ATE423216T1 - Neue fructosylpeptidoxidase und deren nutzung - Google Patents
Neue fructosylpeptidoxidase und deren nutzungInfo
- Publication number
- ATE423216T1 ATE423216T1 AT03758817T AT03758817T ATE423216T1 AT E423216 T1 ATE423216 T1 AT E423216T1 AT 03758817 T AT03758817 T AT 03758817T AT 03758817 T AT03758817 T AT 03758817T AT E423216 T1 ATE423216 T1 AT E423216T1
- Authority
- AT
- Austria
- Prior art keywords
- fructosylpeptidoxidase
- new
- protein
- enzyme
- fructosylated peptide
- Prior art date
Links
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/725—Haemoglobin using peroxidative activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Metal-Oxide And Bipolar Metal-Oxide Semiconductor Integrated Circuits (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002308731 | 2002-10-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE423216T1 true ATE423216T1 (de) | 2009-03-15 |
Family
ID=32170987
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03758817T ATE423216T1 (de) | 2002-10-23 | 2003-10-23 | Neue fructosylpeptidoxidase und deren nutzung |
| AT03758816T ATE450619T1 (de) | 2002-10-23 | 2003-10-23 | Defructosylierungsverfahren |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03758816T ATE450619T1 (de) | 2002-10-23 | 2003-10-23 | Defructosylierungsverfahren |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7329520B2 (de) |
| EP (2) | EP1555324B1 (de) |
| JP (2) | JP4327094B2 (de) |
| AT (2) | ATE423216T1 (de) |
| AU (2) | AU2003275613A1 (de) |
| DE (2) | DE60330376D1 (de) |
| WO (2) | WO2004038034A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
| TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| ES2409215T3 (es) | 2007-09-14 | 2013-06-25 | Janssen Pharmaceuticals, Inc. | 4-fenil-1H-piridin-2-onas 1-3-disustituidas |
| BRPI0817101A2 (pt) | 2007-09-14 | 2017-05-09 | Addex Pharmaceuticals Sa | 4-(aril-x-fenil)-1h-piridin-2-onas 1,3-dissubstituídas |
| SI2203439T1 (sl) | 2007-09-14 | 2011-05-31 | Ortho Mcneil Janssen Pharm | 1',3'-disubstituirani 4-fenil-3,4,5,6-tetrahidro-2H-1'H-(1,4')bipiridinil-2'-oni |
| ES2637794T3 (es) | 2007-11-14 | 2017-10-17 | Janssen Pharmaceuticals, Inc. | Derivados de imidazo[1,2-A]piridina y su uso como moduladores alostéricos positivos de receptores MGLUR2 |
| ES2439291T3 (es) | 2008-09-02 | 2014-01-22 | Janssen Pharmaceuticals, Inc. | Derivados de 3-azabiciclo[3.1.0]hexilo como moduladores de receptores de glutamato metabotrópicos |
| CA2739881A1 (en) | 2008-10-09 | 2010-04-15 | Kyowa Medex Co., Ltd. | Novel fructosyl peptide oxidase |
| CA2738849C (en) | 2008-10-16 | 2016-06-28 | Addex Pharma S.A. | Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors |
| ES2401691T3 (es) | 2008-11-28 | 2013-04-23 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Derivados de indol y de benzoxacina como moduladores de los receptores metabotrópicos de glutamato |
| ES2440001T3 (es) | 2009-05-12 | 2014-01-27 | Janssen Pharmaceuticals, Inc. | Derivados de 1,2,4-triazolo[4,3-A]piridina y su uso para el tratamiento o prevención de trastornos neurológicos y psiquiátricos |
| MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| SG176018A1 (en) | 2009-05-12 | 2011-12-29 | Janssen Pharmaceuticals Inc | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| CA2814998C (en) | 2010-11-08 | 2019-10-29 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| ES2552455T3 (es) | 2010-11-08 | 2015-11-30 | Janssen Pharmaceuticals, Inc. | Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2 |
| CN103298809B (zh) | 2010-11-08 | 2016-08-31 | 杨森制药公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途 |
| JP5858945B2 (ja) | 2012-03-15 | 2016-02-10 | アークレイ株式会社 | 酵素を用いた測定方法 |
| WO2013162035A1 (ja) | 2012-04-27 | 2013-10-31 | キッコーマン株式会社 | フルクトシルヘキサペプチドに作用する改変型アマドリアーゼ |
| JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
| JP6623488B2 (ja) | 2013-07-09 | 2019-12-25 | 日立化成ダイアグノスティックス・システムズ株式会社 | 糖化ヘモグロビンの測定方法 |
| US9944970B2 (en) | 2013-07-09 | 2018-04-17 | Kyowa Medex Co., Ltd. | Glycated hexapeptide oxidase and use thereof |
| JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
| WO2015060431A1 (ja) * | 2013-10-25 | 2015-04-30 | キッコーマン株式会社 | 糖化ペプチドに作用するアマドリアーゼを用いたＨｂＡ１ｃ測定法 |
| WO2015060429A1 (ja) * | 2013-10-25 | 2015-04-30 | キッコーマン株式会社 | ヘモグロビンＡ１ｃの測定方法および測定キット |
| IL279202B2 (en) | 2014-01-21 | 2023-09-01 | Janssen Pharmaceutica Nv | Combinations containing positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic subtype 2 receptor and their use |
| US10537573B2 (en) | 2014-01-21 | 2020-01-21 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
| US10934530B2 (en) | 2015-04-03 | 2021-03-02 | Kikkoman Corporation | Amadoriase having improved specific activity |
| EP3447132B1 (de) * | 2016-04-22 | 2022-05-18 | Kikkoman Corporation | Hba1c-dehydrogenase |
| CN108342370B (zh) * | 2017-01-22 | 2021-05-28 | 上海交通大学 | 一种新型果糖基肽氧化酶及其应用 |
| US12258589B2 (en) | 2017-08-31 | 2025-03-25 | Kikkoman Corporation | Glycated hemoglobin oxidase variant and method for measurement |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60109509A (ja) * | 1983-11-16 | 1985-06-15 | Narisu Keshohin:Kk | 美白化粧料 |
| US4976974A (en) * | 1988-06-02 | 1990-12-11 | Chateau Yaldara Pty. Ltd. | Grape juice concentrate and drink |
| GB9116315D0 (en) | 1991-07-29 | 1991-09-11 | Genzyme Ltd | Assay |
| JP3157622B2 (ja) | 1992-06-05 | 2001-04-16 | 株式会社ミツカングループ本社 | フルクトシルアミンデグリカーゼ、その製造法及び該酵素を用いたアマドリ化合物の定量方法 |
| AU661207B2 (en) * | 1992-11-17 | 1995-07-13 | Boehringer Mannheim Gmbh | Simultaneous determination of HbA1c and haemoglobin variants with a glycation analogus to HbA1c |
| JP2923222B2 (ja) | 1994-03-03 | 1999-07-26 | 株式会社京都第一科学 | フルクトシルアミノ酸オキシダーゼ及びその製造方法 |
| JP3850904B2 (ja) | 1994-10-05 | 2006-11-29 | アークレイ株式会社 | フルクトシルアミノ酸オキシダーゼ及びその製造方法 |
| JP4004081B2 (ja) | 1995-04-11 | 2007-11-07 | アークレイ株式会社 | フルクトシルアミノ酸オキシダーゼおよびその製造方法 |
| US5741491A (en) * | 1995-09-06 | 1998-04-21 | Isotechnika Incorporated | Medicinal composition for diabetes |
| WO1997013872A1 (en) | 1995-10-12 | 1997-04-17 | Kyoto Daiichi Kagaku Co., Ltd. | Method and assaying amodori compounds |
| WO1998027827A1 (en) * | 1996-12-23 | 1998-07-02 | Dsm N.V. | Method for producing a protein hydrolysate |
| JPH11155579A (ja) * | 1997-11-25 | 1999-06-15 | Kikkoman Corp | フルクトシルアミノ酸オキシダーゼ遺伝子、新規な組み換え体ｄｎａ及びフルクトシルアミノ酸オキシダーゼの製造法 |
| IN186667B (de) * | 1999-01-29 | 2001-10-20 | Ajanta Pharma Ltd | |
| JP2000333696A (ja) | 1999-05-26 | 2000-12-05 | Arkray Inc | 糖化アミンの測定方法 |
| JP3734212B2 (ja) | 1999-08-18 | 2006-01-11 | 旭化成ファーマ株式会社 | タンパク質の選択的断片化方法 |
| JP4427137B2 (ja) * | 1999-08-23 | 2010-03-03 | 積水メディカル株式会社 | フルクトシルバリンの生産方法 |
| JP3949854B2 (ja) | 1999-10-01 | 2007-07-25 | キッコーマン株式会社 | 糖化蛋白質の測定方法 |
| US7235378B2 (en) | 2000-07-14 | 2007-06-26 | Arkray, Inc. | Method of selectively determining glycated hemoglobin |
| DE60139893D1 (de) | 2000-11-28 | 2009-10-22 | Kikkoman Corp | Neue fructosyl-aminosäureoxidase |
| WO2004029251A1 (ja) * | 2002-09-24 | 2004-04-08 | Arkray, Inc. | フルクトシルアミンオキシダーゼ |
-
2003
- 2003-10-23 EP EP03758816A patent/EP1555324B1/de not_active Expired - Lifetime
- 2003-10-23 WO PCT/JP2003/013548 patent/WO2004038034A1/ja not_active Ceased
- 2003-10-23 EP EP03758817A patent/EP1555325B1/de not_active Expired - Lifetime
- 2003-10-23 AU AU2003275613A patent/AU2003275613A1/en not_active Abandoned
- 2003-10-23 AU AU2003275612A patent/AU2003275612A1/en not_active Abandoned
- 2003-10-23 JP JP2004546459A patent/JP4327094B2/ja not_active Expired - Fee Related
- 2003-10-23 WO PCT/JP2003/013547 patent/WO2004038033A1/ja not_active Ceased
- 2003-10-23 AT AT03758817T patent/ATE423216T1/de not_active IP Right Cessation
- 2003-10-23 AT AT03758816T patent/ATE450619T1/de not_active IP Right Cessation
- 2003-10-23 DE DE60330376T patent/DE60330376D1/de not_active Expired - Lifetime
- 2003-10-23 DE DE60326259T patent/DE60326259D1/de not_active Expired - Lifetime
- 2003-10-23 US US10/531,305 patent/US7329520B2/en not_active Expired - Fee Related
- 2003-10-23 JP JP2004546460A patent/JP4323429B2/ja not_active Expired - Fee Related
- 2003-10-23 US US10/531,321 patent/US7393549B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7393549B2 (en) | 2008-07-01 |
| EP1555324A1 (de) | 2005-07-20 |
| JPWO2004038034A1 (ja) | 2006-02-23 |
| EP1555325A4 (de) | 2006-06-07 |
| AU2003275613A1 (en) | 2004-05-13 |
| DE60330376D1 (de) | 2010-01-14 |
| EP1555325B1 (de) | 2009-02-18 |
| US20060240501A1 (en) | 2006-10-26 |
| JPWO2004038033A1 (ja) | 2006-02-23 |
| EP1555324A4 (de) | 2006-06-07 |
| WO2004038034A1 (ja) | 2004-05-06 |
| JP4323429B2 (ja) | 2009-09-02 |
| ATE450619T1 (de) | 2009-12-15 |
| JP4327094B2 (ja) | 2009-09-09 |
| EP1555325A1 (de) | 2005-07-20 |
| US20070054344A1 (en) | 2007-03-08 |
| DE60326259D1 (de) | 2009-04-02 |
| EP1555324B1 (de) | 2009-12-02 |
| AU2003275612A1 (en) | 2004-05-13 |
| US7329520B2 (en) | 2008-02-12 |
| WO2004038033A1 (ja) | 2004-05-06 |
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