesity
|
|
US5391571A
(en)
|
1989-11-15 |
1995-02-21 |
American Home Products Corporation |
Cholesterol ester hydrolase inhibitors
|
|
US5112820A
(en)
|
1990-03-05 |
1992-05-12 |
Sterling Drug Inc. |
Anti-glaucoma compositions containing 2- and 3-aminomethyl-6-arylcarbonyl- or 6-phenylthio-2,3-dihydropyrrolo-(1,2,3-de)-1,4-benzoxazines and method of use thereof
|
|
US5081122A
(en)
|
1990-03-05 |
1992-01-14 |
Sterling Drug Inc. |
Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof
|
|
US4973587A
(en)
|
1990-03-08 |
1990-11-27 |
Sterling Drug Inc. |
3-arylcarbonyl-1-aminoalkyl-1H-indole-containing antiglaucoma method
|
|
US5013837A
(en)
|
1990-03-08 |
1991-05-07 |
Sterling Drug Inc. |
3-Arylcarbonyl-1H-indole-containing compounds
|
|
JPH0427854A
(ja)
|
1990-05-23 |
1992-01-30 |
Mitsubishi Heavy Ind Ltd |
レーザ分析装置
|
|
CA2102780C
(en)
|
1991-05-10 |
2007-01-09 |
Alfred P. Spada |
Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase
|
|
PT100905A
(pt)
|
1991-09-30 |
1994-02-28 |
Eisai Co Ltd |
Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
|
|
FR2692575B1
(fr)
|
1992-06-23 |
1995-06-30 |
Sanofi Elf |
Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
US6472178B1
(en)
|
1998-02-27 |
2002-10-29 |
Regeneron Pharmaceuticals, Inc. |
Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
|
|
US5349056A
(en)
|
1992-10-09 |
1994-09-20 |
Regeneron Pharmaceuticals |
Modified ciliary neurotrophic factors
|
|
AU5118893A
(en)
|
1992-10-13 |
1994-05-09 |
Nippon Soda Co., Ltd. |
Oxazole and thiazole derivatives
|
|
US5451677A
(en)
|
1993-02-09 |
1995-09-19 |
Merck & Co., Inc. |
Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
|
|
US5292736A
(en)
|
1993-02-26 |
1994-03-08 |
Sterling Winthrop Inc. |
Morpholinoalkylindenes as antiglaucoma agents
|
|
JPH06298731A
(ja)
|
1993-04-13 |
1994-10-25 |
Fuji Photo Film Co Ltd |
複素環化合物の製造方法
|
|
DE4326151A1
(de)
|
1993-08-04 |
1995-02-09 |
Hoechst Ag |
Aromatische Verbindungen und ihre Verwendung in flüssigkristallinen Mischungen
|
|
CA2134192A1
(en)
|
1993-11-12 |
1995-05-13 |
Michael L. Denney |
5, 6-bicyclic glycoprotein iib/iiia antagonists
|
|
FR2714057B1
(fr)
|
1993-12-17 |
1996-03-08 |
Sanofi Elf |
Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.
|
|
IL113410A
(en)
|
1994-04-26 |
1999-11-30 |
Merck & Co Inc |
Substituted sulfonamides having an asymmetric center and pharmaceutical compositions containing them
|
|
US5705515A
(en)
|
1994-04-26 |
1998-01-06 |
Merck & Co., Inc. |
Substituted sulfonamides as selective β-3 agonists for the treatment of diabetes and obesity
|
|
US5945425A
(en)
|
1994-04-29 |
1999-08-31 |
G.D. Searle & Co. |
Method of using (H+ /K+)ATPase inhibitors as antiviral agents
|
|
BR9508177A
(pt)
|
1994-06-30 |
1997-09-02 |
Minnesota Mining & Mfg |
Material de impressão dental e processo para monitorar a cura do mesmo
|
|
PL321136A1
(en)
|
1994-11-07 |
1997-11-24 |
Pfizer |
Some substituted derivatives of bencylamine as a new class of specific ligands of neuropeptide y1
|
|
US5605886A
(en)
|
1995-01-31 |
1997-02-25 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5554727A
(en)
|
1995-01-31 |
1996-09-10 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
CA2211664A1
(en)
|
1995-01-31 |
1996-08-08 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5521283A
(en)
|
1995-01-31 |
1996-05-28 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5552524A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5552522A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5559208A
(en)
|
1995-01-31 |
1996-09-24 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
WO1996023514A1
(en)
|
1995-01-31 |
1996-08-08 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5552523A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
|
US5532237A
(en)
|
1995-02-15 |
1996-07-02 |
Merck Frosst Canada, Inc. |
Indole derivatives with affinity for the cannabinoid receptor
|
|
US5831115A
(en)
|
1995-04-21 |
1998-11-03 |
Abbott Laboratories |
Inhibitors of squalene synthase and protein farnesyltransferase
|
|
US20020006964A1
(en)
|
1995-05-16 |
2002-01-17 |
Young James W. |
Methods of using and compositions comprising (+) sibutramine optionally in combination with other pharmacologically active compounds
|
|
US5739106A
(en)
|
1995-06-07 |
1998-04-14 |
Rink; Timothy J. |
Appetite regulating compositions
|
|
WO1997010813A1
(en)
|
1995-09-18 |
1997-03-27 |
Ligand Pharmaceuticals Incorporated |
Ppar gamma antagonists for treating obesity
|
|
FR2741621B1
(fr)
|
1995-11-23 |
1998-02-13 |
Sanofi Sa |
Nouveaux derives de pyrazole, procede pour leur preparation et compositions pharmaceutiques en contenant
|
|
US6482927B1
(en)
|
1995-11-27 |
2002-11-19 |
Millennium Pharmaceuticals, Inc. |
Chimeric proteins comprising the extracellular domain of murine Ob receptor
|
|
WO1997020823A2
(en)
|
1995-12-01 |
1997-06-12 |
Novartis Ag |
2-amino quinazoline derivatives as npy receptor antagonists
|
|
WO1997020821A1
(en)
|
1995-12-01 |
1997-06-12 |
Novartis Ag |
Heteroaryl derivatives
|
|
AU7692896A
(en)
|
1995-12-01 |
1997-06-27 |
Novartis Ag |
Quinazolin-2,4-diazirines as NPY receptor antagonist
|
|
AU7626496A
(en)
|
1995-12-01 |
1997-06-27 |
Ciba-Geigy Ag |
Heteroaryl compounds
|
|
WO1997019682A1
(en)
|
1995-12-01 |
1997-06-05 |
Synaptic Pharmaceutical Corporation |
Aryl sulfonamide and sulfamide derivatives and uses thereof
|
|
TW432073B
(en)
|
1995-12-28 |
2001-05-01 |
Pfizer |
Pyrazolopyridine compounds
|
|
EP1011651B1
(en)
|
1996-02-02 |
2005-04-27 |
Merck & Co., Inc. |
Method of treating diabetes and related disease states
|
|
ES2217392T3
(es)
|
1996-02-02 |
2004-11-01 |
MERCK & CO., INC. |
Agentes antidiabeticos.
|
|
AU1856997A
(en)
|
1996-02-02 |
1997-08-22 |
Merck & Co., Inc. |
Method for raising hdl cholesterol levels
|
|
ATE236137T1
(de)
|
1996-02-02 |
2003-04-15 |
Merck & Co Inc |
Heterocyclische verbindungen als antidiabetische mittel und für die behandlung von fettleibigkeit
|
|
DE69723680T9
(de)
|
1996-02-02 |
2004-11-04 |
Merck & Co., Inc. |
Antidiabetische mittel
|
|
AU1618697A
(en)
|
1996-02-06 |
1997-08-28 |
Japan Tobacco Inc. |
Novel compounds and pharmaceutical use thereof
|
|
CA2257206A1
(en)
|
1996-06-07 |
1997-12-11 |
Gui-Bai Liang |
Oxadiazole benzenesulfonamides as selective .beta.3 agonists for the treatment of diabetes and obesity
|
|
EP0922028A1
(en)
|
1996-08-26 |
1999-06-16 |
Genetics Institute, Inc. |
Inhibitors of phospholipase enzymes
|
|
IT1288388B1
(it)
|
1996-11-19 |
1998-09-22 |
Angeletti P Ist Richerche Bio |
Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
|
|
CA2274594C
(en)
|
1996-12-16 |
2006-10-10 |
Banyu Pharmaceutical Co., Ltd. |
Aminopyrazole derivatives
|
|
JPH10237049A
(ja)
|
1996-12-24 |
1998-09-08 |
Nippon Chemiphar Co Ltd |
ベンズイソキサゾ−ル誘導体
|
|
US6100259A
(en)
|
1997-01-21 |
2000-08-08 |
Smithkline Beecham Corporation |
Cannabinoid receptor modulators
|
|
SK100099A3
(en)
|
1997-01-28 |
2000-05-16 |
Merck & Co Inc |
Thiazole benzenesulfonamides as 'beta'3 agonists for the treatment of diabetes and obesity
|
|
CN1982290A
(zh)
|
1997-02-04 |
2007-06-20 |
阿肯色大学评议会 |
杀菌的羧酰胺
|
|
EP0966436B1
(de)
|
1997-02-21 |
2002-12-11 |
Bayer Aktiengesellschaft |
Arylsulfonamide und analoga und ihre verwendung zur behandlung von neurodegenerativen erkrankungen
|
|
WO1998039342A1
(en)
|
1997-03-07 |
1998-09-11 |
Metabasis Therapeutics, Inc. |
Novel indole and azaindole inhibitors of fructose-1,6-bisphosphatase
|
|
ZA981936B
(en)
|
1997-03-07 |
1999-09-06 |
Metabasis Therapeutics Inc |
Novel benzimidazole inhibitors of fructose 1,6-bisphosphatase.
|
|
WO1998039344A1
(en)
|
1997-03-07 |
1998-09-11 |
Metabasis Therapeutics, Inc. |
Novel purine inhibitors of fructose-1,6-bisphosphatase
|
|
US5948777A
(en)
|
1997-03-18 |
1999-09-07 |
Smithkline Beecham Corporation |
Cannabinoid receptor agonists
|
|
FR2761265B1
(fr)
|
1997-03-28 |
1999-07-02 |
Sanofi Sa |
Composition pharmaceutique pour l'administration orale d'un derive du n-piperidino-3-pyrazolecarboxamide, de ses sels et de leurs solvates
|
|
FR2761266B1
(fr)
|
1997-03-28 |
1999-07-02 |
Sanofi Sa |
Composition pharmaceutique formee par granulation humide pour l'administration orale d'un derive du n-piperidino-3- pyrazolecarboxamide, de ses sels et de leurs solvates
|
|
DE69812096T2
(de)
|
1997-04-23 |
2003-10-30 |
Banyu Pharmaceutical Co., Ltd. |
Neuropeptid y rezeptorantagonisten
|
|
US6001836A
(en)
|
1997-05-28 |
1999-12-14 |
Bristol-Myers Squibb Company |
Dihydropyridine NPY antagonists: cyanoguanidine derivatives
|
|
PT994890E
(pt)
|
1997-06-10 |
2003-11-28 |
Glaxo Group Ltd |
Derivados de benzimidazole
|
|
SE9702457D0
(sv)
|
1997-06-26 |
1997-06-26 |
Pharmacia & Upjohn Ab |
Screening
|
|
JP2002507996A
(ja)
|
1997-07-03 |
2002-03-12 |
デュポン ファーマシューティカルズ カンパニー |
神経学的障害を治療するためのイミダゾピリミジン類およびイミダゾピリジン類
|
|
KR20010021696A
(ko)
|
1997-07-11 |
2001-03-15 |
미즈노 마사루 |
퀴놀린 화합물 및 그의 의약용도
|
|
US6440961B1
(en)
|
1997-10-27 |
2002-08-27 |
Dr. Reddy's Research Foundation |
Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
|
|
WO1999016758A1
(en)
|
1997-10-27 |
1999-04-08 |
Dr. Reddy's Research Foundation |
Novel heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them
|
|
WO1999019313A1
(en)
|
1997-10-27 |
1999-04-22 |
Dr. Reddy's Research Foundation |
Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
|
|
AU1887999A
(en)
|
1998-01-29 |
1999-08-16 |
Dr. Reddy's Research Foundation |
Novel alkanoic acids and their use in medicine, process for their preparation and pharmaceutical compositions containing them
|
|
CA2322163A1
(en)
|
1998-02-25 |
1999-09-02 |
John Mckew |
Inhibitors of phospholipase a2
|
|
US6312662B1
(en)
|
1998-03-06 |
2001-11-06 |
Metabasis Therapeutics, Inc. |
Prodrugs phosphorus-containing compounds
|
|
EP1060182B1
(en)
|
1998-03-06 |
2012-12-19 |
Metabasis Therapeutics, Inc. |
Novel prodrugs for phosphorus-containing compounds
|
|
CA2326606A1
(en)
|
1998-04-02 |
1999-10-14 |
Neurogen Corporation |
Aminoalkyl substituted 9h-pyridino[2,3-b]indole and 9h-pyrimidino[4,5-b]indole derivatives:crf1 and npy1 receptors
|
|
ID26128A
(id)
|
1998-04-29 |
2000-11-23 |
Ortho Mcneil Pharm Inc |
Senyawa-senyawa aminotetralin tersubstitusi-n sebagai ligan-ligan untuk reseptor neupeptida y y5 yang bermanfaat dalam pengobatan obesitas dan gangguan-gangguan lain
|
|
JP2002507543A
(ja)
|
1998-05-27 |
2002-03-12 |
ドクター・レディーズ・リサーチ・ファウンデーション |
二環系化合物、その製造方法およびそれらを含有する薬学的組成物
|
|
US6329395B1
(en)
|
1998-06-08 |
2001-12-11 |
Schering Corporation |
Neuropeptide Y5 receptor antagonists
|
|
WO1999064002A1
(en)
|
1998-06-11 |
1999-12-16 |
Merck & Co., Inc. |
Spiropiperidine derivatives as melanocortin receptor agonists
|
|
HUP0103256A3
(en)
|
1998-07-15 |
2002-05-28 |
Teijin Ltd |
Thiobenzimidazole derivatives and pharmaceutical compositions containing the compounds
|
|
HN1998000027A
(es)
|
1998-08-19 |
1999-06-02 |
Bayer Ip Gmbh |
Arilsulfonamidas y analagos
|
|
DE19837627A1
(de)
|
1998-08-19 |
2000-02-24 |
Bayer Ag |
Neue Aminosäureester von Arylsulfonamiden und Analoga
|
|
US6358951B1
(en)
|
1998-08-21 |
2002-03-19 |
Pfizer Inc. |
Growth hormone secretagogues
|
|
WO2000014095A1
(en)
|
1998-09-09 |
2000-03-16 |
Metabasis Therapeutics, Inc. |
Novel heteroaromatic inhibitors of fructose 1,6-bisphosphatase
|
|
AU5911499A
(en)
|
1998-09-10 |
2000-04-03 |
Millennium Pharmaceuticals, Inc. |
Leptin induced genes
|
|
US6337332B1
(en)
|
1998-09-17 |
2002-01-08 |
Pfizer Inc. |
Neuropeptide Y receptor antagonists
|
|
DE19844547C2
(de)
|
1998-09-29 |
2002-11-07 |
Aventis Pharma Gmbh |
Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
ATE457169T1
(de)
|
1998-10-15 |
2010-02-15 |
Imp Innovations Ltd |
Verbindungen für die behandlung von gewichtsverlust
|
|
AU6325599A
(en)
|
1998-10-21 |
2000-05-08 |
Dr. Reddy's Research Foundation |
New compounds, their preparation and use
|
|
US6353018B1
(en)
|
1998-10-21 |
2002-03-05 |
Novo Nordisk A/S |
Compounds, their preparation and use
|
|
EP1123269A1
(en)
|
1998-10-21 |
2001-08-16 |
Novo Nordisk A/S |
New compounds, their preparation and use
|
|
WO2000027845A1
(en)
|
1998-11-10 |
2000-05-18 |
Merck & Co., Inc. |
Spiro-indolines as y5 receptor antagonists
|
|
ES2161594B1
(es)
|
1998-12-17 |
2003-04-01 |
Servier Lab |
Nuevos derivados de la hidrazida, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
|
|
US6344481B1
(en)
|
1999-03-01 |
2002-02-05 |
Pfizer Inc. |
Thyromimetic antiobesity agents
|
|
IL145052A0
(en)
|
1999-03-05 |
2002-06-30 |
Metabasis Therapeutics Inc |
Novel phosphorus-containing prodrugs
|
|
WO2000054765A1
(en)
|
1999-03-19 |
2000-09-21 |
Knoll Gmbh |
Method of treating eating disorders
|
|
FR2792314B1
(fr)
|
1999-04-15 |
2001-06-01 |
Adir |
Nouveaux composes aminotriazoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
US6340683B1
(en)
|
1999-04-22 |
2002-01-22 |
Synaptic Pharmaceutical Corporation |
Selective NPY (Y5) antagonists (triazines)
|
|
DK1183245T3
(da)
|
1999-04-22 |
2007-09-24 |
Lundbeck & Co As H |
Selektive NPY(Y5)-antagonister
|
|
HK1041263A1
(zh)
|
1999-05-05 |
2002-07-05 |
Ortho-Mcneil Pharmaceutical, Inc. |
可用於治疗肥胖和其他疾病的3a,4,5,9b-四氢-1h-苯并[e]吲-2-基胺衍生的神经肽y受体配体
|
|
AU778393B2
(en)
|
1999-05-12 |
2004-12-02 |
Ortho-Mcneil Pharmaceutical, Inc. |
Pyrazole carboxamides useful for the treatment of obesity and other disorders
|
|
CA2377369A1
(en)
|
1999-06-04 |
2000-12-14 |
Merck & Co., Inc. |
Substituted piperidines as melanocortin-4 receptor agonists
|
|
CA2380866A1
(en)
|
1999-06-30 |
2001-01-11 |
Synaptic Pharmaceutical Corporation |
Selective npy (y5) antagonists
|
|
DK1192137T3
(da)
|
1999-06-30 |
2013-11-11 |
Amgen Inc |
Forbindelser til modulering af PPAR-gamma aktivitet
|
|
AU6000900A
(en)
|
1999-07-23 |
2001-02-13 |
Astrazeneca Uk Limited |
Carbazole derivatives and their use as neuropeptide y5 receptor ligands
|
|
HUP0202143A3
(en)
|
1999-07-28 |
2003-12-29 |
Ortho Mcneil Pharm Inc |
Amine and amide derivatives as ligands for the neuropeptide y y5 receptor pharmaceutical compositions containing them and their use
|
|
BR0012984A
(pt)
|
1999-08-04 |
2002-07-16 |
Millennium Pharm Inc |
Método para tratar um estado associado com o mc4-r em um mamìfero, composto de ligação ao mc4-r, e, composição farmacêutica
|
|
TWI279402B
(en)
|
1999-08-20 |
2007-04-21 |
Banyu Pharma Co Ltd |
Spiro compounds having NPY antagonistic activities and agents containing the same
|
|
WO2001021169A1
(en)
|
1999-09-20 |
2001-03-29 |
Takeda Chemical Industries, Ltd. |
Mch antagonists
|
|
YU23602A
(sh)
|
1999-09-30 |
2004-09-03 |
Neurogen Corporation |
Amino supstituisani pirazolo /1,5/a/-1,5-pirimidini i pirazolo /1,5-a/-1,3,5-triazini
|
|
KR20020047198A
(ko)
|
1999-09-30 |
2002-06-21 |
해피 페너 ; 해리 에이치. 페너 2세 |
특정 알킬렌 디아민-치환된피라졸로[1,5-a]-1,5-피리미딘 및피라졸로[1,5-a]-1,3,5-트리아진
|
|
OA12050A
(en)
|
1999-09-30 |
2006-05-02 |
Neurogen Corp |
Certain alkylene diamine-substituted heterocycles.
|
|
TWI262185B
(en)
|
1999-10-01 |
2006-09-21 |
Eisai Co Ltd |
Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives
|
|
ATE277044T1
(de)
|
1999-10-06 |
2004-10-15 |
Boehringer Ingelheim Pharma |
Heterocyclische verbindungen verwendbar als tyrosinkinase inhibitoren
|
|
WO2001025192A1
(en)
|
1999-10-06 |
2001-04-12 |
Melacure Therapeutics Ab |
Guanidine derivatives and their use in the production of a medicament for blocking xanthine oxidase/dehydrogenase
|
|
AP2002002481A0
(en)
|
1999-10-13 |
2002-06-30 |
Pfizer Prod Inc |
Biaryl ether derivatives useful as monoamine reuptake inhibitors.
|
|
DE19949319A1
(de)
|
1999-10-13 |
2001-06-13 |
Ruetgers Vft Ag |
Verfahren zur Herstellung von Arylalkylethern
|
|
BR0015322A
(pt)
|
1999-11-05 |
2002-07-09 |
Aventis Pharma Gmbh |
Derivados de indeno-, nafto- e benzociclohepta-dihidrotiazol, sua preparação e seu emprego como medicamentos anoréticos
|
|
IL149872A0
(en)
|
1999-12-16 |
2002-11-10 |
Schering Corp |
Substituted imidazole neuropeptide y y5 receptor antagonists
|
|
PT1249450E
(pt)
|
2000-01-17 |
2008-01-02 |
Teijin Pharma Ltd |
Derivados de benzimidazole como inibidores de quimase humana
|
|
WO2001053272A1
(en)
|
2000-01-17 |
2001-07-26 |
Teijin Limited |
Human chymase inhibitors
|
|
US6693165B2
(en)
|
2000-01-18 |
2004-02-17 |
Merck & Co., Inc. |
Cyclic peptides as potent and selective melanocortin-4 receptor antagonists
|
|
AU2001228325A1
(en)
|
2000-02-01 |
2001-08-14 |
Novo-Nordisk A/S |
Use of compounds for the regulation of food intake
|
|
AU2001234958A1
(en)
|
2000-02-11 |
2001-08-20 |
Bristol-Myers Squibb Company |
Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases
|
|
JP2001226269A
(ja)
|
2000-02-18 |
2001-08-21 |
Takeda Chem Ind Ltd |
メラニン凝集ホルモン拮抗剤
|
|
US7064142B2
(en)
|
2000-02-22 |
2006-06-20 |
Banyu Pharmaceutical, Co., Ltd. |
Imidazonline compounds
|
|
GB0004003D0
(en)
|
2000-02-22 |
2000-04-12 |
Knoll Ag |
Therapeutic agents
|
|
HRP20020688A2
(en)
|
2000-02-23 |
2004-12-31 |
Aventis Pharma Gmbh |
8,8a-dihydro-indeno[1,2-d]thiazole derivatives, substituted in position 8a, a method for their production and their use as medicaments, e.g. anorectic agents
|
|
US6531478B2
(en)
|
2000-02-24 |
2003-03-11 |
Cheryl P. Kordik |
Amino pyrazole derivatives useful for the treatment of obesity and other disorders
|
|
DE50100558D1
(de)
|
2000-02-26 |
2003-10-02 |
Aventis Pharma Gmbh |
8,8a-dihydro-indeno 1,2-d]thiazol-derivate, die in 2-stellung einen substituenten mit einer sulfonamidstruktur oder sulfonstruktur tragen; verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
|
|
FR2805810B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Compositions pharmaceutiques contenant des derives de 3- amino-azetidine, les nouveaux derives et leur preparation
|
|
FR2805818B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
|
|
FR2805817B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation
|
|
EP1132389A1
(en)
|
2000-03-06 |
2001-09-12 |
Vernalis Research Limited |
New aza-indolyl derivatives for the treatment of obesity
|
|
AU6011301A
(en)
|
2000-03-14 |
2001-09-24 |
Actelion Pharmaceuticals Ltd |
1,2,3,4-tetrahydroisoquinoline derivatives
|
|
EP1268000A4
(en)
|
2000-03-23 |
2004-12-29 |
Merck & Co Inc |
SPIROPIPERID DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS
|
|
EP1268449A4
(en)
|
2000-03-23 |
2004-09-15 |
Merck & Co Inc |
SUBSTITUTED PIPERIDINE AS MELANOCORTIN RECEPTOR AGONISTS
|
|
JP2004500401A
(ja)
|
2000-03-23 |
2004-01-08 |
ソルベイ・フアーマシユーチカルズ・ベー・ブイ |
Cb1−拮抗活性を有する4,5−ジヒドロ−1h−ピラゾール誘導体
|
|
US6600015B2
(en)
|
2000-04-04 |
2003-07-29 |
Hoffmann-La Roche Inc. |
Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity
|
|
EP1142886A1
(en)
|
2000-04-07 |
2001-10-10 |
Aventis Pharma Deutschland GmbH |
Percyquinnin, a process for its production and its use as a pharmaceutical
|
|
JP2001354671A
(ja)
|
2000-04-14 |
2001-12-25 |
Nippon Chemiphar Co Ltd |
ペルオキシソーム増殖剤応答性受容体δの活性化剤
|
|
WO2001079150A1
(en)
|
2000-04-17 |
2001-10-25 |
Novo Nordisk A/S |
New compounds, their preparation and use
|
|
ATE479429T1
(de)
|
2000-04-28 |
2010-09-15 |
Takeda Pharmaceutical |
Antagonisten des melanin-konzentrierenden hormons
|
|
GB0010757D0
(en)
|
2000-05-05 |
2000-06-28 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0011013D0
(en)
|
2000-05-09 |
2000-06-28 |
Astrazeneca Ab |
Chemical compounds
|
|
US6432960B2
(en)
|
2000-05-10 |
2002-08-13 |
Bristol-Myers Squibb Company |
Squarate derivatives of dihydropyridine NPY antagonists
|
|
AU2001263021A1
(en)
|
2000-05-10 |
2001-11-20 |
Bristol-Myers Squibb Company |
Alkylamine derivatives of dihydropyridine npy antagonists
|
|
US6444675B2
(en)
|
2000-05-10 |
2002-09-03 |
Bristol-Myers Squibb Company |
4-alkyl and 4-cycloalkyl derivatives of dihydropyridine NPY antagonists
|
|
JP2004507456A
(ja)
|
2000-05-11 |
2004-03-11 |
ブリストル−マイヤーズ スクイブ カンパニー |
成長ホルモン分泌促進薬として有用なテトラヒドロイソキノリン類縁体
|
|
JP2002371059A
(ja)
|
2000-05-16 |
2002-12-26 |
Takeda Chem Ind Ltd |
メラニン凝集ホルモン拮抗剤
|
|
CA2408913A1
(en)
|
2000-05-16 |
2001-11-22 |
Takeda Chemical Industries, Ltd. |
Melanin-concentrating hormone antagonist
|
|
EP1286697A2
(en)
|
2000-05-17 |
2003-03-05 |
Eli Lilly And Company |
Method for selectively inhibiting ghrelin action
|
|
US6391881B2
(en)
|
2000-05-19 |
2002-05-21 |
Bristol-Myers Squibb Company |
Thiourea derivatives of dihydropyridine NPY antagonists
|
|
SE0001899D0
(sv)
|
2000-05-22 |
2000-05-22 |
Pharmacia & Upjohn Ab |
New compounds
|
|
AU2001264977B2
(en)
|
2000-05-30 |
2005-04-14 |
Merck & Co., Inc. |
Melanocortin receptor agonists
|
|
AU6690001A
(en)
|
2000-06-15 |
2001-12-24 |
Schering Corp |
Thrombin receptor antagonists
|
|
AU2001272476A1
(en)
|
2000-06-16 |
2001-12-24 |
Smithkline Beecham Plc |
Piperidines for use as orexin receptor antagonists
|
|
CA2384041A1
(en)
|
2000-07-05 |
2002-01-24 |
Synaptic Pharmaceuticals Corporation |
Selective melanin concentrating hormone-1 (mch1) receptor antagonists and uses thereof
|
|
US6569861B2
(en)
|
2000-07-06 |
2003-05-27 |
Neurogen Corporation |
Melanin concentrating hormone receptor ligands
|
|
GB0019357D0
(en)
|
2000-08-07 |
2000-09-27 |
Melacure Therapeutics Ab |
Novel phenyl guanidines
|
|
AU2001283938A1
(en)
|
2000-07-24 |
2002-02-05 |
Ardana Bioscience Limited |
Ghrelin antagonists
|
|
DE60113865T2
(de)
|
2000-07-31 |
2006-07-20 |
Vernalis Research Ltd., Winnersh |
Piperazin derivate
|
|
US6768024B1
(en)
|
2000-08-04 |
2004-07-27 |
Lion Bioscience Ag |
Triamine derivative melanocortin receptor ligands and methods of using same
|
|
GB0019359D0
(en)
|
2000-08-07 |
2000-09-27 |
Melacure Therapeutics Ab |
Novel guanidines
|
|
DK1308439T3
(da)
|
2000-08-10 |
2009-01-12 |
Mitsubishi Tanabe Pharma Corp |
Prolinderivater og anvendelse af disse som lægemidler
|
|
EP1310494B1
(en)
|
2000-08-11 |
2012-01-25 |
Nippon Chemiphar Co., Ltd. |
PPAR (delta) ACTIVATORS
|
|
CA2419073A1
(en)
|
2000-08-17 |
2002-02-21 |
Gliatech, Inc. |
Novel alicyclic imidazoles as h3 agents
|
|
AU2001283573A1
(en)
|
2000-08-21 |
2002-03-04 |
Gliatech, Inc. |
The use of histamine H3 receptor inverse agonists for the control of appetite and treatment of obesity
|
|
AU2001288294A1
(en)
|
2000-08-21 |
2002-03-04 |
Merck And Co., Inc. |
Anti-hypercholesterolemic drug combination
|
|
CA2419310A1
(en)
|
2000-08-23 |
2002-02-28 |
Merck & Co., Inc. |
Substituted piperidines as melanocortin receptor agonists
|
|
US20020037829A1
(en)
|
2000-08-23 |
2002-03-28 |
Aronson Peter S. |
Use of DPPIV inhibitors as diuretic and anti-hypertensive agents
|
|
US6900226B2
(en)
|
2000-09-06 |
2005-05-31 |
Hoffman-La Roche Inc. |
Neuropeptide Y antagonists
|
|
CN1474810A
(zh)
|
2000-09-14 |
2004-02-11 |
���鹫˾ |
取代脲,神经肽yy5受体拮抗剂
|
|
WO2002026707A1
(en)
|
2000-09-26 |
2002-04-04 |
Biovitrum Ab |
Novel compounds
|
|
AU2001292480A1
(en)
|
2000-09-26 |
2002-04-08 |
Biovitrum Ab |
Novel pyridazine compounds for the treatment of diabetes
|
|
HUP0301351A3
(en)
|
2000-10-13 |
2007-05-29 |
Lilly Co Eli |
Use of substituted dipeptides as growth hormone secretagogues, process for their preparation and pharmaceutical compositions containing them
|
|
JP4047723B2
(ja)
|
2000-10-16 |
2008-02-13 |
エフ.ホフマン−ラ ロシュ アーゲー |
インドリン誘導体、および5−ht2受容体リガンドとしてのその使用
|
|
CA2423792A1
(en)
|
2000-10-20 |
2002-04-25 |
Pfizer Products Inc. |
Alpha-aryl ethanolamines and their use as beta-3 adrenergic receptor agonists
|
|
JP4734705B2
(ja)
|
2000-10-31 |
2011-07-27 |
三菱化学株式会社 |
リチウム二次電池用正極材料、リチウム二次電池用正極及びリチウム二次電池
|
|
WO2002036596A2
(en)
|
2000-11-03 |
2002-05-10 |
Wyeth |
CYCLOALKYL[b][1,4]DIAZEPINO[6,7,1-hi]INDOLES AND DERIVATIVES
|
|
ATE329901T1
(de)
|
2000-11-10 |
2006-07-15 |
Lilly Co Eli |
3-substituierte oxindolderivate als beta-3- agonisten
|
|
AU2002224038B2
(en)
|
2000-11-15 |
2006-03-09 |
Banyu Pharmaceutical Co., Ltd. |
Benzimidazole derivatives
|
|
NZ525700A
(en)
|
2000-11-20 |
2004-12-24 |
Biovitrum Ab |
Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5HT-2 receptor
|
|
CA2428905A1
(en)
|
2000-11-20 |
2002-05-23 |
Biovitrum Ab |
PIPERAZINYLPYRAZINE COMPOUNDS FOR USE AS ANTAGONISTS OF THE SEROTONIN 5-HT2 RECEPTOR
|
|
EP1353918B1
(en)
|
2000-11-28 |
2005-01-12 |
Smithkline Beecham Plc |
Morpholine derivatives as antagonists of orexin receptors
|
|
WO2002046176A1
(en)
|
2000-12-05 |
2002-06-13 |
Nippon Chemiphar Co., Ltd. |
Ppar (peroxisome proliferator activated receptor) activators
|
|
AU2002224138A1
(en)
|
2000-12-05 |
2002-06-18 |
Nippon Chemiphar Co. Ltd. |
Peroxisome proliferator activated receptor d activators
|
|
EP1347982B1
(en)
|
2000-12-12 |
2005-11-16 |
Neurogen Corporation |
Spiro isobenzofuran-1,4'-piperidin]-3-ones and 3h-spiroisobenzofuran-1,4'-piperidines
|
|
GB0030710D0
(en)
|
2000-12-15 |
2001-01-31 |
Hoffmann La Roche |
Piperazine derivatives
|
|
DE60136562D1
(de)
|
2000-12-21 |
2008-12-24 |
Schering Corp |
Heteroaryl-harnstoff-neuropeptid-y-y5-rezeptor-antagonisten
|
|
NZ525723A
(en)
|
2000-12-22 |
2004-11-26 |
Schering Corp |
1,4-di-substituted piperidine antagonists for melanin-concentrating hormone (MCH) and their use in the treatment of obesity or diabetes
|
|
WO2002051806A1
(en)
|
2000-12-22 |
2002-07-04 |
Astrazeneca Ab |
Carbazole derivatives and their use as neuropeptide y5 receptor ligands
|
|
WO2002051232A2
(en)
|
2000-12-27 |
2002-07-04 |
Actelion Pharmaceuticals Ltd. |
Novel benzazepines and related heterocyclic derivatives
|
|
EP1347979B1
(en)
|
2000-12-27 |
2007-08-08 |
F. Hoffmann-La Roche Ag |
Indole derivatives and their use as 5-ht2b and 5-ht2c receptor ligands
|
|
EP1370558B1
(en)
|
2001-01-23 |
2005-08-24 |
Eli Lilly And Company |
Piperazine- and piperidine-derivatives as melanocortin receptor agonists
|
|
JP2004524297A
(ja)
|
2001-01-23 |
2004-08-12 |
イーライ・リリー・アンド・カンパニー |
メラノコルチン受容体アゴニスト
|
|
WO2002059107A1
(en)
|
2001-01-23 |
2002-08-01 |
Eli Lilly And Company |
Substituted piperidines/piperazines as melanocortin receptor agonists
|
|
PE20021002A1
(es)
|
2001-02-02 |
2002-12-06 |
Takeda Chemical Industries Ltd |
Compuestos heterociclicos condensados
|
|
EP1363914A1
(en)
|
2001-02-05 |
2003-11-26 |
Dr. Reddy's Laboratories Ltd. |
Aryl substituted alkylcarboxylic acids as hypocholesterolemic agents
|
|
WO2002062766A2
(en)
|
2001-02-07 |
2002-08-15 |
Millennium Pharmaceuticals, Inc. |
Melanocortin-4 receptor binding compounds and methods of use thereof
|
|
US20020119958A1
(en)
|
2001-02-13 |
2002-08-29 |
Shinichiro Tojo |
Therapeutic agent for hyperlipidemia
|
|
EP1381958A4
(en)
|
2001-02-24 |
2007-05-09 |
Ibm |
GLOBAL INTERRUPT AND BARRIER NETWORKS
|
|
EP1372653B1
(en)
|
2001-02-28 |
2006-10-04 |
Merck & Co., Inc. |
Acylated piperidine derivatives as melanocortin-4 receptor agonists
|
|
EP1385506B1
(en)
|
2001-02-28 |
2009-05-06 |
Merck & Co., Inc. |
Acylated piperidine derivates as melanocortin-4 receptor agonists
|
|
GEP20053710B
(en)
|
2001-02-28 |
2005-12-26 |
Merck & Co Inc |
Acylated Piperidine Derivatives as Melanocortin-4 Receptor Agonists
|
|
GB0105772D0
(en)
|
2001-03-08 |
2001-04-25 |
Sterix Ltd |
Use
|
|
KR20030093257A
(ko)
|
2001-03-21 |
2003-12-06 |
파마코페이아, 인크. |
Mch 조정 활성을 지닌 아릴 및 바이아릴 화합물
|
|
US6900329B2
(en)
|
2001-03-21 |
2005-05-31 |
Schering Corporation |
MCH antagonists and their use in the treatment of obesity
|
|
ATE284872T1
(de)
|
2001-03-22 |
2005-01-15 |
Solvay Pharm Bv |
4,5-dihydro-1h-pyrazolderivate mit cb1- antagonistischer wirkung
|
|
EP1371650A4
(en)
|
2001-03-23 |
2005-05-04 |
Nippon Chemiphar Co |
ACTIVATED RECEPTOR ACTIVATOR BY PEROXYSOME PROLIFIERS
|
|
WO2002076454A1
(en)
|
2001-03-26 |
2002-10-03 |
Unisearch Limited |
Method for treatment of cancer and compositions for use therein
|
|
US7253178B2
(en)
|
2001-03-28 |
2007-08-07 |
Eisai Co., Ltd. |
Carboxylic acids
|
|
AU782148B2
(en)
|
2001-03-29 |
2005-07-07 |
Molecular Design International, Inc. |
Beta3-adrenoreceptor agonists, agonist compositions and methods of making and using the same
|
|
JP4549021B2
(ja)
|
2001-03-30 |
2010-09-22 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
ベンゼン化合物およびその塩
|
|
GB0108631D0
(en)
|
2001-04-05 |
2001-05-30 |
Melacure Therapeutics Ab |
Novel benzylideneamino guanidines and their uses as ligands to the melanocortin receptors
|
|
US6573287B2
(en)
|
2001-04-12 |
2003-06-03 |
Bristo-Myers Squibb Company |
2,1-oxazoline and 1,2-pyrazoline-based inhibitors of dipeptidyl peptidase IV and method
|
|
ATE460163T1
(de)
|
2001-04-12 |
2010-03-15 |
Pharmacopeia Llc |
Arly und diaryl piperidinderivate verwendbar als mch-hemmer
|
|
WO2002089800A2
(en)
|
2001-05-05 |
2002-11-14 |
Smithkline Beecham P.L.C. |
N-aroyl cyclic amine derivatives as orexin receptor antagonists
|
|
CZ20032990A3
(cs)
|
2001-05-05 |
2004-04-14 |
Smithkline Beecham P. L. C. |
N-aroylové cyklické aminy
|
|
US7030150B2
(en)
|
2001-05-11 |
2006-04-18 |
Trimeris, Inc. |
Benzimidazole compounds and antiviral uses thereof
|
|
FR2824825B1
(fr)
|
2001-05-15 |
2005-05-06 |
Servier Lab |
Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
KR100621287B1
(ko)
|
2001-05-21 |
2006-09-13 |
에프. 호프만-라 로슈 아게 |
신경 펩타이드 y 수용체에 대한 리간드로서의 퀴놀린유도체
|
|
IL158941A0
(en)
|
2001-05-22 |
2004-05-12 |
Neurogen Corp |
Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues
|
|
US6548538B2
(en)
|
2001-05-22 |
2003-04-15 |
Bayer Aktiengesellschaft |
Propionic acid derivatives
|
|
US7199147B2
(en)
|
2001-06-12 |
2007-04-03 |
Dainippon Sumitomo Pharma Co., Ltd. |
Rho kinase inhibitors
|
|
EP1406872B1
(en)
|
2001-06-20 |
2007-12-19 |
Merck & Co., Inc. |
Dipeptidyl peptidase inhibitors for the treatment of diabetes
|
|
WO2003000685A1
(fr)
|
2001-06-20 |
2003-01-03 |
Takeda Chemical Industries, Ltd. |
Derives heterocycliques a 5 chainons
|
|
DE60209348T2
(de)
|
2001-06-20 |
2006-10-12 |
Merck & Co., Inc. |
Dipeptidylpeptidase-hemmer zur behandlung von diabetes
|
|
US6825198B2
(en)
|
2001-06-21 |
2004-11-30 |
Pfizer Inc |
5-HT receptor ligands and uses thereof
|
|
GB0115517D0
(en)
|
2001-06-25 |
2001-08-15 |
Ferring Bv |
Novel antidiabetic agents
|
|
EP1405636A4
(en)
|
2001-06-26 |
2009-04-15 |
Takeda Pharmaceutical |
FUNCTIONAL REGULATOR FOR RETINOID RELATIVE RECEPTOR
|
|
SE0102299D0
(sv)
|
2001-06-26 |
2001-06-26 |
Astrazeneca Ab |
Compounds
|
|
DE10150203A1
(de)
|
2001-10-12 |
2003-04-17 |
Probiodrug Ag |
Peptidylketone als Inhibitoren der DPIV
|
|
WO2003002593A2
(en)
|
2001-06-27 |
2003-01-09 |
Probiodrug Ag |
Peptide structures useful for competitive modulation of dipeptidyl peptidase iv catalysis
|
|
WO2003002530A2
(en)
|
2001-06-27 |
2003-01-09 |
Smithkline Beecham Corporation |
Pyrrolidines as dipeptidyl peptidase inhibitors
|
|
CN1723196A
(zh)
|
2001-06-27 |
2006-01-18 |
史密丝克莱恩比彻姆公司 |
作为二肽酶抑制剂的氟代吡咯烷
|
|
ATE370943T1
(de)
|
2001-06-27 |
2007-09-15 |
Smithkline Beecham Corp |
Fluoropyrrolidine als dipeptidyl-peptidase inhibitoren
|
|
EP1404682B1
(en)
|
2001-06-29 |
2005-09-14 |
Novo Nordisk A/S |
Method of inhibiting ptp 1b and/or t-cell ptp and/or other ptpases with an asp residue at position 48
|
|
US6688713B2
(en)
|
2001-07-02 |
2004-02-10 |
Mitsubishi Digital Electronics America, Inc. |
Television base casting
|
|
EP1404675B1
(en)
|
2001-07-03 |
2008-03-12 |
Novo Nordisk A/S |
Dpp-iv-inhibiting purine derivatives for the treatment of diabetes
|
|
JP3532537B2
(ja)
|
2001-07-05 |
2004-05-31 |
株式会社テムコジャパン |
骨伝導ヘッドセット
|
|
IL159697A0
(en)
|
2001-07-05 |
2004-06-20 |
Synaptic Pharma Corp |
Substituted anilinic piperidines as mch selective antagonists
|
|
UA74912C2
(en)
|
2001-07-06 |
2006-02-15 |
Merck & Co Inc |
Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
|
|
ITMI20011483A1
(it)
|
2001-07-11 |
2003-01-11 |
Res & Innovation Soc Coop A R |
Uso di composti come antagonisti funzionali ai recettori centrali deicannabinoidi
|
|
US6960646B2
(en)
|
2001-07-12 |
2005-11-01 |
Merck & Co., Inc. |
Cyclic peptides as potent and selective melanocortin-4 receptors agonists
|
|
WO2003007990A1
(en)
|
2001-07-18 |
2003-01-30 |
Sumitomo Pharmaceuticals Company, Limited |
Myosin agonist
|
|
US7115628B2
(en)
|
2001-07-18 |
2006-10-03 |
Merck & Co., Inc. |
Bridged piperidine derivatives as melanocortin receptor agonists
|
|
WO2003007887A2
(en)
|
2001-07-20 |
2003-01-30 |
Merck & Co., Inc. |
Substituted imidazoles as cannabinoid receptor modulators
|
|
US6977264B2
(en)
|
2001-07-25 |
2005-12-20 |
Amgen Inc. |
Substituted piperidines and methods of use
|
|
US7115607B2
(en)
|
2001-07-25 |
2006-10-03 |
Amgen Inc. |
Substituted piperazinyl amides and methods of use
|
|
IL159643A0
(en)
|
2001-07-26 |
2004-06-01 |
Schering Corp |
Substituted urea neuropeptide y y5 receptor antagonists
|
|
JP4301940B2
(ja)
|
2001-07-31 |
2009-07-22 |
日清オイリオグループ株式会社 |
抗肥満剤およびその原料
|
|
WO2003014113A1
(en)
|
2001-08-06 |
2003-02-20 |
Glenmark Pharmaceuticals Limited |
Novel benzopyran compounds and process for their preparation and use
|
|
GB0119172D0
(en)
|
2001-08-06 |
2001-09-26 |
Melacure Therapeutics Ab |
Phenyl pyrrole derivatives
|
|
US7205417B2
(en)
|
2001-08-07 |
2007-04-17 |
Banyu Pharmaceutical Co., Ltd. |
Spiro compounds
|
|
CA2456964A1
(en)
|
2001-08-08 |
2003-02-20 |
Merck & Co., Inc. |
Melanin-concentrating hormone antagonists
|
|
AU2002323776B2
(en)
|
2001-08-10 |
2008-07-31 |
Nippon Chemiphar Co., Ltd. |
Activator for peroxisome proliferator-responsive receptor Delta
|
|
DE60215028T2
(de)
|
2001-08-14 |
2007-03-15 |
Eli Lilly And Co., Indianapolis |
Indol derivate als beta-3-adrenerge agonisten zur behandlung von typ 2 diabetes
|
|
WO2003016276A2
(en)
|
2001-08-14 |
2003-02-27 |
Eli Lilly And Company |
3-substituted oxindole beta-3 agonists
|
|
SE0102764D0
(sv)
|
2001-08-17 |
2001-08-17 |
Astrazeneca Ab |
Compounds
|
|
EP1452521A4
(en)
|
2001-08-17 |
2007-03-14 |
Eisai R&D Man Co Ltd |
CYCLIC COMPOUND AND AGONIST OF PPAR RECEPTOR
|
|
DE10139416A1
(de)
|
2001-08-17 |
2003-03-06 |
Aventis Pharma Gmbh |
Aminoalkyl substituierte aromatische Bicyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
US20030092041A1
(en)
|
2001-08-23 |
2003-05-15 |
Millennium Pharmaceuticals, Inc. |
Novel use for muscarinic receptor M5 in the diagnosis and treatment of metabolic disorders
|
|
KR100902799B1
(ko)
|
2001-08-24 |
2009-06-12 |
데이진 가부시키가이샤 |
키마제 저해제 및 ace 저해제를 유효성분으로 함유하는약제
|
|
AU2002331766A1
(en)
|
2001-08-31 |
2003-03-18 |
University Of Connecticut |
Novel pyrazole analogs acting on cannabinoid receptors
|
|
GB0121941D0
(en)
|
2001-09-11 |
2001-10-31 |
Astrazeneca Ab |
Chemical compounds
|
|
US6915444B2
(en)
|
2001-09-12 |
2005-07-05 |
Rockwell Automation Technologies, Inc. |
Network independent safety protocol for industrial controller using data manipulation techniques
|
|
EP1426370A4
(en)
|
2001-09-13 |
2009-12-23 |
Nisshin Pharma Inc |
PROPANOLAMINE DERIVATIVE WITH 1,4-BENZODIOXANRING
|
|
MXPA04001785A
(es)
|
2001-09-14 |
2004-07-08 |
Bayer Ag |
Benzofurano y derivados de dihidrobenzofurano utiles como agonistas de beta-3 adrenoreceptores.
|
|
US6869975B2
(en)
|
2001-09-14 |
2005-03-22 |
Tularik Inc. |
Linked biaryl compounds
|
|
EP1426366A4
(en)
|
2001-09-14 |
2004-12-08 |
Mitsubishi Pharma Corp |
THIAZOLIDE DERIVATIVES AND THEIR MEDICAL USE
|
|
ATE450508T1
(de)
|
2001-09-14 |
2009-12-15 |
High Point Pharmaceuticals Llc |
Substituierte piperidinen mit selektiver bindungsfähigkeit zu histamin h3-rezeptoren
|
|
EP1430027B1
(en)
|
2001-09-14 |
2010-09-01 |
High Point Pharmaceuticals, LLC |
Novel aminoazetidine, -pyrrolidine and -piperidine derivatives
|
|
FR2829765A1
(fr)
*
|
2001-09-14 |
2003-03-21 |
Lipha |
Derives imidazolylalkoxylarylalcanoiques leurs applications en therapeutique
|
|
EP1463727A2
(en)
|
2001-09-19 |
2004-10-06 |
Novo Nordisk A/S |
Heterocyclic compounds that are inhibitors of the enzyme dpp-iv
|
|
WO2003024447A1
(en)
|
2001-09-20 |
2003-03-27 |
Smithkline Beecham Corporation |
Inhibitors of glycogen synthase kinase-3
|
|
TWI231757B
(en)
|
2001-09-21 |
2005-05-01 |
Solvay Pharm Bv |
1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
|
|
ES2272809T3
(es)
|
2001-09-21 |
2007-05-01 |
Solvay Pharm Bv |
Nuevos derivados de 4,5-dihidro-1h-pirazol con actividad antagonista de cb1.
|
|
US6974810B2
(en)
|
2001-09-21 |
2005-12-13 |
Solvay Pharmaceuticals B.V. |
4,5-Dihydro-1H-pyrazole derivatives having potent CB1-antagonistic activity
|
|
US6509367B1
(en)
|
2001-09-22 |
2003-01-21 |
Virginia Commonwealth University |
Pyrazole cannabinoid agonist and antagonists
|
|
GT200200188A
(es)
|
2001-09-24 |
2003-06-25 |
|
Preparacion y uso de derivados de imidazol para el tratamiento de la obesidad
|
|
WO2003027114A1
(en)
|
2001-09-24 |
2003-04-03 |
Bayer Pharmaceuticals Corporation |
Preparation and use of 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives for treatment of obesity
|
|
WO2003026576A2
(en)
|
2001-09-24 |
2003-04-03 |
Board Of Supervisors Of Louisiana State Universityand Agricultural And Mechanical College |
Induction of brown adipocytes by transcription factor nfe2l2
|
|
PL205971B1
(pl)
|
2001-09-24 |
2010-06-30 |
Imp Innovations Ltd |
Zastosowanie PYY₃-₃₆ do wytwarzania leku na ograniczanie apetytu, zmniejszenie otyłości lub do zapobiegania otyłości
|
|
MXPA04002438A
(es)
|
2001-09-24 |
2004-06-29 |
Bayer Pharmaceuticals Corp |
Preparacion y uso de derivados de pirroll para el tratamiento de la obesidad.
|
|
RU2004112787A
(ru)
|
2001-09-26 |
2005-10-10 |
Байер Фармасьютикалс Корпорейшн (US) |
Производные 1,6-нафтиридина как противодиабетические средства
|
|
US6787558B2
(en)
|
2001-09-28 |
2004-09-07 |
Hoffmann-La Roche Inc. |
Quinoline derivatives
|
|
AU2002334733B2
(en)
|
2001-10-01 |
2006-11-23 |
Arena Pharmaceuticals, Inc. |
MCH receptors antagonists
|
|
US7119110B2
(en)
|
2001-10-05 |
2006-10-10 |
Interhealth Nutraceuticals Incorporated |
Method and composition for preventing or reducing the symptoms of insulin resistance syndrome
|
|
WO2003031408A2
(en)
|
2001-10-08 |
2003-04-17 |
Eli Lilly And Company |
Tricyclic compounds useful for modulating lxr
|
|
EP1465867A1
(en)
|
2001-10-09 |
2004-10-13 |
Neurocrine Biosciences, Inc. |
Ligands of melanocortin receptors and compositions and methods related thereto
|
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
GB0124463D0
(en)
|
2001-10-11 |
2001-12-05 |
Smithkline Beecham Plc |
Compounds
|
|
JP4276074B2
(ja)
|
2001-10-12 |
2009-06-10 |
日本ケミファ株式会社 |
ペルオキシソーム増殖剤応答性受容体δの活性化剤
|
|
US20050014805A1
(en)
|
2001-10-12 |
2005-01-20 |
Chenzhi Zhang |
Phenyl substituted 5-membered nitrogen containing heterocycles for the treatment of obesity
|
|
US6573396B2
(en)
|
2001-10-12 |
2003-06-03 |
Exxonmobil Chemical Patents Inc. |
Co-production of dialkyl carbonates and diols with treatment of hydroxy alkyl carbonate
|
|
GB0124627D0
(en)
|
2001-10-15 |
2001-12-05 |
Smithkline Beecham Plc |
Novel compounds
|
|
IL161431A0
(en)
|
2001-10-16 |
2004-09-27 |
Reddys Lab Ltd Dr |
beta-PHENYL-alpha-OXYSUBSTITUTED PROPIONIC ACID DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
|
|
KR20050036876A
(ko)
|
2001-10-17 |
2005-04-20 |
노보 노르디스크 에이/에스 |
디카르복실산 유도체, 그것의 제제 및 치료에의 사용
|
|
DE10151390A1
(de)
|
2001-10-18 |
2003-05-08 |
Bayer Ag |
Essigsäurederivate
|
|
CN1585751A
(zh)
|
2001-10-25 |
2005-02-23 |
武田药品工业株式会社 |
喹啉化合物
|
|
US6861440B2
(en)
|
2001-10-26 |
2005-03-01 |
Hoffmann-La Roche Inc. |
DPP IV inhibitors
|
|
EP1452526A1
(en)
|
2001-10-29 |
2004-09-01 |
Japan Tobacco Inc. |
Indole compound and medicinal use thereof
|
|
US7342117B2
(en)
|
2001-10-30 |
2008-03-11 |
Astellas Pharma Inc. |
α-form or β-form crystal of acetanilide derivative
|
|
GB0126292D0
(en)
|
2001-11-01 |
2002-01-02 |
Smithkline Beecham Plc |
Compounds
|
|
MXPA04004178A
(es)
|
2001-11-01 |
2004-09-06 |
Janssen Pharmaceutica Nv |
Heteroarilaminas como inhibidores de glucogeno cintasa cinasa 3beta.
|
|
CN1582277A
(zh)
|
2001-11-01 |
2005-02-16 |
詹森药业有限公司 |
用作糖原合酶激酶3β抑制剂的酰胺衍生物
|
|
HN2002000317A
(es)
|
2001-11-02 |
2003-05-21 |
Pfizer |
Inhibidores de pde9 para tratamiento de trastornos cardiovasculares
|
|
JP2005508978A
(ja)
|
2001-11-02 |
2005-04-07 |
ファイザー・プロダクツ・インク |
Pde9阻害薬によるインスリン抵抗性症候群及び2型糖尿病の治療
|
|
EP1442028A4
(en)
|
2001-11-06 |
2009-11-04 |
Bristol Myers Squibb Co |
SUBSTITUTED ACID DERIVATIVES, WHICH APPRECIATE AS ANTIDIBILICS AND AGENTS AGAINST OBESITAS, AND METHODS
|
|
US7163952B2
(en)
|
2001-12-03 |
2007-01-16 |
Japan Tobacco Inc. |
Azole compound and medicinal use thereof
|
|
WO2003055482A1
(en)
|
2001-12-21 |
2003-07-10 |
Novo Nordisk A/S |
Amide derivatives as gk activators
|
|
AU2002360732A1
(en)
|
2001-12-26 |
2003-07-24 |
Guilford Pharmaceuticals |
Change inhibitors of dipeptidyl peptidase iv
|
|
US6727261B2
(en)
|
2001-12-27 |
2004-04-27 |
Hoffman-La Roche Inc. |
Pyrido[2,1-A]Isoquinoline derivatives
|
|
KR100974901B1
(ko)
|
2001-12-28 |
2010-08-10 |
아카디아 파마슈티칼스 인코포레이티드 |
모노아민 수용체 조정자로서의 스피로아자사이클릭 화합물
|
|
US20050113283A1
(en)
|
2002-01-18 |
2005-05-26 |
David Solow-Cordero |
Methods of treating conditions associated with an EDG-4 receptor
|
|
JP2005519915A
(ja)
|
2002-01-18 |
2005-07-07 |
セレテック・リミテッド・ライアビリティ・カンパニー |
Edg受容体に関連する症状の処置方法
|
|
AU2003208952B2
(en)
|
2002-01-30 |
2008-04-24 |
Amgen Inc. |
Heterocyclic arylsulfonamidobenzylic compounds
|
|
BR0307409A
(pt)
|
2002-02-01 |
2004-12-28 |
Dainippon Pharmaceutical Co |
Compostos de hidrazida de ácido 2-furanocarboxìlico, composições farmacêuticas contendo os mesmos e uso dos mesmos para preparação de um agente preventivo ou terapêutico
|
|
JP2005529077A
(ja)
|
2002-02-25 |
2005-09-29 |
イーライ・リリー・アンド・カンパニー |
ペルオキシソーム増殖因子活性化受容体調節物質
|
|
CN1630629B
(zh)
|
2002-02-28 |
2010-05-05 |
日本烟草产业株式会社 |
酯化合物及其医药用途
|
|
ATE486842T1
(de)
|
2002-03-12 |
2010-11-15 |
Merck Sharp & Dohme |
Substituierte amide
|
|
WO2003080564A1
(en)
*
|
2002-03-20 |
2003-10-02 |
Schering Aktiengesellschaft |
Menthol substituted antithrombotic pai-1 inhibitors
|
|
JPWO2003091216A1
(ja)
|
2002-04-25 |
2005-09-02 |
住友製薬株式会社 |
新規ピペリジン誘導体
|
|
JPWO2003091213A1
(ja)
|
2002-04-25 |
2005-09-02 |
アステラス製薬株式会社 |
新規なアミド誘導体又はその塩
|
|
JP2005534632A
(ja)
|
2002-05-10 |
2005-11-17 |
ニューロクライン バイオサイエンセズ, インコーポレイテッド |
メラノコルチンレセプターリガンドとしての置換ピペラジン
|
|
DE10222034A1
(de)
|
2002-05-17 |
2003-11-27 |
Bayer Ag |
Tetrahydroisochinolin-Derivate
|
|
US20060148858A1
(en)
|
2002-05-24 |
2006-07-06 |
Tsuyoshi Maekawa |
1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity
|
|
CN100348609C
(zh)
|
2002-06-19 |
2007-11-14 |
卡罗生物股份公司 |
治疗代谢紊乱的糖皮质激素受体配基
|
|
DE10229777A1
(de)
|
2002-07-03 |
2004-01-29 |
Bayer Ag |
Indolin-Phenylsulfonamid-Derivate
|
|
GB0215579D0
(en)
|
2002-07-05 |
2002-08-14 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2004004611A1
(en)
|
2002-07-08 |
2004-01-15 |
Coloplast A/S |
Conduit device
|
|
SE0202134D0
(sv)
|
2002-07-08 |
2002-07-08 |
Astrazeneca Ab |
Therapeutic agents
|
|
MXPA04002269A
(es)
|
2002-07-09 |
2004-06-29 |
Actelion Pharmaceuticals Ltd |
Derivados de 7,8,9,10-tetrahidro-6h-azepino,6,7,8,9-tetrahidro-pirido y 2,3-dihidro-2h-pirrolo[2,1-b]-quinazolinona.
|
|
JPWO2004007439A1
(ja)
|
2002-07-10 |
2005-11-10 |
住友製薬株式会社 |
ビアリール誘導体
|
|
WO2004009806A1
(de)
|
2002-07-18 |
2004-01-29 |
Basf Aktiengesellschaft |
Nadh-abhängige cytochrom b5 reduktase als target für herbizide
|
|
DE10233817A1
(de)
|
2002-07-25 |
2004-02-12 |
Aventis Pharma Deutschland Gmbh |
Substituierte Diarylheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
JP2005533858A
(ja)
|
2002-07-27 |
2005-11-10 |
アストラゼネカ アクチボラグ |
化合物
|
|
MXPA05000962A
(es)
|
2002-07-29 |
2005-05-16 |
Hoffmann La Roche |
Nuevos benzodioxoles.
|
|
JP2004067629A
(ja)
|
2002-08-09 |
2004-03-04 |
Yamanouchi Pharmaceut Co Ltd |
ミトコンドリア機能活性化剤及び新規なベンゾイミダゾール誘導体
|
|
DE10238860A1
(de)
|
2002-08-24 |
2004-03-04 |
Bayerische Motoren Werke Ag |
Brennstoff-Zelle mit einer das Brenngas über der Elektroden-Oberfläche verteilenden perforierten Folie
|
|
US6849761B2
(en)
|
2002-09-05 |
2005-02-01 |
Wyeth |
Substituted naphthoic acid derivatives useful in the treatment of insulin resistance and hyperglycemia
|
|
US7553867B2
(en)
|
2002-09-06 |
2009-06-30 |
Takeda Pharmaceutical Company Limited |
Furan or thiophene derivative and medicinal use thereof
|
|
JP2006501820A
(ja)
|
2002-09-06 |
2006-01-19 |
バイエル・フアーマシユーチカルズ・コーポレーシヨン |
修飾glp−1受容体アゴニストおよびそれらの薬理学的使用法
|
|
WO2004026866A1
(en)
|
2002-09-18 |
2004-04-01 |
Glaxo Group Limited |
N-aroyl cyclic amines as orexin receptor antagonists
|
|
AU2003275195A1
(en)
|
2002-09-18 |
2004-04-08 |
Hartmut M. Hanauske-Abel |
INHIBITORS OF 11Beta-HYDROXYSTEROID DEHYDROGENASE AND USES THEREFOR
|
|
US7045527B2
(en)
|
2002-09-24 |
2006-05-16 |
Amgen Inc. |
Piperidine derivatives
|
|
WO2004028453A2
(en)
|
2002-09-25 |
2004-04-08 |
Neurogen Corporation |
Methods for preventing and treating obesity in patients with mc4 receptor mutations
|
|
MXPA05003559A
(es)
|
2002-10-03 |
2005-06-03 |
Novartis Ag |
(tiazol-2-il)-amida o sulfonamida substituida como activadores de glicocinasa utiles en el tratamiento de diabetes de tipo 2.
|
|
KR20050051691A
(ko)
|
2002-10-11 |
2005-06-01 |
아스트라제네카 아베 |
1,4-이치환 피페리딘 유도체 및 11-베타hsd1억제제로서의 이들의 용도
|
|
CN1689322A
(zh)
|
2002-10-11 |
2005-10-26 |
皇家飞利浦电子股份有限公司 |
图像转换单元和方法
|
|
KR20050049525A
(ko)
|
2002-10-11 |
2005-05-25 |
가부시키가이샤산와카가쿠켄큐쇼 |
Glp-1 유도체 및 그의 경점막 흡수형 제제
|
|
CA2502356A1
(en)
|
2002-10-15 |
2004-04-29 |
Synta Pharmaceuticals Corp. |
Aromatic bicyclic heterocyles to modulate 1l - 12 production
|
|
PL376301A1
(en)
|
2002-10-24 |
2005-12-27 |
Sterix Limited |
Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 and type 2
|
|
US6852748B1
(en)
|
2002-10-30 |
2005-02-08 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl]-pyrrolidine-2-carboxylic acid amide
|
|
AU2003286776A1
(en)
|
2002-10-30 |
2004-06-07 |
Guilford Pharmaceuticals Inc. |
Novel inhibitors of dipeptidyl peptidase iv
|
|
DE10250743A1
(de)
|
2002-10-31 |
2004-05-19 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Amid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
|
|
FR2846656B1
(fr)
|
2002-11-05 |
2004-12-24 |
Servier Lab |
Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
GB0225944D0
(en)
|
2002-11-06 |
2002-12-11 |
Glaxo Group Ltd |
Novel compounds
|
|
EP1562574A1
(en)
|
2002-11-07 |
2005-08-17 |
Astrazeneca AB |
2-oxo-ethanesulfonamide derivates
|
|
GB0225986D0
(en)
|
2002-11-07 |
2002-12-11 |
Astrazeneca Ab |
Chemical compounds
|
|
EP1559422B1
(en)
|
2002-11-08 |
2014-04-30 |
Takeda Pharmaceutical Company Limited |
Receptor function controlling agent
|
|
DE10251927A1
(de)
|
2002-11-08 |
2004-05-19 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
WO2004043913A2
(en)
|
2002-11-08 |
2004-05-27 |
Trimeris, Inc. |
Hetero-substituted benzimidazole compounds and antiviral uses thereof
|
|
US20050143449A1
(en)
|
2002-11-15 |
2005-06-30 |
The Salk Institute For Biological Studies |
Non-steroidal farnesoid X receptor modulators and methods for the use thereof
|
|
AU2003274601A1
(en)
|
2002-11-18 |
2004-06-15 |
Pfizer Products Inc. |
Dipeptidyl peptidase iv inhibiting fluorinated cyclic amides
|
|
GB0226931D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0226930D0
(en)
|
2002-11-19 |
2002-12-24 |
Astrazeneca Ab |
Chemical compounds
|
|
AU2003281978A1
(en)
|
2002-11-22 |
2004-06-18 |
Boehringer Ingelheim International Gmbh |
2,5-diketopiperazines for the treatment of obesity
|
|
CA2504856A1
(en)
|
2002-11-25 |
2004-06-10 |
Gni Usa |
Inferring gene regulatory networks from time-ordered gene expression data using differential equations
|
|
GB0227813D0
(en)
|
2002-11-29 |
2003-01-08 |
Astrazeneca Ab |
Chemical compounds
|
|
UY28103A1
(es)
|
2002-12-03 |
2004-06-30 |
Boehringer Ingelheim Pharma |
Nuevas imidazo-piridinonas sustituidas, su preparación y su empleo como medicacmentos
|
|
WO2004050610A2
(en)
|
2002-12-04 |
2004-06-17 |
Gene Logic Inc. |
Modulators of melanocortin receptor
|
|
AU2003302925A1
(en)
|
2002-12-11 |
2004-06-30 |
Eli Lilly And Company |
Novel mch receptor antagonists
|
|
JP2004196702A
(ja)
|
2002-12-18 |
2004-07-15 |
Yamanouchi Pharmaceut Co Ltd |
新規なアミド誘導体又はその塩
|
|
WO2004056744A1
(en)
|
2002-12-23 |
2004-07-08 |
Janssen Pharmaceutica N.V. |
Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
|
|
US20040209928A1
(en)
|
2002-12-30 |
2004-10-21 |
Ravi Kurukulasuriya |
Glucagon receptor antagonists/inverse agonists
|
|
WO2004063179A1
(en)
|
2003-01-06 |
2004-07-29 |
Eli Lilly And Company |
Substituted arylcyclopropylacetamides as glucokinase activators
|
|
WO2004063194A1
(en)
|
2003-01-06 |
2004-07-29 |
Eli Lilly And Company |
Heteroaryl compounds
|
|
DE10301788B4
(de)
|
2003-01-20 |
2005-08-25 |
Aventis Pharma Deutschland Gmbh |
Pharmazeutische Verwendung von Pyrimido[5,4-e][1,2,4]triazin-5,7-dionen
|
|
TW200503994A
(en)
|
2003-01-24 |
2005-02-01 |
Novartis Ag |
Organic compounds
|
|
WO2004067509A1
(ja)
|
2003-01-31 |
2004-08-12 |
Sanwa Kagaku Kenkyusho Co., Ltd. |
ジペプチジルペプチダーゼivを阻害する化合物
|
|
US6759546B1
(en)
|
2003-02-04 |
2004-07-06 |
Allergan, Inc. |
3,5-di-iso-propyl-heptatrienoic acid derivatives having serum glucose reducing activity
|
|
JP2006518738A
(ja)
|
2003-02-12 |
2006-08-17 |
トランス テック ファーマ,インコーポレイテッド |
治療薬としての置換アゾール誘導体
|
|
WO2004072041A1
(en)
|
2003-02-12 |
2004-08-26 |
Care X S.A. |
Tetrahydroquinolines as agonists of liver- x receptors
|
|
WO2004071454A2
(en)
|
2003-02-13 |
2004-08-26 |
Guilford Pharmaceuticals Inc. |
Substituted azetidine compounds as inhibitors of dipeptidyl peptidase iv
|
|
US20050154011A1
(en)
|
2003-02-20 |
2005-07-14 |
The Procter & Gamble Company |
Tetrahydroisoquinolnyl sulfamic acids
|
|
FR2851563B1
(fr)
|
2003-02-26 |
2005-04-22 |
Sod Conseils Rech Applic |
Nouveaux derives de benzimidazole et d'imidazo-pyridine et leur utilisation en tant que medicament
|
|
US20040224992A1
(en)
|
2003-02-27 |
2004-11-11 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
EP1460069A1
(en)
|
2003-03-20 |
2004-09-22 |
MyoContract Ltd. |
Substituted cyclohexyl and piperidinyl derivatives as melanocortin-4 receptor modulators
|
|
EP1468999A1
(en)
|
2003-03-20 |
2004-10-20 |
MyoContract Ltd. |
Substituted piperidine and piperazine derivatives as melanocortin-4 receptor modulators
|
|
CL2004000553A1
(es)
|
2003-03-20 |
2005-02-04 |
Actelion Pharmaceuticals Ltd |
Uso de compuestos derivados de guanidina como antagonistas del receptor de neuropeptido ff; compuestos derivados de guanidina; procedimientos de preparacion; y composicion farmaceutica que los comprende.
|
|
US7531553B2
(en)
|
2003-03-21 |
2009-05-12 |
Amgen Inc. |
Heterocyclic compounds and methods of use
|
|
AU2004224156B2
(en)
|
2003-03-26 |
2010-08-12 |
Actelion Pharmaceuticals Ltd. |
Tetrahydroisoquinolyl acetamide derivatives for use as orexin receptor antagonists
|
|
JP2004315511A
(ja)
|
2003-03-31 |
2004-11-11 |
Taisho Pharmaceut Co Ltd |
Mch受容体アンタゴニスト
|
|
FR2852957B1
(fr)
|
2003-03-31 |
2005-06-10 |
Sod Conseils Rech Applic |
Nouveaux derives d'imidazo-pyridine et leur utilisation en tant que medicament
|
|
WO2004087680A1
(en)
|
2003-03-31 |
2004-10-14 |
Taisho Pharmaceutical Co., Ltd. |
Novel quinazoline derivatives and methods of treatment related to the use thereof
|
|
US20040199842A1
(en)
|
2003-04-04 |
2004-10-07 |
Sartschev Ronald A. |
Test system with high accuracy time measurement system
|
|
WO2004089279A2
(en)
|
2003-04-08 |
2004-10-21 |
Yeda Research And Development Co. Ltd. |
Long-acting derivatives of pyy agonists
|
|
JP3819415B2
(ja)
|
2003-04-09 |
2006-09-06 |
日本たばこ産業株式会社 |
複素芳香5員環化合物及びその医薬用途
|
|
GB0308335D0
(en)
|
2003-04-10 |
2003-05-14 |
Novartis Ag |
Organic compounds
|
|
EP1615667A2
(en)
|
2003-04-11 |
2006-01-18 |
Novo Nordisk A/S |
Combinations of an 11-beta-hydroxysteroid dehydrogenase type 1 inhibitor and a glucocorticoid receptor agonist
|
|
WO2004092146A2
(en)
|
2003-04-14 |
2004-10-28 |
The Institutes For Pharmaceutical Discovery, Llc |
N- (((((1,3-thiazol-2-yl) amino) carbonyl) phenyl) sulfonyl) phenylalanine derivatives and related compounds for the treatment of diabetes
|
|
EP1620427A1
(en)
|
2003-04-17 |
2006-02-01 |
Pfizer Products Inc. |
Carboxamide derivatives as anti-diabetic agents
|
|
EP1633709A1
(en)
|
2003-04-30 |
2006-03-15 |
Pfizer Products Inc. |
Anti-diabetic agents
|
|
DE602004024880D1
(de)
|
2003-05-01 |
2010-02-11 |
Vernalis Res Ltd |
Azetidincarboxamid-derivate zur verwendung zur behandlung von cb1-rezeptor-vermittelten krankheiten
|
|
AU2003902260A0
(en)
|
2003-05-09 |
2003-05-29 |
Fujisawa Pharmaceutical Co., Ltd. |
Dpp-iv inhibitor
|
|
US7119205B2
(en)
|
2003-05-16 |
2006-10-10 |
Abbott Laboratories |
Thienopyridones as AMPK activators for the treatment of diabetes and obesity
|
|
WO2004108674A1
(ja)
|
2003-06-05 |
2004-12-16 |
Kissei Pharmaceutical Co., Ltd. |
アミノアルコール誘導体、それを含有する医薬組成物およびそれらの用途
|
|
AU2003902828A0
(en)
|
2003-06-05 |
2003-06-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Dpp-iv inhibitor
|
|
AU2004252109B2
(en)
|
2003-06-11 |
2010-04-08 |
Merck Sharp & Dohme Corp. |
Substituted 3-alkyl and 3-alkenyl azetidine derivatives
|
|
JP2006527212A
(ja)
|
2003-06-12 |
2006-11-30 |
ノボ ノルディスク アクティーゼルスカブ |
ホルモン感受性リパーゼの阻害剤として使用するための、置換ピペラジンカルバメート
|
|
JP2006527770A
(ja)
|
2003-06-18 |
2006-12-07 |
アストラゼネカ アクチボラグ |
Cb1モジュレーターとしての2−置換5,6−ジアリール−ピラジン誘導体
|
|
GB0314057D0
(en)
|
2003-06-18 |
2003-07-23 |
Astrazeneca Ab |
Therapeutic agents
|
|
GB0314049D0
(en)
|
2003-06-18 |
2003-07-23 |
Astrazeneca Ab |
Therapeutic agents
|
|
GB0314261D0
(en)
|
2003-06-19 |
2003-07-23 |
Astrazeneca Ab |
Therapeutic agents
|
|
AU2004251616A1
(en)
|
2003-06-19 |
2005-01-06 |
Eli Lilly And Company |
Melanocortin receptor 4(MC4) agonists and their uses
|
|
CA2528785A1
(en)
|
2003-06-20 |
2005-01-06 |
Matthias Heinrich Nettekoven |
2-amidobenzothiazoles as cb1 receptor inverse agonists
|
|
US7355049B2
(en)
|
2003-06-24 |
2008-04-08 |
Hoffmann-La Roche Inc. |
Biaryloxymethylarenecarboxylic acids as glycogen synthase activator
|
|
GB0314967D0
(en)
|
2003-06-26 |
2003-07-30 |
Hoffmann La Roche |
Piperazine derivatives
|
|
CA2530111A1
(en)
|
2003-06-27 |
2005-01-06 |
Tel-Aviv University Future Technology Development L.P. |
Glycogen synthase kinase-3 inhibitors
|
|
CN1816530A
(zh)
|
2003-07-01 |
2006-08-09 |
麦克公司 |
用于治疗高眼压症的眼用组合物
|
|
KR20060037391A
(ko)
|
2003-07-21 |
2006-05-03 |
스미스클라인 비참 코포레이션 |
(2S,4S)-4-플루오로-1-[4-플루오로-베타-(4-플루오로페닐)-L-페닐알라닐]-2-피롤리딘카르보니트릴 p-톨루엔설폰산염 및 이의 무수 결정 형태
|
|
JP2005042839A
(ja)
|
2003-07-23 |
2005-02-17 |
Iseki & Co Ltd |
作業車両の変速制御装置
|
|
AU2004259012C1
(en)
|
2003-07-23 |
2012-08-02 |
Exelixis, Inc. |
Anaplastic lymphoma kinase modulators and methods of use
|
|
US7008953B2
(en)
|
2003-07-30 |
2006-03-07 |
Agouron Pharmaceuticals, Inc. |
3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
|
|
DE602004030344D1
(de)
|
2003-07-31 |
2011-01-13 |
Tranzyme Pharma Inc |
Räumlich definierte makrocyclische verbindungen, die sich für die entdeckung von arzneimittel eignen
|
|
GB0318464D0
(en)
|
2003-08-07 |
2003-09-10 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0318463D0
(en)
|
2003-08-07 |
2003-09-10 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2005020892A2
(en)
|
2003-08-08 |
2005-03-10 |
Mitochroma Research, Inc. |
Pharmaceutical compositions and methods for metabolic modulation
|
|
RU2006107444A
(ru)
|
2003-08-12 |
2007-09-20 |
Ф.Хоффманн-Ля Рош Аг (Ch) |
2-амино-5-бензоилтиазолы в качестве антагонистов npy
|
|
US7326706B2
(en)
|
2003-08-15 |
2008-02-05 |
Bristol-Myers Squibb Company |
Pyrazine modulators of cannabinoid receptors
|
|
US20050148643A1
(en)
|
2003-08-19 |
2005-07-07 |
Agouron Pharmaceuticals, Inc. |
Carbamate compositions and methods fo rmodulating the activity of the CHK1 enzyme
|
|
WO2005019168A2
(en)
|
2003-08-20 |
2005-03-03 |
Pfizer Products Inc. |
Fluorinated lysine derivatives as dipeptidyl peptidase iv inhibitors
|
|
AU2004266536A1
(en)
|
2003-08-22 |
2005-03-03 |
Teijin Pharma Limited |
Drug containing chymase inhibitor as the active ingredient
|
|
TWI290140B
(en)
|
2003-08-25 |
2007-11-21 |
Schering Corp |
2-Substituted benzimidazole derivatives as selective melanin concentrating hormone receptor antagonists for thr treatment of obesity and related disorders
|
|
WO2005019218A1
(ja)
|
2003-08-26 |
2005-03-03 |
Teijin Pharma Limited |
ピロロピリミジンチオン誘導体
|
|
WO2005023762A1
(en)
|
2003-09-04 |
2005-03-17 |
Abbott Laboratories |
Pyrrolidine-2-carbonitrile derivatives and their use as inhibitors of dipeptidyl peptidase-iv (dpp-iv)
|
|
WO2005028624A2
(en)
|
2003-09-15 |
2005-03-31 |
Plexxikon, Inc. |
Molecular scaffolds for kinase ligand development
|
|
ES2326980T3
(es)
*
|
2003-10-02 |
2009-10-22 |
Schering Corporation |
Aminobenzimidazoles utiles como antagonistas selectivos del receptor de la hormona concentrada de melamina (mch) para el tratamiento de la obesidad y desordenes asociados.
