DK2056874T3 - Tumorterapi med et anti-vegf-antistof - Google Patents
Tumorterapi med et anti-vegf-antistofInfo
- Publication number
- DK2056874T3 DK2056874T3 DK07786693.7T DK07786693T DK2056874T3 DK 2056874 T3 DK2056874 T3 DK 2056874T3 DK 07786693 T DK07786693 T DK 07786693T DK 2056874 T3 DK2056874 T3 DK 2056874T3
- Authority
- DK
- Denmark
- Prior art keywords
- vegf antibody
- tumor therapy
- tumor
- therapy
- vegf
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06017330 | 2006-08-21 | ||
PCT/EP2007/007276 WO2008022746A1 (en) | 2006-08-21 | 2007-08-17 | Tumor therapy with an anti-vegf antibody |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2056874T3 true DK2056874T3 (da) | 2012-10-15 |
Family
ID=37607207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07786693.7T DK2056874T3 (da) | 2006-08-21 | 2007-08-17 | Tumorterapi med et anti-vegf-antistof |
Country Status (29)
Country | Link |
---|---|
US (6) | US20080050385A1 (da) |
EP (2) | EP2441472B1 (da) |
JP (3) | JP2010501498A (da) |
KR (1) | KR101136763B1 (da) |
CN (1) | CN101505792B (da) |
AR (1) | AR062419A1 (da) |
AU (1) | AU2007287794B2 (da) |
BR (1) | BRPI0715829A2 (da) |
CA (1) | CA2660681A1 (da) |
CL (1) | CL2007002404A1 (da) |
CO (1) | CO6150193A2 (da) |
CR (1) | CR10590A (da) |
DK (1) | DK2056874T3 (da) |
ES (2) | ES2392630T3 (da) |
HK (1) | HK1134441A1 (da) |
IL (2) | IL196810A0 (da) |
MA (1) | MA30654B1 (da) |
MX (1) | MX2009001715A (da) |
MY (1) | MY150756A (da) |
NO (1) | NO20090450L (da) |
NZ (1) | NZ574580A (da) |
PE (1) | PE20080911A1 (da) |
PL (1) | PL2056874T3 (da) |
RU (1) | RU2528884C2 (da) |
SG (1) | SG174090A1 (da) |
SI (1) | SI2056874T1 (da) |
TW (2) | TW201107346A (da) |
WO (1) | WO2008022746A1 (da) |
ZA (1) | ZA200901200B (da) |
Families Citing this family (31)
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SI1282443T1 (sl) * | 2000-05-19 | 2010-01-29 | Genentech Inc | Metoda detekcije gena za izboljšanje verjetnosti učinkovitega odziva na terapijo raka z antagonistom ErbB |
ZA200701234B (en) * | 2004-07-22 | 2008-12-31 | Genentech Inc | HER2 antibody composition |
JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
KR20070085855A (ko) * | 2004-12-07 | 2007-08-27 | 제넨테크, 인크. | Her 억제제를 이용한 치료를 위한 환자 선택 방법 |
CA2592177A1 (en) * | 2005-01-21 | 2006-07-27 | Genentech, Inc. | Fixed dosing of her antibodies |
BRPI0606542A8 (pt) | 2005-02-23 | 2018-03-20 | Genentech Inc | métodos para aumentar o tempo de progressão de uma doença (ttp) |
PE20070207A1 (es) * | 2005-07-22 | 2007-03-09 | Genentech Inc | Tratamiento combinado de los tumores que expresan el her |
PL2056874T3 (pl) * | 2006-08-21 | 2013-02-28 | Hoffmann La Roche | Leczenie nowotworu przeciwciałem przeciw VEGF |
CA2677108A1 (en) | 2007-03-02 | 2008-09-12 | Genentech, Inc. | Predicting response to a her inhibitor |
TWI472339B (zh) | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至her2結構域ii之抗體及其酸性變異體的組合物 |
BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
NZ604007A (en) | 2010-05-27 | 2015-03-27 | Genmab As | Monoclonal antibodies against her2 epitope |
IL299365A (en) | 2010-05-27 | 2023-02-01 | Genmab As | Monoclonal antibodies against 2HER |
CA2804348A1 (en) * | 2010-07-19 | 2012-01-26 | F. Hoffmann-La Roche Ag | Blood plasma biomarkers for bevacizumab combination therapies for treatment of pancreatic cancer |
DK2606070T3 (da) * | 2010-08-20 | 2017-03-27 | Novartis Ag | Antistoffer for den epidermiske vækstfaktorreceptor 3 (HER3) |
US20140170149A1 (en) | 2011-04-20 | 2014-06-19 | Genmab A/S | Bispecific antibodies against her2 and cd3 |
KR102099991B1 (ko) | 2011-10-14 | 2020-04-14 | 제넨테크, 인크. | Her2 이량체화 억제제인 페르투주맙의 용도 및 이를 포함하는 제조품 |
RU2014125520A (ru) * | 2011-12-05 | 2016-02-10 | Ф. Хоффманн-Ля Рош Аг | Биомаркеры плазмы крови в случае комбинированной терапии бевацизумабом для лечения рака груди |
WO2013148159A1 (en) * | 2012-03-30 | 2013-10-03 | Fibrogen Inc | Therapeutic methods for peritoneal carcinomatosis |
MY173295A (en) | 2013-04-16 | 2020-01-14 | Genentech Inc | Pertuzumab variants and evaluation thereof |
WO2015164665A1 (en) | 2014-04-25 | 2015-10-29 | Genentech, Inc. | Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab |
TW201619200A (zh) * | 2014-10-10 | 2016-06-01 | 麥迪紐有限責任公司 | 人類化抗-ox40抗體及其用途 |
WO2016196373A2 (en) | 2015-05-30 | 2016-12-08 | Genentech, Inc. | Methods of treating her2-positive metastatic breast cancer |
WO2017087280A1 (en) | 2015-11-16 | 2017-05-26 | Genentech, Inc. | Methods of treating her2-positive cancer |
CN106729743B (zh) * | 2015-11-23 | 2021-09-21 | 四川科伦博泰生物医药股份有限公司 | 抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用 |
TW202140776A (zh) * | 2016-04-26 | 2021-11-01 | 美商美國泰福生技股份有限公司 | 細胞培養基 |
US20180221481A1 (en) | 2016-12-28 | 2018-08-09 | Genentech, Inc. | Treatment of advanced her2 expressing cancer |
TW202138007A (zh) | 2017-01-17 | 2021-10-16 | 美商建南德克公司 | 皮下her2抗體調配物 |
EP3589661B1 (en) | 2017-03-02 | 2023-11-01 | Genentech, Inc. | Adjuvant treatment of her2-positive breast cancer |
CN110536969A (zh) | 2017-04-24 | 2019-12-03 | 豪夫迈·罗氏有限公司 | 跨膜或近膜域中的erbb2/her2突变 |
JP2023541141A (ja) * | 2020-09-04 | 2023-09-28 | ザ ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ | がんを治療するための組み合わせ組成物及び方法 |
Family Cites Families (41)
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WO1989006692A1 (en) | 1988-01-12 | 1989-07-27 | Genentech, Inc. | Method of treating tumor cells by inhibiting growth factor receptor function |
WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
LU91067I2 (fr) | 1991-06-14 | 2004-04-02 | Genentech Inc | Trastuzumab et ses variantes et dérivés immuno chimiques y compris les immotoxines |
RO119721B1 (ro) | 1992-10-28 | 2005-02-28 | Genentech Inc. | Antagonişti ai factorului de creştere al celulelor vasculare endoteliale |
EP0907649A1 (en) | 1996-06-27 | 1999-04-14 | Pfizer Inc. | Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use as farnesyl protein transferase inhibitors |
WO1998017797A1 (en) | 1996-10-18 | 1998-04-30 | Genentech, Inc. | ANTI-ErbB2 ANTIBODIES |
US6884879B1 (en) * | 1997-04-07 | 2005-04-26 | Genentech, Inc. | Anti-VEGF antibodies |
ES2256935T3 (es) | 1997-04-07 | 2006-07-16 | Genentech, Inc. | Anticuerpos humanizadores y procedimiento para producirlos. |
AU743758B2 (en) | 1997-04-07 | 2002-02-07 | Genentech Inc. | Anti-VEGF antibodies |
US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
ZA9811162B (en) | 1997-12-12 | 2000-06-07 | Genentech Inc | Treatment with anti-ERBB2 antibodies. |
JPH11236333A (ja) | 1997-12-30 | 1999-08-31 | Pfizer Prod Inc | 抗ガン剤として有用なイミダゾリン−4−オン誘導体 |
SK17282000A3 (sk) | 1998-05-15 | 2002-04-04 | Imclone Systems Incorporated | Nerádioaktívne označený inhibítor proteínového tyrozínkynázového receptora |
CA2341690C (en) | 1998-08-27 | 2007-04-17 | Pfizer Products Inc. | Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents |
ATE289602T1 (de) | 1998-08-27 | 2005-03-15 | Pfizer Prod Inc | Quinolin-2-on-derivate verwendbar als antikrebsmittel |
PT1135498E (pt) | 1998-11-18 | 2008-04-30 | Genentech Inc | Variantes de anticorpos com maior afinidade de ligação em comparação com os anticorpos parentais |
EP1006113A1 (en) | 1998-12-02 | 2000-06-07 | Pfizer Products Inc. | Derivatives of 2-(2-oxo-ethylidene)-imidazolidin-4-one and their use to inhibit abnormal cell growth |
WO2000035956A1 (fr) | 1998-12-16 | 2000-06-22 | Kyowa Hakko Kogyo Co., Ltd. | Anticorps monoclonal anti-vegf humain |
ES2243228T3 (es) | 1999-02-11 | 2005-12-01 | Pfizer Products Inc. | Derivados quinolin-2-ona sustituidos con heteroarilo utiles como agentes anticancerigenos. |
US6586447B1 (en) | 1999-04-01 | 2003-07-01 | Pfizer Inc | 3,3-disubstituted-oxindole derivatives useful as anticancer agents |
JP5623681B2 (ja) | 1999-05-14 | 2014-11-12 | ジェネンテック, インコーポレイテッド | 抗−ErbB2抗体による治療 |
US6949245B1 (en) * | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
DK1189634T3 (da) | 1999-06-25 | 2007-06-25 | Genentech Inc | Behandling af prostatacancer med anti-ErbB2-antistoffer |
CN101518653B (zh) | 1999-06-25 | 2015-08-19 | 基因技术股份有限公司 | 使用抗ErbB抗体-类美坦素偶联物的治疗方法 |
UA75055C2 (uk) | 1999-11-30 | 2006-03-15 | Пфайзер Продактс Інк. | Похідні бензоімідазолу, що використовуються як антипроліферативний засіб, фармацевтична композиція на їх основі |
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HN2000000266A (es) | 2000-01-21 | 2001-05-21 | Pfizer Prod Inc | Compuesto anticanceroso y metodo de separacion de enantiomeros util para sintetizar dicho compuesto. |
CA2466279A1 (en) * | 2001-11-13 | 2003-05-22 | Dana-Farber Cancer Institute, Inc. | Agents that modulate immune cell activation and methods of use thereof |
US20060036086A1 (en) | 2002-03-12 | 2006-02-16 | Jain Rakesh K | Use of signal transduction inhibitors and combination therapies for the prevention or treatment of cancer and angiogenesis related diseases |
EP1501856B1 (en) | 2002-04-10 | 2012-12-19 | Genentech, Inc. | Anti-her2 antibody variants |
CN1829741A (zh) | 2003-05-30 | 2006-09-06 | 健泰科生物技术公司 | 利用抗-vegf抗体的治疗 |
WO2005000090A2 (en) | 2003-05-30 | 2005-01-06 | Medi-Screw, Inc. | Medical implant systems |
CA2534055A1 (en) | 2003-08-01 | 2005-02-10 | Genentech, Inc. | Antibody cdr polypeptide sequences with restricted diversity |
US20050106667A1 (en) * | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
PL1718677T3 (pl) | 2003-12-19 | 2012-09-28 | Genentech Inc | Jednowartościowe fragmenty przeciwciała stosowane jako środki lecznicze |
CA2577082A1 (en) * | 2004-09-02 | 2006-03-16 | Genentech, Inc. | Heteromultimeric molecules |
BRPI0515670A (pt) * | 2004-10-04 | 2008-07-29 | Genentech Inc | anticorpos isolados e método de tratamento de uma doença associada com descontrole da sinalização do hgf/c-met |
NZ564243A (en) * | 2005-06-08 | 2011-03-31 | Dana Farber Cancer Inst Inc | Methods and compositions for the treatment of persistent infections by inhibiting the programmed cell death 1 (PD-1) pathway |
TW200812615A (en) * | 2006-03-22 | 2008-03-16 | Hoffmann La Roche | Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 |
PL2056874T3 (pl) * | 2006-08-21 | 2013-02-28 | Hoffmann La Roche | Leczenie nowotworu przeciwciałem przeciw VEGF |
JP2013103182A (ja) * | 2011-11-15 | 2013-05-30 | Toray Ind Inc | スパイラル型流体分離素子およびその製造方法 |
-
2007
- 2007-08-17 PL PL07786693T patent/PL2056874T3/pl unknown
- 2007-08-17 BR BRPI0715829-7A2A patent/BRPI0715829A2/pt not_active Application Discontinuation
- 2007-08-17 SI SI200731075T patent/SI2056874T1/sl unknown
- 2007-08-17 ES ES07786693T patent/ES2392630T3/es active Active
- 2007-08-17 DK DK07786693.7T patent/DK2056874T3/da active
- 2007-08-17 US US11/840,279 patent/US20080050385A1/en not_active Abandoned
- 2007-08-17 RU RU2009110102/15A patent/RU2528884C2/ru not_active IP Right Cessation
- 2007-08-17 NZ NZ574580A patent/NZ574580A/en not_active IP Right Cessation
- 2007-08-17 SG SG2011060142A patent/SG174090A1/en unknown
- 2007-08-17 CA CA002660681A patent/CA2660681A1/en not_active Abandoned
- 2007-08-17 JP JP2009524943A patent/JP2010501498A/ja active Pending
- 2007-08-17 AR ARP070103667A patent/AR062419A1/es unknown
- 2007-08-17 WO PCT/EP2007/007276 patent/WO2008022746A1/en active Application Filing
- 2007-08-17 CL CL200702404A patent/CL2007002404A1/es unknown
- 2007-08-17 EP EP11193793.4A patent/EP2441472B1/en not_active Revoked
- 2007-08-17 CN CN2007800308557A patent/CN101505792B/zh not_active Expired - Fee Related
- 2007-08-17 MX MX2009001715A patent/MX2009001715A/es active IP Right Grant
- 2007-08-17 ES ES11193793.4T patent/ES2546066T3/es active Active
- 2007-08-17 AU AU2007287794A patent/AU2007287794B2/en not_active Ceased
- 2007-08-17 MY MYPI20090667 patent/MY150756A/en unknown
- 2007-08-17 EP EP07786693A patent/EP2056874B1/en not_active Revoked
- 2007-08-17 KR KR1020097003557A patent/KR101136763B1/ko not_active IP Right Cessation
- 2007-08-20 TW TW099141756A patent/TW201107346A/zh unknown
- 2007-08-20 TW TW096130765A patent/TW200825106A/zh unknown
- 2007-08-20 PE PE2007001129A patent/PE20080911A1/es not_active Application Discontinuation
-
2009
- 2009-01-29 CR CR10590A patent/CR10590A/es not_active Application Discontinuation
- 2009-01-29 NO NO20090450A patent/NO20090450L/no not_active Application Discontinuation
- 2009-01-29 IL IL196810A patent/IL196810A0/en unknown
- 2009-02-19 ZA ZA2009/01200A patent/ZA200901200B/en unknown
- 2009-02-19 MA MA31650A patent/MA30654B1/fr unknown
- 2009-02-24 CO CO09018558A patent/CO6150193A2/es unknown
-
2010
- 2010-02-10 HK HK10101487.6A patent/HK1134441A1/xx not_active IP Right Cessation
- 2010-05-20 US US12/784,309 patent/US20100285010A1/en not_active Abandoned
-
2011
- 2011-05-19 US US13/111,784 patent/US20110223159A1/en not_active Abandoned
-
2012
- 2012-08-14 US US13/585,095 patent/US20130183292A1/en not_active Abandoned
-
2013
- 2013-05-15 JP JP2013103182A patent/JP2013163687A/ja not_active Withdrawn
-
2015
- 2015-03-30 IL IL238045A patent/IL238045A0/en unknown
- 2015-05-13 US US14/711,671 patent/US20150239969A1/en not_active Abandoned
- 2015-08-14 JP JP2015160099A patent/JP2015214582A/ja not_active Ceased
-
2017
- 2017-10-23 US US15/791,285 patent/US20180251536A1/en not_active Abandoned
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