|
ES2845212T3
(es)
|
2009-04-13 |
2021-07-26 |
Inst Nat Sante Rech Med |
Partículas de HPV y usos de las mismas
|
|
EP4282419A1
(en)
|
2012-12-20 |
2023-11-29 |
Purdue Research Foundation |
Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
|
|
US9573988B2
(en)
|
2013-02-20 |
2017-02-21 |
Novartis Ag |
Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells
|
|
LT2958943T
(lt)
|
2013-02-20 |
2020-01-27 |
The Trustees Of The University Of Pennsylvania |
Vėžio gydymas, naudojant humanizuotą anti-egfrviii chimerinio antigeno receptorių
|
|
EP2970426B1
(en)
|
2013-03-15 |
2019-08-28 |
Michael C. Milone |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
TWI654206B
(zh)
|
2013-03-16 |
2019-03-21 |
諾華公司 |
使用人類化抗-cd19嵌合抗原受體治療癌症
|
|
EP3974520A1
(en)
|
2013-05-14 |
2022-03-30 |
Board of Regents, The University of Texas System |
Human application of engineered chimeric antigen receptor (car) t-cells
|
|
EP4059521A1
(en)
|
2013-09-18 |
2022-09-21 |
Aura Biosciences, Inc. |
Virus-like particle conjugates for diagnosis and treatment of tumors
|
|
CA2931684C
(en)
|
2013-12-19 |
2024-02-20 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
|
EP3087101B1
(en)
|
2013-12-20 |
2024-06-05 |
Novartis AG |
Regulatable chimeric antigen receptor
|
|
WO2015112626A1
(en)
|
2014-01-21 |
2015-07-30 |
June Carl H |
Enhanced antigen presenting ability of car t cells by co-introduction of costimulatory molecules
|
|
US10441654B2
(en)
|
2014-01-24 |
2019-10-15 |
Children's Hospital Of Eastern Ontario Research Institute Inc. |
SMC combination therapy for the treatment of cancer
|
|
CA3190002A1
(en)
|
2014-02-14 |
2015-08-20 |
Board Of Regents, The University Of Texas System |
Chimeric antigen receptors and methods of making
|
|
EP3593812A3
(en)
|
2014-03-15 |
2020-05-27 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor
|
|
IL322264A
(en)
|
2014-04-07 |
2025-09-01 |
Novartis Ag |
Cancer treatment using chimeric antigen receptor (CAR) against CD19
|
|
AU2015243849B2
(en)
|
2014-04-10 |
2020-12-17 |
Seattle Children's Hospital (dba Seattle Children's Research Institute) |
Transgene genetic tags and methods of use
|
|
WO2015179801A1
(en)
|
2014-05-23 |
2015-11-26 |
University Of Florida Research Foundation, Inc. |
Car based immunotherapy
|
|
GB201506423D0
(en)
*
|
2015-04-15 |
2015-05-27 |
Tc Biopharm Ltd |
Gamma delta T cells and uses thereof
|
|
MY181834A
(en)
|
2014-07-21 |
2021-01-08 |
Novartis Ag |
Treatment of cancer using humanized anti-bcma chimeric antigen receptor
|
|
WO2016014530A1
(en)
*
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
JP6736540B2
(ja)
|
2014-07-21 |
2020-08-05 |
ノバルティス アーゲー |
Cll−1キメラ抗原受容体を使用した癌の処置
|
|
US9777061B2
(en)
|
2014-07-21 |
2017-10-03 |
Novartis Ag |
Treatment of cancer using a CD33 chimeric antigen receptor
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
SG11201700770PA
(en)
|
2014-08-19 |
2017-03-30 |
Novartis Ag |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
|
KR102387122B1
(ko)
*
|
2014-08-19 |
2022-04-14 |
밀테니 비오텍 비.브이. & 씨오. 케이지 |
Ssea4 항원에 특이적인 키메라 항원 수용체
|
|
ES2891332T3
(es)
|
2014-09-17 |
2022-01-27 |
Novartis Ag |
Direccionamiento a células citotóxicas con receptores quiméricos para la inmunoterapia adoptiva
|
|
AU2015330898B2
(en)
|
2014-10-08 |
2022-03-10 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
|
WO2016090190A1
(en)
|
2014-12-03 |
2016-06-09 |
Juno Therapeutics, Inc. |
Methods and compositions for adoptive cell therapy
|
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
|
CN113968912B
(zh)
|
2014-12-05 |
2025-05-16 |
纪念斯隆-凯特琳癌症中心 |
靶向g-蛋白偶联受体的嵌合抗原受体及其用途
|
|
WO2016090337A1
(en)
|
2014-12-05 |
2016-06-09 |
Memorial Sloan-Kettering Cancer Center |
Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof
|
|
SG11201704549UA
(en)
|
2014-12-05 |
2017-07-28 |
Memorial Sloan Kettering Cancer Center |
Chimeric antigen receptors targeting b-cell maturation antigen and uses thereof
|
|
KR102602417B1
(ko)
|
2014-12-05 |
2023-11-16 |
메모리얼 슬로안 케터링 캔서 센터 |
G-단백질 커플화 수용체를 표적화하는 항체 및 이의 사용 방법
|
|
EP3872094A3
(en)
|
2014-12-05 |
2021-12-08 |
Memorial Sloan Kettering Cancer Center |
Antibodies targeting b-cell maturation antigen and methods of use
|
|
US20190054117A1
(en)
*
|
2014-12-19 |
2019-02-21 |
Novartis Ag |
Dimerization switches and uses thereof
|
|
CN107567461A
(zh)
|
2014-12-29 |
2018-01-09 |
诺华股份有限公司 |
制备嵌合抗原受体表达细胞的方法
|
|
US11459390B2
(en)
|
2015-01-16 |
2022-10-04 |
Novartis Ag |
Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor
|
|
WO2016120218A1
(en)
|
2015-01-26 |
2016-08-04 |
Cellectis |
ANTI-CLL1 SPECIFIC SINGLE-CHAIN CHIMERIC ANTIGEN RECEPTORS (scCARS) FOR CANCER IMMUNOTHERAPY
|
|
US11161907B2
(en)
|
2015-02-02 |
2021-11-02 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
WO2016130598A1
(en)
|
2015-02-09 |
2016-08-18 |
University Of Florida Research Foundation, Inc. |
Bi-specific chimeric antigen receptor and uses thereof
|
|
WO2016134284A1
(en)
|
2015-02-19 |
2016-08-25 |
University Of Florida Research Foundation, Inc. |
Chimeric antigen receptors and uses thereof
|
|
EP3258967A4
(en)
|
2015-02-20 |
2018-10-03 |
Ohio State Innovation Foundation |
Bivalent antibody directed against nkg2d and tumor associated antigens
|
|
KR102133857B1
(ko)
|
2015-03-02 |
2020-07-20 |
이노베이티브 셀룰러 테라퓨틱스 코퍼레이션 리미티드 |
Pd-l1에 의해 유도된 면역관용의 감소
|
|
US9777064B2
(en)
|
2015-03-17 |
2017-10-03 |
Chimera Bioengineering, Inc. |
Smart CAR devices, DE CAR polypeptides, side CARs and uses thereof
|
|
CN106146666B
(zh)
*
|
2015-03-26 |
2019-09-06 |
科济生物医药(上海)有限公司 |
靶向cldn6的免疫效应细胞及其制备方法和应用
|
|
CN108367057B
(zh)
|
2015-04-06 |
2022-11-22 |
赛通免疫股份有限公司 |
用于胶质母细胞瘤的egfr导向的car疗法
|
|
MX2017012939A
(es)
|
2015-04-08 |
2018-05-22 |
Novartis Ag |
Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19.
|
|
AU2016249005B2
(en)
|
2015-04-17 |
2022-06-16 |
Novartis Ag |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
GB201507368D0
(en)
|
2015-04-30 |
2015-06-17 |
Ucl Business Plc |
Cell
|
|
BR112017024757A2
(pt)
|
2015-05-18 |
2018-11-13 |
TCR2 Therapeutics Inc. |
composições e métodos para reprogramação de tcr utilizando proteínas de fusão
|
|
MX383614B
(es)
|
2015-05-21 |
2025-03-14 |
Harpoon Therapeutics Inc |
Proteinas de union triespecificas y metodos de uso.
|
|
WO2017015427A1
(en)
|
2015-07-21 |
2017-01-26 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|
|
CN116064401A
(zh)
*
|
2015-07-29 |
2023-05-05 |
昂克医疗有限公司 |
具有增强的细胞毒性的修饰的天然杀伤细胞和天然杀伤细胞系
|
|
GB2557123B
(en)
|
2015-07-31 |
2021-11-03 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
US11667691B2
(en)
|
2015-08-07 |
2023-06-06 |
Novartis Ag |
Treatment of cancer using chimeric CD3 receptor proteins
|
|
JP7162530B2
(ja)
|
2015-08-07 |
2022-10-28 |
シアトル チルドレンズ ホスピタル (ディービーエイ シアトル チルドレンズ リサーチ インスティテュート) |
固形腫瘍を標的とする二重特異性car t細胞
|
|
GB201514874D0
(en)
|
2015-08-20 |
2015-10-07 |
Autolus Ltd |
Cell
|
|
WO2017040324A1
(en)
*
|
2015-08-28 |
2017-03-09 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for cells expressing a chimeric intracellular signaling molecule
|
|
CN116334205A
(zh)
|
2015-09-03 |
2023-06-27 |
诺华股份有限公司 |
预测细胞因子释放综合征的生物标志物
|
|
JP2018532990A
(ja)
|
2015-09-04 |
2018-11-08 |
オービーアイ ファーマ,インコーポレイテッド |
グリカンアレイおよび使用の方法
|
|
KR20180053744A
(ko)
|
2015-09-23 |
2018-05-23 |
사이토이뮨 테라퓨틱스 엘엘씨 |
면역 요법을 위한 flt3 유도된 car 세포
|
|
CN105567649A
(zh)
*
|
2015-10-26 |
2016-05-11 |
哈尔滨新联合生物科技有限公司 |
一种修饰的增强型dc-cik靶向免疫细胞群的制备方法和用途
|
|
EP3368075B1
(en)
*
|
2015-10-27 |
2020-01-29 |
Board of Regents, The University of Texas System |
Chimeric antigen receptor molecules and uses thereof
|
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
|
AU2016345681A1
(en)
|
2015-10-30 |
2018-05-10 |
Nbe-Therapeutics Ag |
Anti-ROR1 antibodies
|
|
WO2017075537A1
(en)
*
|
2015-10-30 |
2017-05-04 |
Aleta Biotherapeutics Inc. |
Compositions and methods for treatment of cancer
|
|
CN108473950A
(zh)
*
|
2015-10-30 |
2018-08-31 |
美国政府卫生与公众服务部 |
靶向癌症治疗
|
|
CN108472365A
(zh)
|
2015-10-30 |
2018-08-31 |
艾丽塔生物治疗剂公司 |
用于肿瘤转导的组合物和方法
|
|
CA3132021C
(en)
*
|
2015-11-18 |
2024-03-12 |
Merck Sharp & Dohme Corp. |
Pd1 and/or lag3 binders
|
|
JP2019500028A
(ja)
|
2015-11-19 |
2019-01-10 |
ブラッドセンター リサーチ ファウンデーション |
癌免疫療法で使用するための二重特異性t細胞を製造する方法
|
|
CN108884140B
(zh)
|
2015-12-03 |
2022-10-25 |
朱诺治疗学股份有限公司 |
修饰的嵌合受体及相关组合物和方法
|
|
CN108699557B
(zh)
|
2015-12-04 |
2025-08-15 |
诺华股份有限公司 |
用于免疫肿瘤学的组合物和方法
|
|
CN109071654B
(zh)
|
2015-12-04 |
2022-09-23 |
纪念斯隆-凯特琳癌症中心 |
靶向Fc受体样5的抗体及使用方法
|
|
US11052111B2
(en)
|
2015-12-08 |
2021-07-06 |
Chimera Bioengineering, Inc. |
Smart CAR devices and DE CAR polypeptides for treating disease and methods for enhancing immune responses
|
|
PT3393504T
(pt)
|
2015-12-22 |
2025-12-30 |
Novartis Ag |
Recetor de antigénio quimérico (car) de mesotelina e anticorpo contra o inibidor de pd-l1 para utilização combinada em terapia anticancerígena
|
|
CA3009852A1
(en)
|
2015-12-28 |
2017-07-06 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
BR112018013074A2
(en)
|
2015-12-30 |
2018-12-11 |
Novartis Ag |
immune effector cell therapies with enhanced efficacy
|
|
JP2019506155A
(ja)
|
2016-01-12 |
2019-03-07 |
クレッシェンド、バイオロジックス、リミテッドCrescendo Biologics Limited |
治療分子
|
|
EP3405496B1
(en)
|
2016-01-20 |
2023-10-25 |
University of Florida Research Foundation, Incorporated |
Ror1 antibody compositions and related methods
|
|
JOP20170017B1
(ar)
*
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
|
EP4086285A1
(en)
*
|
2016-02-25 |
2022-11-09 |
Cell Medica Switzerland AG |
Binding members to pd-l1
|
|
CA3016287A1
(en)
|
2016-03-04 |
2017-09-08 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
US11767362B1
(en)
*
|
2016-03-15 |
2023-09-26 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of treating cancers using PD-1 axis binding antagonists and anti-GPC3 antibodies
|
|
US12590321B2
(en)
|
2016-03-19 |
2026-03-31 |
Exuma Biotech Corp. |
Methods and compositions for genetically modifying and expanding lymphocytes and regulating the activity thereof
|
|
US11325948B2
(en)
|
2016-03-19 |
2022-05-10 |
Exuma Biotech Corp. |
Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
|
|
US11111505B2
(en)
|
2016-03-19 |
2021-09-07 |
Exuma Biotech, Corp. |
Methods and compositions for transducing lymphocytes and regulating the activity thereof
|
|
WO2017162797A1
(en)
*
|
2016-03-23 |
2017-09-28 |
Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Fusion proteins of pd-1 and 4-1bb
|
|
US11549099B2
(en)
|
2016-03-23 |
2023-01-10 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
|
US10980894B2
(en)
|
2016-03-29 |
2021-04-20 |
Obi Pharma, Inc. |
Antibodies, pharmaceutical compositions and methods
|
|
US11041017B2
(en)
|
2016-03-29 |
2021-06-22 |
Obi Pharma, Inc. |
Antibodies, pharmaceutical compositions and methods
|
|
WO2017172981A2
(en)
|
2016-03-29 |
2017-10-05 |
University Of Southern California |
Chimeric antigen receptors targeting cancer
|
|
US10689450B2
(en)
|
2016-04-01 |
2020-06-23 |
Kite Pharma, Inc |
BCMA binding molecules and methods of use thereof
|
|
US10654934B2
(en)
|
2016-04-01 |
2020-05-19 |
Innovative Cellular Therapeutics CO., LTD. |
Use of chimeric antigen receptor modified cells to treat cancer
|
|
KR102694879B1
(ko)
*
|
2016-04-01 |
2024-08-16 |
암젠 인크 |
Flt3에 대한 키메라 수용체 및 이의 사용 방법
|
|
US10603380B2
(en)
|
2016-04-01 |
2020-03-31 |
Kite Pharma, Inc. |
Chimeric antigen and T cell receptors and methods of use
|
|
KR102608405B1
(ko)
*
|
2016-04-01 |
2023-12-01 |
카이트 파마 인코포레이티드 |
키메라 수용체 및 그의 사용 방법
|
|
EP3436059B1
(en)
*
|
2016-04-01 |
2022-01-12 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Use of chimeric antigen receptor modified cells to treat cancer
|
|
CA3020330A1
(en)
*
|
2016-04-07 |
2017-10-12 |
Bluebird Bio, Inc. |
Chimeric antigen receptor t cell compositions
|
|
US12144850B2
(en)
|
2016-04-08 |
2024-11-19 |
Purdue Research Foundation |
Methods and compositions for car T cell therapy
|
|
JP6987390B2
(ja)
|
2016-04-08 |
2021-12-22 |
エモリー ユニバーシティー |
細胞ベースの治療法を用いて癌および感染性疾患を処置する方法
|
|
EP3443001B1
(en)
|
2016-04-11 |
2025-04-30 |
Obsidian Therapeutics, Inc. |
REGULATED BIOCIRCUIT SYSTEMS
|
|
ES2764805T3
(es)
*
|
2016-04-12 |
2020-06-04 |
Philogen Spa |
Terapia de combinación que comprende una inmunocitocina inflamatoria y una célula T con receptor de antígeno quimérico (CAR)
|
|
CN106399255B
(zh)
*
|
2016-04-13 |
2019-10-18 |
阿思科力(苏州)生物科技有限公司 |
Pd-1 car-t细胞及其制备方法和应用
|
|
EP3443096B1
(en)
|
2016-04-15 |
2023-03-01 |
Novartis AG |
Compositions and methods for selective expression of chimeric antigen receptors
|
|
CN105907719B
(zh)
*
|
2016-04-18 |
2019-10-18 |
阿思科力(苏州)生物科技有限公司 |
Anti ROBO1 CAR-T细胞及其制备和应用
|
|
KR20250048399A
(ko)
|
2016-04-22 |
2025-04-08 |
오비아이 파머 인코퍼레이티드 |
글로보 계열 항원을 통한 면역 활성화 또는 면역 조정에 의한 암 면역요법
|
|
WO2017190096A1
(en)
*
|
2016-04-29 |
2017-11-02 |
University Of Florida Research Foundation Incorporated |
Chimeric antigen receptors and uses thereof
|
|
GB201607968D0
(en)
*
|
2016-05-06 |
2016-06-22 |
Crescendo Biolog Ltd |
Chimeric antigen receptor
|
|
US10222369B2
(en)
|
2016-05-17 |
2019-03-05 |
Chimera Bioengineering, Inc. |
Methods for making novel antigen binding domains
|
|
US10100106B2
(en)
|
2016-05-20 |
2018-10-16 |
Harpoon Therapeutics, Inc. |
Single domain serum albumin binding protein
|
|
KR101926166B1
(ko)
*
|
2016-05-24 |
2018-12-06 |
재단법인 아산사회복지재단 |
수용체 시너지 활성을 이용한 nk 세포의 활성도 검사 방법 및 이를 이용한 nk 세포의 활성도가 관련된 질환의 진단 방법
|
|
MX389710B
(es)
|
2016-05-27 |
2025-03-20 |
Agenus Inc |
Anticuerpos anti proteina inmunoglobulina de linfocitos t y dominio de mucina 3 (tim-3) y métodos para usarlos.
|
|
CA3025516A1
(en)
|
2016-05-27 |
2017-11-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Flt3-specific chimeric antigen receptors and methods using same
|
|
US20210177896A1
(en)
|
2016-06-02 |
2021-06-17 |
Novartis Ag |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
|
EP3468994A1
(en)
|
2016-06-08 |
2019-04-17 |
Intrexon Corporation |
Cd33 specific chimeric antigen receptors
|
|
US11472856B2
(en)
|
2016-06-13 |
2022-10-18 |
Torque Therapeutics, Inc. |
Methods and compositions for promoting immune cell function
|
|
WO2018012895A1
(ko)
*
|
2016-07-14 |
2018-01-18 |
주식회사 큐로셀 |
면역관문을 극복한 면역세포 및 상기 면역세포를 포함한 약제학적 조성물
|
|
CA3030429A1
(en)
|
2016-07-14 |
2018-01-18 |
Mingsight Pharmaceuticals, Inc. |
Treatment of cancer
|
|
SG11201900344YA
(en)
|
2016-07-15 |
2019-02-27 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
|
CN106220736B
(zh)
*
|
2016-07-20 |
2020-01-10 |
深圳市体内生物医药科技有限公司 |
一种嵌合抗原受体、表达其的细胞及其制备方法和用途
|
|
AU2017301826A1
(en)
*
|
2016-07-26 |
2019-03-14 |
Tessa Therapeutics Ltd. |
Chimeric antigen receptor
|
|
WO2018022933A1
(en)
|
2016-07-27 |
2018-02-01 |
Obi Pharma, Inc. |
Immunogenic/therapeutic glycan compositions and uses thereof
|
|
CN110214150A
(zh)
|
2016-07-28 |
2019-09-06 |
诺华股份有限公司 |
嵌合抗原受体和pd-1抑制剂的组合疗法
|
|
EP3491026A4
(en)
|
2016-07-29 |
2020-07-29 |
OBI Pharma, Inc. |
HUMAN ANTIBODIES, PHARMACEUTICAL COMPOSITIONS AND PROCESSES
|
|
EP3490590A2
(en)
|
2016-08-01 |
2019-06-05 |
Novartis AG |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
|
WO2018026953A1
(en)
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
CA3032838A1
(en)
*
|
2016-08-04 |
2018-02-08 |
Memorial Sloan-Kettering Cancer Center |
Compositions and methods for immunotherapy
|
|
AU2017307610B2
(en)
|
2016-08-04 |
2023-10-05 |
Memorial Sloan-Kettering Cancer Center |
Cancer antigen targets and uses thereof
|
|
KR102512934B1
(ko)
*
|
2016-08-10 |
2023-03-23 |
레전드 바이오테크 아일랜드 리미티드 |
Bcma를 표적으로 하는 키메라 항원 수용체 및 이들의 이용 방법
|
|
JP7215808B2
(ja)
*
|
2016-08-12 |
2023-01-31 |
ツールゲン インコーポレイテッド |
操作された免疫調節エレメントおよび変更された免疫
|
|
CA3033876A1
(en)
*
|
2016-08-18 |
2018-02-22 |
The Uab Research Foundation |
Compositions and methods for cancer immunotherapy
|
|
WO2018045034A1
(en)
*
|
2016-08-30 |
2018-03-08 |
Promab Biotechnologies, Inc. |
Chimeric antigen receptors having gitr intracellular domain as co-stimulatory domain
|
|
EP4342978A3
(en)
|
2016-09-01 |
2024-07-03 |
Chimera Bioengineering Inc. |
Gold optimized car t-cells
|
|
CN107793482A
(zh)
*
|
2016-09-06 |
2018-03-13 |
广州百尼夫生物科技有限公司 |
嵌合抗原受体及其基因和重组表达载体、car133‑nkt 细胞及其制备方法和应用
|
|
US20190262399A1
(en)
|
2016-09-07 |
2019-08-29 |
The Broad Institute, Inc. |
Compositions and methods for evaluating and modulating immune responses
|
|
EP3510156A1
(en)
*
|
2016-09-08 |
2019-07-17 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods of treating cancer
|
|
CN106434563B
(zh)
*
|
2016-09-14 |
2017-09-22 |
深圳市默赛尔生物医学科技发展有限公司 |
转基因自然杀伤细胞及其制备方法和应用
|
|
CA3039406A1
(en)
|
2016-09-19 |
2018-03-22 |
University Of Southern California |
Non-radioactive cytotoxicity assays
|
|
EP3515503B1
(en)
|
2016-09-23 |
2025-10-29 |
The Regents Of The University Of Michigan |
Engineered lymphocytes
|
|
CN107868791B
(zh)
*
|
2016-09-26 |
2021-11-23 |
阿思科力(苏州)生物科技有限公司 |
一种加强型Slit2 CAR-T和CAR-NK细胞制备方法和应用
|
|
WO2018064387A1
(en)
|
2016-09-28 |
2018-04-05 |
Novartis Ag |
Porous membrane-based macromolecule delivery system
|
|
CN106317228A
(zh)
*
|
2016-09-28 |
2017-01-11 |
李华顺 |
一种嵌合抗原受体分子及其应用
|
|
EP3519562A4
(en)
*
|
2016-09-29 |
2020-03-25 |
Nantkwest, Inc. |
NK-92 HLA CLASS I DEFICIENT CELLS WITH REDUCED IMMUNOGENICITY
|
|
US20190119636A1
(en)
|
2017-10-23 |
2019-04-25 |
Poseida Therapeutics, Inc. |
Modified stem cell memory t cells, methods of making and methods of using same
|
|
CA3105873A1
(en)
*
|
2016-09-30 |
2018-04-05 |
Poseida Therapeutics, Inc. |
Modified stem cell memory t cells, methods of making and methods of using same
|
|
WO2018064921A1
(en)
*
|
2016-10-06 |
2018-04-12 |
Innovative Cellular Therapeutics CO., LTD. |
Use of chimeric antigen receptor modified cells to treat cancer
|
|
WO2018067992A1
(en)
|
2016-10-07 |
2018-04-12 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
MX2019003899A
(es)
|
2016-10-07 |
2019-08-14 |
Tcr2 Therapeutics Inc |
Composiciones y metodos para reprogramacion de receptores de linfocitos t mediante el uso de proteinas de fusion.
|
|
US12098202B2
(en)
*
|
2016-10-10 |
2024-09-24 |
The National Institute for Biotechnology in the Negev Ltd. |
Non-cytotoxic modified cells and use thereof
|
|
KR102576042B1
(ko)
|
2016-10-11 |
2023-09-07 |
아게누스 인코포레이티드 |
항-lag-3 항체 및 이의 사용 방법
|
|
ES2939646T3
(es)
|
2016-10-13 |
2023-04-25 |
Juno Therapeutics Inc |
Métodos y composiciones de inmunoterapia que comprenden moduladores de la vía metabólica del triptófano
|
|
GB2573406B
(en)
|
2016-10-18 |
2021-11-10 |
Univ Minnesota |
Tumor infiltrating lymphocytes and methods of therapy
|
|
EP3529353A4
(en)
|
2016-10-19 |
2020-05-13 |
City of Hope |
USE OF TRIPLEX-CMV VACCINE IN CAR-T-CELL THERAPY
|
|
CN107988164B
(zh)
|
2016-10-26 |
2020-07-07 |
阿思科力(苏州)生物科技有限公司 |
一种pd-1 car nk-92细胞及其制备方法与应用
|
|
CN106591363A
(zh)
*
|
2016-11-11 |
2017-04-26 |
广东万海细胞生物科技有限公司 |
一种通用型异体car‑t细胞制备方法及应用
|
|
US11332713B2
(en)
|
2016-11-16 |
2022-05-17 |
KSQ Therapeutics, Inc. |
Gene-regulating compositions and methods for improved immunotherapy
|
|
AU2017363311A1
(en)
|
2016-11-22 |
2019-06-13 |
TCR2 Therapeutics Inc. |
Compositions and methods for TCR reprogramming using fusion proteins
|
|
JP7685735B2
(ja)
|
2016-12-02 |
2025-05-30 |
アンヘレス セラピューティクス インコーポレイテッド |
合成免疫受容体およびその使用方法
|
|
MA46995A
(fr)
|
2016-12-03 |
2019-10-09 |
Acerta Pharma Bv |
Méthodes et compositions pour l'utilisation de lymphocytes t thérapeutiques en association avec des inhibiteurs de kinase
|
|
US20190358262A1
(en)
*
|
2016-12-03 |
2019-11-28 |
Juno Therapeutics, Inc. |
Methods for modulation of car-t cells
|
|
CN106701827A
(zh)
*
|
2016-12-05 |
2017-05-24 |
刘晓明 |
表达cd19和cd20抗体基因嵌合抗原受体t细胞的转化及扩增培养与保存方法
|
|
AU2017372856B9
(en)
*
|
2016-12-05 |
2024-01-04 |
Pharmacosmos Holding A/S |
Preservation of immune response during chemotherapy regimens
|
|
ES2875005T3
(es)
|
2016-12-09 |
2021-11-08 |
Onk Therapeutics Ltd |
Células asesinas naturales manipuladas y usos de las mismas
|
|
US11408005B2
(en)
|
2016-12-12 |
2022-08-09 |
Seattle Children's Hospital |
Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
|
|
WO2018111340A1
(en)
|
2016-12-16 |
2018-06-21 |
Novartis Ag |
Methods for determining potency and proliferative function of chimeric antigen receptor (car)-t cells
|
|
CN108204958A
(zh)
*
|
2016-12-19 |
2018-06-26 |
伊缪泰普有限公司 |
结合测定
|
|
JP2020513754A
(ja)
*
|
2016-12-21 |
2020-05-21 |
ティーシーアール2 セラピューティクス インク. |
がん治療用に操作されたt細胞
|
|
KR102760578B1
(ko)
|
2016-12-22 |
2025-02-03 |
큐 바이오파마, 인크. |
T-세포 조절 다량체 폴리펩타이드 및 이의 사용 방법
|
|
JP2020501589A
(ja)
*
|
2016-12-23 |
2020-01-23 |
ウイルツ・バイオロジクス・リミテッド |
がんの治療
|
|
CN110121505B
(zh)
|
2016-12-28 |
2023-08-01 |
株式会社绿十字细胞治疗 |
嵌合抗原受体和表达其的自然杀伤细胞
|
|
CN107286246B
(zh)
*
|
2016-12-28 |
2019-12-17 |
时力生物科技(北京)有限公司 |
治疗脑胶质瘤的嵌合抗原受体修饰的树突状细胞及其制备方法
|
|
CN108276493B
(zh)
*
|
2016-12-30 |
2023-11-14 |
南京传奇生物科技有限公司 |
一种嵌合抗原受体及其应用
|
|
JP7267921B2
(ja)
|
2017-01-06 |
2023-05-02 |
クレシェンド・バイオロジックス・リミテッド |
プログラム細胞死(pd-1)に対するシングルドメイン抗体
|
|
CA3049652A1
(en)
|
2017-01-10 |
2018-07-19 |
Intrexon Corporation |
Modulating expression of polypeptides via new gene switch expression systems
|
|
JP7303749B2
(ja)
*
|
2017-01-13 |
2023-07-05 |
セルダラ メディカル、エルエルシー |
Tim-1を標的とするキメラ抗原受容体
|
|
EP3572428A4
(en)
|
2017-01-17 |
2020-12-30 |
Daiichi Sankyo Company, Limited |
ANTI-BODY ANTI-GPR20 AND ANTI-BODY-DRUG CONJUGATE ANTI-GPR20
|
|
US20190350980A1
(en)
*
|
2017-01-18 |
2019-11-21 |
Drk Blutspendedienst Baden-W?Rttemberg-Hessen Gmbh |
Compositions and methods for transplant recipient conditioning
|
|
CN108330133B
(zh)
*
|
2017-01-20 |
2020-06-30 |
上海恒润达生生物科技有限公司 |
靶向cd19嵌合抗原受体并对其双重修饰的方法及其用途
|
|
EP3574005B1
(en)
|
2017-01-26 |
2021-12-15 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
|
JP2020506700A
(ja)
*
|
2017-01-31 |
2020-03-05 |
ノバルティス アーゲー |
多重特異性を有するキメラt細胞受容体タンパク質を用いた癌の治療
|
|
CN108395478A
(zh)
*
|
2017-02-04 |
2018-08-14 |
上海恒润达生生物科技有限公司 |
靶向bcma的嵌合抗原受体并对其双重修饰的方法及其用途
|
|
RU2019128134A
(ru)
*
|
2017-02-07 |
2021-03-09 |
Дайити Санкио Компани, Лимитед |
Антитело против gprc5d и молекула, содержащая антитело
|
|
CN108456250B
(zh)
*
|
2017-02-17 |
2025-11-28 |
恺兴生命科技(上海)有限公司 |
靶向il-13ra2的抗体及其应用
|
|
JP2020507605A
(ja)
|
2017-02-17 |
2020-03-12 |
フレッド ハッチンソン キャンサー リサーチ センター |
Bcma関連癌および自己免疫疾患の治療のための併用療法
|
|
EP3568469A4
(en)
*
|
2017-02-21 |
2020-11-11 |
Eutilex Co., Ltd. |
COMPOSITIONS OF CAR-T CELLS DIRECTED AGAINST HLA-DR AND THEIR MANUFACTURING AND USE PROCEDURES
|
|
IL269203B2
(en)
*
|
2017-03-13 |
2024-09-01 |
Poseida Therapeutics Inc |
Compositions and methods for selective elimination and replacement of hematopoietic stem cells
|
|
WO2018169922A2
(en)
|
2017-03-13 |
2018-09-20 |
Kite Pharma, Inc. |
Chimeric antigen receptors for melanoma and uses thereof
|
|
WO2018175473A1
(en)
*
|
2017-03-20 |
2018-09-27 |
University Of Southern California |
Adoptive transfer of car t cells with surface-conjugated drug-loaded nanoparticles and uses thereof
|
|
KR20190130608A
(ko)
|
2017-03-22 |
2019-11-22 |
노파르티스 아게 |
면역종양학을 위한 조성물 및 방법
|
|
CN107271675B
(zh)
*
|
2017-03-24 |
2020-06-02 |
郑猛 |
抗人adrb3单克隆抗体及其在疾病诊断和治疗中的应用
|
|
IL269531B2
(en)
|
2017-03-27 |
2024-10-01 |
Hoffmann La Roche |
Improved antigen binding receptors
|
|
US11963966B2
(en)
|
2017-03-31 |
2024-04-23 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
|
US11913075B2
(en)
|
2017-04-01 |
2024-02-27 |
The Broad Institute, Inc. |
Methods and compositions for detecting and modulating an immunotherapy resistance gene signature in cancer
|
|
CA3059882A1
(en)
|
2017-04-12 |
2018-10-18 |
Aura Biosciences, Inc. |
Targeted combination therapy
|
|
US20200071773A1
(en)
|
2017-04-12 |
2020-03-05 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
|
US11344578B2
(en)
|
2017-04-19 |
2022-05-31 |
Board Of Regents, The University Of Texas System |
Immune cells expressing engineered antigen receptors
|
|
PT3615146T
(pt)
|
2017-04-24 |
2023-11-27 |
Kite Pharma Inc |
Domínios de ligação ao antigénio humanizados contra cd19 e métodos de utilização
|
|
IL270138B2
(en)
|
2017-04-26 |
2025-08-01 |
Eureka Therapeutics Inc |
Structures that specifically recognize glypican 3 and their uses
|
|
CN109797171A
(zh)
*
|
2017-05-08 |
2019-05-24 |
北京东方略细胞技术有限公司 |
经修饰的t细胞、其制备方法及用途
|
|
CN110914431B
(zh)
|
2017-05-08 |
2024-04-19 |
株式会社图尔金 |
经人工操纵的免疫细胞
|
|
WO2018209324A2
(en)
|
2017-05-11 |
2018-11-15 |
The Broad Institute, Inc. |
Methods and compositions of use of cd8+ tumor infiltrating lymphocyte subtypes and gene signatures thereof
|
|
US11166985B2
(en)
|
2017-05-12 |
2021-11-09 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
|
BR112019023608A2
(pt)
|
2017-05-12 |
2020-05-26 |
Crispr Therapeutics Ag |
Materiais e métodos para células manipuladas e seus usos em imuno-oncologia
|
|
AU2018269370B2
(en)
|
2017-05-16 |
2025-06-05 |
The Johns Hopkins University |
Manabodies and methods of using
|
|
WO2018210279A1
(zh)
*
|
2017-05-16 |
2018-11-22 |
科济生物医药(上海)有限公司 |
Toll样受体激动剂与免疫效应细胞的联用
|
|
CA3065402A1
(en)
*
|
2017-05-31 |
2018-12-06 |
Carsgen Therapeutics Co., Ltd. |
Compositions and methods of cellular immunotherapy
|
|
JP2020521479A
(ja)
*
|
2017-06-01 |
2020-07-27 |
イノベイティブ セルラー セラピューティクス シーオー.,エルティディ.Innovative Cellular Therapeutics Co.,Ltd. |
キメラ抗原受容体細胞の作製及びその使用
|
|
PE20241587A1
(es)
|
2017-06-02 |
2024-08-01 |
Pfizer |
Receptores de antigenos quimericos que se dirigen a flt3
|
|
CN108977453A
(zh)
|
2017-06-02 |
2018-12-11 |
阿思科力(苏州)生物科技有限公司 |
一种以robo1为靶点的嵌合抗原受体细胞及其制备和应用
|
|
CN111225675B
(zh)
|
2017-06-02 |
2024-05-03 |
朱诺治疗学股份有限公司 |
使用过继细胞疗法治疗的制品和方法
|
|
CN110799640B
(zh)
*
|
2017-06-07 |
2024-11-12 |
综合医院公司 |
表达嵌合抗原受体的t细胞
|
|
US20200179450A1
(en)
*
|
2017-06-12 |
2020-06-11 |
Emory University |
T-cell antigen targeted chimeric antigen receptor (car) and uses in cell therapies
|
|
WO2018232195A1
(en)
|
2017-06-14 |
2018-12-20 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
CN109134660B
(zh)
*
|
2017-06-16 |
2022-07-01 |
上海恒润达生生物科技股份有限公司 |
靶向Mesothelin的嵌合抗原受体并联合表达抗PD1抗体的方法及其用途
|
|
KR20200019231A
(ko)
*
|
2017-06-22 |
2020-02-21 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
조절 면역 세포를 제조하기 위한 방법 및 이의 용도
|
|
CA3067914A1
(en)
|
2017-06-30 |
2019-01-03 |
Cellectis |
Cellular immunotherapy for repetitive administration
|
|
JP2020530307A
(ja)
|
2017-06-30 |
2020-10-22 |
インティマ・バイオサイエンス,インコーポレーテッド |
遺伝子治療のためのアデノ随伴ウイルスベクター
|
|
CN107164412B
(zh)
*
|
2017-06-30 |
2020-10-23 |
山东兴瑞生物科技有限公司 |
一种安全型抗cea嵌合抗原受体修饰t细胞的制备方法及其应用
|
|
GB201711068D0
(en)
|
2017-07-10 |
2017-08-23 |
Crescendo Biologics Ltd |
Therapeutic molecules binding PSMA
|
|
CN109232742B
(zh)
*
|
2017-07-11 |
2021-10-22 |
深圳市第二人民医院 |
一种嵌合抗原受体及其应用
|
|
US12049643B2
(en)
|
2017-07-14 |
2024-07-30 |
The Broad Institute, Inc. |
Methods and compositions for modulating cytotoxic lymphocyte activity
|
|
CN107353325B
(zh)
*
|
2017-07-26 |
2020-08-11 |
中国药科大学 |
叶酸受体α特异性结合肽1及其应用
|
|
CN107326014B
(zh)
*
|
2017-07-31 |
2019-09-24 |
时力生物科技(北京)有限公司 |
一种双特异性嵌合抗原受体修饰的t淋巴细胞及其制备方法和应用
|
|
KR20230008269A
(ko)
|
2017-08-07 |
2023-01-13 |
엔비이-테라퓨틱스 아게 |
생체 내 내성이 높은 항체 약물 결합체
|
|
CN111511762B
(zh)
*
|
2017-08-21 |
2025-05-06 |
天演药业公司 |
抗cd137分子及其用途
|
|
JP7248578B2
(ja)
|
2017-08-31 |
2023-03-29 |
第一三共株式会社 |
抗体-薬物コンジュゲートの新規製造方法
|
|
KR20250084239A
(ko)
|
2017-08-31 |
2025-06-10 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 콘주게이트의 개량 제조 방법
|
|
KR20210032924A
(ko)
|
2017-09-05 |
2021-03-25 |
토크 테라퓨틱스, 인코포레이티드 |
치료용 단백질 조성물 및 그의 제조 및 사용 방법
|
|
WO2019051135A1
(en)
|
2017-09-06 |
2019-03-14 |
Fred Hutchinson Cancer Research Center |
METHODS FOR IMPROVING ADOPTIVE CELL THERAPY
|
|
KR102521245B1
(ko)
*
|
2017-09-15 |
2023-04-17 |
카이트 파마 인코포레이티드 |
관리 연속성 및 신원 연속성 생물학적 샘플 추적으로 환자-특이적 면역요법 절차를 수행하기 위한 방법 및 시스템
|
|
BR112020005938A2
(pt)
|
2017-09-27 |
2020-11-17 |
University Of Southern California |
célula imune ou população de células imunes da mesma, célula efetora imune ou célula-tronco, célula que apresenta antígeno, polinucleotídeo recombinante, vetor, composição que compreende uma célula imune efetora ou uma célula-tronco, métodos para produzir uma célula efetora imune que expressa receptor imune de ocorrência não natural, para gerar uma população de células manipuladas por rna, para fornecer imunidade antidoença em um indivíduo, para tratar ou prevenir uma doença associada à expressão de um antígeno, e, uso
|
|
US12065498B2
(en)
|
2017-09-29 |
2024-08-20 |
Cell Design Labs, Inc. |
Methods of making bispecific anti-CD307E and anti-BCMA chimeric antigen receptors and uses of the same
|
|
CN107557341B
(zh)
*
|
2017-09-30 |
2020-06-30 |
山东兴瑞生物科技有限公司 |
一种抗wt1增强型嵌合抗原受体修饰的免疫细胞及其应用
|
|
WO2019070755A1
(en)
|
2017-10-02 |
2019-04-11 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING A GENETIC SIGNATURE OF IMMUNOTHERAPY RESISTANCE IN CANCER
|
|
US12467050B2
(en)
*
|
2017-10-02 |
2025-11-11 |
Georgia Tech Research Corporation |
Methods and compositions for engineering synthetic bioswitches for remote control of biological activity
|
|
KR20200063215A
(ko)
*
|
2017-10-06 |
2020-06-04 |
오슬로 유니버시테시케후스 에이치에프 |
키메라 항원 수용체
|
|
JP7227630B2
(ja)
*
|
2017-10-12 |
2023-02-22 |
マックマスター ユニバーシティー |
Y182t突然変異を有するt細胞-抗原カプラおよびその方法ならびに使用
|
|
SI3694529T1
(sl)
|
2017-10-13 |
2024-10-30 |
Harpoon Therapeutics, Inc. |
Trispecifične beljakovine in načini uporabe
|
|
IL315737A
(en)
|
2017-10-13 |
2024-11-01 |
Harpoon Therapeutics Inc |
B-cell maturation antigen-binding proteins
|
|
KR20200086278A
(ko)
|
2017-10-18 |
2020-07-16 |
노파르티스 아게 |
선택적 단백질 분해를 위한 조성물 및 방법
|
|
EP3697435A1
(en)
*
|
2017-10-20 |
2020-08-26 |
Fred Hutchinson Cancer Research Center |
Compositions and methods of immunotherapy targeting tigit and/or cd112r or comprising cd226 overexpression
|
|
WO2019084288A1
(en)
|
2017-10-25 |
2019-05-02 |
Novartis Ag |
METHODS FOR DESIGNING CHIMERIC ANTIGENIC RECEPTOR EXPRESSION CELLS
|
|
MX2020004572A
(es)
|
2017-11-01 |
2020-10-07 |
Juno Therapeutics Inc |
Receptores de antigenos quimericos especificos para el antigeno de maduracion de celulas b y polinucleotidos que codifican los mismos.
|
|
CA3080904A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Antibodies and chimeric antigen receptors specific for b-cell maturation antigen
|
|
EP3706754A1
(en)
|
2017-11-06 |
2020-09-16 |
Juno Therapeutics, Inc. |
Combination of a cell therapy and a gamma secretase inhibitor
|
|
WO2019094955A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for targeting developmental and oncogenic programs in h3k27m gliomas
|
|
CA3082297A1
(en)
|
2017-11-13 |
2019-05-16 |
Crescendo Biologics Limited |
Molecules that bind to cd137 and psma
|
|
EP3710039A4
(en)
|
2017-11-13 |
2021-08-04 |
The Broad Institute, Inc. |
METHODS AND COMPOSITIONS FOR TREATMENT OF CANCER BY TARGETING THE CLEC2D-KLRB1 PATH
|
|
EP3712178A4
(en)
|
2017-11-14 |
2021-08-11 |
Green Cross Lab Cell Corporation |
ANTI-HER2 ANTIBODIES OR ANTIGIBODY FRAGMENT THEREOF AND CHIMERAIR ANTIGEN RECEPTOR WITH IT
|
|
US11649294B2
(en)
|
2017-11-14 |
2023-05-16 |
GC Cell Corporation |
Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
|
|
WO2019099707A1
(en)
|
2017-11-16 |
2019-05-23 |
Kite Pharma, Inc |
Modified chimeric antigen receptors and methods of use
|
|
CN107916269B
(zh)
*
|
2017-11-17 |
2020-12-11 |
山东兴瑞生物科技有限公司 |
靶向cd19的tcr基因、制备方法、具有该基因的质粒、试剂盒及应用
|
|
CN121591910A
(zh)
*
|
2017-11-21 |
2026-03-03 |
诺华股份有限公司 |
针对肿瘤相关抗原的三特异性结合分子及其用途
|
|
US11944644B2
(en)
|
2017-12-05 |
2024-04-02 |
The Medical Research Infrastructure And Health Services Fund Of The Tel Aviv Medical Center |
T-cells comprising anti-CD38 and anti-CD138 chimeric antigen receptors and uses thereof
|
|
IL275040B2
(en)
*
|
2017-12-05 |
2026-05-01 |
The Medical Res Infrastructure And Health Services Fund Of The Tel Aviv Medical Center |
T cells containing two chimeric receptors for different antigens and their use
|
|
SG11202005307RA
(en)
*
|
2017-12-14 |
2020-07-29 |
Bluebird Bio Inc |
Nkg2d daric receptors
|
|
CA3086187A1
(en)
|
2017-12-20 |
2019-06-27 |
Poseida Therapeutics, Inc. |
Vcar compositions and methods for use
|
|
KR20250048610A
(ko)
|
2017-12-22 |
2025-04-09 |
페이트 세러퓨틱스, 인코포레이티드 |
향상된 면역 효과기 세포 및 이의 용도
|
|
CN109609533B
(zh)
*
|
2017-12-27 |
2020-07-10 |
赛德特生物科技开发有限公司 |
基于人源化cd276抗体的car慢病毒表达载体构建及其应用
|
|
CN109971712B
(zh)
*
|
2017-12-28 |
2023-06-20 |
上海细胞治疗研究院 |
特异性靶向cd19抗原且高水平稳定表达pd-1抗体的car-t细胞及用途
|
|
CN109971722B
(zh)
*
|
2017-12-28 |
2023-09-01 |
上海细胞治疗研究院 |
靶向cd19且高水平稳定表达cd40抗体的car-t细胞及其用途
|
|
AU2018395272A1
(en)
*
|
2017-12-28 |
2020-07-09 |
NEUGATE PHARMA, LLC aka NEUGATE THERANOSTICS |
Compositions and formulations for treatment of malignancies
|
|
CN109971715A
(zh)
*
|
2017-12-28 |
2019-07-05 |
深圳华大生命科学研究院 |
一种扩增特异性car-t细胞的培养方法
|
|
KR20200108275A
(ko)
|
2017-12-28 |
2020-09-17 |
코디악 바이오사이언시즈, 인크. |
면역-종양학 및 항-염증 요법을 위한 엑소좀
|
|
CN108103105A
(zh)
*
|
2017-12-29 |
2018-06-01 |
深圳市茵冠生物科技有限公司 |
一种car-t细胞的制备方法、制得的car-t细胞及其应用
|
|
CA3086832A1
(en)
|
2018-01-03 |
2019-07-11 |
Qu Biologics Inc. |
Innate targeting of adoptive cellular therapies
|
|
US11994512B2
(en)
|
2018-01-04 |
2024-05-28 |
Massachusetts Institute Of Technology |
Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
|
|
EP3508855A1
(en)
*
|
2018-01-05 |
2019-07-10 |
Allianz Pharmascience Ltd |
Method for the selection of patients and kit
|
|
CN112218651A
(zh)
*
|
2018-01-08 |
2021-01-12 |
诺华公司 |
用于与嵌合抗原受体疗法组合的免疫增强rna
|
|
WO2019139987A1
(en)
|
2018-01-09 |
2019-07-18 |
Elstar Therapeutics, Inc. |
Calreticulin binding constructs and engineered t cells for the treatment of diseases
|
|
US11951129B2
(en)
|
2018-01-09 |
2024-04-09 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Compositions and methods for targeting CLEC12A-expressing cancers
|
|
US10561686B2
(en)
*
|
2018-01-12 |
2020-02-18 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
|
EP4006153B1
(en)
*
|
2018-01-12 |
2024-07-03 |
Curocell Inc. |
Enhanced immune cells using dual shrna and composition including the same
|
|
US20210069194A1
(en)
*
|
2018-01-17 |
2021-03-11 |
Mingsight Pharmaceuticals, Inc. |
Combination therapy for the treatment of cancer
|
|
CA3088832A1
(en)
|
2018-01-19 |
2019-07-25 |
Miltenyi Biotec B.V. & Co. KG |
Regulatory t cell expressing a chimeric antigen receptor
|
|
US11311576B2
(en)
|
2018-01-22 |
2022-04-26 |
Seattle Children's Hospital |
Methods of use for CAR T cells
|
|
CN110093351B
(zh)
*
|
2018-01-29 |
2023-06-23 |
华南生物医药研究院 |
可分离的核酸、多肽、重组载体、重组细胞及应用
|
|
AU2019215031C1
(en)
*
|
2018-01-31 |
2026-02-26 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
CN111989108B
(zh)
|
2018-02-13 |
2024-07-16 |
嵌合体生物工程公司 |
利用rna去稳定元件协调基因表达
|
|
JP2021513839A
(ja)
|
2018-02-16 |
2021-06-03 |
カイト ファーマ インコーポレイテッドKite Pharma, Inc |
改変された多能性幹細胞並びに製造方法及び使用方法
|
|
GB201802573D0
(en)
|
2018-02-16 |
2018-04-04 |
Crescendo Biologics Ltd |
Therapeutic molecules that bind to LAG3
|
|
WO2019165121A1
(en)
|
2018-02-21 |
2019-08-29 |
Board Of Regents, The University Of Texas System |
Methods for activation and expansion of natural killer cells and uses therof
|
|
CA3091674A1
(en)
*
|
2018-02-23 |
2019-08-29 |
Endocyte, Inc. |
Sequencing method for car t cell therapy
|
|
WO2019173324A1
(en)
|
2018-03-06 |
2019-09-12 |
The Trustees Of The University Of Pennsylvania |
Prostate-specific membrane antigen cars and methods of use thereof
|
|
KR20210013013A
(ko)
*
|
2018-03-09 |
2021-02-03 |
카르스젠 테라퓨틱스 리미티드 |
종양 치료 방법 및 조성물
|
|
WO2019175328A1
(en)
|
2018-03-14 |
2019-09-19 |
Imba - Institut Für Molekulare Biotechnologie Gmbh |
Bh4pathwayactivationandusethereoffortreatingcancer
|
|
WO2019178420A1
(en)
|
2018-03-15 |
2019-09-19 |
KSQ Therapeutics, Inc. |
Gene-regulating compositions and methods for improved immunotherapy
|
|
US20190284553A1
(en)
|
2018-03-15 |
2019-09-19 |
KSQ Therapeutics, Inc. |
Gene-regulating compositions and methods for improved immunotherapy
|
|
EP3768700A1
(en)
|
2018-03-23 |
2021-01-27 |
Kite Pharma, Inc. |
Chimeric transmembrane proteins and uses thereof
|
|
US10688182B2
(en)
*
|
2018-03-29 |
2020-06-23 |
Cho Pharma Usa, Inc. |
Monoclonal antibodies that bind to SSEA4 and uses thereof
|
|
WO2019192972A1
(en)
*
|
2018-04-04 |
2019-10-10 |
F. Hoffmann-La Roche Ag |
Diagnostic assays to detect tumor antigens in cancer patients
|
|
WO2019195583A1
(en)
*
|
2018-04-06 |
2019-10-10 |
Mustang Bio, Inc. |
Manufacturing methods for cell-based therapeutic compositions
|
|
CN112262214A
(zh)
|
2018-04-12 |
2021-01-22 |
优莫佳生物制药股份有限公司 |
病毒载体及包装细胞系
|
|
US10869888B2
(en)
|
2018-04-17 |
2020-12-22 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expansion and uses thereof
|
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
|
US12201659B2
(en)
|
2018-04-27 |
2025-01-21 |
Mayo Foundation For Medical Education And Research |
Foamy viruses and methods of use
|
|
CN112752767A
(zh)
*
|
2018-04-27 |
2021-05-04 |
克里斯珀医疗股份公司 |
细胞毒性t细胞耗竭的方法和组合物
|
|
US20210094994A1
(en)
*
|
2018-04-27 |
2021-04-01 |
Baylor College Of Medicine |
Car t cells with one or more interleukins
|
|
EP3788369A1
(en)
|
2018-05-01 |
2021-03-10 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
CN110438082B
(zh)
*
|
2018-05-04 |
2024-03-08 |
恺兴生命科技(上海)有限公司 |
表达il-21r结合蛋白的免疫效应细胞
|
|
EP3790629A1
(en)
|
2018-05-11 |
2021-03-17 |
CRISPR Therapeutics AG |
Methods and compositions for treating cancer
|
|
GB201807870D0
(en)
|
2018-05-15 |
2018-06-27 |
Autolus Ltd |
A CD79-specific chimeric antigen receptor
|
|
AU2019269118B2
(en)
|
2018-05-15 |
2025-02-27 |
Autolus Limited |
Chimeric antigen receptor
|
|
SG11202011306TA
(en)
|
2018-05-16 |
2020-12-30 |
Janssen Biotech Inc |
Bcma/cd3 and gprdc5d/cd3 bispecific antibodies for use in cancer therapy
|
|
WO2019227003A1
(en)
|
2018-05-25 |
2019-11-28 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
CN108623683B
(zh)
*
|
2018-05-30 |
2021-06-04 |
福州迈新生物技术开发有限公司 |
抗Pax-5蛋白的单克隆抗体及其细胞株、制备方法和应用
|
|
CN108715859B
(zh)
*
|
2018-05-31 |
2021-08-03 |
中国医学科学院血液病医院(中国医学科学院血液学研究所) |
靶向cd22的嵌合抗原受体及其应用
|
|
WO2019232519A1
(en)
*
|
2018-06-01 |
2019-12-05 |
Obi Pharma, Inc. |
Combination therapy by using anti-globo h or anti-ssea-4 antibody with anti-negative immune check points antibody
|
|
US20210371932A1
(en)
|
2018-06-01 |
2021-12-02 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
|
CN110577604A
(zh)
*
|
2018-06-07 |
2019-12-17 |
亘喜生物科技(上海)有限公司 |
携带gitr共刺激信号靶向egfr的嵌合抗原受体t细胞
|
|
US20210123075A1
(en)
|
2018-06-08 |
2021-04-29 |
Novartis Ag |
Compositions and methods for immunooncology
|
|
AU2019284911B2
(en)
|
2018-06-13 |
2026-04-09 |
Novartis Ag |
BCMA chimeric antigen receptors and uses thereof
|
|
US12036240B2
(en)
|
2018-06-14 |
2024-07-16 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
TWI809130B
(zh)
|
2018-06-22 |
2023-07-21 |
美商凱特製藥公司 |
嵌合跨膜蛋白及其用途
|
|
JP7611705B2
(ja)
*
|
2018-06-22 |
2025-01-10 |
ザ ジェネラル ホスピタル コーポレイション |
Cd37及びcd19を標的とするキメラ抗原受容体
|
|
CN110623980A
(zh)
*
|
2018-06-25 |
2019-12-31 |
深圳宾德生物技术有限公司 |
靶向cd38的嵌合抗原受体t细胞在自身免疫性疾病中的应用
|
|
CN108913709A
(zh)
*
|
2018-06-26 |
2018-11-30 |
山东兴瑞生物科技有限公司 |
用于治疗hcc的核酸、其制备方法、具有该核酸的car-t细胞及细胞的制备方法
|
|
CN108866004A
(zh)
*
|
2018-06-26 |
2018-11-23 |
奥妙生物技术(广州)有限公司 |
Shp-1敲除的t细胞及其构建方法
|
|
US11203645B2
(en)
|
2018-06-27 |
2021-12-21 |
Obi Pharma, Inc. |
Glycosynthase variants for glycoprotein engineering and methods of use
|
|
WO2020006516A1
(en)
*
|
2018-06-29 |
2020-01-02 |
Gensun Biopharma, Inc. |