|
|
US20050107374A1
(en)
|
2003-10-21 |
2005-05-19 |
Amgen Inc. |
Substituted heterocyclic compounds and methods of use
|
|
CA2543707A1
(en)
|
2003-10-31 |
2005-05-19 |
Takeda Pharmaceutical Company Limited |
Nitrogen-containing fused heterocyclic compounds
|
|
DK1692113T3
(en)
|
2003-11-14 |
2018-01-08 |
Lorus Therapeutics Inc |
ARYLIMIDAZOLES AND USE THEREOF AS ANTICANCES
|
|
EP1689383B1
(en)
|
2003-11-19 |
2012-10-31 |
Metabasis Therapeutics, Inc. |
Novel phosphorus-containing thyromimetics
|
|
TW200522944A
(en)
|
2003-12-23 |
2005-07-16 |
Lilly Co Eli |
CB1 modulator compounds
|
|
US20050187277A1
(en)
|
2004-02-12 |
2005-08-25 |
Mjalli Adnan M. |
Substituted azole derivatives, compositions, and methods of use
|
|
UA83416C2
(en)
|
2004-02-13 |
2008-07-10 |
Баниу Фармасьютикал Ко., Лтд. |
Fused ring 4-oxopyrimidine derivative
|
|
US7393847B2
(en)
*
|
2004-03-13 |
2008-07-01 |
Boehringer Ingleheim International Gmbh |
Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions
|
|
US7737295B2
(en)
|
2004-04-13 |
2010-06-15 |
Merck Sharp & Dohme Corp. |
CETP inhibitors
|
|
US7097961B2
(en)
|
2004-05-17 |
2006-08-29 |
Agfa Gevaert |
Stabilizers for use in substantially light-insensitive thermographic recording materials
|
|
JP2008501714A
(ja)
|
2004-06-04 |
2008-01-24 |
武田薬品工業株式会社 |
ジペプチジルペプチダーゼインヒビター
|
|
WO2005121132A1
(ja)
|
2004-06-11 |
2005-12-22 |
Shionogi & Co., Ltd. |
抗hcv作用を有する縮合ヘテロ環化合物
|
|
DE102004028862A1
(de)
*
|
2004-06-15 |
2005-12-29 |
Merck Patent Gmbh |
3-Aminoindazole
|
|
DOP2005000123A
(es)
|
2004-07-02 |
2011-07-15 |
Merck Sharp & Dohme |
Inhibidores de cetp
|
|
US7732479B2
(en)
|
2004-08-19 |
2010-06-08 |
Tel Aviv University Future Technology Development L.P. |
Compositions for treating amyloid associated diseases
|
|
GB0420719D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
CA2583326A1
(en)
*
|
2004-10-08 |
2006-04-13 |
Takeda Pharmaceutical Company Limited |
Receptor function regulating agent
|
|
BRPI0517930A
(pt)
|
2004-11-02 |
2008-10-21 |
Dsm Ip Assets Bv |
aditivo para preparações de protetor solar contra uv
|
|
WO2006053342A2
(en)
|
2004-11-12 |
2006-05-18 |
Osi Pharmaceuticals, Inc. |
Integrin antagonists useful as anticancer agents
|
|
JP2008522984A
(ja)
|
2004-12-06 |
2008-07-03 |
ニューサウス イノベイションズ ピーティーワイ リミテッド |
癌の処置
|
|
WO2006078907A1
(en)
|
2005-01-20 |
2006-07-27 |
Amgen Inc. |
2-substituted benzimidazole derivatives as vanilloid receptor ligands and their use in treatments
|
|
WO2006094209A2
(en)
|
2005-03-03 |
2006-09-08 |
Sirtris Pharmaceuticals, Inc. |
N-benzimidazolylalkyl-substituted amide sirtuin modulators
|
|
MX2007011234A
(es)
|
2005-03-14 |
2007-11-12 |
Transtech Pharma Inc |
Derivados de benzazol, composiciones y metodos de uso en la forma de inhibidores de b-secretasa.
|
|
TWI370820B
(en)
|
2005-04-27 |
2012-08-21 |
Takeda Pharmaceutical |
Fused heterocyclic compounds
|
|
CA2609394A1
(en)
|
2005-05-23 |
2006-11-30 |
Masaki Takagi |
Pyrazole compound and therapeutic agent for diabetes comprising the same
|
|
EP1888574B1
(en)
|
2005-05-25 |
2009-09-02 |
Actelion Pharmaceuticals Ltd. |
New antibiotic derivatives
|
|
BRPI0613555A2
(pt)
|
2005-07-04 |
2011-01-18 |
Reddys Lab Ltd Dr |
derivados de tiazóis como ativador de ampk
|
|
WO2007007463A1
(ja)
|
2005-07-11 |
2007-01-18 |
Idemitsu Kosan Co., Ltd. |
電子吸引性置換基を有する含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子
|
|
WO2007007464A1
(ja)
|
2005-07-11 |
2007-01-18 |
Idemitsu Kosan Co., Ltd. |
含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子
|
|
JP2007039406A
(ja)
|
2005-08-05 |
2007-02-15 |
Idemitsu Kosan Co Ltd |
含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子
|
|
JP2007153778A
(ja)
|
2005-12-02 |
2007-06-21 |
Idemitsu Kosan Co Ltd |
含窒素複素環誘導体及びそれを用いた有機エレクトロルミネッセンス素子
|
|
WO2007084390A2
(en)
|
2006-01-13 |
2007-07-26 |
Takeda San Diego, Inc. |
Histone deacetylase inhibitors
|
|
US8518980B2
(en)
|
2006-02-10 |
2013-08-27 |
Summit Corporation Plc |
Treatment of Duchenne muscular dystrophy
|
|
AU2007215247B2
(en)
|
2006-02-10 |
2012-12-13 |
Transtech Pharma, Llc |
Benzazole derivatives, compositions, and methods of use as Aurora kinase inhibitors
|
|
FR2903695B1
(fr)
|
2006-07-13 |
2008-10-24 |
Merck Sante Soc Par Actions Si |
Utilisation de derives d'imidazole activateurs de l'ampk, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
AU2007272795A1
(en)
|
2006-07-14 |
2008-01-17 |
Merck & Co., Inc. |
2-substituted proline bis-amide orexin receptor antagonists
|
|
EP1878724A1
(en)
|
2006-07-15 |
2008-01-16 |
sanofi-aventis |
A regioselective palladium catalyzed synthesis of benzimidazoles and azabenzimidazoles
|
|
TW200840110A
(en)
|
2006-11-20 |
2008-10-01 |
Idemitsu Kosan Co |
Organic electroluminescent device
|
|
EP2091329A4
(en)
|
2006-12-05 |
2011-02-23 |
Univ Nat Chiao Tung |
Indazole CONNECTIONS
|
|
TW200911237A
(en)
|
2007-08-03 |
2009-03-16 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
|
KR20100115789A
(ko)
|
2008-02-04 |
2010-10-28 |
머큐리 테라퓨틱스, 인코포레이티드 |
Ampk 조절자
|
|
CN102361857B
(zh)
|
2008-09-26 |
2015-09-16 |
默沙东公司 |
可用作抗糖尿病剂的环状苯并咪唑衍生物
|
|
EP2348857B1
(en)
|
2008-10-22 |
2016-02-24 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
CN102271511A
(zh)
|
2008-10-29 |
2011-12-07 |
默沙东公司 |
可用作抗糖尿病剂的新颖的环状苯并咪唑衍生物
|
|
JP5557845B2
(ja)
|
2008-10-31 |
2014-07-23 |
メルク・シャープ・アンド・ドーム・コーポレーション |
糖尿病用剤として有用な新規環状ベンゾイミダゾール誘導体
|
|
AU2011218830B2
(en)
|
2010-02-25 |
2014-07-24 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
MX348131B
(es)
|
2011-02-25 |
2017-05-26 |
Merck Sharp & Dohme |
Novedosos derivados de azabencimidazol ciclico utiles como agentes antidiabeticos.
|