DK0666868T3 - Anvendelse af anti-VEGF-antistoffer til behandling af cancer - Google Patents

Anvendelse af anti-VEGF-antistoffer til behandling af cancer

Info

Publication number
DK0666868T3
DK0666868T3 DK92923512T DK92923512T DK0666868T3 DK 0666868 T3 DK0666868 T3 DK 0666868T3 DK 92923512 T DK92923512 T DK 92923512T DK 92923512 T DK92923512 T DK 92923512T DK 0666868 T3 DK0666868 T3 DK 0666868T3
Authority
DK
Denmark
Prior art keywords
hvegf
antagonist
treat cancer
hvegfr
tumour
Prior art date
Application number
DK92923512T
Other languages
English (en)
Other versions
DK0666868T4 (da
Inventor
Kyung Jin Kim
Napoleone Ferrara
Original Assignee
Genentech Inc
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Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44652081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0666868(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK0666868T3 publication Critical patent/DK0666868T3/da
Publication of DK0666868T4 publication Critical patent/DK0666868T4/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK92923512T 1992-10-28 1992-10-28 Anvendelse af anti-VEGF-antistoffer til behandling af cancer DK0666868T4 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1992/009218 WO1994010202A1 (en) 1992-10-28 1992-10-28 Vascular endothelial cell growth factor antagonists

Publications (2)

Publication Number Publication Date
DK0666868T3 true DK0666868T3 (da) 2002-07-29
DK0666868T4 DK0666868T4 (da) 2006-09-18

Family

ID=44652081

Family Applications (4)

Application Number Title Priority Date Filing Date
DK08010320.3T DK1975181T3 (da) 1992-10-28 1992-10-28 Anvendelse af vaskulære endothelcelle-vækstfaktor-antagonister
DK92923512T DK0666868T4 (da) 1992-10-28 1992-10-28 Anvendelse af anti-VEGF-antistoffer til behandling af cancer
DK01119430T DK1167384T3 (da) 1992-10-28 1992-10-28 Vaskular endotheliel cellevækstfaktor antagonister
DK02006351T DK1238986T3 (da) 1992-10-28 1992-10-28 Anvendelse af antagonister mod vaskulær endotelcellevækstfaktor

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK08010320.3T DK1975181T3 (da) 1992-10-28 1992-10-28 Anvendelse af vaskulære endothelcelle-vækstfaktor-antagonister

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK01119430T DK1167384T3 (da) 1992-10-28 1992-10-28 Vaskular endotheliel cellevækstfaktor antagonister
DK02006351T DK1238986T3 (da) 1992-10-28 1992-10-28 Anvendelse af antagonister mod vaskulær endotelcellevækstfaktor

Country Status (18)

Country Link
EP (4) EP0666868B2 (da)
JP (1) JP3398382B2 (da)
KR (1) KR100335584B1 (da)
AT (4) ATE348110T1 (da)
AU (1) AU687727B2 (da)
BG (1) BG99605A (da)
BR (1) BR9207175A (da)
CA (1) CA2145985C (da)
CZ (1) CZ291047B6 (da)
DE (3) DE69233739D1 (da)
DK (4) DK1975181T3 (da)
ES (4) ES2309119T3 (da)
FI (1) FI951987A (da)
HU (2) HU221343B1 (da)
NO (1) NO321825B1 (da)
RO (1) RO119721B1 (da)
SK (1) SK285035B6 (da)
WO (1) WO1994010202A1 (da)

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