AU2010246608B2 - 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors - Google Patents

7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors Download PDF

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Publication number
AU2010246608B2
AU2010246608B2 AU2010246608A AU2010246608A AU2010246608B2 AU 2010246608 B2 AU2010246608 B2 AU 2010246608B2 AU 2010246608 A AU2010246608 A AU 2010246608A AU 2010246608 A AU2010246608 A AU 2010246608A AU 2010246608 B2 AU2010246608 B2 AU 2010246608B2
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alkyl
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halo
chloro
substituted
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AU2010246608A1 (en
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Jose Maria Cid-Nunez
Ana Isabel De Lucas Olivares
Gregor James Macdonald
Andres Avelino Trabanco-Suarez
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Addex Pharmaceuticals SA
Janssen Pharmaceuticals Inc
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Addex Pharmaceuticals SA
Janssen Pharmaceuticals Inc
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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AU2010246608A 2009-05-12 2010-05-11 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors Ceased AU2010246608B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09160064 2009-05-12
EP09160064.3 2009-05-12
PCT/EP2010/002909 WO2010130423A1 (en) 2009-05-12 2010-05-11 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors

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AU2010246608A1 AU2010246608A1 (en) 2011-11-17
AU2010246608B2 true AU2010246608B2 (en) 2012-10-11

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AU2010246608A Ceased AU2010246608B2 (en) 2009-05-12 2010-05-11 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors

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US (2) US8716480B2 (OSRAM)
EP (1) EP2430021B1 (OSRAM)
JP (1) JP5707391B2 (OSRAM)
KR (1) KR20120039532A (OSRAM)
CN (1) CN102439009B (OSRAM)
AR (1) AR076860A1 (OSRAM)
AU (1) AU2010246608B2 (OSRAM)
CA (1) CA2760084C (OSRAM)
CL (1) CL2011002839A1 (OSRAM)
EA (1) EA020556B1 (OSRAM)
ES (1) ES2428401T3 (OSRAM)
IL (1) IL215911A (OSRAM)
MX (1) MX2011011963A (OSRAM)
MY (1) MY153913A (OSRAM)
NZ (1) NZ595945A (OSRAM)
SG (1) SG175931A1 (OSRAM)
TW (1) TW201100415A (OSRAM)
WO (1) WO2010130423A1 (OSRAM)
ZA (1) ZA201107833B (OSRAM)

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GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
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TW200845978A (en) 2007-03-07 2008-12-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
EP2205565B1 (en) 2007-09-14 2013-04-17 Janssen Pharmaceuticals, Inc. 1,3-disubstituted-4-phenyl-1 h-pyridin-2-ones
KR20100065191A (ko) 2007-09-14 2010-06-15 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 １,３-이치환된 ４-(아릴-ｘ-페닐)-１ｈ-피리딘-２-온
MX2010002536A (es) 2007-09-14 2010-08-10 Ortho Mcneil Janssen Pharm 4-fenil-3,4,5,6-tetrahidro-2h, 1'h-[1,4]bipiridinil-2'-onas 1',3'-disubstituidas.
EP2220083B1 (en) * 2007-11-14 2017-07-19 Janssen Pharmaceuticals, Inc. Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
MX2011002042A (es) 2008-09-02 2011-06-20 Ortho Mcneil Janssen Pharm Derivados de 3-azabiciclo[3.1.o]hexilo como moduladores de los receptores del glutamato metabotropico.
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CA2760084A1 (en) 2010-11-18
HK1166784A1 (en) 2012-11-09
IL215911A (en) 2015-02-26
EA020556B1 (ru) 2014-12-30
MY153913A (en) 2015-04-15
TW201100415A (en) 2011-01-01
EP2430021B1 (en) 2013-08-28
AR076860A1 (es) 2011-07-13
AU2010246608A1 (en) 2011-11-17

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