PE20080911A1 - Anticuerpo anti-vegf - Google Patents

Anticuerpo anti-vegf

Info

Publication number
PE20080911A1
PE20080911A1 PE2007001129A PE2007001129A PE20080911A1 PE 20080911 A1 PE20080911 A1 PE 20080911A1 PE 2007001129 A PE2007001129 A PE 2007001129A PE 2007001129 A PE2007001129 A PE 2007001129A PE 20080911 A1 PE20080911 A1 PE 20080911A1
Authority
PE
Peru
Prior art keywords
antibody
vegf antibody
her2
treated
vegf
Prior art date
Application number
PE2007001129A
Other languages
English (en)
Inventor
Thomas Friess
Max Hasmann
Werner Scheuer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37607207&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20080911(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PE20080911A1 publication Critical patent/PE20080911A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

REFERIDA A UN ANTICUERPO ANTI-VEGF TAL COMO BEVACIZUMAB. TAMBIEN ESTA REFERIDA A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE AL ANTICUERPO. DICHO ANTICUERPO ES UTIL EN EL TRATAMIENTO DEL CANCER HER2-POSITIVO QUE YA ES TRATADO O HA SIDO TRATADO CON UN ANTICUERPO ANTI-HER2 TAL COMO TRASTUZUMAB
PE2007001129A 2006-08-21 2007-08-20 Anticuerpo anti-vegf PE20080911A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06017330 2006-08-21

Publications (1)

Publication Number Publication Date
PE20080911A1 true PE20080911A1 (es) 2008-08-15

Family

ID=37607207

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2007001129A PE20080911A1 (es) 2006-08-21 2007-08-20 Anticuerpo anti-vegf

Country Status (29)

Country Link
US (6) US20080050385A1 (es)
EP (2) EP2441472B1 (es)
JP (3) JP2010501498A (es)
KR (1) KR101136763B1 (es)
CN (1) CN101505792B (es)
AR (1) AR062419A1 (es)
AU (1) AU2007287794B2 (es)
BR (1) BRPI0715829A2 (es)
CA (1) CA2660681A1 (es)
CL (1) CL2007002404A1 (es)
CO (1) CO6150193A2 (es)
CR (1) CR10590A (es)
DK (1) DK2056874T3 (es)
ES (2) ES2392630T3 (es)
HK (1) HK1134441A1 (es)
IL (2) IL196810A0 (es)
MA (1) MA30654B1 (es)
MX (1) MX2009001715A (es)
MY (1) MY150756A (es)
NO (1) NO20090450L (es)
NZ (1) NZ574580A (es)
PE (1) PE20080911A1 (es)
PL (1) PL2056874T3 (es)
RU (1) RU2528884C2 (es)
SG (1) SG174090A1 (es)
SI (1) SI2056874T1 (es)
TW (2) TW201107346A (es)
WO (1) WO2008022746A1 (es)
ZA (1) ZA200901200B (es)

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KR20130089280A (ko) 2005-01-21 2013-08-09 제넨테크, 인크. Ｈｅｒ 항체의 고정 용량 투여법
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PE20070207A1 (es) * 2005-07-22 2007-03-09 Genentech Inc Tratamiento combinado de los tumores que expresan el her
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BRPI0808418A2 (pt) 2007-03-02 2014-07-22 Genentech Inc Predição de resposta a um inibidor de her
TWI472339B (zh) 2008-01-30 2015-02-11 Genentech Inc 包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物
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CN103153339B (zh) 2010-05-27 2021-05-04 根马布股份公司 针对her2表位的单克隆抗体
CN107253992B (zh) 2010-05-27 2022-03-11 根马布股份公司 针对her2的单克隆抗体
SG187012A1 (en) * 2010-07-19 2013-02-28 Hoffmann La Roche Blood plasma biomarkers for bevacizumab combination therapies for treatment of pancreatic cancer
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JP2014514314A (ja) 2011-04-20 2014-06-19 ゲンマブ エー／エス Ｈｅｒ２およびｃｄ３に対する二重特異性抗体
KR102679155B1 (ko) 2011-10-14 2024-06-28 제넨테크, 인크. Her2 이량체화 억제제인 페르투주맙의 용도 및 이를 포함하는 제조품
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KR20200085942A (ko) 2013-04-16 2020-07-15 제넨테크, 인크. 페르투주맙 변이체 및 그의 평가
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TW201619200A (zh) * 2014-10-10 2016-06-01 麥迪紐有限責任公司 人類化抗－ｏｘ４０抗體及其用途
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TW202140776A (zh) * 2016-04-26 2021-11-01 美商美國泰福生技股份有限公司 細胞培養基
JP6914336B2 (ja) 2016-12-28 2021-08-04 ジェネンテック， インコーポレイテッド 進行したｈｅｒ２発現がんの治療
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HRP20240069T1 (hr) 2017-03-02 2024-03-29 Genentech, Inc. Adjuvantno liječenje her2-pozitivnog raka dojke
AU2018258263A1 (en) 2017-04-24 2019-10-24 Genentech, Inc. ErbB2/Her2 mutations in the transmembrane or juxtamembrane domain
JP2023541141A (ja) * 2020-09-04 2023-09-28 ザ ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ がんを治療するための組み合わせ組成物及び方法

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Also Published As

Publication number Publication date
EP2056874B1 (en) 2012-09-19
CO6150193A2 (es) 2010-04-20
US20180251536A1 (en) 2018-09-06
TW200825106A (en) 2008-06-16
JP2015214582A (ja) 2015-12-03
KR101136763B1 (ko) 2012-04-24
BRPI0715829A2 (pt) 2013-07-23
RU2528884C2 (ru) 2014-09-20
ES2392630T3 (es) 2012-12-12
NZ574580A (en) 2011-12-22
KR20090032136A (ko) 2009-03-31
JP2010501498A (ja) 2010-01-21
MX2009001715A (es) 2009-02-25
AU2007287794B2 (en) 2013-03-28
SG174090A1 (en) 2011-09-29
CA2660681A1 (en) 2008-02-28
CN101505792A (zh) 2009-08-12
HK1134441A1 (en) 2010-04-30
ES2546066T3 (es) 2015-09-18
ZA200901200B (en) 2013-08-28
US20100285010A1 (en) 2010-11-11
WO2008022746A1 (en) 2008-02-28
AU2007287794A1 (en) 2008-02-28
RU2009110102A (ru) 2010-09-27
JP2013163687A (ja) 2013-08-22
US20130183292A1 (en) 2013-07-18
NO20090450L (no) 2009-02-27
TW201107346A (en) 2011-03-01
US20150239969A1 (en) 2015-08-27
US20110223159A1 (en) 2011-09-15
EP2056874A1 (en) 2009-05-13
MY150756A (en) 2014-02-28
EP2441472B1 (en) 2015-06-10
IL238045A0 (en) 2015-05-31
US20080050385A1 (en) 2008-02-28
MA30654B1 (fr) 2009-08-03
CN101505792B (zh) 2012-10-03
DK2056874T3 (da) 2012-10-15
AR062419A1 (es) 2008-11-05
CL2007002404A1 (es) 2008-04-18
IL196810A0 (en) 2011-08-01
CR10590A (es) 2009-03-20
EP2441472A1 (en) 2012-04-18
SI2056874T1 (sl) 2012-12-31
PL2056874T3 (pl) 2013-02-28

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