AU2002331898A1 - Induction of brown adipocytes by transcription factor nfe2l2 - Google Patents
Induction of brown adipocytes by transcription factor nfe2l2Info
- Publication number
- AU2002331898A1 AU2002331898A1 AU2002331898A AU2002331898A AU2002331898A1 AU 2002331898 A1 AU2002331898 A1 AU 2002331898A1 AU 2002331898 A AU2002331898 A AU 2002331898A AU 2002331898 A AU2002331898 A AU 2002331898A AU 2002331898 A1 AU2002331898 A1 AU 2002331898A1
- Authority
- AU
- Australia
- Prior art keywords
- nfe2l2
- induction
- transcription factor
- brown adipocytes
- adipocytes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32440001P | 2001-09-24 | 2001-09-24 | |
US60/324,400 | 2001-09-24 | ||
PCT/US2002/030266 WO2003026576A2 (en) | 2001-09-24 | 2002-09-24 | Induction of brown adipocytes by transcription factor nfe2l2 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002331898A1 true AU2002331898A1 (en) | 2003-04-07 |
Family
ID=23263411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002331898A Abandoned AU2002331898A1 (en) | 2001-09-24 | 2002-09-24 | Induction of brown adipocytes by transcription factor nfe2l2 |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002331898A1 (en) |
WO (1) | WO2003026576A2 (en) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US7576052B2 (en) | 2003-10-17 | 2009-08-18 | Joslin Diabetes Center, Inc. | Methods and compositions for modulating adipocyte function |
US20080125403A1 (en) | 2004-04-02 | 2008-05-29 | Merck & Co., Inc. | Method of Treating Men with Metabolic and Anthropometric Disorders |
WO2006108023A2 (en) * | 2005-04-04 | 2006-10-12 | Joslin Diabetes Center, Inc. | Methods and compositions for modulating necdin function |
US20100150885A1 (en) | 2005-06-01 | 2010-06-17 | Joslin Diabetes Center, Inc. | Methods and compositions for inducing brown adipogenesis |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
CN103601792B (en) | 2007-06-04 | 2016-06-29 | 协同医药品公司 | It is effective to the guanylate cyclase agonist of gastrointestinal dysfunction, inflammation, cancer and other diseases treatment |
CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
EP3241839B1 (en) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
MX2011004258A (en) | 2008-10-22 | 2011-06-01 | Merck Sharp & Dohme | Novel cyclic benzimidazole derivatives useful anti-diabetic agents. |
JP5557845B2 (en) | 2008-10-31 | 2014-07-23 | メルク・シャープ・アンド・ドーム・コーポレーション | Novel cyclic benzimidazole derivatives useful as antidiabetic agents |
US8476227B2 (en) | 2010-01-22 | 2013-07-02 | Ethicon Endo-Surgery, Inc. | Methods of activating a melanocortin-4 receptor pathway in obese subjects |
US9044606B2 (en) | 2010-01-22 | 2015-06-02 | Ethicon Endo-Surgery, Inc. | Methods and devices for activating brown adipose tissue using electrical energy |
AU2011218830B2 (en) | 2010-02-25 | 2014-07-24 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
KR20150075120A (en) | 2011-02-25 | 2015-07-02 | 머크 샤프 앤드 돔 코포레이션 | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
RU2015106909A (en) | 2012-08-02 | 2016-09-27 | Мерк Шарп И Доум Корп. | ANTI-DIABETIC TRICYCLIC COMPOUNDS |
MX2015010935A (en) | 2013-02-22 | 2015-10-29 | Merck Sharp & Dohme | Antidiabetic bicyclic compounds. |
US9650375B2 (en) | 2013-03-14 | 2017-05-16 | Merck Sharp & Dohme Corp. | Indole derivatives useful as anti-diabetic agents |
WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
AU2014235215A1 (en) | 2013-03-15 | 2015-10-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
CN105764916B (en) | 2013-06-05 | 2021-05-18 | 博士医疗爱尔兰有限公司 | Ultra-pure agonists of guanylate cyclase C, methods of making and using the same |
WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
CA2926685A1 (en) | 2013-10-09 | 2015-04-16 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for downregulation of pro-inflammatory cytokines |
US10092738B2 (en) | 2014-12-29 | 2018-10-09 | Ethicon Llc | Methods and devices for inhibiting nerves when activating brown adipose tissue |
US10080884B2 (en) | 2014-12-29 | 2018-09-25 | Ethicon Llc | Methods and devices for activating brown adipose tissue using electrical energy |
WO2018106518A1 (en) | 2016-12-06 | 2018-06-14 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
EP3558298A4 (en) | 2016-12-20 | 2020-08-05 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4495787B2 (en) * | 1997-05-30 | 2010-07-07 | ダナ−ファーバー キャンサー インスティテュート インク. | PGC-1, a new brown fat PPAR ▲ bottom γ ▼ coactivator |
JP2002536009A (en) * | 1999-02-09 | 2002-10-29 | レキシコン・ジェネティクス・インコーポレーテッド | Human uncoupling protein and polynucleotide encoding the same |
-
2002
- 2002-09-24 WO PCT/US2002/030266 patent/WO2003026576A2/en not_active Application Discontinuation
- 2002-09-24 AU AU2002331898A patent/AU2002331898A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2003026576A3 (en) | 2003-06-26 |
WO2003026576A2 (en) | 2003-04-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |