PL3737765T5 - Komórki układu odpornościowego wzmocnione z użyciem podwójnego shrna i kompozycja zawierająca te komórki - Google Patents
Komórki układu odpornościowego wzmocnione z użyciem podwójnego shrna i kompozycja zawierająca te komórkiInfo
- Publication number
- PL3737765T5 PL3737765T5 PL19738866.3T PL19738866T PL3737765T5 PL 3737765 T5 PL3737765 T5 PL 3737765T5 PL 19738866 T PL19738866 T PL 19738866T PL 3737765 T5 PL3737765 T5 PL 3737765T5
- Authority
- PL
- Poland
- Prior art keywords
- same
- immune cells
- composition including
- enhanced immune
- shrna
- Prior art date
Links
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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| PCT/IB2019/050194 WO2019138354A1 (en) | 2018-01-12 | 2019-01-10 | Enhanced immune cells using dual shrna and composition including the same |
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| PL3737765T3 PL3737765T3 (pl) | 2022-04-11 |
| PL3737765T5 true PL3737765T5 (pl) | 2025-05-05 |
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| US (4) | US11679129B2 (pl) |
| EP (2) | EP3737765B2 (pl) |
| JP (3) | JP7068498B2 (pl) |
| KR (2) | KR102805915B1 (pl) |
| CN (1) | CN111801421B (pl) |
| AU (2) | AU2019206425B2 (pl) |
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| PT (1) | PT3737765T (pl) |
| SG (1) | SG11202006606YA (pl) |
| WO (1) | WO2019138354A1 (pl) |
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| JP7068498B2 (ja) | 2018-01-12 | 2022-05-16 | クロセル インク. | 二重shRNAを用いて強化された免疫細胞及びそれを含む組成物 |
| CN109485732B (zh) * | 2018-12-20 | 2021-09-24 | 四川大学华西医院 | 基因工程修饰的双靶点嵌合抗原受体及其用途 |
| CN118546959A (zh) | 2019-03-05 | 2024-08-27 | 恩卡尔塔公司 | Cd19定向性嵌合抗原受体及其在免疫疗法中的用途 |
| JP7633180B2 (ja) * | 2019-05-02 | 2025-02-19 | セリアド オンコロジー エス.アー. | マルチプレックス化干渉rnaを有する細胞 |
| KR20220081972A (ko) * | 2019-07-17 | 2022-06-16 | 주식회사 큐로셀 | 이중 shrna를 이용하는 향상된 면역 세포 및 이를 포함하는 조성물 |
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| EP4282963A1 (en) | 2022-05-23 | 2023-11-29 | Eberhard Karls Universität Tübingen, Medizinische Fakultät | Nucleic acid modified biological cell with expansion-dependent gene expression |
| CN114836428B (zh) * | 2022-06-08 | 2024-03-26 | 华东师范大学 | 一种tigit基因干扰的嵌合抗原受体nk细胞及其应用 |
| WO2023238103A1 (en) * | 2022-06-10 | 2023-12-14 | Curocell Inc. | Car-t therapy for treating cancer |
| CN116983322A (zh) * | 2022-09-15 | 2023-11-03 | 圣诺生物医药技术(苏州)有限公司 | 用于治疗肺癌、胰腺癌、肝癌和结直肠癌的小核酸干扰药物 |
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| CN116515836B (zh) * | 2023-05-09 | 2023-12-01 | 中国人民解放军军事科学院军事医学研究院 | 抑制MerTK表达的shRNA、腺相关病毒及其应用 |
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2019
- 2019-01-10 JP JP2020559043A patent/JP7068498B2/ja active Active
- 2019-01-10 CN CN201980016378.1A patent/CN111801421B/zh active Active
- 2019-01-10 WO PCT/IB2019/050194 patent/WO2019138354A1/en not_active Ceased
- 2019-01-10 PL PL19738866.3T patent/PL3737765T5/pl unknown
- 2019-01-10 SG SG11202006606YA patent/SG11202006606YA/en unknown
- 2019-01-10 EP EP19738866.3A patent/EP3737765B2/en active Active
- 2019-01-10 PT PT197388663T patent/PT3737765T/pt unknown
- 2019-01-10 EP EP21207719.2A patent/EP4006153B1/en active Active
- 2019-01-10 AU AU2019206425A patent/AU2019206425B2/en active Active
- 2019-01-10 US US16/958,649 patent/US11679129B2/en active Active
- 2019-01-10 ES ES21207719T patent/ES2990966T3/es active Active
- 2019-01-10 CA CA3088234A patent/CA3088234A1/en active Pending
- 2019-01-10 KR KR1020217036928A patent/KR102805915B1/ko active Active
- 2019-01-10 ES ES19738866T patent/ES2908324T5/es active Active
- 2019-01-10 KR KR1020207023221A patent/KR102327512B1/ko active Active
- 2019-01-10 FI FIEP19738866.3T patent/FI3737765T4/fi active
- 2019-01-10 DK DK19738866.3T patent/DK3737765T4/da active
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2021
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2022
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- 2022-04-28 JP JP2022074779A patent/JP7394914B2/ja active Active
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2023
- 2023-05-15 US US18/317,797 patent/US20230381236A1/en active Pending
- 2023-11-28 JP JP2023200890A patent/JP7763824B2/ja active Active
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2025
- 2025-04-22 AU AU2025202789A patent/AU2025202789A1/en not_active Abandoned
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