|
CA2779355C
(en)
|
2009-11-05 |
2018-01-16 |
Glaxosmithkline Llc |
Benzodiazepine bromodomain inhibitor
|
|
AU2010317096B2
(en)
|
2009-11-05 |
2015-03-26 |
Glaxosmithkline Llc |
Benzodiazepine bromodomain inhibitor
|
|
CN103180318B
(zh)
|
2010-05-14 |
2017-05-10 |
达那-法伯癌症研究所 |
雄性避孕组合物以及使用方法
|
|
ES2606958T3
(es)
|
2010-05-14 |
2017-03-28 |
Dana-Farber Cancer Institute, Inc. |
Compuestos de tienotriazolodiazepina para tratar una neoplasia
|
|
CN103154246B
(zh)
|
2010-05-14 |
2015-11-25 |
达那-法伯癌症研究所 |
用于治疗白血病的组合物和方法
|
|
EP2585465B1
(en)
|
2010-06-22 |
2014-11-12 |
GlaxoSmithKline LLC |
Benzotriazolodiazepine compounds inhibitors of bromodomains
|
|
WO2012075456A1
(en)
|
2010-12-02 |
2012-06-07 |
Constellation Pharmaceuticals |
Bromodomain inhibitors and uses thereof
|
|
AR084070A1
(es)
|
2010-12-02 |
2013-04-17 |
Constellation Pharmaceuticals Inc |
Inhibidores del bromodominio y usos de los mismos
|
|
GB201106743D0
(en)
*
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB201106750D0
(en)
*
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2012151512A2
(en)
|
2011-05-04 |
2012-11-08 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
GB201107325D0
(en)
|
2011-05-04 |
2011-06-15 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2012174487A2
(en)
|
2011-06-17 |
2012-12-20 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
WO2013027168A1
(en)
|
2011-08-22 |
2013-02-28 |
Pfizer Inc. |
Novel heterocyclic compounds as bromodomain inhibitors
|
|
WO2013033269A1
(en)
*
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bioorthogonal monomers capable of dimerizing and targeting bromodomains and methods of using same
|
|
TWI602820B
(zh)
|
2012-06-06 |
2017-10-21 |
星宿藥物公司 |
溴域抑制劑及其用途
|
|
WO2013184878A1
(en)
|
2012-06-06 |
2013-12-12 |
Constellation Pharmaceuticals, Inc. |
Benzo [b] isoxazoloazepine bromodomain inhibitors and uses thereof
|
|
US9073878B2
(en)
|
2012-11-21 |
2015-07-07 |
Zenith Epigenetics Corp. |
Cyclic amines as bromodomain inhibitors
|
|
US9765039B2
(en)
|
2012-11-21 |
2017-09-19 |
Zenith Epigenetics Ltd. |
Biaryl derivatives as bromodomain inhibitors
|
|
JP2016507496A
(ja)
|
2012-12-21 |
2016-03-10 |
ゼニス・エピジェネティクス・コーポレイションZenith Epigenetics Corp. |
ブロモドメイン阻害剤としての新規複素環式化合物
|
|
JP2016510039A
(ja)
*
|
2013-02-28 |
2016-04-04 |
ワシントン・ユニバーシティWashington University |
ブロモドメイン阻害剤によるヒトサイトメガロウイルス感染および疾患の治療方法
|
|
CN105189461B
(zh)
*
|
2013-03-14 |
2018-05-15 |
葛兰素史克知识产权第二有限公司 |
2,3-二取代的1-酰基-4-氨基-1,2,3,4-四氢喹啉衍生物和它们作为溴结构域抑制剂的用途
|
|
WO2014159392A1
(en)
|
2013-03-14 |
2014-10-02 |
Dana-Farber Cancer Institute, Inc. |
Bromodomain binding reagents and uses thereof
|
|
EA035469B1
(ru)
|
2013-03-15 |
2020-06-22 |
Инсайт Холдингс Корпорейшн |
Трициклические гетероциклы как ингибиторы белков бэт
|
|
EA027139B1
(ru)
|
2013-04-26 |
2017-06-30 |
Бейджин, Лтд. |
Замещенные 5-(3,5-диметилизоксазол-4-ил)индолин-2-оны
|
|
CN105473581B
(zh)
|
2013-06-21 |
2019-04-23 |
齐尼思表观遗传学有限公司 |
作为溴结构域抑制剂的新取代的双环化合物
|
|
KR102307566B1
(ko)
|
2013-06-21 |
2021-10-05 |
제니쓰 에피제네틱스 리미티드 |
신규한 바이사이클릭 브로모도메인 억제제
|
|
EP3019502B1
(en)
|
2013-07-08 |
2017-05-17 |
Incyte Holdings Corporation |
Tricyclic heterocycles as bet protein inhibitors
|
|
BR112016001457A2
(pt)
|
2013-07-25 |
2017-08-29 |
Dana Farber Cancer Inst Inc |
Inibidores de fatores de transcrição e usos dos mesmos
|
|
CA2919948C
(en)
|
2013-07-31 |
2020-07-21 |
Zenith Epigenetics Corp. |
Novel quinazolinones as bromodomain inhibitors
|
|
US11446309B2
(en)
|
2013-11-08 |
2022-09-20 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy for cancer using bromodomain and extra-terminal (BET) protein inhibitors
|
|
US9315501B2
(en)
|
2013-11-26 |
2016-04-19 |
Incyte Corporation |
Bicyclic heterocycles as BET protein inhibitors
|
|
US9399640B2
(en)
|
2013-11-26 |
2016-07-26 |
Incyte Corporation |
Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors
|
|
WO2015085925A1
(en)
*
|
2013-12-10 |
2015-06-18 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
US9309246B2
(en)
|
2013-12-19 |
2016-04-12 |
Incyte Corporation |
Tricyclic heterocycles as BET protein inhibitors
|
|
WO2015117083A1
(en)
|
2014-01-31 |
2015-08-06 |
Dana-Farber Cancer Institute, Inc. |
Diazepane derivatives and uses thereof
|
|
MX2016009974A
(es)
|
2014-01-31 |
2016-10-31 |
Dana Farber Cancer Inst Inc |
Derivados de diaminopirimidina bencensulfona y sus usos.
|
|
EP3099693A4
(en)
|
2014-01-31 |
2017-08-16 |
Dana-Farber Cancer Institute, Inc. |
Uses of diazepane derivatives
|
|
WO2015131113A1
(en)
|
2014-02-28 |
2015-09-03 |
Tensha Therapeutics, Inc. |
Treatment of conditions associated with hyperinsulinaemia
|
|
SMT202000133T1
(it)
|
2014-04-23 |
2020-05-08 |
Incyte Corp |
1h-pirrolo[2,3-c]piridin-7(6h)-oni e pirazolo[3,4-c]piridin-7(6h)-oni come inibitori di proteine bet
|
|
CN106687463B
(zh)
|
2014-06-20 |
2019-04-09 |
星座制药公司 |
一种乙酰胺类化合物的晶型
|
|
RU2017104897A
(ru)
|
2014-08-08 |
2018-09-10 |
Дана-Фарбер Кэнсер Инститьют, Инк. |
Производные диазепана и их применения
|
|
WO2016022970A1
(en)
|
2014-08-08 |
2016-02-11 |
Dana-Farber Cancer Institute, Inc. |
Dihydropteridinone derivatives and uses thereof
|
|
WO2016038120A1
(en)
|
2014-09-12 |
2016-03-17 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Tetrahydroquinoline derivatives as bromodomain inhibitors
|
|
JP6599979B2
(ja)
|
2014-09-15 |
2019-10-30 |
インサイト・コーポレイション |
Betタンパク質阻害剤として用いるための三環式複素環化合物
|
|
US10179125B2
(en)
|
2014-12-01 |
2019-01-15 |
Zenith Epigenetics Ltd. |
Substituted pyridines as bromodomain inhibitors
|
|
HK1245246A1
(zh)
|
2014-12-01 |
2018-08-24 |
恒翼生物医药科技(上海)有限公司 |
作为溴域抑制剂的取代吡啶酮
|
|
WO2016092375A1
(en)
|
2014-12-11 |
2016-06-16 |
Zenith Epigenetics Corp. |
Substituted heterocycles as bromodomain inhibitors
|
|
CN107406438B
(zh)
|
2014-12-17 |
2021-05-14 |
恒翼生物医药科技(上海)有限公司 |
溴结构域的抑制剂
|
|
GB201504694D0
(en)
|
2015-03-19 |
2015-05-06 |
Glaxosmithkline Ip Dev Ltd |
Covalent conjugates
|
|
CN107709314A
(zh)
|
2015-06-11 |
2018-02-16 |
巴斯利尔药物国际股份公司 |
外排泵抑制剂及其治疗性用途
|
|
CA2986441A1
(en)
|
2015-06-12 |
2016-12-15 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
|
WO2016203335A1
(en)
|
2015-06-18 |
2016-12-22 |
Pfizer Inc. |
Novel pyrido[2,3-b]pyrazinones as bet-family bromodomain inhibitors
|
|
AU2016283020A1
(en)
|
2015-06-26 |
2018-01-04 |
Tensha Therapeutics, Inc. |
Treatment of nut midline carcinoma
|
|
RU2018112953A
(ru)
|
2015-09-11 |
2019-10-14 |
Дана-Фарбер Кэнсер Инститьют, Инк. |
Ацетамидтиенотриазолодиазепины и пути их применения
|
|
US11306105B2
(en)
|
2015-09-11 |
2022-04-19 |
Dana-Farber Cancer Institute, Inc. |
Cyano thienotriazolodiazepines and uses thereof
|
|
WO2017075377A1
(en)
|
2015-10-29 |
2017-05-04 |
Incyte Corporation |
Amorphous solid form of a bet protein inhibitor
|
|
CR20180336A
(es)
|
2015-11-25 |
2018-08-06 |
Dana Farber Cancer Inst Inc |
Inhibidores de bromodominio bivalentes y usos de los mismos
|
|
WO2017205536A2
(en)
*
|
2016-05-24 |
2017-11-30 |
Genentech, Inc. |
Therapeutic compounds and uses thereof
|
|
CN109715625B
(zh)
|
2016-06-20 |
2022-04-19 |
因赛特公司 |
Bet抑制剂的结晶固体形式
|
|
US11028051B2
(en)
*
|
2016-12-13 |
2021-06-08 |
St. Jude Children's Research Hospital |
Tetrahydroquinoline-based bromodomain inhibitors
|
|
WO2021175432A1
(en)
|
2020-03-04 |
2021-09-10 |
Boehringer Ingelheim International Gmbh |
Method for administration of an anti cancer agent
|
|
US11833155B2
(en)
|
2020-06-03 |
2023-12-05 |
Incyte Corporation |
Combination therapy for treatment of myeloproliferative neoplasms
|
|
CN114751836B
(zh)
*
|
2021-02-23 |
2024-05-31 |
四川青木制药有限公司 |
3-(4-甲基-1h-咪唑-1-基)-5-(三氟甲基)苯胺合成方法及其中间体
|
|
CA3255932A1
(en)
|
2022-04-19 |
2023-10-26 |
Nuevolution A/S |
ACTIVE COMPOUNDS AGAINST BROMODOMAINS
|