JP2013545785A5 - - Google Patents
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- Publication number
- JP2013545785A5 JP2013545785A5 JP2013543799A JP2013543799A JP2013545785A5 JP 2013545785 A5 JP2013545785 A5 JP 2013545785A5 JP 2013543799 A JP2013543799 A JP 2013543799A JP 2013543799 A JP2013543799 A JP 2013543799A JP 2013545785 A5 JP2013545785 A5 JP 2013545785A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- compound
- motomeko
- group
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10195467.5 | 2010-12-16 | ||
| EP10195467 | 2010-12-16 | ||
| PCT/EP2011/073008 WO2012080446A1 (en) | 2010-12-16 | 2011-12-16 | Benzimidazole respiratory syncytial virus inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013545785A JP2013545785A (ja) | 2013-12-26 |
| JP2013545785A5 true JP2013545785A5 (enExample) | 2014-06-26 |
| JP6005656B2 JP6005656B2 (ja) | 2016-10-12 |
Family
ID=43875271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013543799A Expired - Fee Related JP6005656B2 (ja) | 2010-12-16 | 2011-12-16 | ベンゾイミダゾール呼吸合胞体ウイルス阻害剤 |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US8865705B2 (enExample) |
| EP (1) | EP2651903B1 (enExample) |
| JP (1) | JP6005656B2 (enExample) |
| KR (1) | KR101876240B1 (enExample) |
| CN (2) | CN107417683A (enExample) |
| AR (1) | AR085203A1 (enExample) |
| AU (1) | AU2011343255B2 (enExample) |
| BR (1) | BR112013012137A2 (enExample) |
| CA (1) | CA2821999C (enExample) |
| CL (1) | CL2013001713A1 (enExample) |
| CY (1) | CY1117751T1 (enExample) |
| DK (1) | DK2651903T3 (enExample) |
| EA (1) | EA022972B1 (enExample) |
| ES (1) | ES2576180T3 (enExample) |
| HK (1) | HK1247616A1 (enExample) |
| HR (1) | HRP20160650T1 (enExample) |
| HU (1) | HUE029247T2 (enExample) |
| IL (1) | IL225640A (enExample) |
| MX (1) | MX340030B (enExample) |
| MY (1) | MY156641A (enExample) |
| NZ (1) | NZ609450A (enExample) |
| PH (1) | PH12013500796A1 (enExample) |
| PL (1) | PL2651903T3 (enExample) |
| PT (1) | PT2651903E (enExample) |
| SG (1) | SG190766A1 (enExample) |
| SI (1) | SI2651903T1 (enExample) |
| TW (1) | TWI530495B (enExample) |
| UA (1) | UA112298C2 (enExample) |
| WO (1) | WO2012080446A1 (enExample) |
| ZA (1) | ZA201304424B (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI515187B (zh) | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| TWI530495B (zh) | 2010-12-16 | 2016-04-21 | 健生科學愛爾蘭無限公司 | 苯并咪唑呼吸道融合病毒抑制劑 |
| TWI527814B (zh) * | 2010-12-16 | 2016-04-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類 |
| TWI501967B (zh) | 2010-12-16 | 2015-10-01 | Janssen R&D Ireland | 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類 |
| TWI541241B (zh) | 2010-12-16 | 2016-07-11 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類 |
| CA2873920C (en) | 2012-06-15 | 2021-07-20 | Janssen R&D Ireland | 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents |
| WO2013186334A1 (en) * | 2012-06-15 | 2013-12-19 | Janssen R&D Ireland | 1,3-dihydro-2h-benzimidazol-2-one derivatives substituted with benzimidazoles as respiratory syncytial virus antiviral agents |
| BR112015000392A2 (pt) * | 2012-07-10 | 2017-06-27 | Hoffmann La Roche | novos indazóis para o tratamento e profilaxia da infecção por vírus sincicial respiratório |
| AU2013334001B2 (en) | 2012-10-16 | 2017-07-20 | Janssen Sciences Ireland Uc | RSV antiviral compounds |
| JP6383735B2 (ja) * | 2013-01-28 | 2018-08-29 | ヤンセン・サイエンシズ・アイルランド・ユーシー | Ｒｓウイルスの抗ウイルス剤としてのキノキサリノンおよびジヒドロキノキサリノン |
| JP2016518421A (ja) | 2013-05-14 | 2016-06-23 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 呼吸器合胞体ウイルス感染症の処置および予防のためのアザ−オキソ−インドール |
| HK1222855A1 (zh) | 2013-08-15 | 2017-07-14 | F. Hoffmann-La Roche Ag | 新的用於治疗和预防呼吸道合胞病毒感染的氮杂-氧代-吲哚 |
| CA2921294C (en) | 2013-08-21 | 2023-05-16 | Alios Biopharma, Inc. | Antiviral compounds |
| WO2015065336A1 (en) * | 2013-10-29 | 2015-05-07 | Medivir Ab | Respiratory syncytial virus inhibitors |
| TWI671299B (zh) | 2014-04-14 | 2019-09-11 | 愛爾蘭商健生科學愛爾蘭無限公司 | 作為ｒｓｖ抗病毒化合物之螺脲化合物 |
| MA40404A (fr) * | 2014-08-05 | 2017-06-14 | Alios Biopharma Inc | Polythérapie pour traiter un paramyxovirus |
| MA41614A (fr) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | Composés antiviraux |
| MY197231A (en) | 2015-07-22 | 2023-06-06 | Enanta Pharm Inc | Benzodiazepine derivatives as rsv inhibitors |
| CN108699077B (zh) | 2016-01-15 | 2021-03-02 | 英安塔制药有限公司 | 作为rsv抑制剂的杂环化合物 |
| WO2018152413A1 (en) | 2017-02-16 | 2018-08-23 | Enanta Pharmaceuticals, Inc. | Processes for the preparation of benzodiazepine derivatives |
| WO2019006295A1 (en) | 2017-06-30 | 2019-01-03 | Enanta Pharmaceuticals, Inc. | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS |
| CN111386118B (zh) | 2017-09-29 | 2023-05-09 | 英安塔制药有限公司 | 作为rsv抑制剂的组合药物剂 |
| MX394621B (es) | 2017-11-13 | 2025-03-24 | Enanta Pharm Inc | Procesos para la resolucion de los derivados de la benzodiazepina-2-ona y de la benzoazepin-2-ona |
| WO2020190935A1 (en) | 2019-03-18 | 2020-09-24 | Enanta Pharmaceuticals, Inc. | Benzodiazepine derivatives as rsv inhibitors |
| US11505558B1 (en) | 2019-10-04 | 2022-11-22 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| PH12022550783A1 (en) | 2019-10-04 | 2023-07-31 | Enanta Pharm Inc | Antiviral heterocyclic compounds |
| UY39032A (es) | 2020-01-24 | 2021-07-30 | Enanta Pharm Inc | Compuestos heterocíclicos como agentes antivirales |
| JP2023528969A (ja) | 2020-06-11 | 2023-07-06 | ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー | ３－（｛５－クロロ－１－［３－（メチルスルホニル）プロピル］－１Ｈ－インドール－２ イル｝メチル）－１－（２，２，２－トリフルオロエチル）－１，３－ジヒドロ－２Ｈ－イミダゾ［４，５－ｃ］ピリジン－２－オンのヘミ（Ｌ）－酒石酸塩形態及びそれを含む医薬組成物 |
| WO2022010882A1 (en) | 2020-07-07 | 2022-01-13 | Enanta Pharmaceuticals, Inc, | Dihydroquinoxaline and dihydropyridopyrazine derivatives as rsv inhibitors |
| WO2022086840A1 (en) | 2020-10-19 | 2022-04-28 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as anti-viral agents |
| US12612412B2 (en) | 2021-02-26 | 2026-04-28 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| MX2023009961A (es) | 2021-02-26 | 2023-09-05 | Enanta Pharm Inc | Compuestos heterociclicos antivirales. |
| AR129003A1 (es) | 2022-04-07 | 2024-07-03 | Enanta Pharm Inc | Compuestos heterocíclicos antivirales |
| WO2023211997A1 (en) | 2022-04-27 | 2023-11-02 | Enanta Pharmaceuticals, Inc. | Antiviral compounds |
| WO2024174953A1 (zh) * | 2023-02-21 | 2024-08-29 | 苏州隆博泰药业有限公司 | 苯并咪唑类衍生物及其医药用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0960102A1 (en) | 1996-07-08 | 1999-12-01 | Du Pont Pharmaceuticals Company | AMIDINOINDOLES, AMIDINOAZOLES, AND ANALOGS THEREOF AS INHIBITORS OF FACTOR Xa AND OF THROMBIN |
| WO2000020400A1 (en) | 1998-10-05 | 2000-04-13 | Axys Pharmaceuticals, Inc. | Novel compounds and compositions for treating hepatitis c infections |
| MXPA02000120A (es) | 1999-06-28 | 2002-07-02 | Janssen Pharmaceutica Nv | Inhibidores de la replicacion del virus sincitial respiratorio. |
| EP1418175A1 (en) | 1999-06-28 | 2004-05-12 | Janssen Pharmaceutica N.V. | Respiratory syncytial virus replication inhibitors |
| WO2001012600A1 (en) | 1999-08-12 | 2001-02-22 | Cor Therapeutics, Inc. | INHIBITORS OF FACTOR Xa |
| US6489338B2 (en) | 2000-06-13 | 2002-12-03 | Bristol-Myers Squibb Company | Imidazopyridine and imidazopyrimidine antiviral agents |
| US6506738B1 (en) | 2000-09-27 | 2003-01-14 | Bristol-Myers Squibb Company | Benzimidazolone antiviral agents |
| US6919331B2 (en) * | 2001-12-10 | 2005-07-19 | Bristol-Myers Squibb Company | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents |
| US20040166137A1 (en) | 2002-11-08 | 2004-08-26 | Lackey John William | Hetero-substituted benzimidazole compounds and antiviral uses thereof |
| TWI501967B (zh) | 2010-12-16 | 2015-10-01 | Janssen R&D Ireland | 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類 |
| TWI515187B (zh) | 2010-12-16 | 2016-01-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之吲哚類 |
| TWI541241B (zh) | 2010-12-16 | 2016-07-11 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類 |
| TWI527814B (zh) | 2010-12-16 | 2016-04-01 | 健生科學愛爾蘭無限公司 | 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類 |
| TWI530495B (zh) | 2010-12-16 | 2016-04-21 | 健生科學愛爾蘭無限公司 | 苯并咪唑呼吸道融合病毒抑制劑 |
-
2011
- 2011-12-15 TW TW100146390A patent/TWI530495B/zh not_active IP Right Cessation
- 2011-12-16 AU AU2011343255A patent/AU2011343255B2/en not_active Ceased
- 2011-12-16 WO PCT/EP2011/073008 patent/WO2012080446A1/en not_active Ceased
- 2011-12-16 KR KR1020137016944A patent/KR101876240B1/ko not_active Expired - Fee Related
- 2011-12-16 MY MYPI2013001281A patent/MY156641A/en unknown
- 2011-12-16 HU HUE11802054A patent/HUE029247T2/en unknown
- 2011-12-16 NZ NZ609450A patent/NZ609450A/en not_active IP Right Cessation
- 2011-12-16 AR ARP110104739A patent/AR085203A1/es active IP Right Grant
- 2011-12-16 EP EP11802054.4A patent/EP2651903B1/en active Active
- 2011-12-16 JP JP2013543799A patent/JP6005656B2/ja not_active Expired - Fee Related
- 2011-12-16 PL PL11802054.4T patent/PL2651903T3/pl unknown
- 2011-12-16 SG SG2013026711A patent/SG190766A1/en unknown
- 2011-12-16 PH PH1/2013/500796A patent/PH12013500796A1/en unknown
- 2011-12-16 CA CA2821999A patent/CA2821999C/en active Active
- 2011-12-16 DK DK11802054.4T patent/DK2651903T3/da active
- 2011-12-16 BR BR112013012137A patent/BR112013012137A2/pt not_active Application Discontinuation
- 2011-12-16 ES ES11802054.4T patent/ES2576180T3/es active Active
- 2011-12-16 CN CN201710103106.8A patent/CN107417683A/zh active Pending
- 2011-12-16 SI SI201130853A patent/SI2651903T1/sl unknown
- 2011-12-16 PT PT118020544T patent/PT2651903E/pt unknown
- 2011-12-16 EA EA201390888A patent/EA022972B1/ru not_active IP Right Cessation
- 2011-12-16 MX MX2013006886A patent/MX340030B/es active IP Right Grant
- 2011-12-16 HR HRP20160650TT patent/HRP20160650T1/hr unknown
- 2011-12-16 CN CN2011800602778A patent/CN103313974A/zh active Pending
- 2011-12-16 UA UAA201305027A patent/UA112298C2/uk unknown
- 2011-12-16 US US13/993,107 patent/US8865705B2/en active Active
-
2013
- 2013-04-09 IL IL225640A patent/IL225640A/en active IP Right Grant
- 2013-06-13 CL CL2013001713A patent/CL2013001713A1/es unknown
- 2013-06-14 ZA ZA2013/04424A patent/ZA201304424B/en unknown
-
2016
- 2016-06-22 CY CY20161100561T patent/CY1117751T1/el unknown
-
2018
- 2018-05-31 HK HK18107115.5A patent/HK1247616A1/zh unknown
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