JP2013545785A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013545785A5 JP2013545785A5 JP2013543799A JP2013543799A JP2013545785A5 JP 2013545785 A5 JP2013545785 A5 JP 2013545785A5 JP 2013543799 A JP2013543799 A JP 2013543799A JP 2013543799 A JP2013543799 A JP 2013543799A JP 2013545785 A5 JP2013545785 A5 JP 2013545785A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- compound
- motomeko
- group
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10195467.5 | 2010-12-16 | ||
| EP10195467 | 2010-12-16 | ||
| PCT/EP2011/073008 WO2012080446A1 (en) | 2010-12-16 | 2011-12-16 | Benzimidazole respiratory syncytial virus inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013545785A JP2013545785A (ja) | 2013-12-26 |
| JP2013545785A5 true JP2013545785A5 (enExample) | 2014-06-26 |
| JP6005656B2 JP6005656B2 (ja) | 2016-10-12 |
Family
ID=43875271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013543799A Expired - Fee Related JP6005656B2 (ja) | 2010-12-16 | 2011-12-16 | ベンゾイミダゾール呼吸合胞体ウイルス阻害剤 |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US8865705B2 (enExample) |
| EP (1) | EP2651903B1 (enExample) |
| JP (1) | JP6005656B2 (enExample) |
| KR (1) | KR101876240B1 (enExample) |
| CN (2) | CN103313974A (enExample) |
| AR (1) | AR085203A1 (enExample) |
| AU (1) | AU2011343255B2 (enExample) |
| BR (1) | BR112013012137A2 (enExample) |
| CA (1) | CA2821999C (enExample) |
| CL (1) | CL2013001713A1 (enExample) |
| CY (1) | CY1117751T1 (enExample) |
| DK (1) | DK2651903T3 (enExample) |
| EA (1) | EA022972B1 (enExample) |
| ES (1) | ES2576180T3 (enExample) |
| HK (1) | HK1247616A1 (enExample) |
| HR (1) | HRP20160650T1 (enExample) |
| HU (1) | HUE029247T2 (enExample) |
| IL (1) | IL225640A (enExample) |
| MX (1) | MX340030B (enExample) |
| MY (1) | MY156641A (enExample) |
| NZ (1) | NZ609450A (enExample) |
| PH (1) | PH12013500796A1 (enExample) |
| PL (1) | PL2651903T3 (enExample) |
| PT (1) | PT2651903E (enExample) |
| SG (1) | SG190766A1 (enExample) |
| SI (1) | SI2651903T1 (enExample) |
| TW (1) | TWI530495B (enExample) |
| UA (1) | UA112298C2 (enExample) |
| WO (1) | WO2012080446A1 (enExample) |
| ZA (1) | ZA201304424B (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI515187B (zh) | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| TWI501967B (zh) * | 2010-12-16 | 2015-10-01 | Janssen R&D Ireland | 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類 |
| TWI527814B (zh) * | 2010-12-16 | 2016-04-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類 |
| TWI541241B (zh) | 2010-12-16 | 2016-07-11 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類 |
| TWI530495B (zh) | 2010-12-16 | 2016-04-21 | 健生科學愛爾蘭無限公司 | 苯并咪唑呼吸道融合病毒抑制劑 |
| US20150111868A1 (en) | 2012-06-15 | 2015-04-23 | Jansen R&D Ireland | Novel 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents |
| WO2013186334A1 (en) * | 2012-06-15 | 2013-12-19 | Janssen R&D Ireland | 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with benzimidazoles as respiratory syncytial virus antiviral agents |
| ES2600318T3 (es) * | 2012-07-10 | 2017-02-08 | F. Hoffmann-La Roche Ag | Nuevos indazoles para el tratamiento y profilaxis de infección por virus sincitial respiratorio |
| MY172021A (en) * | 2012-10-16 | 2019-11-12 | Janssen Sciences Ireland Uc | Rsv antiviral compounds |
| AU2014209853B2 (en) * | 2013-01-28 | 2017-12-21 | Janssen Sciences Ireland Uc | Quinoxalinones and dihydroquinoxalinones as respiratory syncytial virus antiviral agents |
| CN105392787B (zh) * | 2013-05-14 | 2017-11-24 | 豪夫迈·罗氏有限公司 | 用于治疗和预防呼吸道合胞病毒感染的氮杂‑氧代‑吲哚 |
| EP2997028A1 (en) | 2013-05-14 | 2016-03-23 | F.Hoffmann-La Roche Ag | Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection |
| HK1222855A1 (zh) * | 2013-08-15 | 2017-07-14 | F. Hoffmann-La Roche Ag | 新的用於治疗和预防呼吸道合胞病毒感染的氮杂-氧代-吲哚 |
| AU2014308991B2 (en) | 2013-08-21 | 2019-02-14 | Janssen Biopharma, Inc. | Antiviral compounds |
| WO2015065336A1 (en) * | 2013-10-29 | 2015-05-07 | Medivir Ab | Respiratory syncytial virus inhibitors |
| TWI671299B (zh) | 2014-04-14 | 2019-09-11 | 愛爾蘭商健生科學愛爾蘭無限公司 | 作為ｒｓｖ抗病毒化合物之螺脲化合物 |
| PE20170673A1 (es) * | 2014-08-05 | 2017-05-22 | Alios Biopharma Inc | Terapia de combinacion para tratar una paramixovirus |
| MA41614A (fr) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | Composés antiviraux |
| DK3324977T3 (da) | 2015-07-22 | 2022-10-17 | Enanta Pharm Inc | Benzodiazepinderivater som rsv-inhibitorer |
| EP3402799B1 (en) | 2016-01-15 | 2022-05-04 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as rsv inhibitors |
| CN110809472B (zh) | 2017-02-16 | 2023-05-23 | 英安塔制药有限公司 | 用于制备苯二氮䓬衍生物的方法 |
| US11091501B2 (en) | 2017-06-30 | 2021-08-17 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as RSV inhibitors |
| BR112020006334A2 (pt) | 2017-09-29 | 2020-09-24 | Enanta Pharmaceuticals, Inc. | combinação de agentes farmacêuticos como inibidores de rsv |
| CA3080138A1 (en) | 2017-11-13 | 2019-05-16 | Enanta Pharmaceuticals, Inc. | Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives |
| BR112021018335A2 (pt) | 2019-03-18 | 2021-11-23 | Enanta Pharm Inc | Derivados de benzodiazepina como inibidores de rsv |
| AU2020357452B2 (en) | 2019-10-04 | 2026-01-29 | Enanta Pharmaceuticals, Inc | Antiviral heterocyclic compounds |
| US11505558B1 (en) | 2019-10-04 | 2022-11-22 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| UY39032A (es) | 2020-01-24 | 2021-07-30 | Enanta Pharm Inc | Compuestos heterocíclicos como agentes antivirales |
| EP4165034A1 (en) | 2020-06-11 | 2023-04-19 | Janssen Sciences Ireland Unlimited Company | Hemi (l)-tartrate forms of 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1h-indol-2 yl} methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2h-imidazo[4,5-c]pyridin-2-one and pharmaceutical compositions comprising the same |
| WO2022010882A1 (en) | 2020-07-07 | 2022-01-13 | Enanta Pharmaceuticals, Inc, | Dihydroquinoxaline and dihydropyridopyrazine derivatives as rsv inhibitors |
| US11945824B2 (en) | 2020-10-19 | 2024-04-02 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as anti-viral agents |
| WO2022182861A1 (en) | 2021-02-26 | 2022-09-01 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| US12612412B2 (en) | 2021-02-26 | 2026-04-28 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| AR129003A1 (es) | 2022-04-07 | 2024-07-03 | Enanta Pharm Inc | Compuestos heterocíclicos antivirales |
| WO2023211997A1 (en) | 2022-04-27 | 2023-11-02 | Enanta Pharmaceuticals, Inc. | Antiviral compounds |
| WO2024174953A1 (zh) * | 2023-02-21 | 2024-08-29 | 苏州隆博泰药业有限公司 | 苯并咪唑类衍生物及其医药用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002514162A (ja) | 1996-07-08 | 2002-05-14 | デュポン ファーマシューティカルズ カンパニー | Ｘａ因子阻害薬およびトロンビン阻害薬としてのアミジノインドール類、アミジノアゾール類、およびそれらの類似体 |
| AU1099000A (en) | 1998-10-05 | 2000-04-26 | Axys Pharmaceuticals, Inc. | Novel compounds and compositions for treating hepatitis c infections |
| IL147327A0 (en) | 1999-06-28 | 2002-08-14 | Janssen Pharmaceutica Nv | Respiratory syncytial virus replication inhibitors |
| SI1196408T1 (en) | 1999-06-28 | 2005-02-28 | Janssen Pharmaceutica N.V. | Respiratory syncytial virus replication inhibitors |
| US6534535B1 (en) | 1999-08-12 | 2003-03-18 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| US6489338B2 (en) * | 2000-06-13 | 2002-12-03 | Bristol-Myers Squibb Company | Imidazopyridine and imidazopyrimidine antiviral agents |
| US6506738B1 (en) | 2000-09-27 | 2003-01-14 | Bristol-Myers Squibb Company | Benzimidazolone antiviral agents |
| US6919331B2 (en) | 2001-12-10 | 2005-07-19 | Bristol-Myers Squibb Company | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents |
| WO2004043913A2 (en) | 2002-11-08 | 2004-05-27 | Trimeris, Inc. | Hetero-substituted benzimidazole compounds and antiviral uses thereof |
| TWI530495B (zh) | 2010-12-16 | 2016-04-21 | 健生科學愛爾蘭無限公司 | 苯并咪唑呼吸道融合病毒抑制劑 |
| TWI515187B (zh) | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| TWI541241B (zh) | 2010-12-16 | 2016-07-11 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類 |
| TWI501967B (zh) | 2010-12-16 | 2015-10-01 | Janssen R&D Ireland | 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類 |
| TWI527814B (zh) | 2010-12-16 | 2016-04-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類 |
-
2011
- 2011-12-15 TW TW100146390A patent/TWI530495B/zh not_active IP Right Cessation
- 2011-12-16 HU HUE11802054A patent/HUE029247T2/en unknown
- 2011-12-16 WO PCT/EP2011/073008 patent/WO2012080446A1/en not_active Ceased
- 2011-12-16 AR ARP110104739A patent/AR085203A1/es active IP Right Grant
- 2011-12-16 JP JP2013543799A patent/JP6005656B2/ja not_active Expired - Fee Related
- 2011-12-16 UA UAA201305027A patent/UA112298C2/uk unknown
- 2011-12-16 MY MYPI2013001281A patent/MY156641A/en unknown
- 2011-12-16 HR HRP20160650TT patent/HRP20160650T1/hr unknown
- 2011-12-16 NZ NZ609450A patent/NZ609450A/en not_active IP Right Cessation
- 2011-12-16 CN CN2011800602778A patent/CN103313974A/zh active Pending
- 2011-12-16 KR KR1020137016944A patent/KR101876240B1/ko not_active Expired - Fee Related
- 2011-12-16 BR BR112013012137A patent/BR112013012137A2/pt not_active Application Discontinuation
- 2011-12-16 DK DK11802054.4T patent/DK2651903T3/da active
- 2011-12-16 MX MX2013006886A patent/MX340030B/es active IP Right Grant
- 2011-12-16 SG SG2013026711A patent/SG190766A1/en unknown
- 2011-12-16 PT PT118020544T patent/PT2651903E/pt unknown
- 2011-12-16 PH PH1/2013/500796A patent/PH12013500796A1/en unknown
- 2011-12-16 PL PL11802054.4T patent/PL2651903T3/pl unknown
- 2011-12-16 CN CN201710103106.8A patent/CN107417683A/zh active Pending
- 2011-12-16 EA EA201390888A patent/EA022972B1/ru not_active IP Right Cessation
- 2011-12-16 CA CA2821999A patent/CA2821999C/en active Active
- 2011-12-16 US US13/993,107 patent/US8865705B2/en active Active
- 2011-12-16 SI SI201130853A patent/SI2651903T1/sl unknown
- 2011-12-16 EP EP11802054.4A patent/EP2651903B1/en active Active
- 2011-12-16 AU AU2011343255A patent/AU2011343255B2/en not_active Ceased
- 2011-12-16 ES ES11802054.4T patent/ES2576180T3/es active Active
-
2013
- 2013-04-09 IL IL225640A patent/IL225640A/en active IP Right Grant
- 2013-06-13 CL CL2013001713A patent/CL2013001713A1/es unknown
- 2013-06-14 ZA ZA2013/04424A patent/ZA201304424B/en unknown
-
2016
- 2016-06-22 CY CY20161100561T patent/CY1117751T1/el unknown
-
2018
- 2018-05-31 HK HK18107115.5A patent/HK1247616A1/zh unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013545785A5 (enExample) | ||
| JP2014503525A5 (enExample) | ||
| RU2477723C2 (ru) | Ингибиторы протеинкиназ (варианты), их применение для лечения онкологических заболеваний и фармацевтическая композиция на их основе | |
| JP2015505296A5 (enExample) | ||
| JP2016523955A5 (enExample) | ||
| JP2014511892A5 (enExample) | ||
| JP2015537020A5 (enExample) | ||
| JP2014506907A5 (enExample) | ||
| JP2014507455A5 (enExample) | ||
| JP2017504635A5 (enExample) | ||
| JP2012092103A5 (enExample) | ||
| JP2013510120A5 (enExample) | ||
| JP2016503793A5 (enExample) | ||
| JP2014500861A5 (enExample) | ||
| JP2010523522A5 (enExample) | ||
| JP2016515560A5 (enExample) | ||
| JP2016518437A5 (enExample) | ||
| JP2013032389A5 (enExample) | ||
| JP2016513130A5 (enExample) | ||
| JP2013537203A5 (enExample) | ||
| JP2014511891A5 (enExample) | ||
| JP2013534248A5 (enExample) | ||
| JP2013542261A5 (enExample) | ||
| JP2019516739A5 (enExample) | ||
| EP2607363A4 (en) | CONDENSED RING COMPOUND FOR USE AS MINERALOCORTICOID RECEPTOR ANTAGONISTS |