Antitumor immune checkpoint regulator antagonists
|
|
WO2020000465A1
(zh)
*
|
2018-06-29 |
2020-01-02 |
深圳市博奥康生物科技有限公司 |
一种制备lightr基因敲除小鼠的方法
|
|
WO2020010250A2
(en)
|
2018-07-03 |
2020-01-09 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
CN112673093A
(zh)
*
|
2018-07-04 |
2021-04-16 |
赛通免疫治疗公司 |
靶向flt3、pd-1和/或pd-l1的免疫疗法的组合物和方法
|
|
JP7623939B2
(ja)
*
|
2018-07-09 |
2025-01-29 |
マルチチュード インコーポレーテッド |
葉酸受容体アルファに特異的な抗体
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
US11952419B2
(en)
*
|
2018-07-10 |
2024-04-09 |
University Of Connecticut |
Reagents and methods for treating cancer and autoimmune disease
|
|
US10640562B2
(en)
|
2018-07-17 |
2020-05-05 |
Mcmaster University |
T cell-antigen coupler with various construct optimizations
|
|
TWI846717B
(zh)
|
2018-07-27 |
2024-07-01 |
日商第一三共股份有限公司 |
辨識抗體-藥物結合物之藥物部位的蛋白質
|
|
EP3831412A4
(en)
|
2018-07-31 |
2022-04-27 |
Daiichi Sankyo Company, Limited |
TREATMENT OF METASTATIC BRAIN TUMOR BY ADMINISTRATION OF AN ANTIBODY-DRUG CONJUGATE
|
|
SG11202100616VA
(en)
*
|
2018-08-07 |
2021-03-30 |
Purdue Research Foundation |
Rejuvenation of car t cell
|
|
SG11202101204TA
(en)
|
2018-08-09 |
2021-03-30 |
Juno Therapeutics Inc |
Processes for generating engineered cells and compositions thereof
|
|
US20210292389A1
(en)
*
|
2018-08-10 |
2021-09-23 |
Sangamo Therapeutics France |
New car constructs comprising tnfr2 domains
|
|
US20210346430A9
(en)
*
|
2018-08-26 |
2021-11-11 |
Oaiscell Biotechnologies |
Method for treating glioblastoma
|
|
US12240915B2
(en)
|
2018-08-30 |
2025-03-04 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Chimeric antigen receptor cells for treating solid tumor
|
|
PT3844267T
(pt)
|
2018-08-31 |
2025-09-30 |
Novartis Ag |
Métodos de preparação de células que expressam recetor de antigénio quimérico
|
|
WO2020047449A2
(en)
|
2018-08-31 |
2020-03-05 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
US20200080056A1
(en)
*
|
2018-09-06 |
2020-03-12 |
The Trustees Of The University Of Pennsylvania |
CRISPR-Cas9 Knock-out of SHP-1/2 to Reduce T cell Exhaustion in Adoptive Cell Therapy
|
|
EP3850088A4
(en)
|
2018-09-07 |
2023-07-19 |
Beam Therapeutics, Inc. |
Compositions and methods for improving base editing
|
|
AU2019336245B2
(en)
|
2018-09-07 |
2026-02-26 |
Beam Therapeutics Inc. |
Compositions and methods for delivering a nucleobase editing system
|
|
US12195544B2
(en)
|
2018-09-21 |
2025-01-14 |
Harpoon Therapeutics, Inc. |
EGFR binding proteins and methods of use
|
|
EP3856771A4
(en)
|
2018-09-25 |
2022-06-29 |
Harpoon Therapeutics, Inc. |
Dll3 binding proteins and methods of use
|
|
CN109265561B
(zh)
*
|
2018-09-25 |
2021-05-25 |
山东兴瑞生物科技有限公司 |
抗EGFRvⅢ安全型嵌合抗原受体、其制备方法、利用其修饰的NK细胞及应用
|
|
US20210347851A1
(en)
|
2018-09-28 |
2021-11-11 |
Novartis Ag |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
|
WO2020069405A1
(en)
|
2018-09-28 |
2020-04-02 |
Novartis Ag |
Cd22 chimeric antigen receptor (car) therapies
|
|
WO2020072700A1
(en)
|
2018-10-02 |
2020-04-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
|
CN112996809A
(zh)
*
|
2018-10-10 |
2021-06-18 |
酵活有限公司 |
结合4-1bb和肿瘤相关抗原的抗体构建体以及其用途
|
|
US12331320B2
(en)
|
2018-10-10 |
2025-06-17 |
The Research Foundation For The State University Of New York |
Genome edited cancer cell vaccines
|
|
WO2020081730A2
(en)
|
2018-10-16 |
2020-04-23 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating microenvironment
|
|
EP3640329A1
(en)
*
|
2018-10-18 |
2020-04-22 |
Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) |
Gene editing based cancer treatment
|
|
AU2019361096A1
(en)
*
|
2018-10-19 |
2021-06-03 |
Regents Of The University Of Minnesota |
NK engager molecules and methods of use thereof
|
|
WO2020081988A1
(en)
*
|
2018-10-19 |
2020-04-23 |
Memorial Sloan-Kettering Cancer Center |
Chimeric antigen receptor targeting sialyl lewis a and uses thereof
|
|
US20210379149A1
(en)
*
|
2018-10-25 |
2021-12-09 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Increasing or Maintaining T-Cell Subpopulations in Adoptive T-Cell Therapy
|
|
US12454574B2
(en)
|
2018-10-30 |
2025-10-28 |
Board Of Regents, The University Of Texas System |
Anti-CD79B antibodies and chimeric antigen receptors and methods of use thereof
|
|
SG11202104188VA
(en)
|
2018-11-01 |
2021-05-28 |
Juno Therapeutics Inc |
Methods for treatment using chimeric antigen receptors specific for b-cell maturation antigen
|
|
KR20210102231A
(ko)
*
|
2018-11-09 |
2021-08-19 |
프레드 헛친슨 켄서 리서치 센터 |
메소텔린에 특이적인 t 세포 수용체 및 면역요법에서의 그의 용도
|
|
WO2020102779A1
(en)
|
2018-11-16 |
2020-05-22 |
Albert Einstein College Of Medicine |
MONOCLONAL ANTIBODIES AGAINST IgV DOMAIN OF B7-H3 AND USES THEREOF
|
|
CN116286665A
(zh)
*
|
2018-11-16 |
2023-06-23 |
上海煦顼技术有限公司 |
嵌合抗原受体细胞分泌治疗剂
|
|
US20220033848A1
(en)
*
|
2018-11-19 |
2022-02-03 |
Board Of Regents, The University Of Texas System |
A modular, polycistronic vector for car and tcr transduction
|
|
US10918667B2
(en)
*
|
2018-11-20 |
2021-02-16 |
Innovative Cellular Therapeutics CO., LTD. |
Modified cell expressing therapeutic agent and uses thereof
|
|
JP7278379B2
(ja)
|
2018-11-29 |
2023-05-19 |
ヴィネティ インク. |
集中型及び分散型の個別化医薬プラットフォーム
|
|
US11793834B2
(en)
|
2018-12-12 |
2023-10-24 |
Kite Pharma, Inc. |
Chimeric antigen and T cell receptors and methods of use
|
|
US12600760B2
(en)
|
2018-12-13 |
2026-04-14 |
The General Hospital Corporation |
Chimeric antigen receptors targeting CD79B and CD19
|
|
US20220062394A1
(en)
|
2018-12-17 |
2022-03-03 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
|
ES2944062T3
(es)
*
|
2018-12-19 |
2023-06-19 |
Inst Nat Sante Rech Med |
Células T invariantes asociadas a la mucosa (MAIT) que expresan receptores de antígenos quiméricos
|
|
WO2020128972A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
WO2020132557A1
(en)
|
2018-12-21 |
2020-06-25 |
Compass Therapeutics Llc |
Transgenic mouse expressing common human light chain
|
|
AU2020204686A1
(en)
*
|
2019-01-04 |
2021-07-22 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
|
PH12021551676A1
(en)
*
|
2019-01-18 |
2022-03-07 |
Janssen Biotech Inc |
Gprc5d chimeric antigen receptors and cells expressing the same
|
|
CN114040977B
(zh)
|
2019-01-31 |
2024-09-03 |
比姆医疗股份有限公司 |
非靶脱氨反应减低的核碱基编辑器和用于定性核碱基编辑器的测定
|
|
AU2020223314A1
(en)
|
2019-02-13 |
2021-08-12 |
Beam Therapeutics Inc. |
Compositions and methods for treating alpha-1 antitrypsin deficiency
|
|
SG11202108346WA
(en)
|
2019-02-13 |
2021-08-30 |
Beam Therapeutics Inc |
Modified immune cells having adenosine deaminase base editors for modifying a nucleobase in a target sequence
|
|
ES3032659T3
(en)
|
2019-02-15 |
2025-07-23 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
BR112021015672A2
(pt)
|
2019-02-15 |
2021-10-05 |
Novartis Ag |
Derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona substituída e usos dos mesmos
|
|
US11321652B1
(en)
|
2019-02-20 |
2022-05-03 |
Vineti Inc. |
Smart label devices, systems, and methods
|
|
AU2020226893B2
(en)
|
2019-02-21 |
2025-02-27 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to T cell related cancer cells and uses thereof
|
|
GB2597851B
(en)
|
2019-02-21 |
2024-05-29 |
Marengo Therapeutics Inc |
Antibody molecules that bind to NKP30 and uses thereof
|
|
CA3130825A1
(en)
|
2019-02-22 |
2020-08-27 |
Garvan Institute Of Medical Research |
Methods of modulating immune response via snvs of a20 that can "tune" the immune system of a subject
|
|
US20220088075A1
(en)
|
2019-02-22 |
2022-03-24 |
The Trustees Of The University Of Pennsylvania |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
|
AU2020229806A1
(en)
|
2019-02-25 |
2021-07-29 |
Novartis Ag |
Mesoporous silica particles compositions for viral delivery
|
|
JP7810554B2
(ja)
|
2019-03-01 |
2026-02-03 |
アケロイス バイオファーマ, インコーポレイテッド |
抗原特異的免疫細胞におけるcd160機能をモジュレートする方法およびその使用
|
|
WO2020186101A1
(en)
|
2019-03-12 |
2020-09-17 |
The Broad Institute, Inc. |
Detection means, compositions and methods for modulating synovial sarcoma cells
|
|
EP3942023A1
(en)
|
2019-03-18 |
2022-01-26 |
The Broad Institute, Inc. |
Compositions and methods for modulating metabolic regulators of t cell pathogenicity
|
|
US20220168389A1
(en)
|
2019-04-12 |
2022-06-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
JP2022529280A
(ja)
*
|
2019-04-17 |
2022-06-20 |
チャ バイオテック カンパニー リミテッド |
抗癌活性が増大されたナチュラルキラー細胞、及びその免疫治療用途
|
|
EP3959320A1
(en)
|
2019-04-24 |
2022-03-02 |
Novartis AG |
Compositions and methods for selective protein degradation
|
|
US12479890B2
(en)
|
2019-04-26 |
2025-11-25 |
The University Of North Carolina At Chapel Hill |
Chimeric antigen receptor constructs and their use in CAR-T cells
|
|
AU2020267057A1
(en)
|
2019-04-30 |
2021-11-18 |
Crispr Therapeutics Ag |
Allogeneic cell therapy of B cell malignancies using genetically engineered T cells targeting CD19
|
|
EA202192964A1
(ru)
*
|
2019-04-30 |
2022-02-17 |
Мемориал Слоан-Кеттеринг Кэнсер Сентер |
Комбинированная терапия
|
|
WO2020223445A1
(en)
|
2019-04-30 |
2020-11-05 |
Senti Biosciences, Inc. |
Chimeric receptors and methods of use thereof
|
|
MX2021013223A
(es)
|
2019-05-01 |
2022-02-17 |
Juno Therapeutics Inc |
Celulas que expresan un receptor quimerico de un locus cd247 modificado, polinucleotidos relacionados y metodos.
|
|
AU2020265741A1
(en)
|
2019-05-01 |
2021-11-25 |
Editas Medicine, Inc. |
Cells expressing a recombinant receptor from a modified TGFBR2 Locus, related polynucleotides and methods
|
|
US20220235340A1
(en)
|
2019-05-20 |
2022-07-28 |
The Broad Institute, Inc. |
Novel crispr-cas systems and uses thereof
|
|
WO2020236797A1
(en)
|
2019-05-21 |
2020-11-26 |
Novartis Ag |
Variant cd58 domains and uses thereof
|
|
UY38701A
(es)
|
2019-05-21 |
2020-12-31 |
Novartis Ag |
Moléculas de unión a cd19, conjugados, composiciones que las comprenden y usos de las mismas
|
|
CN118994397A
(zh)
|
2019-05-21 |
2024-11-22 |
诺华股份有限公司 |
针对bcma的三特异性结合分子及其用途
|
|
WO2020243371A1
(en)
|
2019-05-28 |
2020-12-03 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
|
US12109235B2
(en)
|
2019-06-21 |
2024-10-08 |
Kite Pharma, Inc. |
TGF-beta receptors and methods of use
|
|
WO2021009701A1
(en)
*
|
2019-07-17 |
2021-01-21 |
Curocell Inc. |
Enhanced immune cells using dual shrna and composition including the same
|
|
AU2020319094A1
(en)
*
|
2019-07-24 |
2022-02-03 |
Eureka Therapeutics, Inc. |
Cells expressing chimeric antigen receptors and chimeric stimulating receptors and uses thereof
|
|
CA3145697A1
(en)
*
|
2019-07-30 |
2021-02-04 |
Dendrocyte Biotech Pty Ltd |
Anti-cd300f immunoconjugate
|
|
WO2021030627A1
(en)
|
2019-08-13 |
2021-02-18 |
The General Hospital Corporation |
Methods for predicting outcomes of checkpoint inhibition and treatment thereof
|
|
US12421557B2
(en)
|
2019-08-16 |
2025-09-23 |
The Broad Institute, Inc. |
Methods for predicting outcomes and treating colorectal cancer using a cell atlas
|
|
EP4013431A4
(en)
|
2019-08-18 |
2024-05-01 |
Chimera Bioengineering, Inc. |
Combination therapy with gold controlled transgenes
|
|
CN110627909B
(zh)
*
|
2019-08-28 |
2021-03-30 |
中国人民解放军第二军医大学 |
一种特异性活化nk细胞的嵌合抗原受体及其应用
|
|
WO2021041922A1
(en)
|
2019-08-30 |
2021-03-04 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
|
MX2022002747A
(es)
|
2019-09-10 |
2022-04-06 |
Obsidian Therapeutics Inc |
Proteinas de fusion de ca2-il15 para regulacion ajustable.
|
|
AU2020347171A1
(en)
|
2019-09-11 |
2022-03-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods comprising prostate stem cell antigen (PSCA) chimeric antigen receptors (CARs)
|
|
US20220333079A1
(en)
*
|
2019-09-18 |
2022-10-20 |
Slbigen Inc. |
Genetically modified nk cell line transduced with gene encoding novel chimeric antigen receptor and use thereof
|
|
WO2021057906A1
(zh)
*
|
2019-09-25 |
2021-04-01 |
科济生物医药(上海)有限公司 |
表达il-15的免疫效应细胞
|
|
CN115279398B
(zh)
|
2019-09-27 |
2025-07-04 |
比姆医疗股份有限公司 |
治疗液态癌症的组合物和方法
|
|
US12297426B2
(en)
|
2019-10-01 |
2025-05-13 |
The Broad Institute, Inc. |
DNA damage response signature guided rational design of CRISPR-based systems and therapies
|
|
US12394502B2
(en)
|
2019-10-02 |
2025-08-19 |
The General Hospital Corporation |
Method for predicting HLA-binding peptides using protein structural features
|
|
US11981922B2
(en)
|
2019-10-03 |
2024-05-14 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
|
|
US12195725B2
(en)
|
2019-10-03 |
2025-01-14 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for modulating and detecting tissue specific TH17 cell pathogenicity
|
|
US11793787B2
(en)
|
2019-10-07 |
2023-10-24 |
The Broad Institute, Inc. |
Methods and compositions for enhancing anti-tumor immunity by targeting steroidogenesis
|
|
US12552865B2
(en)
|
2019-10-22 |
2026-02-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
High affinity nanobodies targeting B7-H3 (CD276) for treating multiple solid tumors
|
|
EP4048402A4
(en)
*
|
2019-10-23 |
2023-11-22 |
Cue Biopharma, Inc. |
MODIFIED CYTOTOXIC T CELLS AND METHOD OF USE THEREOF
|
|
AU2020370292A1
(en)
*
|
2019-10-23 |
2022-03-03 |
Cue Biopharma, Inc. |
T-cell modulatory chimeric molecules and methods of use thereof
|
|
US20210130438A1
(en)
*
|
2019-10-28 |
2021-05-06 |
The Broad Institute, Inc. |
Pan-cancer t cell exhaustion genes
|
|
CN110627903B
(zh)
*
|
2019-10-29 |
2021-09-21 |
河南大学 |
抗cd97单克隆抗体、其可变区与恒定区序列及应用
|
|
EP4054601A4
(en)
*
|
2019-11-04 |
2024-08-21 |
Secura Bio, Inc. |
MANUFACTURING PROCESSES FOR CELLULAR THERAPIES
|
|
US20230016709A1
(en)
*
|
2019-11-25 |
2023-01-19 |
St. Jude Children's Research Hospital |
Use of protease serine 21 (prss21) antigen testing in the diagnosis and treatment of acute myeloid leukemia
|
|
EP4065158A2
(en)
|
2019-11-26 |
2022-10-05 |
Novartis AG |
Chimeric antigen receptors binding bcma and cd19 and uses thereof
|
|
KR20220104217A
(ko)
|
2019-11-26 |
2022-07-26 |
노파르티스 아게 |
Cd19 및 cd22 키메라 항원 수용체 및 이의 용도
|
|
US12616734B2
(en)
|
2019-11-28 |
2026-05-05 |
CentricsBio, Inc. |
Chimeric antigen receptor specifically binding to cd 300C antigen or receptor thereof
|
|
CN115038719B
(zh)
*
|
2019-11-28 |
2025-05-20 |
善萃科思生物科技公司 |
与cd300c抗原或其受体特异性结合的嵌合抗原受体
|
|
AU2020401755A1
(en)
*
|
2019-12-11 |
2022-08-04 |
Cilag Gmbh International |
Multispecific binding molecules comprising LTBR and EDB binding domains and uses thereof
|
|
US20250320269A1
(en)
*
|
2019-12-18 |
2025-10-16 |
Albert Einstein College Of Medicine |
Chimeric antigen receptors targeting b7-h3 (cd276) and associated methods
|
|
KR20220116257A
(ko)
|
2019-12-20 |
2022-08-22 |
노파르티스 아게 |
골수섬유증 및 골수이형성 증후군을 치료하기 위한, 데시타빈 또는 항 pd-1 항체 스파르탈리주맙을 포함하거나 또는 포함하지 않는, 항 tim-3 항체 mbg453 및 항 tgf-베타 항체 nis793의 조합물
|
|
AU2020416273A1
(en)
|
2020-01-03 |
2022-07-28 |
Marengo Therapeutics, Inc. |
Anti-TCR antibody molecules and uses thereof
|
|
MX2022008415A
(es)
*
|
2020-01-08 |
2022-08-08 |
Obsidian Therapeutics Inc |
Composiciones y metodos para la regulacion ajustable de la transcripcion.
|
|
CN115427084A
(zh)
*
|
2020-01-10 |
2022-12-02 |
T细胞受体治疗公司 |
用于自身免疫调节的组合物和方法
|
|
US12165747B2
(en)
|
2020-01-23 |
2024-12-10 |
The Broad Institute, Inc. |
Molecular spatial mapping of metastatic tumor microenvironment
|
|
WO2021163618A1
(en)
|
2020-02-14 |
2021-08-19 |
Novartis Ag |
Method of predicting response to chimeric antigen receptor therapy
|
|
US12076343B2
(en)
|
2020-02-19 |
2024-09-03 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Engineered safety in cell therapy
|
|
MX2022010685A
(es)
|
2020-02-27 |
2022-09-23 |
Novartis Ag |
Metodos de produccion de celulas que expresan receptores de antigeno quimericos.
|
|
CN115175695A
(zh)
|
2020-02-27 |
2022-10-11 |
诺华股份有限公司 |
制备表达嵌合抗原受体的细胞的方法
|
|
WO2021222944A1
(en)
*
|
2020-04-30 |
2021-11-04 |
Board Of Regents, The University Of Texas System |
Anti-cd79b antibodies and chimeric antigen receptors and methods of use thereof
|
|
CA3177488A1
(en)
*
|
2020-05-05 |
2021-11-11 |
Robert Hofmeister |
Compositions and methods for tcr reprogramming using cd70 specific fusion proteins
|
|
WO2021231376A2
(en)
|
2020-05-12 |
2021-11-18 |
Cue Biopharma, Inc. |
Multimeric t-cell modulatory polypeptides and methods of use thereof
|
|
US12043654B2
(en)
|
2020-06-02 |
2024-07-23 |
Innovative Cellular Therapeutics Holdings, Ltd. |
Anti-GCC antibody and CAR thereof for treating digestive system cancer
|
|
KR20220166837A
(ko)
*
|
2020-06-11 |
2022-12-19 |
난징 바이오흐엥 바이오테크 씨오., 엘티디 |
Nk억제 분자를 발현하는 조작된 면역 세포 및 그 용도
|
|
US20230416359A1
(en)
*
|
2020-06-17 |
2023-12-28 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Olfactory receptors for use as targets for antigen binding molecules to detect and treat cancer
|
|
EP4170020A4
(en)
*
|
2020-06-17 |
2025-01-22 |
Kyoto University |
IMMUNOCOMPETENT CELLS WITH CHIMERIC ANTIGEN RECEPTOR EXPRESSION
|
|
JP2023530997A
(ja)
*
|
2020-06-19 |
2023-07-20 |
ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム |
Bst2ロングアイソフォームを標的化する抗bst2抗体
|
|
US12240899B2
(en)
|
2020-06-22 |
2025-03-04 |
Ngm Biopharmaceuticals, Inc. |
LAIR-1-binding agents and methods of use thereof
|
|
CN115916199A
(zh)
|
2020-06-23 |
2023-04-04 |
诺华股份有限公司 |
包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案
|
|
WO2021260186A1
(en)
|
2020-06-26 |
2021-12-30 |
Juno Therapeutics Gmbh |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
|
CN116490518A
(zh)
|
2020-07-17 |
2023-07-25 |
西穆尔克斯股份有限公司 |
用于重定向免疫抑制信号传导的嵌合MyD88受体及相关组合物和方法
|
|
US20230271940A1
(en)
|
2020-08-03 |
2023-08-31 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US12122839B2
(en)
|
2020-08-05 |
2024-10-22 |
Synthekine, Inc. |
IFNGR binding synthetic cytokines and methods of use
|
|
US12234291B2
(en)
|
2020-08-05 |
2025-02-25 |
Synthekine, Inc. |
IL2RB binding molecules and methods of use
|
|
BR112023001723A2
(pt)
|
2020-08-05 |
2023-05-02 |
Synthekine Inc |
Moléculas de ligação à gp130 e métodos de uso
|
|
WO2022031870A1
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
IL27Rα BINDING MOLECULES AND METHODS OF USE
|
|
US12540188B2
(en)
|
2020-08-05 |
2026-02-03 |
Synthekine, Inc. |
IL10Rα/IL2Rγ synthetic cytokines
|
|
CN116829585A
(zh)
|
2020-08-05 |
2023-09-29 |
辛德凯因股份有限公司 |
Il27受体结合相关的组合物和方法
|
|
WO2022031890A1
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Ifngr2 binding molecules and methods of use
|
|
US12077594B2
(en)
*
|
2020-08-05 |
2024-09-03 |
Synthekine, Inc. |
IL2RG binding molecules and methods of use
|
|
EP4192880A4
(en)
|
2020-08-05 |
2025-04-30 |
Synthekine, Inc. |
IL10 receptor-binding molecules and methods of use
|
|
WO2022031885A2
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il10ra binding molecules and methods of use
|
|
KR20230084470A
(ko)
|
2020-08-14 |
2023-06-13 |
카이트 파마 인코포레이티드 |
면역 세포 기능의 향상
|
|
WO2022036495A1
(en)
|
2020-08-17 |
2022-02-24 |
Utc Therapeutics Inc. |
Lymphocytes-antigen presenting cells co-stimulators and uses thereof
|
|
TW202227124A
(zh)
|
2020-08-21 |
2022-07-16 |
瑞士商諾華公司 |
用於體內產生car表現細胞的組成物和方法
|
|
US12576151B2
(en)
|
2020-09-25 |
2026-03-17 |
Beam Therapeutics Inc. |
Fratricide resistant modified immune cells and methods of using the same
|
|
CN116601176A
(zh)
*
|
2020-09-30 |
2023-08-15 |
中国科学院动物研究所 |
靶向egfr的嵌合抗原受体
|
|
CN114369168B
(zh)
*
|
2020-10-19 |
2024-08-30 |
南京卡提医学科技有限公司 |
包含dap12和共刺激信号分子信号域的嵌合受体及其使用方法
|
|
CN114426583B
(zh)
*
|
2020-10-29 |
2023-10-10 |
中国科学技术大学 |
用于急性髓系白血病的细胞疗法的嵌合抗原受体
|
|
MX2023005609A
(es)
|
2020-11-13 |
2023-05-29 |
Novartis Ag |
Terapias de combinacion con celulas que expresan receptores quimericos para el antigeno (car).
|
|
WO2022109023A1
(en)
*
|
2020-11-17 |
2022-05-27 |
Igm Biosciences, Inc. |
Uses of effector cell engaging molecules with moieties of differing potencies
|
|
EP4247853A4
(en)
*
|
2020-11-20 |
2025-02-12 |
Bliss Biopharmaceutical (Hangzhou) Co., Ltd. |
MODIFIED EGFR ANTIBODY WITH REDUCED AFFINITY, DRUG CONJUGATE AND USE THEREOF
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
TW202237827A
(zh)
|
2020-12-03 |
2022-10-01 |
美商世紀治療股份有限公司 |
經基因工程改造之細胞及其用途
|
|
TW202237638A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
烏苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
|
CN113896795B
(zh)
|
2020-12-11 |
2022-07-15 |
广州百暨基因科技有限公司 |
抗cll1抗体及其应用
|
|
CN113234169B
(zh)
|
2020-12-11 |
2022-11-01 |
广州百暨基因科技有限公司 |
靶向cll1嵌合抗原受体及其应用
|
|
JP2024500847A
(ja)
|
2020-12-18 |
2024-01-10 |
センチュリー セラピューティクス,インコーポレイテッド |
適合可能な受容体特異性を有するキメラ抗原受容体システム
|
|
US20240216427A1
(en)
*
|
2020-12-30 |
2024-07-04 |
St. Jude Children's Research Hospital, Inc. |
Chimeric antigen receptors targeting splice variants of the extracellular matrix proteins tenascin c (tnc) and procollagen 11a1 (col11a1)
|
|
WO2022147481A1
(en)
|
2020-12-30 |
2022-07-07 |
Ansun Biopharma Inc. |
Combination therapy of an oncolytic virus delivering a foreign antigen and an engineered immune cell expressing a chimeric receptor targeting the foreign antigen
|
|
CN117062611A
(zh)
|
2021-01-26 |
2023-11-14 |
惠和生物技术(上海)有限公司 |
嵌合抗原受体(car)构建体和表达car构建体的nk细胞
|
|
CA3206241A1
(en)
*
|
2021-01-29 |
2022-01-28 |
Guoqing Cao |
Antigen binding protein and use thereof
|
|
US20240082306A1
(en)
*
|
2021-02-03 |
2024-03-14 |
Bioheng Therapeutics Limited |
Novel chimeric antigen receptor and use thereof
|
|
CN112851826B
(zh)
*
|
2021-02-10 |
2023-08-11 |
上海煦顼技术有限公司 |
Upk2嵌合抗原受体及其尿道癌的治疗
|
|
KR102671410B1
(ko)
*
|
2021-03-03 |
2024-06-04 |
진화섭 |
RANK 리간드(RANK ligand)에 특이적으로 결합하는 키메릭 항원 수용체 및 이의 용도
|
|
WO2022192439A1
(en)
|
2021-03-11 |
2022-09-15 |
Kite Pharma, Inc. |
Improving immune cell function
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
JP2024515662A
(ja)
*
|
2021-04-23 |
2024-04-10 |
ソレント・セラピューティクス・インコーポレイテッド |
Gd2に結合する二量体抗原受容体(dar)
|
|
TW202309294A
(zh)
|
2021-04-27 |
2023-03-01 |
瑞士商諾華公司 |
病毒載體生產系統
|
|
JP2024518421A
(ja)
*
|
2021-05-07 |
2024-05-01 |
ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム |
キメラ抗原受容体(car)t細胞治療に関連する血清メタボロミクス
|
|
WO2022247756A1
(zh)
*
|
2021-05-23 |
2022-12-01 |
上海邦耀生物科技有限公司 |
靶向gprc5d的嵌合抗原受体及其用途
|
|
EP4347660A4
(en)
|
2021-06-01 |
2025-06-04 |
Triumvira Immunologics USA, Inc. |
CLAUDIN-18.2 T-CELL ANTIGEN COUPLER AND USES THEREOF
|
|
CN117730100A
(zh)
|
2021-06-08 |
2024-03-19 |
凯德药业股份有限公司 |
Gpc3结合分子
|
|
JP2024523316A
(ja)
*
|
2021-06-18 |
2024-06-28 |
オートラス リミテッド |
Car t細胞における、および疾患の処置のための抗cd307e単一ドメイン抗体、その使用
|
|
JP2024531364A
(ja)
|
2021-08-20 |
2024-08-29 |
ノバルティス アーゲー |
キメラ抗原受容体発現細胞を作製する方法
|
|
EP4141028A1
(en)
|
2021-08-31 |
2023-03-01 |
Johann-Wolfgang-Goethe-Universität Frankfurt am Main |
Personalized vnar-based chimeric antigen receptors (vnar-car) for the treatment of clonal b-and t cell malignancies, and methods for producing vnar-cars
|
|
WO2023056194A2
(en)
|
2021-09-29 |
2023-04-06 |
Chimera Bioengineering, Inc. |
Compositions and methods for anti-tnmuc1 gold car t-cells
|
|
US11615874B1
(en)
|
2021-09-30 |
2023-03-28 |
Vineti Inc. |
Personalized medicine and therapies platform
|
|
IL311570A
(en)
|
2021-10-14 |
2024-05-01 |
Arsenal Biosciences Inc |
Immune cells with common expression chain and logic gate systems
|
|
CN119120424A
(zh)
|
2021-11-02 |
2024-12-13 |
辉大(上海)生物科技有限公司 |
一种CRISPR-Cas12i系统
|
|
EP4493581A1
(en)
*
|
2022-03-18 |
2025-01-22 |
University of Rochester |
Combination therapy for treatment of cancer, methods and systems of delivery thereof
|
|
CN114805584B
(zh)
*
|
2022-06-30 |
2022-09-09 |
上海优替济生生物医药有限公司 |
抗原结合蛋白及其用途
|
|
EP4556018A1
(en)
*
|
2022-07-13 |
2025-05-21 |
Osaka University |
Agent for preventing and/or treating tumor
|
|
WO2024044670A1
(en)
|
2022-08-26 |
2024-02-29 |
Kite Pharma, Inc. |
Improving immune cell function
|
|
IL319225A
(en)
|
2022-09-15 |
2025-04-01 |
Novartis Ag |
Treatment of autoimmune disorders using antigen receptor chemotherapeutics
|
|
WO2024077256A1
(en)
|
2022-10-07 |
2024-04-11 |
The General Hospital Corporation |
Methods and compositions for high-throughput discovery ofpeptide-mhc targeting binding proteins
|
|
AU2023369684A1
(en)
|
2022-10-26 |
2025-04-17 |
Novartis Ag |
Lentiviral formulations
|
|
WO2024112711A2
(en)
|
2022-11-21 |
2024-05-30 |
Iovance Biotherapeutics, Inc. |
Methods for assessing proliferation potency of gene-edited t cells
|
|
WO2024124044A1
(en)
|
2022-12-07 |
2024-06-13 |
The Brigham And Women’S Hospital, Inc. |
Compositions and methods targeting sat1 for enhancing anti¬ tumor immunity during tumor progression
|
|
WO2024178397A2
(en)
|
2023-02-24 |
2024-08-29 |
Elevatebio Technologies, Inc. |
Modified immune effector cells and methods of use
|
|
JP2026507228A
(ja)
|
2023-03-03 |
2026-02-27 |
アーセナル バイオサイエンシズ インコーポレイテッド |
Psma及びca9を標的とするシステム
|
|
EP4694916A1
(en)
*
|
2023-04-14 |
2026-02-18 |
SOTIO Biotech Inc. |
Engineered immune cells for treating cancer in combination with il-2/il-15 receptor ?? agonists
|
|
WO2024215987A1
(en)
*
|
2023-04-14 |
2024-10-17 |
Sotio Biotech Inc. |
IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES
|
|
WO2025007073A2
(en)
|
2023-06-29 |
2025-01-02 |
Dispatch Biotherapeutics, Inc. |
Synthetic cytokine receptors
|
|
TW202521564A
(zh)
|
2023-08-14 |
2025-06-01 |
美商英特利亞醫療公司 |
用於基於細胞之療法的cd70 car-t組合物及方法
|
|
EP4520346A1
(en)
|
2023-09-06 |
2025-03-12 |
Gyncentrum Sp. z o.o. |
Cells, methods and systems for use in the treatment of a cancer with dual-car-t
|
|
WO2025059162A1
(en)
|
2023-09-11 |
2025-03-20 |
Dana-Farber Cancer Institute, Inc. |
Car-engager containing il-2 variants to enhance the functionality of car t cells
|
|
WO2025059533A1
(en)
|
2023-09-13 |
2025-03-20 |
The Broad Institute, Inc. |
Crispr enzymes and systems
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
WO2025117544A1
(en)
|
2023-11-29 |
2025-06-05 |
The Broad Institute, Inc. |
Engineered omega guide molecule and iscb compositions, systems, and methods of use thereof
|
|
WO2025249478A1
(ja)
*
|
2024-05-29 |
2025-12-04 |
第一三共株式会社 |
抗gpr20 carおよびそれを含む細胞
|
|
WO2026006767A1
(en)
|
2024-06-28 |
2026-01-02 |
Dispatch Biotherapeutics, Inc. |
Tethered il-9/il-9r and related engineered cells and methods
|
|
WO2026008700A1
(en)
|
2024-07-03 |
2026-01-08 |
Immunofusion Bv |
Il7r alpha signalling domain, chimeric antigen receptor and uses thereof
|