BRPI0820410A2 - Lactans substituídos terapêuticos - Google Patents
Lactans substituídos terapêuticosInfo
- Publication number
- BRPI0820410A2 BRPI0820410A2 BRPI0820410-1A BRPI0820410A BRPI0820410A2 BR PI0820410 A2 BRPI0820410 A2 BR PI0820410A2 BR PI0820410 A BRPI0820410 A BR PI0820410A BR PI0820410 A2 BRPI0820410 A2 BR PI0820410A2
- Authority
- BR
- Brazil
- Prior art keywords
- lactans
- therapeutic substituted
- therapeutic
- substituted
- substituted lactans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98191807P | 2007-10-23 | 2007-10-23 | |
US98483807P | 2007-11-02 | 2007-11-02 | |
PCT/US2008/080063 WO2009055289A2 (en) | 2007-10-23 | 2008-10-16 | Therapeutic substituted lactams |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0820410A2 true BRPI0820410A2 (pt) | 2015-05-19 |
Family
ID=40521508
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0820410-1A BRPI0820410A2 (pt) | 2007-10-23 | 2008-10-16 | Lactans substituídos terapêuticos |
Country Status (12)
Country | Link |
---|---|
US (1) | US7998998B2 (pt) |
EP (1) | EP2215084B1 (pt) |
JP (1) | JP5410438B2 (pt) |
KR (1) | KR20100086485A (pt) |
CN (1) | CN101868455B (pt) |
AU (1) | AU2008317107B2 (pt) |
BR (1) | BRPI0820410A2 (pt) |
CA (1) | CA2703479C (pt) |
IL (1) | IL205278A0 (pt) |
MX (1) | MX2010004487A (pt) |
NZ (1) | NZ585103A (pt) |
WO (1) | WO2009055289A2 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5524047B2 (ja) * | 2007-05-23 | 2014-06-18 | アラーガン インコーポレイテッド | 緑内障および眼圧上昇の治療用環状ラクタム類 |
DK3175852T3 (da) | 2012-07-19 | 2019-05-27 | Cayman Chemical Co Inc | Difluorlactamsammensætninger til EP4-medierede osteorelaterede sygdomme og tilstande |
CA2882138C (en) * | 2012-08-21 | 2020-10-27 | Allergan, Inc. | Process for the synthesis of substituted gamma lactams |
CN103665043B (zh) | 2012-08-30 | 2017-11-10 | 江苏豪森药业集团有限公司 | 一种替诺福韦前药及其在医药上的应用 |
WO2014144610A1 (en) | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions |
ES2635635T3 (es) | 2013-03-15 | 2017-10-04 | Cayman Chemical Company, Incorporated | Compuestos de difluorolactama como agonistas selectivos del receptor EP4 para su uso en el tratamiento de enfermedades y afecciones mediadas por EP4 |
WO2014144500A2 (en) | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Methods of synthesizing a difluorolactam analog |
JP2016527006A (ja) | 2013-07-19 | 2016-09-08 | ケイマン ケミカル カンパニー, インコーポレーテッド | 骨成長を促進するための方法、システム、及び組成物 |
US9540357B1 (en) | 2014-07-31 | 2017-01-10 | Allergan, Inc. | 15-aryl prostaglandins as EP4 agonists, and methods of use thereof |
KR20230033445A (ko) | 2021-09-01 | 2023-03-08 | 에스케이하이닉스 주식회사 | 반도체 웨이퍼의 불량 분석 방법 및 그 시스템 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4035961A1 (de) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
ES2254726T3 (es) * | 2001-07-16 | 2006-06-16 | F. Hoffmann-La Roche Ag | Analogos de prostaglandina como agonistas receptores de ep4. |
BRPI0407827B8 (pt) * | 2003-02-26 | 2021-05-25 | Sugen Inc | compostos de aminoeteroarila como inibidores de proteína cinase e respectivos usos |
NZ551077A (en) * | 2004-05-07 | 2009-05-31 | Janssen Pharmaceutica Nv | Pyrrolidin-2-one and piperidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
JPWO2007108360A1 (ja) * | 2006-03-17 | 2009-08-06 | 株式会社アイ・ピー・ビー | 細径盲管を用いた表面増強ラマン散乱による物質検知方法および物質検知装置、複数物質検知デバイス、盲管 |
EP2118094B1 (en) * | 2007-02-15 | 2013-04-17 | Allergan, Inc. | Gamma-lactams for the treatment of glaucoma or elevated intraocular pressure |
-
2008
- 2008-10-16 MX MX2010004487A patent/MX2010004487A/es active IP Right Grant
- 2008-10-16 AU AU2008317107A patent/AU2008317107B2/en not_active Ceased
- 2008-10-16 JP JP2010531133A patent/JP5410438B2/ja not_active Expired - Fee Related
- 2008-10-16 CA CA2703479A patent/CA2703479C/en not_active Expired - Fee Related
- 2008-10-16 BR BRPI0820410-1A patent/BRPI0820410A2/pt not_active IP Right Cessation
- 2008-10-16 EP EP08842624.2A patent/EP2215084B1/en not_active Not-in-force
- 2008-10-16 US US12/739,676 patent/US7998998B2/en active Active
- 2008-10-16 CN CN2008801167781A patent/CN101868455B/zh not_active Expired - Fee Related
- 2008-10-16 KR KR1020107010956A patent/KR20100086485A/ko not_active Application Discontinuation
- 2008-10-16 NZ NZ585103A patent/NZ585103A/en not_active IP Right Cessation
- 2008-10-16 WO PCT/US2008/080063 patent/WO2009055289A2/en active Application Filing
-
2010
- 2010-04-22 IL IL205278A patent/IL205278A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2011500818A (ja) | 2011-01-06 |
KR20100086485A (ko) | 2010-07-30 |
AU2008317107B2 (en) | 2013-09-12 |
WO2009055289A2 (en) | 2009-04-30 |
WO2009055289A3 (en) | 2009-06-11 |
MX2010004487A (es) | 2010-05-05 |
NZ585103A (en) | 2012-04-27 |
EP2215084B1 (en) | 2016-09-28 |
JP5410438B2 (ja) | 2014-02-05 |
CA2703479A1 (en) | 2009-04-30 |
EP2215084A2 (en) | 2010-08-11 |
AU2008317107A1 (en) | 2009-04-30 |
CA2703479C (en) | 2017-08-22 |
IL205278A0 (en) | 2010-12-30 |
CN101868455B (zh) | 2013-11-13 |
US20100292293A1 (en) | 2010-11-18 |
RU2010120015A (ru) | 2011-11-27 |
CN101868455A (zh) | 2010-10-20 |
US7998998B2 (en) | 2011-08-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |