JP2012532883A5 - - Google Patents

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Publication number
JP2012532883A5
JP2012532883A5 JP2012519731A JP2012519731A JP2012532883A5 JP 2012532883 A5 JP2012532883 A5 JP 2012532883A5 JP 2012519731 A JP2012519731 A JP 2012519731A JP 2012519731 A JP2012519731 A JP 2012519731A JP 2012532883 A5 JP2012532883 A5 JP 2012532883A5
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Japan
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compound according
compound
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substituted
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JP2012519731A
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English (en)
Japanese (ja)
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JP2012532883A (ja
JP5925121B2 (ja
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Priority claimed from PCT/US2010/041379 external-priority patent/WO2011005969A2/en
Publication of JP2012532883A publication Critical patent/JP2012532883A/ja
Publication of JP2012532883A5 publication Critical patent/JP2012532883A5/ja
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Publication of JP5925121B2 publication Critical patent/JP5925121B2/ja
Expired - Fee Related legal-status Critical Current
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JP2012519731A 2009-07-10 2010-07-08 副腎皮質ステロイド合成を阻害しないエトミデート類似体 Expired - Fee Related JP5925121B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22475109P 2009-07-10 2009-07-10
US61/224,751 2009-07-10
PCT/US2010/041379 WO2011005969A2 (en) 2009-07-10 2010-07-08 Etomidate analogues that do not inhibit adrenocortical steroid synthesis

Publications (3)

Publication Number Publication Date
JP2012532883A JP2012532883A (ja) 2012-12-20
JP2012532883A5 true JP2012532883A5 (enExample) 2013-08-22
JP5925121B2 JP5925121B2 (ja) 2016-05-25

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ID=43429834

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012519731A Expired - Fee Related JP5925121B2 (ja) 2009-07-10 2010-07-08 副腎皮質ステロイド合成を阻害しないエトミデート類似体

Country Status (9)

Country Link
US (2) US8765973B2 (enExample)
EP (1) EP2451779B1 (enExample)
JP (1) JP5925121B2 (enExample)
CN (1) CN102548964B (enExample)
AU (1) AU2010271345B2 (enExample)
BR (1) BR112012000606A2 (enExample)
CA (1) CA2767112C (enExample)
RU (1) RU2559888C2 (enExample)
WO (1) WO2011005969A2 (enExample)

Families Citing this family (15)

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Publication number Priority date Publication date Assignee Title
DK2802325T3 (en) 2012-01-13 2017-03-13 Massachusetts Gen Hospital ANESTHETIC RELATIONS AND RELATED APPLICATIONS THEREOF
AR093468A1 (es) * 2012-11-14 2015-06-10 Teijin Pharma Ltd Derivados de piridina
EP3206683A4 (en) 2014-10-16 2018-06-13 The Board of Trustees of the Leland Stanford Junior University Novel methods, compounds, and compositions for anesthesia
AU2016334247B2 (en) 2015-10-07 2021-09-30 Apellis Pharmaceuticals, Inc. Dosing regimens
JP6983416B2 (ja) * 2015-10-10 2021-12-17 ジアンス・エンファルオカン・ファーマスーティカル・リサーチ・アンド・デベロップメント・カンパニー・リミテッドJiangsu Nhwaluokang Pharmceutical Research And Development Co., Ltd. エトミデート誘導体ならびにその中間体、調製方法および使用
CN107445898A (zh) * 2016-05-30 2017-12-08 四川海思科制药有限公司 N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途
CN107522662A (zh) * 2016-06-16 2017-12-29 四川海思科制药有限公司 N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途
CN107641105A (zh) * 2016-07-22 2018-01-30 四川海思科制药有限公司 N‑取代咪唑羧酸酯类化合物及其制备方法和在医药上的用途
CN107652239B (zh) * 2017-02-24 2020-08-04 四川大学华西医院 N-取代咪唑羧酸酯类化合物、制备方法及用途
EP4585228A3 (en) 2017-04-07 2025-10-15 Apellis Pharmaceuticals, Inc. Dosing regimens and related compositions and methods
WO2019118938A1 (en) 2017-12-15 2019-06-20 Apellis Pharmaceuticals, Inc. Dosing regimens and related compositions and methods
CN109776512A (zh) * 2018-01-30 2019-05-21 成都安诺晨创医药科技有限公司 一种n-取代咪唑甲酸酯类衍生物及其用途
CN110003188B (zh) * 2019-03-27 2022-08-26 成都麻沸散医药科技有限公司 取代吡咯甲酸酯类衍生物及其用途
CN110669017B (zh) * 2019-10-11 2023-08-04 成都麻沸散医药科技有限公司 多取代三唑甲酸酯类衍生物及其用途
CN112174890B (zh) * 2020-10-09 2022-05-27 成都麻沸散医药科技有限公司 酮取代杂环化合物及其麻醉作用

Family Cites Families (17)

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Publication number Priority date Publication date Assignee Title
US3354173A (en) 1964-04-16 1967-11-21 Janssen Pharmaceutica Nv Imidazole carboxylates
US4038286A (en) 1975-03-10 1977-07-26 Janssen Pharmaceutica N.V. Racemates and optical isomers of 1-(1-phenylethyl)-1h-imidazole-5-carboylic acid derivatives
GR64915B (en) 1978-09-14 1980-06-09 Janssen Pharmaceutica Nv Improved etomidate-containing compositions
US4878940A (en) 1987-04-02 1989-11-07 Janssen Pharmaceutica N.V. Herbicidal 1,5-substituted 1H-imidazoles
US5041554A (en) * 1989-01-31 1991-08-20 Merrell Dow Pharmaceuticals Inc. Novel aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds useful in treating interleukin-1 mediated conditions
ZA90554B (en) * 1989-01-31 1990-10-31 Merrell Pharma Inc Novel aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds useful in treating interleukin-1 mediated conditions
US5019583A (en) 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics
US5242939A (en) 1990-09-28 1993-09-07 Warner-Lambert Company Anilide derivatives with angiotensin ii antagonist properties
JP3374922B2 (ja) 1991-05-09 2003-02-10 日産化学工業株式会社 複素環式第3級アミンの製造方法
JPH06345728A (ja) 1993-06-11 1994-12-20 Nissan Chem Ind Ltd N−置換アゾール誘導体の製造方法
US5466700A (en) 1993-08-30 1995-11-14 Glaxo Wellcome Inc. Anesthetic use of N-phenyl-N-(4-piperidinyl)amides
US5756528A (en) 1995-06-06 1998-05-26 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
RU2160265C1 (ru) * 2000-03-17 2000-12-10 Научно-исследовательский институт физической и органической химии Ростовского государственного университета Дигидрохлорид 1-(3-пирролидинопропил)-2-фенилимидазо [1,2-а]-бензимидазола, обладающий местноанестезирующим действием
US20030055023A1 (en) 2001-03-20 2003-03-20 Rajewski Roger A. Formulations containing etomidate and a sulfoalkyl ether cyclodextrin
JP2005514412A (ja) * 2001-12-27 2005-05-19 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 中枢神経系疾患を処置するために有用なアロイルピロールヘテロアリールおよびメタノール類
JP2008510726A (ja) 2004-08-20 2008-04-10 エントレメッド インコーポレイテッド プロテイナーゼ活性化受容体アンタゴニストを含む組成物および方法
JP5580287B2 (ja) * 2008-03-31 2014-08-27 ザ ジェネラル ホスピタル コーポレイション 改善された薬物速度論的および薬力学的特性を有するエトミデート類似体

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