ATE501136T1 - Imidazopyridinone - Google Patents
ImidazopyridinoneInfo
- Publication number
- ATE501136T1 ATE501136T1 AT08788941T AT08788941T ATE501136T1 AT E501136 T1 ATE501136 T1 AT E501136T1 AT 08788941 T AT08788941 T AT 08788941T AT 08788941 T AT08788941 T AT 08788941T AT E501136 T1 ATE501136 T1 AT E501136T1
- Authority
- AT
- Austria
- Prior art keywords
- imidazopyridinone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95370707P | 2007-08-03 | 2007-08-03 | |
| PCT/IB2008/001962 WO2009019553A2 (en) | 2007-08-03 | 2008-07-22 | Imidazopyridinones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE501136T1 true ATE501136T1 (de) | 2011-03-15 |
Family
ID=40193849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08788941T ATE501136T1 (de) | 2007-08-03 | 2008-07-22 | Imidazopyridinone |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20090221631A1 (de) |
| EP (1) | EP2188280B1 (de) |
| JP (1) | JP2010535755A (de) |
| AR (1) | AR067757A1 (de) |
| AT (1) | ATE501136T1 (de) |
| CA (1) | CA2707030A1 (de) |
| CL (1) | CL2008002228A1 (de) |
| DE (1) | DE602008005470D1 (de) |
| ES (1) | ES2359123T3 (de) |
| PA (1) | PA8791701A1 (de) |
| PE (1) | PE20090511A1 (de) |
| TW (1) | TW200914003A (de) |
| UY (1) | UY31261A1 (de) |
| WO (1) | WO2009019553A2 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2364314T3 (da) * | 2008-12-09 | 2014-05-12 | Gilead Sciences Inc | Modulatorer af toll-lignende receptorer |
| JP5988492B2 (ja) | 2009-09-02 | 2016-09-07 | ノバルティス アーゲー | Ｔｌｒ活性モジュレーターを含む免疫原性組成物 |
| ES2661850T3 (es) * | 2009-09-14 | 2018-04-04 | Gilead Sciences, Inc. | Moduladores de receptores del tipo toll |
| ES2644286T3 (es) | 2009-10-22 | 2017-11-28 | Gilead Sciences, Inc. | Derivados de purina o deazapurina útiles para el tratamiento de (entre otros) infecciones víricas |
| JP5689321B2 (ja) * | 2010-01-21 | 2015-03-25 | 石原産業株式会社 | ２−アミノ−４−トリフルオロメチルピリジン類の製造方法 |
| EP2480253B1 (de) | 2010-09-01 | 2014-01-22 | Novartis AG | Adsorption von immunpotentiatoren auf unlöslichen metallsalzen |
| EP2471776A1 (de) | 2010-12-28 | 2012-07-04 | Bayer CropScience AG | Pyridin-2-ylpropandinitrile und deren Verwendung als Herbizide |
| AU2012222883A1 (en) * | 2011-03-02 | 2013-10-17 | Novartis Ag | Combination vaccines with lower doses of antigen and/or adjuvant |
| BR112014004782A2 (pt) | 2011-09-01 | 2017-03-21 | Novartis Ag | formulações adjuvantes de antígenos de staphylococcus aureus |
| JP2015509520A (ja) | 2012-03-07 | 2015-03-30 | ノバルティス アーゲー | 狂犬病ウイルス免疫原のアジュバント化製剤 |
| JP2015510872A (ja) | 2012-03-07 | 2015-04-13 | ノバルティス アーゲー | Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ抗原の増強された製剤 |
| CN104159602B (zh) | 2012-03-08 | 2017-10-24 | 葛兰素史密丝克莱恩生物有限公司 | 加强疫苗的含佐剂制剂 |
| RU2015106930A (ru) | 2012-09-06 | 2016-10-20 | Новартис Аг | Комбинированные вакцины с менингококком серогруппы в и к/д/с |
| WO2015023958A1 (en) * | 2013-08-15 | 2015-02-19 | The University Of Kansas | Toll-like receptor agonists |
| TWI733652B (zh) | 2014-07-11 | 2021-07-21 | 美商基利科學股份有限公司 | 用於治療ＨＩＶ之ｔｏｌｌ樣受體調節劑 |
| SG11201701169XA (en) | 2014-08-15 | 2017-03-30 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | Pyrrolopyrimidine compounds used as tlr7 agonist |
| CA2960436C (en) | 2014-09-16 | 2021-01-05 | Gilead Sciences, Inc. | Solid forms of a toll-like receptor modulator |
| CN107043380A (zh) | 2016-02-05 | 2017-08-15 | 正大天晴药业集团股份有限公司 | 一种tlr7激动剂的马来酸盐、其晶型c、晶型d、晶型e、制备方法和用途 |
| US11485741B2 (en) | 2018-04-24 | 2022-11-01 | Bristol-Myers Squibb Company | Macrocyclic toll-like receptor 7 (TLR7) agonists |
| US11554120B2 (en) | 2018-08-03 | 2023-01-17 | Bristol-Myers Squibb Company | 1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor |
| CN121426803A (zh) | 2018-09-12 | 2026-01-30 | 诺华股份有限公司 | 抗病毒吡啶并吡嗪二酮化合物 |
| US11667613B2 (en) | 2019-09-26 | 2023-06-06 | Novartis Ag | Antiviral pyrazolopyridinone compounds |
| CN115135655B (zh) | 2020-01-27 | 2024-07-02 | 百时美施贵宝公司 | 作为Toll样受体7(TLR7)激动剂的1H-吡唑并[4,3-d]嘧啶化合物 |
| CN115210236A (zh) | 2020-01-27 | 2022-10-18 | 百时美施贵宝公司 | 作为Toll样受体7(TLR7)激动剂的1H-吡唑并[4,3-d]嘧啶化合物 |
| CN115151547A (zh) | 2020-01-27 | 2022-10-04 | 百时美施贵宝公司 | 作为Toll样受体7(TLR7)激动剂的1H-吡唑并[4,3-d]嘧啶化合物 |
| EP4097107A1 (de) | 2020-01-27 | 2022-12-07 | Bristol-Myers Squibb Company | C3-substituierte 1h-pyrazolo[ 4,3-d]pyrimidin-verbindungen als toll-like-rezeptor-7(tlr7)-agonisten |
| EP4097100A1 (de) | 2020-01-27 | 2022-12-07 | Bristol-Myers Squibb Company | 1h-pyrazolo[4,3-d]pyrimidin-verbindungen als toll-like-rezeptor-7(tlr7)-agonisten |
| US20230144824A1 (en) | 2020-01-27 | 2023-05-11 | Bristol-Myers Squibb Company | 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS |
| US20230140430A1 (en) | 2020-01-27 | 2023-05-04 | Bristol-Myers Squibb Company | 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS |
| WO2021154663A1 (en) | 2020-01-27 | 2021-08-05 | Bristol-Myers Squibb Company | 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS |
| EP4097105A1 (de) | 2020-01-27 | 2022-12-07 | Bristol-Myers Squibb Company | 1h-pyrazolo[4,3-d]pyrimidinverbindungen als toll-like rezeptor 7 (tlr7)-agonisten |
| CN117736210A (zh) * | 2021-01-28 | 2024-03-22 | 上海翊石医药科技有限公司 | 一类芳杂环类化合物及其制备方法和用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4584335B2 (ja) * | 2005-09-02 | 2010-11-17 | ファイザー・インク | ヒドロキシ置換１ｈ−イミダゾピリジンおよび方法 |
| BRPI0707945A2 (pt) * | 2006-02-17 | 2011-05-17 | Pfizer Ltd | derivados de 3-deazapurina como modulares de tlr7 |
-
2008
- 2008-07-22 AT AT08788941T patent/ATE501136T1/de not_active IP Right Cessation
- 2008-07-22 WO PCT/IB2008/001962 patent/WO2009019553A2/en not_active Ceased
- 2008-07-22 EP EP08788941A patent/EP2188280B1/de not_active Not-in-force
- 2008-07-22 ES ES08788941T patent/ES2359123T3/es active Active
- 2008-07-22 DE DE602008005470T patent/DE602008005470D1/de active Active
- 2008-07-22 JP JP2010519534A patent/JP2010535755A/ja not_active Withdrawn
- 2008-07-22 CA CA2707030A patent/CA2707030A1/en not_active Abandoned
- 2008-07-29 CL CL2008002228A patent/CL2008002228A1/es unknown
- 2008-07-30 PA PA20088791701A patent/PA8791701A1/es unknown
- 2008-07-31 UY UY31261A patent/UY31261A1/es not_active Application Discontinuation
- 2008-07-31 AR ARP080103322A patent/AR067757A1/es not_active Application Discontinuation
- 2008-08-01 PE PE2008001300A patent/PE20090511A1/es not_active Application Discontinuation
- 2008-08-01 TW TW097129257A patent/TW200914003A/zh unknown
-
2009
- 2009-05-15 US US12/184,494 patent/US20090221631A1/en not_active Abandoned
-
2010
- 2010-10-28 US US12/914,530 patent/US20110039884A1/en not_active Abandoned
-
2011
- 2011-11-22 US US13/302,085 patent/US20120302598A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| TW200914003A (en) | 2009-04-01 |
| EP2188280A2 (de) | 2010-05-26 |
| EP2188280B1 (de) | 2011-03-09 |
| AR067757A1 (es) | 2009-10-21 |
| PA8791701A1 (es) | 2009-04-23 |
| US20120302598A1 (en) | 2012-11-29 |
| ES2359123T3 (es) | 2011-05-18 |
| CL2008002228A1 (es) | 2009-04-17 |
| US20110039884A1 (en) | 2011-02-17 |
| CA2707030A1 (en) | 2009-02-12 |
| US20090221631A1 (en) | 2009-09-03 |
| UY31261A1 (es) | 2009-03-31 |
| DE602008005470D1 (en) | 2011-04-21 |
| PE20090511A1 (es) | 2009-05-07 |
| JP2010535755A (ja) | 2010-11-25 |
| WO2009019553A3 (en) | 2009-04-02 |
| WO2009019553A2 (en) | 2009-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |